Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionQ8INJ8
DateWed Feb 13 11:35:57 GMT 2013
Unique Job IDd5991504f80741ba

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2fo0A_
Top template information
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
Confidence and coverage
Confidence:100.0% Coverage: 35%
367 residues ( 35% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MVTTIKITCDGVFIQSNSYLMPTPSPSGADATVSSSLERVLKPASASASPSNSNNESDNS
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Disorder  ???















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   .........70.........80.........90.........100.........110.........120
Sequence  QTSSGSQTASSASKRSNRSVGRSHRGSIAQDTRRRYYFGSKDIYWCKQSREAAAAATLSG
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Disorder  ????????????????????????????????

















??????????
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   .........130.........140.........150.........160.........170.........180
Sequence  SGLTRSASSVTHKEASTHATHTGGQVISRARRKPILLCSSLSAAYAPPRRREFYFCDKYA
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Disorder  ???????
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   .........190.........200.........210.........220.........230.........240
Sequence  PGPARSTPTTTTTSATSAKHESSPPIDARLLNFLRCAHRKFQASKAKTELQQTKDRFLGN
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Disorder 
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   .........250.........260.........270.........280.........290.........300
Sequence  SRERTSKNGQQTSRSLPPIASSEEWFDEEAQARKTSHEKSQKPKPKPEENHKEKEAISRK
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Disorder  ??????????????
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   .........310.........320.........330.........340.........350.........360
Sequence  ASGEGDLITVEIKQGLLRKQTATTTTGQAMNSHATATQNGQTTVVGHHRGFSQPSVTVAA
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Disorder  ??

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   .........370.........380.........390.........400.........410.........420
Sequence  AAATGSTAGDPWFLQTTGHQMPPTAPLRHNKRPAPQPNAVLGAGSSGTAPGSAVGAVLLH
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Disorder  ??????










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   .........430.........440.........450.........460.........470.........480
Sequence  QQQLSQSQPHIVPPSIPPHHHHHRENNVHPIQAGAAAALHLSSHALNSHNLISSASNHSP
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Disorder 


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   .........490.........500.........510.........520.........530.........540
Sequence  KSPSQTQQQQQTTNQQQQQQQQQASHSILSTFAPAPTVAAVQPAGSQSVAGTAAAVAAVA
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Disorder  ???????????????







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   .........550.........560.........570.........580.........590.........600
Sequence  QQQQQQHLQLLANCPPGGAGLMSSSLNAAQMGMHGAERALPPKSLALSGSQHGSNMLLHT
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Disorder 



????????????????????????????????????????????????????????
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   .........610.........620.........630.........640.........650.........660
Sequence  APQPPQASQPAAVVGVSGSGSAGMSTSLHSFDINGVTAGSGVNASSAWSSGSTTAMNHAS
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Disorder  ????????????
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   .........670.........680.........690.........700.........710.........720
Sequence  LSPTALAPQQGRSRCEVKLNAMPWFHGSITRDEAEHLLQPREDGLFLVRESTNFPGDYTL
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Disorder 






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   .........730.........740.........750.........760.........770.........780
Sequence  CVCFQSKVEHYRVKYLENKLTIDDEEYFENLGQLVAHYEADADGLCTQLIKCLPKLGKQE
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   .........790.........800.........810.........820.........830.........840
Sequence  FCINSKDFVDKGWVIPEAELQLRESIGKGEFGDVMLGILRNEKVAVKMLKDEGAVQKFLA
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   .........850.........860.........870.........880.........890.........900
Sequence  EASVMTTLEHDNLVKFIGLVFTSKHLYLVTEYMSKGSLVDYLRSRGRQHITKKDQIIFAY
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   .........910.........920.........930.........940.........950.........960
Sequence  DTASGMEYLEAKKVVHRDLAARNVLISEDCVAKVSDFGLAREECYNLDVGKLPIKWTAPE
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   .........970.........980.........990.........1000.........1010.........1020
Sequence  ALKNGRFSNKSDMWSFGILLWEIYSFGRVPYPRIPLADVVKHVEVGYKMEAPEGCPPEIY
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?
???
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   .........1030.........1040.........1050..
Sequence  EMMRQAWDLNPAKRPTFAELKVKLQLLNNATA
Secondary structure 








