Secondary structure and disorder prediction

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Sequence		M	T	M	S	L	E	V	F	E	K	L	E	A	K	V	Q	Q	A	I	D	T	I	T	L	L	Q	M	E	I	E	E	L	K	E	K	N	N	S	L	S	Q	E	V	Q	N	A	Q	H	Q	R	E	E	L	E	R	E	N	N	H	L
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.
Sequence		K	E	Q	Q	N	G	W	Q	E	R	L	Q	A	L	L	G	R	M	E	E	V
Secondary structure
SS confidence
Disorder																	?	?		?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2jee chain A Region: 3 - 80 Aligned: 78 Modelled: 78 Confidence: 100.0% Identity: 100% PDB header:cell cycle Chain: A: PDB Molecule:yiiu; PDBTitle: xray structure of e. coli yiiu Phyre2 PDB 3u59 chain C Region: 8 - 74 Aligned: 67 Modelled: 67 Confidence: 91.8% Identity: 18% PDB header:contractile protein Chain: C: PDB Molecule:tropomyosin beta chain; PDBTitle: n-terminal 98-aa fragment of smooth muscle tropomyosin beta Phyre2 PDB 3ghg chain K Region: 4 - 80 Aligned: 77 Modelled: 77 Confidence: 89.3% Identity: 12% PDB header:blood clotting Chain: K: PDB Molecule:fibrinogen beta chain; PDBTitle: crystal structure of human fibrinogen Phyre2 PDB 3oja chain B Region: 6 - 74 Aligned: 69 Modelled: 69 Confidence: 89.1% Identity: 14% PDB header:protein binding Chain: B: PDB Molecule:anopheles plasmodium-responsive leucine-rich repeat protein PDBTitle: crystal structure of lrim1/apl1c complex Phyre2 PDB 2w6a chain B Region: 7 - 62 Aligned: 42 Modelled: 42 Confidence: 86.4% Identity: 38% PDB header:signaling protein Chain: B: PDB Molecule:arf gtpase-activating protein git1; PDBTitle: x-ray structure of the dimeric git1 coiled-coil domain Phyre2 PDB 2fxm chain B Region: 8 - 80 Aligned: 73 Modelled: 73 Confidence: 81.4% Identity: 14% PDB header:contractile protein Chain: B: PDB Molecule:myosin heavy chain, cardiac muscle beta isoform; PDBTitle: structure of the human beta-myosin s2 fragment Phyre2 PDB 1cz7 chain C Region: 25 - 78 Aligned: 54 Modelled: 54 Confidence: 79.5% Identity: 13% PDB header:contractile protein Chain: C: PDB Molecule:microtubule motor protein ncd; PDBTitle: the crystal structure of a minus-end directed microtubule2 motor protein ncd reveals variable dimer conformations Phyre2 PDB 1deq chain O Region: 6 - 80 Aligned: 75 Modelled: 75 Confidence: 78.9% Identity: 11% PDB header: PDB COMPND: Phyre2 PDB 3ol1 chain A Region: 8 - 74 Aligned: 67 Modelled: 67 Confidence: 78.8% Identity: 12% PDB header:structural protein Chain: A: PDB Molecule:vimentin; PDBTitle: crystal structure of vimentin (fragment 144-251) from homo sapiens,2 northeast structural genomics consortium target hr4796b Phyre2 PDB 2yy0 chain D Region: 22 - 67 Aligned: 32 Modelled: 32 Confidence: 78.5% Identity: 41% PDB header:transcription Chain: D: PDB Molecule:c-myc-binding protein; PDBTitle: crystal structure of ms0802, c-myc-1 binding protein domain2 from homo sapiens Phyre2 PDB 1gd2 chain G Region: 20 - 60 Aligned: 41 Modelled: 41 Confidence: 78.4% Identity: 27% PDB header:transcription/dna Chain: G: PDB Molecule:transcription factor pap1; PDBTitle: crystal structure of bzip transcription factor pap1 bound2 to dna Phyre2 PDB 1yvl chain B Region: 6 - 78 Aligned: 73 Modelled: 73 Confidence: 77.5% Identity: 10% PDB header:signaling protein Chain: B: PDB Molecule:signal transducer and