Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0AG07
DateThu Jan 5 11:27:45 GMT 2012
Unique Job ID6bb630ee8537a734

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3cu2A_
Top template information
PDB header:isomerase
Chain: A: PDB Molecule:ribulose-5-phosphate 3-epimerase;
PDBTitle: crystal structure of ribulose-5-phosphate 3-epimerase (yp_718263.1)2 from haemophilus somnus 129pt at 1.91 a resolution
Confidence and coverage
Confidence:100.0% Coverage: 96%
215 residues ( 96% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVPNLTIGPMVLKSLRNYG
Secondary structure 




















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Disorder  ?????
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   .........70.........80.........90.........100.........110.........120
Sequence  ITAPIDVHLMVKPVDRIVPDFAAAGASIITFHPEASEHVDRTLQLIKENGCKAGLVFNPA
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   .........130.........140.........150.........160.........170.........180
Sequence  TPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLREVRRRIDESGFDIRLEVDGGV
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   .........190.........200.........210.........220.....
Sequence  KVNNIGEIAAAGADMFVAGSAIFDQPDYKKVIDEMRSELAKVSHE
Secondary structure 











SS confidence 












































Disorder 









































???
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3cu2 chain A

3D model

Region: 1 - 219
Aligned: 215
Modelled: 219
Confidence: 100.0%
Identity: 26%
PDB header:isomerase
Chain: A: PDB Molecule:ribulose-5-phosphate 3-epimerase;
PDBTitle: crystal structure of ribulose-5-phosphate 3-epimerase (yp_718263.1)2 from haemophilus somnus 129pt at 1.91 a resolution

Phyre2

PDB 3ct7 chain E

3D model

Region: 5 - 220
Aligned: 214
Modelled: 216
Confidence: 100.0%
Identity: 36%
PDB header:isomerase
Chain: E: PDB Molecule:d-allulose-6-phosphate 3-epimerase;
PDBTitle: crystal structure of d-allulose 6-phosphate 3-epimerase2 from escherichia coli k-12

Phyre2

PDB 3qc3 chain B

3D model

Region: 2 - 224
Aligned: 219
Modelled: 223
Confidence: 100.0%
Identity: 38%
PDB header:isomerase
Chain: B: PDB Molecule:d-ribulose-5-phosphate-3-epimerase;
PDBTitle: crystal structure of a d-ribulose-5-phosphate-3-epimerase (np_954699)2 from homo sapiens at 2.20 a resolution

Phyre2

PDB 3inp chain A

3D model

Region: 3 - 221
Aligned: 217
Modelled: 219
Confidence: 100.0%
Identity: 63%
PDB header:isomerase
Chain: A: PDB Molecule:d-ribulose-phosphate 3-epimerase;
PDBTitle: 2.05 angstrom resolution crystal structure of d-ribulose-phosphate 3-2 epimerase from francisella tularensis.

Phyre2

PDB 1rpx chain A

3D model

Region: 2 - 217
Aligned: 215
Modelled: 216
Confidence: 100.0%
Identity: 47%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: D-ribulose-5-phosphate 3-epimerase

Phyre2

PDB 1tqx chain A

3D model

Region: 1 - 221
Aligned: 216
Modelled: 221
Confidence: 100.0%
Identity: 36%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: D-ribulose-5-phosphate 3-epimerase

Phyre2

PDB 2fli chain A domain 1

3D model

Region: 5 - 219
Aligned: 214
Modelled: 215
Confidence: 100.0%
Identity: 44%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: D-ribulose-5-phosphate 3-epimerase

Phyre2

PDB 1h1y chain A

3D model

Region: 5 - 222
Aligned: 213
Modelled: 218
Confidence: 100.0%
Identity: 41%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: D-ribulose-5-phosphate 3-epimerase

Phyre2

PDB 1tqj chain A

3D model

Region: 2 - 217
Aligned: 211
Modelled: 216
Confidence: 100.0%
Identity: 51%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: D-ribulose-5-phosphate 3-epimerase

Phyre2

PDB 1q6o chain A

3D model

Region: 7 - 221
Aligned: 204
Modelled: 215
Confidence: 99.9%
Identity: 13%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Decarboxylase

Phyre2

PDB 3ajx chain A

3D model

Region: 1 - 220
Aligned: 205
Modelled: 215
Confidence: 99.9%
Identity: 19%
PDB header:lyase
Chain: A: PDB Molecule:3-hexulose-6-phosphate synthase;
PDBTitle: crystal structure of 3-hexulose-6-phosphate synthase

