Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	N	T	E	L	E	Q	L	I	N	E	K	L	N	S	A	A	I	S	D	Y	A	P	N	G	L	Q	V	E	G	K	E	T	V	Q	K	I	V	T	G	V	T	A	S	Q	A	L	L	D	E	A	V	R	L	G	A	D	A	V
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		I	V	H	H	G	Y	F	W	K	G	E	S	P	V	I	R	G	M	K	R	N	R	L	K	T	L	L	A	N	D	I	N	L	Y	G	W	H	L	P	L	D	A	H	P	E	L	G	N	N	A	Q	L	A	A	L	L	G	I	T	V
Secondary structure
SS confidence
Disorder														?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		M	G	E	I	E	P	L	V	P	W	G	E	L	T	M	P	V	P	G	L	E	L	A	S	W	I	E	A	R	L	G	R	K	P	L	W	C	G	D	T	G	P	E	V	V	Q	R	V	A	W	C	T	G	G	G	Q	S	F	I	D
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		S	A	A	R	F	G	V	D	A	F	I	T	G	E	V	S	E	Q	T	I	H	S	A	R	E	Q	G	L	H	F	Y	A	A	G	H	H	A	T	E	R	G	G	I	R	A	L	S	E	W	L	N	E	N	T	D	L	D	V	T	F
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.
Sequence		I	D	I	P	N	P	A
Secondary structure
SS confidence
Disorder					?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1nmp chain A Region: 1 - 247 Aligned: 247 Modelled: 247 Confidence: 100.0% Identity: 100% Fold: NIF3 (NGG1p interacting factor 3)-like Superfamily: NIF3 (NGG1p interacting factor 3)-like Family: NIF3 (NGG1p interacting factor 3)-like Phyre2 PDB 2nyd chain B Region: 1 - 246 Aligned: 244 Modelled: 246 Confidence: 100.0% Identity: 23% PDB header:unknown function Chain: B: PDB Molecule:upf0135 protein sa1388; PDBTitle: crystal structure of staphylococcus aureus hypothetical protein sa1388 Phyre2 PDB 2gx8 chain B Region: 1 - 246 Aligned: 244 Modelled: 246 Confidence: 100.0% Identity: 25% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:nif3-related protein; PDBTitle: the crystal stucture of bacillus cereus protein related to nif3 Phyre2 PDB 2gx8 chain A domain 1 Region: 2 - 246 Aligned: 243 Modelled: 245 Confidence: 100.0% Identity: 25% Fold: NIF3 (NGG1p interacting factor 3)-like Superfamily: NIF3 (NGG1p interacting factor 3)-like Family: NIF3 (NGG1p interacting factor 3)-like Phyre2 PDB 2yyb chain A Region: 1 - 245 Aligned: 239 Modelled: 245 Confidence: 100.0% Identity: 37% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein ttha1606; PDBTitle: crystal structure of ttha1606 from thermus thermophilus hb8 Phyre2 PDB 2fyw chain A domain 1 Region: 3 - 246 Aligned: 241 Modelled: 242 Confidence: 100.0% Identity: 24% Fold: NIF3 (NGG1p interacting factor 3)-like Superfamily: NIF3 (NGG1p interacting factor 3)-like Family: NIF3 (NGG1p interacting factor 3)-like Phyre2 PDB 3rxy chain A Region: 1 - 239 Aligned: 220 Modelled: 216 Confidence: 99.9% Identity: 20% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:nif3 protein; PDBTitle: crystal structure of nif3 superfamily protein from sphaerobacter2 thermophilus Phyre2 PDB 2yx6 chain C Region: 152 - 235 Aligned: 84 Modelled: 84 Confidence: 85.0% Identity: 12% PDB header:structural genomics, unknown function Chain: C: PDB Molecule:hypothetical protein ph0822; PDBTitle: crystal structure of ph0822 Phyre2 PDB 3qc3 chain B Region: 37 - 193 Aligned: 127 Modelled: 137 Confidence: 83.4% Identity: 14% PDB header:isomerase Chain: B: PDB Molecule:d-ribulose-5-phosphate-3-epimerase; PDBTitle: crystal structure of a d-ribulose-5-phosphate-3-epimerase (np_954699)2 from homo sapiens at 2.20 a resolution Phyre2 PDB 2am1 chain A Region: 1 - 66 Aligned: 66 Modelled: 66 Confidence: 79.3% Identity: 11% PDB header:ligase Chain: A: PDB Molecule:udp-n-acetylmuramoylalanine-d-glutamyl-lysine-d-alanyl-d- PDBTitle: sp protein ligand 1 Phyre2 PDB 1w0m chain A Region: 49 - 193 Aligned: 119 Modelled: 133 Confidence: 77.7% Identity: 18% Fold: TIM beta/alpha-barrel Superfamily: Triosephosphate isomerase (TIM) Family: Triosephosphate isomerase (TIM) Phyre2 PDB 1t3v chain A Region: 172 - 232 Aligned: 61 Modelled: 61 Confidence: 75.8% Identity: 13% Fold: Ribonuclease H-like motif Superfamily: Nitrogenase accessory factor-like Family: MTH1175-like Phyre2 PDB 1eo1 chain A Region: 172 - 232 Aligned: 61 Modelled: 61 Confidence: 75.4% Identity: 23% Fold: Ribonuclease H-like motif Superfamily: Nitrogenase accessory factor-like Family: MTH1175-like Phyre2 PDB 3e96 chain B Region: 45 - 193 Aligned: 120 Modelled: 136 Confidence: 70.8% Identity: 19% PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 bacillus clausii Phyre2 PDB 2wfb chain A Region: 171 - 211 Aligned: 41 Modelled: 41 Confidence: 67.3% Identity: 20% PDB header:biosynthetic protein Chain: A: PDB Molecule:putative uncharacterized protein orp; PDBTitle: high resolution structure of the apo form of the orange2 protein (orp) from desulfovibrio gigas Phyre2 PDB 3d0c chain B Region: 47 - 193 Aligned: 118 Modelled: 133 Confidence: 66.0% Identity: 22% PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 oceanobacillus iheyensis at 1.9 a resolution Phyre2 PDB 3aam chain A Region: 46 - 101 Aligned: 55 Modelled: 56 Confidence: 65.6% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:endonuclease iv; PDBTitle: crystal structure of endonuclease iv from thermus thermophilus hb8 Phyre2 PDB 3c6k chain C Region: 166 - 246 Aligned: 78 Modelled: 81 Confidence: 64.4% Identity: 14% PDB header:transferase Chain: C: PDB Molecule:spermine synthase; PDBTitle: crystal structure of human spermine synthase in complex2 with spermidine and 5-methylthioadenosine Phyre2 PDB 3ct7 chain E Region: 49 - 193 Aligned: 120 Modelled: 145 Confidence: 64.1% Identity: 17% PDB header:isomerase Chain: E: PDB Molecule:d-allulose-6-phosphate 3-epimerase; PDBTitle: crystal structure of d-allulose 6-phosphate 3-epimerase2 from escherichia coli k-12 Phyre2 PDB 1p3d chain A domain 1 Region: 160 - 218 Aligned: 58 Modelled: 59 Confidence: 63.9% Identity: 17% Fold: MurCD N-terminal domain Superfamily: MurCD N-terminal domain Family: MurCD N-terminal domain Phyre2 1 d1nmpa_ 2 c2nydB_ 3 c2gx8B_ 4 d2gx8a1 5 c2yybA_ 6 d2fywa1 7 c3rxyA_ 8 c2yx6C_ 9 c3qc3B_ 10 c2am1A_ 11 d1w0ma_ 12 d1t3va_ 13 d1eo1a_ 14 c3e96B_ 15 c2wfbA_ 16 c3d0cB_ 17 c3aamA_ 18 c3c6kC_ 19 c3ct7E_ 20 d1p3da1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1nmpa_ 100.0 100 Fold:NIF3 (NGG1p interacting factor 3)-like Superfamily:NIF3 (NGG1p interacting factor 3)-like Family:NIF3 (NGG1p interacting factor 3)-like 2 c2nydB_ 100.0 23 PDB header:unknown function Chain: B: PDB Molecule:upf0135 protein sa1388; PDBTitle: crystal structure of staphylococcus aureus hypothetical protein sa1388 3 c2gx8B_ 100.0 25 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:nif3-related protein; PDBTitle: the crystal stucture of bacillus cereus protein related to nif3 4 d2gx8a1 100.0 25 Fold:NIF3 (NGG1p interacting factor 3)-like Superfamily:NIF3 (NGG1p interacting factor 3)-like Family:NIF3 (NGG1p interacting factor 3)-like 5 c2yybA_ 100.0 37 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein ttha1606; PDBTitle: crystal structure of ttha1606 from thermus thermophilus