activator of transcription PDBTitle: structure of unphosphorylated stat1 Phyre2 PDB 1dip chain A Region: 28 - 62 Aligned: 28 Modelled: 35 Confidence: 75.7% Identity: 50% PDB header:acetylation Chain: A: PDB Molecule:delta-sleep-inducing peptide immunoreactive PDBTitle: the solution structure of porcine delta-sleep-inducing2 peptide immunoreactive peptide, nmr, 10 structures Phyre2 PDB 1ei3 chain E Region: 6 - 80 Aligned: 75 Modelled: 75 Confidence: 75.6% Identity: 7% PDB header: PDB COMPND: Phyre2 PDB 1j1d chain F Region: 29 - 78 Aligned: 50 Modelled: 50 Confidence: 71.8% Identity: 16% PDB header:contractile protein Chain: F: PDB Molecule:troponin i; PDBTitle: crystal structure of the 46kda domain of human cardiac2 troponin in the ca2+ saturated form Phyre2 PDB 2b9c chain A Region: 8 - 80 Aligned: 73 Modelled: 73 Confidence: 71.1% Identity: 10% PDB header:contractile protein Chain: A: PDB Molecule:striated-muscle alpha tropomyosin; PDBTitle: structure of tropomyosin's mid-region: bending and binding2 sites for actin Phyre2 PDB 2wt7 chain B Region: 33 - 74 Aligned: 42 Modelled: 42 Confidence: 69.7% Identity: 19% PDB header:transcription Chain: B: PDB Molecule:transcription factor mafb; PDBTitle: crystal structure of the bzip heterodimeric complex2 mafb:cfos bound to dna Phyre2 PDB 2v66 chain C Region: 9 - 80 Aligned: 72 Modelled: 72 Confidence: 69.4% Identity: 14% PDB header:structural protein Chain: C: PDB Molecule:nuclear distribution protein nude-like 1; PDBTitle: crystal structure of the coiled-coil domain of ndel1 (a.a.2 58 to 169)c Phyre2 PDB 3o0z chain D Region: 2 - 80 Aligned: 79 Modelled: 79 Confidence: 68.9% Identity: 15% PDB header:transferase Chain: D: PDB Molecule:rho-associated protein kinase 1; PDBTitle: crystal structure of a coiled-coil domain from human rock i Phyre2 PDB 1an2 chain A Region: 15 - 53 Aligned: 39 Modelled: 39 Confidence: 66.7% Identity: 13% Fold: HLH-like Superfamily: HLH, helix-loop-helix DNA-binding domain Family: HLH, helix-loop-helix DNA-binding domain Phyre2 1 c2jeeA_ 2 c3u59C_ 3 c3ghgK_ 4 c3ojaB_ 5 c2w6aB_ 6 c2fxmB_ 7 c1cz7C_ 8 c1deqO_ 9 c3ol1A_ 10 c2yy0D_ 11 c1gd2G_ 12 c1yvlB_ 13 c1dipA_ 14 c1ei3E_ 15 c1j1dF_ 16 c2b9cA_ 17 c2wt7B_ 18 c2v66C_ 19 c3o0zD_ 20 d1an2a_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2jeeA_ 100.0 100 PDB header:cell cycle Chain: A: PDB Molecule:yiiu; PDBTitle: xray structure of e. coli yiiu 2 c3u59C_ 91.8 18 PDB header:contractile protein Chain: C: PDB Molecule:tropomyosin beta chain; PDBTitle: n-terminal 98-aa fragment of smooth muscle tropomyosin beta 3 c3ghgK_ 89.3 12 PDB header:blood clotting Chain: K: PDB Molecule:fibrinogen beta chain; PDBTitle: crystal structure of human fibrinogen 4 c3ojaB_ 89.1 14 PDB header:protein binding Chain: B: PDB Molecule:anopheles plasmodium-responsive leucine-rich repeat protein PDBTitle: crystal structure of lrim1/apl1c complex 5 c2w6aB_ 86.4 38 PDB header:signaling protein Chain: B: PDB Molecule:arf gtpase-activating protein git1; PDBTitle: x-ray structure of the dimeric git1 coiled-coil domain 6 c2fxmB_ 81.4 14 PDB header:contractile protein Chain: B: PDB Molecule:myosin heavy chain, cardiac muscle beta isoform; PDBTitle: structure of the human beta-myosin s2 fragment 7 c1cz7C_ 79.5 