Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	P	F	L	R	W	C	F	V	A	T	A	L	T	L	A	G	C	S	N	T	S	W	R	K	S	E	V	L	A	V	P	L	Q	P	T	L	Q	Q	E	V	I	L	A	R	M	E	Q	I	L	A	S	R	A	L	T	D	D	E
Secondary structure
SS confidence
Disorder		?	?	?													?			?		?	?	?	?		?										?	?	?	?																	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	A	Q	L	L	Y	E	R	G	V	L	Y	D	S	L	G	L	R	A	L	A	R	N	D	F	S	Q	A	L	A	I	R	P	D	M	P	E	V	F	N	Y	L	G	I	Y	L	T	Q	A	G	N	F	D	A	A	Y	E	A	F	D
Secondary structure
SS confidence
Disorder																?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		S	V	L	E	L	D	P	T	Y	N	Y	A	H	L	N	R	G	I	A	L	Y	Y	G	G	R	D	K	L	A	Q	D	D	L	L	A	F	Y	Q	D	D	P	N	D	P	F	R	S	L	W	L	Y	L	A	E	Q	K	L	D	E	K
Secondary structure
SS confidence
Disorder																																																									?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Q	A	K	E	V	L	K	Q	H	F	E	K	S	D	K	E	Q	W	G	W	N	I	V	E	F	Y	L	G	N	I	S	E	Q	T	L	M	E	R	L	K	A	D	A	T	D	N	T	S	L	A	E	H	L	S	E	T	N	F	Y	L
Secondary structure
SS confidence
Disorder																																	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.
Sequence		G	K	Y	Y	L	S	L	G	D	L	D	S	A	T	A	L	F	K	L	A	V	A	N	N	V	H	N	F	V	E	H	R	Y	A	L	L	E	L	S	L	L	G	Q	D	Q	D	D	L	A	E	S	D	Q	Q
Secondary structure
SS confidence
Disorder																																																				?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1xnf chain A Region: 26 - 284 Aligned: 259 Modelled: 259 Confidence: 100.0% Identity: 99% Fold: alpha-alpha superhelix Superfamily: TPR-like Family: Tetratricopeptide repeat (TPR) Phyre2 PDB 1w3b chain A Region: 29 - 287 Aligned: 251 Modelled: 259 Confidence: 100.0% Identity: 19% Fold: alpha-alpha superhelix Superfamily: TPR-like Family: Tetratricopeptide repeat (TPR) Phyre2 PDB 1fch chain B Region: 54 - 292 Aligned: 236 Modelled: 236 Confidence: 99.9% Identity: 18% PDB header:signaling protein Chain: B: PDB Molecule:peroxisomal targeting signal 1 receptor; PDBTitle: crystal structure of the pts1 complexed to the tpr region2 of human pex5 Phyre2 PDB 2y4t chain A Region: 60 - 292 Aligned: 229 Modelled: 233 Confidence: 99.9% Identity: 17% PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily c member 3; PDBTitle: crystal structure of the human co-chaperone p58(ipk) Phyre2 PDB 1fch chain A Region: 45 - 292 Aligned: 245 Modelled: 245 Confidence: 99.9% Identity: 17% Fold: alpha-alpha superhelix Superfamily: TPR-like Family: Tetratricopeptide repeat (TPR) Phyre2 PDB 1dce chain A domain 1 Region: 37 - 292 Aligned: 245 Modelled: 256 Confidence: 99.9% Identity: 13% Fold: alpha-alpha superhelix Superfamily: Protein prenylyltransferase Family: Protein prenylyltransferase Phyre2 PDB 3ieg chain B Region: 62 - 290 Aligned: 225 Modelled: 229 Confidence: 99.9% Identity: 16% PDB header:chaperone Chain: B: PDB Molecule:dnaj homolog subfamily c member 3; PDBTitle: crystal structure of p58(ipk) tpr domain at 2.5 a Phyre2 PDB 2xpi chain A Region: 9 - 280 Aligned: 264 Modelled: 272 Confidence: 99.9% Identity: 16% PDB header:cell cycle Chain: A: PDB Molecule:anaphase-promoting complex subunit cut9; PDBTitle: crystal structure of apc/c hetero-tetramer cut9-hcn1 Phyre2 PDB 3cvp chain A Region: 55 - 293 Aligned: 231 Modelled: 236 Confidence: 99.9% Identity: 16% PDB header:transport protein Chain: A: PDB Molecule:peroxisome targeting signal 1 receptor pex5; PDBTitle: structure of peroxisomal targeting signal 1 (pts1) binding2 domain of trypanosoma brucei peroxin 5 (tbpex5)complexed3 to pts1 peptide (10-skl) Phyre2 PDB 3fp4 chain A Region: 47 - 286 Aligned: 240 Modelled: 240 Confidence: 99.9% Identity: 21% PDB header:transport protein Chain: A: PDB Molecule:tpr repeat-containing protein yhr117w; PDBTitle: crystal structure of tom71 complexed with ssa1 c-terminal2 fragment Phyre2 PDB 3pe3 chain D Region: 57 - 268 Aligned: 176 Modelled: 176 Confidence: 99.9% Identity: 16% PDB header:transferase Chain: D: PDB Molecule:udp-n-acetylglucosamine--peptide n- PDBTitle: structure of human o-glcnac transferase and its complex with a peptide2 substrate Phyre2 PDB 2gw1 chain A Region: 57 - 291 Aligned: 234 Modelled: 235 Confidence: 99.9% Identity: 25% PDB header:protein transport Chain: A: PDB Molecule:mitochondrial precursor proteins import receptor; PDBTitle: crystal structure of the yeast tom70 Phyre2 PDB 3q75 chain A Region: 30 - 279 Aligned: 246 Modelled: 250 Confidence: 99.9% Identity: 11% PDB header:transferase Chain: A: PDB Molecule:farnesyltransferase alpha subunit; PDBTitle: cryptococcus neoformans protein farnesyltransferase in complex with2 fpt-ii and tkcvvm peptide Phyre2 PDB 1d8d chain A Region: 29 - 288 Aligned: 254 Modelled: 260 Confidence: 99.9% Identity: 13% Fold: alpha-alpha superhelix Superfamily: Protein prenylyltransferase Family: Protein prenylyltransferase Phyre2 PDB 2h6f chain A domain 1 Region: 37 - 278 Aligned: 236 Modelled: 242 Confidence: 99.9% Identity: 13% Fold: alpha-alpha superhelix Superfamily: Protein prenylyltransferase Family: Protein prenylyltransferase Phyre2 PDB 3dra chain A Region: 29 - 275 Aligned: 243 Modelled: 247 Confidence: 99.9% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:protein PDBTitle: candida albicans protein geranylgeranyltransferase-i2 complexed with ggpp Phyre2 PDB 1tno chain I Region: 30 - 278 Aligned: 243 Modelled: 249 Confidence: 99.9% Identity: 13% PDB header:transferase Chain: I: PDB Molecule:geranylgeranyltransferase type i alpha subunit; PDBTitle: rat protein geranylgeranyltransferase type-i complexed with2 a ggpp analog and a kkksktkcvim peptide derived from k-3 ras4b Phyre2 PDB 3urz chain B Region: 62 - 288 Aligned: 202 Modelled: 209 Confidence: 99.9% Identity: 11% PDB header:protein binding Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a hypothetical protein (bacova_03105) from2 bacteroides ovatus atcc 8483 at 2.19 a resolution Phyre2 PDB 3hym chain B Region: 63 - 283 Aligned: 217 Modelled: 221 Confidence: 99.9% Identity: 11% PDB header:cell cycle, ligase Chain: B: PDB Molecule:cell division cycle protein 16 homolog; PDBTitle: insights into anaphase promoting complex tpr subdomain2 assembly from a cdc26-apc6 structure Phyre2 PDB 2ho1 chain B Region: 57 - 273 Aligned: 214 Modelled: 217 Confidence: 99.9% Identity: 16% PDB header:protein binding Chain: B: PDB Molecule:type 4 fimbrial biogenesis protein pilf; PDBTitle: functional characterization of pseudomonas aeruginosa pilf Phyre2 1 d1xnfa_ 2 d1w3ba_ 3 c1fchB_ 4 c2y4tA_ 5 d1fcha_ 6 d1dcea1 7 c3iegB_ 8 c2xpiA_ 9 c3cvpA_ 10 c3fp4A_ 11 c3pe3D_ 12 c2gw1A_ 13 c3q75A_ 14 d1d8da_ 15 d2h6fa1 16 c3draA_ 17 c1tnoI_ 18 c3urzB_ 19 c3hymB_ 20 c2ho1B_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1xnfa_ 100.0 99 