Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP00528
DateTue Jan 22 11:25:29 GMT 2013
Unique Job ID3b1e78d5412abaad

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1y57A_
Top template information
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
Confidence and coverage
Confidence:100.0% Coverage: 81%
449 residues ( 81% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MGNKCCSKRQDQELALAYPTGGYKKSDYTFGQTHINSSGGGNMGGVLGQKHNNGGSLDSR
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Disorder  ????????????
??
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??




???
?
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   .........70.........80.........90.........100.........110.........120
Sequence  YTPDPNHRGPLKIGGKGGVDIIRPRTTPTGVPGVVLKRVVVALYDYKSRDESDLSFMKGD
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Disorder  ??????????????????????????????????
?










?
??????




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   .........130.........140.........150.........160.........170.........180
Sequence  RMEVIDDTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFENVLRKEADKLLLAEE
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??
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   .........190.........200.........210.........220.........230.........240
Sequence  NPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIATNQTFPSLQAL
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??









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   .........250.........260.........270.........280.........290.........300
Sequence  VMAYSKNALGLCHILSRPCPKPQPQMWDLGPELRDKYEIPRSEIQLLRKLGRGNFGEVFY
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   .........310.........320.........330.........340.........350.........360
Sequence  GKWRNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMS
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?
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   .........370.........380.........390.........400.........410.........420
Sequence  KGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKI
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   .........430.........440.........450.........460.........470.........480
Sequence  CDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVP
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   .........490.........500.........510.........520.........530.........540
Sequence  YPGMHSREVIENIERGFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTFEFLNHYFESFS
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?
???

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   .........550..
Sequence  VTSEVPYREVQD
Secondary structure 






SS confidence 











Disorder 


?????????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1y57 chain A

3D model

Region: 98 - 552
Aligned: 449
Modelled: 455
Confidence: 100.0%
Identity: 55%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor

Phyre2

PDB 2fo0 chain A

3D model

Region: 86 - 544
Aligned: 449
Modelled: 459
Confidence: 100.0%
Identity: 41%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase

Phyre2

PDB 1opl chain A

3D model

Region: 97 - 544
Aligned: 438
Modelled: 448
Confidence: 100.0%
Identity: 41%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase

Phyre2

PDB 2h8h chain A

3D model

Region: 100 - 546
Aligned: 441
Modelled: 447
Confidence: 100.0%
Identity: 55%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor

Phyre2

PDB 2c0i chain A

3D model

Region: 97 - 548
Aligned: 431
Modelled: 439
Confidence: 100.0%
Identity: 49%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983

Phyre2

PDB 1k9a chain B

3D model

Region: 92 - 543
Aligned: 429
Modelled: 452
Confidence: 100.0%
Identity: 38%
PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution

Phyre2

PDB 2ozo chain A

3D model

Region: 154 - 546
Aligned: 372
Modelled: 393
Confidence: 100.0%
Identity: 38%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70

Phyre2

PDB 4fl2 chain A

3D model

Region: 158 - 540
Aligned: 372
Modelled: 383
Confidence: 100.0%
Identity: 37%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase syk;
PDBTitle: structural and biophysical characterization of the syk activation2 switch

Phyre2

PDB 3cbl chain A

3D model

Region: 146 - 539
Aligned: 346
Modelled: 379
Confidence: 100.0%
Identity: 43%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: crystal structure of human feline sarcoma viral oncogene homologue (v-2 fes) in complex with staurosporine and a consensus peptide

Phyre2

PDB 2j0k chain B

3D model

Region: 199 - 546
Aligned: 330
Modelled: 348
Confidence: 100.0%
Identity: 32%
PDB header:transferase
Chain: B: PDB Molecule:focal adhesion kinase 1;
PDBTitle: crystal structure of a fragment of focal adhesion kinase2 containing the ferm and kinase domains.