13 PDB header:contractile protein Chain: C: PDB Molecule:microtubule motor protein ncd; PDBTitle: the crystal structure of a minus-end directed microtubule2 motor protein ncd reveals variable dimer conformations 8 c1deqO_ 78.9 11 PDB header: PDB COMPND: 9 c3ol1A_ 78.8 12 PDB header:structural protein Chain: A: PDB Molecule:vimentin; PDBTitle: crystal structure of vimentin (fragment 144-251) from homo sapiens,2 northeast structural genomics consortium target hr4796b 10 c2yy0D_ 78.5 41 PDB header:transcription Chain: D: PDB Molecule:c-myc-binding protein; PDBTitle: crystal structure of ms0802, c-myc-1 binding protein domain2 from homo sapiens 11 c1gd2G_ 78.4 27 PDB header:transcription/dna Chain: G: PDB Molecule:transcription factor pap1; PDBTitle: crystal structure of bzip transcription factor pap1 bound2 to dna 12 c1yvlB_ 77.5 10 PDB header:signaling protein Chain: B: PDB Molecule:signal transducer and activator of transcription PDBTitle: structure of unphosphorylated stat1 13 c1dipA_ 75.7 50 PDB header:acetylation Chain: A: PDB Molecule:delta-sleep-inducing peptide immunoreactive PDBTitle: the solution structure of porcine delta-sleep-inducing2 peptide immunoreactive peptide, nmr, 10 structures 14 c1ei3E_ 75.6 7 PDB header: PDB COMPND: 15 c1j1dF_ 71.8 16 PDB header:contractile protein Chain: F: PDB Molecule:troponin i; PDBTitle: crystal structure of the 46kda domain of human cardiac2 troponin in the ca2+ saturated form 16 c2b9cA_ 71.1 10 PDB header:contractile protein Chain: A: PDB Molecule:striated-muscle alpha tropomyosin; PDBTitle: structure of tropomyosin's mid-region: bending and binding2 sites for actin 17 c2wt7B_ 69.7 19 PDB header:transcription Chain: B: PDB Molecule:transcription factor mafb; PDBTitle: crystal structure of the bzip heterodimeric complex2 mafb:cfos bound to dna 18 c2v66C_ 69.4 14 PDB header:structural protein Chain: C: PDB Molecule:nuclear distribution protein nude-like 1; PDBTitle: crystal structure of the coiled-coil domain of ndel1 (a.a.2 58 to 169)c 19 c3o0zD_ 68.9 15 PDB header:transferase Chain: D: PDB Molecule:rho-associated protein kinase 1; PDBTitle: crystal structure of a coiled-coil domain from human rock i 20 d1an2a_ 66.7 13 Fold:HLH-like Superfamily:HLH, helix-loop-helix DNA-binding domain Family:HLH, helix-loop-helix DNA-binding domain 21 c2d3eD_ not modelled 66.4 16 PDB header:contractile protein Chain: D: PDB Molecule:general control protein gcn4 and tropomyosin 1 PDBTitle: crystal structure of the c-terminal fragment of rabbit2 skeletal alpha-tropomyosin 22 c2oqqB_ not modelled 65.1 29 PDB header:transcription Chain: B: PDB Molecule:transcription factor hy5; PDBTitle: crystal structure of hy5 leucine zipper homodimer from2 arabidopsis thaliana 23 c3mudA_ not modelled 65.1 24 PDB header:contractile protein Chain: A: PDB Molecule:dna repair protein xrcc4, tropomyosin alpha-1 chain; PDBTitle: structure of the tropomyosin overlap complex from chicken smooth2 muscle 24 c1c1gA_ not modelled 65.0 20 PDB header:contractile protein Chain: A: PDB Molecule:tropomyosin; PDBTitle: crystal structure of tropomyosin at 7 angstroms resolution2 in the spermine-induced crystal form 25 c1bg1A_ not modelled 64.8 16 PDB header:transcription/dna Chain: A: PDB Molecule:protein (transcription factor stat3b); PDBTitle: transcription factor stat3b/dna complex 26 c2w6bA_ not modelled 64.5 29 PDB header:signaling protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 7; PDBTitle: crystal structure of the trimeric beta-pix coiled-coil2 domain 27 d1x4ta1 not modelled 63.9 32 Fold:Long alpha-hairpin Superfamily:ISY1 domain-like Family:ISY1 N-terminal domain-like 28 c1fosE_ not modelled 63.5 25 PDB header:transcription/dna Chain: E: PDB Molecule:p55-c-fos proto-oncogene protein; PDBTitle: two human c-fos:c-jun:dna complexes 29 d2p90a1 not modelled 63.3 18 Fold:Phosphorylase/hydrolase-like Superfamily:Cgl1923-like Family:Cgl1923-like 30 c3hizB_ not modelled 62.9 9 PDB header:transferase/oncoprotein Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha 31 c1ci6A_ not modelled 62.8 33 PDB header:transcription Chain: A: PDB Molecule:transcription factor atf-4; PDBTitle: transcription factor atf4-c/ebp beta bzip heterodimer 32 c3a7pB_ not modelled 62.1 14 PDB header:protein transport Chain: B: PDB Molecule:autophagy protein 16; PDBTitle: the crystal structure of saccharomyces cerevisiae atg16 33 c2efrB_ not modelled 60.1 11 PDB header:contractile protein Chain: B: PDB Molecule:general control protein gcn4 and tropomyosin 1 alpha chain; PDBTitle: crystal structure of the c-terminal tropomyosin fragment with n- and2 c-terminal extensions of the leucine zipper at 1.8 angstroms3 resolution 34 c1fosF_ not modelled 59.3 26 PDB header:transcription/dna Chain: F: PDB Molecule:c-jun proto-oncogene protein; PDBTitle: two human c-fos:c-jun:dna complexes 35 c2gd7B_ not modelled 59.3 14 PDB header:transcription Chain: B: PDB Molecule:hexim1 protein; PDBTitle: the structure of the cyclin t-binding domain of hexim12 reveals the molecular basis for regulation of3 transcription elongation 36 d1uklc_ not modelled 57.3 33 Fold:HLH-like Superfamily:HLH, helix-loop-helix DNA-binding domain Family:HLH, helix-loop-helix DNA-binding domain 37 c2e43A_ not modelled 56.2 31 PDB header:transcription/dna Chain: A: PDB Molecule:ccaat/enhancer-binding protein beta; PDBTitle: crystal structure of c/ebpbeta bzip homodimer k269a mutant2 bound to a high affinity dna fragment 38 c1bf5A_ not modelled 56.0 18 PDB header:gene regulation/dna Chain: A: PDB Molecule:signal transducer and activator of transcription PDBTitle: tyrosine phosphorylated stat-1/dna complex 39 c3hnwB_ not modelled 54.7 23 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a basic coiled-coil protein of unknown function2 from eubacterium eligens atcc 27750 40 c3qo8A_ not modelled 53.3 15 PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase, cytoplasmic; PDBTitle: crystal structure of seryl-trna synthetase from candida albicans 41 c2v71A_ not modelled 52.6 19 PDB header:nuclear protein Chain: A: PDB Molecule:nuclear distribution protein nude-like 1; PDBTitle: coiled-coil region of nudel 42 d1am9a_ not modelled 51.9 35 Fold:HLH-like Superfamily:HLH, helix-loop-helix DNA-binding domain Family:HLH, helix-loop-helix DNA-binding domain 43 d1r05a_ not modelled 50.7 15 Fold:HLH-like Superfamily:HLH, helix-loop-helix DNA-binding domain Family:HLH, helix-loop-helix DNA-binding domain 44 c2j5uB_ not modelled 49.8 41 PDB header:cell shape