Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	D	L	L	I	I	L	T	Y	V	A	F	A	W	A	M	F	K	I	F	K	I	P	V	N	K	W	T	I	P	T	A	A	L	G	G	I	F	I	V	S	G	L	I	L	L	M	N	Y	N	H	P	Y	T	F	K	A	Q	K	A
Secondary structure
SS confidence
Disorder		?	?	?																	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	I	S	I	P	V	V	P	Q	V	T	G	V	V	I	E	V	T	D	K	K	N	T	L	I	K	K	G	E	V	L	F	R	L	D	P	T	R	Y	Q	A	R	V	D	R	L	M	A	D	I	V	T	A	E	H	K	Q	R	A	L
Secondary structure
SS confidence
Disorder											?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	A	E	L	D	E	M	A	A	N	T	Q	Q	A	K	A	T	R	D	K	F	A	K	E	Y	Q	R	Y	A	R	G	S	Q	A	K	V	N	P	F	S	E	R	D	I	D	V	A	R	Q	N	Y	L	A	Q	E	A	S	V	K	S
Secondary structure
SS confidence
Disorder																																		?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		S	A	A	E	Q	K	Q	I	Q	S	Q	L	D	S	L	V	L	G	E	H	S	Q	I	A	S	L	K	A	Q	L	A	E	A	K	Y	N	L	E	Q	T	I	V	R	A	P	S	D	G	Y	V	T	Q	V	L	I	R	P	G	T	Y
Secondary structure
SS confidence
Disorder													?			?				?	?																																							?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		A	A	S	L	P	L	R	P	V	M	V	F	I	P	D	Q	K	R	Q	I	V	A	Q	F	R	Q	N	S	L	L	R	L	A	P	G	D	D	A	E	V	V	F	N	A	L	P	G	K	V	F	S	G	K	L	A	A	I	S	P	A
Secondary structure
SS confidence
Disorder		?	?																														?	?																											?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		V	P	G	G	A	Y	Q	S	T	G	T	L	Q	T	L	N	T	A	P	G	S	D	G	V	I	A	T	I	E	L	D	E	H	T	D	L	S	A	L	P	D	G	I	Y	A	Q	V	A	V	Y	S	D	H	F	S	H	V	S	V	M
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?			?	?														?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.
Sequence		R	K	V	L	L	R	M	T	S	W	V	H	Y	L	Y	L	D	H
Secondary structure
SS confidence
Disorder																		?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3fpp chain B Region: 48 - 357 Aligned: 260 Modelled: 262 Confidence: 100.0% Identity: 22% PDB header:membrane protein Chain: B: PDB Molecule:macrolide-specific efflux protein maca; PDBTitle: crystal structure of e.coli maca Phyre2 PDB 2f1m chain A Region: 50 - 349 Aligned: 228 Modelled: 236 Confidence: 99.9% Identity: 21% PDB header:transport protein Chain: A: PDB Molecule:acriflavine resistance protein a; PDBTitle: conformational flexibility in the multidrug efflux system protein acra Phyre2 PDB 3lnn chain B Region: 52 - 352 Aligned: 238 Modelled: 242 Confidence: 99.9% Identity: 18% PDB header:metal transport Chain: B: PDB Molecule:membrane fusion protein (mfp) heavy metal cation efflux PDBTitle: crystal structure of zneb from cupriavidus metallidurans Phyre2 PDB 1t5e chain B Region: 56 - 349 Aligned: 214 Modelled: 216 Confidence: 99.9% Identity: 18% PDB header:transport protein Chain: B: PDB Molecule:multidrug resistance protein mexa; PDBTitle: the structure of mexa Phyre2 PDB 1vf7 chain A Region: 50 - 352 Aligned: 223 Modelled: 225 Confidence: 99.9% Identity: 17% Fold: HlyD-like secretion proteins Superfamily: HlyD-like secretion proteins Family: HlyD-like secretion proteins Phyre2 PDB 3h9i chain B Region: 48 - 377 Aligned: 238 Modelled: 240 Confidence: 99.9% Identity: 17% PDB header:transport protein Chain: B: PDB Molecule:cation efflux system protein cusb; PDBTitle: crystal structure of the membrane fusion protein cusb from escherichia2 coli Phyre2 PDB 2k33 chain A Region: 64 - 268 Aligned: 114 Modelled: 115 Confidence: 99.3% Identity: 25% PDB header:membrane protein, transport protein Chain: A: PDB Molecule:acra; PDBTitle: solution structure of an n-glycosylated protein using in2 vitro glycosylation Phyre2 PDB 2b8g chain A Region: 65 - 98 Aligned: 34 Modelled: 34 Confidence: 97.4% Identity: 26% PDB header:biosynthetic protein Chain: A: PDB Molecule:biotin/lipoyl attachment protein; PDBTitle: solution structure of bacillus subtilis blap biotinylated-2 form (energy minimized mean structure) Phyre2 PDB 1dcz chain A Region: 65 - 96 Aligned: 32 Modelled: 32 Confidence: 97.3% Identity: 19% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 2ejg chain D Region: 66 - 96 Aligned: 31 Modelled: 31 Confidence: 97.3% Identity: 23% PDB header:ligase Chain: D: PDB Molecule:149aa long hypothetical methylmalonyl-coa decarboxylase PDBTitle: crystal structure of the biotin protein ligase (mutation r48a) and2 biotin carboxyl carrier protein complex from pyrococcus horikoshii3 ot3 Phyre2 PDB 2l5t chain A Region: 63 - 96 Aligned: 34 Modelled: 34 Confidence: 97.2% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:lipoamide acyltransferase; PDBTitle: solution nmr structure of e2 lipoyl domain from thermoplasma2 acidophilum Phyre2 PDB 1iyu chain A Region: 63 - 98 Aligned: 36 Modelled: 36 Confidence: 97.2% Identity: 31% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 1o78 chain A Region: 66 - 96 Aligned: 31 Modelled: 31 Confidence: 97.1% Identity: 19% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 1bdo chain A Region: 63 - 95 Aligned: 33 Modelled: 33 Confidence: 97.1% Identity: 12% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 2dn8 chain A Region: 66 - 96 Aligned: 31 Modelled: 31 Confidence: 97.1% Identity: 10% PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: solution structure of rsgi ruh-053, an apo-biotin carboxy2 carrier protein from human transcarboxylase Phyre2 PDB 3n6r chain K Region: 63 - 95 Aligned: 33 Modelled: 33 Confidence: 97.1% Identity: 12% PDB header:ligase Chain: K: PDB Molecule:propionyl-coa carboxylase, alpha subunit; PDBTitle: crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc) Phyre2 PDB 2kcc chain A Region: 66 - 96 Aligned: 31 Modelled: 31 Confidence: 97.0% Identity: 10% PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: solution structure of biotinoyl domain from human acetyl-2 coa carboxylase 2 Phyre2 PDB 1ghj chain A Region: 63 - 96 Aligned: 34 Modelled: 34 Confidence: 97.0% Identity: 24% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 1k8m chain A Region: 63 - 98 Aligned: 36 Modelled: 36 Confidence: 97.0% Identity: 14% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 2ejm chain A Region: 63 - 98 Aligned: 36 Modelled: 36 Confidence: 96.9% Identity: 11% PDB header:ligase Chain: A: PDB Molecule:methylcrotonoyl-coa carboxylase subunit alpha; PDBTitle: solution structure of ruh-072, an apo-biotnyl domain form2 human acetyl coenzyme a carboxylase Phyre2 PDB 2rde chain A domain 2 Region: 269 - 376 Aligned: 88 Modelled: 88 Confidence: 56.7% Identity: 14% Fold: Split barrel-like Superfamily: PilZ domain-like Family: PilZ domain-associated domain Phyre2 1 c3fppB_ 2 c2f1mA_ 3 c3lnnB_ 4 c1t5eB_ 5 d1vf7a_ 6 c3h9iB_ 7 c2k33A_ 8 c2b8gA_ 9 d1dcza_ 10 c2ejgD_ 11 c2l5tA_ 12 d1iyua_ 13 d1o78a_ 14 d1bdoa_ 15 c2dn8A_ 16 c3n6rK_ 17 c2kccA_ 18 d1ghja_ 19 d1k8ma_ 20 c2ejmA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 d2rdea2 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3fppB_ 100.0 22 PDB header:membrane protein Chain: B: PDB Molecule:macrolide-specific efflux protein maca; PDBTitle: crystal structure of e.coli maca 2 c2f1mA_ 99.9 21 PDB header:transport protein Chain: A: PDB Molecule:acriflavine resistance protein a; PDBTitle: conformational flexibility in the multidrug efflux system protein acra 3 c3lnnB_ 99.9 18 PDB header:metal transport Chain: B: PDB Molecule:membrane fusion protein (mfp) heavy metal cation efflux PDBTitle: crystal structure of zneb from cupriavidus metallidurans 4 c1t5eB_ 99.9 18 PDB header:transport protein Chain: B: PDB Molecule:multidrug resistance protein mexa; PDBTitle: the structure of mexa 5 d1vf7a_ 99.9 17 Fold:HlyD-like secretion proteins Superfamily:HlyD-like secretion proteins Family:HlyD-like secretion proteins 6 c3h9iB_ 99.9 17 PDB header:transport protein Chain: B: PDB Molecule:cation efflux system protein cusb; PDBTitle: crystal structure of the membrane fusion protein cusb from escherichia2 coli 7 c2k33A_ 99.3 25 PDB