Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	E	I	Y	E	N	E	N	D	Q	V	E	A	V	K	R	F	F	A	E	N	G	K	A	L	A	V	G	V	I	L	G	V	G	A	L	I	G	W	R	Y	W	N	S	H	Q	V	D	S	A	R	S	A	S	L	A	Y	Q	N	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	T	A	V	S	E	G	K	P	D	S	I	P	A	A	E	K	F	A	A	E	N	K	N	T	Y	G	A	L	A	S	L	E	L	A	Q	Q	F	V	D	K	N	E	L	E	K	A	A	A	Q	L	Q	Q	G	L	A	D	T	S	D
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?	?										?	?		?																			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		E	N	L	K	A	V	I	N	L	R	L	A	R	V	Q	V	Q	L	K	Q	A	D	A	A	L	K	T	L	D	T	I	K	G	E	G	W	A	A	I	V	A	D	L	R	G	E	A	L	L	S	K	G	D	K	Q	G	A	R	S	A
Secondary structure
SS confidence
Disorder																																?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.
Sequence		W	E	A	G	V	K	S	D	V	T	P	A	L	S	E	M	M	Q	M	K	I	N	N	L	S	I
Secondary structure
SS confidence
Disorder								?	?	?	?		?	?	?									?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2xev chain B Region: 90 - 204 Aligned: 115 Modelled: 115 Confidence: 99.6% Identity: 10% PDB header:metal binding Chain: B: PDB Molecule:ybgf; PDBTitle: crystal structure of the tpr domain of xanthomonas2 campestris ybgf Phyre2 PDB 2e2e chain A Region: 64 - 202 Aligned: 137 Modelled: 139 Confidence: 99.5% Identity: 9% PDB header:lyase Chain: A: PDB Molecule:formate-dependent nitrite reductase complex nrfg subunit; PDBTitle: tpr domain of nrfg mediates the complex formation between heme lyase2 and formate-dependent nitrite reductase in escherichia coli o157:h7 Phyre2 PDB 1wao chain 4 Region: 88 - 204 Aligned: 114 Modelled: 117 Confidence: 99.5% Identity: 15% PDB header:hydrolase Chain: 4: PDB Molecule:serine/threonine protein phosphatase 5; PDBTitle: pp5 structure Phyre2 PDB 3pe3 chain D Region: 51 - 201 Aligned: 146 Modelled: 151 Confidence: 99.4% Identity: 12% PDB header:transferase Chain: D: PDB Molecule:udp-n-acetylglucosamine--peptide n- PDBTitle: structure of human o-glcnac transferase and its complex with a peptide2 substrate Phyre2 PDB 2xpi chain A Region: 34 - 200 Aligned: 167 Modelled: 167 Confidence: 99.4% Identity: 16% PDB header:cell cycle Chain: A: PDB Molecule:anaphase-promoting complex subunit cut9; PDBTitle: crystal structure of apc/c hetero-tetramer cut9-hcn1 Phyre2 PDB 3gyz chain B Region: 84 - 204 Aligned: 118 Modelled: 121 Confidence: 99.4% Identity: 14% PDB header:chaperone Chain: B: PDB Molecule:chaperone protein ipgc; PDBTitle: crystal structure of ipgc from shigella flexneri Phyre2 PDB 2xcb chain A Region: 84 - 204 Aligned: 118 Modelled: 121 Confidence: 99.4% Identity: 14% PDB header:protein binding Chain: A: PDB Molecule:regulatory protein pcrh; PDBTitle: crystal structure of pcrh in complex with the chaperone2 binding region of popd Phyre2 PDB 1elw chain A Region: 88 - 203 Aligned: 113 Modelled: 116 Confidence: 99.4% Identity: 9% Fold: alpha-alpha superhelix Superfamily: TPR-like Family: Tetratricopeptide repeat (TPR) Phyre2 PDB 2dba chain A Region: 88 - 203 Aligned: 116 Modelled: 116 Confidence: 99.4% Identity: 16% PDB header:structural protein Chain: A: PDB Molecule:smooth muscle cell associated protein-1, isoform PDBTitle: the solution structure of the tetratrico peptide repeat of2 human smooth muscle cell associated protein-1, isoform 2 Phyre2 PDB 2c2l chain A domain 1 Region: 88 - 192 Aligned: 102 Modelled: 105 Confidence: 99.3% Identity: 16% Fold: alpha-alpha superhelix Superfamily: TPR-like Family: Tetratricopeptide repeat (TPR) Phyre2 PDB 2bug chain A domain 1 Region: 88 - 204 Aligned: 114 Modelled: 117 Confidence: 99.3% Identity: 15% Fold: alpha-alpha superhelix Superfamily: TPR-like Family: Tetratricopeptide repeat (TPR) Phyre2 PDB 2gw1 chain A Region: 88 - 201 Aligned: 110 Modelled: 114 Confidence: 99.3% Identity: 15% PDB header:protein transport Chain: A: PDB Molecule:mitochondrial