Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP37678
DateThu Jan 5 11:56:52 GMT 2012
Unique Job IDe94863cc99d600be

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1q6oa_
Top template information
Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
Confidence and coverage
Confidence:100.0% Coverage: 96%
212 residues ( 96% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MSRPLLQLALDHSSLEAAQRDVTLLKDSVDIVEAGTILCLNEGLGAVKALREQCPDKIIV
Secondary structure 
SS confidence 
Disorder  ????
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  ADWKVADAGETLAQQAFGAGANWMTIICAAPLATVEKGHAMAQRCGGEIQIELFGNWTLD
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  DARDWHRIGVRQAIYHRGRDAQASGQQWGEADLARMKALSDIGLELSITGGITPADLPLF
Secondary structure 
SS confidence 
Disorder 
?????????
???
??
Disorder confidence 
 
   .........190.........200.........210.........220
Sequence  KDIRVKAFIAGRALAGAANPAQVAGDFHAQIDAIWGGARA
Secondary structure 
SS confidence 
Disorder 
?
?
?????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1q6o chain A

3D model

Region: 4 - 215
Aligned: 212
Modelled: 212
Confidence: 100.0%
Identity: 45%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Decarboxylase

Phyre2

PDB 3jr2 chain D

3D model

Region: 3 - 215
Aligned: 212
Modelled: 213
Confidence: 100.0%
Identity: 47%
PDB header:biosynthetic protein
Chain: D: PDB Molecule:hexulose-6-phosphate synthase sgbh;
PDBTitle: x-ray crystal structure of the mg-bound 3-keto-l-gulonate-6-phosphate2 decarboxylase from vibrio cholerae o1 biovar el tor str. n16961

Phyre2

PDB 3exs chain B

3D model

Region: 2 - 216
Aligned: 208
Modelled: 215
Confidence: 100.0%
Identity: 45%
PDB header:lyase
Chain: B: PDB Molecule:rmpd (hexulose-6-phosphate synthase);
PDBTitle: crystal structure of kgpdc from streptococcus mutans in2 complex with d-r5p

Phyre2

PDB 3ajx chain A

3D model

Region: 1 - 211
Aligned: 204
Modelled: 207
Confidence: 100.0%
Identity: 33%
PDB header:lyase
Chain: A: PDB Molecule:3-hexulose-6-phosphate synthase;
PDBTitle: crystal structure of 3-hexulose-6-phosphate synthase

Phyre2

PDB 3f4w chain A

3D model

Region: 1 - 215
Aligned: 210
Modelled: 212
Confidence: 100.0%
Identity: 28%
PDB header:synthase, lyase
Chain: A: PDB Molecule:putative hexulose 6 phosphate synthase;
PDBTitle: the 1.65a crystal structure of 3-hexulose-6-phosphate2 synthase from salmonella typhimurium

Phyre2

PDB 3ru6 chain C

3D model

Region: 5 - 212
Aligned: 206
Modelled: 208
Confidence: 100.0%
Identity: 18%
PDB header:lyase
Chain: C: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: 1.8 angstrom resolution crystal structure of orotidine 5'-phosphate2 decarboxylase (pyrf) from campylobacter jejuni subsp. jejuni nctc3 11168

Phyre2

PDB 3tr2 chain A

3D model

Region: 4 - 211
Aligned: 206
Modelled: 207
Confidence: 100.0%
Identity: 17%
PDB header:lyase
Chain: A: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: structure of a orotidine 5'-phosphate decarboxylase (pyrf) from2 coxiella burnetii

Phyre2

PDB 1eix chain A

3D model

Region: 1 - 212
Aligned: 210
Modelled: 212
Confidence: 100.0%
Identity: 15%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Decarboxylase

Phyre2

PDB 1dbt chain A

3D model

Region: 1 - 214
Aligned: 212
Modelled: 214
Confidence: 100.0%
Identity: 16%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Decarboxylase

Phyre2

PDB 3tfx chain B

3D model

Region: 3 - 212
Aligned: 207
Modelled: 210
Confidence: 100.0%
Identity: 18%
PDB header:lyase
Chain: B: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: crystal structure of orotidine 5'-phosphate decarboxylase from2 lactobacillus acidophilus

