Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	M	P	T	L	A	P	P	S	V	L	S	A	P	Q	R	R	C	Q	I	L	L	T	L	F	Q	P	G	L	T	A	T	M	A	T	F	S	E	L	N	G	V	D	D	D	I	A	S	L	D	I	S	E	T	G	R	E	I	L	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Y	H	Q	L	T	L	T	T	G	Y	D	G	S	Y	R	V	E	G	T	V	L	N	Q	R	L	C	L	F	H	W	L	R	R	G	F	R	L	C	P	S	F	I	T	S	Q	F	T	P	A	L	K	S	E	L	K	R	R	G	I	A
Secondary structure
SS confidence
Disorder																																						?	?	?																	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		R	N	F	Y	D	D	T	N	L	Q	A	L	V	N	L	C	S	R	R	L	Q	K	R	F	E	S	R	D	I	H	F	L	C	L	Y	L	Q	Y	C	L	L	Q	H	H	A	G	I	T	P	Q	F	N	P	L	Q	R	R	W	A	E
Secondary structure
SS confidence
Disorder																																														?		?	?	?	?	?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		S	C	L	E	F	Q	V	A	Q	E	I	G	R	H	W	Q	R	R	A	L	Q	P	V	P	P	D	E	P	L	F	M	A	L	L	F	S	M	L	R	V	P	D	P	L	R	D	A	H	Q	R	D	R	Q	L	R	Q	S	I	K	R
Secondary structure
SS confidence
Disorder																																							?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		L	V	N	H	F	R	E	L	G	N	V	R	F	Y	D	E	Q	G	L	C	D	Q	L	Y	T	H	L	A	Q	A	L	N	R	S	L	F	A	I	G	I	D	N	T	L	P	E	E	F	A	R	L	Y	P	R	L	V	R	T	T	R
Secondary structure
SS confidence
Disorder																																					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		A	A	L	A	G	F	E	S	E	Y	G	V	H	L	S	D	E	E	S	G	L	V	A	V	I	F	G	A	W	L	M	Q	E	N	D	L	H	E	K	Q	I	I	L	L	T	G	N	D	S	E	R	E	A	Q	I	E	Q	Q	L	R
Secondary structure
SS confidence
Disorder																																	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		E	L	T	L	L	P	L	N	I	K	H	M	S	V	K	A	F	L	Q	T	G	A	P	R	G	A	A	L	I	I	A	P	Y	T	M	P	L	P	L	F	S	P	P	L	I	Y	T	D	L	T	L	T	T	H	Q	Q	E	Q	I	R
Secondary structure
SS confidence
Disorder			?																	?	?																?	?
Disorder confidence
		.	.	.	.	.	.
Sequence		K	M	L	E	S	A
Secondary structure
SS confidence
Disorder					?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3sqn chain B Region: 13 - 423 Aligned: 375 Modelled: 391 Confidence: 100.0% Identity: 13% PDB header:transcription regulator Chain: B: PDB Molecule:conserved domain protein; PDBTitle: putative mga family transcriptional regulator from enterococcus2 faecalis Phyre2 PDB 1h99 chain A Region: 122 - 331 Aligned: 206 Modelled: 210 Confidence: 100.0% Identity: 14% PDB header:transcriptional antiterminator Chain: A: PDB Molecule:transcription antiterminator lict; PDBTitle: prd of lict antiterminator from bacillus subtilis Phyre2 PDB 1h99 chain A domain 2 Region: 229 - 331 Aligned: 103 Modelled: 103 Confidence: 99.7% Identity: 14% Fold: PTS-regulatory domain, PRD Superfamily: PTS-regulatory domain, PRD Family: PTS-regulatory domain, PRD Phyre2 PDB 3gwh chain B Region: 235 - 329 Aligned: 95 Modelled: 95 Confidence: 99.6% Identity: 13% PDB header:transcription Chain: B: PDB Molecule:transcriptional antiterminator (bglg family); PDBTitle: crystallographic ab initio protein solution far below atomic2 resolution Phyre2 PDB 1h99 chain A domain 1 Region: 231 - 329 Aligned: 97 Modelled: 99 Confidence: 99.6% Identity: 20% Fold: PTS-regulatory domain, PRD Superfamily: PTS-regulatory domain, PRD Family: PTS-regulatory domain, PRD Phyre2 PDB 1tvm chain A Region: 335 - 424 Aligned: 90 Modelled: 90 Confidence: 99.2% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:pts system, galactitol-specific iib component; PDBTitle: nmr structure of enzyme gatb of the galactitol-specific2 phosphoenolpyruvate-dependent phosphotransferase system Phyre2 PDB 3czc chain A Region: 339 - 424 Aligned: 86 Modelled: 86 Confidence: 98.9% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:rmpb; PDBTitle: the crystal structure of a putative pts iib(ptxb) from2 streptococcus mutans Phyre2 PDB 1vkr chain A Region: 337 - 423 Aligned: 86 Modelled: 