Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	E	L	N	D	L	L	T	T	R	E	L	Q	R	W	R	L	I	L	G	E	A	A	E	T	T	L	C	G	L	D	D	N	A	R	Q	I	D	H	A	L	E	W	L	Y	G	R	D	P	E	R	L	Q	R	G	E	R	S	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?		?	?		?										?		?	?	?	?	?	?	?	?	?	?													?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	L	G	G	S	N	L	T	T	P	E	W	I	N	S	I	H	T	L	F	P	Q	Q	V	I	E	R	L	E	S	D	A	V	L	R	Y	G	I	E	D	V	V	T	N	L	D	V	L	E	R	M	Q	P	S	E	S	L	L	R	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?																										?		?		?		?	?								?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	L	H	T	K	H	L	M	N	P	E	V	L	A	A	A	R	R	I	V	C	Q	V	V	E	E	I	M	A	R	L	A	K	E	V	R	Q	A	F	S	G	V	R	D	R	R	R	R	S	F	I	P	L	A	R	N	F	D	F	K
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?																													?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		S	T	L	R	A	N	L	Q	H	W	H	P	Q	H	G	K	L	Y	I	E	S	P	R	F	N	S	R	I	K	R	Q	S	E	Q	W	Q	L	V	L	L	V	D	Q	S	G	S	M	V	D	S	V	I	H	S	A	V	M	A	A	C
Secondary structure
SS confidence
Disorder																?								?	?	?		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		L	W	Q	L	P	G	I	R	T	H	L	V	A	F	D	T	S	V	V	D	L	T	A	D	V	A	D	P	V	E	L	L	M	K	V	Q	L	G	G	G	T	N	I	A	S	A	V	E	Y	G	R	Q	L	I	E	Q	P	A	K	S
Secondary structure
SS confidence
Disorder			?																																		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		V	I	I	L	V	S	D	F	Y	E	G	G	S	S	S	L	L	T	H	Q	V	K	K	C	V	Q	S	G	I	K	V	L	G	L	A	A	L	D	S	T	A	T	P	C	Y	D	R	D	T	A	Q	A	L	V	N	V	G	A	Q	I
Secondary structure
SS confidence
Disorder																																									?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.
Sequence		A	A	M	T	P	G	E	L	A	S	W	L	A	E	N	L	Q	S
Secondary structure
SS confidence
Disorder																	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2nvo chain A Region: 81 - 378 Aligned: 281 Modelled: 298 Confidence: 99.7% Identity: 14% PDB header:rna binding protein Chain: A: PDB Molecule:ro sixty-related protein, rsr; PDBTitle: crystal structure of deinococcus radiodurans ro (rsr) protein Phyre2 PDB 3ibs chain A Region: 213 - 376 Aligned: 162 Modelled: 164 Confidence: 99.7% Identity: 16% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved hypothetical protein batb; PDBTitle: crystal structure of conserved hypothetical protein batb from2 bacteroides thetaiotaomicron Phyre2 PDB 2x5n chain A Region: 217 - 373 Aligned: 153 Modelled: 157 Confidence: 99.6% Identity: 11% PDB header:nuclear protein Chain: A: PDB Molecule:26s proteasome regulatory subunit rpn10; PDBTitle: crystal structure of the sprpn10 vwa domain Phyre2 PDB 2i6s chain A Region: 208 - 376 Aligned: 159 Modelled: 167 Confidence: 99.6% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:complement c2a fragment; PDBTitle: complement component c2a Phyre2 PDB 1rs0 chain A Region: 216 - 376 Aligned: 156 Modelled: 161 Confidence: 99.6% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:complement factor b; PDBTitle: crystal structure analysis of the bb segment of factor b2 complexed with di-isopropyl-phosphate (dip) Phyre2 PDB 2x31 chain F Region: 210 - 378 Aligned: 163 Modelled: 169 Confidence: 99.6% Identity: 19% PDB header:ligase Chain: F: PDB Molecule:magnesium-chelatase 60 kda subunit; PDBTitle: modelling of the complex between subunits bchi and bchd of magnesium2 chelatase based on single-particle cryo-em reconstruction at 7.5 ang Phyre2 PDB 2ok5 chain A Region: 216 - 376 Aligned: 155 Modelled: 158 Confidence: 99.6% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:complement factor b; PDBTitle: human complement factor b Phyre2 PDB 1jey chain B domain 2 Region: 217 - 343 Aligned: 127 Modelled: 127 Confidence: 99.5% Identity: 22% Fold: vWA-like Superfamily: vWA-like Family: Ku80 subunit N-terminal domain Phyre2 PDB 2ok5 chain A domain 1 Region: 211 - 376 Aligned: 161 Modelled: 165 Confidence: 99.5% Identity: 