Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP25889
DateThu Jan 5 11:42:42 GMT 2012
Unique Job ID67679a0c70f61f3e

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1gthD_
Top template information
PDB header:oxidoreductase
Chain: D: PDB Molecule:dihydropyrimidine dehydrogenase;
PDBTitle: dihydropyrimidine dehydrogenase (dpd) from pig, ternary2 complex with nadph and 5-iodouracil
Confidence and coverage
Confidence:100.0% Coverage: 95%
390 residues ( 95% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MLTKDLSITFCGVKFPNPFCLSSSPVGNCYEMCAKAYDTGWGGVVFKTIGFFIANEVSPR
Secondary structure 
SS confidence 
Disorder  ??????
???????
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  FDHLVKEDTGFIGFKNMEQIAEHPLEENLAALRRLKEDYPDKVLIASIMGENEQQWEELA
Secondary structure 
SS confidence 
Disorder 
??????
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  RLVQEAGADMIECNFSCPQMTSHAMGSDVGQSPELVEKYCRAVKRGSTLPMLAKMTPNIG
Secondary structure 
SS confidence 
Disorder 
???????
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  DMCEVALAAKRGGADGIAAINTVKSITNIDLNQKIGMPIVNGKSSISGYSGKAVKPIALR
Secondary structure 
SS confidence 
Disorder 
??
?
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  FIQQMRTHPELRDFPISGIGGIETWEDAAEFLLLGAATLQVTTGIMQYGYRIVEDMASGL
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  SHYLADQGFDSLQEMVGLANNNIVPAEDLDRSYIVYPRINLDKCVGCGRCYISCYDGGHQ
Secondary structure 
SS confidence 
Disorder 
?
?
????
Disorder confidence 
 
   .........370.........380.........390.........400.........410.
Sequence  AMEWSEKTRTPHCNTEKCVGCLLCGHVCPVGCIELGEVKFKKGEKEHPVTL
Secondary structure 
SS confidence 
Disorder 
??????????????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1gth chain D

3D model

Region: 5 - 397
Aligned: 390
Modelled: 393
Confidence: 100.0%
Identity: 37%
PDB header:oxidoreductase
Chain: D: PDB Molecule:dihydropyrimidine dehydrogenase;
PDBTitle: dihydropyrimidine dehydrogenase (dpd) from pig, ternary2 complex with nadph and 5-iodouracil

Phyre2

PDB 1tv5 chain A domain 1

3D model

Region: 3 - 320
Aligned: 301
Modelled: 318
Confidence: 100.0%
Identity: 22%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 1tv5 chain A

3D model

Region: 3 - 320
Aligned: 301
Modelled: 318
Confidence: 100.0%
Identity: 22%
PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydroorotate dehydrogenase homolog, mitochondrial;
PDBTitle: plasmodium falciparum dihydroorotate dehydrogenase with a bound2 inhibitor

Phyre2

PDB 1d3g chain A

3D model

Region: 5 - 322
Aligned: 306
Modelled: 317
Confidence: 100.0%
Identity: 22%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 2fpt chain A

3D model

Region: 2 - 322
Aligned: 310
Modelled: 318
Confidence: 100.0%
Identity: 21%
PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydroorotate dehydrogenase, mitochondrial;
PDBTitle: dual binding mode of a novel series of dhodh inhibitors

Phyre2

PDB 1uum chain A

3D model

Region: 3 - 322
Aligned: 300
Modelled: 320
Confidence: 100.0%
Identity: 24%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 1f76 chain A

3D model

Region: 1 - 300
Aligned: 278
Modelled: 300
Confidence: 100.0%
Identity: 22%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 3oix chain A

3D model

Region: 5 - 320
Aligned: 298
Modelled: 312
Confidence: 100.0%
Identity: 21%
PDB header:oxidoreductase
Chain: A: PDB Molecule:putative dihydroorotate dehydrogenase; dihydroorotate
PDBTitle: crystal structure of the putative dihydroorotate dehydrogenase from2 streptococcus mutans