Phyre2

PDB 1qcf chain A domain 3

3D model

Region: 267 - 546
Aligned: 277
Modelled: 280
Confidence: 100.0%
Identity: 50%
Fold: Protein kinase-like (PK-like)
Superfamily: Protein kinase-like (PK-like)
Family: Protein kinases, catalytic subunit

Phyre2

PDB 1opj chain A

3D model

Region: 266 - 544
Aligned: 277
Modelled: 279
Confidence: 100.0%
Identity: 48%
Fold: Protein kinase-like (PK-like)
Superfamily: Protein kinase-like (PK-like)
Family: Protein kinases, catalytic subunit

Phyre2

PDB 1qpc chain A

3D model

Region: 271 - 543
Aligned: 269
Modelled: 273
Confidence: 100.0%
Identity: 51%
Fold: Protein kinase-like (PK-like)
Superfamily: Protein kinase-like (PK-like)
Family: Protein kinases, catalytic subunit

Phyre2

PDB 3zzw chain A

3D model

Region: 278 - 539
Aligned: 258
Modelled: 262
Confidence: 100.0%
Identity: 37%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase transmembrane receptor ror2;
PDBTitle: crystal structure of the kinase domain of ror2

Phyre2

PDB 3qa8 chain H

3D model

Region: 285 - 529
Aligned: 242
Modelled: 245
Confidence: 100.0%
Identity: 23%
PDB header:immune system, signaling protein
Chain: H: PDB Molecule:mgc80376 protein;
PDBTitle: crystal structure of inhibitor of kappa b kinase beta

Phyre2

PDB 1k2p chain A

3D model

Region: 279 - 539
Aligned: 258
Modelled: 261
Confidence: 100.0%
Identity: 43%
Fold: Protein kinase-like (PK-like)
Superfamily: Protein kinase-like (PK-like)
Family: Protein kinases, catalytic subunit

Phyre2

PDB 3pfq chain A

3D model

Region: 274 - 552
Aligned: 270
Modelled: 279
Confidence: 100.0%
Identity: 23%
PDB header:transferase
Chain: A: PDB Molecule:protein kinase c beta type;
PDBTitle: crystal structure and allosteric activation of protein kinase c beta2 ii

Phyre2

PDB 3nyo chain B

3D model

Region: 275 - 534
Aligned: 255
Modelled: 260
Confidence: 100.0%
Identity: 24%
PDB header:transferase
Chain: B: PDB Molecule:g protein-coupled receptor kinase 6;
PDBTitle: crystal structure of g protein-coupled receptor kinase 6 in complex2 with amp

Phyre2

PDB 2ivs chain A

3D model

Region: 274 - 542
Aligned: 267
Modelled: 269
Confidence: 100.0%
Identity: 41%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase receptor
PDBTitle: crystal structure of non-phosphorylated ret tyrosine kinase2 domain

Phyre2

PDB 1u59 chain A

3D model

Region: 275 - 546
Aligned: 268
Modelled: 272
Confidence: 100.0%
Identity: 38%
Fold: Protein kinase-like (PK-like)
Superfamily: Protein kinase-like (PK-like)
Family: Protein kinases, catalytic subunit

Phyre2
1

c1y57A_
2

c2fo0A_
3

c1oplA_
4

c2h8hA_
5

c2c0iA_
6

c1k9aB_
7

c2ozoA_
8

c4fl2A_
9

c3cblA_
10

c2j0kB_
11

d1qcfa3
12

d1opja_
13

d1qpca_
14

c3zzwA_
15

c3qa8H_
16

d1k2pa_
17

c3pfqA_
18

c3nyoB_
19

c2ivsA_
20

d1u59a_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1y57A_



100.0 55 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
2c2fo0A_



100.0 41 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
3c1oplA_



100.0 41 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
4c2h8hA_



100.0 55 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor
5c2c0iA_



100.0 49 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983
6c1k9aB_



100.0 38 PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
7c2ozoA_



100.0 38 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70
8c4fl2A_



100.0 37 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase syk;
PDBTitle: structural and biophysical characterization of the syk activation2 switch
9c3cblA_



100.0 43 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: crystal structure of human feline sarcoma viral oncogene homologue (v-2 fes) in complex with staurosporine and a consensus peptide
10c2j0kB_



100.0 32 PDB header:transferase
Chain: B: PDB Molecule:focal adhesion kinase 1;
PDBTitle: crystal structure of a fragment of focal adhesion kinase2 containing the ferm and kinase domains.
11d1qcfa3



100.0 50 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
12d1opja_



100.0 48 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
13d1qpca_



100.0 51 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
14c3zzwA_



100.0 37 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase transmembrane receptor ror2;
PDBTitle: crystal structure of the kinase domain of ror2
15c3qa8H_



100.0 23 PDB header:immune system, signaling protein
Chain: H: PDB Molecule:mgc80376 protein;
PDBTitle: crystal structure of inhibitor of kappa b kinase beta
16d1k2pa_



100.0 43 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
17c3pfqA_



100.0 23 PDB header:transferase
Chain: A: PDB Molecule:protein kinase c beta type;
PDBTitle: crystal structure and allosteric activation of protein kinase c beta2 ii
18c3nyoB_



