Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP39304
DateThu Jan 5 11:59:08 GMT 2012
Unique Job IDeb1eb7553952708b

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1q6oa_
Top template information
Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
Confidence and coverage
Confidence:100.0% Coverage: 99%
213 residues ( 99% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MSLPMLQVALDNQTMDSAYETTRLIAEEVDIIEVGTILCVGEGVRAVRDLKALYPHKIVL
Secondary structure 
SS confidence 
Disorder  ????
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  ADAKIADAGKILSRMCFEANADWVTVICCADINTAKGALDVAKEFNGDVQIELTGYWTWE
Secondary structure 
SS confidence 
Disorder 
???
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  QAQQWRDAGIGQVVYHRSRDAQAAGVAWGEADITAIKRLSDMGFKVTVTGGLALEDLPLF
Secondary structure 
SS confidence 
Disorder 
?
?
???
Disorder confidence 
 
   .........190.........200.........210......
Sequence  KGIPIHVFIAGRSIRDAASPVEAARQFKRSIAELWG
Secondary structure 
SS confidence 
Disorder 
?
?
??
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1q6o chain A

3D model

Region: 3 - 215
Aligned: 213
Modelled: 213
Confidence: 100.0%
Identity: 100%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Decarboxylase

Phyre2

PDB 3jr2 chain D

3D model

Region: 3 - 215
Aligned: 212
Modelled: 213
Confidence: 100.0%
Identity: 43%
PDB header:biosynthetic protein
Chain: D: PDB Molecule:hexulose-6-phosphate synthase sgbh;
PDBTitle: x-ray crystal structure of the mg-bound 3-keto-l-gulonate-6-phosphate2 decarboxylase from vibrio cholerae o1 biovar el tor str. n16961

Phyre2

PDB 3exs chain B

3D model

Region: 2 - 216
Aligned: 208
Modelled: 215
Confidence: 100.0%
Identity: 47%
PDB header:lyase
Chain: B: PDB Molecule:rmpd (hexulose-6-phosphate synthase);
PDBTitle: crystal structure of kgpdc from streptococcus mutans in2 complex with d-r5p

Phyre2

PDB 3ajx chain A

3D model

Region: 1 - 211
Aligned: 204
Modelled: 204
Confidence: 100.0%
Identity: 35%
PDB header:lyase
Chain: A: PDB Molecule:3-hexulose-6-phosphate synthase;
PDBTitle: crystal structure of 3-hexulose-6-phosphate synthase

Phyre2

PDB 3f4w chain A

3D model

Region: 1 - 215
Aligned: 210
Modelled: 212
Confidence: 100.0%
Identity: 34%
PDB header:synthase, lyase
Chain: A: PDB Molecule:putative hexulose 6 phosphate synthase;
PDBTitle: the 1.65a crystal structure of 3-hexulose-6-phosphate2 synthase from salmonella typhimurium

Phyre2

PDB 3ru6 chain C

3D model

Region: 5 - 212
Aligned: 206
Modelled: 208
Confidence: 100.0%
Identity: 17%
PDB header:lyase
Chain: C: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: 1.8 angstrom resolution crystal structure of orotidine 5'-phosphate2 decarboxylase (pyrf) from campylobacter jejuni subsp. jejuni nctc3 11168

Phyre2

PDB 1km4 chain A

3D model

Region: 1 - 211
Aligned: 205
Modelled: 211
Confidence: 100.0%
Identity: 22%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Decarboxylase

Phyre2

PDB 3tr2 chain A

3D model

Region: 4 - 211
Aligned: 206
Modelled: 208
Confidence: 100.0%
Identity: 17%
PDB header:lyase
Chain: A: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: structure of a orotidine 5'-phosphate decarboxylase (pyrf) from2 coxiella burnetii

Phyre2

PDB 1eix chain A

3D model

Region: 1 - 212
Aligned: 210
Modelled: 212
Confidence: 100.0%
Identity: 15%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Decarboxylase

Phyre2

PDB 1dbt chain A

3D model

Region: 1 - 214
Aligned: 212
Modelled: 214
Confidence: 100.0%
Identity: 17%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Decarboxylase

