Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP32055
DateThu Jan 5 11:49:02 GMT 2012
Unique Job ID707f90d19237c949

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1e6ua_
Top template information
Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
Confidence and coverage
Confidence:100.0% Coverage: 98%
315 residues ( 98% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MSKQRVFIAGHRGMVGSAIRRQLEQRGDVELVLRTRDELNLLDSRAVHDFFASERIDQVY
Secondary structure 
SS confidence 
Disorder  ????
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  LAAAKVGGIVANNTYPADFIYQNMMIESNIIHAAHQNDVNKLLFLGSSCIYPKLAKQPMA
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  ESELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRSVMPTNLYGPHDNFHPSNSHV
Secondary structure 
SS confidence 
Disorder 
??
?
????????
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  IPALLRRFHEATAQNAPDVVVWGSGTPMREFLHVDDMAAASIHVMELAHEVWLENTQPML
Secondary structure 
SS confidence 
Disorder 
??
??????????
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  SHINVGTGVDCTIRELAQTIAKVVGYKGRVVFDASKPDGTPRKLLDVTRLHQLGWYHEIS
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........310.........320.
Sequence  LEAGLASTYQWFLENQDRFRG
Secondary structure 
SS confidence 
Disorder 
????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1e6u chain A

3D model

Region: 2 - 316
Aligned: 315
Modelled: 315
Confidence: 100.0%
Identity: 99%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1z45 chain A

3D model

Region: 3 - 320
Aligned: 305
Modelled: 318
Confidence: 100.0%
Identity: 20%
PDB header:isomerase
Chain: A: PDB Molecule:gal10 bifunctional protein;
PDBTitle: crystal structure of the gal10 fusion protein galactose2 mutarotase/udp-galactose 4-epimerase from saccharomyces3 cerevisiae complexed with nad, udp-glucose, and galactose

Phyre2

PDB 1z7e chain C

3D model

Region: 1 - 315
Aligned: 305
Modelled: 315
Confidence: 100.0%
Identity: 16%
PDB header:hydrolase
Chain: C: PDB Molecule:protein arna;
PDBTitle: crystal structure of full length arna

Phyre2

PDB 1i24 chain A

3D model

Region: 3 - 320
Aligned: 311
Modelled: 317
Confidence: 100.0%
Identity: 16%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 3enk chain B

3D model

Region: 1 - 319
Aligned: 308
Modelled: 319
Confidence: 100.0%
Identity: 20%
PDB header:isomerase
Chain: B: PDB Molecule:udp-glucose 4-epimerase;
PDBTitle: 1.9a crystal structure of udp-glucose 4-epimerase from2 burkholderia pseudomallei

Phyre2

PDB 1ek6 chain A

3D model

Region: 1 - 320
Aligned: 309
Modelled: 317
Confidence: 100.0%
Identity: 21%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1orr chain A

3D model

Region: 5 - 314
Aligned: 304
Modelled: 310
Confidence: 100.0%
Identity: 15%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 2c5a chain A domain 1

3D model

Region: 2 - 318
Aligned: 300
Modelled: 317
Confidence: 100.0%
Identity: 24%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 2b69 chain A

3D model

Region: 3 - 318
Aligned: 295
Modelled: 297
Confidence: 100.0%
Identity: 22%
PDB header:lyase
Chain: A: PDB Molecule:udp-glucuronate decarboxylase 1;
PDBTitle: crystal structure of human udp-glucoronic acid decarboxylase

Phyre2

PDB 2b69 chain A domain 1

3D model

Region: 3 - 318
Aligned: 295
Modelled: 294
Confidence: 100.0%
Identity: 22%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1gy8 chain A

3D model

Region: 2 - 315
Aligned: 311
Modelled: 314
Confidence: 100.0%
Identity: 19%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 2hun chain B

3D model

Region: 1 - 320
Aligned: 295
Modelled: 306
Confidence: 100.0%
Identity: 20%
PDB header:lyase
Chain: B: PDB Molecule:336aa long hypothetical dtdp-glucose 4,6-dehydratase;
PDBTitle: crystal structure of hypothetical protein ph0414 from pyrococcus2 horikoshii ot3

Phyre2

PDB 1n7g chain B

3D model

Region: 3 - 318
Aligned: 299
Modelled: 316
Confidence: 100.0%
Identity: 16%
PDB header:lyase
Chain: B: PDB Molecule:gdp-d-mannose-4,6-dehydratase;
PDBTitle: crystal structure of the gdp-mannose 4,6-dehydratase2 ternary complex with nadph and gdp-rhamnose.