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 2 d1w3ba_ 100.0 19 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 3 c1fchB_ 99.9 18 PDB header:signaling protein Chain: B: PDB Molecule:peroxisomal targeting signal 1 receptor; PDBTitle: crystal structure of the pts1 complexed to the tpr region2 of human pex5 4 c2y4tA_ 99.9 17 PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily c member 3; PDBTitle: crystal structure of the human co-chaperone p58(ipk) 5 d1fcha_ 99.9 17 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 6 d1dcea1 99.9 13 Fold:alpha-alpha superhelix Superfamily:Protein prenylyltransferase Family:Protein prenylyltransferase 7 c3iegB_ 99.9 16 PDB header:chaperone Chain: B: PDB Molecule:dnaj homolog subfamily c member 3; PDBTitle: crystal structure of p58(ipk) tpr domain at 2.5 a 8 c2xpiA_ 99.9 16 PDB header:cell cycle Chain: A: PDB Molecule:anaphase-promoting complex subunit cut9; PDBTitle: crystal structure of apc/c hetero-tetramer cut9-hcn1 9 c3cvpA_ 99.9 16 PDB header:transport protein Chain: A: PDB Molecule:peroxisome targeting signal 1 receptor pex5; PDBTitle: structure of peroxisomal targeting signal 1 (pts1) binding2 domain of trypanosoma brucei peroxin 5 (tbpex5)complexed3 to pts1 peptide (10-skl) 10 c3fp4A_ 99.9 21 PDB header:transport protein Chain: A: PDB Molecule:tpr repeat-containing protein yhr117w; PDBTitle: crystal structure of tom71 complexed with ssa1 c-terminal2 fragment 11 c3pe3D_ 99.9 16 PDB header:transferase Chain: D: PDB Molecule:udp-n-acetylglucosamine--peptide n- PDBTitle: structure of human o-glcnac transferase and its complex with a peptide2 substrate 12 c2gw1A_ 99.9 25 PDB header:protein transport Chain: A: PDB Molecule:mitochondrial precursor proteins import receptor; PDBTitle: crystal structure of the yeast tom70 13 c3q75A_ 99.9 11 PDB header:transferase Chain: A: PDB Molecule:farnesyltransferase alpha subunit; PDBTitle: cryptococcus neoformans protein farnesyltransferase in complex with2 fpt-ii and tkcvvm peptide 14 d1d8da_ 99.9 13 Fold:alpha-alpha superhelix Superfamily:Protein prenylyltransferase Family:Protein prenylyltransferase 15 d2h6fa1 99.9 13 Fold:alpha-alpha superhelix Superfamily:Protein prenylyltransferase Family:Protein prenylyltransferase 16 c3draA_ 99.9 14 PDB header:transferase Chain: A: PDB Molecule:protein PDBTitle: candida albicans protein geranylgeranyltransferase-i2 complexed with ggpp 17 c1tnoI_ 99.9 13 PDB header:transferase Chain: I: PDB Molecule:geranylgeranyltransferase type i alpha subunit; PDBTitle: rat protein geranylgeranyltransferase type-i complexed with2 a ggpp analog and a kkksktkcvim peptide derived from k-3 ras4b 18 c3urzB_ 99.9 11 PDB header:protein binding Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a hypothetical protein (bacova_03105) from2 bacteroides ovatus atcc 8483 at 2.19 a resolution 19 c3hymB_ 99.9 11 PDB header:cell cycle, ligase Chain: B: PDB Molecule:cell division cycle protein 16 homolog; PDBTitle: insights into anaphase promoting complex tpr subdomain2 assembly from a cdc26-apc6 structure 20 c2ho1B_ 99.9 16 PDB header:protein binding Chain: B: PDB Molecule:type 4 fimbrial biogenesis protein pilf; PDBTitle: functional characterization of pseudomonas aeruginosa pilf 21 c3as5A_ not modelled 99.9 19 PDB header:protein binding Chain: A: PDB Molecule:mama; PDBTitle: mama amb-1 p212121 22 c2q7fA_ not modelled 99.9 14 PDB header:protein binding Chain: A: PDB Molecule:yrrb protein; PDBTitle: crystal structure of yrrb: a tpr protein with an unusual peptide-2 binding site 23 c2vq2A_ not modelled 99.9 14 PDB header:structural protein Chain: A: PDB Molecule:putative fimbrial biogenesis and twitching PDBTitle: crystal structure of pilw, widely conserved type iv pilus2 biogenesis factor 24 c2pl2A_ not modelled 99.9 20 PDB header:protein binding Chain: A: PDB Molecule:hypothetical conserved protein ttc0263; PDBTitle: crystal structure of ttc0263: a thermophilic tpr protein in thermus2 thermophilus hb27 25 c3sf4B_ not modelled 99.8 11 PDB header:signaling protein/protein binding Chain: B: PDB Molecule:g-protein-signaling modulator 2; PDBTitle: crystal structure of the complex between the conserved cell polarity2 proteins inscuteable and lgn 26 c3mkrA_ not modelled 99.8 11 PDB header:transport protein Chain: A: PDB Molecule:coatomer subunit epsilon; PDBTitle: crystal structure of yeast alpha/epsilon-cop subcomplex of the copi2 vesicular coat 27 d1hz4a_ not modelled 99.8 12 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Transcription factor MalT domain III 28 d2c2la1 not modelled 99.8 13 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 29 c2hyzA_ not modelled 99.8 32 PDB header:de novo protein Chain: A: PDB Molecule:synthetic consensus tpr protein; PDBTitle: crystal structure of an 8 repeat consensus tpr superhelix2 (orthorombic crystal form) 30 d1hh8a_ not modelled 99.8 20 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 31 c3mv3B_ not modelled 99.8 13 PDB header:protein transport Chain: B: PDB Molecule:coatomer subunit epsilon; PDBTitle: crystal structure of a-cop in complex with e-cop 32 c3q15A_ not modelled 99.8 11 PDB header:hydrolase/kinase Chain: A: PDB Molecule:response regulator aspartate phosphatase h; PDBTitle: crystal structure of raph complexed with spo0f 33 c2r5sB_ not modelled 99.8 16 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein vp0806; PDBTitle: the crystal structure of a domain of protein vp0806 (unknown function)2 from vibrio parahaemolyticus rimd 2210633 34 c2ifuA_ not modelled 99.8 11 PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:gamma-snap; PDBTitle: crystal structure of a gamma-snap from danio rerio 35 d2ooea1 not modelled 99.7 9 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:HAT/Suf repeat 36 c1wao4_ not modelled 99.7 17 PDB header:hydrolase Chain: 4: PDB Molecule:serine/threonine protein phosphatase 5; PDBTitle: pp5 structure 37 c2uy1A_ not modelled 99.7 11 PDB header:rna-binding protein Chain: A: PDB Molecule:cleavage stimulation factor 77; PDBTitle: crystal structure of cstf-77 38 c2c2lD_ not modelled 99.7 13 PDB header:chaperone Chain: D: PDB Molecule:carboxy terminus of hsp70-interacting protein; PDBTitle: crystal structure of the chip u-box e3 ubiquitin ligase 39 c3nf1A_ not modelled 99.7 16 PDB header:motor protein, transport protein Chain: A: PDB Molecule:kinesin light chain 1; PDBTitle: crystal structure of the tpr domain of kinesin light chain 1 40 c2vyiA_ not modelled 99.7 22 PDB header:chaperone Chain: A: PDB Molecule:sgta protein; PDBTitle: crystal structure of the tpr domain of human sgt 41 d1qsaa1 not modelled 99.7 10 Fold:alpha-alpha superhelix Superfamily:Bacterial