hb8 6 d2fywa1 100.0 24 Fold:NIF3 (NGG1p interacting factor 3)-like Superfamily:NIF3 (NGG1p interacting factor 3)-like Family:NIF3 (NGG1p interacting factor 3)-like 7 c3rxyA_ 99.9 20 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:nif3 protein; PDBTitle: crystal structure of nif3 superfamily protein from sphaerobacter2 thermophilus 8 c2yx6C_ 85.0 12 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:hypothetical protein ph0822; PDBTitle: crystal structure of ph0822 9 c3qc3B_ 83.4 14 PDB header:isomerase Chain: B: PDB Molecule:d-ribulose-5-phosphate-3-epimerase; PDBTitle: crystal structure of a d-ribulose-5-phosphate-3-epimerase (np_954699)2 from homo sapiens at 2.20 a resolution 10 c2am1A_ 79.3 11 PDB header:ligase Chain: A: PDB Molecule:udp-n-acetylmuramoylalanine-d-glutamyl-lysine-d-alanyl-d- PDBTitle: sp protein ligand 1 11 d1w0ma_ 77.7 18 Fold:TIM beta/alpha-barrel Superfamily:Triosephosphate isomerase (TIM) Family:Triosephosphate isomerase (TIM) 12 d1t3va_ 75.8 13 Fold:Ribonuclease H-like motif Superfamily:Nitrogenase accessory factor-like Family:MTH1175-like 13 d1eo1a_ 75.4 23 Fold:Ribonuclease H-like motif Superfamily:Nitrogenase accessory factor-like Family:MTH1175-like 14 c3e96B_ 70.8 19 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 bacillus clausii 15 c2wfbA_ 67.3 20 PDB header:biosynthetic protein Chain: A: PDB Molecule:putative uncharacterized protein orp; PDBTitle: high resolution structure of the apo form of the orange2 protein (orp) from desulfovibrio gigas 16 c3d0cB_ 66.0 22 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 oceanobacillus iheyensis at 1.9 a resolution 17 c3aamA_ 65.6 15 PDB header:hydrolase Chain: A: PDB Molecule:endonuclease iv; PDBTitle: crystal structure of endonuclease iv from thermus thermophilus hb8 18 c3c6kC_ 64.4 14 PDB header:transferase Chain: C: PDB Molecule:spermine synthase; PDBTitle: crystal structure of human spermine synthase in complex2 with spermidine and 5-methylthioadenosine 19 c3ct7E_ 64.1 17 PDB header:isomerase Chain: E: PDB Molecule:d-allulose-6-phosphate 3-epimerase; PDBTitle: crystal structure of d-allulose 6-phosphate 3-epimerase2 from escherichia coli k-12 20 d1p3da1 63.9 17 Fold:MurCD N-terminal domain Superfamily:MurCD N-terminal domain Family:MurCD N-terminal domain 21 c3jr2D_ not modelled 61.3 14 PDB header:biosynthetic protein Chain: D: PDB Molecule:hexulose-6-phosphate synthase sgbh; PDBTitle: x-ray crystal structure of the mg-bound 3-keto-l-gulonate-6-phosphate2 decarboxylase from vibrio cholerae o1 biovar el tor str. n16961 22 d1afsa_ not modelled 59.8 9 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 23 c2yw3E_ not modelled 59.3 16 PDB header:lyase Chain: E: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase/2-deydro-3- PDBTitle: crystal structure analysis of the 4-hydroxy-2-oxoglutarate aldolase/2-2 deydro-3-deoxyphosphogluconate aldolase from tthb1 24 d1u83a_ not modelled 58.1 16 Fold:TIM beta/alpha-barrel Superfamily:(2r)-phospho-3-sulfolactate synthase ComA Family:(2r)-phospho-3-sulfolactate synthase ComA 25 c1u83A_ not modelled 58.1 16 PDB header:lyase Chain: A: PDB Molecule:phosphosulfolactate synthase; PDBTitle: psl synthase from bacillus subtilis 26 d1us0a_ not modelled 57.6 13 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 27 d1xp3a1 not modelled 55.8 22 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Endonuclease IV 28 d1e7wa_ not modelled 55.5 24 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 29 d1rdua_ not modelled 52.5 18 Fold:Ribonuclease H-like motif Superfamily:Nitrogenase accessory factor-like Family:MTH1175-like 30 d2flia1 not modelled 52.1 16 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 31 c3o26A_ not modelled 51.5 32 PDB header:oxidoreductase Chain: A: PDB Molecule:salutaridine reductase; PDBTitle: the structure of salutaridine reductase from papaver somniferum. 