Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP05804
DateThu Jan 5 10:58:55 GMT 2012
Unique Job ID69acfa2e424687b1

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3lpgA_
Top template information
PDB header:hydrolase/hydrolase inhibitor
Chain: A: PDB Molecule:beta-glucuronidase;
PDBTitle: structure of e. coli beta-glucuronidase bound with a novel, potent2 inhibitor 3-(2-fluorophenyl)-1-(2-hydroxyethyl)-1-((6-methyl-2-oxo-1,3 2-dihydroquinolin-3-yl)methyl)urea
Confidence and coverage
Confidence:100.0% Coverage:100%
600 residues (100% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MLRPVETPTREIKKLDGLWAFSLDRENCGIDQRWWESALQESRAIAVPGSFNDQFADADI
Secondary structure 
SS confidence 
Disorder  ????????
??????
?
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  RNYAGNVWYQREVFIPKGWAGQRIVLRFDAVTHYGKVWVNNQEVMEHQGGYTPFEADVTP
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  YVIAGKSVRITVCVNNELNWQTIPPGMVITDENGKKKQSYFHDFFNYAGIHRSVMLYTTP
Secondary structure 
SS confidence 
Disorder 
??
?
?
???????
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  NTWVDDITVVTHVAQDCNHASVDWQVVANGDVSVELRDADQQVVATGQGTSGTLQVVNPH
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  LWQPGEGYLYELCVTAKSQTECDIYPLRVGIRSVAVKGEQFLINHKPFYFTGFGRHEDAD
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  LRGKGFDNVLMVHDHALMDWIGANSYRTSHYPYAEEMLDWADEHGIVVIDETAAVGFNLS
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  LGIGFEAGNKPKELYSEEAVNGETQQAHLQAIKELIARDKNHPSVVMWSIANEPDTRPQG
Secondary structure 
SS confidence 
Disorder 
?
???
??
?
?
?
Disorder confidence 
 
   .........430.........440.........450.........460.........470.........480
Sequence  AREYFAPLAEATRKLDPTRPITCVNVMFCDAHTDTISDLFDVLCLNRYYGWYVQSGDLET
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........490.........500.........510.........520.........530.........540
Sequence  AEKVLEKELLAWQEKLHQPIIITEYGVDTLAGLHSMYTDMWSEEYQCAWLDMYHRVFDRV
Secondary structure 
SS confidence 
Disorder 
??
??
Disorder confidence 
 
   .........550.........560.........570.........580.........590.........600
Sequence  SAVVGEQVWNFADFATSQGILRVGGNKKGIFTRDRKPKSAAFLLQKRWTGMNFGEKPQQG
Secondary structure 
SS confidence 
Disorder 
???
Disorder confidence 
 
   ...
Sequence  GKQ
Secondary structure 
SS confidence 
Disorder  ???
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3lpg chain A

3D model

Region: 2 - 601
Aligned: 600
Modelled: 600
Confidence: 100.0%
Identity: 98%
PDB header:hydrolase/hydrolase inhibitor
Chain: A: PDB Molecule:beta-glucuronidase;
PDBTitle: structure of e. coli beta-glucuronidase bound with a novel, potent2 inhibitor 3-(2-fluorophenyl)-1-(2-hydroxyethyl)-1-((6-methyl-2-oxo-1,3 2-dihydroquinolin-3-yl)methyl)urea

Phyre2

PDB 1bhg chain B

3D model

Region: 1 - 591
Aligned: 572
Modelled: 574
Confidence: 100.0%
Identity: 48%
PDB header:glycosidase
Chain: B: PDB Molecule:beta-glucuronidase;
PDBTitle: human beta-glucuronidase at 2.6 a resolution

Phyre2

PDB 3fn9 chain B

3D model

Region: 8 - 590
Aligned: 539
Modelled: 542
Confidence: 100.0%
Identity: 24%
PDB header:hydrolase
Chain: B: PDB Molecule:putative beta-galactosidase;
PDBTitle: crystal structure of putative beta-galactosidase from bacteroides2 fragilis