19% Fold: vWA-like Superfamily: vWA-like Family: Integrin A (or I) domain Phyre2 PDB 1yvr chain A domain 2 Region: 211 - 335 Aligned: 123 Modelled: 125 Confidence: 99.5% Identity: 20% Fold: vWA-like Superfamily: vWA-like Family: RoRNP C-terminal domain-like Phyre2 PDB 1yvr chain A Region: 99 - 335 Aligned: 222 Modelled: 225 Confidence: 99.5% Identity: 15% PDB header:rna binding protein Chain: A: PDB Molecule:60-kda ss-a/ro ribonucleoprotein; PDBTitle: ro autoantigen Phyre2 PDB 1jey chain A domain 2 Region: 217 - 342 Aligned: 126 Modelled: 126 Confidence: 99.5% Identity: 21% Fold: vWA-like Superfamily: vWA-like Family: Ku70 subunit N-terminal domain Phyre2 PDB 1shu chain X Region: 211 - 377 Aligned: 161 Modelled: 167 Confidence: 99.4% Identity: 18% Fold: vWA-like Superfamily: vWA-like Family: Integrin A (or I) domain Phyre2 PDB 2b2x chain B Region: 216 - 376 Aligned: 159 Modelled: 161 Confidence: 99.3% Identity: 15% PDB header:immune system Chain: B: PDB Molecule:integrin alpha-1; PDBTitle: vla1 rdeltah i-domain complexed with a quadruple mutant of the aqc22 fab Phyre2 PDB 2iue chain A Region: 214 - 313 Aligned: 100 Modelled: 100 Confidence: 99.3% Identity: 21% PDB header:membrane protein Chain: A: PDB Molecule:pactolus i-domain; PDBTitle: pactolus i-domain: functional switching of the rossmann2 fold Phyre2 PDB 2xgg chain B Region: 212 - 337 Aligned: 125 Modelled: 126 Confidence: 99.3% Identity: 19% PDB header:hydrolase Chain: B: PDB Molecule:microneme protein 2; PDBTitle: structure of toxoplasma gondii micronemal protein 2 a_i2 domain Phyre2 PDB 1pd0 chain A domain 3 Region: 212 - 361 Aligned: 145 Modelled: 150 Confidence: 99.3% Identity: 22% Fold: vWA-like Superfamily: vWA-like Family: Trunk domain of Sec23/24 Phyre2 PDB 3n2n chain C Region: 208 - 377 Aligned: 162 Modelled: 170 Confidence: 99.3% Identity: 18% PDB header:toxin receptor Chain: C: PDB Molecule:anthrax toxin receptor 1; PDBTitle: the crystal structure of tumor endothelial marker 8 (tem8)2 extracellular domain Phyre2 PDB 1u0o chain C domain 1 Region: 211 - 377 Aligned: 162 Modelled: 167 Confidence: 99.2% Identity: 15% Fold: vWA-like Superfamily: vWA-like Family: Integrin A (or I) domain Phyre2 PDB 1ijb chain A Region: 208 - 377 Aligned: 165 Modelled: 170 Confidence: 99.2% Identity: 13% Fold: vWA-like Superfamily: vWA-like Family: Integrin A (or I) domain Phyre2 1 c2nvoA_ 2 c3ibsA_ 3 c2x5nA_ 4 c2i6sA_ 5 c1rs0A_ 6 c2x31F_ 7 c2ok5A_ 8 d1jeyb2 9 d2ok5a1 10 d1yvra2 11 c1yvrA_ 12 d1jeya2 13 d1shux_ 14 c2b2xB_ 15 c2iueA_ 16 c2xggB_ 17 d1pd0a3 18 c3n2nC_ 19 d1u0oc1 20 d1ijba_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2nvoA_ 99.7 14 PDB header:rna binding protein Chain: A: PDB Molecule:ro sixty-related protein, rsr; PDBTitle: crystal structure of deinococcus radiodurans ro (rsr) protein 2 c3ibsA_ 99.7 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved hypothetical protein batb; PDBTitle: crystal structure of conserved hypothetical protein batb from2 bacteroides thetaiotaomicron 3 c2x5nA_ 99.6 11 PDB header:nuclear protein Chain: A: PDB Molecule:26s proteasome regulatory subunit rpn10; PDBTitle: crystal structure of the sprpn10 vwa domain 4 c2i6sA_ 99.6 18 PDB header:hydrolase Chain: A: PDB Molecule:complement c2a fragment; PDBTitle: complement component c2a 5 c1rs0A_ 99.6 19 PDB header:hydrolase Chain: A: PDB Molecule:complement factor b; PDBTitle: crystal structure analysis of the bb segment of factor b2 complexed with di-isopropyl-phosphate (dip) 6 c2x31F_ 99.6 19 PDB header:ligase Chain: F: PDB Molecule:magnesium-chelatase 60 kda subunit; PDBTitle: modelling of the complex between subunits bchi and bchd of magnesium2 chelatase based on single-particle cryo-em reconstruction at 7.5 ang 7 c2ok5A_ 99.6 19 PDB header:hydrolase Chain: A: PDB Molecule:complement factor b; PDBTitle: human complement factor b 