Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionQ9H6Q3
DateThu Apr 26 09:38:43 BST 2012
Unique Job ID479c4903bafc0cc3

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1y57A_
Top template information
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
Confidence and coverage
Confidence:100.0% Coverage: 82%
215 residues ( 82% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MGSLPSRRKSLPSPSLSSSVQGQGPVTMEAERSKATAVALGSFPAGGPAELSLRLGEPLT
Secondary structure 
















































SS confidence 



























































Disorder  ??????????????????????????????????









????????







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   .........70.........80.........90.........100.........110.........120
Sequence  IVSEDGDWWTVLSEVSGREYNIPSVHVAKVSHGWLYEGLSREKAEELLLLPGNPGGAFLI
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Disorder 





?






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   .........130.........140.........150.........160.........170.........180
Sequence  RESQTRRGSYSLSVRLSRPASWDRIRHYRIHCLDNGWLYISPRLTFPSLQALVDHYSELA
Secondary structure 


























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Disorder 

















??







































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   .........190.........200.........210.........220.........230.........240
Sequence  DDICCLLKEPCVLQRAGPLPGKDIPLPVTVQRTPLNWKELDSSLLFSEAATGEESLLSEG
Secondary structure 





































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Disorder 










??????????????????????????????????????
???






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   .........250.........260.
Sequence  LRESLSFYISLNDEAVSLDDA
Secondary structure 










SS confidence 




















Disorder 











?????????
Disorder confidence 




















 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1y57 chain A

3D model

Region: 35 - 260
Aligned: 215
Modelled: 215
Confidence: 100.0%
Identity: 34%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor

Phyre2

PDB 2fo0 chain A

3D model

Region: 21 - 260
Aligned: 225
Modelled: 240
Confidence: 100.0%
Identity: 28%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase

Phyre2

PDB 2c0i chain A

3D model

Region: 36 - 260
Aligned: 214
Modelled: 225
Confidence: 100.0%
Identity: 35%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983

Phyre2

PDB 2h8h chain A

3D model

Region: 36 - 260
Aligned: 214
Modelled: 214
Confidence: 100.0%
Identity: 34%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor

Phyre2

PDB 1x27 chain F

3D model

Region: 35 - 191
Aligned: 157
Modelled: 157
Confidence: 100.0%
Identity: 44%
PDB header:signaling protein
Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck;
PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas

Phyre2

PDB 3nhn chain A

3D model

Region: 34 - 192
Aligned: 159
Modelled: 159
Confidence: 100.0%
Identity: 45%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region

Phyre2

PDB 1opl chain A

3D model

Region: 33 - 260
Aligned: 213
Modelled: 228
Confidence: 100.0%
Identity: 30%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase

Phyre2

PDB 1k9a chain B

3D model

Region: 28 - 260
Aligned: 216
Modelled: 231
Confidence: 100.0%
Identity: 26%
PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution

Phyre2

PDB 2abl chain A

3D model

Region: 29 - 192
Aligned: 157
Modelled: 164
Confidence: 100.0%
Identity: 32%
PDB header:transferase
Chain: A: PDB Molecule:abl tyrosine kinase;
PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase

Phyre2

PDB 1g83 chain A

3D model

Region: 35 - 190
Aligned: 156
Modelled: 156
Confidence: 100.0%
Identity: 43%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn;
PDBTitle: crystal structure of fyn sh3-sh2

Phyre2

PDB 1a81 chain A domain 1

3D model

Region: 88 - 223
Aligned: 127
Modelled: 136
Confidence: 100.0%
Identity: 27%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 2oq1 chain A domain 1

3D model

Region: 89 - 199
Aligned: 106
Modelled: 111
Confidence: 100.0%
Identity: 29%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 2oq1 chain A

3D model

Region: 90 - 199
Aligned: 105
Modelled: 110
Confidence: 100.0%
Identity: 30%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide

Phyre2

PDB 1lkk chain A

3D model

Region: 89 - 191
Aligned: 103
Modelled: 103
Confidence: 100.0%
Identity: 49%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 2oq1 chain A domain 2