Phyre2

PDB 3cmg chain A

3D model

Region: 10 - 590
Aligned: 532
Modelled: 552
Confidence: 100.0%
Identity: 28%
PDB header:hydrolase
Chain: A: PDB Molecule:putative beta-galactosidase;
PDBTitle: crystal structure of putative beta-galactosidase from bacteroides2 fragilis

Phyre2

PDB 3mv1 chain 4

3D model

Region: 7 - 593
Aligned: 528
Modelled: 528
Confidence: 100.0%
Identity: 26%
PDB header:hydrolase
Chain: 4: PDB Molecule:beta-galactosidase;
PDBTitle: e.coli (lacz) beta-galactosidase (r599a) in complex with guanidinium

Phyre2

PDB 1jz6 chain C

3D model

Region: 7 - 593
Aligned: 528
Modelled: 528
Confidence: 100.0%
Identity: 26%
PDB header:hydrolase
Chain: C: PDB Molecule:beta-galactosidase;
PDBTitle: e. coli (lacz) beta-galactosidase in complex with galacto-2 tetrazole

Phyre2

PDB 3oba chain A

3D model

Region: 4 - 593
Aligned: 537
Modelled: 567
Confidence: 100.0%
Identity: 23%
PDB header:hydrolase
Chain: A: PDB Molecule:beta-galactosidase;
PDBTitle: structure of the beta-galactosidase from kluyveromyces lactis

Phyre2

PDB 3gm8 chain A

3D model

Region: 11 - 590
Aligned: 516
Modelled: 542
Confidence: 100.0%
Identity: 23%
PDB header:hydrolase
Chain: A: PDB Molecule:glycoside hydrolase family 2, candidate beta-glycosidase;
PDBTitle: crystal structure of a beta-glycosidase from bacteroides vulgatus

Phyre2

PDB 3bga chain B

3D model

Region: 7 - 602
Aligned: 525
Modelled: 554
Confidence: 100.0%
Identity: 23%
PDB header:hydrolase
Chain: B: PDB Molecule:beta-galactosidase;
PDBTitle: crystal structure of beta-galactosidase from bacteroides2 thetaiotaomicron vpi-5482

Phyre2

PDB 1yq2 chain C

3D model

Region: 3 - 603
Aligned: 543
Modelled: 577
Confidence: 100.0%
Identity: 26%
PDB header:hydrolase
Chain: C: PDB Molecule:beta-galactosidase;
PDBTitle: beta-galactosidase from arthrobacter sp. c2-2 (isoenzyme c2-2 2-1)

Phyre2

PDB 2je8 chain B

3D model

Region: 9 - 601
Aligned: 534
Modelled: 535
Confidence: 100.0%
Identity: 18%
PDB header:hydrolase
Chain: B: PDB Molecule:beta-mannosidase;
PDBTitle: structure of a beta-mannosidase from bacteroides2 thetaiotaomicron

Phyre2

PDB 2vzv chain B

3D model

Region: 5 - 601
Aligned: 538
Modelled: 551
Confidence: 100.0%
Identity: 17%
PDB header:hydrolase
Chain: B: PDB Molecule:exo-beta-d-glucosaminidase;
PDBTitle: substrate complex of amycolatopsis orientalis exo-2 chitosanase csxa e541a with chitosan

Phyre2

PDB 1bhg chain A domain 3

3D model

Region: 274 - 591
Aligned: 299
Modelled: 301
Confidence: 100.0%
Identity: 51%
Fold: TIM beta/alpha-barrel
Superfamily: (Trans)glycosidases
Family: beta-glycanases

Phyre2

PDB 1yq2 chain A domain 5

3D model

Region: 274 - 589
Aligned: 279
Modelled: 294
Confidence: 100.0%
Identity: 29%
Fold: TIM beta/alpha-barrel
Superfamily: (Trans)glycosidases
Family: beta-glycanases

Phyre2

PDB 1jz8 chain A domain 5

3D model

Region: 273 - 589
Aligned: 275
Modelled: 301
Confidence: 100.0%
Identity: 25%
Fold: TIM beta/alpha-barrel
Superfamily: (Trans)glycosidases
Family: beta-glycanases