Phyre2

PDB 2c20 chain D

3D model

Region: 5 - 320
Aligned: 304
Modelled: 311
Confidence: 100.0%
Identity: 18%
PDB header:isomerase
Chain: D: PDB Molecule:udp-glucose 4-epimerase;
PDBTitle: crystal structure of udp-glucose 4-epimerase

Phyre2

PDB 1db3 chain A

3D model

Region: 3 - 318
Aligned: 298
Modelled: 316
Confidence: 100.0%
Identity: 20%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1wvg chain A domain 1

3D model

Region: 2 - 317
Aligned: 298
Modelled: 316
Confidence: 100.0%
Identity: 16%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1n7h chain A

3D model

Region: 3 - 318
Aligned: 299
Modelled: 316
Confidence: 100.0%
Identity: 17%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 3lu1 chain C

3D model

Region: 1 - 318
Aligned: 298
Modelled: 317
Confidence: 100.0%
Identity: 22%
PDB header:isomerase
Chain: C: PDB Molecule:wbgu;
PDBTitle: crystal structure analysis of wbgu: a udp-galnac 4-epimerase

Phyre2

PDB 1oc2 chain A

3D model

Region: 4 - 321
Aligned: 296
Modelled: 309
Confidence: 100.0%
Identity: 18%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1z45 chain A domain 2

3D model

Region: 3 - 320
Aligned: 306
Modelled: 309
Confidence: 100.0%
Identity: 20%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2
1
d1e6ua_
2
c1z45A_
3
c1z7eC_
4
d1i24a_
5
c3enkB_
6
d1ek6a_
7
d1orra_
8
d2c5aa1
9
c2b69A_
10
d2b69a1
11
d1gy8a_
12
c2hunB_
13
c1n7gB_
14
c2c20D_
15
d1db3a_
16
d1wvga1
17
d1n7ha_
18
c3lu1C_
19
d1oc2a_
20
d1z45a2
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
438
439
440
441
442
443
444
445
446
447
448
449
450
451
452
453
454
455
456
457
458
459
460
461
462
463
464
465
466
467
468
469
470
471
472
473
474
475
476
477
478
479
480
481
482
483
484
485
486
487
488
489
490
491
492
493
494
495
496
497
498
499