Phyre2

PDB 3f4w chain A

3D model

Region: 1 - 221
Aligned: 205
Modelled: 208
Confidence: 99.9%
Identity: 18%
PDB header:synthase, lyase
Chain: A: PDB Molecule:putative hexulose 6 phosphate synthase;
PDBTitle: the 1.65a crystal structure of 3-hexulose-6-phosphate2 synthase from salmonella typhimurium

Phyre2

PDB 1qop chain A

3D model

Region: 2 - 224
Aligned: 215
Modelled: 223
Confidence: 99.9%
Identity: 18%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Tryptophan biosynthesis enzymes

Phyre2

PDB 3jr2 chain D

3D model

Region: 2 - 222
Aligned: 207
Modelled: 214
Confidence: 99.9%
Identity: 17%
PDB header:biosynthetic protein
Chain: D: PDB Molecule:hexulose-6-phosphate synthase sgbh;
PDBTitle: x-ray crystal structure of the mg-bound 3-keto-l-gulonate-6-phosphate2 decarboxylase from vibrio cholerae o1 biovar el tor str. n16961

Phyre2

PDB 3exs chain B

3D model

Region: 8 - 224
Aligned: 204
Modelled: 209
Confidence: 99.9%
Identity: 17%
PDB header:lyase
Chain: B: PDB Molecule:rmpd (hexulose-6-phosphate synthase);
PDBTitle: crystal structure of kgpdc from streptococcus mutans in2 complex with d-r5p

Phyre2

PDB 1eix chain A

3D model

Region: 1 - 220
Aligned: 214
Modelled: 213
Confidence: 99.9%
Identity: 13%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Decarboxylase

Phyre2

PDB 2ekc chain A

3D model

Region: 2 - 225
Aligned: 210
Modelled: 214
Confidence: 99.9%
Identity: 16%
PDB header:lyase
Chain: A: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5

Phyre2

PDB 3tha chain B

3D model

Region: 2 - 220
Aligned: 213
Modelled: 215
Confidence: 99.9%
Identity: 12%
PDB header:lyase
Chain: B: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: tryptophan synthase subunit alpha from campylobacter jejuni.

Phyre2

PDB 1rd5 chain A

3D model

Region: 2 - 223
Aligned: 216
Modelled: 222
Confidence: 99.9%
Identity: 18%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Tryptophan biosynthesis enzymes

Phyre2

PDB 3nav chain B

3D model

Region: 2 - 224
Aligned: 207
Modelled: 210
Confidence: 99.9%
Identity: 16%
PDB header:lyase
Chain: B: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: crystal structure of an alpha subunit of tryptophan synthase from2 vibrio cholerae o1 biovar el tor str. n16961

Phyre2
1

c3cu2A_
2

c3ct7E_
3

c3qc3B_
4

c3inpA_
5

d1rpxa_
6

d1tqxa_
7

d2flia1
8

d1h1ya_
9

d1tqja_
10

d1q6oa_
11

c3ajxA_
12

c3f4wA_
13

d1qopa_
14

c3jr2D_
15

c3exsB_
16

d1eixa_
17

c2ekcA_
18

c3thaB_
19

d1rd5a_
20

c3navB_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3cu2A_



100.0 26 PDB header:isomerase
Chain: A: PDB Molecule:ribulose-5-phosphate 3-epimerase;
PDBTitle: crystal structure of ribulose-5-phosphate 3-epimerase (yp_718263.1)2 from haemophilus somnus 129pt at 1.91 a resolution
2c3ct7E_



100.0 36 PDB header:isomerase
Chain: E: PDB Molecule:d-allulose-6-phosphate 3-epimerase;
PDBTitle: crystal structure of d-allulose 6-phosphate 3-epimerase2 from escherichia coli k-12
3c3qc3B_



100.0 38 PDB header:isomerase
Chain: B: PDB Molecule:d-ribulose-5-phosphate-3-epimerase;
PDBTitle: crystal structure of a d-ribulose-5-phosphate-3-epimerase (np_954699)2 from homo sapiens at 2.20 a resolution
4c3inpA_