muramidases Family:Bacterial muramidases 42 c2e2eA_ not modelled 99.7 12 PDB header:lyase Chain: A: PDB Molecule:formate-dependent nitrite reductase complex nrfg subunit; PDBTitle: tpr domain of nrfg mediates the complex formation between heme lyase2 and formate-dependent nitrite reductase in escherichia coli o157:h7 43 c3gw4B_ not modelled 99.7 15 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of uncharacterized protein from deinococcus2 radiodurans. northeast structural genomics consortium target drr162b. 44 d1elwa_ not modelled 99.7 21 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 45 c2yhcA_ not modelled 99.7 13 PDB header:membrane protein Chain: A: PDB Molecule:upf0169 lipoprotein yfio; PDBTitle: structure of bamd from e. coli 46 c2xcbA_ not modelled 99.7 14 PDB header:protein binding Chain: A: PDB Molecule:regulatory protein pcrh; PDBTitle: crystal structure of pcrh in complex with the chaperone2 binding region of popd 47 c3ceqB_ not modelled 99.6 18 PDB header:motor protein, transport protein Chain: B: PDB Molecule:kinesin light chain 2; PDBTitle: the tpr domain of human kinesin light chain 2 (hklc2) 48 c3qkyA_ not modelled 99.6 10 PDB header:membrane protein Chain: A: PDB Molecule:outer membrane assembly lipoprotein yfio; PDBTitle: crystal structure of rhodothermus marinus bamd 49 c3gyzB_ not modelled 99.6 11 PDB header:chaperone Chain: B: PDB Molecule:chaperone protein ipgc; PDBTitle: crystal structure of ipgc from shigella flexneri 50 d1a17a_ not modelled 99.6 17 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 51 c3sz7A_ not modelled 99.6 19 PDB header:chaperone regulator Chain: A: PDB Molecule:hsc70 cochaperone (sgt); PDBTitle: crystal structure of the sgt2 tpr domain from aspergillus fumigatus 52 c3rkvA_ not modelled 99.6 21 PDB header:isomerase Chain: A: PDB Molecule:putative peptidylprolyl isomerase; PDBTitle: c-terminal domain of protein c56c10.10, a putative peptidylprolyl2 isomerase, from caenorhabditis elegans 53 c2kckA_ not modelled 99.6 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:tpr repeat; PDBTitle: nmr solution structure of the northeast structural genomics2 consortium (nesg) target mrr121a 54 d2buga1 not modelled 99.6 17 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 55 c3q49B_ not modelled 99.6 16 PDB header:ligase/chaperone Chain: B: PDB Molecule:stip1 homology and u box-containing protein 1; PDBTitle: crystal structure of the tpr domain of chip complexed with hsp70-c2 peptide 56 c2dbaA_ not modelled 99.5 20 PDB header:structural protein Chain: A: PDB Molecule:smooth muscle cell associated protein-1, isoform PDBTitle: the solution structure of the tetratrico peptide repeat of2 human smooth muscle cell associated protein-1, isoform 2 57 d1hxia_ not modelled 99.5 20 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 58 d1zu2a1 not modelled 99.5 19 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 59 c3ly8A_ not modelled 99.5 6 PDB header:signaling protein Chain: A: PDB Molecule:transcriptional activator cadc; PDBTitle: crystal structure of mutant d471e of the periplasmic domain of cadc 60 d2hr2a1 not modelled 99.5 14 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:CT2138-like 61 d1kt1a1 not modelled 99.5 22 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 62 c2vsnB_ not modelled 99.5 16 PDB