Phyre2

PDB 1jub chain A

3D model

Region: 6 - 321
Aligned: 304
Modelled: 316
Confidence: 100.0%
Identity: 24%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 2b4g chain A domain 1

3D model

Region: 6 - 320
Aligned: 301
Modelled: 312
Confidence: 100.0%
Identity: 22%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 3gye chain A

3D model

Region: 5 - 319
Aligned: 288
Modelled: 293
Confidence: 100.0%
Identity: 22%
PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydroorotate dehydrogenase, putative;
PDBTitle: didydroorotate dehydrogenase from leishmania major

Phyre2

PDB 1ep3 chain A

3D model

Region: 3 - 322
Aligned: 304
Modelled: 320
Confidence: 100.0%
Identity: 25%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 1gte chain A domain 2

3D model

Region: 6 - 310
Aligned: 299
Modelled: 305
Confidence: 100.0%
Identity: 36%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 2zrv chain C

3D model

Region: 5 - 316
Aligned: 277
Modelled: 284
Confidence: 100.0%
Identity: 17%
PDB header:isomerase
Chain: C: PDB Molecule:isopentenyl-diphosphate delta-isomerase;
PDBTitle: crystal structure of sulfolobus shibatae isopentenyl2 diphosphate isomerase in complex with reduced fmn.

Phyre2

PDB 1vcf chain A domain 1

3D model

Region: 5 - 320
Aligned: 261
Modelled: 269
Confidence: 100.0%
Identity: 21%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 1gox chain A

3D model

Region: 3 - 316
Aligned: 245
Modelled: 250
Confidence: 100.0%
Identity: 22%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 2rdu chain A

3D model

Region: 3 - 322
Aligned: 283
Modelled: 295
Confidence: 100.0%
Identity: 16%
PDB header:oxidoreductase
Chain: A: PDB Molecule:hydroxyacid oxidase 1;
PDBTitle: crystal structure of human glycolate oxidase in complex with2 glyoxylate

Phyre2

PDB 2e77 chain B

3D model

Region: 3 - 329
Aligned: 283
Modelled: 295
Confidence: 100.0%
Identity: 14%
PDB header:oxidoreductase
Chain: B: PDB Molecule:lactate oxidase;
PDBTitle: crystal structure of l-lactate oxidase with pyruvate complex

Phyre2

PDB 1tb3 chain A domain 1

3D model

Region: 3 - 321
Aligned: 250
Modelled: 255
Confidence: 100.0%
Identity: 16%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 1kbi chain B

3D model

Region: 3 - 337
Aligned: 292
Modelled: 313
Confidence: 100.0%
Identity: 17%
PDB header:oxidoreductase
Chain: B: PDB Molecule:cytochrome b2;
PDBTitle: crystallographic study of the recombinant flavin-binding domain of2 baker's yeast flavocytochrome b2: comparison with the intact wild-3 type enzyme