precursor proteins import receptor; PDBTitle: crystal structure of the yeast tom70 Phyre2 PDB 1nzn chain A Region: 93 - 202 Aligned: 110 Modelled: 110 Confidence: 99.3% Identity: 9% Fold: alpha-alpha superhelix Superfamily: TPR-like Family: Tetratricopeptide repeat (TPR) Phyre2 PDB 2vyi chain A Region: 83 - 201 Aligned: 116 Modelled: 119 Confidence: 99.3% Identity: 13% PDB header:chaperone Chain: A: PDB Molecule:sgta protein; PDBTitle: crystal structure of the tpr domain of human sgt Phyre2 PDB 2y4t chain A Region: 88 - 201 Aligned: 111 Modelled: 114 Confidence: 99.3% Identity: 22% PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily c member 3; PDBTitle: crystal structure of the human co-chaperone p58(ipk) Phyre2 PDB 3sz7 chain A Region: 82 - 199 Aligned: 114 Modelled: 118 Confidence: 99.3% Identity: 15% PDB header:chaperone regulator Chain: A: PDB Molecule:hsc70 cochaperone (sgt); PDBTitle: crystal structure of the sgt2 tpr domain from aspergillus fumigatus Phyre2 PDB 2c2l chain D Region: 88 - 192 Aligned: 102 Modelled: 105 Confidence: 99.3% Identity: 16% PDB header:chaperone Chain: D: PDB Molecule:carboxy terminus of hsp70-interacting protein; PDBTitle: crystal structure of the chip u-box e3 ubiquitin ligase Phyre2 PDB 3mv3 chain B Region: 59 - 205 Aligned: 147 Modelled: 147 Confidence: 99.3% Identity: 7% PDB header:protein transport Chain: B: PDB Molecule:coatomer subunit epsilon; PDBTitle: crystal structure of a-cop in complex with e-cop Phyre2 PDB 3rkv chain A Region: 87 - 201 Aligned: 115 Modelled: 115 Confidence: 99.2% Identity: 12% PDB header:isomerase Chain: A: PDB Molecule:putative peptidylprolyl isomerase; PDBTitle: c-terminal domain of protein c56c10.10, a putative peptidylprolyl2 isomerase, from caenorhabditis elegans Phyre2 PDB 1a17 chain A Region: 87 - 204 Aligned: 115 Modelled: 118 Confidence: 99.2% Identity: 15% Fold: alpha-alpha superhelix Superfamily: TPR-like Family: Tetratricopeptide repeat (TPR) Phyre2 PDB 3hd7 chain A Region: 15 - 42 Aligned: 28 Modelled: 28 Confidence: 73.3% Identity: 21% PDB header:exocytosis Chain: A: PDB Molecule:vesicle-associated membrane protein 2; PDBTitle: helical extension of the neuronal snare complex into the membrane,2 spacegroup c 1 2 1 Phyre2 1 c2xevB_ 2 c2e2eA_ 3 c1wao4_ 4 c3pe3D_ 5 c2xpiA_ 6 c3gyzB_ 7 c2xcbA_ 8 d1elwa_ 9 c2dbaA_ 10 d2c2la1 11 d2buga1 12 c2gw1A_ 13 d1nzna_ 14 c2vyiA_ 15 c2y4tA_ 16 c3sz7A_ 17 c2c2lD_ 18 c3mv3B_ 19 c3rkvA_ 20 d1a17a_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 c3hd7A_ 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2xevB_ 99.6 10 PDB header:metal binding Chain: B: PDB Molecule:ybgf; PDBTitle: crystal structure of the tpr domain of xanthomonas2 campestris ybgf 2 c2e2eA_ 99.5 9 PDB header:lyase Chain: A: PDB Molecule:formate-dependent nitrite reductase complex nrfg subunit; PDBTitle: tpr domain of nrfg mediates the complex formation between heme lyase2 and formate-dependent nitrite reductase in escherichia coli o157:h7 3 c1wao4_ 99.5 15 PDB header:hydrolase Chain: 4: PDB Molecule:serine/threonine protein phosphatase 5; PDBTitle: pp5 structure 4 c3pe3D_ 99.4 12 PDB header:transferase Chain: D: PDB Molecule:udp-n-acetylglucosamine--peptide n- PDBTitle: structure of human o-glcnac transferase and its complex with a peptide2 substrate 5 c2xpiA_ 99.4 16 PDB header:cell cycle Chain: A: PDB Molecule:anaphase-promoting complex subunit cut9; PDBTitle: crystal structure of apc/c hetero-tetramer cut9-hcn1 6 c3gyzB_ 99.4 14 PDB header:chaperone Chain: B: PDB Molecule:chaperone protein ipgc; PDBTitle: crystal structure of ipgc from shigella flexneri 7 c2xcbA_ 99.4 14 PDB header:protein binding Chain: A: PDB Molecule:regulatory protein pcrh; PDBTitle: crystal structure of pcrh in complex with the chaperone2 binding region of popd 8 