3D model

Region: 84 - 193
Aligned: 104
Modelled: 110
Confidence: 100.0%
Identity: 30%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 2dly chain A

3D model

Region: 77 - 209
Aligned: 120
Modelled: 133
Confidence: 100.0%
Identity: 33%
PDB header:transferase
Chain: A: PDB Molecule:fyn-related kinase;
PDBTitle: solution structure of the sh2 domain of murine fyn-related2 kinase

Phyre2

PDB 1bkl chain A

3D model

Region: 92 - 195
Aligned: 104
Modelled: 104
Confidence: 100.0%
Identity: 42%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 1qcf chain A domain 2

3D model

Region: 92 - 192
Aligned: 101
Modelled: 101
Confidence: 100.0%
Identity: 52%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 1f2f chain A

3D model

Region: 91 - 192
Aligned: 102
Modelled: 102
Confidence: 100.0%
Identity: 43%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 1a81 chain E domain 1

3D model

Region: 88 - 209
Aligned: 109
Modelled: 122
Confidence: 100.0%
Identity: 30%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 2yt6 chain A

3D model

Region: 2 - 105
Aligned: 98
Modelled: 98
Confidence: 99.7%
Identity: 31%
PDB header:cell cycle
Chain: A: PDB Molecule:adult male urinary bladder cdna, riken full-
PDBTitle: solution structure of the sh3_1 domain of yamaguchi sarcoma2 viral (v-yes) oncogene homolog 1

Phyre2
1

c1y57A_
2

c2fo0A_
3

c2c0iA_
4

c2h8hA_
5

c1x27F_
6

c3nhnA_
7

c1oplA_
8

c1k9aB_
9

c2ablA_
10

c1g83A_
11

d1a81a1
12

d2oq1a1
13

c2oq1A_
14

d1lkka_
15

d2oq1a2
16

c2dlyA_
17

d1bkla_
18

d1qcfa2
19

d1f2fa_
20

d1a81e1
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c2yt6A_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1y57A_



100.0 34 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
2c2fo0A_



100.0 28 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
3c2c0iA_



100.0 35 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983
4c2h8hA_



100.0 34 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor
5c1x27F_



100.0 44 PDB header:signaling protein
Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck;
PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas
6c3nhnA_



100.0 45 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region
7c1oplA_



100.0 30 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
8c1k9aB_



100.0 26 PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
9c2ablA_



100.0 32 PDB header:transferase
Chain: A: PDB Molecule:abl tyrosine kinase;
PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase
10c1g83A_



100.0 43 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn;
PDBTitle: crystal structure of fyn sh3-sh2
11d1a81a1



100.0 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
12d2oq1a1



100.0 29 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
13c2oq1A_



100.0 30 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide
14d1lkka_



100.0 49 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
15d2oq1a2



100.0 30 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
16c2dlyA_



100.0 33 PDB header:transferase
Chain: A: PDB Molecule:fyn-related kinase;
PDBTitle: solution structure of the sh2 domain of murine fyn-related2 kinase
17d1bkla_



100.0 42 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
18d1qcfa2



100.0 52 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
19d1f2fa_



100.0 43 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
20d1a81e1



100.0 30 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
21d1blja_



not modelled 100.0 45 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
22d1o48a_



not modelled 100.0 41 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
23d1g83a2



not modelled 100.0 46 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
24c2ozoA_



not modelled 100.0 30 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70
25d1a81a2



not modelled 100.0 34 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
26c2b3oA_



not modelled 100.0 28 PDB header:hydrolase
Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type
PDBTitle: crystal structure of human tyrosine phosphatase shp-1
27c2eo3A_



not modelled 100.0 33 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of the sh2 domain from human crk-like2 protein
28d1rjaa_



not modelled 100.0 34 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
29d1a81e2



not modelled 100.0 35 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
30d1nrva_



not modelled 99.9 24 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
31c2ysxA_



not modelled 99.9 29 PDB header:signaling protein
Chain: A: PDB Molecule:signaling inositol polyphosphate phosphatase
PDBTitle: solution structure of the human ship sh2 domain
32d1csya_