header:membrane protein, transport protein Chain: A: PDB Molecule:acra; PDBTitle: solution structure of an n-glycosylated protein using in2 vitro glycosylation 8 c2b8gA_ 97.4 26 PDB header:biosynthetic protein Chain: A: PDB Molecule:biotin/lipoyl attachment protein; PDBTitle: solution structure of bacillus subtilis blap biotinylated-2 form (energy minimized mean structure) 9 d1dcza_ 97.3 19 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 10 c2ejgD_ 97.3 23 PDB header:ligase Chain: D: PDB Molecule:149aa long hypothetical methylmalonyl-coa decarboxylase PDBTitle: crystal structure of the biotin protein ligase (mutation r48a) and2 biotin carboxyl carrier protein complex from pyrococcus horikoshii3 ot3 11 c2l5tA_ 97.2 15 PDB header:transferase Chain: A: PDB Molecule:lipoamide acyltransferase; PDBTitle: solution nmr structure of e2 lipoyl domain from thermoplasma2 acidophilum 12 d1iyua_ 97.2 31 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 13 d1o78a_ 97.1 19 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 14 d1bdoa_ 97.1 12 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 15 c2dn8A_ 97.1 10 PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: solution structure of rsgi ruh-053, an apo-biotin carboxy2 carrier protein from human transcarboxylase 16 c3n6rK_ 97.1 12 PDB header:ligase Chain: K: PDB Molecule:propionyl-coa carboxylase, alpha subunit; PDBTitle: crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc) 17 c2kccA_ 97.0 10 PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: solution structure of biotinoyl domain from human acetyl-2 coa carboxylase 2 18 d1ghja_ 97.0 24 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 19 d1k8ma_ 97.0 14 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 20 c2ejmA_ 96.9 11 PDB header:ligase Chain: A: PDB Molecule:methylcrotonoyl-coa carboxylase subunit alpha; PDBTitle: solution structure of ruh-072, an apo-biotnyl domain form2 human acetyl coenzyme a carboxylase 21 d1qjoa_ not modelled 96.7 21 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 22 d1laba_ not modelled 96.4 26 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 23 d1gjxa_ not modelled 96.4 29 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 24 c2q8iB_ not modelled 96.2 17 PDB header:transferase Chain: B: PDB Molecule:dihydrolipoyllysine-residue acetyltransferase component of PDBTitle: pyruvate dehydrogenase kinase isoform 3 in complex with antitumor drug2 radicicol 25 d1glaf_ not modelled 96.1 29 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like 26 d1pmra_ not modelled 96.1 21 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 27 d2pnrc1 not modelled 96.0 19 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 28 d1y8ob1 not modelled 95.8 17 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 29 c2dncA_ not modelled 95.7 8 PDB header:transferase Chain: A: PDB Molecule:pyruvate dehydrogenase protein x component; PDBTitle: solution structure of rsgi ruh-054, a lipoyl domain from2 human 2-oxoacid dehydrogenase 30 c2qf7A_ not modelled 95.7 19 PDB header:ligase Chain: A: PDB Molecule:pyruvate carboxylase protein; PDBTitle: crystal structure of a complete multifunctional pyruvate carboxylase2 from rhizobium etli 31 c2dneA_ not modelled 95.4 5 PDB header:transferase Chain: A: PDB Molecule:dihydrolipoyllysine-residue acetyltransferase PDBTitle: solution structure of rsgi ruh-058, a lipoyl domain of2 human 2-oxoacid dehydrogenase 32 d2tpta3 not modelled 94.9 12 Fold:alpha/beta-Hammerhead Superfamily:Pyrimidine nucleoside phosphorylase C-terminal domain Family:Pyrimidine nucleoside phosphorylase C-terminal domain 33 d1uoua3 not modelled 94.7 16 Fold:alpha/beta-Hammerhead Superfamily:Pyrimidine nucleoside phosphorylase C-terminal domain Family:Pyrimidine nucleoside phosphorylase C-terminal domain 34 d2gpra_ not modelled 94.6 15 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like 