100.0 63 PDB header:isomerase
Chain: A: PDB Molecule:d-ribulose-phosphate 3-epimerase;
PDBTitle: 2.05 angstrom resolution crystal structure of d-ribulose-phosphate 3-2 epimerase from francisella tularensis.
5d1rpxa_



100.0 47 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
6d1tqxa_



100.0 36 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
7d2flia1



100.0 44 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
8d1h1ya_



100.0 41 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
9d1tqja_



100.0 51 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
10d1q6oa_



99.9 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
11c3ajxA_



99.9 19 PDB header:lyase
Chain: A: PDB Molecule:3-hexulose-6-phosphate synthase;
PDBTitle: crystal structure of 3-hexulose-6-phosphate synthase
12c3f4wA_



99.9 18 PDB header:synthase, lyase
Chain: A: PDB Molecule:putative hexulose 6 phosphate synthase;
PDBTitle: the 1.65a crystal structure of 3-hexulose-6-phosphate2 synthase from salmonella typhimurium
13d1qopa_



99.9 18 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
14c3jr2D_



99.9 17 PDB header:biosynthetic protein
Chain: D: PDB Molecule:hexulose-6-phosphate synthase sgbh;
PDBTitle: x-ray crystal structure of the mg-bound 3-keto-l-gulonate-6-phosphate2 decarboxylase from vibrio cholerae o1 biovar el tor str. n16961
15c3exsB_



99.9 17 PDB header:lyase
Chain: B: PDB Molecule:rmpd (hexulose-6-phosphate synthase);
PDBTitle: crystal structure of kgpdc from streptococcus mutans in2 complex with d-r5p
16d1eixa_



99.9 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
17c2ekcA_



99.9 16 PDB header:lyase
Chain: A: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5
18c3thaB_



99.9 12 PDB header:lyase
Chain: B: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: tryptophan synthase subunit alpha from campylobacter jejuni.
19d1rd5a_



99.9 18 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
20c3navB_



99.9 16 PDB header:lyase
Chain: B: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: crystal structure of an alpha subunit of tryptophan synthase from2 vibrio cholerae o1 biovar el tor str. n16961
21d1km4a_



not modelled 99.9 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
22c3ru6C_



not modelled 99.9 12 PDB header:lyase
Chain: C: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: 1.8 angstrom resolution crystal structure of orotidine 5'-phosphate2 decarboxylase (pyrf) from campylobacter jejuni subsp. jejuni nctc3 11168
23d2czda1



not modelled 99.9 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
24c3nm3D_



not modelled 99.9 16 PDB header:transferase
Chain: D: PDB Molecule:thiamine biosynthetic bifunctional enzyme;
PDBTitle: the crystal structure of candida glabrata thi6, a bifunctional enzyme2 involved in thiamin biosyhthesis of eukaryotes
25c3tfxB_



not modelled 99.9 16 PDB header:lyase
Chain: B: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: crystal structure of orotidine 5'-phosphate decarboxylase from2 lactobacillus acidophilus
26d1xcfa_



not modelled 99.9 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
27c3ldvB_



not modelled 99.9 15 PDB header:lyase
Chain: B: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: 1.77 angstrom resolution crystal structure of orotidine 5'-2 phosphate decarboxylase from vibrio cholerae o1 biovar3 eltor str. n16961
28d1dvja_



not modelled 99.9 17 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
29c3tr2A_



not modelled 99.9 15 PDB header:lyase
Chain: A: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: structure of a orotidine 5'-phosphate decarboxylase (pyrf) from2 coxiella burnetii
30d1vqta1



not modelled 99.9 18 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
31d1dbta_



not modelled 99.9 21 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
32d1geqa_



not modelled 99.9 17 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
33c2yytA_



not modelled 99.9 16 PDB header:lyase
Chain: A: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: crystal structure of uncharacterized conserved protein from2 geobacillus kaustophilus
34d1ujpa_



not modelled 99.9 19 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
35d2tpsa_



not modelled 99.8 21 Fold:TIM beta/alpha-barrel
Superfamily:Thiamin phosphate synthase
Family:Thiamin phosphate synthase
36d1wbha1



not modelled 99.8 13 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
37d1xi3a_



not modelled 99.8 23 Fold:TIM beta/alpha-barrel
Superfamily:Thiamin phosphate synthase
Family:Thiamin phosphate synthase
38c1yadD_



not modelled 99.8 15 PDB header:transcription
Chain: D: PDB Molecule:regulatory protein teni;
PDBTitle: structure of teni from bacillus subtilis
39d1vc4a_