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1e6ua_
100.0 99 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
2c1z45A_
100.0 20 PDB header:isomerase
Chain: A: PDB Molecule:gal10 bifunctional protein;
PDBTitle: crystal structure of the gal10 fusion protein galactose2 mutarotase/udp-galactose 4-epimerase from saccharomyces3 cerevisiae complexed with nad, udp-glucose, and galactose
3c1z7eC_
100.0 16 PDB header:hydrolase
Chain: C: PDB Molecule:protein arna;
PDBTitle: crystal structure of full length arna
4d1i24a_
100.0 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
5c3enkB_
100.0 20 PDB header:isomerase
Chain: B: PDB Molecule:udp-glucose 4-epimerase;
PDBTitle: 1.9a crystal structure of udp-glucose 4-epimerase from2 burkholderia pseudomallei
6d1ek6a_
100.0 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
7d1orra_
100.0 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
8d2c5aa1
100.0 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
9c2b69A_
100.0 22 PDB header:lyase
Chain: A: PDB Molecule:udp-glucuronate decarboxylase 1;
PDBTitle: crystal structure of human udp-glucoronic acid decarboxylase
10d2b69a1
100.0 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
11d1gy8a_
100.0 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
12c2hunB_
100.0 20 PDB header:lyase
Chain: B: PDB Molecule:336aa long hypothetical dtdp-glucose 4,6-dehydratase;
PDBTitle: crystal structure of hypothetical protein ph0414 from pyrococcus2 horikoshii ot3
13c1n7gB_
100.0 16 PDB header:lyase
Chain: B: PDB Molecule:gdp-d-mannose-4,6-dehydratase;
PDBTitle: crystal structure of the gdp-mannose 4,6-dehydratase2 ternary complex with nadph and gdp-rhamnose.
14c2c20D_
100.0 18 PDB header:isomerase
Chain: D: PDB Molecule:udp-glucose 4-epimerase;
PDBTitle: crystal structure of udp-glucose 4-epimerase
15d1db3a_
100.0 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
16d1wvga1
100.0 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
17d1n7ha_
100.0 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
18c3lu1C_
100.0 22 PDB header:isomerase
Chain: C: PDB Molecule:wbgu;
PDBTitle: crystal structure analysis of wbgu: a udp-galnac 4-epimerase
19d1oc2a_
100.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
20d1z45a2
100.0 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
21c2z1mC_
not modelled 100.0 19 PDB header:lyase
Chain: C: PDB Molecule:gdp-d-mannose dehydratase;
PDBTitle: crystal structure of gdp-d-mannose dehydratase from aquifex aeolicus2 vf5
22d1kewa_
not modelled 100.0 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
23d1rkxa_
not modelled 100.0 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
24d1bxka_
not modelled 100.0 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
25c2pk3B_
not modelled 100.0 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:gdp-6-deoxy-d-lyxo-4-hexulose reductase;
PDBTitle: crystal structure of a gdp-4-keto-6-deoxy-d-mannose reductase
26c2p5uC_
not modelled 100.0 24 PDB header:isomerase
Chain: C: PDB Molecule:udp-glucose 4-epimerase;
PDBTitle: crystal structure of thermus thermophilus hb8 udp-glucose 4-2 epimerase complex with nad
27d1rpna_
not modelled 100.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
28c2q1uA_
not modelled 100.0 20 PDB header:sugar binding protein
Chain: A: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase;
PDBTitle: crystal structure of the bordetella bronchiseptica enzyme wbmf in2 complex with nad+ and udp
29d1udca_
not modelled 100.0 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
30d2blla1
not modelled 100.0 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
31d1t2aa_
not modelled 100.0 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
32d1r6da_
not modelled 100.0 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
33c1t2aC_
not modelled 100.0 15 PDB header:structural genomics,lyase
Chain: C: PDB Molecule:gdp-mannose 4,6 dehydratase;
PDBTitle: crystal structure of human gdp-d-mannose 4,6-dehydratase
34c2yy7B_
not modelled 100.0 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:l-threonine dehydrogenase;
PDBTitle: crystal structure of thermolabile l-threonine dehydrogenase from2 flavobacterium frigidimaris kuc-1
35d1sb8a_
not modelled 100.0 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
36c2hrzA_
not modelled 100.0 14 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:nucleoside-diphosphate-sugar epimerase;
PDBTitle: the crystal structure of the nucleoside-diphosphate-sugar epimerase2 from agrobacterium tumefaciens
37c3slgB_
not modelled 100.0 14 PDB header:transferase
Chain: B: PDB Molecule:pbgp3 protein;
PDBTitle: crystal structure of pbgp3 protein from burkholderia pseudomallei
38c3a1nB_
not modelled 100.0 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:ndp-sugar epimerase;
PDBTitle: crystal structure of l-threonine dehydrogenase from2 hyperthermophilic archaeon thermoplasma volcanium
39c2p4hX_