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?????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2fo0 chain A

3D model

Region: 679 - 1047
Aligned: 367
Modelled: 369
Confidence: 100.0%
Identity: 42%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase

Phyre2

PDB 1opl chain A

3D model

Region: 678 - 1047
Aligned: 368
Modelled: 370
Confidence: 100.0%
Identity: 41%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase

Phyre2

PDB 1k9a chain B

3D model

Region: 676 - 1048
Aligned: 364
Modelled: 373
Confidence: 100.0%
Identity: 62%
PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution

Phyre2

PDB 1y57 chain A

3D model

Region: 679 - 1051
Aligned: 367
Modelled: 368
Confidence: 100.0%
Identity: 43%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor

Phyre2

PDB 2h8h chain A

3D model

Region: 679 - 1045
Aligned: 361
Modelled: 362
Confidence: 100.0%
Identity: 43%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor

Phyre2

PDB 2c0i chain A

3D model

Region: 679 - 1051
Aligned: 357
Modelled: 373
Confidence: 100.0%
Identity: 42%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983

Phyre2

PDB 4fl2 chain A

3D model

Region: 682 - 1047
Aligned: 362
Modelled: 366
Confidence: 100.0%
Identity: 40%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase syk;
PDBTitle: structural and biophysical characterization of the syk activation2 switch

Phyre2

PDB 2ozo chain A

3D model

Region: 680 - 1052
Aligned: 362
Modelled: 373
Confidence: 100.0%
Identity: 35%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70

Phyre2

PDB 2j0k chain B

3D model

Region: 780 - 1048
Aligned: 257
Modelled: 269
Confidence: 100.0%
Identity: 37%
PDB header:transferase
Chain: B: PDB Molecule:focal adhesion kinase 1;
PDBTitle: crystal structure of a fragment of focal adhesion kinase2 containing the ferm and kinase domains.

Phyre2

PDB 3cbl chain A

3D model

Region: 670 - 1048
Aligned: 343
Modelled: 349
Confidence: 100.0%
Identity: 39%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: crystal structure of human feline sarcoma viral oncogene homologue (v-2 fes) in complex with staurosporine and a consensus peptide

Phyre2

PDB 3nyo chain B

3D model

Region: 791 - 1043
Aligned: 252
Modelled: 253
Confidence: 100.0%
Identity: 24%
PDB header:transferase
Chain: B: PDB Molecule:g protein-coupled receptor kinase 6;
PDBTitle: crystal structure of g protein-coupled receptor kinase 6 in complex2 with amp

Phyre2

PDB 3pfq chain A

3D model

Region: 793 - 1041
Aligned: 245
Modelled: 249
Confidence: 100.0%
Identity: 26%
PDB header:transferase
Chain: A: PDB Molecule:protein kinase c beta type;
PDBTitle: crystal structure and allosteric activation of protein kinase c beta2 ii

Phyre2

PDB 2acx chain B

3D model

Region: 791 - 1041
Aligned: 248
Modelled: 251
Confidence: 100.0%
Identity: 24%
PDB header:transferase
Chain: B: PDB Molecule:g protein-coupled receptor kinase 6;
PDBTitle: crystal structure of g protein coupled receptor kinase 6 bound to2 amppnp

Phyre2

PDB 3qa8 chain H

3D model

Region: 801 - 1037
Aligned: 236
Modelled: 237
Confidence: 100.0%
Identity: 23%
PDB header:immune system, signaling protein
Chain: H: PDB Molecule:mgc80376 protein;
PDBTitle: crystal structure of inhibitor of kappa b kinase beta

Phyre2

PDB 1ym7 chain C

3D model

Region: 798 - 1043
Aligned: 242
Modelled: 246
Confidence: 100.0%
Identity: 24%
PDB header:transferase
Chain: C: PDB Molecule:beta-adrenergic receptor kinase 1;
PDBTitle: g protein-coupled receptor kinase 2 (grk2)

Phyre2

PDB 3c4w chain B

3D model

Region: 794 - 1043
Aligned: 248
Modelled: 250
Confidence: 100.0%
Identity: 22%
PDB header:transferase
Chain: B: PDB Molecule:rhodopsin kinase;
PDBTitle: crystal structure of g protein coupled receptor kinase 1 bound to atp2 and magnesium chloride at 2.7a