87 Confidence: 98.9% Identity: 14% Fold: Phosphotyrosine protein phosphatases I-like Superfamily: PTS system IIB component-like Family: PTS system, Lactose/Cellobiose specific IIB subunit Phyre2 PDB 1vkr chain A Region: 337 - 423 Aligned: 86 Modelled: 87 Confidence: 98.9% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:mannitol-specific pts system enzyme iiabc components; PDBTitle: structure of iib domain of the mannitol-specific permease enzyme ii Phyre2 PDB 1j5y chain A domain 1 Region: 13 - 78 Aligned: 60 Modelled: 66 Confidence: 98.6% Identity: 18% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Biotin repressor-like Phyre2 PDB 1j5y chain A Region: 13 - 80 Aligned: 62 Modelled: 68 Confidence: 98.5% Identity: 18% PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator, biotin repressor family; PDBTitle: crystal structure of transcriptional regulator (tm1602) from2 thermotoga maritima at 2.3 a resolution Phyre2 PDB 1bia chain A domain 1 Region: 11 - 76 Aligned: 60 Modelled: 66 Confidence: 98.3% Identity: 15% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Biotin repressor-like Phyre2 PDB 1o57 chain A domain 1 Region: 11 - 77 Aligned: 67 Modelled: 67 Confidence: 97.1% Identity: 16% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: N-terminal domain of Bacillus PurR Phyre2 PDB 2ewn chain A Region: 21 - 79 Aligned: 54 Modelled: 59 Confidence: 97.0% Identity: 19% PDB header:ligase, transcription Chain: A: PDB Molecule:bira bifunctional protein; PDBTitle: ecoli biotin repressor with co-repressor analog Phyre2 PDB 3neu chain A Region: 3 - 95 Aligned: 87 Modelled: 90 Confidence: 96.9% Identity: 9% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:lin1836 protein; PDBTitle: the crystal structure of a functionally-unknown protein lin1836 from2 listeria innocua clip11262 Phyre2 PDB 3nuf chain B Region: 231 - 329 Aligned: 92 Modelled: 99 Confidence: 96.7% Identity: 23% PDB header:transcription regulator Chain: B: PDB Molecule:prd-containing transcription regulator; PDBTitle: crystal structure of a prd-containing transcription regulator2 (lsei_2718) from lactobacillus casei atcc 334 at 1.38 a resolution Phyre2 PDB 3by6 chain C Region: 17 - 95 Aligned: 73 Modelled: 79 Confidence: 96.5% Identity: 5% PDB header:transcription regulator Chain: C: PDB Molecule:predicted transcriptional regulator; PDBTitle: crystal structure of a transcriptional regulator from oenococcus oeni Phyre2 PDB 1f5t chain A Region: 12 - 78 Aligned: 61 Modelled: 67 Confidence: 96.4% Identity: 16% PDB header:transcription/dna Chain: A: PDB Molecule:diphtheria toxin repressor; PDBTitle: diphtheria tox repressor (c102d mutant) complexed with2 nickel and dtxr consensus binding sequence Phyre2 PDB 1stz chain A domain 1 Region: 10 - 92 Aligned: 76 Modelled: 78 Confidence: 96.4% Identity: 14% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Heat-inducible transcription repressor HrcA, N-terminal domain Phyre2 PDB 1o57 chain A Region: 11 - 106 Aligned: 96 Modelled: 95 Confidence: 96.2% Identity: 13% PDB header:dna binding protein Chain: A: PDB Molecule:pur operon repressor; PDBTitle: crystal structure of the purine operon repressor of2 bacillus subtilis Phyre2 PDB 2l4a chain A Region: 1 - 56 Aligned: 53 Modelled: 53 Confidence: 96.0% Identity: 17% PDB header:dna binding protein Chain: A: PDB Molecule:leucine responsive regulatory protein; PDBTitle: nmr structure of the dna-binding domain of e.coli lrp Phyre2 1 c3sqnB_ 2 c1h99A_ 3 d1h99a2 4 c3gwhB_ 5 d1h99a1 6 c1tvmA_ 7 c3czcA_ 8 d1vkra_ 9 c1vkrA_ 10 d1j5ya1 11 c1j5yA_ 12 d1biaa1 13 d1o57a1 14 c2ewnA_ 15 c3neuA_ 16 c3nufB_ 17 c3by6C_ 18 c1f5tA_ 19 d1stza1 20 c1o57A_ 21 22 23 c2l4aA_ 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499