not modelled 100.0 19 PDB header:plant protein
Chain: X: PDB Molecule:vestitone reductase;
PDBTitle: crystal structure of vestitone reductase from alfalfa2 (medicago sativa l.)
40c3eheB_
not modelled 100.0 18 PDB header:isomerase
Chain: B: PDB Molecule:udp-glucose 4-epimerase (gale-1);
PDBTitle: crystal structure of udp-glucose 4 epimerase (gale-1) from2 archaeoglobus fulgidus
41c2iodD_
not modelled 100.0 17 PDB header:oxidoreductase
Chain: D: PDB Molecule:dihydroflavonol 4-reductase;
PDBTitle: binding of two substrate analogue molecules to2 dihydroflavonol-4-reductase alters the functional geometry3 of the catalytic site
42c2pzlB_
not modelled 100.0 21 PDB header:sugar binding protein
Chain: B: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase;
PDBTitle: crystal structure of the bordetella bronchiseptica enzyme2 wbmg in complex with nad and udp
43c2q1wC_
not modelled 100.0 22 PDB header:sugar binding protein
Chain: C: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase;
PDBTitle: crystal structure of the bordetella bronchiseptica enzyme wbmh in2 complex with nad+
44c2x4gA_
not modelled 100.0 16 PDB header:isomerase
Chain: A: PDB Molecule:nucleoside-diphosphate-sugar epimerase;
PDBTitle: crystal structure of pa4631, a nucleoside-diphosphate-sugar2 epimerase from pseudomonas aeruginosa
45c2rh8A_
not modelled 100.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:anthocyanidin reductase;
PDBTitle: structure of apo anthocyanidin reductase from vitis vinifera
46c2v6gA_
not modelled 100.0 11 PDB header:oxidoreductase
Chain: A: PDB Molecule:progesterone 5-beta-reductase;
PDBTitle: structure of progesterone 5beta-reductase from digitalis2 lanata in complex with nadp
47c3sc6F_
not modelled 100.0 17 PDB header:oxidoreductase
Chain: F: PDB Molecule:dtdp-4-dehydrorhamnose reductase;
PDBTitle: 2.65 angstrom resolution crystal structure of dtdp-4-dehydrorhamnose2 reductase (rfbd) from bacillus anthracis str. ames in complex with3 nadp
48c2ydyA_
not modelled 100.0 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:methionine adenosyltransferase 2 subunit beta;
PDBTitle: crystal structure of human s-adenosylmethionine synthetase2 2, beta subunit in orthorhombic crystal form
49d1vl0a_
not modelled 100.0 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
50c3m2pD_
not modelled 100.0 18 PDB header:isomerase
Chain: D: PDB Molecule:udp-n-acetylglucosamine 4-epimerase;
PDBTitle: the crystal structure of udp-n-acetylglucosamine 4-epimerase2 from bacillus cereus
51c3icpA_
not modelled 100.0 25 PDB header:isomerase
Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: crystal structure of udp-galactose 4-epimerase
52d1y1pa1
not modelled 100.0 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
53d1n2sa_
not modelled 100.0 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
54c2x86K_
not modelled 100.0 16 PDB header:isomerase
Chain: K: PDB Molecule:adp-l-glycero-d-manno-heptose-6-epimerase;
PDBTitle: agme bound to adp-b-mannose
55c3oh8A_
not modelled 100.0 13 PDB header:isomerase
Chain: A: PDB Molecule:nucleoside-diphosphate sugar epimerase (sula family);
PDBTitle: crystal structure of the nucleoside-diphosphate sugar epimerase from2 corynebacterium glutamicum. northeast structural genomics consortium3 target cgr91
56c3gpiA_
not modelled 100.0 16 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: structure of putative nad-dependent epimerase/dehydratase2 from methylobacillus flagellatus
57d1eq2a_
not modelled 100.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
58c2ggsB_
not modelled 99.9 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:273aa long hypothetical dtdp-4-dehydrorhamnose
PDBTitle: crystal structure of hypothetical dtdp-4-dehydrorhamnose2 reductase from sulfolobus tokodaii
59c3iusB_
not modelled 99.9 12 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized conserved protein;
PDBTitle: the structure of a functionally unknown conserved protein2 from silicibacter pomeroyi dss
60c2gn9B_
not modelled 99.9 18 PDB header:lyase
Chain: B: PDB Molecule:udp-glcnac c6 dehydratase;
PDBTitle: crystal structure of udp-glcnac inverting 4,6-dehydratase in complex2 with nadp and udp-glc
61c2zklA_
not modelled 99.9 21 PDB header:isomerase
Chain: A: PDB Molecule:capsular polysaccharide synthesis enzyme cap5f;
PDBTitle: crystal structure of capsular polysaccharide assembling protein capf2 from staphylococcus aureus
62c3e48B_
not modelled 99.9 16 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative nucleoside-diphosphate-sugar epimerase;
PDBTitle: crystal structure of a nucleoside-diphosphate-sugar epimerase2 (sav0421) from staphylococcus aureus, northeast structural genomics3 consortium target zr319
63c2qx7A_
not modelled 99.9 17 PDB header:plant protein
Chain: A: PDB Molecule:eugenol synthase 1;
PDBTitle: structure of eugenol synthase from ocimum basilicum
64d1qyca_
not modelled 99.9 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