Phyre2

PDB 3qa8 chain A

3D model

Region: 801 - 1036
Aligned: 235
Modelled: 236
Confidence: 100.0%
Identity: 24%
PDB header:immune system, signaling protein
Chain: A: PDB Molecule:mgc80376 protein;
PDBTitle: crystal structure of inhibitor of kappa b kinase beta

Phyre2

PDB 1qcf chain A domain 3

3D model

Region: 783 - 1051
Aligned: 268
Modelled: 269
Confidence: 100.0%
Identity: 44%
Fold: Protein kinase-like (PK-like)
Superfamily: Protein kinase-like (PK-like)
Family: Protein kinases, catalytic subunit

Phyre2

PDB 3c4y chain A

3D model

Region: 793 - 1041
Aligned: 247
Modelled: 249
Confidence: 100.0%
Identity: 23%
PDB header:transferase
Chain: A: PDB Molecule:rhodopsin kinase;
PDBTitle: crystal structure of apo form of g protein coupled receptor kinase 12 at 7.51a

Phyre2

PDB 3zzw chain A

3D model

Region: 794 - 1047
Aligned: 252
Modelled: 254
Confidence: 100.0%
Identity: 36%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase transmembrane receptor ror2;
PDBTitle: crystal structure of the kinase domain of ror2

Phyre2
1

c2fo0A_
2

c1oplA_
3

c1k9aB_
4

c1y57A_
5

c2h8hA_
6

c2c0iA_
7

c4fl2A_
8

c2ozoA_
9

c2j0kB_
10

c3cblA_
11

c3nyoB_
12

c3pfqA_
13

c2acxB_
14

c3qa8H_
15

c1ym7C_
16

c3c4wB_
17

c3qa8A_
18

d1qcfa3
19

c3c4yA_
20

c3zzwA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2fo0A_



100.0 42 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
2c1oplA_



100.0 41 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
3c1k9aB_



100.0 62 PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
4c1y57A_



100.0 43 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
5c2h8hA_



100.0 43 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor
6c2c0iA_



100.0 42 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983
7c4fl2A_



100.0 40 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase syk;
PDBTitle: structural and biophysical characterization of the syk activation2 switch
8c2ozoA_



100.0 35 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70
9c2j0kB_



100.0 37 PDB header:transferase
Chain: B: PDB Molecule:focal adhesion kinase 1;
PDBTitle: crystal structure of a fragment of focal adhesion kinase2 containing the ferm and kinase domains.
10c3cblA_



100.0 39 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: crystal structure of human feline sarcoma viral oncogene homologue (v-2 fes) in complex with staurosporine and a consensus peptide
11c3nyoB_



100.0 24 PDB header:transferase
Chain: B: PDB Molecule:g protein-coupled receptor kinase 6;
PDBTitle: crystal structure of g protein-coupled receptor kinase 6 in complex2 with amp
12c3pfqA_



100.0 26 PDB header:transferase
Chain: A: PDB Molecule:protein kinase c beta type;
PDBTitle: crystal structure and allosteric activation of protein kinase c beta2 ii
13c2acxB_



100.0 24 PDB header:transferase
Chain: B: PDB Molecule:g protein-coupled receptor kinase 6;
PDBTitle: crystal structure of g protein coupled receptor kinase 6 bound to2 amppnp
14c3qa8H_



100.0 23 PDB header:immune system, signaling protein
Chain: H: PDB Molecule:mgc80376 protein;
PDBTitle: crystal structure of inhibitor of kappa b kinase beta
15c1ym7C_



100.0 24 PDB header:transferase
Chain: C: PDB Molecule:beta-adrenergic receptor kinase 1;
PDBTitle: g protein-coupled receptor kinase 2 (grk2)
16c3c4wB_



100.0 22 PDB header:transferase
Chain: B: PDB Molecule:rhodopsin kinase;
PDBTitle: crystal structure of g protein coupled receptor kinase 1 bound to atp2 and magnesium chloride at 2.7a
17c3qa8A_