Phyre2

PDB 1dvj chain A

3D model

Region: 1 - 213
Aligned: 207
Modelled: 211
Confidence: 100.0%
Identity: 23%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Decarboxylase

Phyre2

PDB 3tfx chain B

3D model

Region: 4 - 212
Aligned: 206
Modelled: 208
Confidence: 100.0%
Identity: 16%
PDB header:lyase
Chain: B: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: crystal structure of orotidine 5'-phosphate decarboxylase from2 lactobacillus acidophilus

Phyre2

PDB 3ldv chain B

3D model

Region: 2 - 211
Aligned: 208
Modelled: 210
Confidence: 100.0%
Identity: 17%
PDB header:lyase
Chain: B: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: 1.77 angstrom resolution crystal structure of orotidine 5'-2 phosphate decarboxylase from vibrio cholerae o1 biovar3 eltor str. n16961

Phyre2

PDB 2yyt chain A

3D model

Region: 6 - 212
Aligned: 199
Modelled: 201
Confidence: 100.0%
Identity: 18%
PDB header:lyase
Chain: A: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: crystal structure of uncharacterized conserved protein from2 geobacillus kaustophilus

Phyre2

PDB 2czd chain A domain 1

3D model

Region: 5 - 212
Aligned: 201
Modelled: 208
Confidence: 100.0%
Identity: 23%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Decarboxylase

Phyre2

PDB 2qcn chain A

3D model

Region: 2 - 214
Aligned: 200
Modelled: 213
Confidence: 100.0%
Identity: 17%
PDB header:lyase
Chain: A: PDB Molecule:uridine 5'-monophosphate synthase;
PDBTitle: covalent complex of the orotidine-5'-monophosphate decarboxylase2 domain of human ump synthase with 6-iodo-ump

Phyre2

PDB 3bvj chain A

3D model

Region: 2 - 214
Aligned: 200
Modelled: 213
Confidence: 100.0%
Identity: 16%
PDB header:lyase
Chain: A: PDB Molecule:uridine 5'-monophosphate synthase;
PDBTitle: crystal structure of human orotidine 5'-monophosphate decarboxylase2 complexed with xmp

Phyre2

PDB 1dqw chain A

3D model

Region: 2 - 213
Aligned: 205
Modelled: 212
Confidence: 100.0%
Identity: 15%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Decarboxylase

Phyre2

PDB 3qw3 chain B

3D model

Region: 1 - 216
Aligned: 213
Modelled: 216
Confidence: 100.0%
Identity: 15%
PDB header:transferase, lyase
Chain: B: PDB Molecule:orotidine-5-phosphate decarboxylase/orotate
PDBTitle: structure of leishmania donovani omp decarboxylase

Phyre2

PDB 1vqt chain A domain 1

3D model

Region: 1 - 209
Aligned: 186
Modelled: 200
Confidence: 100.0%
Identity: 16%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Decarboxylase