65c3nzoB_
not modelled 99.9 13 PDB header:lyase
Chain: B: PDB Molecule:udp-n-acetylglucosamine 4,6-dehydratase;
PDBTitle: udp-n-acetylglucosamine 4,6-dehydratase from vibrio fischeri.
66c2exxB_
not modelled 99.9 18 PDB header:unknown function
Chain: B: PDB Molecule:hscarg protein;
PDBTitle: crystal structure of hscarg from homo sapiens in complex with nadp
67c3c1oA_
not modelled 99.9 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:eugenol synthase;
PDBTitle: the multiple phenylpropene synthases in both clarkia2 breweri and petunia hybrida represent two distinct lineages
68d1xgka_
not modelled 99.9 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
69d1qyda_
not modelled 99.9 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
70c2gasA_
not modelled 99.9 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:isoflavone reductase;
PDBTitle: crystal structure of isoflavone reductase
71c3ay3C_
not modelled 99.9 23 PDB header:oxidoreductase
Chain: C: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: crystal structure of glucuronic acid dehydrogeanse from2 chromohalobacter salexigens
72c3i5mA_
not modelled 99.9 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative leucoanthocyanidin reductase 1;
PDBTitle: structure of the apo form of leucoanthocyanidin reductase from vitis2 vinifera
73c3rfxB_
not modelled 99.9 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:uronate dehydrogenase;
PDBTitle: crystal structure of uronate dehydrogenase from agrobacterium2 tumefaciens, y136a mutant complexed with nad
74c2zcuA_
not modelled 99.9 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:uncharacterized oxidoreductase ytfg;
PDBTitle: crystal structure of a new type of nadph-dependent quinone2 oxidoreductase (qor2) from escherichia coli
75c2vrcD_
not modelled 99.8 16 PDB header:oxidoreductase
Chain: D: PDB Molecule:triphenylmethane reductase;
PDBTitle: crystal structure of the citrobacter sp. triphenylmethane2 reductase complexed with nadp(h)
76d1hdoa_
not modelled 99.8 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
77c3e8xA_
not modelled 99.8 19 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative nad-dependent epimerase/dehydratase;
PDBTitle: putative nad-dependent epimerase/dehydratase from bacillus halodurans.
78d2q46a1
not modelled 99.8 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
79c3dhnA_
not modelled 99.8 19 PDB header:isomerase, lyase
Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: crystal structure of the putative epimerase q89z24_bactn2 from bacteroides thetaiotaomicron. northeast structural3 genomics consortium target btr310.
80c3h2sA_
not modelled 99.7 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative nadh-flavin reductase;
PDBTitle: crystal structure of the q03b84 protein from lactobacillus2 casei. northeast structural genomics consortium target3 lcr19.
81c3dqpA_
not modelled 99.7 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase ylbe;
PDBTitle: crystal structure of the oxidoreductase ylbe from2 lactococcus lactis, northeast structural genomics3 consortium target kr121.
82d2bkaa1
not modelled 99.7 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
83c3qvoA_
not modelled 99.7 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:nmra family protein;
PDBTitle: structure of a rossmann-fold nad(p)-binding family protein from2 shigella flexneri.
84d2a35a1
not modelled 99.6 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
85d2fmua1
not modelled 99.6 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
86c3ew7A_
not modelled 99.6 19 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:lmo0794 protein;
PDBTitle: crystal structure of the lmo0794 protein from listeria2 monocytogenes. northeast structural genomics consortium3 target lmr162.
87c2jahB_
not modelled 99.4 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:clavulanic acid dehydrogenase;
PDBTitle: biochemical and structural analysis of the clavulanic acid2 dehydeogenase (cad) from streptomyces clavuligerus
88d1mlda1
not modelled 99.3 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
89c3r6dA_
not modelled 99.3 14 PDB header:lyase, isomerase
Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: crystal structure of nad-dependent epimerase/dehydratase from2 veillonella parvula dsm 2008 with cz-methylated lysine
90d1hyea1
not modelled 99.2 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
91d1ooea_
not modelled 99.1 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
92c2dteB_
not modelled 99.1 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:glucose 1-dehydrogenase related protein;
PDBTitle: structure of thermoplasma acidophilum aldohexose dehydrogenase (aldt)2 in complex with nadh
93c3lylB_
not modelled 99.1 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-oxoacyl-(acyl-carrier-protein) reductase;
PDBTitle: structure of 3-oxoacyl-acylcarrier protein reductase, fabg2 from francisella tularensis