header:transferase Chain: B: PDB Molecule:xcogt; PDBTitle: structure and topological arrangement of an o-glcnac2 transferase homolog: insight into molecular control of3 intracellular glycosylation 63 c1ihgA_ not modelled 99.5 22 PDB header:isomerase Chain: A: PDB Molecule:cyclophilin 40; PDBTitle: bovine cyclophilin 40, monoclinic form 64 c3qdnA_ not modelled 99.5 17 PDB header:oxidoreductase Chain: A: PDB Molecule:putative thioredoxin protein; PDBTitle: putative thioredoxin protein from salmonella typhimurium 65 d1p5qa1 not modelled 99.5 23 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 66 d1qqea_ not modelled 99.5 13 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 67 d1elra_ not modelled 99.5 13 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 68 d2fbna1 not modelled 99.4 21 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 69 c2fbnA_ not modelled 99.4 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:70 kda peptidylprolyl isomerase, putative; PDBTitle: plasmodium falciparum putative fk506-binding protein2 pfl2275c, c-terminal tpr-containing domain 70 c3k9iA_ not modelled 99.4 13 PDB header:protein binding Chain: A: PDB Molecule:bh0479 protein; PDBTitle: crystal structure of putative protein binding protein (np_241345.1)2 from bacillus halodurans at 2.71 a resolution 71 c1xi4D_ not modelled 99.4 12 PDB header:endocytosis/exocytosis Chain: D: PDB Molecule:clathrin heavy chain; PDBTitle: clathrin d6 coat 72 c1kt0A_ not modelled 99.4 18 PDB header:isomerase Chain: A: PDB Molecule:51 kda fk506-binding protein; PDBTitle: structure of the large fkbp-like protein, fkbp51, involved in steroid2 receptor complexes 73 d1ihga1 not modelled 99.4 18 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 74 c1na3A_ not modelled 99.4 31 PDB header:de novo protein Chain: A: PDB Molecule:designed protein ctpr2; PDBTitle: design of stable alpha-helical arrays from an idealized tpr2 motif 75 c1ltxA_ not modelled 99.4 11 PDB header:transferase/protein binding Chain: A: PDB Molecule:rab geranylgeranyltransferase alpha subunit; PDBTitle: structure of rab escort protein-1 in complex with rab2 geranylgeranyl transferase and isoprenoid 76 c1qz2B_ not modelled 99.4 23 PDB header:isomerase/chaperone Chain: B: PDB Molecule:fk506-binding protein 4; PDBTitle: crystal structure of fkbp52 c-terminal domain complex with2 the c-terminal peptide meevd of hsp90 77 c2xevB_ not modelled 99.4 23 PDB header:metal binding Chain: B: PDB Molecule:ybgf; PDBTitle: crystal structure of the tpr domain of xanthomonas2 campestris ybgf 78 d2onda1 not modelled 99.3 11 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:HAT/Suf repeat 79 c2l6jA_ not modelled 99.3 17 PDB header:protein binding Chain: A: PDB Molecule:tpr repeat-containing protein associated with hsp90; PDBTitle: tah1 complexed by meevd 80 c2katA_ not modelled 99.3 20 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution structure of protein bpp2914 from bordetella2 parapertussis. northeast structural genomics consortium3 target bpr206 81 c2if4A_ not modelled 99.3 18 PDB header:signaling protein Chain: A: PDB Molecule:atfkbp42; PDBTitle: crystal structure of a multi-domain immunophilin from2 arabidopsis thaliana 82 d1nzna_ not modelled 99.3 9 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 83 c2vgxA_ not modelled 99.3 15 