35 c2jkuA_ not modelled 94.6 20 PDB header:ligase Chain: A: PDB Molecule:propionyl-coa carboxylase alpha chain, PDBTitle: crystal structure of the n-terminal region of the biotin2 acceptor domain of human propionyl-coa carboxylase 36 d1brwa3 not modelled 94.4 30 Fold:alpha/beta-Hammerhead Superfamily:Pyrimidine nucleoside phosphorylase C-terminal domain Family:Pyrimidine nucleoside phosphorylase C-terminal domain 37 d2f3ga_ not modelled 94.4 11 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like 38 d1gpra_ not modelled 93.5 11 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like 39 c1otpA_ not modelled 93.2 12 PDB header:phosphorylase Chain: A: PDB Molecule:thymidine phosphorylase; PDBTitle: structural and theoretical studies suggest domain movement produces an2 active conformation of thymidine phosphorylase 40 c2dsjA_ not modelled 93.2 24 PDB header:transferase Chain: A: PDB Molecule:pyrimidine-nucleoside (thymidine) phosphorylase; PDBTitle: crystal structure of project id tt0128 from thermus thermophilus hb8 41 c3h5qA_ not modelled 92.5 27 PDB header:transferase Chain: A: PDB Molecule:pyrimidine-nucleoside phosphorylase; PDBTitle: crystal structure of a putative pyrimidine-nucleoside phosphorylase2 from staphylococcus aureus 42 c2j0fC_ not modelled 92.5 19 PDB header:transferase Chain: C: PDB Molecule:thymidine phosphorylase; PDBTitle: structural basis for non-competitive product inhibition in2 human thymidine phosphorylase: implication for drug design 43 c2hsiB_ not modelled 89.6 17 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative peptidase m23; PDBTitle: crystal structure of putative peptidase m23 from2 pseudomonas aeruginosa, new york structural genomics3 consortium 44 c2gu1A_ not modelled 89.4 23 PDB header:hydrolase Chain: A: PDB Molecule:zinc peptidase; PDBTitle: crystal structure of a zinc containing peptidase from2 vibrio cholerae 45 c3fmcC_ not modelled 89.1 17 PDB header:hydrolase Chain: C: PDB Molecule:putative succinylglutamate desuccinylase / aspartoacylase; PDBTitle: crystal structure of a putative succinylglutamate desuccinylase /2 aspartoacylase family protein (sama_0604) from shewanella amazonensis3 sb2b at 1.80 a resolution 46 c2qj8B_ not modelled 88.9 17 PDB header:hydrolase Chain: B: PDB Molecule:mlr6093 protein; PDBTitle: crystal structure of an aspartoacylase family protein (mlr6093) from2 mesorhizobium loti maff303099 at 2.00 a resolution 47 c2aukA_ not modelled 88.6 20 PDB header:transferase Chain: A: PDB Molecule:dna-directed rna polymerase beta' chain; PDBTitle: structure of e. coli rna polymerase beta' g/g' insert 48 c1brwB_ not modelled 88.2 26 PDB header:transferase Chain: B: PDB Molecule:protein (pyrimidine nucleoside phosphorylase); PDBTitle: the crystal structure of pyrimidine nucleoside2 phosphorylase in a closed conformation 49 d1qwya_ not modelled 86.6 15 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Peptidoglycan hydrolase LytM 50 c3na6A_ not modelled 85.2 9 PDB header:hydrolase Chain: A: PDB Molecule:succinylglutamate desuccinylase/aspartoacylase; PDBTitle: crystal structure of a succinylglutamate desuccinylase (tm1040_2694)2 from silicibacter sp. tm1040 at 2.00 a resolution 51 c2xhaB_ not modelled 84.5 11 PDB header:transcription Chain: B: PDB Molecule:transcription antitermination protein nusg; PDBTitle: crystal structure of domain 2 of thermotoga maritima n-utilization2 substance g (nusg) 52 d1qpoa2 not modelled 84.4 21 Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:NadC N-terminal domain-like 53 c3cdxB_ not modelled 82.6 19 PDB header:hydrolase Chain: B: PDB Molecule:succinylglutamatedesuccinylase/aspartoacylase; PDBTitle: crystal structure of2 succinylglutamatedesuccinylase/aspartoacylase from3 rhodobacter sphaeroides 54 c2b44A_ not modelled 81.3 13 PDB header:hydrolase Chain: A: PDB Molecule:glycyl-glycine