d1elwa_ 99.4 9 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 9 c2dbaA_ 99.4 16 PDB header:structural protein Chain: A: PDB Molecule:smooth muscle cell associated protein-1, isoform PDBTitle: the solution structure of the tetratrico peptide repeat of2 human smooth muscle cell associated protein-1, isoform 2 10 d2c2la1 99.3 16 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 11 d2buga1 99.3 15 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 12 c2gw1A_ 99.3 15 PDB header:protein transport Chain: A: PDB Molecule:mitochondrial precursor proteins import receptor; PDBTitle: crystal structure of the yeast tom70 13 d1nzna_ 99.3 9 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 14 c2vyiA_ 99.3 13 PDB header:chaperone Chain: A: PDB Molecule:sgta protein; PDBTitle: crystal structure of the tpr domain of human sgt 15 c2y4tA_ 99.3 22 PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily c member 3; PDBTitle: crystal structure of the human co-chaperone p58(ipk) 16 c3sz7A_ 99.3 15 PDB header:chaperone regulator Chain: A: PDB Molecule:hsc70 cochaperone (sgt); PDBTitle: crystal structure of the sgt2 tpr domain from aspergillus fumigatus 17 c2c2lD_ 99.3 16 PDB header:chaperone Chain: D: PDB Molecule:carboxy terminus of hsp70-interacting protein; PDBTitle: crystal structure of the chip u-box e3 ubiquitin ligase 18 c3mv3B_ 99.3 7 PDB header:protein transport Chain: B: PDB Molecule:coatomer subunit epsilon; PDBTitle: crystal structure of a-cop in complex with e-cop 19 c3rkvA_ 99.2 12 PDB header:isomerase Chain: A: PDB Molecule:putative peptidylprolyl isomerase; PDBTitle: c-terminal domain of protein c56c10.10, a putative peptidylprolyl2 isomerase, from caenorhabditis elegans 20 d1a17a_ 99.2 15 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 21 d1iyga_ not modelled 99.2 7 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 22 c3q49B_ not modelled 99.2 16 PDB header:ligase/chaperone Chain: B: PDB Molecule:stip1 homology and u box-containing protein 1; PDBTitle: crystal structure of the tpr domain of chip complexed with hsp70-c2 peptide 23 d1pc2a_ not modelled 99.2 9 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 24 c2kckA_ not modelled 99.2 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:tpr repeat; PDBTitle: nmr solution structure of the northeast structural genomics2 consortium (nesg) target mrr121a 25 d1w3ba_ not modelled 99.2 17 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 26 c1kt0A_ not modelled 99.2 18 PDB header:isomerase Chain: A: PDB Molecule:51 kda fk506-binding protein; PDBTitle: structure of the large fkbp-like protein, fkbp51, involved in steroid2 receptor complexes 27 d1elra_ not modelled 99.2 15 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 28 d1p5qa1 not modelled 99.2 15 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 29 c1ihgA_ not modelled 99.2 8 PDB header:isomerase Chain: A: PDB Molecule:cyclophilin 40; PDBTitle: bovine cyclophilin 40, monoclinic form 30 c2r5sB_ not modelled 99.2 12 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein vp0806; PDBTitle: the crystal structure of a domain of protein vp0806 (unknown function)2 from vibrio parahaemolyticus rimd 2210633 31 c2ho1B_ not modelled 99.2 12 PDB header:protein binding Chain: B: PDB Molecule:type 4 fimbrial biogenesis protein pilf; PDBTitle: functional characterization of pseudomonas aeruginosa pilf 32 d2hr2a1 not modelled 99.2 21 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:CT2138-like 33 c3urzB_ not modelled 99.2 12 PDB header:protein binding Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a hypothetical protein (bacova_03105) from2 bacteroides ovatus atcc 8483 at 2.19 a resolution 34 c2fbnA_ not modelled 99.2 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:70 kda peptidylprolyl