PDB header:chaperone Chain: A: PDB Molecule:chaperone sycd; PDBTitle: structure of the yersinia enterocolitica type iii secretion2 translocator chaperone sycd 84 c2avpA_ not modelled 99.3 31 PDB header:de novo protein Chain: A: PDB Molecule:synthetic consensus tpr protein; PDBTitle: crystal structure of an 8 repeat consensus tpr superhelix 85 d1iyga_ not modelled 99.3 9 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 86 c2kcvA_ not modelled 99.2 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:tetratricopeptide repeat domain protein; PDBTitle: solution nmr structure of tetratricopeptide repeat domain2 protein sru_0103 from salinibacter ruber, northeast3 structural genomics consortium (nesg) target srr115c 87 d1pc2a_ not modelled 99.2 10 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 88 c3fflC_ not modelled 99.2 13 PDB header:cell cycle Chain: C: PDB Molecule:anaphase-promoting complex subunit 7; PDBTitle: crystal structure of the n-terminal domain of anaphase-2 promoting complex subunit 7 89 d1zbpa1 not modelled 99.1 10 Fold:ImpE-like Superfamily:ImpE-like Family:ImpE-like 90 d1ouva_ not modelled 99.1 15 Fold:alpha-alpha superhelix Superfamily:HCP-like Family:HCP-like 91 c3q3hA_ not modelled 99.0 11 PDB header:transferase Chain: A: PDB Molecule:hmw1c-like glycosyltransferase; PDBTitle: crystal structure of the actinobacillus pleuropneumoniae hmw1c2 glycosyltransferase in complex with udp-glc 92 c1slyA_ not modelled 99.0 8 PDB header:glycosyltransferase Chain: A: PDB Molecule:70-kda soluble lytic transglycosylase; PDBTitle: complex of the 70-kda soluble lytic transglycosylase with2 bulgecin a 93 d1tjca_ not modelled 99.0 27 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 94 c2kc7A_ not modelled 98.9 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:bfr218_protein; PDBTitle: solution nmr structure of bacteroides fragilis protein2 bf1650. northeast structural genomics consortium target3 bfr218 95 d1y8ma1 not modelled 98.8 11 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 96 c3beeB_ not modelled 98.7 11 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative yfre protein; PDBTitle: crystal structure of putative yfre protein from vibrio2 parahaemolyticus 97 c3n71A_ not modelled 98.7 11 PDB header:transcription Chain: A: PDB Molecule:histone lysine methyltransferase smyd1; PDBTitle: crystal structure of cardiac specific histone methyltransferase smyd1 98 c3e4bD_ not modelled 98.5 13 PDB header:protein binding Chain: D: PDB Molecule:algk; PDBTitle: crystal structure of algk from pseudomonas fluorescens wcs374r 99 d2pqrb1 not modelled 98.3 12 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 100 d2ff4a2 not modelled 98.2 20 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:BTAD-like 101 c3txmA_ not modelled 98.0 9 PDB header:hydrolase, protein binding Chain: A: PDB Molecule:26s proteasome regulatory complex subunit p42b; PDBTitle: crystal structure of rpn6 from drosophila melanogaster, gd(3+) complex 102 c2qfcB_ not modelled 98.0 12 PDB header:transcription regulation Chain: B: PDB Molecule:plcr protein; PDBTitle: crystal structure of bacillus thuringiensis plcr complexed with papr 103 c2xm6A_ not modelled 98.0 20 PDB header:unknown function Chain: A: PDB Molecule:protein corresponding to locus c5321 from cft073 e.coli PDBTitle: crystal