Phyre2

PDB 2je8 chain A domain 5

3D model

Region: 272 - 590
Aligned: 274
Modelled: 275
Confidence: 100.0%
Identity: 18%
Fold: TIM beta/alpha-barrel
Superfamily: (Trans)glycosidases
Family: beta-glycanases

Phyre2

PDB 2vzs chain A domain 5

3D model

Region: 278 - 587
Aligned: 271
Modelled: 288
Confidence: 100.0%
Identity: 17%
Fold: TIM beta/alpha-barrel
Superfamily: (Trans)glycosidases
Family: beta-glycanases

Phyre2

PDB 1bhg chain A domain 2

3D model

Region: 1 - 181
Aligned: 181
Modelled: 181
Confidence: 100.0%
Identity: 46%
Fold: Galactose-binding domain-like
Superfamily: Galactose-binding domain-like
Family: beta-Galactosidase/glucuronidase, N-terminal domain

Phyre2

PDB 1uuq chain A

3D model

Region: 274 - 590
Aligned: 317
Modelled: 317
Confidence: 100.0%
Identity: 15%
Fold: TIM beta/alpha-barrel
Superfamily: (Trans)glycosidases
Family: beta-glycanases

Phyre2

PDB 1uz4 chain A

3D model

Region: 274 - 590
Aligned: 317
Modelled: 317
Confidence: 100.0%
Identity: 15%
PDB header:hydrolase
Chain: A: PDB Molecule:man5a;
PDBTitle: common inhibition of beta-glucosidase and beta-mannosidase2 by isofagomine lactam reflects different conformational3 intineraries for glucoside and mannoside hydrolysis