not modelled 99.9 31 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
33c2knoA_



not modelled 99.9 30 PDB header:hydrolase
Chain: A: PDB Molecule:tensin-like c1 domain-containing phosphatase;
PDBTitle: nmr solution structure of sh2 domain of the human tensin like c12 domain containing phosphatase (tenc1)
34c2ge9A_



not modelled 99.9 25 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase btk;
PDBTitle: solution structures of the sh2 domain of bruton's tyrosine2 kinase
35c3ps5A_



not modelled 99.9 29 PDB header:hydrolase, signaling protein
Chain: A: PDB Molecule:tyrosine-protein phosphatase non-receptor type 6;
PDBTitle: crystal structure of the full-length human protein tyrosine2 phosphatase shp-1
36d1cwea_



not modelled 99.9 50 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
37c2shpA_



not modelled 99.9 28 PDB header:tyrosine phosphatase
Chain: A: PDB Molecule:shp-2;
PDBTitle: tyrosine phosphatase shp-2
38c2el8A_



not modelled 99.9 19 PDB header:signaling protein
Chain: A: PDB Molecule:signal-transducing adaptor protein 2;
PDBTitle: solution structure of the human stap2 sh2 domain
39d2qmsa1



not modelled 99.9 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
40c2eo6A_



not modelled 99.9 24 PDB header:signaling protein
Chain: A: PDB Molecule:b-cell linker protein;
PDBTitle: solution structure of the sh2 domain from mouse b-cell2 linker protein blnk
41d1opka2



not modelled 99.9 37 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
42c1ka6A_



not modelled 99.9 25 PDB header:immune system
Chain: A: PDB Molecule:sh2 domain protein 1a;
PDBTitle: sap/sh2d1a bound to peptide n-py
43c1a81E_



not modelled 99.9 29 PDB header:complex (transferase/peptide)
Chain: E: PDB Molecule:syk kinase;
PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam
44d1d4ta_



not modelled 99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
45c2dm0A_



not modelled 99.9 23 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase txk;
PDBTitle: solution structure of the sh2 domain of human tyrosine-2 protein kinase txk
46c3hizB_



not modelled 99.9 27 PDB header:transferase/oncoprotein
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit
PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha
47d1k9aa2



not modelled 99.9 35 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
48c2gsbA_



not modelled 99.9 26 PDB header:signaling protein
Chain: A: PDB Molecule:ras gtpase-activating protein 1;
PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1
49d1luia_



not modelled 99.9 30 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
50c1x6cA_



not modelled 99.9 31 PDB header:signaling protein
Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type
PDBTitle: solution structures of the sh2 domain of human protein-2 tyrosine phosphatase shp-1
51d1i3za_



not modelled 99.9 33 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
52c2y3aB_



not modelled 99.9 33 PDB header:transferase
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta;
PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941
53d2shpa2



not modelled 99.9 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
54d1jwoa_



not modelled 99.9 34 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
55d2shpa3



not modelled 99.9 34 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
56c2ekxA_



not modelled 99.9 25 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic tyrosine-protein kinase bmx;
PDBTitle: solution structure of the human bmx sh2 domain
57d1fhsa_



not modelled 99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
58c2dlzA_



not modelled 99.9 23 PDB header:signaling protein
Chain: A: PDB Molecule:protein vav-2;
PDBTitle: solution structure of the sh2 domain of human protein vav-2
59c2eobA_



not modelled 99.9 31 PDB header:hydrolase
Chain: A: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate
PDBTitle: solution structure of the second sh2 domain from rat plc2 gamma-2
60d2izva2



not modelled 99.9 26 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
61c2crhA_



not modelled 99.9 18 PDB header:signaling protein
Chain: A: PDB Molecule:vav proto-oncogene;
PDBTitle: solution structure of the sh2 domain of human proto-2 oncogene protein vav1
62d1pica_



not modelled 99.9 32 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
63d3c7ia1



not modelled 99.9 32 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
64d2eyva1



not modelled 99.9 38 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
65d1ayaa_