Phyre2

PDB 1km4 chain A

3D model

Region: 1 - 211
Aligned: 205
Modelled: 210
Confidence: 100.0%
Identity: 25%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Decarboxylase

Phyre2

PDB 3ldv chain B

3D model

Region: 4 - 211
Aligned: 206
Modelled: 208
Confidence: 100.0%
Identity: 17%
PDB header:lyase
Chain: B: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: 1.77 angstrom resolution crystal structure of orotidine 5'-2 phosphate decarboxylase from vibrio cholerae o1 biovar3 eltor str. n16961

Phyre2

PDB 1dvj chain A

3D model

Region: 1 - 213
Aligned: 207
Modelled: 211
Confidence: 100.0%
Identity: 25%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Decarboxylase

Phyre2

PDB 2yyt chain A

3D model

Region: 6 - 212
Aligned: 199
Modelled: 201
Confidence: 100.0%
Identity: 18%
PDB header:lyase
Chain: A: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: crystal structure of uncharacterized conserved protein from2 geobacillus kaustophilus

Phyre2

PDB 2qcn chain A

3D model

Region: 2 - 219
Aligned: 207
Modelled: 215
Confidence: 100.0%
Identity: 17%
PDB header:lyase
Chain: A: PDB Molecule:uridine 5'-monophosphate synthase;
PDBTitle: covalent complex of the orotidine-5'-monophosphate decarboxylase2 domain of human ump synthase with 6-iodo-ump

Phyre2

PDB 3bvj chain A

3D model

Region: 2 - 219
Aligned: 207
Modelled: 215
Confidence: 100.0%
Identity: 17%
PDB header:lyase
Chain: A: PDB Molecule:uridine 5'-monophosphate synthase;
PDBTitle: crystal structure of human orotidine 5'-monophosphate decarboxylase2 complexed with xmp

Phyre2

PDB 2czd chain A domain 1

3D model

Region: 5 - 212
Aligned: 201
Modelled: 204
Confidence: 100.0%
Identity: 21%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Decarboxylase

Phyre2

PDB 1dqw chain A

3D model

Region: 2 - 218
Aligned: 210
Modelled: 217
Confidence: 100.0%
Identity: 16%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Decarboxylase

Phyre2

PDB 3qw3 chain B

3D model

Region: 1 - 217
Aligned: 214
Modelled: 217
Confidence: 100.0%
Identity: 19%
PDB header:transferase, lyase
Chain: B: PDB Molecule:orotidine-5-phosphate decarboxylase/orotate
PDBTitle: structure of leishmania donovani omp decarboxylase

Phyre2

PDB 1vqt chain A domain 1

3D model

Region: 3 - 209
Aligned: 185
Modelled: 207
Confidence: 100.0%
Identity: 17%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Decarboxylase

Phyre2
1
d1q6oa_
2
c3jr2D_
3
c3exsB_
4
c3ajxA_
5
c3f4wA_
6
c3ru6C_
7
c3tr2A_
8
d1eixa_
9
d1dbta_
10
c3tfxB_
11
d1km4a_
12
c3ldvB_
13
d1dvja_
14
c2yytA_
15
c2qcnA_
16
c3bvjA_
17
d2czda1
18
d1dqwa_
19
c3qw3B_
20
d1vqta1
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
438
439
440
441
442
443
444
445
446
447
448
449
450
451
452
453
454
455
456
457
458
459
460
461
462
463
464
465
466
467
468
469
470
471
472
473
474
475
476
477
478
479
480
481
482
483
484
485
486
487
488
489
490
491
492
493
494
495
496
497
498
499