endopeptidase lytm; PDBTitle: truncated s. aureus lytm, p 32 2 1 crystal form 55 d1ci3m2 not modelled 80.6 19 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain 56 d1e2wa2 not modelled 80.6 13 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain 57 c2xhcA_ not modelled 79.6 11 PDB header:transcription Chain: A: PDB Molecule:transcription antitermination protein nusg; PDBTitle: crystal structure of thermotoga maritima n-utilization substance g2 (nusg) 58 d1o4ua2 not modelled 78.7 5 Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:NadC N-terminal domain-like 59 c3m9bK_ not modelled 78.7 25 PDB header:chaperone Chain: K: PDB Molecule:proteasome-associated atpase; PDBTitle: crystal structure of the amino terminal coiled coil domain and the2 inter domain of the mycobacterium tuberculosis proteasomal atpase mpa 60 d1qapa2 not modelled 77.7 15 Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:NadC N-terminal domain-like 61 c3it5B_ not modelled 77.2 5 PDB header:hydrolase Chain: B: PDB Molecule:protease lasa; PDBTitle: crystal structure of the lasa virulence factor from pseudomonas2 aeruginosa 62 d1h9ra2 not modelled 74.6 16 Fold:OB-fold Superfamily:MOP-like Family:BiMOP, duplicated molybdate-binding domain 63 c2aujD_ not modelled 72.7 11 PDB header:transferase Chain: D: PDB Molecule:dna-directed rna polymerase beta' chain; PDBTitle: structure of thermus aquaticus rna polymerase beta'-subunit2 insert 64 c3d4rE_ not modelled 71.4 17 PDB header:unknown function Chain: E: PDB Molecule:domain of unknown function from the pfam-b_34464 family; PDBTitle: crystal structure of a duf2118 family protein (mmp0046) from2 methanococcus maripaludis at 2.20 a resolution 65 c3nyyA_ not modelled 70.8 21 PDB header:hydrolase Chain: A: PDB Molecule:putative glycyl-glycine endopeptidase lytm; PDBTitle: crystal structure of a putative glycyl-glycine endopeptidase lytm2 (rumgna_02482) from ruminococcus gnavus atcc 29149 at 1.60 a3 resolution 66 c1o4uA_ not modelled 66.7 10 PDB header:transferase Chain: A: PDB Molecule:type ii quinolic acid phosphoribosyltransferase; PDBTitle: crystal structure of a nicotinate nucleotide pyrophosphorylase2 (tm1645) from thermotoga maritima at 2.50 a resolution 67 c3gnnA_ not modelled 65.5 5 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of nicotinate-nucleotide2 pyrophosphorylase from burkholderi pseudomallei 68 c1e2vB_ not modelled 64.3 13 PDB header:electron transport proteins Chain: B: PDB Molecule:cytochrome f; PDBTitle: n153q mutant of cytochrome f from chlamydomonas reinhardtii 69 c1ctmA_ not modelled 64.0 25 PDB header:electron transport(cytochrome) Chain: A: PDB Molecule:cytochrome f; PDBTitle: crystal structure of chloroplast cytochrome f reveals a2 novel cytochrome fold and unexpected heme ligation 70 c3pajA_ not modelled 63.1 15 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase, carboxylating; PDBTitle: 2.00 angstrom resolution crystal structure of a quinolinate2 phosphoribosyltransferase from vibrio cholerae o1 biovar eltor str.3 n16961 71 d1fr3a_ not modelled 62.5 19 Fold:OB-fold Superfamily:MOP-like Family:Molybdate/tungstate binding protein MOP 72 c2jbmA_ not modelled 62.4 0 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: qprtase structure from human 73 c2jxmB_ not modelled 62.1 19 PDB header:electron transport Chain: B: PDB Molecule:cytochrome f; PDBTitle: ensemble of twenty structures of the prochlorothrix2 hollandica plastocyanin- cytochrome f complex 74 c1qapA_ not modelled 62.1 11 PDB header:glycosyltransferase Chain: A: PDB Molecule:quinolinic acid phosphoribosyltransferase; PDBTitle: quinolinic acid phosphoribosyltransferase with bound2 quinolinic acid 75 c3tqvA_ not modelled 61.3 9 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: structure of the nicotinate-nucleotide pyrophosphorylase from2 francisella tularensis. 