not modelled 99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
66c2lctA_



not modelled 99.9 23 PDB header:signaling protein
Chain: A: PDB Molecule:proto-oncogene vav;
PDBTitle: solution structure of the vav1 sh2 domain complexed with a syk-derived2 doubly phosphorylated peptide
67c2vifA_



not modelled 99.9 22 PDB header:signaling protein
Chain: A: PDB Molecule:suppressor of cytokine signalling 6;
PDBTitle: crystal structure of socs6 sh2 domain in complex with a c-kit2 phosphopeptide
68c3mazA_



not modelled 99.9 20 PDB header:signaling protein
Chain: A: PDB Molecule:signal-transducing adaptor protein 1;
PDBTitle: crystal structure of the human brdg1/stap-1 sh2 domain in complex with2 the ntal ptyr136 peptide
69d2cs0a1



not modelled 99.9 35 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
70c2c9wA_



not modelled 99.9 28 PDB header:transcription regulation
Chain: A: PDB Molecule:suppressor of cytokine signaling 2;
PDBTitle: crystal structure of socs-2 in complex with elongin-b and2 elongin-c at 1.9a resolution
71d1qada_



not modelled 99.9 33 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
72c3gqiB_



not modelled 99.9 26 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:phospholipase c-gamma-1;
PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates
73d2fcia1



not modelled 99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
74c2izvA_



not modelled 99.9 28 PDB header:transcription
Chain: A: PDB Molecule:suppressor of cytokine signaling 4;
PDBTitle: crystal structure of socs-4 in complex with elongin-b and2 elongin-c at 2.55a resolution
75c2hmhA_



not modelled 99.9 26 PDB header:cytokine regulator
Chain: A: PDB Molecule:suppressor of cytokine signaling 3;
PDBTitle: crystal structure of socs3 in complex with gp130(ptyr757)2 phosphopeptide.
76d1r1qa_



not modelled 99.9 38 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
77d1jyra_



not modelled 99.9 35 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
78c2ci8A_



not modelled 99.9 26 PDB header:translation
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: sh2 domain of human nck1 adaptor protein - uncomplexed
79d1fu6a_



not modelled 99.9 29 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
80d2c9wa2



not modelled 99.9 29 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
81c2kk6A_



not modelled 99.9 29 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fer;
PDBTitle: solution structure of sh2 domain of proto-oncogene tyrosine-2 protein kinase fer from homo sapiens, northeast structural3 genomics consortium (nesg) target hr3461d
82c2dcrA_



not modelled 99.9 26 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: fully automated solution structure determination of the fes2 sh2 domain
83d1mila_



not modelled 99.9 29 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
84d1rpya_



not modelled 99.8 31 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
85c1rqqC_



not modelled 99.8 33 PDB header:transferase/signaling protein
Chain: C: PDB Molecule:adaptor protein aps;
PDBTitle: crystal structure of the insulin receptor kinase in complex2 with the sh2 domain of aps
86c2cr4A_



not modelled 99.8 22 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 domain-binding protein 2;
PDBTitle: solution structure of the sh2 domain of human sh3bp2 protein
87d1xa6a2



not modelled 99.8 30 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
88c2dvjA_



not modelled 99.8 31 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog,
PDBTitle: phosphorylated crk-ii
89c2eyzA_



not modelled 99.8 31 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii
90c3gxxB_



not modelled 99.8 19 PDB header:transcription
Chain: B: PDB Molecule:transcription elongation factor spt6;
PDBTitle: structure of the sh2 domain of the candida glabrata2 transcription elongation factor spt6, crystal form b
91c3qwyA_



not modelled 99.8 30 PDB header:signaling protein
Chain: A: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2
92c2eyyA_



not modelled 99.8 31 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i
93c3qwxX_



not modelled 99.8 30 PDB header:signaling protein
Chain: X: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2 1-174
94c2dx0B_



not modelled 99.8 39 PDB header:hydrolase
Chain: B: PDB Molecule:phospholipase c, gamma 2;
PDBTitle: crystal structure of the n-terminal sh2 domain of mouse2 phospholipase c-gamma 2
95c1griA_



not modelled 99.8 27 PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2
96c2yt6A_