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1q6oa_
100.0 45 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
2c3jr2D_
100.0 47 PDB header:biosynthetic protein
Chain: D: PDB Molecule:hexulose-6-phosphate synthase sgbh;
PDBTitle: x-ray crystal structure of the mg-bound 3-keto-l-gulonate-6-phosphate2 decarboxylase from vibrio cholerae o1 biovar el tor str. n16961
3c3exsB_
100.0 45 PDB header:lyase
Chain: B: PDB Molecule:rmpd (hexulose-6-phosphate synthase);
PDBTitle: crystal structure of kgpdc from streptococcus mutans in2 complex with d-r5p
4c3ajxA_
100.0 33 PDB header:lyase
Chain: A: PDB Molecule:3-hexulose-6-phosphate synthase;
PDBTitle: crystal structure of 3-hexulose-6-phosphate synthase
5c3f4wA_
100.0 28 PDB header:synthase, lyase
Chain: A: PDB Molecule:putative hexulose 6 phosphate synthase;
PDBTitle: the 1.65a crystal structure of 3-hexulose-6-phosphate2 synthase from salmonella typhimurium
6c3ru6C_
100.0 18 PDB header:lyase
Chain: C: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: 1.8 angstrom resolution crystal structure of orotidine 5'-phosphate2 decarboxylase (pyrf) from campylobacter jejuni subsp. jejuni nctc3 11168
7c3tr2A_
100.0 17 PDB header:lyase
Chain: A: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: structure of a orotidine 5'-phosphate decarboxylase (pyrf) from2 coxiella burnetii
8d1eixa_
100.0 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
9d1dbta_
100.0 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
10c3tfxB_
100.0 18 PDB header:lyase
Chain: B: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: crystal structure of orotidine 5'-phosphate decarboxylase from2 lactobacillus acidophilus
11d1km4a_
100.0 25 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
12c3ldvB_
100.0 17 PDB header:lyase
Chain: B: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: 1.77 angstrom resolution crystal structure of orotidine 5'-2 phosphate decarboxylase from vibrio cholerae o1 biovar3 eltor str. n16961
13d1dvja_
100.0 25 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
14c2yytA_
100.0 18 PDB header:lyase
Chain: A: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: crystal structure of uncharacterized conserved protein from2 geobacillus kaustophilus
15c2qcnA_
100.0 17 PDB header:lyase
Chain: A: PDB Molecule:uridine 5'-monophosphate synthase;
PDBTitle: covalent complex of the orotidine-5'-monophosphate decarboxylase2 domain of human ump synthase with 6-iodo-ump
16c3bvjA_
100.0 17 PDB header:lyase
Chain: A: PDB Molecule:uridine 5'-monophosphate synthase;
PDBTitle: crystal structure of human orotidine 5'-monophosphate decarboxylase2 complexed with xmp
17d2czda1
100.0 21 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
18d1dqwa_
100.0 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
19c3qw3B_
100.0 19 PDB header:transferase, lyase
Chain: B: PDB Molecule:orotidine-5-phosphate decarboxylase/orotate
PDBTitle: structure of leishmania donovani omp decarboxylase
20d1vqta1
100.0 17 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
21c3ct7E_
not modelled 100.0 17 PDB header:isomerase
Chain: E: PDB Molecule:d-allulose-6-phosphate 3-epimerase;
PDBTitle: crystal structure of d-allulose 6-phosphate 3-epimerase2 from escherichia coli k-12
22d1losc_
not modelled 100.0 23 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
23c3qc3B_
not modelled 100.0 16 PDB header:isomerase
Chain: B: PDB Molecule:d-ribulose-5-phosphate-3-epimerase;
PDBTitle: crystal structure of a d-ribulose-5-phosphate-3-epimerase (np_954699)2 from homo sapiens at 2.20 a resolution
24d1tqxa_
not modelled 100.0 11 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
25d1h1ya_
not modelled 100.0 17 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
26c3cu2A_
not modelled 100.0 14 PDB header:isomerase
Chain: A: PDB Molecule:ribulose-5-phosphate 3-epimerase;
PDBTitle: crystal structure of ribulose-5-phosphate 3-epimerase (yp_718263.1)2 from haemophilus somnus 129pt at 1.91 a resolution
27d1qopa_
not modelled 100.0 18 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
28c3qw4B_
not modelled 100.0 22 PDB header:transferase, lyase
Chain: B: PDB Molecule:ump synthase;
PDBTitle: structure of leishmania donovani ump synthase
29c3inpA_
not modelled 99.9 20 PDB header:isomerase
Chain: A: PDB Molecule:d-ribulose-phosphate 3-epimerase;
PDBTitle: 2.05 angstrom resolution crystal structure of d-ribulose-phosphate 3-2 epimerase from francisella tularensis.