100.0 24 PDB header:immune system, signaling protein
Chain: A: PDB Molecule:mgc80376 protein;
PDBTitle: crystal structure of inhibitor of kappa b kinase beta
18d1qcfa3



100.0 44 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
19c3c4yA_



100.0 23 PDB header:transferase
Chain: A: PDB Molecule:rhodopsin kinase;
PDBTitle: crystal structure of apo form of g protein coupled receptor kinase 12 at 7.51a
20c3zzwA_



100.0 36 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase transmembrane receptor ror2;
PDBTitle: crystal structure of the kinase domain of ror2
21d1opja_



not modelled 100.0 43 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
22c3soaA_



not modelled 100.0 24 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:calcium/calmodulin-dependent protein kinase type ii subunit
PDBTitle: full-length human camkii
23d1qpca_



not modelled 100.0 43 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
24c1koaA_



not modelled 100.0 21 PDB header:kinase
Chain: A: PDB Molecule:twitchin;
PDBTitle: twitchin kinase fragment (c.elegans), autoregulated protein2 kinase and immunoglobulin domains
25c3ckxA_



not modelled 100.0 28 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase 24;
PDBTitle: crystal structure of sterile 20-like kinase 3 (mst3, stk24)2 in complex with staurosporine
26c2ivsA_



not modelled 100.0 40 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase receptor
PDBTitle: crystal structure of non-phosphorylated ret tyrosine kinase2 domain
27c3tkuB_



not modelled 100.0 19 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:serine/threonine-protein kinase mrck beta;
PDBTitle: mrck beta in complex with fasudil
28c1lufA_



not modelled 100.0 37 PDB header:transferase
Chain: A: PDB Molecule:muscle-specific tyrosine kinase receptor musk;
PDBTitle: crystal structure of the musk tyrosine kinase: insights2 into receptor autoregulation
29d1lufa_



not modelled 100.0 37 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
30c3g0eA_



not modelled 100.0 37 PDB header:transferase
Chain: A: PDB Molecule:mast/stem cell growth factor receptor;
PDBTitle: kit kinase domain in complex with sunitinib
31d2j4za1



not modelled 100.0 22 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
32c2vwiC_



not modelled 100.0 27 PDB header:transferase
Chain: C: PDB Molecule:serine/threonine-protein kinase osr1;
PDBTitle: structure of the osr1 kinase, a hypertension drug target
33c3q5iA_



not modelled 100.0 27 PDB header:transferase
Chain: A: PDB Molecule:protein kinase;
PDBTitle: crystal structure of pbanka_031420
34c2pvfA_



not modelled 100.0 42 PDB header:transferase
Chain: A: PDB Molecule:fibroblast growth factor receptor 2;
PDBTitle: crystal structure of tyrosine phosphorylated activated fgf receptor 22 (fgfr2) kinase domain in complex with atp analog and substrate3 peptide
35c2c30A_



not modelled 100.0 24 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase pak 6;
PDBTitle: crystal structure of the human p21-activated kinase 6
36c4fijA_



not modelled 100.0 25 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase pak 4;
PDBTitle: catalytic domain of human pak4
37d1u59a_



not modelled 100.0 36 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
38c3dpkA_



not modelled 100.0 38 PDB header:transferase
Chain: A: PDB Molecule:macrophage colony-stimulating factor 1 receptor;
PDBTitle: cfms tyrosine kinase in complex with a pyridopyrimidinone2 inhibitor
39c2psqA_



not modelled 100.0 42 PDB header:transferase
Chain: A: PDB Molecule:fibroblast growth factor receptor 2;
PDBTitle: crystal structure of unphosphorylated unactivated wild type2 fgf receptor 2 (fgfr2) kinase domain
40d2psqa1



not modelled 100.0 42 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
41c4dn5A_



not modelled 100.0 21 PDB header:transferase
Chain: A: PDB Molecule:mitogen-activated protein kinase kinase kinase 14;
PDBTitle: crystal structure of nf-kb-inducing kinase (nik)
42c2bujA_



not modelled 100.0 19 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase 16;
PDBTitle: crystal structure of the human serine-threonine kinase 162 in complex with staurosporine
43c4fieB_



not modelled 100.0 25 PDB header:transferase
Chain: B: PDB Molecule:serine/threonine-protein kinase pak 4;
PDBTitle: full-length human pak4
44d1k2pa_