regulation Chain: B: PDB Molecule:mrec protein; PDBTitle: mrec lysteria monocytogenes 45 c2w83C_ not modelled 49.6 22 PDB header:protein transport Chain: C: PDB Molecule:c-jun-amino-terminal kinase-interacting protein PDBTitle: crystal structure of the arf6 gtpase in complex with a2 specific effector, jip4 46 d1nkpb_ not modelled 49.6 13 Fold:HLH-like Superfamily:HLH, helix-loop-helix DNA-binding domain Family:HLH, helix-loop-helix DNA-binding domain 47 c3q4fG_ not modelled 47.6 30 PDB header:dna binding protein/protein binding Chain: G: PDB Molecule:dna repair protein xrcc4; PDBTitle: crystal structure of xrcc4/xlf-cernunnos complex 48 c1ei3C_ not modelled 45.9 16 PDB header: PDB COMPND: 49 c1rb1B_ not modelled 45.4 38 PDB header:dna binding protein Chain: B: PDB Molecule:general control protein gcn4; PDBTitle: gcn4-leucine zipper core mutant as n16a trigonal automatic2 solution 50 c1rb1A_ not modelled 45.4 38 PDB header:dna binding protein Chain: A: PDB Molecule:general control protein gcn4; PDBTitle: gcn4-leucine zipper core mutant as n16a trigonal automatic2 solution 51 c3k7zA_ not modelled 45.4 38 PDB header:dna binding protein Chain: A: PDB Molecule:general control protein gcn4; PDBTitle: gcn4-leucine zipper core mutant as n16a trigonal automatic2 solution 52 c3k7zB_ not modelled 45.4 38 PDB header:dna binding protein Chain: B: PDB Molecule:general control protein gcn4; PDBTitle: gcn4-leucine zipper core mutant as n16a trigonal automatic2 solution 53 d1nkpa_ not modelled 45.1 23 Fold:HLH-like Superfamily:HLH, helix-loop-helix DNA-binding domain Family:HLH, helix-loop-helix DNA-binding domain 54 d1nlwa_ not modelled 45.1 18 Fold:HLH-like Superfamily:HLH, helix-loop-helix DNA-binding domain Family:HLH, helix-loop-helix DNA-binding domain 55 c2gl2B_ not modelled 45.1 14 PDB header:cell adhesion Chain: B: PDB Molecule:adhesion a; PDBTitle: crystal structure of the tetra muntant (t66g,r67g,f68g,2 y69g) of bacterial adhesin fada 56 c1ij2C_ not modelled 45.0 38 PDB header:transcription Chain: C: PDB Molecule:general control protein gcn4; PDBTitle: gcn4-pvtl coiled-coil trimer with threonine at the a(16)2 position 57 c1ij3C_ not modelled 44.9 38 PDB header:transcription Chain: C: PDB Molecule:general control protein gcn4; PDBTitle: gcn4-pvsl coiled-coil trimer with serine at the a(16)2 position 58 c3dtpA_ not modelled 43.5 16 PDB header:contractile protein Chain: A: PDB Molecule:myosin 2 heavy chain chimera of smooth and PDBTitle: tarantula heavy meromyosin obtained by flexible docking to2 tarantula muscle thick filament cryo-em 3d-map 59 c3a5tB_ not modelled 43.5 22 PDB header:transcription regulator/dna Chain: B: PDB Molecule:transcription factor mafg; PDBTitle: crystal structure of mafg-dna complex 60 c1ytzI_ not modelled 43.4 18 PDB header:contractile protein Chain: I: PDB Molecule:troponin i; PDBTitle: crystal structure of skeletal muscle troponin in the ca2+-2 activated state 61 c1ij2B_ not modelled 43.4 38 PDB header:transcription Chain: B: PDB Molecule:general control protein gcn4; PDBTitle: gcn4-pvtl coiled-coil trimer with threonine at the a(16)2 position 62 c1ci6B_ not modelled 41.3 32 PDB header:transcription Chain: B: PDB Molecule:transcription factor c/ebp beta; PDBTitle: transcription