Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP17169
DateThu Jan 5 11:36:02 GMT 2012
Unique Job ID3fcf1025d3b1f7e2

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1jxaA_
Top template information
PDB header:transferase
Chain: A: PDB Molecule:glucosamine 6-phosphate synthase;
PDBTitle: glucosamine 6-phosphate synthase with glucose 6-phosphate
Confidence and coverage
Confidence:100.0% Coverage:100%
608 residues (100% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MCGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMTRLRRLGKVQMLAQAAE
Secondary structure 
SS confidence 
Disorder  ??
?????
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  EHPLHGGTGIAHTRWATHGEPSEVNAHPHVSEHIVVVHNGIIENHEPLREELKARGYTFV
Secondary structure 
SS confidence 
Disorder  ?????
?
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  SETDTEVIAHLVNWELKQGGTLREAVLRAIPQLRGAYGTVIMDSRHPDTLLAARSGSPLV
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  IGLGMGENFIASDQLALLPVTRRFIFLEEGDIAEITRRSVNIFDKTGAEVKRQDIESNLQ
Secondary structure 
SS confidence 
Disorder 
?
?
??
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  YDAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILA
Secondary structure 
SS confidence 
Disorder  ??
?
?
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  CGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGL
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  RLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKL
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........430.........440.........450.........460.........470.........480
Sequence  SRLKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQYPIA
Secondary structure 
SS confidence 
Disorder 
??????
Disorder confidence 
 
   .........490.........500.........510.........520.........530.........540
Sequence  LEGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRAR
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........550.........560.........570.........580.........590.........600
Sequence  GGQLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPR
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........
Sequence  NLAKSVTVE
Secondary structure 
SS confidence 
Disorder 
??
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1jxa chain A

3D model

Region: 2 - 609
Aligned: 608
Modelled: 608
Confidence: 100.0%
Identity: 100%
PDB header:transferase
Chain: A: PDB Molecule:glucosamine 6-phosphate synthase;
PDBTitle: glucosamine 6-phosphate synthase with glucose 6-phosphate

Phyre2

PDB 1moq chain A

3D model

Region: 245 - 609
Aligned: 365
Modelled: 365
Confidence: 100.0%
Identity: 100%
Fold: SIS domain
Superfamily: SIS domain
Family: double-SIS domain

Phyre2

PDB 2zj3 chain A

3D model

Region: 246 - 609
Aligned: 363
Modelled: 364
Confidence: 100.0%
Identity: 42%
PDB header:transferase
Chain: A: PDB Molecule:glucosamine--fructose-6-phosphate
PDBTitle: isomerase domain of human glucose:fructose-6-phosphate2 amidotransferase

Phyre2

PDB 3tbf chain A

3D model

Region: 245 - 599
Aligned: 355
Modelled: 355
Confidence: 100.0%
Identity: 54%
PDB header:transferase
Chain: A: PDB Molecule:glucosamine--fructose-6-phosphate aminotransferase
PDBTitle: c-terminal domain of glucosamine-fructose-6-phosphate aminotransferase2 from francisella tularensis.

Phyre2

PDB 3odp chain A

3D model

Region: 241 - 606
Aligned: 351
Modelled: 365
Confidence: 100.0%
Identity: 18%
PDB header:isomerase
Chain: A: PDB Molecule:putative tagatose-6-phosphate ketose/aldose isomerase;
PDBTitle: crystal structure of a putative tagatose-6-phosphate ketose/aldose2 isomerase (nt01cx_0292) from clostridium novyi nt at 2.35 a3 resolution

Phyre2

PDB 3i0z chain B

3D model

Region: 237 - 606
Aligned: 356
Modelled: 370
Confidence: 100.0%
Identity: 19%
PDB header:isomerase
Chain: B: PDB Molecule:putative tagatose-6-phosphate ketose/aldose isomerase;
PDBTitle: crystal structure of putative putative tagatose-6-phosphate2 ketose/aldose isomerase (np_344614.1) from streptococcus pneumoniae3 tigr4 at 1.70 a resolution

Phyre2

PDB 2aml chain B

3D model

Region: 253 - 601
Aligned: 336
Modelled: 340
Confidence: 100.0%
Identity: 19%
PDB header:transferase
Chain: B: PDB Molecule:sis domain protein;
PDBTitle: crystal structure of lmo0035 protein (46906266) from listeria2 monocytogenes 4b f2365 at 1.50 a resolution