isomerase, putative; PDBTitle: plasmodium falciparum putative fk506-binding protein2 pfl2275c, c-terminal tpr-containing domain 35 d2fbna1 not modelled 99.2 17 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 36 c1qz2B_ not modelled 99.1 15 PDB header:isomerase/chaperone Chain: B: PDB Molecule:fk506-binding protein 4; PDBTitle: crystal structure of fkbp52 c-terminal domain complex with2 the c-terminal peptide meevd of hsp90 37 c3iegB_ not modelled 99.1 20 PDB header:chaperone Chain: B: PDB Molecule:dnaj homolog subfamily c member 3; PDBTitle: crystal structure of p58(ipk) tpr domain at 2.5 a 38 c2hyzA_ not modelled 99.1 16 PDB header:de novo protein Chain: A: PDB Molecule:synthetic consensus tpr protein; PDBTitle: crystal structure of an 8 repeat consensus tpr superhelix2 (orthorombic crystal form) 39 d1kt1a1 not modelled 99.1 16 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 40 c2q7fA_ not modelled 99.1 15 PDB header:protein binding Chain: A: PDB Molecule:yrrb protein; PDBTitle: crystal structure of yrrb: a tpr protein with an unusual peptide-2 binding site 41 c3gw4B_ not modelled 99.1 11 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of uncharacterized protein from deinococcus2 radiodurans. northeast structural genomics consortium target drr162b. 42 d1hh8a_ not modelled 99.1 14 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 43 c2vq2A_ not modelled 99.1 13 PDB header:structural protein Chain: A: PDB Molecule:putative fimbrial biogenesis and twitching PDBTitle: crystal structure of pilw, widely conserved type iv pilus2 biogenesis factor 44 d1ihga1 not modelled 99.1 9 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 45 d1d8da_ not modelled 99.1 10 Fold:alpha-alpha superhelix Superfamily:Protein prenylyltransferase Family:Protein prenylyltransferase 46 d1xnfa_ not modelled 99.1 18 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 47 d2h6fa1 not modelled 99.1 10 Fold:alpha-alpha superhelix Superfamily:Protein prenylyltransferase Family:Protein prenylyltransferase 48 d1hxia_ not modelled 99.1 12 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 49 c2pl2A_ not modelled 99.1 16 PDB header:protein binding Chain: A: PDB Molecule:hypothetical conserved protein ttc0263; PDBTitle: crystal structure of ttc0263: a thermophilic tpr protein in thermus2 thermophilus hb27 50 c3fp4A_ not modelled 99.1 12 PDB header:transport protein Chain: A: PDB Molecule:tpr repeat-containing protein yhr117w; PDBTitle: crystal structure of tom71 complexed with ssa1 c-terminal2 fragment 51 c3k9iA_ not modelled 99.1 12 PDB header:protein binding Chain: A: PDB Molecule:bh0479 protein; PDBTitle: crystal structure of putative protein binding protein (np_241345.1)2 from bacillus halodurans at 2.71 a resolution 52 c3as5A_ not modelled 99.0 10 PDB header:protein binding Chain: A: PDB Molecule:mama; PDBTitle: mama amb-1 p212121 53 c3cvpA_ not modelled 99.0 17 PDB header:transport protein Chain: A: PDB Molecule:peroxisome targeting signal 1 receptor pex5; PDBTitle: structure of peroxisomal targeting signal 1 (pts1) binding2 domain of trypanosoma brucei peroxin 5 (tbpex5)complexed3 to pts1 peptide (10-skl) 54 c3ly8A_ not modelled 99.0 16 PDB header:signaling protein Chain: A: PDB Molecule:transcriptional activator cadc; PDBTitle: crystal structure of mutant d471e of the periplasmic domain of cadc 55 c1tnoI_ not modelled 99.0 10 PDB header:transferase Chain: I: PDB Molecule:geranylgeranyltransferase type i alpha subunit; PDBTitle: rat protein geranylgeranyltransferase type-i complexed with2 a ggpp analog and a kkksktkcvim peptide derived from k-3 ras4b 56 c3hymB_ not modelled 99.0 17 PDB header:cell cycle, ligase Chain: B: PDB Molecule:cell division cycle protein 16 homolog; PDBTitle: insights into anaphase promoting complex tpr subdomain2 