factor atf4-c/ebp beta bzip heterodimer 63 c1ciiA_ not modelled 37.9 16 PDB header:transmembrane protein Chain: A: PDB Molecule:colicin ia; PDBTitle: colicin ia 64 c1junB_ not modelled 37.9 23 PDB header:transcription regulation Chain: B: PDB Molecule:c-jun homodimer; PDBTitle: nmr study of c-jun homodimer 65 c1deqF_ not modelled 37.6 10 PDB header: PDB COMPND: 66 c3na7A_ not modelled 36.8 8 PDB header:gene regulation, chaperone Chain: A: PDB Molecule:hp0958; PDBTitle: 2.2 angstrom structure of the hp0958 protein from helicobacter pylori2 ccug 17874 67 c1t2kD_ not modelled 35.0 24 PDB header:transcription/dna Chain: D: PDB Molecule:cyclic-amp-dependent transcription factor atf-2; PDBTitle: structure of the dna binding domains of irf3, atf-2 and jun2 bound to dna 68 c1ik9B_ not modelled 32.6 24 PDB header:gene regulation/ligase Chain: B: PDB Molecule:dna repair protein xrcc4; PDBTitle: crystal structure of a xrcc4-dna ligase iv complex 69 c3l9oA_ not modelled 32.1 13 PDB header:hydrolase Chain: A: PDB Molecule:atp-dependent rna helicase dob1; PDBTitle: crystal structure of mtr4, a co-factor of the nuclear exosome 70 c3cwgA_ not modelled 29.9 19 PDB header:transcription Chain: A: PDB Molecule:signal transducer and activator of transcription PDBTitle: unphosphorylated mouse stat3 core fragment 71 c2zxxA_ not modelled 29.9 22 PDB header:cell cycle/replication Chain: A: PDB Molecule:geminin; PDBTitle: crystal structure of cdt1/geminin complex 72 c2ve7A_ not modelled 27.7 18 PDB header:cell cycle Chain: A: PDB Molecule:kinetochore protein hec1, kinetochore protein spc25; PDBTitle: crystal structure of a bonsai version of the human ndc802 complex 73 c1dh3A_ not modelled 27.2 17 PDB header:transcription/dna Chain: A: PDB Molecule:transcription factor creb; PDBTitle: crystal structure of a creb bzip-cre complex reveals the2 basis for creb faimly selective dimerization and dna3 binding 74 d1hloa_ not modelled 25.7 11 Fold:HLH-like Superfamily:HLH, helix-loop-helix DNA-binding domain Family:HLH, helix-loop-helix DNA-binding domain 75 c2v4hA_ not modelled 25.6 23 PDB header:transcription Chain: A: PDB Molecule:nf-kappa-b essential modulator; PDBTitle: nemo cc2-lz domain - 1d5 darpin complex 76 c3m9bK_ not modelled 24.0 17 PDB header:chaperone Chain: K: PDB Molecule:proteasome-associated atpase; PDBTitle: crystal structure of the amino terminal coiled coil domain and the2 inter domain of the mycobacterium tuberculosis proteasomal atpase mpa 77 c2v1yB_ not modelled 23.2 16 PDB header:transferase Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit alpha; PDBTitle: structure of a phosphoinositide 3-kinase alpha adaptor-2 binding domain (abd) in a complex with the ish2 domain3 from p85 alpha 78 d1nlwe_ not modelled 22.8 26 Fold:HLH-like Superfamily:HLH, helix-loop-helix DNA-binding domain Family:HLH, helix-loop-helix DNA-binding domain 79 d2ncda_ not modelled 22.4 22 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Motor proteins 80 c4a55B_ not modelled 19.8 17 PDB header:transferase Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit alpha; PDBTitle: crystal structure of p110alpha in complex with ish2 of p85alpha and2 the inhibitor pik-108 81 c2xgjA_ not modelled 19.7 13 PDB header:hydrolase/rna