100.0 24 PDB header:transferase
Chain: B: PDB Molecule:g protein-coupled receptor kinase 6;
PDBTitle: crystal structure of g protein-coupled receptor kinase 6 in complex2 with amp
19c2ivsA_



100.0 41 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase receptor
PDBTitle: crystal structure of non-phosphorylated ret tyrosine kinase2 domain
20d1u59a_



100.0 38 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
21c3g0eA_



not modelled 100.0 43 PDB header:transferase
Chain: A: PDB Molecule:mast/stem cell growth factor receptor;
PDBTitle: kit kinase domain in complex with sunitinib
22c2acxB_



not modelled 100.0 25 PDB header:transferase
Chain: B: PDB Molecule:g protein-coupled receptor kinase 6;
PDBTitle: crystal structure of g protein coupled receptor kinase 6 bound to2 amppnp
23c1lufA_



not modelled 100.0 40 PDB header:transferase
Chain: A: PDB Molecule:muscle-specific tyrosine kinase receptor musk;
PDBTitle: crystal structure of the musk tyrosine kinase: insights2 into receptor autoregulation
24d1lufa_



not modelled 100.0 40 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
25c3ckxA_



not modelled 100.0 30 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase 24;
PDBTitle: crystal structure of sterile 20-like kinase 3 (mst3, stk24)2 in complex with staurosporine
26c3qa8A_



not modelled 100.0 24 PDB header:immune system, signaling protein
Chain: A: PDB Molecule:mgc80376 protein;
PDBTitle: crystal structure of inhibitor of kappa b kinase beta
27d1fmka3



not modelled 100.0 58 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
28c2vwiC_



not modelled 100.0 28 PDB header:transferase
Chain: C: PDB Molecule:serine/threonine-protein kinase osr1;
PDBTitle: structure of the osr1 kinase, a hypertension drug target
29c2pvfA_



not modelled 100.0 42 PDB header:transferase
Chain: A: PDB Molecule:fibroblast growth factor receptor 2;
PDBTitle: crystal structure of tyrosine phosphorylated activated fgf receptor 22 (fgfr2) kinase domain in complex with atp analog and substrate3 peptide
30c2c30A_



not modelled 100.0 24 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase pak 6;
PDBTitle: crystal structure of the human p21-activated kinase 6
31c1koaA_



not modelled 100.0 21 PDB header:kinase
Chain: A: PDB Molecule:twitchin;
PDBTitle: twitchin kinase fragment (c.elegans), autoregulated protein2 kinase and immunoglobulin domains
32c3dpkA_



not modelled 100.0 41 PDB header:transferase
Chain: A: PDB Molecule:macrophage colony-stimulating factor 1 receptor;
PDBTitle: cfms tyrosine kinase in complex with a pyridopyrimidinone2 inhibitor
33c3c4wB_



not modelled 100.0 23 PDB header:transferase
Chain: B: PDB Molecule:rhodopsin kinase;
PDBTitle: crystal structure of g protein coupled receptor kinase 1 bound to atp2 and magnesium chloride at 2.7a
34d2psqa1



not modelled 100.0 42 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
35c2psqA_



not modelled 100.0 42 PDB header:transferase
Chain: A: PDB Molecule:fibroblast growth factor receptor 2;
PDBTitle: crystal structure of unphosphorylated unactivated wild type2 fgf receptor 2 (fgfr2) kinase domain
36c3c4yA_



not modelled 100.0 24 PDB header:transferase
Chain: A: PDB Molecule:rhodopsin kinase;
PDBTitle: crystal structure of apo form of g protein coupled receptor kinase 12 at 7.51a
37c3q5iA_



not modelled 100.0 24 PDB header:transferase
Chain: A: PDB Molecule:protein kinase;
PDBTitle: crystal structure of pbanka_031420
38d3bu3a1



not modelled 100.0 36 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
39c1ym7C_



not modelled 100.0 20 PDB header:transferase
Chain: C: PDB Molecule:beta-adrenergic receptor kinase 1;
PDBTitle: g protein-coupled receptor kinase 2 (grk2)
40c3soaA_



not modelled 100.0 20 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:calcium/calmodulin-dependent protein kinase type ii subunit
PDBTitle: full-length human camkii
41c4fijA_



not modelled 100.0 24 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase pak 4;
PDBTitle: catalytic domain of human pak4
42c3tkuB_