32 c3p19A_ not modelled 51.0 18 PDB header:oxidoreductase Chain: A: PDB Molecule:putative blue fluorescent protein; PDBTitle: improved nadph-dependent blue fluorescent protein 33 d1p90a_ not modelled 50.5 6 Fold:Ribonuclease H-like motif Superfamily:Nitrogenase accessory factor-like Family:Nitrogenase accessory factor 34 d3clsc1 not modelled 47.9 16 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ETFP subunits 35 c2re2A_ not modelled 47.9 12 PDB header:oxidoreductase Chain: A: PDB Molecule:uncharacterized protein ta1041; PDBTitle: crystal structure of a putative iron-molybdenum cofactor (femo-co)2 dinitrogenase (ta1041m) from thermoplasma acidophilum dsm 1728 at3 1.30 a resolution 36 d1p33a_ not modelled 47.1 20 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 37 d1h1ya_ not modelled 46.6 16 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 38 c3pdiB_ not modelled 46.2 17 PDB header:protein binding Chain: B: PDB Molecule:nitrogenase mofe cofactor biosynthesis protein nifn; PDBTitle: precursor bound nifen 39 d1j6ua1 not modelled 46.1 14 Fold:MurCD N-terminal domain Superfamily:MurCD N-terminal domain Family:MurCD N-terminal domain 40 c2foiB_ not modelled 44.6 18 PDB header:oxidoreductase Chain: B: PDB Molecule:enoyl-acyl carrier reductase; PDBTitle: synthesis, biological activity, and x-ray crystal structural analysis2 of diaryl ether inhibitors of malarial enoyl acp reductase. 41 c2nq8B_ not modelled 44.6 18 PDB header:oxidoreductase Chain: B: PDB Molecule:enoyl-acyl carrier reductase; PDBTitle: malarial enoyl acyl acp reductase bound with inh-nad adduct 42 c2wtzC_ not modelled 44.6 14 PDB header:ligase Chain: C: PDB Molecule:udp-n-acetylmuramoyl-l-alanyl-d-glutamate- PDBTitle: mure ligase of mycobacterium tuberculosis 43 c3ppiA_ not modelled 43.9 22 PDB header:oxidoreductase Chain: A: PDB Molecule:3-hydroxyacyl-coa dehydrogenase type-2; PDBTitle: crystal structure of 3-hydroxyacyl-coa dehydrogenase type-2 from2 mycobacterium avium 44 d2pv7a2 not modelled 42.7 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain 45 d1uh5a_ not modelled 41.9 18 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 46 d1km4a_ not modelled 41.7 17 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Decarboxylase 47 d1rpxa_ not modelled 40.9 15 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 48 c1zcjA_ not modelled 40.7 17 PDB header:oxidoreductase Chain: A: PDB Molecule:peroxisomal bifunctional enzyme; PDBTitle: crystal structure of 3-hydroxyacyl-coa dehydrogenase 49 c3lf2B_ not modelled 40.3 30 PDB header:oxidoreductase Chain: B: PDB Molecule:short chain oxidoreductase q9hya2; PDBTitle: nadph bound structure of the short chain oxidoreductase q9hya2 from2 pseudomonas aeruginosa pao1 containing an atypical catalytic center 50 d1o13a_ not modelled 39.6 7 Fold:Ribonuclease H-like motif Superfamily:Nitrogenase accessory factor-like Family:MTH1175-like 51 c3inpA_ not modelled 39.5 20 PDB header:isomerase Chain: A: PDB Molecule:d-ribulose-phosphate 3-epimerase; PDBTitle: 2.05 angstrom resolution crystal structure of d-ribulose-phosphate 3-2 epimerase from francisella tularensis. 