Phyre2
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d1q6oa_
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c3jr2D_
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c3exsB_
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c3ajxA_
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c3f4wA_
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c3ru6C_
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d1km4a_
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c3tr2A_
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d1eixa_
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d1dbta_
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d1dvja_
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c3tfxB_
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c3ldvB_
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c2yytA_
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d2czda1
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c2qcnA_
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c3bvjA_
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d1dqwa_
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c3qw3B_
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d1vqta1
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1q6oa_
100.0 100 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
2c3jr2D_
100.0 43 PDB header:biosynthetic protein
Chain: D: PDB Molecule:hexulose-6-phosphate synthase sgbh;
PDBTitle: x-ray crystal structure of the mg-bound 3-keto-l-gulonate-6-phosphate2 decarboxylase from vibrio cholerae o1 biovar el tor str. n16961
3c3exsB_
100.0 47 PDB header:lyase
Chain: B: PDB Molecule:rmpd (hexulose-6-phosphate synthase);
PDBTitle: crystal structure of kgpdc from streptococcus mutans in2 complex with d-r5p
4c3ajxA_
100.0 35 PDB header:lyase
Chain: A: PDB Molecule:3-hexulose-6-phosphate synthase;
PDBTitle: crystal structure of 3-hexulose-6-phosphate synthase
5c3f4wA_
100.0 34 PDB header:synthase, lyase
Chain: A: PDB Molecule:putative hexulose 6 phosphate synthase;
PDBTitle: the 1.65a crystal structure of 3-hexulose-6-phosphate2 synthase from salmonella typhimurium
6c3ru6C_
100.0 17 PDB header:lyase
Chain: C: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: 1.8 angstrom resolution crystal structure of orotidine 5'-phosphate2 decarboxylase (pyrf) from campylobacter jejuni subsp. jejuni nctc3 11168
7d1km4a_
100.0 22 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
8c3tr2A_
100.0 17 PDB header:lyase
Chain: A: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: structure of a orotidine 5'-phosphate decarboxylase (pyrf) from2 coxiella burnetii
9d1eixa_
100.0 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
10d1dbta_
100.0 17 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
11d1dvja_
100.0 23 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
12c3tfxB_
100.0 16 PDB header:lyase
Chain: B: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: crystal structure of orotidine 5'-phosphate decarboxylase from2 lactobacillus acidophilus
13c3ldvB_
100.0 17 PDB header:lyase
Chain: B: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: 1.77 angstrom resolution crystal structure of orotidine 5'-2 phosphate decarboxylase from vibrio cholerae o1 biovar3 eltor str. n16961
14c2yytA_
100.0 18 PDB header:lyase
Chain: A: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: crystal structure of uncharacterized conserved protein from2 geobacillus kaustophilus
15d2czda1
100.0 23 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
16c2qcnA_
100.0 17 PDB header:lyase
Chain: A: PDB Molecule:uridine 5'-monophosphate synthase;
PDBTitle: covalent complex of the orotidine-5'-monophosphate decarboxylase2 domain of human ump synthase with 6-iodo-ump
17c3bvjA_
100.0 16 PDB header:lyase
Chain: A: PDB Molecule:uridine 5'-monophosphate synthase;
PDBTitle: crystal structure of human orotidine 5'-monophosphate decarboxylase2 complexed with xmp
18d1dqwa_
100.0 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
19c3qw3B_
100.0 15 PDB header:transferase, lyase
Chain: B: PDB Molecule:orotidine-5-phosphate decarboxylase/orotate
PDBTitle: structure of leishmania donovani omp decarboxylase
20d1vqta1
100.0 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
21d1losc_
not modelled 100.0 21 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
22c3ct7E_
not modelled 100.0 16 PDB header:isomerase
Chain: E: PDB Molecule:d-allulose-6-phosphate 3-epimerase;
PDBTitle: crystal structure of d-allulose 6-phosphate 3-epimerase2 from escherichia coli k-12
23d1tqxa_
not modelled 100.0 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