not modelled 100.0 23 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:serine/threonine-protein kinase mrck beta;
PDBTitle: mrck beta in complex with fasudil
43d2j4za1



not modelled 100.0 24 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
44c3kulB_



not modelled 100.0 41 PDB header:transferase
Chain: B: PDB Molecule:ephrin type-a receptor 8;
PDBTitle: kinase domain of human ephrin type-a receptor 8 (epha8)
45c4aojA_



not modelled 100.0 38 PDB header:transferase
Chain: A: PDB Molecule:high affinity nerve growth factor receptor;
PDBTitle: human trka in complex with the inhibitor az-23
46d1t46a_



not modelled 100.0 41 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
47c4fieB_



not modelled 100.0 24 PDB header:transferase
Chain: B: PDB Molecule:serine/threonine-protein kinase pak 4;
PDBTitle: full-length human pak4
48c3lxkA_



not modelled 100.0 34 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase jak3;
PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6
49c4dn5A_



not modelled 100.0 22 PDB header:transferase
Chain: A: PDB Molecule:mitogen-activated protein kinase kinase kinase 14;
PDBTitle: crystal structure of nf-kb-inducing kinase (nik)
50c3lvpD_



not modelled 100.0 37 PDB header:transferase
Chain: D: PDB Molecule:insulin-like growth factor 1 receptor;
PDBTitle: crystal structure of bisphosphorylated igf1-r kinase domain (2p) in2 complex with a bis-azaindole inhibitor
51d1sm2a_



not modelled 100.0 45 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
52d1yhwa1



not modelled 100.0 23 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
53d1p4oa_



not modelled 100.0 36 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
54c4ebwA_



not modelled 100.0 39 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:focal adhesion kinase 1;
PDBTitle: structure of focal adhesion kinase catalytic domain in complex with2 novel allosteric inhibitor
55d1fgka_



not modelled 100.0 41 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
56c3plsA_



not modelled 100.0 40 PDB header:transferase
Chain: A: PDB Molecule:macrophage-stimulating protein receptor;
PDBTitle: ron in complex with ligand amp-pnp
57c3sxrA_



not modelled 100.0 47 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:cytoplasmic tyrosine-protein kinase bmx;
PDBTitle: crystal structure of bmx non-receptor tyrosine kinase complex with2 dasatinib
58c2jamB_



not modelled 100.0 27 PDB header:transferase
Chain: B: PDB Molecule:calcium/calmodulin-dependent protein kinase type
PDBTitle: crystal structure of human calmodulin-dependent protein2 kinase i g
59c3l9pA_



not modelled 100.0 43 PDB header:transferase
Chain: A: PDB Molecule:anaplastic lymphoma kinase;
PDBTitle: crystal structure of the anaplastic lymphoma kinase catalytic domain
60d1phka_



not modelled 100.0 24 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
61d1xbba_



not modelled 100.0 40 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
62c3lijA_



not modelled 100.0 27 PDB header:transferase
Chain: A: PDB Molecule:calcium/calmodulin dependent protein kinase with
PDBTitle: crystal structure of full length cpcdpk3 (cgd5_820) in2 complex with ca2+ and amppnp
63c2bujA_



not modelled 100.0 21 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase 16;
PDBTitle: crystal structure of the human serine-threonine kinase 162 in complex with staurosporine
64c3fbvL_



not modelled 100.0 24 PDB header:transferase, hydrolase
Chain: L: PDB Molecule:serine/threonine-protein kinase/endoribonuclease ire1;
PDBTitle: crystal structure of the oligomer formed by the kinase-ribonuclease2 domain of ire1
65c2a1aB_



not modelled 100.0 23 PDB header:protein synthesis/transferase
Chain: B: PDB Molecule:interferon-induced, double-stranded rna-activated protein
PDBTitle: pkr kinase domain-eif2alpha complex
66c3eygA_



not modelled 100.0 35 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase;
PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes
67d1mp8a_



not modelled 100.0 39 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
68c1yvjA_



not modelled 100.0 33 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase jak3;
PDBTitle: crystal structure of the jak3 kinase domain in complex with2 a staurosporine analogue
69c3vw6B_



not modelled 100.0 26 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:mitogen-activated protein kinase kinase kinase 5;
PDBTitle: crystal structure of human apoptosis signal-regulating kinase 1 (ask1)2 with imidazopyridine inhibitor
70c2wtkC_



not modelled 100.0 24 PDB header:transferase/metal-binding protein
Chain: C: PDB Molecule:serine/threonine-protein kinase 11;
PDBTitle: structure of the heterotrimeric lkb1-stradalpha-mo25alpha2 complex
71c2j51A_