Phyre2
1
c3lpgA_
2
c1bhgB_
3
c3fn9B_
4
c3cmgA_
5
c3mv14_
6
c1jz6C_
7
c3obaA_
8
c3gm8A_
9
c3bgaB_
10
c1yq2C_
11
c2je8B_
12
c2vzvB_
13
d1bhga3
14
d1yq2a5
15
d1jz8a5
16
d2je8a5
17
d2vzsa5
18
d1bhga2
19
d1uuqa_
20
c1uz4A_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3lpgA_
100.0 98 PDB header:hydrolase/hydrolase inhibitor
Chain: A: PDB Molecule:beta-glucuronidase;
PDBTitle: structure of e. coli beta-glucuronidase bound with a novel, potent2 inhibitor 3-(2-fluorophenyl)-1-(2-hydroxyethyl)-1-((6-methyl-2-oxo-1,3 2-dihydroquinolin-3-yl)methyl)urea
2c1bhgB_
100.0 48 PDB header:glycosidase
Chain: B: PDB Molecule:beta-glucuronidase;
PDBTitle: human beta-glucuronidase at 2.6 a resolution
3c3fn9B_
100.0 24 PDB header:hydrolase
Chain: B: PDB Molecule:putative beta-galactosidase;
PDBTitle: crystal structure of putative beta-galactosidase from bacteroides2 fragilis
4c3cmgA_
100.0 28 PDB header:hydrolase
Chain: A: PDB Molecule:putative beta-galactosidase;
PDBTitle: crystal structure of putative beta-galactosidase from bacteroides2 fragilis
5c3mv14_
100.0 26 PDB header:hydrolase
Chain: 4: PDB Molecule:beta-galactosidase;
PDBTitle: e.coli (lacz) beta-galactosidase (r599a) in complex with guanidinium
6c1jz6C_
100.0 26 PDB header:hydrolase
Chain: C: PDB Molecule:beta-galactosidase;
PDBTitle: e. coli (lacz) beta-galactosidase in complex with galacto-2 tetrazole
7c3obaA_
100.0 23 PDB header:hydrolase
Chain: A: PDB Molecule:beta-galactosidase;
PDBTitle: structure of the beta-galactosidase from kluyveromyces lactis
8c3gm8A_
100.0 23 PDB header:hydrolase
Chain: A: PDB Molecule:glycoside hydrolase family 2, candidate beta-glycosidase;
PDBTitle: crystal structure of a beta-glycosidase from bacteroides vulgatus
9c3bgaB_
100.0 23 PDB header:hydrolase
Chain: B: PDB Molecule:beta-galactosidase;
PDBTitle: crystal structure of beta-galactosidase from bacteroides2 thetaiotaomicron vpi-5482
10c1yq2C_
100.0 26 PDB header:hydrolase
Chain: C: PDB Molecule:beta-galactosidase;
PDBTitle: beta-galactosidase from arthrobacter sp. c2-2 (isoenzyme c2-2 2-1)
11c2je8B_
100.0 18 PDB header:hydrolase
Chain: B: PDB Molecule:beta-mannosidase;
PDBTitle: structure of a beta-mannosidase from bacteroides2 thetaiotaomicron
12c2vzvB_
100.0 17 PDB header:hydrolase
Chain: B: PDB Molecule:exo-beta-d-glucosaminidase;
PDBTitle: substrate complex of amycolatopsis orientalis exo-2 chitosanase csxa e541a with chitosan
13d1bhga3
100.0 51 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
14d1yq2a5
100.0 29 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
15d1jz8a5
100.0 25 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
16d2je8a5
100.0 18 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
17d2vzsa5
100.0 17 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
18d1bhga2
100.0 46 Fold:Galactose-binding domain-like
Superfamily:Galactose-binding domain-like
Family:beta-Galactosidase/glucuronidase, N-terminal domain
19d1uuqa_
100.0 15 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
20c1uz4A_
100.0 15 PDB header:hydrolase
Chain: A: PDB Molecule:man5a;
PDBTitle: common inhibition of beta-glucosidase and beta-mannosidase2 by isofagomine lactam reflects different conformational3 intineraries for glucoside and mannoside hydrolysis
21c2w62A_
not modelled 100.0 13 PDB header:transferase
Chain: A: PDB Molecule:glycolipid-anchored surface protein 2;
PDBTitle: saccharomyces cerevisiae gas2p in complex with2 laminaripentaose
22d1jz8a3
not modelled 100.0 24 Fold:Galactose-binding domain-like
Superfamily:Galactose-binding domain-like
Family:beta-Galactosidase/glucuronidase, N-terminal domain
23d1tg7a5
not modelled 100.0 12 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Glycosyl hydrolases family 35 catalytic domain
24d1yq2a3
not modelled 100.0 25 Fold:Galactose-binding domain-like
Superfamily:Galactose-binding domain-like
Family:beta-Galactosidase/glucuronidase, N-terminal domain
25d1rh9a1
not modelled 100.0 15 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
26d2c0ha1
not modelled 100.0 18 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
27d2je8a4
not modelled 100.0 19 Fold:Galactose-binding domain-like
Superfamily:Galactose-binding domain-like
Family:beta-Galactosidase/glucuronidase, N-terminal domain
28d1qnra_
not modelled 100.0 14 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