8 d1jeyb2 99.5 22 Fold:vWA-like Superfamily:vWA-like Family:Ku80 subunit N-terminal domain 9 d2ok5a1 99.5 19 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 10 d1yvra2 99.5 20 Fold:vWA-like Superfamily:vWA-like Family:RoRNP C-terminal domain-like 11 c1yvrA_ 99.5 15 PDB header:rna binding protein Chain: A: PDB Molecule:60-kda ss-a/ro ribonucleoprotein; PDBTitle: ro autoantigen 12 d1jeya2 99.5 21 Fold:vWA-like Superfamily:vWA-like Family:Ku70 subunit N-terminal domain 13 d1shux_ 99.4 18 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 14 c2b2xB_ 99.3 15 PDB header:immune system Chain: B: PDB Molecule:integrin alpha-1; PDBTitle: vla1 rdeltah i-domain complexed with a quadruple mutant of the aqc22 fab 15 c2iueA_ 99.3 21 PDB header:membrane protein Chain: A: PDB Molecule:pactolus i-domain; PDBTitle: pactolus i-domain: functional switching of the rossmann2 fold 16 c2xggB_ 99.3 19 PDB header:hydrolase Chain: B: PDB Molecule:microneme protein 2; PDBTitle: structure of toxoplasma gondii micronemal protein 2 a_i2 domain 17 d1pd0a3 99.3 22 Fold:vWA-like Superfamily:vWA-like Family:Trunk domain of Sec23/24 18 c3n2nC_ 99.3 18 PDB header:toxin receptor Chain: C: PDB Molecule:anthrax toxin receptor 1; PDBTitle: the crystal structure of tumor endothelial marker 8 (tem8)2 extracellular domain 19 d1u0oc1 99.2 15 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 20 d1ijba_ 99.2 13 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 21 d1atza_ not modelled 99.1 16 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 22 c3gxbB_ not modelled 99.1 13 PDB header:cell adhesion Chain: B: PDB Molecule:von willebrand factor; PDBTitle: crystal structure of vwf a2 domain 23 c1jeyB_ not modelled 99.1 17 PDB header:dna binding protein/dna Chain: B: PDB Molecule:ku80; PDBTitle: crystal structure of the ku heterodimer bound to dna 24 d1v7pc_ not modelled 99.1 18 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 25 d1n3ya_ not modelled 99.1 14 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 26 d1ck4a_ not modelled 99.1 17 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 27 d1q0pa_ not modelled 99.1 21 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 28 d1pt6a_ not modelled 98.9 16 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 29 d1mf7a_ not modelled 98.9 13 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 30 d1tyeb2 not modelled 98.9 21 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 31 d1mjna_ not modelled 98.6 19 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 32 c3fcuB_ not modelled 98.6 21 PDB header:cell adhesion/blood clotting Chain: B: PDB Molecule:integrin beta-3; PDBTitle: structure of headpiece of integrin aiibb3 in open conformation 33 c3ragA_ not modelled 98.5 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of uncharacterized protein aaci_0196 from2 alicyclobacillus acidocaldarius subsp. acidocaldarius dsm 446 34 c1u8cB_ not modelled 98.4 22 PDB header:cell adhesion Chain: B: PDB Molecule:integrin beta-3; PDBTitle: a novel adaptation of the integrin psi domain revealed from its2 crystal structure 35 c1jeqA_ not modelled 98.2 18 PDB header:dna binding protein Chain: A: PDB Molecule:ku70; PDBTitle: crystal structure of the ku heterodimer 36 c1pd0A_ not modelled 98.0 23 PDB header:transport protein Chain: A: PDB Molecule:protein transport protein sec24; PDBTitle: crystal structure of the copii coat subunit, sec24,2 complexed with a peptide from the snare protein sed53 (yeast syntaxin-5) 37 c3k6sB_ not modelled 97.8 19 PDB header:cell adhesion Chain: B: PDB Molecule:integrin beta-2; PDBTitle: structure of integrin alphaxbeta2 ectodomain 38 c1m2vB_ not modelled 97.6 26 PDB header:protein transport Chain: B: PDB Molecule:protein transport protein sec24; PDBTitle: crystal structure of the yeast sec23/24 heterodimer 39 c3eh2B_ not modelled 