24c3qc3B_
not modelled 100.0 13 PDB header:isomerase
Chain: B: PDB Molecule:d-ribulose-5-phosphate-3-epimerase;
PDBTitle: crystal structure of a d-ribulose-5-phosphate-3-epimerase (np_954699)2 from homo sapiens at 2.20 a resolution
25d1h1ya_
not modelled 100.0 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
26d1qopa_
not modelled 100.0 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
27c3qw4B_
not modelled 100.0 16 PDB header:transferase, lyase
Chain: B: PDB Molecule:ump synthase;
PDBTitle: structure of leishmania donovani ump synthase
28d1ujpa_
not modelled 100.0 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
29c3thaB_
not modelled 100.0 11 PDB header:lyase
Chain: B: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: tryptophan synthase subunit alpha from campylobacter jejuni.
30c3inpA_
not modelled 99.9 12 PDB header:isomerase
Chain: A: PDB Molecule:d-ribulose-phosphate 3-epimerase;
PDBTitle: 2.05 angstrom resolution crystal structure of d-ribulose-phosphate 3-2 epimerase from francisella tularensis.
31c3navB_
not modelled 99.9 14 PDB header:lyase
Chain: B: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: crystal structure of an alpha subunit of tryptophan synthase from2 vibrio cholerae o1 biovar el tor str. n16961
32d1rpxa_
not modelled 99.9 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
33c2ekcA_
not modelled 99.9 13 PDB header:lyase
Chain: A: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5
34d2ffca1
not modelled 99.9 21 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
35d1rd5a_
not modelled 99.9 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
36d2flia1
not modelled 99.9 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
37c3l52A_
not modelled 99.9 18 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: crystal structure of putative orotidine 5'-phosphate2 decarboxylase from streptomyces avermitilis ma-4680
38d2q8za1
not modelled 99.9 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
39d1geqa_
not modelled 99.9 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
40c3r89A_
not modelled 99.9 15 PDB header:lyase
Chain: A: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: crystal structure of orotidine 5-phosphate decarboxylase from2 anaerococcus prevotii dsm 20548
41d1tqja_
not modelled 99.9 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
42d2fdsa1
not modelled 99.9 19 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
43c2fdsA_
not modelled 99.9 19 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:orotidine-monophosphate-decarboxylase;
PDBTitle: crystal structure of plasmodium berghei orotidine 5'-2 monophosphate decarboxylase (ortholog of plasmodium3 falciparum pf10_0225)
44c3cu2A_
not modelled 99.9 12 PDB header:isomerase
Chain: A: PDB Molecule:ribulose-5-phosphate 3-epimerase;
PDBTitle: crystal structure of ribulose-5-phosphate 3-epimerase (yp_718263.1)2 from haemophilus somnus 129pt at 1.91 a resolution
45d1xcfa_
not modelled 99.9 12 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
46d1j5ta_
not modelled 99.8 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
47d1wbha1
not modelled 99.8 16 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
48c3gndC_
not modelled 99.8 11 PDB header:lyase
Chain: C: PDB Molecule:aldolase lsrf;
PDBTitle: crystal structure of e. coli lsrf in complex with ribulose-5-phosphate
49c2v82A_
not modelled 99.8 16 PDB header:lyase
Chain: A: PDB Molecule:2-dehydro-3-deoxy-6-phosphogalactonate aldolase;
PDBTitle: kdpgal complexed to kdpgal
50d1ojxa_
not modelled 99.8 13 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
51d1piia2
not modelled 99.8 12 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
52d1wa3a1
not modelled 99.8 15 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
53c3igsB_
not modelled 99.7 13 PDB header:isomerase
Chain: B: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase 2;
PDBTitle: structure of the salmonella enterica n-acetylmannosamine-6-phosphate2 2-epimerase
54d1xi3a_
not modelled 99.7 13 Fold:TIM beta/alpha-barrel
Superfamily:Thiamin phosphate synthase
Family:Thiamin phosphate synthase
55c3q58A_
not modelled 99.7 13 PDB header:isomerase
Chain: A: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase;
PDBTitle: structure of n-acetylmannosamine-6-phosphate epimerase from salmonella2 enterica
56c3qjaA_
not modelled 99.7 14 PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of the mycobacterium tuberculosis indole-3-glycerol2 phosphate synthase (trpc) in apo form
57d1vhca_
not modelled 99.7 17 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
58d1i4na_
not modelled 99.7 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