99.7 31 PDB header:cell cycle
Chain: A: PDB Molecule:adult male urinary bladder cdna, riken full-
PDBTitle: solution structure of the sh3_1 domain of yamaguchi sarcoma2 viral (v-yes) oncogene homolog 1
97c3or8A_



not modelled 99.7 23 PDB header:transcription
Chain: A: PDB Molecule:transcription elongation factor spt6;
PDBTitle: a tandem sh2 domain in transcription elongation factor spt6
98c2xp1A_



not modelled 99.6 21 PDB header:transcription
Chain: A: PDB Molecule:spt6;
PDBTitle: structure of the tandem sh2 domains from antonospora locustae2 transcription elongation factor spt6
99d1uura3



not modelled 99.6 21 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
100c1xa6A_



not modelled 99.6 25 PDB header:signaling protein
Chain: A: PDB Molecule:beta2-chimaerin;
PDBTitle: crystal structure of the human beta2-chimaerin
101c2cudA_



not modelled 99.5 31 PDB header:signaling protein
Chain: A: PDB Molecule:src-like-adapter;
PDBTitle: solution structure of the sh3 domain of the human src-like2 adopter protein (slap)
102c2jxbA_



not modelled 99.5 19 PDB header:signaling protein complex
Chain: A: PDB Molecule:t-cell surface glycoprotein cd3 epsilon chain,
PDBTitle: structure of cd3epsilon-nck2 first sh3 domain complex
103c2oi3A_



not modelled 99.5 28 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: nmr structure analysis of the hematopoetic cell kinase sh32 domain complexed with an artificial high affinity ligand3 (pd1)
104d1bf5a3



not modelled 99.4 20 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
105c1mv3A_



not modelled 99.4 13 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:myc box dependent interacting protein 1;
PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc
106c1x6gA_



not modelled 99.4 22 PDB header:signaling protein
Chain: A: PDB Molecule:megakaryocyte-associated tyrosine-protein kinase;
PDBTitle: solution structures of the sh3 domain of human2 megakaryocyte-associated tyrosine-protein kinase.
107c2rqrA_



not modelled 99.4 19 PDB header:protein binding
Chain: A: PDB Molecule:engulfment and cell motility protein 1, linker, dedicator
PDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex
108c2yupA_



not modelled 99.4 23 PDB header:cell adhesion
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the second sh3 domain of human vinexin
109c3cblA_



not modelled 99.4 31 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: crystal structure of human feline sarcoma viral oncogene homologue (v-2 fes) in complex with staurosporine and a consensus peptide
110d1lcka1



not modelled 99.3 31 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
111c1x6bA_



not modelled 99.3 14 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine exchange factor (gef) 16;
PDBTitle: solution structures of the sh3 domain of human rho guanine2 exchange factor (gef) 16
112d2iima1



not modelled 99.3 32 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
113c2fpeB_



not modelled 99.3 22 PDB header:signaling protein
Chain: B: PDB Molecule:c-jun-amino-terminal kinase interacting protein
PDBTitle: conserved dimerization of the ib1 src-homology 3 domain
114d1udla_



not modelled 99.3 20 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
115d1ng2a2



not modelled 99.3 21 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
116c2kymA_



not modelled 99.3 27 PDB header:signaling protein
Chain: A: PDB Molecule:bud emergence protein 1;
PDBTitle: solution structure of the bem1p sh3-ci domain from l.elongisporus in2 complex with ste20p peptide
117c2d8hA_



not modelled 99.3 21 PDB header:unknown function
Chain: A: PDB Molecule:sh3yl1 protein;
PDBTitle: solution structure of the sh3 domain of hypothetical2 protein sh3yl1
118c2csqA_



not modelled 99.3 19 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:rim binding protein 2;
PDBTitle: solution structure of the second sh3 domain of human rim-2 binding protein 2
119c1w1fA_



not modelled 99.3 34 PDB header:sh3-domain
Chain: A: PDB Molecule:tyrosine-protein kinase lyn;
PDBTitle: sh3 domain of human lyn tyrosine kinase
120d1gbra_



not modelled 99.3 25 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain

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