Phyre2

PDB 2puw chain A

3D model

Region: 248 - 597
Aligned: 338
Modelled: 350
Confidence: 100.0%
Identity: 40%
PDB header:transferase
Chain: A: PDB Molecule:isomerase domain of glutamine-fructose-6-phosphate
PDBTitle: the crystal structure of isomerase domain of glucosamine-6-phosphate2 synthase from candida albicans

Phyre2

PDB 3c3j chain A

3D model

Region: 238 - 608
Aligned: 355
Modelled: 371
Confidence: 100.0%
Identity: 19%
PDB header:isomerase
Chain: A: PDB Molecule:putative tagatose-6-phosphate ketose/aldose isomerase;
PDBTitle: crystal structure of tagatose-6-phosphate ketose/aldose isomerase from2 escherichia coli

Phyre2

PDB 3g68 chain A

3D model

Region: 251 - 608
Aligned: 341
Modelled: 357
Confidence: 100.0%
Identity: 20%
PDB header:isomerase
Chain: A: PDB Molecule:putative phosphosugar isomerase;
PDBTitle: crystal structure of a putative phosphosugar isomerase (cd3275) from2 clostridium difficile 630 at 1.80 a resolution

Phyre2

PDB 3fj1 chain A

3D model

Region: 246 - 597
Aligned: 330
Modelled: 351
Confidence: 100.0%
Identity: 24%
PDB header:isomerase
Chain: A: PDB Molecule:putative phosphosugar isomerase;
PDBTitle: crystal structure of putative phosphosugar isomerase (yp_167080.1)2 from silicibacter pomeroyi dss-3 at 1.75 a resolution

Phyre2

PDB 1j5x chain A

3D model

Region: 253 - 608
Aligned: 316
Modelled: 342
Confidence: 100.0%
Identity: 27%
Fold: SIS domain
Superfamily: SIS domain
Family: double-SIS domain

Phyre2

PDB 2dec chain A

3D model

Region: 253 - 606
Aligned: 320
Modelled: 341
Confidence: 100.0%
Identity: 27%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:325aa long hypothetical protein;
PDBTitle: crystal structure of the ph0510 protein from pyrococcus horikoshii ot3

Phyre2

PDB 3fkj chain A

3D model

Region: 271 - 605
Aligned: 324
Modelled: 332
Confidence: 100.0%
Identity: 18%
PDB header:isomerase
Chain: A: PDB Molecule:putative phosphosugar isomerases;
PDBTitle: crystal structure of a putative phosphosugar isomerase (stm_0572) from2 salmonella typhimurium lt2 at 2.12 a resolution

Phyre2

PDB 2a3n chain A

3D model

Region: 251 - 605
Aligned: 328
Modelled: 355
Confidence: 100.0%
Identity: 18%
PDB header:sugar binding protein
Chain: A: PDB Molecule:putative glucosamine-fructose-6-phosphate aminotransferase;
PDBTitle: crystal structure of a putative glucosamine-fructose-6-phosphate2 aminotransferase (stm4540.s) from salmonella typhimurium lt2 at 1.353 a resolution

Phyre2

PDB 3eua chain D

3D model

Region: 276 - 607
Aligned: 315
Modelled: 332
Confidence: 100.0%
Identity: 23%
PDB header:isomerase
Chain: D: PDB Molecule:putative fructose-aminoacid-6-phosphate deglycase;
PDBTitle: crystal structure of a putative phosphosugar isomerase (bsu32610) from2 bacillus subtilis at 1.90 a resolution

Phyre2

PDB 3hba chain A

3D model

Region: 250 - 598
Aligned: 307
Modelled: 324
Confidence: 100.0%
Identity: 29%
PDB header:isomerase
Chain: A: PDB Molecule:putative phosphosugar isomerase;
PDBTitle: crystal structure of a putative phosphosugar isomerase (sden_2705)2 from shewanella denitrificans os217 at 2.00 a resolution

Phyre2

PDB 3knz chain A

3D model

Region: 253 - 588
Aligned: 316
Modelled: 336
Confidence: 100.0%
Identity: 20%
PDB header:sugar binding protein
Chain: A: PDB Molecule:putative sugar binding protein;
PDBTitle: crystal structure of putative sugar binding protein (np_459565.1) from2 salmonella typhimurium lt2 at 2.50 a resolution

Phyre2

PDB 1xff chain A

3D model

Region: 2 - 240
Aligned: 239
Modelled: 238
Confidence: 100.0%
Identity: 100%
Fold: Ntn hydrolase-like
Superfamily: N-terminal nucleophile aminohydrolases (Ntn hydrolases)
Family: Class II glutamine amidotransferases