30d1rpxa_
not modelled 99.9 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
31c3thaB_
not modelled 99.9 11 PDB header:lyase
Chain: B: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: tryptophan synthase subunit alpha from campylobacter jejuni.
32c3navB_
not modelled 99.9 18 PDB header:lyase
Chain: B: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: crystal structure of an alpha subunit of tryptophan synthase from2 vibrio cholerae o1 biovar el tor str. n16961
33d2flia1
not modelled 99.9 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
34c3l52A_
not modelled 99.9 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: crystal structure of putative orotidine 5'-phosphate2 decarboxylase from streptomyces avermitilis ma-4680
35d1rd5a_
not modelled 99.9 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
36d2q8za1
not modelled 99.9 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
37d2ffca1
not modelled 99.9 18 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
38c2ekcA_
not modelled 99.9 14 PDB header:lyase
Chain: A: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5
39c3r89A_
not modelled 99.9 16 PDB header:lyase
Chain: A: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: crystal structure of orotidine 5-phosphate decarboxylase from2 anaerococcus prevotii dsm 20548
40d1ujpa_
not modelled 99.9 18 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
41d1geqa_
not modelled 99.9 11 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
42c2fdsA_
not modelled 99.9 16 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:orotidine-monophosphate-decarboxylase;
PDBTitle: crystal structure of plasmodium berghei orotidine 5'-2 monophosphate decarboxylase (ortholog of plasmodium3 falciparum pf10_0225)
43d2fdsa1
not modelled 99.9 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
44d1tqja_
not modelled 99.9 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
45d1xcfa_
not modelled 99.9 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
46c2v82A_
not modelled 99.7 18 PDB header:lyase
Chain: A: PDB Molecule:2-dehydro-3-deoxy-6-phosphogalactonate aldolase;
PDBTitle: kdpgal complexed to kdpgal
47c3gndC_
not modelled 99.7 13 PDB header:lyase
Chain: C: PDB Molecule:aldolase lsrf;
PDBTitle: crystal structure of e. coli lsrf in complex with ribulose-5-phosphate
48d1wbha1
not modelled 99.7 17 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
49d1j5ta_
not modelled 99.7 17 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
50d1ojxa_
not modelled 99.7 13 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
51d1wa3a1
not modelled 99.7 18 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
52d1piia2
not modelled 99.7 10 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
53c3igsB_
not modelled 99.7 18 PDB header:isomerase
Chain: B: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase 2;
PDBTitle: structure of the salmonella enterica n-acetylmannosamine-6-phosphate2 2-epimerase
54d2tpsa_
not modelled 99.7 13 Fold:TIM beta/alpha-barrel
Superfamily:Thiamin phosphate synthase
Family:Thiamin phosphate synthase
55d1vhca_
not modelled 99.7 15 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
56d1xi3a_
not modelled 99.7 13 Fold:TIM beta/alpha-barrel
Superfamily:Thiamin phosphate synthase
Family:Thiamin phosphate synthase
57c3qjaA_
not modelled 99.7 15 PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of the mycobacterium tuberculosis indole-3-glycerol2 phosphate synthase (trpc) in apo form
58c3q58A_
not modelled 99.7 17 PDB header:isomerase
Chain: A: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase;
PDBTitle: structure of n-acetylmannosamine-6-phosphate epimerase from salmonella2 enterica
59c1yadD_
not modelled 99.7 13 PDB header:transcription
Chain: D: PDB Molecule:regulatory protein teni;
PDBTitle: structure of teni from bacillus subtilis
60c2c3zA_
not modelled 99.7 15 PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus
61d1i4na_
not modelled 99.7 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
62d1a53a_
not modelled 99.6 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
63c2qjhH_
not modelled 99.6 11 PDB header:lyase
Chain: H: PDB Molecule:putative aldolase mj0400;
PDBTitle: m. jannaschii adh synthase covalently bound to2 dihydroxyacetone phosphate
64d1vc4a_
not modelled 99.6 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
65c3labA_
not modelled 99.6 20 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative kdpg (2-keto-3-deoxy-6-phosphogluconate)
PDBTitle: crystal structure of a putative kdpg (2-keto-3-deoxy-6-2 phosphogluconate) aldolase from oleispira antarctica
66d1mxsa_
not modelled 99.6 16 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
67d1y0ea_
not modelled 99.6 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:NanE-like
68c3o63B_
not modelled 99.6 17 PDB header:transferase
Chain: B: PDB Molecule:probable thiamine-phosphate pyrophosphorylase;
PDBTitle: crystal structure of thiamin phosphate synthase from mycobacterium2 tuberculosis
69d1yxya1
not modelled 99.6 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:NanE-like
70d1w0ma_
not modelled 99.5 12 Fold:TIM beta/alpha-barrel
Superfamily:Triosephosphate isomerase (TIM)
Family:Triosephosphate isomerase (TIM)
71c3nm3D_
not modelled 99.5 13 PDB header:transferase
Chain: D: PDB Molecule:thiamine biosynthetic bifunctional enzyme;
PDBTitle: the crystal structure of candida glabrata thi6, a bifunctional enzyme2 involved in thiamin biosyhthesis of eukaryotes
72d1wv2a_
not modelled 99.5 15 Fold:TIM beta/alpha-barrel
Superfamily:ThiG-like
Family:ThiG-like
73d1hg3a_
not modelled 99.5 10 Fold:TIM beta/alpha-barrel
Superfamily:Triosephosphate isomerase (TIM)
Family:Triosephosphate isomerase (TIM)
74c2yw3E_
not modelled 99.5 20 PDB header:lyase
Chain: E: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase/2-deydro-3-
PDBTitle: crystal structure analysis of the 4-hydroxy-2-oxoglutarate aldolase/2-2 deydro-3-deoxyphosphogluconate aldolase from tthb1
75c1piiA_
not modelled 99.4 12 PDB header:bifunctional(isomerase and synthase)
Chain: A: PDB Molecule:n-(5'phosphoribosyl)anthranilate isomerase;
PDBTitle: three-dimensional structure of the bifunctional enzyme2 phosphoribosylanthranilate isomerase:3 indoleglycerolphosphate synthase from escherichia coli4 refined at 2.0 angstroms resolution
76c2htmB_
not modelled 99.4 15 PDB header:biosynthetic protein
Chain: B: PDB Molecule:thiazole biosynthesis protein thig;
PDBTitle: crystal structure of ttha0676 from thermus thermophilus hb8
77d2f6ua1
not modelled 99.3 14 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
78d1viza_
not modelled 99.3 13 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
79d1xm3a_
not modelled 99.3 14 Fold:TIM beta/alpha-barrel
Superfamily:ThiG-like
Family:ThiG-like
80d1h5ya_
not modelled 99.3 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
81d1ka9f_
not modelled 99.3 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
82d1thfd_
not modelled 99.2 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
83c2bdqA_
not modelled 99.2 12 PDB header:metal transport
Chain: A: PDB Molecule:copper homeostasis protein cutc;
PDBTitle: crystal structure of the putative copper homeostasis2 protein cutc from streptococcus agalactiae, northeast3 strucural genomics target sar15.
84c2h6rG_
not modelled 99.2 14 PDB header:isomerase
Chain: G: PDB Molecule:triosephosphate isomerase;
PDBTitle: crystal structure of triosephosphate isomerase (tim) from2 methanocaldococcus jannaschii
85d1znna1
not modelled 99.2 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:PdxS-like
86c1znnF_
not modelled 99.1 14 PDB header:biosynthetic protein
Chain: F: PDB Molecule:plp synthase;
PDBTitle: structure of the synthase subunit of plp synthase
87c2y85D_
not modelled 99.1 12 PDB header:isomerase
Chain: D: PDB Molecule:phosphoribosyl isomerase a;
PDBTitle: crystal structure of mycobacterium tuberculosis phosphoribosyl2 isomerase with bound rcdrp
88c3ceuA_
not modelled 99.1 11 PDB header:transferase
Chain: A: PDB Molecule:thiamine phosphate pyrophosphorylase;
PDBTitle: crystal structure of thiamine phosphate pyrophosphorylase2 (bt_0647) from bacteroides thetaiotaomicron. northeast3 structural genomics consortium target btr268
89d1zfja1
not modelled 99.0 18 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
90d1o4ua1
not modelled 98.9 17 Fold:TIM beta/alpha-barrel
Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like
Family:NadC C-terminal domain-like
91c2z6jB_
not modelled 98.9 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:trans-2-enoyl-acp reductase ii;
PDBTitle: crystal structure of s. pneumoniae enoyl-acyl carrier2 protein reductase (fabk) in complex with an inhibitor
92c2gjlA_
not modelled 98.9 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:hypothetical protein pa1024;