52 c3t4xA_ not modelled 39.0 33 PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase, short chain dehydrogenase/reductase family; PDBTitle: short chain dehydrogenase/reductase family oxidoreductase from2 bacillus anthracis str. ames ancestor 53 d1gega_ not modelled 38.8 20 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 54 d1yxma1 not modelled 38.7 33 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 55 c3l77A_ not modelled 38.6 33 PDB header:oxidoreductase Chain: A: PDB Molecule:short-chain alcohol dehydrogenase; PDBTitle: x-ray structure alcohol dehydrogenase from archaeon thermococcus2 sibiricus complexed with 5-hydroxy-nadp 56 c3dhnA_ not modelled 38.2 17 PDB header:isomerase, lyase Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase; PDBTitle: crystal structure of the putative epimerase q89z24_bactn2 from bacteroides thetaiotaomicron. northeast structural3 genomics consortium target btr310. 57 c3noeA_ not modelled 38.1 17 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from pseudomonas2 aeruginosa 58 c2ehhE_ not modelled 37.8 14 PDB header:lyase Chain: E: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 aquifex aeolicus 59 d2hmva1 not modelled 37.7 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Potassium channel NAD-binding domain 60 d1nu0a_ not modelled 36.3 13 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Putative Holliday junction resolvase RuvX 61 d1fjha_ not modelled 36.3 15 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 62 d1dvja_ not modelled 36.0 16 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Decarboxylase 63 c2ntnB_ not modelled 35.3 33 PDB header:oxidoreductase Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase; PDBTitle: crystal structure of maba-c60v/g139a/s144l 64 c3s55F_ not modelled 34.9 41 PDB header:oxidoreductase Chain: F: PDB Molecule:putative short-chain dehydrogenase/reductase; PDBTitle: crystal structure of a putative short-chain dehydrogenase/reductase2 from mycobacterium abscessus bound to nad 65 d2gv8a1 not modelled 34.2 13 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 66 d1uaya_ not modelled 34.1 30 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 67 c3bmrA_ not modelled 33.7 22 PDB header:oxidoreductase Chain: A: PDB Molecule:pteridine reductase; PDBTitle: structure of pteridine reductase 1 (ptr1) from trypanosoma2 brucei in ternary complex with cofactor (nadp+) and3 inhibitor (compound ax6) 68 c3un1D_ not modelled 33.5 25 PDB header:oxidoreductase Chain: D: PDB Molecule:probable oxidoreductase; PDBTitle: crystal structure of an oxidoreductase from sinorhizobium meliloti2 1021 69 d1vhxa_ not modelled 33.3 13 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Putative Holliday junction resolvase RuvX 70 c2x58B_ not modelled 33.2 17 PDB header:oxidoreductase Chain: B: PDB Molecule:peroxisomal bifunctional enzyme; PDBTitle: the crystal structure of mfe1 liganded with coa 71 c2vdcI_ not modelled 32.9 12 PDB header:oxidoreductase Chain: I: PDB Molecule:glutamate synthase [nadph] small chain; PDBTitle: the 9.5 a resolution structure of glutamate synthase from2 cryo-electron microscopy and its oligomerization behavior3 in solution: functional implications. 