59d2tpsa_
not modelled 99.7 12 Fold:TIM beta/alpha-barrel
Superfamily:Thiamin phosphate synthase
Family:Thiamin phosphate synthase
60c2qjhH_
not modelled 99.7 11 PDB header:lyase
Chain: H: PDB Molecule:putative aldolase mj0400;
PDBTitle: m. jannaschii adh synthase covalently bound to2 dihydroxyacetone phosphate
61c1yadD_
not modelled 99.7 14 PDB header:transcription
Chain: D: PDB Molecule:regulatory protein teni;
PDBTitle: structure of teni from bacillus subtilis
62d1vc4a_
not modelled 99.7 12 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
63d1a53a_
not modelled 99.7 10 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
64c2c3zA_
not modelled 99.7 11 PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus
65d1yxya1
not modelled 99.7 19 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:NanE-like
66c3labA_
not modelled 99.7 21 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative kdpg (2-keto-3-deoxy-6-phosphogluconate)
PDBTitle: crystal structure of a putative kdpg (2-keto-3-deoxy-6-2 phosphogluconate) aldolase from oleispira antarctica
67d1y0ea_
not modelled 99.6 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:NanE-like
68d1mxsa_
not modelled 99.6 15 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
69c3o63B_
not modelled 99.6 15 PDB header:transferase
Chain: B: PDB Molecule:probable thiamine-phosphate pyrophosphorylase;
PDBTitle: crystal structure of thiamin phosphate synthase from mycobacterium2 tuberculosis
70d1w0ma_
not modelled 99.6 14 Fold:TIM beta/alpha-barrel
Superfamily:Triosephosphate isomerase (TIM)
Family:Triosephosphate isomerase (TIM)
71d1hg3a_
not modelled 99.6 13 Fold:TIM beta/alpha-barrel
Superfamily:Triosephosphate isomerase (TIM)
Family:Triosephosphate isomerase (TIM)
72c1piiA_
not modelled 99.5 13 PDB header:bifunctional(isomerase and synthase)
Chain: A: PDB Molecule:n-(5'phosphoribosyl)anthranilate isomerase;
PDBTitle: three-dimensional structure of the bifunctional enzyme2 phosphoribosylanthranilate isomerase:3 indoleglycerolphosphate synthase from escherichia coli4 refined at 2.0 angstroms resolution
73c3nm3D_
not modelled 99.5 9 PDB header:transferase
Chain: D: PDB Molecule:thiamine biosynthetic bifunctional enzyme;
PDBTitle: the crystal structure of candida glabrata thi6, a bifunctional enzyme2 involved in thiamin biosyhthesis of eukaryotes
74d1viza_
not modelled 99.5 11 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
75c2yw3E_
not modelled 99.5 17 PDB header:lyase
Chain: E: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase/2-deydro-3-
PDBTitle: crystal structure analysis of the 4-hydroxy-2-oxoglutarate aldolase/2-2 deydro-3-deoxyphosphogluconate aldolase from tthb1
76d1wv2a_
not modelled 99.4 16 Fold:TIM beta/alpha-barrel
Superfamily:ThiG-like
Family:ThiG-like
77d2f6ua1
not modelled 99.4 12 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
78c2htmB_
not modelled 99.4 17 PDB header:biosynthetic protein
Chain: B: PDB Molecule:thiazole biosynthesis protein thig;
PDBTitle: crystal structure of ttha0676 from thermus thermophilus hb8
79d1h5ya_
not modelled 99.3 17 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
80d1ka9f_
not modelled 99.3 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
81d1xm3a_
not modelled 99.3 14 Fold:TIM beta/alpha-barrel
Superfamily:ThiG-like
Family:ThiG-like
82c2h6rG_
not modelled 99.2 11 PDB header:isomerase
Chain: G: PDB Molecule:triosephosphate isomerase;
PDBTitle: crystal structure of triosephosphate isomerase (tim) from2 methanocaldococcus jannaschii
83c2bdqA_
not modelled 99.2 15 PDB header:metal transport
Chain: A: PDB Molecule:copper homeostasis protein cutc;
PDBTitle: crystal structure of the putative copper homeostasis2 protein cutc from streptococcus agalactiae, northeast3 strucural genomics target sar15.
84d1thfd_
not modelled 99.2 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
85d1znna1
not modelled 99.2 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:PdxS-like
86c1znnF_
not modelled 99.2 14 PDB header:biosynthetic protein
Chain: F: PDB Molecule:plp synthase;
PDBTitle: structure of the synthase subunit of plp synthase
87c2y85D_
not modelled 99.1 18 PDB header:isomerase
Chain: D: PDB Molecule:phosphoribosyl isomerase a;
PDBTitle: crystal structure of mycobacterium tuberculosis phosphoribosyl2 isomerase with bound rcdrp
88c3ceuA_
not modelled 99.1 13 PDB header:transferase
Chain: A: PDB Molecule:thiamine phosphate pyrophosphorylase;
PDBTitle: crystal structure of thiamine phosphate pyrophosphorylase2 (bt_0647) from bacteroides thetaiotaomicron. northeast3 structural genomics consortium target btr268