29c3civA_
not modelled 99.9 12 PDB header:hydrolase
Chain: A: PDB Molecule:endo-beta-1,4-mannanase;
PDBTitle: crystal structure of the endo-beta-1,4-mannanase from2 alicyclobacillus acidocaldarius
30d1wkya2
not modelled 99.9 17 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
31d7a3ha_
not modelled 99.9 16 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
32c3jugA_
not modelled 99.9 15 PDB header:hydrolase
Chain: A: PDB Molecule:beta-mannanase;
PDBTitle: crystal structure of endo-beta-1,4-mannanase from the alkaliphilic2 bacillus sp. n16-5
33d1egza_
not modelled 99.9 17 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
34d2vzsa4
not modelled 99.9 18 Fold:Galactose-binding domain-like
Superfamily:Galactose-binding domain-like
Family:beta-Galactosidase/glucuronidase, N-terminal domain
35c3pzvB_
not modelled 99.9 21 PDB header:hydrolase
Chain: B: PDB Molecule:endoglucanase;
PDBTitle: c2 crystal form of the endo-1,4-beta-glucanase from bacillus subtilis2 168
36c3thdD_
not modelled 99.9 15 PDB header:hydrolase
Chain: D: PDB Molecule:beta-galactosidase;
PDBTitle: crystal structure of human beta-galactosidase in complex with 1-2 deoxygalactonojirimycin
37d1tvna1
not modelled 99.9 17 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
38c2cksB_
not modelled 99.9 18 PDB header:hydrolase
Chain: B: PDB Molecule:endoglucanase e-5;
PDBTitle: x-ray crystal structure of the catalytic domain of2 thermobifida fusca endoglucanase cel5a (e5)
39d1bqca_
not modelled 99.9 20 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
40d1ecea_
not modelled 99.9 16 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
41c1wkyA_
not modelled 99.9 16 PDB header:hydrolase
Chain: A: PDB Molecule:endo-beta-1,4-mannanase;
PDBTitle: crystal structure of alkaline mannanase from bacillus sp. strain jamb-2 602: catalytic domain and its carbohydrate binding module
42d1kwga2
not modelled 99.9 13 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
43c2zunB_
not modelled 99.9 19 PDB header:hydrolase
Chain: B: PDB Molecule:458aa long hypothetical endo-1,4-beta-glucanase;
PDBTitle: functional analysis of hyperthermophilic endocellulase from2 the archaeon pyrococcus horikoshii
44d1tg7a2
not modelled 99.9 17 Fold:Galactose-binding domain-like
Superfamily:Galactose-binding domain-like
Family:Beta-galactosidase LacA, domains 4 and 5
45c3d3aA_
not modelled 99.9 12 PDB header:hydrolase
Chain: A: PDB Molecule:beta-galactosidase;
PDBTitle: crystal structure of a beta-galactosidase from bacteroides2 thetaiotaomicron
46c3pzqA_
not modelled 99.9 16 PDB header:hydrolase
Chain: A: PDB Molecule:mannan endo-1,4-beta-mannosidase. glycosyl hydrolase family
PDBTitle: structure of the hyperthermostable endo-1,4-beta-d-mannanase from2 thermotoga petrophila rku-1 with maltose and glycerol
47c2oylB_
not modelled 99.9 17 PDB header:hydrolase
Chain: B: PDB Molecule:endoglycoceramidase ii;
PDBTitle: endo-glycoceramidase ii from rhodococcus sp.: cellobiose-like2 imidazole complex
48d1hjqa_
not modelled 99.9 14 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
49d1hjsa_
not modelled 99.8 16 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
50d1vbua1
not modelled 99.8 17 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
51d1g01a_
not modelled 99.8 21 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
52d1v6ya_
not modelled 99.8 15 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
53c1kwgA_
not modelled 99.8 14 PDB header:hydrolase
Chain: A: PDB Molecule:beta-galactosidase;
PDBTitle: crystal structure of thermus thermophilus a4 beta-galactosidase
54d1fh9a_
not modelled 99.8 16 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
55d1nq6a_
not modelled 99.8 17 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
56d1w91a2
not modelled 99.8 14 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
57c3ogrA_
not modelled 99.8 11 PDB header:hydrolase
Chain: A: PDB Molecule:beta-galactosidase;
PDBTitle: complex structure of beta-galactosidase from trichoderma reesei with2 galactose
58d1uhva2
not modelled 99.8 13 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
59d1n82a_
not modelled 99.8 16 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
60d1vjza_
not modelled 99.8 19 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
61c1xc6A_