Phyre2

PDB 1gph chain 1

3D model

Region: 2 - 234
Aligned: 227
Modelled: 232
Confidence: 100.0%
Identity: 27%
PDB header:transferase(glutamine amidotransferase)
Chain: 1: PDB Molecule:glutamine phosphoribosyl-pyrophosphate amidotransferase;
PDBTitle: structure of the allosteric regulatory enzyme of purine biosynthesis

Phyre2
1
c1jxaA_
2
d1moqa_
3
c2zj3A_
4
c3tbfA_
5
c3odpA_
6
c3i0zB_
7
c2amlB_
8
c2puwA_
9
c3c3jA_
10
c3g68A_
11
c3fj1A_
12
d1j5xa_
13
c2decA_
14
c3fkjA_
15
c2a3nA_
16
c3euaD_
17
c3hbaA_
18
c3knzA_
19
d1xffa_
20
c1gph1_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1jxaA_
100.0 100 PDB header:transferase
Chain: A: PDB Molecule:glucosamine 6-phosphate synthase;
PDBTitle: glucosamine 6-phosphate synthase with glucose 6-phosphate
2d1moqa_
100.0 100 Fold:SIS domain
Superfamily:SIS domain
Family:double-SIS domain
3c2zj3A_
100.0 42 PDB header:transferase
Chain: A: PDB Molecule:glucosamine--fructose-6-phosphate
PDBTitle: isomerase domain of human glucose:fructose-6-phosphate2 amidotransferase
4c3tbfA_
100.0 54 PDB header:transferase
Chain: A: PDB Molecule:glucosamine--fructose-6-phosphate aminotransferase
PDBTitle: c-terminal domain of glucosamine-fructose-6-phosphate aminotransferase2 from francisella tularensis.
5c3odpA_
100.0 18 PDB header:isomerase
Chain: A: PDB Molecule:putative tagatose-6-phosphate ketose/aldose isomerase;
PDBTitle: crystal structure of a putative tagatose-6-phosphate ketose/aldose2 isomerase (nt01cx_0292) from clostridium novyi nt at 2.35 a3 resolution
6c3i0zB_
100.0 19 PDB header:isomerase
Chain: B: PDB Molecule:putative tagatose-6-phosphate ketose/aldose isomerase;
PDBTitle: crystal structure of putative putative tagatose-6-phosphate2 ketose/aldose isomerase (np_344614.1) from streptococcus pneumoniae3 tigr4 at 1.70 a resolution
7c2amlB_
100.0 19 PDB header:transferase
Chain: B: PDB Molecule:sis domain protein;
PDBTitle: crystal structure of lmo0035 protein (46906266) from listeria2 monocytogenes 4b f2365 at 1.50 a resolution
8c2puwA_
100.0 40 PDB header:transferase
Chain: A: PDB Molecule:isomerase domain of glutamine-fructose-6-phosphate
PDBTitle: the crystal structure of isomerase domain of glucosamine-6-phosphate2 synthase from candida albicans
9c3c3jA_
100.0 19 PDB header:isomerase
Chain: A: PDB Molecule:putative tagatose-6-phosphate ketose/aldose isomerase;
PDBTitle: crystal structure of tagatose-6-phosphate ketose/aldose isomerase from2 escherichia coli
10c3g68A_
100.0 20 PDB header:isomerase
Chain: A: PDB Molecule:putative phosphosugar isomerase;
PDBTitle: crystal structure of a putative phosphosugar isomerase (cd3275) from2 clostridium difficile 630 at 1.80 a resolution
11c3fj1A_
100.0 24 PDB header:isomerase
Chain: A: PDB Molecule:putative phosphosugar isomerase;
PDBTitle: crystal structure of putative phosphosugar isomerase (yp_167080.1)2 from silicibacter pomeroyi dss-3 at 1.75 a resolution
12d1j5xa_
100.0 27 Fold:SIS domain
Superfamily:SIS domain
Family:double-SIS domain
13c2decA_
100.0 27 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:325aa long hypothetical protein;
PDBTitle: crystal structure of the ph0510 protein from pyrococcus horikoshii ot3
14c3fkjA_
100.0 18 PDB header:isomerase
Chain: A: PDB Molecule:putative phosphosugar isomerases;
PDBTitle: crystal structure of a putative phosphosugar isomerase (stm_0572) from2 salmonella typhimurium lt2 at 2.12 a resolution
15c2a3nA_
100.0 18 PDB header:sugar binding protein
Chain: A: PDB Molecule:putative glucosamine-fructose-6-phosphate aminotransferase;
PDBTitle: crystal structure of a putative glucosamine-fructose-6-phosphate2 aminotransferase (stm4540.s) from salmonella typhimurium lt2 at 1.353 a resolution
16c3euaD_
100.0 23 PDB header:isomerase
Chain: D: PDB Molecule:putative fructose-aminoacid-6-phosphate deglycase;