assembly from a cdc26-apc6 structure 57 c3q75A_ not modelled 99.0 10 PDB header:transferase Chain: A: PDB Molecule:farnesyltransferase alpha subunit; PDBTitle: cryptococcus neoformans protein farnesyltransferase in complex with2 fpt-ii and tkcvvm peptide 58 d1tjca_ not modelled 99.0 13 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 59 c3qdnA_ not modelled 99.0 17 PDB header:oxidoreductase Chain: A: PDB Molecule:putative thioredoxin protein; PDBTitle: putative thioredoxin protein from salmonella typhimurium 60 c3mkrA_ not modelled 99.0 9 PDB header:transport protein Chain: A: PDB Molecule:coatomer subunit epsilon; PDBTitle: crystal structure of yeast alpha/epsilon-cop subcomplex of the copi2 vesicular coat 61 c2kc7A_ not modelled 98.9 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:bfr218_protein; PDBTitle: solution nmr structure of bacteroides fragilis protein2 bf1650. northeast structural genomics consortium target3 bfr218 62 d1zu2a1 not modelled 98.9 10 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 63 c2yhcA_ not modelled 98.9 17 PDB header:membrane protein Chain: A: PDB Molecule:upf0169 lipoprotein yfio; PDBTitle: structure of bamd from e. coli 64 c1fchB_ not modelled 98.9 10 PDB header:signaling protein Chain: B: PDB Molecule:peroxisomal targeting signal 1 receptor; PDBTitle: crystal structure of the pts1 complexed to the tpr region2 of human pex5 65 c2if4A_ not modelled 98.9 23 PDB header:signaling protein Chain: A: PDB Molecule:atfkbp42; PDBTitle: crystal structure of a multi-domain immunophilin from2 arabidopsis thaliana 66 c2katA_ not modelled 98.9 26 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution structure of protein bpp2914 from bordetella2 parapertussis. northeast structural genomics consortium3 target bpr206 67 c3qkyA_ not modelled 98.8 19 PDB header:membrane protein Chain: A: PDB Molecule:outer membrane assembly lipoprotein yfio; PDBTitle: crystal structure of rhodothermus marinus bamd 68 c2ifuA_ not modelled 98.8 18 PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:gamma-snap; PDBTitle: crystal structure of a gamma-snap from danio rerio 69 c2avpA_ not modelled 98.8 19 PDB header:de novo protein Chain: A: PDB Molecule:synthetic consensus tpr protein; PDBTitle: crystal structure of an 8 repeat consensus tpr superhelix 70 c2vsnB_ not modelled 98.8 17 PDB header:transferase Chain: B: PDB Molecule:xcogt; PDBTitle: structure and topological arrangement of an o-glcnac2 transferase homolog: insight into molecular control of3 intracellular glycosylation 71 c3sf4B_ not modelled 98.8 16 PDB header:signaling protein/protein binding Chain: B: PDB Molecule:g-protein-signaling modulator 2; PDBTitle: crystal structure of the complex between the conserved cell polarity2 proteins inscuteable and lgn 72 d1hz4a_ not modelled 98.8 13 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Transcription factor MalT domain III 73 d2ooea1 not modelled 98.8 13 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:HAT/Suf repeat 74 d1zbpa1 not modelled 98.7 9 Fold:ImpE-like Superfamily:ImpE-like Family:ImpE-like 75 c3n71A_ not modelled 98.7 7 PDB header:transcription Chain: A: PDB Molecule:histone lysine methyltransferase smyd1; PDBTitle: crystal structure of cardiac specific histone methyltransferase smyd1 76 d1dcea1 not modelled 98.7 9 Fold:alpha-alpha superhelix Superfamily:Protein prenylyltransferase Family:Protein prenylyltransferase 77 d1fcha_ not modelled 98.7 10 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 78 c3fflC_ not modelled 98.7 10 PDB header:cell cycle Chain: C: PDB Molecule:anaphase-promoting complex subunit 7; PDBTitle: crystal structure of the n-terminal domain of anaphase-2 promoting complex subunit 7 79 c2vgxA_ not modelled 98.7 16 PDB header:chaperone Chain: A: PDB