not modelled 100.0 37 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
45c4aojA_



not modelled 100.0 37 PDB header:transferase
Chain: A: PDB Molecule:high affinity nerve growth factor receptor;
PDBTitle: human trka in complex with the inhibitor az-23
46c2jamB_



not modelled 100.0 25 PDB header:transferase
Chain: B: PDB Molecule:calcium/calmodulin-dependent protein kinase type
PDBTitle: crystal structure of human calmodulin-dependent protein2 kinase i g
47d3bu3a1



not modelled 100.0 40 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
48c3lxkA_



not modelled 100.0 36 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase jak3;
PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6
49c4eutA_



not modelled 100.0 23 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:serine/threonine-protein kinase tbk1;
PDBTitle: structure of bx-795 complexed with unphosphorylated human tbk1 kinase-2 uld domain
50c3lijA_



not modelled 100.0 25 PDB header:transferase
Chain: A: PDB Molecule:calcium/calmodulin dependent protein kinase with
PDBTitle: crystal structure of full length cpcdpk3 (cgd5_820) in2 complex with ca2+ and amppnp
51d1yhwa1



not modelled 100.0 23 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
52c2a1aB_



not modelled 100.0 21 PDB header:protein synthesis/transferase
Chain: B: PDB Molecule:interferon-induced, double-stranded rna-activated protein
PDBTitle: pkr kinase domain-eif2alpha complex
53c2wtkC_



not modelled 100.0 23 PDB header:transferase/metal-binding protein
Chain: C: PDB Molecule:serine/threonine-protein kinase 11;
PDBTitle: structure of the heterotrimeric lkb1-stradalpha-mo25alpha2 complex
54c3d9vA_



not modelled 100.0 22 PDB header:transferase
Chain: A: PDB Molecule:rho-associated protein kinase 1;
PDBTitle: crystal structure of rock i bound to h-1152p a di-2 methylated variant of fasudil
55d1p4oa_



not modelled 100.0 35 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
56d1t46a_



not modelled 100.0 34 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
57c3fbvL_



not modelled 100.0 28 PDB header:transferase, hydrolase
Chain: L: PDB Molecule:serine/threonine-protein kinase/endoribonuclease ire1;
PDBTitle: crystal structure of the oligomer formed by the kinase-ribonuclease2 domain of ire1
58c3plsA_



not modelled 100.0 40 PDB header:transferase
Chain: A: PDB Molecule:macrophage-stimulating protein receptor;
PDBTitle: ron in complex with ligand amp-pnp
59c2bmcD_



not modelled 100.0 23 PDB header:transferase
Chain: D: PDB Molecule:serine threonine-protein kinase 6;
PDBTitle: aurora-2 t287d t288d complexed with pha-680632
60c3lvpD_



not modelled 100.0 38 PDB header:transferase
Chain: D: PDB Molecule:insulin-like growth factor 1 receptor;
PDBTitle: crystal structure of bisphosphorylated igf1-r kinase domain (2p) in2 complex with a bis-azaindole inhibitor
61c4ebwA_



not modelled 100.0 39 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:focal adhesion kinase 1;
PDBTitle: structure of focal adhesion kinase catalytic domain in complex with2 novel allosteric inhibitor
62c3kulB_



not modelled 100.0 41 PDB header:transferase
Chain: B: PDB Molecule:ephrin type-a receptor 8;
PDBTitle: kinase domain of human ephrin type-a receptor 8 (epha8)
63c2pziA_



not modelled 100.0 21 PDB header:transferase
Chain: A: PDB Molecule:probable serine/threonine-protein kinase pkng;
PDBTitle: crystal structure of protein kinase pkng from mycobacterium2 tuberculosis in complex with tetrahydrobenzothiophene ax20017
64d1fmka3



not modelled 100.0 45 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
65d1fgka_



not modelled 100.0 41 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
66c3l9pA_



not modelled 100.0 38 PDB header:transferase
Chain: A: PDB Molecule:anaplastic lymphoma kinase;
PDBTitle: crystal structure of the anaplastic lymphoma kinase catalytic domain
67d1phka_



not modelled 100.0 22 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
68c2y7jB_