not modelled 99.8 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
40c2v82A_



not modelled 99.8 13 PDB header:lyase
Chain: A: PDB Molecule:2-dehydro-3-deoxy-6-phosphogalactonate aldolase;
PDBTitle: kdpgal complexed to kdpgal
41d1wa3a1



not modelled 99.8 17 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
42c3qjaA_



not modelled 99.8 15 PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of the mycobacterium tuberculosis indole-3-glycerol2 phosphate synthase (trpc) in apo form
43c3o63B_



not modelled 99.8 19 PDB header:transferase
Chain: B: PDB Molecule:probable thiamine-phosphate pyrophosphorylase;
PDBTitle: crystal structure of thiamin phosphate synthase from mycobacterium2 tuberculosis
44d1j5ta_



not modelled 99.8 17 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
45d1vhca_



not modelled 99.8 13 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
46c2bdqA_



not modelled 99.8 14 PDB header:metal transport
Chain: A: PDB Molecule:copper homeostasis protein cutc;
PDBTitle: crystal structure of the putative copper homeostasis2 protein cutc from streptococcus agalactiae, northeast3 strucural genomics target sar15.
47d1i4na_



not modelled 99.8 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
48d1a53a_



not modelled 99.8 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
49c2y85D_



not modelled 99.8 15 PDB header:isomerase
Chain: D: PDB Molecule:phosphoribosyl isomerase a;
PDBTitle: crystal structure of mycobacterium tuberculosis phosphoribosyl2 isomerase with bound rcdrp
50c2c3zA_



not modelled 99.8 15 PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus
51d1piia2



not modelled 99.8 10 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
52d1mxsa_



not modelled 99.8 16 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
53d1ka9f_



not modelled 99.8 19 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
54c3labA_



not modelled 99.7 13 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative kdpg (2-keto-3-deoxy-6-phosphogluconate)
PDBTitle: crystal structure of a putative kdpg (2-keto-3-deoxy-6-2 phosphogluconate) aldolase from oleispira antarctica
55d1thfd_



not modelled 99.7 19 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
56c3igsB_



not modelled 99.7 22 PDB header:isomerase
Chain: B: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase 2;
PDBTitle: structure of the salmonella enterica n-acetylmannosamine-6-phosphate2 2-epimerase
57c3ceuA_



not modelled 99.7 12 PDB header:transferase
Chain: A: PDB Molecule:thiamine phosphate pyrophosphorylase;
PDBTitle: crystal structure of thiamine phosphate pyrophosphorylase2 (bt_0647) from bacteroides thetaiotaomicron. northeast3 structural genomics consortium target btr268
58d1yxya1



not modelled 99.7 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:NanE-like
59d1y0ea_



not modelled 99.7 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:NanE-like
60d1h5ya_



not modelled 99.7 20 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
61c2yw3E_



not modelled 99.7 16 PDB header:lyase
Chain: E: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase/2-deydro-3-
PDBTitle: crystal structure analysis of the 4-hydroxy-2-oxoglutarate aldolase/2-2 deydro-3-deoxyphosphogluconate aldolase from tthb1
62c1piiA_



not modelled 99.7 11 PDB header:bifunctional(isomerase and synthase)
Chain: A: PDB Molecule:n-(5'phosphoribosyl)anthranilate isomerase;
PDBTitle: three-dimensional structure of the bifunctional enzyme2 phosphoribosylanthranilate isomerase:3 indoleglycerolphosphate synthase from escherichia coli4 refined at 2.0 angstroms resolution
63d1dqwa_



not modelled 99.7 17 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
64d1losc_



not modelled 99.7 18 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
65c3q58A_



not modelled 99.7 19 PDB header:isomerase
Chain: A: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase;
PDBTitle: structure of n-acetylmannosamine-6-phosphate epimerase from salmonella2 enterica
66c2qcnA_



not modelled 99.6 18 PDB header:lyase
Chain: A: PDB Molecule:uridine 5'-monophosphate synthase;
PDBTitle: covalent complex of the orotidine-5'-monophosphate decarboxylase2 domain of human ump synthase with 6-iodo-ump
67c3bvjA_



not modelled 99.6 18 PDB header:lyase
Chain: A: PDB Molecule:uridine 5'-monophosphate synthase;
PDBTitle: crystal structure of human orotidine 5'-monophosphate decarboxylase2 complexed with xmp
68d1vzwa1