Molecule:chaperone sycd; PDBTitle: structure of the yersinia enterocolitica type iii secretion2 translocator chaperone sycd 80 c3q15A_ not modelled 98.7 10 PDB header:hydrolase/kinase Chain: A: PDB Molecule:response regulator aspartate phosphatase h; PDBTitle: crystal structure of raph complexed with spo0f 81 c2kcvA_ not modelled 98.7 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:tetratricopeptide repeat domain protein; PDBTitle: solution nmr structure of tetratricopeptide repeat domain2 protein sru_0103 from salinibacter ruber, northeast3 structural genomics consortium (nesg) target srr115c 82 c3ulqA_ not modelled 98.7 12 PDB header:gene regulation/transcription activator Chain: A: PDB Molecule:response regulator aspartate phosphatase f; PDBTitle: crystal structure of the anti-activator rapf complexed with the2 response regulator coma dna binding domain 83 d1y8ma1 not modelled 98.6 10 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 84 d1qsaa1 not modelled 98.6 8 Fold:alpha-alpha superhelix Superfamily:Bacterial muramidases Family:Bacterial muramidases 85 c2l6jA_ not modelled 98.6 13 PDB header:protein binding Chain: A: PDB Molecule:tpr repeat-containing protein associated with hsp90; PDBTitle: tah1 complexed by meevd 86 c3draA_ not modelled 98.6 8 PDB header:transferase Chain: A: PDB Molecule:protein PDBTitle: candida albicans protein geranylgeranyltransferase-i2 complexed with ggpp 87 c1na3A_ not modelled 98.5 18 PDB header:de novo protein Chain: A: PDB Molecule:designed protein ctpr2; PDBTitle: design of stable alpha-helical arrays from an idealized tpr2 motif 88 d1qqea_ not modelled 98.5 11 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 89 c3beeB_ not modelled 98.5 12 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative yfre protein; PDBTitle: crystal structure of putative yfre protein from vibrio2 parahaemolyticus 90 d2pqrb1 not modelled 98.4 10 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 91 c3mekA_ not modelled 98.3 13 PDB header:transferase Chain: A: PDB Molecule:set and mynd domain-containing protein 3; PDBTitle: crystal structure of human histone-lysine n-2 methyltransferase smyd3 in complex with s-adenosyl-l-3 methionine 92 d2ff4a2 not modelled 98.3 15 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:BTAD-like 93 c3qwvA_ not modelled 98.3 11 PDB header:transferase Chain: A: PDB Molecule:set and mynd domain-containing protein 2; PDBTitle: crystal structure of histone lysine methyltransferase smyd2 in complex2 with the cofactor product adohcy 94 c3oxgA_ not modelled 98.3 13 PDB header:transferase Chain: A: PDB Molecule:set and mynd domain-containing protein 3; PDBTitle: human lysine methyltransferase smyd3 in complex with adohcy (form iii) 95 c2qfcB_ not modelled 98.1 14 PDB header:transcription regulation Chain: B: PDB Molecule:plcr protein; PDBTitle: crystal structure of bacillus thuringiensis plcr complexed with papr 96 c3ceqB_ not modelled 98.0 9 PDB header:motor protein, transport protein Chain: B: PDB Molecule:kinesin light chain 2; PDBTitle: the tpr domain of human kinesin light chain 2 (hklc2) 97 d2onda1 not modelled 97.9 15 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:HAT/Suf repeat 98 c1slyA_ not modelled 97.8 11 PDB header:glycosyltransferase Chain: A: PDB Molecule:70-kda soluble lytic transglycosylase; PDBTitle: complex of the 70-kda soluble lytic transglycosylase with2 bulgecin a 99 c2uy1A_ not modelled 97.7 11 PDB header:rna-binding protein Chain: A: PDB Molecule:cleavage stimulation factor 77; PDBTitle: crystal structure of cstf-77 100 c1xi4D_ not modelled 97.7 9 PDB header:endocytosis/exocytosis Chain: D: PDB Molecule:clathrin heavy chain; PDBTitle: clathrin d6 coat 101 c1ltxA_ not modelled 97.6 9 PDB header:transferase/protein binding Chain: A: PDB