97.6 17 PDB header:protein transport Chain: B: PDB Molecule:protein transport protein sec24c; PDBTitle: crystal structure of the human copii-coat protein sec24c 40 c3egxB_ not modelled 97.5 18 PDB header:protein transport Chain: B: PDB Molecule:protein transport protein sec24a; PDBTitle: crystal structure of the mammalian copii-coat protein2 sec23a/24a complexed with the snare protein sec22b and3 bound to the transport signal sequence of the snare protein4 bet1 41 c3eg9A_ not modelled 97.5 19 PDB header:protein transport Chain: A: PDB Molecule:protein transport protein sec23a; PDBTitle: crystal structure of the mammalian copii-coat protein2 sec23/24 bound to the transport signal sequence of membrin 42 d2qtva3 not modelled 97.4 19 Fold:vWA-like Superfamily:vWA-like Family:Trunk domain of Sec23/24 43 c3eg9B_ not modelled 97.3 16 PDB header:protein transport Chain: B: PDB Molecule:sec24 related gene family, member d; PDBTitle: crystal structure of the mammalian copii-coat protein2 sec23/24 bound to the transport signal sequence of membrin 44 c1m2oA_ not modelled 97.0 18 PDB header:protein transport/signaling protein Chain: A: PDB Molecule:protein transport protein sec23; PDBTitle: crystal structure of the sec23-sar1 complex 45 c3eyaE_ not modelled 84.0 13 PDB header:oxidoreductase Chain: E: PDB Molecule:pyruvate dehydrogenase [cytochrome]; PDBTitle: structural basis for membrane binding and catalytic2 activation of the peripheral membrane enzyme pyruvate3 oxidase from escherichia coli 46 d2djia3 not modelled 77.6 14 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 47 d1jsca3 not modelled 73.7 18 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 48 c1jscA_ not modelled 67.6 18 PDB header:lyase Chain: A: PDB Molecule:acetohydroxy-acid synthase; PDBTitle: crystal structure of the catalytic subunit of yeast2 acetohydroxyacid synthase: a target for herbicidal3 inhibitors 49 d1twda_ not modelled 64.0 19 Fold:TIM beta/alpha-barrel Superfamily:CutC-like Family:CutC-like 50 d2ji7a3 not modelled 63.6 18 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 51 d2piaa2 not modelled 61.7 13 Fold:Ferredoxin reductase-like, C-terminal NADP-linked domain Superfamily:Ferredoxin reductase-like, C-terminal NADP-linked domain Family:Aromatic dioxygenase reductase-like 52 d1li4a2 not modelled 56.9 21 Fold:Flavodoxin-like Superfamily:Formate/glycerate dehydrogenase catalytic domain-like Family:S-adenosylhomocystein hydrolase 53 d1t9ba3 not modelled 54.3 18 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 54 d1dkua2 not modelled 54.1 18 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 55 d1ozha3 not modelled 51.7 17 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 56 c3iwpK_ not modelled 51.1 16 PDB header:metal binding protein Chain: K: PDB Molecule:copper homeostasis protein cutc homolog; PDBTitle: crystal structure of human copper homeostasis protein cutc 57 d1ybha3 not modelled 49.9 16 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 58 d1wd5a_ not modelled 46.4 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 59 c2bdqA_ not modelled 46.2 17 PDB header:metal transport Chain: A: PDB Molecule:copper homeostasis protein cutc; PDBTitle: crystal structure of the putative copper homeostasis2 protein cutc from streptococcus agalactiae, northeast3 strucural genomics target sar15. 