Phyre2
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c1gthD_
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d1tv5a1
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c1tv5A_
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d1d3ga_
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c2fptA_
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d1uuma_
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d1f76a_
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c3oixA_
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d1juba_
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d2b4ga1
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c3gyeA_
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d1ep3a_
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d1gtea2
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c2zrvC_
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d1vcfa1
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d1goxa_
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c2rduA_
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c2e77B_
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d1tb3a1
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c1kbiB_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1gthD_
100.0 37 PDB header:oxidoreductase
Chain: D: PDB Molecule:dihydropyrimidine dehydrogenase;
PDBTitle: dihydropyrimidine dehydrogenase (dpd) from pig, ternary2 complex with nadph and 5-iodouracil
2d1tv5a1
100.0 22 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
3c1tv5A_
100.0 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydroorotate dehydrogenase homolog, mitochondrial;
PDBTitle: plasmodium falciparum dihydroorotate dehydrogenase with a bound2 inhibitor
4d1d3ga_
100.0 22 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
5c2fptA_
100.0 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydroorotate dehydrogenase, mitochondrial;
PDBTitle: dual binding mode of a novel series of dhodh inhibitors
6d1uuma_
100.0 24 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
7d1f76a_
100.0 22 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
8c3oixA_
100.0 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative dihydroorotate dehydrogenase; dihydroorotate
PDBTitle: crystal structure of the putative dihydroorotate dehydrogenase from2 streptococcus mutans
9d1juba_
100.0 24 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
10d2b4ga1
100.0 22 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
11c3gyeA_
100.0 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydroorotate dehydrogenase, putative;
PDBTitle: didydroorotate dehydrogenase from leishmania major
12d1ep3a_
100.0 25 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
13d1gtea2
100.0 36 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
14c2zrvC_
100.0 17 PDB header:isomerase
Chain: C: PDB Molecule:isopentenyl-diphosphate delta-isomerase;
PDBTitle: crystal structure of sulfolobus shibatae isopentenyl2 diphosphate isomerase in complex with reduced fmn.
15d1vcfa1
100.0 21 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
16d1goxa_
100.0 22 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
17c2rduA_
100.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:hydroxyacid oxidase 1;
PDBTitle: crystal structure of human glycolate oxidase in complex with2 glyoxylate
18c2e77B_
100.0 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:lactate oxidase;
PDBTitle: crystal structure of l-lactate oxidase with pyruvate complex
19d1tb3a1
100.0 16 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
20c1kbiB_
100.0 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:cytochrome b2;
PDBTitle: crystallographic study of the recombinant flavin-binding domain of2 baker's yeast flavocytochrome b2: comparison with the intact wild-3 type enzyme
21d1p4ca_
not modelled 100.0 13 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
22d1p0ka_
not modelled 100.0 17 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
23c2a7nA_
not modelled 100.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:l(+)-mandelate dehydrogenase;
PDBTitle: crystal structure of the g81a mutant of the active chimera of (s)-2 mandelate dehydrogenase
24d1kbia1
not modelled 100.0 15 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
25d1vhna_
not modelled 99.9 19 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
26c3khjE_
not modelled 99.9 19 PDB header:oxidoreductase
Chain: E: PDB Molecule:inosine-5-monophosphate dehydrogenase;
PDBTitle: c. parvum inosine monophosphate dehydrogenase bound by inhibitor c64
27c3b0vD_
not modelled 99.9 14 PDB header:oxidoreductase/rna