94c3un1D_
not modelled 99.1 12 PDB header:oxidoreductase
Chain: D: PDB Molecule:probable oxidoreductase;
PDBTitle: crystal structure of an oxidoreductase from sinorhizobium meliloti2 1021
95c2yutA_
not modelled 99.1 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative short-chain oxidoreductase;
PDBTitle: crystal structure of putative short-chain oxidoreductase tthb094 from2 thermus thermophilus hb8
96c3p19A_
not modelled 99.1 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative blue fluorescent protein;
PDBTitle: improved nadph-dependent blue fluorescent protein
97c2qioA_
not modelled 99.1 9 PDB header:unknown function
Chain: A: PDB Molecule:enoyl-(acyl-carrier-protein) reductase;
PDBTitle: x-ray structure of enoyl-acyl carrier protein reductase from bacillus2 anthracis with triclosan
98c3toxG_
not modelled 99.0 15 PDB header:oxidoreductase
Chain: G: PDB Molecule:short chain dehydrogenase;
PDBTitle: crystal structure of a short chain dehydrogenase in complex with2 nad(p) from sinorhizobium meliloti 1021
99d1qsga_
not modelled 99.0 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
100c3ioyB_
not modelled 99.0 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: structure of putative short-chain dehydrogenase (saro_0793)2 from novosphingobium aromaticivorans
101c2p68A_
not modelled 99.0 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of aq_1716 from aquifex aeolicus vf5
102d2gdza1
not modelled 99.0 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
103c2q2qG_
not modelled 99.0 12 PDB header:oxidoreductase
Chain: G: PDB Molecule:beta-d-hydroxybutyrate dehydrogenase;
PDBTitle: structure of d-3-hydroxybutyrate dehydrogenase from pseudomonas putida
104c3ctmH_
not modelled 99.0 17 PDB header:oxidoreductase
Chain: H: PDB Molecule:carbonyl reductase;
PDBTitle: crystal structure of a carbonyl reductase from candida2 parapsilosis with anti-prelog stereo-specificity
105c2nm0B_
not modelled 99.0 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:probable 3-oxacyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of sco1815: a beta-ketoacyl-acyl carrier protein2 reductase from streptomyces coelicolor a3(2)
106d1sbya1
not modelled 99.0 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
107c3rkrC_
not modelled 99.0 20 PDB header:oxidoreductase
Chain: C: PDB Molecule:short chain oxidoreductase;
PDBTitle: crystal structure of a metagenomic short-chain oxidoreductase (sdr) in2 complex with nadp
108d2ae2a_
not modelled 99.0 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
109d1geea_
not modelled 99.0 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
110d2pd4a1
not modelled 99.0 9 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
111c3l77A_
not modelled 99.0 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:short-chain alcohol dehydrogenase;
PDBTitle: x-ray structure alcohol dehydrogenase from archaeon thermococcus2 sibiricus complexed with 5-hydroxy-nadp
112c3t7cC_
not modelled 99.0 13 PDB header:oxidoreductase
Chain: C: PDB Molecule:carveol dehydrogenase;
PDBTitle: crystal structure of carveol dehydrogenase from mycobacterium avium2 bound to nad
113c3iccA_
not modelled 99.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative 3-oxoacyl-(acyl carrier protein) reductase;
PDBTitle: crystal structure of a putative 3-oxoacyl-(acyl carrier protein)2 reductase from bacillus anthracis at 1.87 a resolution
114c3l6eA_
not modelled 99.0 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase, short-chain dehydrogenase/reductase family;
PDBTitle: crystal structure of putative short chain dehydrogenase/reductase2 family oxidoreductase from aeromonas hydrophila subsp. hydrophila3 atcc 7966
115d1zk4a1
not modelled 99.0 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
116d2ew8a1
not modelled 99.0 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
117c2hlpB_
not modelled 99.0 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:malate dehydrogenase;
PDBTitle: crystal structure of the e267r mutant of a halophilic2 malate dehydrogenase in the apo form
118c3pgxB_
not modelled 99.0 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:carveol dehydrogenase;
PDBTitle: crystal structure of a putative carveol dehydrogenase from2 mycobacterium paratuberculosis bound to nicotinamide adenine3 dinucleotide
119c2cfcB_
not modelled 99.0 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:2-(r)-hydroxypropyl-com dehydrogenase;
PDBTitle: structural basis for stereo selectivity in the (r)- and2 (s)-hydroxypropylethane thiosulfonate dehydrogenases
120c3gr6A_
not modelled 99.0 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:enoyl-[acyl-carrier-protein] reductase [nadh];
PDBTitle: crystal structure of the staphylococcus aureus enoyl-acyl2 carrier protein reductase (fabi) in complex with nadp and3 triclosan

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0