not modelled 100.0 23 PDB header:transferase
Chain: A: PDB Molecule:ste20-like serine/threonine-protein kinase;
PDBTitle: crystal structure of human ste20-like kinase bound to 5-2 amino-3-((4-(aminosulfonyl)phenyl)amino)-n-(2,6-3 difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide
72c3d9vA_



not modelled 100.0 22 PDB header:transferase
Chain: A: PDB Molecule:rho-associated protein kinase 1;
PDBTitle: crystal structure of rock i bound to h-1152p a di-2 methylated variant of fasudil
73c2qg5D_



not modelled 100.0 24 PDB header:transferase
Chain: D: PDB Molecule:calcium/calmodulin-dependent protein kinase;
PDBTitle: cryptosporidium parvum calcium dependent protein kinase cgd7_1840
74d1jpaa_



not modelled 100.0 40 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
75d1uwha_



not modelled 100.0 35 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
76c2clqA_



not modelled 100.0 27 PDB header:transferase
Chain: A: PDB Molecule:mitogen-activated protein kinase kinase kinase 5;
PDBTitle: structure of mitogen-activated protein kinase kinase kinase2 5
77d2jfla1



not modelled 100.0 24 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
78c3dfaA_



not modelled 100.0 27 PDB header:transferase
Chain: A: PDB Molecule:calcium-dependent protein kinase cgd3_920;
PDBTitle: crystal structure of kinase domain of calcium-dependent protein kinase2 cgd3_920 from cryptosporidium parvum
79c2bmcD_



not modelled 100.0 25 PDB header:transferase
Chain: D: PDB Molecule:serine threonine-protein kinase 6;
PDBTitle: aurora-2 t287d t288d complexed with pha-680632
80c4eutA_



not modelled 100.0 22 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:serine/threonine-protein kinase tbk1;
PDBTitle: structure of bx-795 complexed with unphosphorylated human tbk1 kinase-2 uld domain
81c3fupB_



not modelled 100.0 37 PDB header:transferase
Chain: B: PDB Molecule:tyrosine-protein kinase jak2;
PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes
82d1mqba_



not modelled 100.0 43 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
83c3d4qA_



not modelled 100.0 36 PDB header:transferase
Chain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase;
PDBTitle: pyrazole-based inhibitors of b-raf kinase
84c3v5qB_



not modelled 100.0 37 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:nt-3 growth factor receptor;
PDBTitle: discovery of a selective trk inhibitor with efficacy in rodent cancer2 tumor models
85d1fvra_



not modelled 100.0 38 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
86c3cc6A_



not modelled 100.0 36 PDB header:transferase
Chain: A: PDB Molecule:protein tyrosine kinase 2 beta;
PDBTitle: crystal structure of kinase domain of protein tyrosine kinase 2 beta2 (ptk2b)
87c3p23B_



not modelled 100.0 24 PDB header:hydrolase, transferase
Chain: B: PDB Molecule:serine/threonine-protein kinase/endoribonuclease ire1;
PDBTitle: crystal structure of the human kinase and rnase domains in complex2 with adp
88d1rjba_



not modelled 100.0 45 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
89c2w1iB_



not modelled 100.0 37 PDB header:transferase
Chain: B: PDB Molecule:jak2;
PDBTitle: structure determination of aurora kinase in complex with2 inhibitor
90c2cgvA_



not modelled 100.0 24 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase chk1;
PDBTitle: identification of chemically diverse chk1 inhibitors by2 receptor-based virtual screening
91c2y7jB_



not modelled 100.0 22 PDB header:transferase
Chain: B: PDB Molecule:phosphorylase b kinase gamma catalytic chain,
PDBTitle: structure of human phosphorylase kinase, gamma 2
92c3comB_



not modelled 100.0 29 PDB header:transferase
Chain: B: PDB Molecule:serine/threonine-protein kinase 4;
PDBTitle: crystal structure of mst1 kinase
93c2a27B_



not modelled 100.0 24 PDB header:transferase
Chain: B: PDB Molecule:death-associated protein kinase 2;
PDBTitle: human drp-1 kinase, w305s s308a d40 mutant, crystal form with 82 monomers in the asymmetric unit
94c3hztA_



not modelled 100.0 29 PDB header:transferase
Chain: A: PDB Molecule:calcium-dependent protein kinase 3;
PDBTitle: crystal structure of toxoplasma gondii cdpk3, tgme49_105860
95d1ckia_