not modelled 100.0 21 PDB header:transferase
Chain: B: PDB Molecule:phosphorylase b kinase gamma catalytic chain,
PDBTitle: structure of human phosphorylase kinase, gamma 2
69c3dfaA_



not modelled 100.0 27 PDB header:transferase
Chain: A: PDB Molecule:calcium-dependent protein kinase cgd3_920;
PDBTitle: crystal structure of kinase domain of calcium-dependent protein kinase2 cgd3_920 from cryptosporidium parvum
70c2a27B_



not modelled 100.0 21 PDB header:transferase
Chain: B: PDB Molecule:death-associated protein kinase 2;
PDBTitle: human drp-1 kinase, w305s s308a d40 mutant, crystal form with 82 monomers in the asymmetric unit
71c3p23B_



not modelled 100.0 24 PDB header:hydrolase, transferase
Chain: B: PDB Molecule:serine/threonine-protein kinase/endoribonuclease ire1;
PDBTitle: crystal structure of the human kinase and rnase domains in complex2 with adp
72d1uwha_



not modelled 100.0 32 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
73c3hztA_



not modelled 100.0 26 PDB header:transferase
Chain: A: PDB Molecule:calcium-dependent protein kinase 3;
PDBTitle: crystal structure of toxoplasma gondii cdpk3, tgme49_105860
74c2wqmA_



not modelled 100.0 24 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase nek7;
PDBTitle: structure of apo human nek7
75d1mp8a_



not modelled 100.0 37 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
76c2j51A_



not modelled 100.0 24 PDB header:transferase
Chain: A: PDB Molecule:ste20-like serine/threonine-protein kinase;
PDBTitle: crystal structure of human ste20-like kinase bound to 5-2 amino-3-((4-(aminosulfonyl)phenyl)amino)-n-(2,6-3 difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide
77c3d4qA_



not modelled 100.0 34 PDB header:transferase
Chain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase;
PDBTitle: pyrazole-based inhibitors of b-raf kinase
78d1sm2a_



not modelled 100.0 38 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
79c3vw6B_



not modelled 100.0 27 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:mitogen-activated protein kinase kinase kinase 5;
PDBTitle: crystal structure of human apoptosis signal-regulating kinase 1 (ask1)2 with imidazopyridine inhibitor
80c2qg5D_



not modelled 100.0 24 PDB header:transferase
Chain: D: PDB Molecule:calcium/calmodulin-dependent protein kinase;
PDBTitle: cryptosporidium parvum calcium dependent protein kinase cgd7_1840
81c1yvjA_



not modelled 100.0 34 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase jak3;
PDBTitle: crystal structure of the jak3 kinase domain in complex with2 a staurosporine analogue
82d1o6ya_



not modelled 100.0 28 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
83c1xjdA_



not modelled 100.0 26 PDB header:transferase
Chain: A: PDB Molecule:protein kinase c, theta type;
PDBTitle: crystal structure of pkc-theta complexed with staurosporine2 at 2a resolution
84d1xjda_



not modelled 100.0 26 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
85c1mruB_



not modelled 100.0 27 PDB header:transferase
Chain: B: PDB Molecule:probable serine/threonine-protein kinase pknb;
PDBTitle: intracellular ser/thr protein kinase domain of2 mycobacterium tuberculosis pknb.
86c2clqA_



not modelled 100.0 26 PDB header:transferase
Chain: A: PDB Molecule:mitogen-activated protein kinase kinase kinase 5;
PDBTitle: structure of mitogen-activated protein kinase kinase kinase2 5
87c2vd5A_



not modelled 100.0 20 PDB header:transferase
Chain: A: PDB Molecule:dmpk protein;
PDBTitle: structure of human myotonic dystrophy protein kinase in2 complex with the bisindoylmaleide inhibitor bim viii
88d1jksa_



not modelled 100.0 21 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
89d2jfla1



not modelled 100.0 23 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
90c2bdwB_



not modelled 100.0 25 PDB header:transferase
Chain: B: PDB Molecule:hypothetical protein k11e8.1d;
PDBTitle: crystal structure of the auto-inhibited kinase domain of2 calcium/calmodulin activated kinase ii
91d1jpaa_