PDBTitle: crystal structure of a putative phosphosugar isomerase (bsu32610) from2 bacillus subtilis at 1.90 a resolution
17c3hbaA_
100.0 29 PDB header:isomerase
Chain: A: PDB Molecule:putative phosphosugar isomerase;
PDBTitle: crystal structure of a putative phosphosugar isomerase (sden_2705)2 from shewanella denitrificans os217 at 2.00 a resolution
18c3knzA_
100.0 20 PDB header:sugar binding protein
Chain: A: PDB Molecule:putative sugar binding protein;
PDBTitle: crystal structure of putative sugar binding protein (np_459565.1) from2 salmonella typhimurium lt2 at 2.50 a resolution
19d1xffa_
100.0 100 Fold:Ntn hydrolase-like
Superfamily:N-terminal nucleophile aminohydrolases (Ntn hydrolases)
Family:Class II glutamine amidotransferases
20c1gph1_
100.0 27 PDB header:transferase(glutamine amidotransferase)
Chain: 1: PDB Molecule:glutamine phosphoribosyl-pyrophosphate amidotransferase;
PDBTitle: structure of the allosteric regulatory enzyme of purine biosynthesis
21c1ecjB_
not modelled 100.0 21 PDB header:transferase
Chain: B: PDB Molecule:glutamine phosphoribosylpyrophosphate
PDBTitle: escherichia coli glutamine phosphoribosylpyrophosphate2 (prpp) amidotransferase complexed with 2 amp per tetramer
22d1ecfa2
not modelled 100.0 29 Fold:Ntn hydrolase-like
Superfamily:N-terminal nucleophile aminohydrolases (Ntn hydrolases)
Family:Class II glutamine amidotransferases
23d1gph12
not modelled 100.0 28 Fold:Ntn hydrolase-like
Superfamily:N-terminal nucleophile aminohydrolases (Ntn hydrolases)
Family:Class II glutamine amidotransferases
24d1x9ia_
not modelled 100.0 14 Fold:SIS domain
Superfamily:SIS domain
Family:double-SIS domain
25c1ct9D_
not modelled 100.0 29 PDB header:ligase
Chain: D: PDB Molecule:asparagine synthetase b;
PDBTitle: crystal structure of asparagine synthetase b from2 escherichia coli
26d1ct9a2
not modelled 100.0 29 Fold:Ntn hydrolase-like
Superfamily:N-terminal nucleophile aminohydrolases (Ntn hydrolases)
Family:Class II glutamine amidotransferases
27d1ofda3
not modelled 100.0 22 Fold:Ntn hydrolase-like
Superfamily:N-terminal nucleophile aminohydrolases (Ntn hydrolases)
Family:Class II glutamine amidotransferases
28d1ea0a3
not modelled 100.0 23 Fold:Ntn hydrolase-like
Superfamily:N-terminal nucleophile aminohydrolases (Ntn hydrolases)
Family:Class II glutamine amidotransferases
29d1te5a_
not modelled 100.0 23 Fold:Ntn hydrolase-like
Superfamily:N-terminal nucleophile aminohydrolases (Ntn hydrolases)
Family:Class II glutamine amidotransferases
30c3mdnD_
not modelled 99.9 24 PDB header:transferase
Chain: D: PDB Molecule:glutamine aminotransferase class-ii domain protein;
PDBTitle: structure of glutamine aminotransferase class-ii domain protein2 (spo2029) from silicibacter pomeroyi
31c1m1zB_
not modelled 99.9 21 PDB header:hydrolase
Chain: B: PDB Molecule:beta-lactam synthetase;
PDBTitle: beta-lactam synthetase apo enzyme
32c1q15A_
not modelled 99.9 13 PDB header:biosynthetic protein
Chain: A: PDB Molecule:cara;
PDBTitle: carbapenam synthetase
33d1jgta2
not modelled 99.9 21 Fold:Ntn hydrolase-like
Superfamily:N-terminal nucleophile aminohydrolases (Ntn hydrolases)
Family:Class II glutamine amidotransferases
34d1q15a2
not modelled 99.9 17 Fold:Ntn hydrolase-like
Superfamily:N-terminal nucleophile aminohydrolases (Ntn hydrolases)
Family:Class II glutamine amidotransferases
35c2xhzC_
not modelled 99.9 20 PDB header:isomerase
Chain: C: PDB Molecule:arabinose 5-phosphate isomerase;
PDBTitle: probing the active site of the sugar isomerase domain from e. coli2 arabinose-5-phosphate isomerase via x-ray crystallography
36c3etnD_
not modelled 99.9 22 PDB header:isomerase
Chain: D: PDB Molecule:putative phosphosugar isomerase involved in capsule