60 d1y0ba1 not modelled 44.7 16 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 61 c3d64A_ not modelled 44.3 19 PDB header:hydrolase Chain: A: PDB Molecule:adenosylhomocysteinase; PDBTitle: crystal structure of s-adenosyl-l-homocysteine hydrolase from2 burkholderia pseudomallei 62 c3oneA_ not modelled 42.3 17 PDB header:hydrolase/hydrolase substrate Chain: A: PDB Molecule:adenosylhomocysteinase; PDBTitle: crystal structure of lupinus luteus s-adenosyl-l-homocysteine2 hydrolase in complex with adenine 63 c2yzkC_ not modelled 40.2 17 PDB header:transferase Chain: C: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: crystal structure of orotate phosphoribosyltransferase from2 aeropyrum pernix 64 d2ez9a3 not modelled 39.6 13 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 65 c2vf7B_ not modelled 38.6 20 PDB header:dna-binding protein Chain: B: PDB Molecule:excinuclease abc, subunit a.; PDBTitle: crystal structure of uvra2 from deinococcus radiodurans 66 c2wnsB_ not modelled 37.1 19 PDB header:transferase Chain: B: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: human orotate phosphoribosyltransferase (oprtase) domain of2 uridine 5'-monophosphate synthase (umps) in complex with3 its substrate orotidine 5'-monophosphate (omp) 67 d2aeea1 not modelled 37.1 16 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 68 c2djiA_ not modelled 36.9 14 PDB header:oxidoreductase Chain: A: PDB Molecule:pyruvate oxidase; PDBTitle: crystal structure of pyruvate oxidase from aerococcus2 viridans containing fad 69 c1d4fD_ not modelled 36.7 17 PDB header:hydrolase Chain: D: PDB Molecule:s-adenosylhomocysteine hydrolase; PDBTitle: crystal structure of recombinant rat-liver d244e mutant s-2 adenosylhomocysteine hydrolase 70 c3m3hA_ not modelled 34.9 19 PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: 1.75 angstrom resolution crystal structure of an orotate2 phosphoribosyltransferase from bacillus anthracis str. 'ames3 ancestor' 71 d2r8oa2 not modelled 34.2 14 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:TK-like PP module 72 c3pihA_ not modelled 33.7 16 PDB header:hydrolase/dna Chain: A: PDB Molecule:uvrabc system protein a; PDBTitle: t. maritima uvra in complex with fluorescein-modified dna 73 c2jlaD_ not modelled 32.2 12 PDB header:transferase Chain: D: PDB Molecule:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene PDBTitle: crystal structure of e.coli mend, 2-succinyl-5-enolpyruvyl-2 6-hydroxy-3-cyclohexadiene-1-carboxylate synthase - semet3 protein 74 d1l1qa_ not modelled 31.3 13 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 75 c2pgnA_ not modelled 31.3 13 PDB header:hydrolase Chain: A: PDB Molecule:cyclohexane-1,2-dione hydrolase (cdh); PDBTitle: the crystal structure of fad and thdp-dependent cyclohexane-1,2-dione2 hydrolase in complex with cyclohexane-1,2-dione 76 c2ji6B_ not modelled 30.4 20 PDB header:lyase Chain: B: PDB Molecule:oxalyl-coa decarboxylase; PDBTitle: x-ray structure of oxalyl-coa decarboxylase in complex with2 3-deaza-thdp and oxalyl-coa 77 c1sy7B_ not modelled 29.4 14 PDB header:oxidoreductase Chain: B: PDB Molecule:catalase 1; PDBTitle: crystal structure of the catalase-1 from neurospora crassa, native2 structure at 1.75a resolution. 78 c1upaC_ not modelled 29.2 13 PDB header:synthase Chain: C: PDB Molecule:carboxyethylarginine synthase; PDBTitle: carboxyethylarginine synthase from streptomyces2 clavuligerus (semet structure) 79 c3n58D_ not modelled 28.9 19 PDB header:hydrolase Chain: D: PDB Molecule:adenosylhomocysteinase; PDBTitle: crystal structure of s-adenosyl-l-homocysteine hydrolase from brucella2 melitensis in ternary complex with nad and adenosine, orthorhombic3 form 80 c3gvpB_ not modelled 28.6 17 PDB header:hydrolase Chain: B: PDB Molecule:adenosylhomocysteinase 3; PDBTitle: human sahh-like domain of human adenosylhomocysteinase 3 81 c1ozhD_ not modelled 28.4 17 PDB header:lyase Chain: D: PDB Molecule:acetolactate synthase, catabolic; PDBTitle: the crystal structure of klebsiella pneumoniae acetolactate2 synthase with enzyme-bound cofactor and with an unusual3 intermediate. 