not modelled 100.0 39 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
92c3comB_



not modelled 100.0 28 PDB header:transferase
Chain: B: PDB Molecule:serine/threonine-protein kinase 4;
PDBTitle: crystal structure of mst1 kinase
93c2wtkB_



not modelled 100.0 24 PDB header:transferase/metal-binding protein
Chain: B: PDB Molecule:ste20-related kinase adapter protein alpha;
PDBTitle: structure of the heterotrimeric lkb1-stradalpha-mo25alpha2 complex
94d1rjba_



not modelled 100.0 44 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
95c2cgvA_



not modelled 100.0 28 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase chk1;
PDBTitle: identification of chemically diverse chk1 inhibitors by2 receptor-based virtual screening
96c2ya9A_



not modelled 100.0 22 PDB header:transferase
Chain: A: PDB Molecule:death-associated protein kinase 2;
PDBTitle: crystal structure of the autoinhibited form of mouse dapk2
97c3v5qB_



not modelled 100.0 34 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:nt-3 growth factor receptor;
PDBTitle: discovery of a selective trk inhibitor with efficacy in rodent cancer2 tumor models
98d1xbba_



not modelled 100.0 39 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
99c3eygA_



not modelled 100.0 33 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase;
PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes
100c3cc6A_



not modelled 100.0 35 PDB header:transferase
Chain: A: PDB Molecule:protein tyrosine kinase 2 beta;
PDBTitle: crystal structure of kinase domain of protein tyrosine kinase 2 beta2 (ptk2b)
101d1fvra_



not modelled 100.0 39 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
102c3fupB_



not modelled 100.0 34 PDB header:transferase
Chain: B: PDB Molecule:tyrosine-protein kinase jak2;
PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes
103d1mqba_



not modelled 100.0 40 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
104d1o6la_



not modelled 100.0 24 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
105d1ckia_



not modelled 100.0 20 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
106c3lxnA_



not modelled 100.0 36 PDB header:transferase
Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2;
PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6
107c2r7bA_



not modelled 100.0 25 PDB header:signaling protein, transferase
Chain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1;
PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor
108d1uu3a_



not modelled 100.0 24 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
109c4eqmE_



not modelled 100.0 25 PDB header:transferase
Chain: E: PDB Molecule:protein kinase;
PDBTitle: structural analysis of staphylococcus aureus serine/threonine kinase2 pknb
110d1koaa2



not modelled 100.0 21 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
111c2vrxB_



not modelled 100.0 21 PDB header:cell cycle/transferase
Chain: B: PDB Molecule:serine/threonine-protein kinase 12-a;
PDBTitle: structure of aurora b kinase in complex with zm447439
112c2w1iB_



not modelled 100.0 35 PDB header:transferase
Chain: B: PDB Molecule:jak2;
PDBTitle: structure determination of aurora kinase in complex with2 inhibitor
113d1koba_



not modelled 100.0 21 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
114c2zv2A_



not modelled 100.0 24 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:calcium/calmodulin-dependent protein kinase kinase 2;
PDBTitle: crystal structure of human calcium/calmodulin-dependent protein kinase2 kinase 2, beta, camkk2 kinase domain in complex with sto-609
115c2chlA_



not modelled 100.0 21 PDB header:transferase
Chain: A: PDB Molecule:casein kinase i isoform gamma-3;
PDBTitle: structure of casein kinase 1 gamma 3
116d1nvra_



not modelled 100.0 28 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
117c2qobA_



not modelled 100.0 40 PDB header:transferase
Chain: A: PDB Molecule:ephrin receptor;
PDBTitle: human epha3 kinase domain, base structure
118d1xkka_



not modelled 100.0 34 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
119c1xkkA_



not modelled 100.0 34 PDB header:transferase
Chain: A: PDB Molecule:epidermal growth factor receptor;
PDBTitle: egfr kinase domain complexed with a quinazoline inhibitor-2 gw572016
120c2vz6A_



not modelled 100.0 25 PDB header:transferase
Chain: A: PDB Molecule:calcium calmodulin dependent protein kinase type ii alpha
PDBTitle: structure of human calcium calmodulin dependent protein2 kinase type ii alpha (camk2a) in complex with indirubin3 e804

Binding site prediction 

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