not modelled 99.6 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
69d1w0ma_



not modelled 99.6 15 Fold:TIM beta/alpha-barrel
Superfamily:Triosephosphate isomerase (TIM)
Family:Triosephosphate isomerase (TIM)
70d1hg3a_



not modelled 99.6 12 Fold:TIM beta/alpha-barrel
Superfamily:Triosephosphate isomerase (TIM)
Family:Triosephosphate isomerase (TIM)
71d1ojxa_



not modelled 99.5 13 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
72c1znnF_



not modelled 99.5 15 PDB header:biosynthetic protein
Chain: F: PDB Molecule:plp synthase;
PDBTitle: structure of the synthase subunit of plp synthase
73d1znna1



not modelled 99.5 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:PdxS-like
74d1jvna1



not modelled 99.4 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
75c3qw3B_



not modelled 99.4 16 PDB header:transferase, lyase
Chain: B: PDB Molecule:orotidine-5-phosphate decarboxylase/orotate
PDBTitle: structure of leishmania donovani omp decarboxylase
76c2w6rA_



not modelled 99.4 19 PDB header:lyase
Chain: A: PDB Molecule:imidazole glycerol phosphate synthase subunit
PDBTitle: crystal structure of an artificial (ba)8-barrel protein2 designed from identical half barrels
77c3gndC_



not modelled 99.4 12 PDB header:lyase
Chain: C: PDB Molecule:aldolase lsrf;
PDBTitle: crystal structure of e. coli lsrf in complex with ribulose-5-phosphate
78d1qo2a_



not modelled 99.3 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
79c1jvnB_



not modelled 99.3 16 PDB header:transferase
Chain: B: PDB Molecule:bifunctional histidine biosynthesis protein hishf;
PDBTitle: crystal structure of imidazole glycerol phosphate synthase: a tunnel2 through a (beta/alpha)8 barrel joins two active sites
80c2qjhH_



not modelled 99.3 14 PDB header:lyase
Chain: H: PDB Molecule:putative aldolase mj0400;
PDBTitle: m. jannaschii adh synthase covalently bound to2 dihydroxyacetone phosphate
81d1wv2a_



not modelled 99.3 15 Fold:TIM beta/alpha-barrel
Superfamily:ThiG-like
Family:ThiG-like
82d1viza_



not modelled 99.3 12 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
83d2q8za1



not modelled 99.2 12 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
84d2ffca1



not modelled 99.2 12 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
85c2h6rG_



not modelled 99.2 14 PDB header:isomerase
Chain: G: PDB Molecule:triosephosphate isomerase;
PDBTitle: crystal structure of triosephosphate isomerase (tim) from2 methanocaldococcus jannaschii
86c2fdsA_



not modelled 99.2 12 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:orotidine-monophosphate-decarboxylase;
PDBTitle: crystal structure of plasmodium berghei orotidine 5'-2 monophosphate decarboxylase (ortholog of plasmodium3 falciparum pf10_0225)
87d2fdsa1



not modelled 99.2 12 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
88d1o4ua1



not modelled 99.1 16 Fold:TIM beta/alpha-barrel
Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like
Family:NadC C-terminal domain-like
89c2agkA_



not modelled 99.1 10 PDB header:isomerase
Chain: A: PDB Molecule:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)
PDBTitle: structure of s. cerevisiae his6 protein
90c2htmB_



not modelled 99.0 17 PDB header:biosynthetic protein
Chain: B: PDB Molecule:thiazole biosynthesis protein thig;
PDBTitle: crystal structure of ttha0676 from thermus thermophilus hb8
91d2f6ua1



not modelled 99.0 10 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
92d1xm3a_



not modelled 99.0 13 Fold:TIM beta/alpha-barrel
Superfamily:ThiG-like
Family:ThiG-like
93c3qw4B_



not modelled 98.9 13 PDB header:transferase, lyase
Chain: B: PDB Molecule:ump synthase;
PDBTitle: structure of leishmania donovani ump synthase
94d1qpoa1



not modelled 98.8 17 Fold:TIM beta/alpha-barrel
Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like
Family:NadC C-terminal domain-like
95d1eepa_



not modelled 98.7 16 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
96c2gjlA_