structure of the protein corresponding to locus c5321 from2 cft073 e.coli strain 104 c3mekA_ not modelled 97.8 18 PDB header:transferase Chain: A: PDB Molecule:set and mynd domain-containing protein 3; PDBTitle: crystal structure of human histone-lysine n-2 methyltransferase smyd3 in complex with s-adenosyl-l-3 methionine 105 c3qwvA_ not modelled 97.8 9 PDB header:transferase Chain: A: PDB Molecule:set and mynd domain-containing protein 2; PDBTitle: crystal structure of histone lysine methyltransferase smyd2 in complex2 with the cofactor product adohcy 106 c3oxgA_ not modelled 97.6 10 PDB header:transferase Chain: A: PDB Molecule:set and mynd domain-containing protein 3; PDBTitle: human lysine methyltransferase smyd3 in complex with adohcy (form iii) 107 d1iipa1 not modelled 97.5 18 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 108 c3rjvA_ not modelled 96.9 9 PDB header:protein binding Chain: A: PDB Molecule:putative sel1 repeat protein; PDBTitle: crystal structure of a putative sel1 repeat protein (kpn_04481) from2 klebsiella pneumoniae subsp. pneumoniae at 1.65 a resolution 109 d1ya0a1 not modelled 95.5 16 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 110 c2lahA_ not modelled 95.5 13 PDB header:cell cycle, apoptosis Chain: A: PDB Molecule:mitotic checkpoint serine/threonine-protein kinase bub1; PDBTitle: solution nmr structure of mitotic checkpoint serine/threonine-protein2 kinase bub1 n-terminal domain from homo sapiens, northeast structural3 genomics consortium target hr5460a (methods development) 111 c2ff4B_ not modelled 95.4 9 PDB header:transcription Chain: B: PDB Molecule:probable regulatory protein embr; PDBTitle: mycobacterium tuberculosis embr in complex with low affinity2 phosphopeptide 112 c3lvhA_ not modelled 94.1 9 PDB header:structural protein Chain: A: PDB Molecule:clathrin heavy chain 1; PDBTitle: crystal structure of a clathrin heavy chain and clathrin light chain2 complex 113 c1b89A_ not modelled 93.3 16 PDB header:clathrin Chain: A: PDB Molecule:protein (clathrin heavy chain); PDBTitle: clathrin heavy chain proximal leg segment (bovine) 114 d1b89a_ not modelled 93.3 16 Fold:alpha-alpha superhelix Superfamily:ARM repeat Family:Clathrin heavy chain proximal leg segment 115 c2wviA_ not modelled 93.3 7 PDB header:transferase Chain: A: PDB Molecule:mitotic checkpoint serine/threonine-protein PDBTitle: crystal structure of the n-terminal domain of bubr1 116 d2crba1 not modelled 90.3 16 Fold:Spectrin repeat-like Superfamily:MIT domain-like Family:MIT domain 117 c3mkqA_ not modelled 90.3 16 PDB header:transport protein Chain: A: PDB Molecule:coatomer beta'-subunit; PDBTitle: crystal structure of yeast alpha/betaprime-cop subcomplex of the copi2 vesicular coat 118 c3eslA_ not modelled 79.2 12 PDB header:cell cycle Chain: A: PDB Molecule:checkpoint serine/threonine-protein kinase bub1; PDBTitle: crystal structure of the conserved n-terminal domain of the2 mitotic checkpoint component bub1 119 d1klxa_ not modelled 77.5 13 Fold:alpha-alpha superhelix Superfamily:HCP-like Family:HCP-like 120 c2w2uA_ not modelled 77.3 16 PDB header:hydrolase/transport Chain: A: PDB Molecule:hypothetical p60 katanin; PDBTitle: structural insight into the interaction between archaeal2 escrt-iii and aaa-atpase

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0