Chain: D: PDB Molecule:trna-dihydrouridine synthase;
PDBTitle: trna-dihydrouridine synthase from thermus thermophilus in complex with2 trna
28d1eepa_
not modelled 99.9 18 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
29c1vrdA_
not modelled 99.9 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine-5'-monophosphate dehydrogenase;
PDBTitle: crystal structure of inosine-5'-monophosphate dehydrogenase (tm1347)2 from thermotoga maritima at 2.18 a resolution
30d1jr1a1
not modelled 99.9 20 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
31d1vrda1
not modelled 99.9 20 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
32c2qr6A_
not modelled 99.9 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:imp dehydrogenase/gmp reductase;
PDBTitle: crystal structure of imp dehydrogenase/gmp reductase-like protein2 (np_599840.1) from corynebacterium glutamicum atcc 13032 kitasato at3 1.50 a resolution
33d1jcna1
not modelled 99.9 20 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
34d1zfja1
not modelled 99.9 21 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
35c3ffsC_
not modelled 99.9 22 PDB header:oxidoreductase
Chain: C: PDB Molecule:inosine-5-monophosphate dehydrogenase;
PDBTitle: the crystal structure of cryptosporidium parvum inosine-5'-2 monophosphate dehydrogenase
36c1ypfB_
not modelled 99.9 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:gmp reductase;
PDBTitle: crystal structure of guac (ba5705) from bacillus anthracis at 1.8 a2 resolution
37c1jcnA_
not modelled 99.9 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine monophosphate dehydrogenase i;
PDBTitle: binary complex of human type-i inosine monophosphate dehydrogenase2 with 6-cl-imp
38c3gr7A_
not modelled 99.9 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadph dehydrogenase;
PDBTitle: structure of oye from geobacillus kaustophilus, hexagonal2 crystal form
39c3r2gA_
not modelled 99.9 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine 5'-monophosphate dehydrogenase;
PDBTitle: crystal structure of inosine 5' monophosphate dehydrogenase from2 legionella pneumophila
40c1me9A_
not modelled 99.9 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine-5'-monophosphate dehydrogenase;
PDBTitle: inosine monophosphate dehydrogenase (impdh) from2 tritrichomonas foetus with imp bound
41c2a7rD_
not modelled 99.9 16 PDB header:oxidoreductase
Chain: D: PDB Molecule:gmp reductase 2;
PDBTitle: crystal structure of human guanosine monophosphate2 reductase 2 (gmpr2)
42d1pvna1
not modelled 99.9 17 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
43d2cu0a1
not modelled 99.9 21 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
44d1geqa_
not modelled 99.9 17 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
45c2cu0B_
not modelled 99.9 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:inosine-5'-monophosphate dehydrogenase;
PDBTitle: crystal structure of inosine-5'-monophosphate dehydrogenase from2 pyrococcus horikoshii ot3
46c3hf3A_
not modelled 99.9 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:chromate reductase;
PDBTitle: old yellow enzyme from thermus scotoductus sa-01
47c2cdh1_
not modelled 99.9 21 PDB header:transferase
Chain: 1: PDB Molecule:enoyl reductase;
PDBTitle: architecture of the thermomyces lanuginosus fungal fatty2 acid synthase at 5 angstrom resolution.
48d1ps9a1
not modelled 99.9 16 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
49c2h90A_
not modelled 99.9 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:xenobiotic reductase a;
PDBTitle: xenobiotic reductase a in complex with coumarin
50c3kruC_
not modelled 99.9 16 PDB header:oxidoreductase
Chain: C: PDB Molecule:nadh:flavin oxidoreductase/nadh oxidase;
PDBTitle: crystal structure of the thermostable old yellow enzyme from2 thermoanaerobacter pseudethanolicus e39
51c2htmB_
not modelled 99.9 17 PDB header:biosynthetic protein
Chain: B: PDB Molecule:thiazole biosynthesis protein thig;
PDBTitle: crystal structure of ttha0676 from thermus thermophilus hb8
52d1z41a1
not modelled 99.8 20 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
53c1zfjA_
not modelled 99.8 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine monophosphate dehydrogenase;
PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes
54d1djqa1
not modelled 99.8 13 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
55c1ps9A_
not modelled 99.8 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:2,4-dienoyl-coa reductase;
PDBTitle: the crystal structure and reaction mechanism of e. coli 2,4-2 dienoyl coa reductase
56c1djnB_
not modelled 99.8 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:trimethylamine dehydrogenase;
