PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2qcnA_

Fold library id	PDB Header	Molecule	Title
c2qcnA_	PDB header: lyase	Chain: A: PDB Molecule: uridine 5'-monophosphate synthase;	PDBTitle: covalent complex of the orotidine-5'-monophosphate2 decarboxylase domain of human ump synthase with 6-iodo-ump

Links to external resources
Added to library: Tue Mar 16 12:31:19 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence M E L S F G A R A E L P R I H P V A S K L L R L M Q K K E T N L C L S A D V S L A R E L L Q L A D A L G P S I C M L K T H V D I L N D F T L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
T T
T
S
G G G
S
G G G
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence D V M K E L I T L A K C H E F L I F E D R K F A D I G N T V K K Q Y E G G I F K I A S W A D L V N A H V V P G S G V V K G L Q E V G L P L H

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S
T T T
G G G T
S S T T
T T T T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence R G C L L I A E M S S T G S L A T G D Y T R A A V R M A E E H S E F V V G F I S G S R V S M K P E F L H L T P G V Q L E A G G D N L G Q Q Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S T T
T T T T T T
S S
T T S
S B
S S S
B
T T S
B

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . .

Sequence N S P Q E V I G K R G S D I I I V G R G I I S A A D R L E A A E M Y R K A A W E A Y L S R L G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) B
T T S
S S T S S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

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Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	M	E	L	S	F	G	A	R	A	E	L	P	R	I	H	P	V	A	S	K	L	L	R	L	M	Q	K	K	E	T	N	L	C	L	S	A	D	V	S	L	A	R	E	L	L	Q	L	A	D	A	L	G	P	S	I	C	M	L	K	T	H	V	D	I	L	N	D	F	T	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									T	T		T	T																T										S													G	G	G		S						G	G	G		T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	D	V	M	K	E	L	I	T	L	A	K	C	H	E	F	L	I	F	E	D	R	K	F	A	D	I	G	N	T	V	K	K	Q	Y	E	G	G	I	F	K	I	A	S	W	A	D	L	V	N	A	H	V	V	P	G	S	G	V	V	K	G	L	Q	E	V	G	L	P	L	H
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)														T											S												T	T	T		G	G	G	T		S						S	T	T		T											T	T	T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	R	G	C	L	L	I	A	E	M	S	S	T	G	S	L	A	T	G	D	Y	T	R	A	A	V	R	M	A	E	E	H	S	E	F	V	V	G	F	I	S	G	S	R	V	S	M	K	P	E	F	L	H	L	T	P	G	V	Q	L	E	A	G	G	D	N	L	G	Q	Q	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										S	S	T	T					T												T	T	T	T	T							S	S						T	T	S						S	B		S	S	S		B		T	T	S		B
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.
Sequence	N	S	P	Q	E	V	I	G	K	R	G	S	D	I	I	I	V	G	R	G	I	I	S	A	A	D	R	L	E	A	A	E	M	Y	R	K	A	A	W	E	A	Y	L	S	R	L	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	B							T	T	S			S					S					T	S	S