72 d2gdza1 not modelled 32.8 30 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 73 c3gk3D_ not modelled 32.5 20 PDB header:oxidoreductase Chain: D: PDB Molecule:acetoacetyl-coa reductase; PDBTitle: crystal structure of acetoacetyl-coa reductase from2 burkholderia pseudomallei 1710b 74 c3g0sA_ not modelled 32.5 12 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: dihydrodipicolinate synthase from salmonella typhimurium lt2 75 c3tfoD_ not modelled 31.9 26 PDB header:oxidoreductase Chain: D: PDB Molecule:putative 3-oxoacyl-(acyl-carrier-protein) reductase; PDBTitle: crystal structure of a putative 3-oxoacyl-(acyl-carrier-protein)2 reductase from sinorhizobium meliloti 76 c3dz1A_ not modelled 31.7 17 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 rhodopseudomonas palustris at 1.87a resolution 77 c2p91A_ not modelled 31.5 26 PDB header:oxidoreductase Chain: A: PDB Molecule:enoyl-[acyl-carrier-protein] reductase [nadh]; PDBTitle: crystal structure of enoyl-[acyl-carrier-protein] reductase (nadh)2 from aquifex aeolicus vf5 78 c2nm0B_ not modelled 31.5 36 PDB header:oxidoreductase Chain: B: PDB Molecule:probable 3-oxacyl-(acyl-carrier-protein) reductase; PDBTitle: crystal structure of sco1815: a beta-ketoacyl-acyl carrier protein2 reductase from streptomyces coelicolor a3(2) 79 d1xq1a_ not modelled 31.5 30 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 80 c3k6jA_ not modelled 31.2 24 PDB header:oxidoreductase Chain: A: PDB Molecule:protein f01g10.3, confirmed by transcript evidence; PDBTitle: crystal structure of the dehydrogenase part of multifuctional enzyme 12 from c.elegans 81 d2d1ya1 not modelled 30.8 30 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 82 c2pv7B_ not modelled 30.6 17 PDB header:isomerase, oxidoreductase Chain: B: PDB Molecule:t-protein [includes: chorismate mutase (ec 5.4.99.5) (cm) PDBTitle: crystal structure of chorismate mutase / prephenate dehydrogenase2 (tyra) (1574749) from haemophilus influenzae rd at 2.00 a resolution 83 d1xg5a_ not modelled 30.2 30 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 84 c2qhxB_ not modelled 30.0 28 PDB header:oxidoreductase Chain: B: PDB Molecule:pteridine reductase 1; PDBTitle: structure of pteridine reductase from leishmania major2 complexed with a ligand 85 c3i1jB_ not modelled 29.9 33 PDB header:oxidoreductase Chain: B: PDB Molecule:oxidoreductase, short chain PDBTitle: structure of a putative short chain dehydrogenase from2 pseudomonas syringae 86 d1f6ya_ not modelled 29.4 15 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Methyltetrahydrofolate-utiluzing methyltransferases 87 c2vt2A_ not modelled 29.1 18 PDB header:transcription Chain: A: PDB Molecule:redox-sensing transcriptional repressor rex; PDBTitle: structure and functional properties of the bacillus2 subtilis transcriptional repressor rex 88 c3rihB_ not modelled 28.7 33 PDB header:oxidoreductase Chain: B: PDB Molecule:short chain dehydrogenase or reductase; PDBTitle: crystal structure of a putative short chain dehydrogenase or reductase2 from mycobacterium abscessus 89 d1ah4a_ not modelled 28.6 13 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 90 c3f5sA_ not modelled 28.5 33 PDB header:oxidoreductase Chain: A: PDB Molecule:dehydrogenase; PDBTitle: crystal structure of putatitve short chain dehydrogenase from