not modelled 100.0 23 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
96c2chlA_



not modelled 100.0 23 PDB header:transferase
Chain: A: PDB Molecule:casein kinase i isoform gamma-3;
PDBTitle: structure of casein kinase 1 gamma 3
97d1jksa_



not modelled 100.0 25 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
98c3lxnA_



not modelled 100.0 35 PDB header:transferase
Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2;
PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6
99d1nvra_



not modelled 100.0 25 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
100c2qobA_



not modelled 100.0 42 PDB header:transferase
Chain: A: PDB Molecule:ephrin receptor;
PDBTitle: human epha3 kinase domain, base structure
101c2wqmA_



not modelled 100.0 26 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase nek7;
PDBTitle: structure of apo human nek7
102c3sv0A_



not modelled 100.0 22 PDB header:transferase
Chain: A: PDB Molecule:casein kinase i-like;
PDBTitle: crystal structure of casein kinase-1 like protein in plant
103c2bdwB_



not modelled 100.0 23 PDB header:transferase
Chain: B: PDB Molecule:hypothetical protein k11e8.1d;
PDBTitle: crystal structure of the auto-inhibited kinase domain of2 calcium/calmodulin activated kinase ii
104c1mruB_



not modelled 100.0 26 PDB header:transferase
Chain: B: PDB Molecule:probable serine/threonine-protein kinase pknb;
PDBTitle: intracellular ser/thr protein kinase domain of2 mycobacterium tuberculosis pknb.
105c2ya9A_



not modelled 100.0 23 PDB header:transferase
Chain: A: PDB Molecule:death-associated protein kinase 2;
PDBTitle: crystal structure of the autoinhibited form of mouse dapk2
106d1o6ya_



not modelled 100.0 28 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
107d1koba_



not modelled 100.0 21 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
108c2wtkB_



not modelled 100.0 21 PDB header:transferase/metal-binding protein
Chain: B: PDB Molecule:ste20-related kinase adapter protein alpha;
PDBTitle: structure of the heterotrimeric lkb1-stradalpha-mo25alpha2 complex
109c1xjdA_



not modelled 100.0 25 PDB header:transferase
Chain: A: PDB Molecule:protein kinase c, theta type;
PDBTitle: crystal structure of pkc-theta complexed with staurosporine2 at 2a resolution
110d1xjda_



not modelled 100.0 25 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
111c2zv2A_



not modelled 100.0 25 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:calcium/calmodulin-dependent protein kinase kinase 2;
PDBTitle: crystal structure of human calcium/calmodulin-dependent protein kinase2 kinase 2, beta, camkk2 kinase domain in complex with sto-609
112c2vd5A_



not modelled 100.0 22 PDB header:transferase
Chain: A: PDB Molecule:dmpk protein;
PDBTitle: structure of human myotonic dystrophy protein kinase in2 complex with the bisindoylmaleide inhibitor bim viii
113c2pziA_



not modelled 100.0 21 PDB header:transferase
Chain: A: PDB Molecule:probable serine/threonine-protein kinase pkng;
PDBTitle: crystal structure of protein kinase pkng from mycobacterium2 tuberculosis in complex with tetrahydrobenzothiophene ax20017
114d1xkka_



not modelled 100.0 36 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
115c1xkkA_



not modelled 100.0 36 PDB header:transferase
Chain: A: PDB Molecule:epidermal growth factor receptor;
PDBTitle: egfr kinase domain complexed with a quinazoline inhibitor-2 gw572016
116c2x4fA_



not modelled 100.0 20 PDB header:transferase
Chain: A: PDB Molecule:myosin light chain kinase family member 4;
PDBTitle: the crystal structure of the human myosin light chain2 kinase loc340156.
117c3p86B_



not modelled 100.0 35 PDB header:transferase
Chain: B: PDB Molecule:serine/threonine-protein kinase ctr1;
PDBTitle: crystal structure of ctr1 kinase domain mutant d676n in complex with2 staurosporine
118d1koaa2



not modelled 100.0 22 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
119c4eqmE_



not modelled 100.0 22 PDB header:transferase
Chain: E: PDB Molecule:protein kinase;
PDBTitle: structural analysis of staphylococcus aureus serine/threonine kinase2 pknb
120c2c47D_



not modelled 100.0 21 PDB header:transferase
Chain: D: PDB Molecule:casein kinase 1 gamma 2 isoform;
PDBTitle: structure of casein kinase 1 gamma 2

Binding site prediction 

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If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite