Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	N	N	S	Q	L	L	M	P	R	E	K	M	L	K	F	G	I	S	A	L	T	D	V	E	L	L	A	L	F	L	R	T	G	T	R	G	K	D	V	L	T	L	A	K	E	M	L	E	N	F	G	S	L	Y	G	L	L	T
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	E	Y	E	Q	F	S	G	V	H	G	I	G	V	A	K	F	A	Q	L	K	G	I	A	E	L	A	R	R	Y	Y	N	V	R	M	R	E	E	S	P	L	L	S	P	E	M	T	R	E	F	L	Q	S	Q	L	T	G	E	E	R
Secondary structure
SS confidence
Disorder																																		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		E	I	F	M	V	I	F	L	D	S	Q	H	R	V	I	T	H	R	R	L	F	S	G	T	L	N	H	V	E	V	H	P	R	E	I	I	R	E	A	I	K	I	N	A	S	A	L	I	L	A	H	N	H	P	S	G	C	A	E	P
Secondary structure
SS confidence
Disorder																																																											?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.
Sequence		S	K	A	D	K	L	I	T	E	R	I	I	K	S	C	Q	F	M	D	L	R	V	L	D	H	I	V	I	G	R	G	E	Y	V	S	F	A	E	R	G	W	I
Secondary structure
SS confidence
Disorder																																							?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2qlc chain C Region: 99 - 222 Aligned: 124 Modelled: 124 Confidence: 100.0% Identity: 31% PDB header:dna binding protein Chain: C: PDB Molecule:dna repair protein radc homolog; PDBTitle: the crystal structure of dna repair protein radc from chlorobium2 tepidum tls Phyre2 PDB 2bgw chain A domain 1 Region: 22 - 85 Aligned: 63 Modelled: 64 Confidence: 98.2% Identity: 32% Fold: SAM domain-like Superfamily: RuvA domain 2-like Family: Hef domain-like Phyre2 PDB 3c1z chain A Region: 1 - 85 Aligned: 85 Modelled: 85 Confidence: 98.0% Identity: 14% PDB header:dna binding protein Chain: A: PDB Molecule:dna integrity scanning protein disa; PDBTitle: structure of the ligand-free form of a bacterial dna damage2 sensor protein Phyre2 PDB 1x2i chain A domain 1 Region: 21 - 85 Aligned: 63 Modelled: 65 Confidence: 98.0% Identity: 29% Fold: SAM domain-like Superfamily: RuvA domain 2-like Family: Hef domain-like Phyre2 PDB 2a1j chain B domain 1 Region: 34 - 85 Aligned: 51 Modelled: 52 Confidence: 97.8% Identity: 25% Fold: SAM domain-like Superfamily: RuvA domain 2-like Family: Hef domain-like Phyre2 PDB 2bhn chain D Region: 23 - 85 Aligned: 62 Modelled: 63 Confidence: 97.7% Identity: 32% PDB header:hydrolase Chain: D: PDB Molecule:xpf endonuclease; PDBTitle: xpf from aeropyrum pernix Phyre2 PDB 1kft chain A Region: 44 - 84 Aligned: 41 Modelled: 41 Confidence: 97.6% Identity: 22% PDB header:dna binding protein Chain: A: PDB Molecule:excinuclease abc subunit c; PDBTitle: solution structure of the c-terminal domain of uvrc from e-2 coli Phyre2 PDB 1kft chain A Region: 44 - 84 Aligned: 41 Modelled: 41 Confidence: 97.6% Identity: 22% Fold: SAM domain-like Superfamily: RuvA domain 2-like Family: Excinuclease UvrC C-terminal domain Phyre2 PDB 1dgs chain A domain 1 Region: 26 - 85 Aligned: 59 Modelled: 60 Confidence: 97.2% Identity: 22% Fold: SAM domain-like Superfamily: RuvA domain 2-like Family: NAD+-dependent DNA ligase, domain 3 Phyre2 PDB 2owo chain A Region: 27 - 104 Aligned: 77 Modelled: 78 Confidence: 96.8% Identity: 19% PDB header:ligase/dna Chain: A: PDB Molecule:dna ligase; PDBTitle: last stop on the road to repair: structure of e.coli dna ligase bound2 to nicked dna-adenylate Phyre2 PDB 1dgs chain B Region: 27 - 85 Aligned: 58 Modelled: 59 Confidence: 96.8% Identity: 22% PDB header:ligase Chain: B: PDB Molecule:dna ligase; PDBTitle: crystal structure of nad+-dependent dna ligase from t.2 filiformis Phyre2 PDB 2i1q chain A domain 1 Region: 44 - 83 Aligned: 40 Modelled: 40 Confidence: 96.7% Identity: 15% Fold: SAM domain-like Superfamily: Rad51 N-terminal domain-like Family: DNA repair protein Rad51, N-terminal domain Phyre2 PDB 2nrz chain B Region: 45 - 84 Aligned: 39 Modelled: 40 Confidence: 96.7% Identity: 26% PDB header:hydrolase Chain: B: PDB Molecule:uvrabc system protein c; PDBTitle: crystal structure of the c-terminal half of uvrc bound to2 its catalytic divalent cation Phyre2 PDB 1oi0 chain A Region: 104 - 220 Aligned: 90 Modelled: 100 Confidence: 96.6% Identity: 18% Fold: Cytidine deaminase-like Superfamily: JAB1/MPN domain Family: JAB1/MPN domain Phyre2 PDB 1v9p chain B Region: 27 - 84 Aligned: 57 Modelled: 57 Confidence: 96.5% Identity: 23% PDB header:ligase Chain: B: PDB Molecule:dna ligase; PDBTitle: crystal structure of nad+-dependent dna ligase Phyre2 PDB 1pzn chain A domain 1 Region: 44 - 83 Aligned: 40 Modelled: 40 Confidence: 96.4% Identity: 15% Fold: SAM domain-like Superfamily: Rad51 N-terminal domain-like Family: DNA repair protein Rad51, N-terminal domain Phyre2 PDB 1szp chain A domain 1 Region: 45 - 83 Aligned: 39 Modelled: 39 Confidence: 96.1% Identity: 18% Fold: SAM domain-like Superfamily: Rad51 N-terminal domain-like Family: DNA repair protein Rad51, N-terminal domain Phyre2 PDB 2aq0 chain A domain 1 Region: 45 - 84 Aligned: 39 Modelled: 40 Confidence: 96.1% Identity: 13% Fold: SAM domain-like Superfamily: RuvA domain 2-like Family: Hef domain-like Phyre2 PDB 1pu6 chain A Region: 19 - 82 Aligned: 64 Modelled: 64 Confidence: 95.7% Identity: 19% Fold: DNA-glycosylase Superfamily: DNA-glycosylase Family: 3-Methyladenine DNA glycosylase III (MagIII) Phyre2 PDB 2kcq chain A Region: 103 - 186 Aligned: 84 Modelled: 84 Confidence: 95.7% Identity: 14% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:mov34/mpn/pad-1 family; PDBTitle: solution structure of protein sru_2040 from salinibacter2 ruber (strain dsm 13855) . northeast structural genomics3 consortium target srr106 Phyre2 PDB 3bzk chain A domain 1 Region: 60 - 110 Aligned: 51 Modelled: 51 Confidence: 78.0% Identity: 6% Fold: SAM domain-like Superfamily: RuvA domain 2-like Family: Tex HhH-containing domain-like Phyre2 1 c2qlcC_ 2 d2bgwa1 3 c3c1zA_ 4 d1x2ia1 5 d2a1jb1 6 c2bhnD_ 7 c1kftA_ 8 d1kfta_ 9 d1dgsa1 10 c2owoA_ 11 c1dgsB_ 12 d2i1qa1 13 c2nrzB_ 14 d1oi0a_ 15 c1v9pB_ 16 d1pzna1 17 d1szpa1 18 d2aq0a1 19 d1pu6a_ 20 c2kcqA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 d3bzka1 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2qlcC_ 100.0 31 PDB header:dna binding protein Chain: C: PDB Molecule:dna repair protein radc homolog; PDBTitle: the crystal structure of dna repair protein radc from chlorobium2 tepidum tls 2 d2bgwa1 98.2 32 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Hef domain-like 3 c3c1zA_ 98.0 14 PDB header:dna binding protein Chain: A: PDB Molecule:dna integrity scanning protein disa; PDBTitle: structure of the ligand-free form of a bacterial dna damage2 sensor protein 4 d1x2ia1 98.0 29 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Hef domain-like 5 d2a1jb1 97.8 25 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Hef domain-like 6 c2bhnD_ 97.7 32 PDB header:hydrolase Chain: D: PDB Molecule:xpf endonuclease; PDBTitle: xpf from aeropyrum pernix 7 c1kftA_ 97.6 22 PDB header:dna binding protein Chain: A: PDB Molecule:excinuclease abc subunit c; PDBTitle: solution structure of the c-terminal domain of uvrc from e-2 coli 8 d1kfta_ 97.6 22 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Excinuclease UvrC C-terminal domain 9 d1dgsa1 97.2 22 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:NAD+-dependent DNA ligase, domain 3 10 c2owoA_ 96.8 19 PDB header:ligase/dna Chain: A: PDB Molecule:dna ligase; PDBTitle: last stop on the road to repair: structure of e.coli dna ligase bound2 to nicked dna-adenylate 11 c1dgsB_ 96.8 22 PDB header:ligase Chain: B: PDB Molecule:dna ligase; PDBTitle: crystal structure of nad+-dependent dna ligase from t.2 filiformis 12 d2i1qa1 96.7 15 Fold:SAM domain-like Superfamily:Rad51 N-terminal domain-like Family:DNA repair protein Rad51, N-terminal domain 13 c2nrzB_ 96.7 26 PDB header:hydrolase Chain: B: PDB Molecule:uvrabc system protein c; PDBTitle: crystal structure of the c-terminal half of uvrc bound to2 its catalytic divalent cation 14 d1oi0a_ 96.6 18 Fold:Cytidine deaminase-like Superfamily:JAB1/MPN domain Family:JAB1/MPN domain 15 c1v9pB_ 96.5 23 PDB header:ligase Chain: B: PDB Molecule:dna ligase; PDBTitle: crystal structure of nad+-dependent dna ligase 16 d1pzna1 96.4 15 Fold:SAM domain-like Superfamily:Rad51 N-terminal domain-like Family:DNA repair protein Rad51, N-terminal domain 17 d1szpa1 96.1 18 Fold:SAM domain-like Superfamily:Rad51 N-terminal domain-like Family:DNA repair protein Rad51, N-terminal domain 18 d2aq0a1 96.1 13 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Hef domain-like 19 d1pu6a_ 95.7 19 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:3-Methyladenine DNA glycosylase III (MagIII) 20 c2kcqA_ 95.7 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:mov34/mpn/pad-1 family; PDBTitle: solution structure of protein sru_2040 from salinibacter2 ruber (strain dsm 13855) . northeast structural genomics3 consortium target srr106 21 d1szpb1 not modelled 95.3 18 Fold:SAM domain-like Superfamily:Rad51 N-terminal domain-like Family:DNA repair protein Rad51, N-terminal domain 22 d1b22a_ not modelled 95.1 15 Fold:SAM domain-like Superfamily:Rad51 N-terminal domain-like Family:DNA repair protein Rad51, N-terminal domain 23 c1b22A_ not modelled 95.1 15 PDB header:dna binding protein Chain: A: PDB Molecule:dna repair protein rad51; PDBTitle: rad51 (n-terminal domain) 24 c1ixrA_ not modelled 95.1 17 PDB header:hydrolase Chain: A: PDB Molecule:holliday junction dna helicase ruva; PDBTitle: ruva-ruvb complex 25 c1hjpA_ not modelled 94.7 19 PDB header:dna recombination Chain: A: PDB Molecule:ruva; PDBTitle: holliday junction binding protein ruva from e. coli 26 c1rrqA_ not modelled 94.2 18 PDB header:hydrolase/dna Chain: A: PDB Molecule:muty; PDBTitle: muty adenine glycosylase in complex with dna containing an2 a:oxog pair 27 d1cuka2 not modelled 93.7 22 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:DNA helicase RuvA subunit, middle domain 28 c2kksA_ not modelled 93.2 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution structure of protein dsy2949 from desulfitobacterium2 hafniense. northeast structural genomics consortium target dhr27 29 d1ixra1 not modelled 92.0 18 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:DNA helicase RuvA subunit, middle domain 30 c2h5xA_ not modelled 91.6 19 PDB header:dna binding protein Chain: A: PDB Molecule:holliday junction atp-dependent dna helicase ruva; PDBTitle: ruva from mycobacterium tuberculosis 31 c1yqmA_ not modelled 91.5 27 PDB header:hydrolase/dna Chain: A: PDB Molecule:n-glycosylase/dna lyase; PDBTitle: catalytically inactive human 8-oxoguanine glycosylase2 crosslinked to 7-deazaguanine containing dna 32 c3n5nX_ not modelled 91.3 14 PDB header:hydrolase Chain: X: PDB Molecule:a/g-specific adenine dna glycosylase; PDBTitle: crystal structure analysis of the catalytic domain and interdomain2 connector of human muty homologue 33 d1ngna_ not modelled 90.4 19 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:Mismatch glycosylase 34 d2noha1 not modelled 89.9 22 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:DNA repair glycosylase, 2 C-terminal domains 35 d2abka_ not modelled 89.8 15 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:Endonuclease III 36 d1rrqa1 not modelled 89.8 16 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:Mismatch glycosylase 37 c1ko9A_ not modelled 89.8 27 PDB header:hydrolase Chain: A: PDB Molecule:8-oxoguanine dna glycosylase; PDBTitle: native structure of the human 8-oxoguanine dna glycosylase2 hogg1 38 c3f10A_ not modelled 89.7 13 PDB header:hydrolase, lyase Chain: A: PDB Molecule:8-oxoguanine-dna-glycosylase; PDBTitle: crystal structure of clostridium acetobutylicum 8-2 oxoguanine dna glycosylase in complex with 8-oxoguanosine 39 d1orna_ not modelled 89.7 15 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:Endonuclease III 40 d1kg2a_ not modelled 89.4 13 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:Mismatch glycosylase 41 d1keaa_ not modelled 89.1 17 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:Mismatch glycosylase 42 c1d8lA_ not modelled 88.7 21 PDB header:gene regulation Chain: A: PDB Molecule:protein (holliday junction dna helicase ruva); PDBTitle: e. coli holliday junction binding protein ruva nh2 region2 lacking domain iii 43 d1lb2b_ not modelled 88.2 10 Fold:SAM domain-like Superfamily:C-terminal domain of RNA polymerase alpha subunit Family:C-terminal domain of RNA polymerase alpha subunit 44 d1z3eb1 not modelled 87.7 20 Fold:SAM domain-like Superfamily:C-terminal domain of RNA polymerase alpha subunit Family:C-terminal domain of RNA polymerase alpha subunit 45 d1doqa_ not modelled 86.6 24 Fold:SAM domain-like Superfamily:C-terminal domain of RNA polymerase alpha subunit Family:C-terminal domain of RNA polymerase alpha subunit 46 d1cooa_ not modelled 85.7 10 Fold:SAM domain-like Superfamily:C-terminal domain of RNA polymerase alpha subunit Family:C-terminal domain of RNA polymerase alpha subunit 47 d1bvsa2 not modelled 85.1 21 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:DNA helicase RuvA subunit, middle domain 48 c2w6rA_ not modelled 84.7 13 PDB header:lyase Chain: A: PDB Molecule:imidazole glycerol phosphate synthase subunit PDBTitle: crystal structure of an artificial (ba)8-barrel protein2 designed from identical half barrels 49 d1u9la_ not modelled 81.6 18 Fold:SAM domain-like Superfamily:Rad51 N-terminal domain-like Family:NusA extra C-terminal domains 50 d1mpga1 not modelled 78.9 13 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:DNA repair glycosylase, 2 C-terminal domains 51 d2axtu1 not modelled 78.6 9 Fold:SAM domain-like Superfamily:PsbU/PolX domain-like Family:PsbU-like 52 c1s5lu_ not modelled 78.6 9 PDB header:photosynthesis Chain: U: PDB Molecule:photosystem ii 12 kda extrinsic protein; PDBTitle: architecture of the photosynthetic oxygen evolving center 53 d3bzka1 78.0 6 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Tex HhH-containing domain-like 54 c3fhgA_ not modelled 76.5 13 PDB header:dna repair, hydrolase, lyase Chain: A: PDB Molecule:n-glycosylase/dna lyase; PDBTitle: crystal structure of sulfolobus solfataricus 8-oxoguanine dna2 glycosylase (ssogg) 55 d2duya1 not modelled 75.5 17 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:ComEA-like 56 d2csba4 not modelled 74.3 21 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Topoisomerase V repeat domain 57 c3s6iA_ not modelled 73.0 19 PDB header:hydrolase/dna Chain: A: PDB Molecule:dna-3-methyladenine glycosylase 1; PDBTitle: schizosaccaromyces pombe 3-methyladenine dna glycosylase (mag1) in2 complex with abasic-dna. 58 c3tdmD_ not modelled 72.9 13 PDB header:de novo protein Chain: D: PDB Molecule:computationally designed two-fold symmetric tim-barrel PDBTitle: computationally designed tim-barrel protein, halfflr 59 d2a1ja1 not modelled 71.5 13 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Hef domain-like 60 d2edua1 not modelled 70.9 20 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:ComEA-like 61 c2yciX_ not modelled 68.1 12 PDB header:transferase Chain: X: PDB Molecule:5-methyltetrahydrofolate corrinoid/iron sulfur protein PDBTitle: methyltransferase native 62 d1d8ba_ not modelled 67.4 12 Fold:SAM domain-like Superfamily:HRDC-like Family:HRDC domain from helicases 63 c3e49A_ not modelled 66.0 20 PDB header:metal binding protein Chain: A: PDB Molecule:uncharacterized protein duf849 with a tim barrel fold; PDBTitle: crystal structure of a prokaryotic domain of unknown function (duf849)2 with a tim barrel fold (bxe_c0966) from burkholderia xenovorans lb4003 at 1.75 a resolution 64 c2jhnB_ not modelled 64.4 20 PDB header:hydrolase Chain: B: PDB Molecule:3-methyladenine dna-glycosylase; PDBTitle: 3-methyladenine dna-glycosylase from archaeoglobus fulgidus 65 d2e1fa1 not modelled 63.4 16 Fold:SAM domain-like Superfamily:HRDC-like Family:HRDC domain from helicases 66 c3n0uB_ not modelled 62.9 21 PDB header:hydrolase, lyase Chain: B: PDB Molecule:probable n-glycosylase/dna lyase; PDBTitle: crystal structure of tm1821, the 8-oxoguanine dna glycosylase of2 thermotoga maritima 67 d2fmpa1 not modelled 59.6 7 Fold:SAM domain-like Superfamily:DNA polymerase beta, N-terminal domain-like Family:DNA polymerase beta, N-terminal domain-like 68 c3jrkG_ not modelled 59.0 21 PDB header:lyase Chain: G: PDB Molecule:tagatose 1,6-diphosphate aldolase 2; PDBTitle: a putative tagatose 1,6-diphosphate aldolase from streptococcus2 pyogenes 69 d2csua1 not modelled 57.0 9 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 70 c2yg8B_ not modelled 54.7 21 PDB header:hydrolase Chain: B: PDB Molecule:dna-3-methyladenine glycosidase ii, putative; PDBTitle: structure of an unusual 3-methyladenine dna glycosylase ii (2 alka) from deinococcus radiodurans 71 d2bcqa1 not modelled 54.6 22 Fold:SAM domain-like Superfamily:DNA polymerase beta, N-terminal domain-like Family:DNA polymerase beta, N-terminal domain-like 72 d1f6ya_ not modelled 52.0 16 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Methyltetrahydrofolate-utiluzing methyltransferases 73 d1jmsa1 not modelled 51.0 19 Fold:SAM domain-like Superfamily:DNA polymerase beta, N-terminal domain-like Family:DNA polymerase beta, N-terminal domain-like 74 d1wuda1 not modelled 50.3 21 Fold:SAM domain-like Superfamily:HRDC-like Family:HRDC domain from helicases 75 d1ka9f_ not modelled 49.6 16 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Histidine biosynthesis enzymes 76 d2csba1 not modelled 49.1 23 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Topoisomerase V repeat domain 77 c3lotC_ not modelled 47.3 25 PDB header:structure genomics, unknown function Chain: C: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of protein of unknown function (np_070038.1) from2 archaeoglobus fulgidus at 1.89 a resolution 78 c3c6cA_ not modelled 44.4 20 PDB header:hydrolase Chain: A: PDB Molecule:3-keto-5-aminohexanoate cleavage enzyme; PDBTitle: crystal structure of a putative 3-keto-5-aminohexanoate cleavage2 enzyme (reut_c6226) from ralstonia eutropha jmp134 at 1.72 a3 resolution 79 d1nzpa_ not modelled 44.2 21 Fold:SAM domain-like Superfamily:DNA polymerase beta, N-terminal domain-like Family:DNA polymerase beta, N-terminal domain-like 80 c3q94B_ not modelled 40.9 16 PDB header:lyase Chain: B: PDB Molecule:fructose-bisphosphate aldolase, class ii; PDBTitle: the crystal structure of fructose 1,6-bisphosphate aldolase from2 bacillus anthracis str. 'ames ancestor' 81 c2bcuA_ not modelled 39.5 21 PDB header:transferase, lyase/dna Chain: A: PDB Molecule:dna polymerase lambda; PDBTitle: dna polymerase lambda in complex with a dna duplex2 containing an unpaired damp and a t:t mismatch 82 d1gvfa_ not modelled 38.9 16 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class II FBP aldolase 83 d1xo1a1 not modelled 38.9 27 Fold:SAM domain-like Superfamily:5' to 3' exonuclease, C-terminal subdomain Family:5' to 3' exonuclease, C-terminal subdomain 84 c3op1A_ not modelled 38.6 15 PDB header:transferase Chain: A: PDB Molecule:macrolide-efflux protein; PDBTitle: crystal structure of macrolide-efflux protein sp_1110 from2 streptococcus pneumoniae 85 c3e02A_ not modelled 38.4 16 PDB header:metal binding protein Chain: A: PDB Molecule:uncharacterized protein duf849; PDBTitle: crystal structure of a duf849 family protein (bxe_c0271) from2 burkholderia xenovorans lb400 at 1.90 a resolution 86 d2odgc1 not modelled 38.2 27 Fold:LEM/SAP HeH motif Superfamily:LEM domain Family:LEM domain 87 d1oxja2 not modelled 37.9 12 Fold:alpha-alpha superhelix Superfamily:ARM repeat Family:PHAT domain 