PDBTitle: crystal structure of putative phosphosugar isomerase involved in2 capsule formation (yp_209877.1) from bacteroides fragilis nctc 93433 at 1.70 a resolution
37c1nriA_
not modelled 99.8 24 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein hi0754;
PDBTitle: crystal structure of putative phosphosugar isomerase hi0754 from2 haemophilus influenzae
38d1nria_
not modelled 99.8 24 Fold:SIS domain
Superfamily:SIS domain
Family:mono-SIS domain
39d1vima_
not modelled 99.8 19 Fold:SIS domain
Superfamily:SIS domain
Family:mono-SIS domain
40c3fxaA_
not modelled 99.8 16 PDB header:sugar binding protein
Chain: A: PDB Molecule:sis domain protein;
PDBTitle: crystal structure of a putative sugar-phosphate isomerase2 (lmof2365_0531) from listeria monocytogenes str. 4b f2365 at 1.60 a3 resolution
41c3shoA_
not modelled 99.8 18 PDB header:transcription regulator
Chain: A: PDB Molecule:transcriptional regulator, rpir family;
PDBTitle: crystal structure of rpir transcription factor from sphaerobacter2 thermophilus (sugar isomerase domain)
42d1x94a_
not modelled 99.8 13 Fold:SIS domain
Superfamily:SIS domain
Family:mono-SIS domain
43c2x3yA_
not modelled 99.7 15 PDB header:isomerase
Chain: A: PDB Molecule:phosphoheptose isomerase;
PDBTitle: crystal structure of gmha from burkholderia pseudomallei
44c1lm1A_
not modelled 99.7 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:ferredoxin-dependent glutamate synthase;
PDBTitle: structural studies on the synchronization of catalytic centers in2 glutamate synthase: native enzyme
45d1tk9a_
not modelled 99.7 17 Fold:SIS domain
Superfamily:SIS domain
Family:mono-SIS domain
46c2vdcF_
not modelled 99.7 24 PDB header:oxidoreductase
Chain: F: PDB Molecule:glutamate synthase [nadph] large chain;
PDBTitle: the 9.5 a resolution structure of glutamate synthase from2 cryo-electron microscopy and its oligomerization behavior3 in solution: functional implications.
47d1m3sa_
not modelled 99.7 19 Fold:SIS domain
Superfamily:SIS domain
Family:mono-SIS domain
48c3cvjB_
not modelled 99.7 17 PDB header:isomerase
Chain: B: PDB Molecule:putative phosphoheptose isomerase;
PDBTitle: crystal structure of a putative phosphoheptose isomerase (bh3325) from2 bacillus halodurans c-125 at 2.00 a resolution
49d1x92a_
not modelled 99.7 15 Fold:SIS domain
Superfamily:SIS domain
Family:mono-SIS domain
50d1jeoa_
not modelled 99.6 20 Fold:SIS domain
Superfamily:SIS domain
Family:mono-SIS domain
51c3trjC_
not modelled 99.6 10 PDB header:isomerase
Chain: C: PDB Molecule:phosphoheptose isomerase;
PDBTitle: structure of a phosphoheptose isomerase from francisella tularensis
52c2yvaB_
not modelled 99.6 13 PDB header:dna binding protein
Chain: B: PDB Molecule:dnaa initiator-associating protein diaa;
PDBTitle: crystal structure of escherichia coli diaa
53d1wiwa_
not modelled 99.0 15 Fold:SIS domain
Superfamily:SIS domain
Family:double-SIS domain
54c2q8nB_
not modelled 98.4 15 PDB header:isomerase
Chain: B: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: crystal structure of glucose-6-phosphate isomerase (ec2 5.3.1.9) (tm1385) from thermotoga maritima at 1.82 a3 resolution
55c3ff1B_
not modelled 98.3 16 PDB header:isomerase
Chain: B: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: structure of glucose 6-phosphate isomerase from staphylococcus aureus
56d1c7qa_
not modelled 98.3 15 Fold:SIS domain
Superfamily:SIS domain
Family:Phosphoglucose isomerase, PGI
57d1gzda_
not modelled 98.2 13 Fold:SIS domain
Superfamily:SIS domain
Family:Phosphoglucose isomerase, PGI
58d1q50a_
not modelled 98.2 13 Fold:SIS domain
Superfamily:SIS domain
Family:Phosphoglucose isomerase, PGI
59c1zzgB_
not modelled 98.2 23 PDB header:isomerase
Chain: B: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: crystal structure of hypothetical protein tt0462 from thermus2 thermophilus hb8