Chain: A: PDB Molecule:atp-dependent rna helicase dob1; PDBTitle: structure of mtr4, a dexh helicase involved in nuclear rna2 processing and surveillance 82 c1fmhA_ not modelled 19.4 30 PDB header:transcription Chain: A: PDB Molecule:general control protein gcn4; PDBTitle: nmr solution structure of a designed heterodimeric leucine2 zipper 83 c1debA_ not modelled 19.2 26 PDB header:structural protein Chain: A: PDB Molecule:adenomatous polyposis coli protein; PDBTitle: crystal structure of the n-terminal coiled coil domain from2 apc 84 c1yv0I_ not modelled 19.0 18 PDB header:contractile protein Chain: I: PDB Molecule:troponin i, fast skeletal muscle; PDBTitle: crystal structure of skeletal muscle troponin in the ca2+-2 free state 85 c2y3aB_ not modelled 19.0 12 PDB header:transferase Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta; PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941 86 c1h3oA_ not modelled 18.9 38 PDB header:transcription/tbp-associated factors Chain: A: PDB Molecule:transcription initiation factor tfiid 135 kda PDBTitle: crystal structure of the human taf4-taf122 (tafii135-tafii20) complex 87 d1h3oa_ not modelled 18.9 38 Fold:Histone-fold Superfamily:Histone-fold Family:TBP-associated factors, TAFs 88 c2zvnF_ not modelled 17.3 23 PDB header:signaling protein/transcription Chain: F: PDB Molecule:nf-kappa-b essential modulator; PDBTitle: nemo cozi domain incomplex with diubiquitin in p2121212 space group 89 c2xdjF_ not modelled 17.2 19 PDB header:unknown function Chain: F: PDB Molecule:uncharacterized protein ybgf; PDBTitle: crystal structure of the n-terminal domain of e.coli ybgf 90 d1uk5a_ not modelled 16.5 12 Fold:Spectrin repeat-like Superfamily:BAG domain Family:BAG domain 91 d1u2ma_ not modelled 15.9 28 Fold:OmpH-like Superfamily:OmpH-like Family:OmpH-like 92 c2x7aB_ not modelled 15.1 36 PDB header:immune system Chain: B: PDB Molecule:bone marrow stromal antigen 2; PDBTitle: structural basis of hiv-1 tethering to membranes by the2 bst2-tetherin ectodomain 93 c2wukD_ not modelled 15.0 20 PDB header:cell cycle Chain: D: PDB Molecule:septum site-determining protein diviva; PDBTitle: diviva n-terminal domain, f17a mutant 94 c3lssA_ not modelled 14.4 19 PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase; PDBTitle: trypanosoma brucei seryl-trna synthetase in complex with atp 95 c1ztaA_ not modelled 14.2 33 PDB header:dna-binding motif Chain: A: PDB Molecule:leucine zipper monomer; PDBTitle: the solution structure of a leucine-zipper motif peptide 96 c2wvrB_ not modelled 14.1 24 PDB header:replication Chain: B: PDB Molecule:geminin; PDBTitle: human cdt1:geminin complex 97 c1jocA_ not modelled 14.0 25 PDB header:membrane protein Chain: A: PDB Molecule:early endosomal autoantigen 1; PDBTitle: eea1 homodimer of c-terminal fyve domain bound to inositol2 1,3-diphosphate 98 c3mtuD_ not modelled 13.8 8 PDB header:contractile protein Chain: D: PDB Molecule:tropomyosin alpha-1 chain, microtubule-associated protein PDBTitle: structure of the tropomyosin overlap complex from chicken smooth2 muscle 99 d1seta1 not modelled 13.4 18 Fold:Long alpha-hairpin Superfamily:tRNA-binding arm Family:Seryl-tRNA synthetase (SerRS)

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0