88 c1nomA_ not modelled 37.8 28 PDB header:nucleotidyltransferase Chain: A: PDB Molecule:dna polymerase beta; PDBTitle: dna polymerase beta (pol b) (e.c.2.7.7.7), 31-kd domain; soaked in the2 presence of mncl2 (5 millimolar) 89 c3kntC_ not modelled 37.2 14 PDB header:hydrolase, lyase/dna Chain: C: PDB Molecule:n-glycosylase/dna lyase; PDBTitle: crystal structure of methanocaldococcus jannaschii 8-2 oxoguanine glycosylase/lyase in complex with 15mer dna3 containing 8-oxoguanine 90 c1wcnA_ not modelled 36.5 17 PDB header:rna-binding protein Chain: A: PDB Molecule:transcription elongation protein nusa; PDBTitle: nmr structure of the carboxyterminal domains of escherichia2 coli nusa 91 c2csdB_ not modelled 36.4 50 PDB header:isomerase Chain: B: PDB Molecule:topoisomerase v; PDBTitle: crystal structure of topoisomerase v (61 kda fragment) 92 c3c52B_ not modelled 35.7 14 PDB header:lyase Chain: B: PDB Molecule:fructose-bisphosphate aldolase; PDBTitle: class ii fructose-1,6-bisphosphate aldolase from2 helicobacter pylori in complex with3 phosphoglycolohydroxamic acid, a competitive inhibitor 93 d1gjja2 not modelled 35.2 19 Fold:LEM/SAP HeH motif Superfamily:LEM domain Family:LEM domain 94 c2iswB_ not modelled 34.8 18 PDB header:lyase Chain: B: PDB Molecule:putative fructose-1,6-bisphosphate aldolase; PDBTitle: structure of giardia fructose-1,6-biphosphate aldolase in2 complex with phosphoglycolohydroxamate 95 c3pm6B_ not modelled 34.8 14 PDB header:lyase Chain: B: PDB Molecule:putative fructose-bisphosphate aldolase; PDBTitle: crystal structure of a putative fructose-1,6-biphosphate aldolase from2 coccidioides immitis solved by combined sad mr 96 c1kdhA_ not modelled 34.8 19 PDB header:transferase/dna Chain: A: PDB Molecule:terminal deoxynucleotidyltransferase short PDBTitle: binary complex of murine terminal deoxynucleotidyl2 transferase with a primer single stranded dna 97 c3k13A_ not modelled 34.5 17 PDB header:transferase Chain: A: PDB Molecule:5-methyltetrahydrofolate-homocysteine methyltransferase; PDBTitle: structure of the pterin-binding domain metr of 5-2 methyltetrahydrofolate-homocysteine methyltransferase from3 bacteroides thetaiotaomicron 98 d1i94m_ not modelled 34.0 20 Fold:S13-like H2TH domain Superfamily:S13-like H2TH domain Family:Ribosomal protein S13 99 c2rrdA_ not modelled 33.9 18 PDB header:dna binding protein Chain: A: PDB Molecule:hrdc domain from bloom syndrome protein; PDBTitle: structure of hrdc domain from human bloom syndrome protein, blm 100 d2gy9m1 not modelled 33.4 15 Fold:S13-like H2TH domain Superfamily:S13-like H2TH domain Family:Ribosomal protein S13 101 c3iz6M_ not modelled 33.4 15 PDB header:ribosome Chain: M: PDB Molecule:40s ribosomal protein s18 (s13p); PDBTitle: localization of the small subunit ribosomal proteins into a 5.5 a2 cryo-em map of triticum aestivum translating 80s ribosome 102 d1dk2a_ not modelled 33.1 7 Fold:SAM domain-like Superfamily:DNA polymerase beta, N-terminal domain-like Family:DNA polymerase beta, N-terminal domain-like 103 c3av0A_ not modelled 32.7 24 PDB header:recombination Chain: A: PDB Molecule:dna double-strand break repair protein mre11; PDBTitle: crystal structure of mre11-rad50 bound to atp s 104 c2xznM_ not