60c1t10A_
not modelled 98.1 13 PDB header:isomerase
Chain: A: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: phosphoglucose isomerase from leishmania mexicana in complex with2 substrate d-fructose-6-phosphate
61c3hjbA_
not modelled 98.1 11 PDB header:isomerase
Chain: A: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: 1.5 angstrom crystal structure of glucose-6-phosphate isomerase from2 vibrio cholerae.
62c2wu8A_
not modelled 98.1 11 PDB header:isomerase
Chain: A: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: structural studies of phosphoglucose isomerase from2 mycobacterium tuberculosis h37rv
63d1hm5a_
not modelled 98.0 12 Fold:SIS domain
Superfamily:SIS domain
Family:Phosphoglucose isomerase, PGI
64d1iata_
not modelled 98.0 14 Fold:SIS domain
Superfamily:SIS domain
Family:Phosphoglucose isomerase, PGI
65d1u0fa_
not modelled 98.0 14 Fold:SIS domain
Superfamily:SIS domain
Family:Phosphoglucose isomerase, PGI
66c3ljkA_
not modelled 98.0 14 PDB header:isomerase
Chain: A: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: glucose-6-phosphate isomerase from francisella tularensis.
67c3pr3B_
not modelled 98.0 13 PDB header:isomerase
Chain: B: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: crystal structure of plasmodium falciparum glucose-6-phosphate2 isomerase (pf14_0341) in complex with fructose-6-phosphate
68c3nbuC_
not modelled 98.0 12 PDB header:isomerase
Chain: C: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: crystal structure of pgi glucosephosphate isomerase
69c2o2cB_
not modelled 97.9 10 PDB header:isomerase
Chain: B: PDB Molecule:glucose-6-phosphate isomerase, glycosomal;
PDBTitle: crystal structure of phosphoglucose isomerase from t. brucei2 containing glucose-6-phosphate in the active site
70c3ujhB_
not modelled 97.9 14 PDB header:isomerase
Chain: B: PDB Molecule:glucose-6-phosphate isomerase;
PDBTitle: crystal structure of substrate-bound glucose-6-phosphate isomerase2 from toxoplasma gondii
71d1tmoa2
not modelled 92.9 16 Fold:Formate dehydrogenase/DMSO reductase, domains 1-3
Superfamily:Formate dehydrogenase/DMSO reductase, domains 1-3
Family:Formate dehydrogenase/DMSO reductase, domains 1-3
72c1tmoA_
not modelled 91.1 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:trimethylamine n-oxide reductase;
PDBTitle: trimethylamine n-oxide reductase from shewanella massilia
73d1dmra2
not modelled 88.3 18 Fold:Formate dehydrogenase/DMSO reductase, domains 1-3
Superfamily:Formate dehydrogenase/DMSO reductase, domains 1-3
Family:Formate dehydrogenase/DMSO reductase, domains 1-3
74d1p3da1
not modelled 88.1 20 Fold:MurCD N-terminal domain
Superfamily:MurCD N-terminal domain
Family:MurCD N-terminal domain
75c2zkqb_
not modelled 85.3 12 PDB header:ribosomal protein/rna
Chain: B: PDB Molecule:rna expansion segment es3;
PDBTitle: structure of a mammalian ribosomal 40s subunit within an2 80s complex obtained by docking homology models of the rna3 and proteins into an 8.7 a cryo-em map
76c3iz6A_
not modelled 85.1 13 PDB header:ribosome
Chain: A: PDB Molecule:40s ribosomal protein sa (s2p);
PDBTitle: localization of the small subunit ribosomal proteins into a 5.5 a2 cryo-em map of triticum aestivum translating 80s ribosome
77c1h5nC_
not modelled 85.1 19 PDB header:oxidoreductase
Chain: C: PDB Molecule:dmso reductase;
PDBTitle: dmso reductase modified by the presence of dms and air
78c2vpyE_
not modelled 84.7 13 PDB header:oxidoreductase
Chain: E: PDB Molecule:thiosulfate reductase;
PDBTitle: polysulfide reductase with bound quinone inhibitor,2 pentachlorophenol (pcp)
79d1eu1a2
not modelled 83.8 14 Fold:Formate dehydrogenase/DMSO reductase, domains 1-3
Superfamily:Formate dehydrogenase/DMSO reductase, domains 1-3