89d1zfja1
not modelled 99.0 15 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
90d1vzwa1
not modelled 99.0 17 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
91c2cdh1_
not modelled 98.9 14 PDB header:transferase
Chain: 1: PDB Molecule:enoyl reductase;
PDBTitle: architecture of the thermomyces lanuginosus fungal fatty2 acid synthase at 5 angstrom resolution.
92c2gjlA_
not modelled 98.9 9 PDB header:oxidoreductase
Chain: A: PDB Molecule:hypothetical protein pa1024;
PDBTitle: crystal structure of 2-nitropropane dioxygenase
93d1o4ua1
not modelled 98.9 17 Fold:TIM beta/alpha-barrel
Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like
Family:NadC C-terminal domain-like
94c2z6jB_
not modelled 98.9 12 PDB header:oxidoreductase
Chain: B: PDB Molecule:trans-2-enoyl-acp reductase ii;
PDBTitle: crystal structure of s. pneumoniae enoyl-acyl carrier2 protein reductase (fabk) in complex with an inhibitor
95c3khjE_
not modelled 98.8 16 PDB header:oxidoreductase
Chain: E: PDB Molecule:inosine-5-monophosphate dehydrogenase;
PDBTitle: c. parvum inosine monophosphate dehydrogenase bound by inhibitor c64
96c1zfjA_
not modelled 98.8 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine monophosphate dehydrogenase;
PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes
97c3bo9B_
not modelled 98.8 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative nitroalkan dioxygenase;
PDBTitle: crystal structure of putative nitroalkan dioxygenase (tm0800) from2 thermotoga maritima at 2.71 a resolution
98d1vrda1
not modelled 98.7 14 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
99c3ffsC_
not modelled 98.7 15 PDB header:oxidoreductase
Chain: C: PDB Molecule:inosine-5-monophosphate dehydrogenase;
PDBTitle: the crystal structure of cryptosporidium parvum inosine-5'-2 monophosphate dehydrogenase
100c3r2gA_
not modelled 98.7 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine 5'-monophosphate dehydrogenase;
PDBTitle: crystal structure of inosine 5' monophosphate dehydrogenase from2 legionella pneumophila
101d1eepa_
not modelled 98.7 12 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
102c2a7rD_
not modelled 98.7 9 PDB header:oxidoreductase
Chain: D: PDB Molecule:gmp reductase 2;
PDBTitle: crystal structure of human guanosine monophosphate2 reductase 2 (gmpr2)
103d1goxa_
not modelled 98.6 14 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
104d1p0ka_
not modelled 98.6 12 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
105c2zbtB_
not modelled 98.6 12 PDB header:lyase
Chain: B: PDB Molecule:pyridoxal biosynthesis lyase pdxs;
PDBTitle: crystal structure of pyridoxine biosynthesis protein from thermus2 thermophilus hb8
106d1to3a_
not modelled 98.6 11 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
107c1jcnA_
not modelled 98.6 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine monophosphate dehydrogenase i;
PDBTitle: binary complex of human type-i inosine monophosphate dehydrogenase2 with 6-cl-imp
108c3gr7A_
not modelled 98.6 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadph dehydrogenase;
PDBTitle: structure of oye from geobacillus kaustophilus, hexagonal2 crystal form
109c3ivuB_
not modelled 98.6 15 PDB header:transferase
Chain: B: PDB Molecule:homocitrate synthase, mitochondrial;
PDBTitle: homocitrate synthase lys4 bound to 2-og
110d1pvna1
not modelled 98.6 12 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
111d1v5xa_
not modelled 98.5 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
112d1vhna_
not modelled 98.5 19 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
113d1gtea2
not modelled 98.5 17 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
114d1qapa1
not modelled 98.5 13 Fold:TIM beta/alpha-barrel
Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like
Family:NadC C-terminal domain-like
115d1jr1a1
not modelled 98.5 17 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
116d1jcna1
not modelled 98.5 11 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
117d1tb3a1
not modelled 98.5 12 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
118c1vrdA_
not modelled 98.5 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine-5'-monophosphate dehydrogenase;
PDBTitle: crystal structure of inosine-5'-monophosphate dehydrogenase (tm1347)2 from thermotoga maritima at 2.18 a resolution
119c3bw2A_
not modelled 98.5 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-nitropropane dioxygenase;
PDBTitle: crystal structures and site-directed mutagenesis study of nitroalkane2 oxidase from streptomyces ansochromogenes
120d1nsja_
not modelled 98.5 9 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0