PDBTitle: structural and biochemical characterization of recombinant wild type2 trimethylamine dehydrogenase from methylophilus methylotrophus (sp.3 w3a1)
57d1rd5a_
not modelled 99.8 18 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
58c2gjlA_
not modelled 99.7 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:hypothetical protein pa1024;
PDBTitle: crystal structure of 2-nitropropane dioxygenase
59c2z6jB_
not modelled 99.7 22 PDB header:oxidoreductase
Chain: B: PDB Molecule:trans-2-enoyl-acp reductase ii;
PDBTitle: crystal structure of s. pneumoniae enoyl-acyl carrier2 protein reductase (fabk) in complex with an inhibitor
60d1gwja_
not modelled 99.7 19 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
61d1gtea5
not modelled 99.7 32 Fold:Ferredoxin-like
Superfamily:4Fe-4S ferredoxins
Family:Ferredoxin domains from multidomain proteins
62c3bo9B_
not modelled 99.7 21 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative nitroalkan dioxygenase;
PDBTitle: crystal structure of putative nitroalkan dioxygenase (tm0800) from2 thermotoga maritima at 2.71 a resolution
63d1vyra_
not modelled 99.7 17 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
64c3k30B_
not modelled 99.7 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:histamine dehydrogenase;
PDBTitle: histamine dehydrogenase from nocardiodes simplex
65c2gq8A_
not modelled 99.7 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase, fmn-binding;
PDBTitle: structure of sye1, an oye homologue from s. ondeidensis, in complex2 with p-hydroxyacetophenone
66c3bw2A_
not modelled 99.6 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-nitropropane dioxygenase;
PDBTitle: crystal structures and site-directed mutagenesis study of nitroalkane2 oxidase from streptomyces ansochromogenes
67d1xm3a_
not modelled 99.6 17 Fold:TIM beta/alpha-barrel
Superfamily:ThiG-like
Family:ThiG-like
68c3gkaB_
not modelled 99.6 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:n-ethylmaleimide reductase;
PDBTitle: crystal structure of n-ethylmaleimidine reductase from2 burkholderia pseudomallei
69d1oyaa_
not modelled 99.6 10 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
70d1vjia_
not modelled 99.6 15 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
71c2c3yA_
not modelled 99.5 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:pyruvate-ferredoxin oxidoreductase;
PDBTitle: crystal structure of the radical form of2 pyruvate:ferredoxin oxidoreductase from desulfovibrio3 africanus
72d1icpa_
not modelled 99.5 15 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
73c3atyA_
not modelled 99.5 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:prostaglandin f2a synthase;
PDBTitle: crystal structure of tcoye
74d1ofda2
not modelled 99.5 19 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
75c3l5aA_
not modelled 99.5 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadh/flavin oxidoreductase/nadh oxidase;
PDBTitle: crystal structure of a probable nadh-dependent flavin oxidoreductase2 from staphylococcus aureus
76d1ea0a2
not modelled 99.5 18 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
77d1y0ea_
not modelled 99.4 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:NanE-like
78d1xcfa_
not modelled 99.4 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
79d1qopa_
not modelled 99.4 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
80c2gmhA_
not modelled 99.4 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:electron transfer flavoprotein-ubiquinone
PDBTitle: structure of porcine electron transfer flavoprotein-2 ubiquinone oxidoreductase in complexed with ubiquinone
81c2vdcF_
not modelled 99.3 19 PDB header:oxidoreductase
Chain: F: PDB Molecule:glutamate synthase [nadph] large chain;
PDBTitle: the 9.5 a resolution structure of glutamate synthase from2 cryo-electron microscopy and its oligomerization behavior3 in solution: functional implications.
82c3q58A_
not modelled 99.3 18 PDB header:isomerase
Chain: A: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase;
PDBTitle: structure of n-acetylmannosamine-6-phosphate epimerase from salmonella2 enterica
83d1q45a_
not modelled 99.3 13 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
84c2fugG_
not modelled 99.3 33 PDB header:oxidoreductase
Chain: G: PDB Molecule:nadh-quinone oxidoreductase chain 9;
PDBTitle: crystal structure of the hydrophilic domain of respiratory complex i2 from thermus thermophilus
85d2fug91
not modelled 99.3 33 Fold:Ferredoxin-like
Superfamily:4Fe-4S ferredoxins
Family:Ferredoxin domains from multidomain proteins
86d1hfel2
not modelled 99.3 23 Fold:Ferredoxin-like
Superfamily:4Fe-4S ferredoxins