76 c3l0gD_ not modelled 61.2 20 PDB header:transferase Chain: D: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of nicotinate-nucleotide pyrophosphorylase from2 ehrlichia chaffeensis at 2.05a resolution 77 c3csqC_ not modelled 61.1 20 PDB header:hydrolase Chain: C: PDB Molecule:morphogenesis protein 1; PDBTitle: crystal and cryoem structural studies of a cell wall2 degrading enzyme in the bacteriophage phi29 tail 78 d2ix0a1 not modelled 60.3 11 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 79 c1q90A_ not modelled 59.7 13 PDB header:photosynthesis Chain: A: PDB Molecule:apocytochrome f; PDBTitle: structure of the cytochrome b6f (plastohydroquinone : plastocyanin2 oxidoreductase) from chlamydomonas reinhardtii 80 c1tu2B_ not modelled 59.2 19 PDB header:electron transport Chain: B: PDB Molecule:apocytochrome f; PDBTitle: the complex of nostoc cytochrome f and plastocyanin determin with2 paramagnetic nmr. based on the structures of cytochrome f and3 plastocyanin, 10 structures 81 d2rdea2 56.7 14 Fold:Split barrel-like Superfamily:PilZ domain-like Family:PilZ domain-associated domain 82 c2e75C_ not modelled 56.4 31 PDB header:photosynthesis Chain: C: PDB Molecule:apocytochrome f; PDBTitle: crystal structure of the cytochrome b6f complex with 2-nonyl-4-2 hydroxyquinoline n-oxide (nqno) from m.laminosus 83 d1tu2b2 not modelled 56.0 19 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain 84 c2b7pA_ not modelled 55.0 13 PDB header:transferase Chain: A: PDB Molecule:probable nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of quinolinic acid phosphoribosyltransferase from2 helicobacter pylori 85 c3ghgK_ not modelled 54.5 8 PDB header:blood clotting Chain: K: PDB Molecule:fibrinogen beta chain; PDBTitle: crystal structure of human fibrinogen 86 d1onla_ not modelled 53.3 24 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 87 c3iftA_ not modelled 53.1 24 PDB header:oxidoreductase Chain: A: PDB Molecule:glycine cleavage system h protein; PDBTitle: crystal structure of glycine cleavage system protein h from2 mycobacterium tuberculosis, using x-rays from the compact light3 source. 88 d1krha1 not modelled 53.0 20 Fold:Reductase/isomerase/elongation factor common domain Superfamily:Riboflavin synthase domain-like Family:Ferredoxin reductase FAD-binding domain-like 89 c2edgA_ not modelled 52.3 28 PDB header:biosynthetic protein Chain: A: PDB Molecule:glycine cleavage system h protein; PDBTitle: solution structure of the gcv_h domain from mouse glycine 90 c1qpoA_ not modelled 48.7 14 PDB header:transferase Chain: A: PDB Molecule:quinolinate acid phosphoribosyl transferase; PDBTitle: quinolinate phosphoribosyl transferase (qaprtase) apo-enzyme from2 mycobacterium tuberculosis 91 c3mxuA_ not modelled 45.4 16 PDB header:oxidoreductase Chain: A: PDB Molecule:glycine cleavage system h protein; PDBTitle: crystal structure of glycine cleavage system protein h from bartonella2 henselae 92 c1x1oC_ not modelled 45.1 7 PDB header:transferase Chain: C: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of project id tt0268 from thermus thermophilus hb8 93 c1h9sA_ not modelled 44.7 18 PDB header:transcription regulator Chain: A: PDB Molecule:molybdenum transport protein mode; PDBTitle: molybdate bound complex of dimop domain of mode from e.coli 94 d1h9ra1 not modelled 44.6 15 Fold:OB-fold Superfamily:MOP-like Family:BiMOP, duplicated molybdate-binding domain 95 c1h9mB_ not modelled 43.5 17 PDB header:binding protein Chain: B: PDB Molecule:molybdenum-binding-protein; PDBTitle: two crystal structures of the cytoplasmic molybdate-binding2 protein modg suggest a novel cooperative binding mechanism3 and provide insights into ligand-binding specificity.4 peg-grown form with molybdate bound 96 d1hpca_ not modelled 42.1 20 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 97 d1hcza2 not modelled 39.6 25 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain 98 c3kygB_ not modelled 37.3 10 PDB header:unknown function Chain: B: PDB Molecule:putative uncharacterized protein vca0042; PDBTitle: crystal structure of vca0042 (l135r) complexed with c-di-gmp 99 d1vf5c2 not modelled 36.3 31 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain 100 c3a8jF_ not modelled 36.0 12 PDB header:transferase/transport protein Chain: F: PDB Molecule:glycine cleavage system h protein; PDBTitle: crystal structure of et-ehred complex 101 c2jz2A_ not modelled 35.7 22 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:ssl0352 protein; PDBTitle: solution nmr structure of ssl0352 protein from synechocystis sp. pcc2 6803. northeast structural genomics consortium target sgr42 102 c2rdeB_ not modelled 35.0 9 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein vca0042; PDBTitle: crystal structure of vca0042 complexed with c-di-gmp 103 c1y4cA_ not modelled 33.8 9 PDB header:de novo protein Chain: A: PDB Molecule:maltose binding protein fused with designed PDBTitle: designed helical protein fusion mbp 104 d1nppa2 not modelled 33.8 21 Fold:SH3-like barrel Superfamily:Translation proteins SH3-like domain Family:N-utilization substance G protein NusG, C-terminal domain 105 c1ei3E_ not modelled 33.7 6 PDB header: PDB COMPND: 106 d1nz9a_ not modelled 33.6 26 Fold:SH3-like barrel Superfamily:Translation proteins SH3-like domain Family:N-utilization substance G protein NusG, C-terminal domain 107 c3ojaB_ not modelled 33.5 15 PDB header:protein binding Chain: B: PDB Molecule:anopheles plasmodium-responsive leucine-rich repeat protein PDBTitle: crystal structure of lrim1/apl1c complex 108 c1deqO_ not modelled 33.5 4 PDB header: PDB COMPND: 109 c3tbiB_ not modelled 32.9 14 PDB header:transcription Chain: B: PDB Molecule:dna-directed rna polymerase subunit beta; PDBTitle: crystal structure of t4 gp33 bound to e. coli rnap beta-flap domain 110 c2jvvA_ not modelled 32.8 16 PDB header:transcription Chain: A: PDB Molecule:transcription antitermination protein nusg; PDBTitle: solution structure of e. coli nusg carboxyterminal domain 111 c2kvqG_ not modelled 32.8 16 PDB header:transcription Chain: G: PDB Molecule:transcription antitermination protein nusg; PDBTitle: solution structure of nuse:nusg-ctd complex 112 c3d37A_ not modelled 32.2 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:tail protein, 43 kda; PDBTitle: the crystal structure of the tail protein from neisseria meningitidis2 mc58 113 c3n4xB_ not modelled 31.2 12 PDB header:replication Chain: B: PDB Molecule:monopolin complex subunit csm1; PDBTitle: structure of csm1 full-length 114 c2bkdN_ not modelled 30.6 6 PDB header:nuclear protein Chain: N: PDB Molecule:fragile x mental retardation 1 protein; PDBTitle: structure of the n-terminal domain of fragile x mental2 retardation protein 115 d2je6i2 not modelled 30.3 22 Fold:Barrel-sandwich hybrid Superfamily:Ribosomal L27 protein-like Family:ECR1 N-terminal domain-like 116 d2c78a2 not modelled 28.8 9 Fold:Elongation factor/aminomethyltransferase common domain Superfamily:EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain Family:EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 117 d1whla_ not modelled 26.7 25 Fold:SH3-like barrel Superfamily:Cap-Gly domain Family:Cap-Gly domain 118 d1efca2 not modelled 26.0 19 Fold:Elongation factor/aminomethyltransferase common domain Superfamily:EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain Family:EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 119 d1psea_ not modelled 25.5 13 Fold:SH3-like barrel Superfamily:Electron transport accessory proteins Family:Photosystem I accessory protein E (PsaE) 120 d1jb0e_ not modelled 24.4 15 Fold:SH3-like barrel Superfamily:Electron transport accessory proteins Family:Photosystem I accessory protein E (PsaE)

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0