82 d1pvda3 not modelled 26.7 13 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 83 c1j9zB_ not modelled 26.0 12 PDB header:oxidoreductase Chain: B: PDB Molecule:nadph-cytochrome p450 reductase; PDBTitle: cypor-w677g 84 c1t9dB_ not modelled 25.9 18 PDB header:transferase Chain: B: PDB Molecule:acetolactate synthase, mitochondrial; PDBTitle: crystal structure of yeast acetohydroxyacid synthase in2 complex with a sulfonylurea herbicide, metsulfuron methyl 85 c2hgsA_ not modelled 25.4 13 PDB header:amine/carboxylate ligase Chain: A: PDB Molecule:protein (glutathione synthetase); PDBTitle: human glutathione synthetase 86 d1q6za3 not modelled 25.2 20 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 87 c3gbcA_ not modelled 24.6 10 PDB header:hydrolase Chain: A: PDB Molecule:pyrazinamidase/nicotinamidas pnca; PDBTitle: determination of the crystal structure of the pyrazinamidase from2 m.tuberculosis : a structure-function analysis for prediction3 resistance to pyrazinamide 88 c1yi1A_ not modelled 24.5 14 PDB header:transferase Chain: A: PDB Molecule:acetolactate synthase; PDBTitle: crystal structure of arabidopsis thaliana acetohydroxyacid synthase in2 complex with a sulfonylurea herbicide, tribenuron methyl 89 d1chda_ not modelled 24.4 8 Fold:Methylesterase CheB, C-terminal domain Superfamily:Methylesterase CheB, C-terminal domain Family:Methylesterase CheB, C-terminal domain 90 d1v8ba2 not modelled 23.6 15 Fold:Flavodoxin-like Superfamily:Formate/glycerate dehydrogenase catalytic domain-like Family:S-adenosylhomocystein hydrolase 91 c3efhB_ not modelled 23.2 19 PDB header:transferase Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase 1; PDBTitle: crystal structure of human phosphoribosyl pyrophosphate2 synthetase 1 92 d1itza1 not modelled 22.7 11 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:TK-like PP module 93 c2panF_ not modelled 22.4 15 PDB header:lyase Chain: F: PDB Molecule:glyoxylate carboligase; PDBTitle: crystal structure of e. coli glyoxylate carboligase 94 c4a2iV_ not modelled 22.2 12 PDB header:ribosome/hydrolase Chain: V: PDB Molecule:putative ribosome biogenesis gtpase rsga; PDBTitle: cryo-electron microscopy structure of the 30s subunit in complex with2 the yjeq biogenesis factor 95 c2bpoA_ not modelled 21.7 13 PDB header:reductase Chain: A: PDB Molecule:nadph-cytochrom p450 reductase; PDBTitle: crystal structure of the yeast cpr triple mutant: d74g,2 y75f, k78a. 96 c2c4kD_ not modelled 21.4 11 PDB header:regulatory protein Chain: D: PDB Molecule:phosphoribosyl pyrophosphate synthetase- PDBTitle: crystal structure of human phosphoribosylpyrophosphate2 synthetase-associated protein 39 (pap39) 97 c1cqxB_ not modelled 21.3 11 PDB header:lipid binding protein Chain: B: PDB Molecule:flavohemoprotein; PDBTitle: crystal structure of the flavohemoglobin from alcaligenes eutrophus at2 1.75 a resolution 98 c3sftA_ not modelled 21.2 11 PDB header:hydrolase Chain: A: PDB Molecule:chemotaxis response regulator protein-glutamate PDBTitle: crystal structure of thermotoga maritima cheb methylesterase catalytic2 domain 99 c2x7jA_ not modelled 21.2 16 PDB header:transferase Chain: A: PDB Molecule:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene PDBTitle: structure of the menaquinone biosynthesis protein mend from2 bacillus subtilis 100 c3cueM_ not modelled 21.2 6 PDB header:protein transport Chain: M: PDB Molecule:transport protein particle 23 kda subunit; PDBTitle: crystal structure of a trapp subassembly activating the rab2 ypt1p 101 c2dy0A_ not modelled 20.8 20 PDB header:transferase Chain: A: PDB Molecule:adenine phosphoribosyltransferase; PDBTitle: crystal structure of project jw0458 from escherichia coli 102 d1gpua1 not modelled 20.3 15 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:TK-like PP module 103 c1tllA_ not modelled 20.1 14 PDB header:oxidoreductase Chain: A: PDB Molecule:nitric-oxide synthase, brain; PDBTitle: crystal structure of rat neuronal nitric-oxide synthase2 reductase module at 2.3 a resolution.

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0