Family:Ferredoxin domains from multidomain proteins
87d1yxya1
not modelled 99.3 20 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:NanE-like
88c1lm1A_
not modelled 99.3 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:ferredoxin-dependent glutamate synthase;
PDBTitle: structural studies on the synchronization of catalytic centers in2 glutamate synthase: native enzyme
89c3navB_
not modelled 99.3 16 PDB header:lyase
Chain: B: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: crystal structure of an alpha subunit of tryptophan synthase from2 vibrio cholerae o1 biovar el tor str. n16961
90d1xera_
not modelled 99.2 25 Fold:Ferredoxin-like
Superfamily:4Fe-4S ferredoxins
Family:Archaeal ferredoxins
91c2c3zA_
not modelled 99.2 18 PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus
92d1wa3a1
not modelled 99.2 15 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
93c2v82A_
not modelled 99.2 18 PDB header:lyase
Chain: A: PDB Molecule:2-dehydro-3-deoxy-6-phosphogalactonate aldolase;
PDBTitle: kdpgal complexed to kdpgal
94d2c42a5
not modelled 99.2 28 Fold:Ferredoxin-like
Superfamily:4Fe-4S ferredoxins
Family:Ferredoxin domains from multidomain proteins
95c3gyxJ_
not modelled 99.2 27 PDB header:oxidoreductase
Chain: J: PDB Molecule:adenylylsulfate reductase;
PDBTitle: crystal structure of adenylylsulfate reductase from2 desulfovibrio gigas
96d7fd1a_
not modelled 99.2 22 Fold:Ferredoxin-like
Superfamily:4Fe-4S ferredoxins
Family:7-Fe ferredoxin
97c2ekcA_
not modelled 99.2 16 PDB header:lyase
Chain: A: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5
98d1wv2a_
not modelled 99.2 15 Fold:TIM beta/alpha-barrel
Superfamily:ThiG-like
Family:ThiG-like
99c3igsB_
not modelled 99.2 16 PDB header:isomerase
Chain: B: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase 2;
PDBTitle: structure of the salmonella enterica n-acetylmannosamine-6-phosphate2 2-epimerase
100d1jb0c_
not modelled 99.1 22 Fold:Ferredoxin-like
Superfamily:4Fe-4S ferredoxins
Family:7-Fe ferredoxin
101c1hfeL_
not modelled 99.1 23 PDB header:hydrogenase
Chain: L: PDB Molecule:protein (fe-only hydrogenase (e.c.1.18.99.1)
PDBTitle: 1.6 a resolution structure of the fe-only hydrogenase from2 desulfovibrio desulfuricans
102d1rpxa_
not modelled 99.1 19 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
103d1jnrb_
not modelled 99.1 23 Fold:Ferredoxin-like
Superfamily:4Fe-4S ferredoxins
Family:Ferredoxin domains from multidomain proteins
104c3thaB_
not modelled 99.1 19 PDB header:lyase
Chain: B: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: tryptophan synthase subunit alpha from campylobacter jejuni.
105d1ka9f_
not modelled 99.1 21 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
106c1gx7A_
not modelled 99.1 28 PDB header:oxidoreductase
Chain: A: PDB Molecule:periplasmic [fe] hydrogenase large subunit;
PDBTitle: best model of the electron transfer complex between2 cytochrome c3 and [fe]-hydrogenase
107d1dura_
not modelled 99.1 27 Fold:Ferredoxin-like
Superfamily:4Fe-4S ferredoxins
Family:Short-chain ferredoxins
108c3qc3B_
not modelled 99.1 10 PDB header:isomerase
Chain: B: PDB Molecule:d-ribulose-5-phosphate-3-epimerase;
PDBTitle: crystal structure of a d-ribulose-5-phosphate-3-epimerase (np_954699)2 from homo sapiens at 2.20 a resolution
109d1bc6a_
not modelled 99.1 24 Fold:Ferredoxin-like
Superfamily:4Fe-4S ferredoxins
Family:7-Fe ferredoxin
110d1h98a_
not modelled 99.1 22 Fold:Ferredoxin-like
Superfamily:4Fe-4S ferredoxins
Family:7-Fe ferredoxin
111d1h1ya_
not modelled 99.1 12 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
112d1h5ya_
not modelled 99.0 18 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
113c3qjaA_
not modelled 99.0 17 PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of the mycobacterium tuberculosis indole-3-glycerol2 phosphate synthase (trpc) in apo form
114d2flia1
not modelled 99.0 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
115d1y5ib1
not modelled 99.0 18 Fold:Ferredoxin-like
Superfamily:4Fe-4S ferredoxins
Family:Ferredoxin domains from multidomain proteins
116d1wbha1
not modelled 99.0 8 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
117d1thfd_
not modelled 99.0 19 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
118d1a53a_
not modelled 99.0 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
119d2fug34
not modelled 99.0 13 Fold:Ferredoxin-like
Superfamily:4Fe-4S ferredoxins
Family:Ferredoxin domains from multidomain proteins
120d3c8ya3
not modelled 99.0 23 Fold:Ferredoxin-like
Superfamily:4Fe-4S ferredoxins
Family:Ferredoxin domains from multidomain proteins

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0