modelled 32.4 22 PDB header:ribosome Chain: M: PDB Molecule:rps18e; PDBTitle: crystal structure of the eukaryotic 40s ribosomal2 subunit in complex with initiation factor 1. this file3 contains the 40s subunit and initiation factor for4 molecule 2 105 c1mpgB_ not modelled 32.0 12 PDB header:hydrolase Chain: B: PDB Molecule:3-methyladenine dna glycosylase ii; PDBTitle: 3-methyladenine dna glycosylase ii from escherichia coli 106 c2zkqm_ not modelled 29.7 15 PDB header:ribosomal protein/rna Chain: M: PDB Molecule: PDBTitle: structure of a mammalian ribosomal 40s subunit within an2 80s complex obtained by docking homology models of the rna3 and proteins into an 8.7 a cryo-em map 107 d1rvga_ not modelled 29.4 14 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class II FBP aldolase 108 c2y7eA_ not modelled 29.0 16 PDB header:lyase Chain: A: PDB Molecule:3-keto-5-aminohexanoate cleavage enzyme; PDBTitle: crystal structure of the 3-keto-5-aminohexanoate cleavage enzyme2 (kce) from candidatus cloacamonas acidaminovorans (tetragonal form) 109 c8iczA_ not modelled 28.8 7 PDB header:transferase/dna Chain: A: PDB Molecule:protein (dna polymerase beta (e.c.2.7.7.7)); PDBTitle: dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with2 seven base pairs of dna; soaked in the presence of of datp3 (1 millimolar), mncl2 (5 millimolar), and lithium sulfate4 (75 millimolar) 110 d1jeia_ not modelled 28.6 25 Fold:LEM/SAP HeH motif Superfamily:LEM domain Family:LEM domain 111 d1hl9a2 not modelled 28.3 19 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Putative alpha-L-fucosidase, catalytic domain 112 c3chvA_ not modelled 27.8 18 PDB header:metal binding protein Chain: A: PDB Molecule:prokaryotic domain of unknown function (duf849) with a tim PDBTitle: crystal structure of a prokaryotic domain of unknown function (duf849)2 member (spoa0042) from silicibacter pomeroyi dss-3 at 1.45 a3 resolution 113 d1h5ya_ not modelled 27.4 15 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Histidine biosynthesis enzymes 114 d2uubm1 not modelled 26.7 22 Fold:S13-like H2TH domain Superfamily:S13-like H2TH domain Family:Ribosomal protein S13 115 d1b43a1 not modelled 26.7 26 Fold:SAM domain-like Superfamily:5' to 3' exonuclease, C-terminal subdomain Family:5' to 3' exonuclease, C-terminal subdomain 116 c3majA_ not modelled 26.6 18 PDB header:dna binding protein Chain: A: PDB Molecule:dna processing chain a; PDBTitle: crystal structure of putative dna processing protein dpra from2 rhodopseudomonas palustris cga009 117 c3t18D_ not modelled 26.4 23 PDB header:transferase Chain: D: PDB Molecule:aminotransferase class i and ii; PDBTitle: crystal structure of aminotransferase from anaerococcus prevotii dsm2 20548. 118 d1mc8a1 not modelled 26.4 43 Fold:SAM domain-like Superfamily:5' to 3' exonuclease, C-terminal subdomain Family:5' to 3' exonuclease, C-terminal subdomain 119 c1ut8B_ not modelled 26.4 27 PDB header:hydrolase Chain: B: PDB Molecule:exodeoxyribonuclease; PDBTitle: divalent metal ions (zinc) bound to t5 5'-exonuclease 120 d1ii7a_ not modelled 26.3 13 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:DNA double-strand break repair nuclease

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0