Family:Formate dehydrogenase/DMSO reductase, domains 1-3
80c2ivfA_
not modelled 82.8 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:ethylbenzene dehydrogenase alpha-subunit;
PDBTitle: ethylbenzene dehydrogenase from aromatoleum aromaticum
81d1j6ua1
not modelled 80.9 13 Fold:MurCD N-terminal domain
Superfamily:MurCD N-terminal domain
Family:MurCD N-terminal domain
82c2e7zA_
not modelled 80.5 15 PDB header:lyase
Chain: A: PDB Molecule:acetylene hydratase ahy;
PDBTitle: acetylene hydratase from pelobacter acetylenicus
83c2e4gB_
not modelled 80.2 19 PDB header:biosynthetic protein, flavoprotein
Chain: B: PDB Molecule:tryptophan halogenase;
PDBTitle: rebh with bound l-trp
84d2iv2x2
not modelled 79.9 14 Fold:Formate dehydrogenase/DMSO reductase, domains 1-3
Superfamily:Formate dehydrogenase/DMSO reductase, domains 1-3
Family:Formate dehydrogenase/DMSO reductase, domains 1-3
85c2f00A_
not modelled 79.6 18 PDB header:ligase
Chain: A: PDB Molecule:udp-n-acetylmuramate--l-alanine ligase;
PDBTitle: escherichia coli murc
86c2iv2X_
not modelled 79.3 13 PDB header:oxidoreductase
Chain: X: PDB Molecule:formate dehydrogenase h;
PDBTitle: reinterpretation of reduced form of formate dehydrogenase h2 from e. coli
87c1vlfQ_
not modelled 79.1 18 PDB header:oxidoreductase
Chain: Q: PDB Molecule:pyrogallol hydroxytransferase large subunit;
PDBTitle: crystal structure of pyrogallol-phloroglucinol2 transhydroxylase from pelobacter acidigallici complexed3 with inhibitor 1,2,4,5-tetrahydroxy-benzene
88c2xznB_
not modelled 77.3 7 PDB header:ribosome
Chain: B: PDB Molecule:rps0e;
PDBTitle: crystal structure of the eukaryotic 40s ribosomal2 subunit in complex with initiation factor 1. this file3 contains the 40s subunit and initiation factor for4 molecule 2
89c1v0jB_
not modelled 74.8 9 PDB header:isomerase
Chain: B: PDB Molecule:udp-galactopyranose mutase;
PDBTitle: udp-galactopyranose mutase from mycobacterium tuberculosis
90c3fpjA_
not modelled 74.8 11 PDB header:biosynthetic protein, transferase
Chain: A: PDB Molecule:putative uncharacterized protein;
PDBTitle: crystal structure of e81q mutant of mtnas in complex with s-2 adenosylmethionine
91d1vlfm2
not modelled 74.6 17 Fold:Formate dehydrogenase/DMSO reductase, domains 1-3
Superfamily:Formate dehydrogenase/DMSO reductase, domains 1-3
Family:Formate dehydrogenase/DMSO reductase, domains 1-3
92d2dw4a2
not modelled 74.5 25 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD-linked reductases, N-terminal domain
93c2bi8A_
not modelled 74.4 26 PDB header:isomerase
Chain: A: PDB Molecule:udp-galactopyranose mutase;
PDBTitle: udp-galactopyranose mutase from klebsiella pneumoniae with2 reduced fad
94c2ardA_
not modelled 72.6 16 PDB header:biosynthetic protein
Chain: A: PDB Molecule:tryptophan halogenase prna;
PDBTitle: the structure of tryptophan 7-halogenase (prna) suggests a mechanism2 for regioselective chlorination
95c2jb1B_
not modelled 72.2 22 PDB header:oxidoreductase
Chain: B: PDB Molecule:l-amino acid oxidase;
PDBTitle: the l-amino acid oxidase from rhodococcus opacus in complex2 with l-alanine
96d1pkla3
not modelled 71.7 16 Fold:Pyruvate kinase C-terminal domain-like
Superfamily:PK C-terminal domain-like
Family:Pyruvate kinase, C-terminal domain
97c1sezA_
not modelled 71.6 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:protoporphyrinogen oxidase, mitochondrial;
PDBTitle: crystal structure of protoporphyrinogen ix oxidase
98c2pyxA_
not modelled 71.5 16 PDB header:biosynthetic protein
Chain: A: PDB Molecule:tryptophan halogenase;
PDBTitle: crystal structure of tryptophan halogenase (yp_750003.1) from2 shewanella frigidimarina ncimb 400 at 1.50 a resolution
99c2e1mA_
not modelled 71.3 26 PDB header:oxidoreductase
Chain: A: PDB Molecule:l-glutamate oxidase;