not modelled 99.8 12 PDB header:hydrolase
Chain: A: PDB Molecule:beta-galactosidase;
PDBTitle: native structure of beta-galactosidase from penicillium sp. in complex2 with galactose
62c3emzA_
not modelled 99.8 15 PDB header:hydrolase
Chain: A: PDB Molecule:endo-1,4-beta-xylanase;
PDBTitle: crystal structure of xylanase xynb from paenibacillus2 barcinonensis complexed with a conduramine derivative
63d1v6wa2
not modelled 99.8 16 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
64d1ur4a_
not modelled 99.8 18 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
65d1us3a2
not modelled 99.8 14 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
66d1w32a_
not modelled 99.8 17 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
67c1xyzA_
not modelled 99.8 14 PDB header:glycosyltransferase
Chain: A: PDB Molecule:1,4-beta-d-xylan-xylanohydrolase;
PDBTitle: a common protein fold and similar active site in two2 distinct families of beta-glycanases
68d1xyza_
not modelled 99.8 14 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
69c2depA_
not modelled 99.8 17 PDB header:hydrolase
Chain: A: PDB Molecule:thermostable celloxylanase;
PDBTitle: crystal structure of xylanase b from clostridium2 stercorarium f9
70d1v0la_
not modelled 99.8 17 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
71c2jepB_
not modelled 99.7 13 PDB header:hydrolase
Chain: B: PDB Molecule:xyloglucanase;
PDBTitle: native family 5 xyloglucanase from paenibacillus pabuli
72c2cncA_
not modelled 99.7 15 PDB header:hydrolase
Chain: A: PDB Molecule:endoxylanase;
PDBTitle: family 10 xylanase
73c2bs9B_
not modelled 99.7 16 PDB header:hydrolase
Chain: B: PDB Molecule:beta-xylosidase;
PDBTitle: native crystal structure of a gh39 beta-xylosidase xynb12 from geobacillus stearothermophilus
74d1ceoa_
not modelled 99.7 17 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
75d1ta3b_
not modelled 99.7 18 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
76d1h1na_
not modelled 99.7 13 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
77c3ncoA_
not modelled 99.7 19 PDB header:hydrolase
Chain: A: PDB Molecule:endoglucanase fncel5a;
PDBTitle: crystal structure of fncel5a from f. nodosum rt17-b1
78d1ur1a_
not modelled 99.7 16 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
79d1i1wa_
not modelled 99.7 18 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
80d1foba_
not modelled 99.7 14 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
81c3aysA_
not modelled 99.7 18 PDB header:hydrolase
Chain: A: PDB Molecule:endoglucanase;
PDBTitle: gh5 endoglucanase from a ruminal fungus in complex with cellotriose
82d2pb1a1
not modelled 99.7 16 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
83c3ndyA_
not modelled 99.7 17 PDB header:hydrolase
Chain: A: PDB Molecule:endoglucanase d;
PDBTitle: the structure of the catalytic and carbohydrate binding domain of2 endoglucanase d from clostridium cellulovorans
84d1bg4a_
not modelled 99.7 18 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
85c1uhvD_
not modelled 99.7 14 PDB header:hydrolase
Chain: D: PDB Molecule:beta-xylosidase;
PDBTitle: crystal structure of beta-d-xylosidase from2 thermoanaerobacterium saccharolyticum, a family 393 glycoside hydrolase
86c2y8kA_
not modelled 99.7 21 PDB header:hydrolase
Chain: A: PDB Molecule:carbohydrate binding family 6;
PDBTitle: structure of ctgh5-cbm6, an arabinoxylan-specific xylanase.
87c3qr3B_
not modelled 99.7 15 PDB header:hydrolase
Chain: B: PDB Molecule:endoglucanase eg-ii;
PDBTitle: crystal structure of cel5a (eg2) from hypocrea jecorina (trichoderma2 reesei)
88c3l55B_
not modelled 99.7 14 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:b-1,4-endoglucanase/cellulase;
PDBTitle: crystal structure of a putative beta-1,4-endoglucanase /2 cellulase from prevotella bryantii
89c3mmwB_
not modelled 99.7 19 PDB header:hydrolase
Chain: B: PDB Molecule:endoglucanase;
PDBTitle: crystal structure of endoglucanase cel5a from the hyperthermophilic2 thermotoga maritima
90c3icgD_
not modelled 99.6 16 PDB header:hydrolase
Chain: D: PDB Molecule:endoglucanase d;
PDBTitle: crystal structure of the catalytic and carbohydrate binding domain of2 endoglucanase d from clostridium cellulovorans
91d1tuxa_
not modelled 99.6 16 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
92d1edga_