PDBTitle: crystal structure of 2-nitropropane dioxygenase
93d1vzwa1
not modelled 98.8 19 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
94c2cdh1_
not modelled 98.8 17 PDB header:transferase
Chain: 1: PDB Molecule:enoyl reductase;
PDBTitle: architecture of the thermomyces lanuginosus fungal fatty2 acid synthase at 5 angstrom resolution.
95d1vrda1
not modelled 98.8 14 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
96c3bo9B_
not modelled 98.8 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative nitroalkan dioxygenase;
PDBTitle: crystal structure of putative nitroalkan dioxygenase (tm0800) from2 thermotoga maritima at 2.71 a resolution
97c1zfjA_
not modelled 98.8 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine monophosphate dehydrogenase;
PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes
98c3khjE_
not modelled 98.8 14 PDB header:oxidoreductase
Chain: E: PDB Molecule:inosine-5-monophosphate dehydrogenase;
PDBTitle: c. parvum inosine monophosphate dehydrogenase bound by inhibitor c64
99c3ffsC_
not modelled 98.8 14 PDB header:oxidoreductase
Chain: C: PDB Molecule:inosine-5-monophosphate dehydrogenase;
PDBTitle: the crystal structure of cryptosporidium parvum inosine-5'-2 monophosphate dehydrogenase
100d1eepa_
not modelled 98.7 12 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
101d1p0ka_
not modelled 98.7 13 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
102c3r2gA_
not modelled 98.6 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine 5'-monophosphate dehydrogenase;
PDBTitle: crystal structure of inosine 5' monophosphate dehydrogenase from2 legionella pneumophila
103d1gtea2
not modelled 98.6 16 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
104d1jcna1
not modelled 98.6 15 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
105c1jcnA_
not modelled 98.6 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine monophosphate dehydrogenase i;
PDBTitle: binary complex of human type-i inosine monophosphate dehydrogenase2 with 6-cl-imp
106d1qpoa1
not modelled 98.6 15 Fold:TIM beta/alpha-barrel
Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like
Family:NadC C-terminal domain-like
107d1qapa1
not modelled 98.5 15 Fold:TIM beta/alpha-barrel
Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like
Family:NadC C-terminal domain-like
108d1jr1a1
not modelled 98.5 13 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
109c3gr7A_
not modelled 98.5 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadph dehydrogenase;
PDBTitle: structure of oye from geobacillus kaustophilus, hexagonal2 crystal form
110c3ivuB_
not modelled 98.5 13 PDB header:transferase
Chain: B: PDB Molecule:homocitrate synthase, mitochondrial;
PDBTitle: homocitrate synthase lys4 bound to 2-og
111d1goxa_
not modelled 98.5 17 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
112c2a7rD_
not modelled 98.5 13 PDB header:oxidoreductase
Chain: D: PDB Molecule:gmp reductase 2;
PDBTitle: crystal structure of human guanosine monophosphate2 reductase 2 (gmpr2)
113c1vrdA_
not modelled 98.5 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine-5'-monophosphate dehydrogenase;
PDBTitle: crystal structure of inosine-5'-monophosphate dehydrogenase (tm1347)2 from thermotoga maritima at 2.18 a resolution
114c2zyfA_
not modelled 98.5 10 PDB header:transferase
Chain: A: PDB Molecule:homocitrate synthase;
PDBTitle: crystal structure of homocitrate synthase from thermus thermophilus2 complexed with magnesuim ion and alpha-ketoglutarate
115d1tb3a1
not modelled 98.5 16 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
116c2zrvC_
not modelled 98.5 13 PDB header:isomerase
Chain: C: PDB Molecule:isopentenyl-diphosphate delta-isomerase;
PDBTitle: crystal structure of sulfolobus shibatae isopentenyl2 diphosphate isomerase in complex with reduced fmn.
117c2w6rA_
not modelled 98.5 12 PDB header:lyase
Chain: A: PDB Molecule:imidazole glycerol phosphate synthase subunit
PDBTitle: crystal structure of an artificial (ba)8-barrel protein2 designed from identical half barrels
118d1to3a_
not modelled 98.4 15 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
119c1ypfB_
not modelled 98.4 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:gmp reductase;
PDBTitle: crystal structure of guac (ba5705) from bacillus anthracis at 1.8 a2 resolution
120d1z41a1
not modelled 98.4 18 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0