Molecule:rab geranylgeranyltransferase alpha subunit; PDBTitle: structure of rab escort protein-1 in complex with rab2 geranylgeranyl transferase and isoprenoid 102 c3nf1A_ not modelled 97.6 19 PDB header:motor protein, transport protein Chain: A: PDB Molecule:kinesin light chain 1; PDBTitle: crystal structure of the tpr domain of kinesin light chain 1 103 c3e4bD_ not modelled 97.4 16 PDB header:protein binding Chain: D: PDB Molecule:algk; PDBTitle: crystal structure of algk from pseudomonas fluorescens wcs374r 104 c2xm6A_ not modelled 96.7 17 PDB header:unknown function Chain: A: PDB Molecule:protein corresponding to locus c5321 from cft073 e.coli PDBTitle: crystal structure of the protein corresponding to locus c5321 from2 cft073 e.coli strain 105 c3q3hA_ not modelled 96.2 7 PDB header:transferase Chain: A: PDB Molecule:hmw1c-like glycosyltransferase; PDBTitle: crystal structure of the actinobacillus pleuropneumoniae hmw1c2 glycosyltransferase in complex with udp-glc 106 d1ouva_ not modelled 96.1 15 Fold:alpha-alpha superhelix Superfamily:HCP-like Family:HCP-like 107 d1iipa1 not modelled 96.1 21 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 108 c2lahA_ not modelled 95.2 10 PDB header:cell cycle, apoptosis Chain: A: PDB Molecule:mitotic checkpoint serine/threonine-protein kinase bub1; PDBTitle: solution nmr structure of mitotic checkpoint serine/threonine-protein2 kinase bub1 n-terminal domain from homo sapiens, northeast structural3 genomics consortium target hr5460a (methods development) 109 c2ff4B_ not modelled 95.2 15 PDB header:transcription Chain: B: PDB Molecule:probable regulatory protein embr; PDBTitle: mycobacterium tuberculosis embr in complex with low affinity2 phosphopeptide 110 c3txmA_ not modelled 94.5 16 PDB header:hydrolase, protein binding Chain: A: PDB Molecule:26s proteasome regulatory complex subunit p42b; PDBTitle: crystal structure of rpn6 from drosophila melanogaster, gd(3+) complex 111 c2wviA_ not modelled 93.7 8 PDB header:transferase Chain: A: PDB Molecule:mitotic checkpoint serine/threonine-protein PDBTitle: crystal structure of the n-terminal domain of bubr1 112 c2v6yA_ not modelled 92.7 9 PDB header:hydrolase Chain: A: PDB Molecule:aaa family atpase, p60 katanin; PDBTitle: structure of the mit domain from a s. solfataricus vps4-2 like atpase 113 c2w2uA_ not modelled 92.0 12 PDB header:hydrolase/transport Chain: A: PDB Molecule:hypothetical p60 katanin; PDBTitle: structural insight into the interaction between archaeal2 escrt-iii and aaa-atpase 114 c3rjvA_ not modelled 91.6 16 PDB header:protein binding Chain: A: PDB Molecule:putative sel1 repeat protein; PDBTitle: crystal structure of a putative sel1 repeat protein (kpn_04481) from2 klebsiella pneumoniae subsp. pneumoniae at 1.65 a resolution 115 d2crba1 not modelled 85.7 22 Fold:Spectrin repeat-like Superfamily:MIT domain-like Family:MIT domain 116 c3lvhA_ not modelled 84.5 13 PDB header:structural protein Chain: A: PDB Molecule:clathrin heavy chain 1; PDBTitle: crystal structure of a clathrin heavy chain and clathrin light chain2 complex 117 c2v1sD_ not modelled 75.3 23 PDB header:oxidoreductase Chain: D: PDB Molecule:mitochondrial import receptor subunit tom20 homolog; PDBTitle: crystal structure of rat tom20-aldh presequence complex 118 d1wfda_ not modelled 74.9 20 Fold:Spectrin repeat-like Superfamily:MIT domain Family:MIT domain 119 c2dl1A_ not modelled 73.4 18 PDB header:protein transport Chain: A: PDB Molecule:spartin; PDBTitle: solution structure of the mit domain from human spartin 120 c3hd7A_ 73.3 21 PDB header:exocytosis Chain: A: PDB Molecule:vesicle-associated membrane protein 2; PDBTitle: helical extension of the neuronal snare complex into the membrane,2 spacegroup c 1 2 1

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0