not modelled 99.6 14 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
93c2fglA_
not modelled 99.6 14 PDB header:hydrolase
Chain: A: PDB Molecule:alkaline thermostable endoxylanase;
PDBTitle: an alkali thermostable f/10 xylanase from alkalophilic2 bacillus sp. ng-27
94d1ug6a_
not modelled 99.6 21 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Family 1 of glycosyl hydrolase
95c3ahxC_
not modelled 99.6 18 PDB header:hydrolase
Chain: C: PDB Molecule:beta-glucosidase a;
PDBTitle: crystal structure of beta-glucosidase a from bacterium clostridium2 cellulovorans
96d1e4ia_
not modelled 99.6 19 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Family 1 of glycosyl hydrolase
97c2j75A_
not modelled 99.6 20 PDB header:hydrolase
Chain: A: PDB Molecule:beta-glucosidase a;
PDBTitle: beta-glucosidase from thermotoga maritima in complex with2 noeuromycin
98d1r85a_
not modelled 99.6 18 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
99d1h4pa_
not modelled 99.6 14 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
100c2z1sA_
not modelled 99.6 23 PDB header:hydrolase
Chain: A: PDB Molecule:beta-glucosidase b;
PDBTitle: beta-glucosidase b from paenibacillus polymyxa complexed2 with cellotetraose
101d1jz8a1
not modelled 99.5 29 Fold:Immunoglobulin-like beta-sandwich
Superfamily:beta-Galactosidase/glucuronidase domain
Family:beta-Galactosidase/glucuronidase domain
102d1qoxa_
not modelled 99.5 21 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Family 1 of glycosyl hydrolase
103c3qomA_
not modelled 99.5 19 PDB header:hydrolase
Chain: A: PDB Molecule:6-phospho-beta-glucosidase;
PDBTitle: crystal structure of 6-phospho-beta-glucosidase from lactobacillus2 plantarum
104d1vffa1
not modelled 99.5 22 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Family 1 of glycosyl hydrolase
105c3fiyA_
not modelled 99.5 20 PDB header:hydrolase
Chain: A: PDB Molecule:beta-glucosidase;
PDBTitle: crystal structure of bglb
106c2w5fB_
not modelled 99.5 17 PDB header:hydrolase
Chain: B: PDB Molecule:endo-1,4-beta-xylanase y;
PDBTitle: high resolution crystallographic structure of the2 clostridium thermocellum n-terminal endo-1,4-beta-d-3 xylanase 10b (xyn10b) cbm22-1-gh10 modules complexed with4 xylohexaose
107c3u7vA_
not modelled 99.5 15 PDB header:hydrolase
Chain: A: PDB Molecule:beta-galactosidase;
PDBTitle: the structure of a putative beta-galactosidase from caulobacter2 crescentus cb15.
108d1pbga_
not modelled 99.4 18 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Family 1 of glycosyl hydrolase
109c3pn8A_
not modelled 99.4 20 PDB header:hydrolase
Chain: A: PDB Molecule:putative phospho-beta-glucosidase;
PDBTitle: the crystal structure of 6-phospho-beta-glucosidase from streptococcus2 mutans ua159
110d1tg7a3
not modelled 99.4 11 Fold:Galactose-binding domain-like
Superfamily:Galactose-binding domain-like
Family:Beta-galactosidase LacA, domains 4 and 5
111d2j78a1
not modelled 99.4 20 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Family 1 of glycosyl hydrolase
112d1gnxa_
not modelled 99.4 23 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Family 1 of glycosyl hydrolase
113d1qvba_
not modelled 99.4 22 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Family 1 of glycosyl hydrolase
114d1aq0a_
not modelled 99.4 14 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:beta-glycanases
115c2xhyD_
not modelled 99.4 20 PDB header:hydrolase
Chain: D: PDB Molecule:6-phospho-beta-glucosidase bgla;
PDBTitle: crystal structure of e.coli bgla
116c3kzsD_
not modelled 99.4 18 PDB header:hydrolase
Chain: D: PDB Molecule:glycosyl hydrolase family 5;
PDBTitle: crystal structure of glycosyl hydrolase family 5 (np_809925.1) from2 bacteroides thetaiotaomicron vpi-5482 at 2.10 a resolution
117c2dgaA_
not modelled 99.4 22 PDB header:hydrolase
Chain: A: PDB Molecule:beta-glucosidase;
PDBTitle: crystal structure of hexameric beta-glucosidase in wheat
118d1v02a_
not modelled 99.4 21 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Family 1 of glycosyl hydrolase
119c1v02F_
not modelled 99.4 21 PDB header:hydrolase
Chain: F: PDB Molecule:dhurrinase;
PDBTitle: crystal structure of the sorghum bicolor dhurrinase 1
120d1uwsa_
not modelled 99.4 21 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Family 1 of glycosyl hydrolase

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0