PDBTitle: crystal structure of l-glutamate oxidase from streptomyces sp. x-119-6
100d1e0ta3
not modelled 70.9 19 Fold:Pyruvate kinase C-terminal domain-like
Superfamily:PK C-terminal domain-like
Family:Pyruvate kinase, C-terminal domain
101c3bchA_
not modelled 70.1 11 PDB header:cell adhesion, ribosomal protein
Chain: A: PDB Molecule:40s ribosomal protein sa;
PDBTitle: crystal structure of the human laminin receptor precursor
102c1eu1A_
not modelled 70.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:dimethyl sulfoxide reductase;
PDBTitle: the crystal structure of rhodobacter sphaeroides dimethylsulfoxide2 reductase reveals two distinct molybdenum coordination environments.
103d2jfga1
not modelled 68.5 17 Fold:MurCD N-terminal domain
Superfamily:MurCD N-terminal domain
Family:MurCD N-terminal domain
104c2v1dA_
not modelled 67.6 17 PDB header:oxidoreductase/repressor
Chain: A: PDB Molecule:lysine-specific histone demethylase 1;
PDBTitle: structural basis of lsd1-corest selectivity in histone h32 recognition
105c2xagA_
not modelled 67.5 17 PDB header:transcription
Chain: A: PDB Molecule:lysine-specific histone demethylase 1;
PDBTitle: crystal structure of lsd1-corest in complex with para-bromo-2 (-)-trans-2-phenylcyclopropyl-1-amine
106d1reoa1
not modelled 67.2 36 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD-linked reductases, N-terminal domain
107c2weuD_
not modelled 66.5 15 PDB header:antifungal protein
Chain: D: PDB Molecule:tryptophan 5-halogenase;
PDBTitle: crystal structure of tryptophan 5-halogenase (pyrh) complex2 with substrate tryptophan
108c2hkoA_
not modelled 66.5 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:lysine-specific histone demethylase 1;
PDBTitle: crystal structure of lsd1
109c3jwpA_
not modelled 66.1 7 PDB header:transcription
Chain: A: PDB Molecule:transcriptional regulatory protein sir2 homologue;
PDBTitle: crystal structure of plasmodium falciparum sir2a (pf13_0152) in2 complex with amp
110c2fymA_
not modelled 64.8 20 PDB header:lyase
Chain: A: PDB Molecule:enolase;
PDBTitle: crystal structure of e. coli enolase complexed with the2 minimal binding segment of rnase e.
111c3k35D_
not modelled 64.3 25 PDB header:hydrolase
Chain: D: PDB Molecule:nad-dependent deacetylase sirtuin-6;
PDBTitle: crystal structure of human sirt6
112c1f8sA_
not modelled 63.8 31 PDB header:oxidoreductase
Chain: A: PDB Molecule:l-amino acid oxidase;
PDBTitle: crystal structure of l-amino acid oxidase from calloselasma2 rhodostoma, complexed with three molecules of o-aminobenzoate.
113d1w6ta1
not modelled 63.5 20 Fold:TIM beta/alpha-barrel
Superfamily:Enolase C-terminal domain-like
Family:Enolase
114c3pkiF_
not modelled 63.2 25 PDB header:hydrolase
Chain: F: PDB Molecule:nad-dependent deacetylase sirtuin-6;
PDBTitle: human sirt6 crystal structure in complex with adp ribose
115d1pdza1
not modelled 62.1 16 Fold:TIM beta/alpha-barrel
Superfamily:Enolase C-terminal domain-like
Family:Enolase
116d2iida1
not modelled 61.9 33 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD-linked reductases, N-terminal domain
117d1yc5a1
not modelled 61.3 21 Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Sir2 family of transcriptional regulators
118c1y5iA_
not modelled 61.3 6 PDB header:oxidoreductase
Chain: A: PDB Molecule:respiratory nitrate reductase 1 alpha chain;
PDBTitle: the crystal structure of the narghi mutant nari-k86a
119c3allA_
not modelled 60.2 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase;
PDBTitle: crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid2 oxygenase, mutant y270a
120d1liua3
not modelled 59.9 19 Fold:Pyruvate kinase C-terminal domain-like
Superfamily:PK C-terminal domain-like
Family:Pyruvate kinase, C-terminal domain

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0