not modelled 98.7 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:hypothetical protein pa1024;
PDBTitle: crystal structure of 2-nitropropane dioxygenase
97d1qapa1



not modelled 98.7 22 Fold:TIM beta/alpha-barrel
Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like
Family:NadC C-terminal domain-like
98d1twda_



not modelled 98.6 17 Fold:TIM beta/alpha-barrel
Superfamily:CutC-like
Family:CutC-like
99c3r89A_



not modelled 98.6 15 PDB header:lyase
Chain: A: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: crystal structure of orotidine 5-phosphate decarboxylase from2 anaerococcus prevotii dsm 20548
100c1zfjA_



not modelled 98.6 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine monophosphate dehydrogenase;
PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes
101c2b7pA_



not modelled 98.6 16 PDB header:transferase
Chain: A: PDB Molecule:probable nicotinate-nucleotide pyrophosphorylase;
PDBTitle: crystal structure of quinolinic acid phosphoribosyltransferase from2 helicobacter pylori
102c2cdh1_



not modelled 98.6 23 PDB header:transferase
Chain: 1: PDB Molecule:enoyl reductase;
PDBTitle: architecture of the thermomyces lanuginosus fungal fatty2 acid synthase at 5 angstrom resolution.
103d1gtea2



not modelled 98.6 18 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
104c1o4uA_



not modelled 98.6 15 PDB header:transferase
Chain: A: PDB Molecule:type ii quinolic acid phosphoribosyltransferase;
PDBTitle: crystal structure of a nicotinate nucleotide pyrophosphorylase2 (tm1645) from thermotoga maritima at 2.50 a resolution
105c1vrdA_



not modelled 98.6 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine-5'-monophosphate dehydrogenase;
PDBTitle: crystal structure of inosine-5'-monophosphate dehydrogenase (tm1347)2 from thermotoga maritima at 2.18 a resolution
106c3khjE_



not modelled 98.6 19 PDB header:oxidoreductase
Chain: E: PDB Molecule:inosine-5-monophosphate dehydrogenase;
PDBTitle: c. parvum inosine monophosphate dehydrogenase bound by inhibitor c64
107d1tb3a1



not modelled 98.5 23 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
108d1jcna1



not modelled 98.5 14 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
109d1jr1a1



not modelled 98.5 17 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
110c1qpoA_



not modelled 98.5 17 PDB header:transferase
Chain: A: PDB Molecule:quinolinate acid phosphoribosyl transferase;
PDBTitle: quinolinate phosphoribosyl transferase (qaprtase) apo-enzyme from2 mycobacterium tuberculosis
111c2nv2U_



not modelled 98.5 16 PDB header:lyase/transferase
Chain: U: PDB Molecule:pyridoxal biosynthesis lyase pdxs;
PDBTitle: structure of the plp synthase complex pdx1/2 (yaad/e) from bacillus2 subtilis
112c2zbtB_



not modelled 98.5 14 PDB header:lyase
Chain: B: PDB Molecule:pyridoxal biosynthesis lyase pdxs;
PDBTitle: crystal structure of pyridoxine biosynthesis protein from thermus2 thermophilus hb8
113c3ffsC_



not modelled 98.5 20 PDB header:oxidoreductase
Chain: C: PDB Molecule:inosine-5-monophosphate dehydrogenase;
PDBTitle: the crystal structure of cryptosporidium parvum inosine-5'-2 monophosphate dehydrogenase
114c2jbmA_



not modelled 98.5 13 PDB header:transferase
Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase;
PDBTitle: qprtase structure from human
115c3iwpK_



not modelled 98.5 14 PDB header:metal binding protein
Chain: K: PDB Molecule:copper homeostasis protein cutc homolog;
PDBTitle: crystal structure of human copper homeostasis protein cutc
116c2z6jB_



not modelled 98.5 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:trans-2-enoyl-acp reductase ii;
PDBTitle: crystal structure of s. pneumoniae enoyl-acyl carrier2 protein reductase (fabk) in complex with an inhibitor
117d1nsja_



not modelled 98.5 18 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
118d1kbia1



not modelled 98.5 20 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
119d1vrda1



not modelled 98.4 19 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
120c1x1oC_



not modelled 98.4 21 PDB header:transferase
Chain: C: PDB Molecule:nicotinate-nucleotide pyrophosphorylase;
PDBTitle: crystal structure of project id tt0268 from thermus thermophilus hb8

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0