shigella2 flexneri 2a str. 301 91 c3n2xB_ not modelled 28.4 18 PDB header:lyase Chain: B: PDB Molecule:uncharacterized protein yage; PDBTitle: crystal structure of yage, a prophage protein belonging to the2 dihydrodipicolinic acid synthase family from e. coli k12 in complex3 with pyruvate 92 c3uxyC_ not modelled 28.1 30 PDB header:oxidoreductase Chain: C: PDB Molecule:short-chain dehydrogenase/reductase sdr; PDBTitle: the crystal structure of short chain dehydrogenase from rhodobacter2 sphaeroides 93 c3n0vD_ not modelled 28.1 13 PDB header:hydrolase Chain: D: PDB Molecule:formyltetrahydrofolate deformylase; PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (pp_0327)2 from pseudomonas putida kt2440 at 2.25 a resolution 94 d2h7ma1 not modelled 28.1 19 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 95 d1zk4a1 not modelled 28.0 41 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 96 c1zmoF_ not modelled 28.0 15 PDB header:lyase Chain: F: PDB Molecule:halohydrin dehalogenase; PDBTitle: apo structure of haloalcohol dehalogenase hhea of2 arthrobacter sp. ad2 97 d2bela_ not modelled 27.8 26 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 98 d1vqta1 not modelled 27.4 13 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Decarboxylase 99 d1s1pa_ not modelled 27.3 11 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 100 c3louB_ not modelled 27.2 12 PDB header:hydrolase Chain: B: PDB Molecule:formyltetrahydrofolate deformylase; PDBTitle: crystal structure of formyltetrahydrofolate deformylase (yp_105254.1)2 from burkholderia mallei atcc 23344 at 1.90 a resolution 101 c3sc4A_ not modelled 27.0 22 PDB header:oxidoreductase Chain: A: PDB Molecule:short chain dehydrogenase (a0qtm2 homolog); PDBTitle: crystal structure of a short chain dehydrogenase (a0qtm2 homolog)2 mycobacterium thermoresistibile 102 c3qivA_ not modelled 26.8 41 PDB header:oxidoreductase Chain: A: PDB Molecule:short-chain dehydrogenase or 3-oxoacyl-[acyl-carrier- PDBTitle: crystal structure of a putative short-chain dehydrogenase or 3-2 oxoacyl-[acyl-carrier-protein] reductase from mycobacterium3 paratuberculosis atcc baa-968 / k-10 103 c2ydyA_ not modelled 26.7 21 PDB header:oxidoreductase Chain: A: PDB Molecule:methionine adenosyltransferase 2 subunit beta; PDBTitle: crystal structure of human s-adenosylmethionine synthetase2 2, beta subunit in orthorhombic crystal form 104 d1vjda_ not modelled 26.7 15 Fold:Phosphoglycerate kinase Superfamily:Phosphoglycerate kinase Family:Phosphoglycerate kinase 105 c2dknA_ not modelled 26.4 30 PDB header:oxidoreductase Chain: A: PDB Molecule:3-alpha-hydroxysteroid dehydrogenase; PDBTitle: crystal structure of the 3-alpha-hydroxysteroid dehydrogenase from2 pseudomonas sp. b-0831 complexed with nadh 106 c2w1vA_ not modelled 26.1 7 PDB header:hydrolase Chain: A: PDB Molecule:nitrilase homolog 2; PDBTitle: crystal structure of mouse nitrilase-2 at 1.4a resolution 107 d1xcfa_ not modelled 26.1 17 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 108 c3ezlA_ not modelled 26.0 20 PDB header:oxidoreductase Chain: A: PDB Molecule:acetoacetyl-coa reductase; PDBTitle: crystal structure of acetyacetyl-coa reductase from2 burkholderia pseudomallei 1710b 109 c1yb1B_ not modelled 25.8 22 PDB header:oxidoreductase Chain: B: PDB Molecule:17-beta-hydroxysteroid dehydrogenase type xi; PDBTitle: crystal structure of human 17-beta-hydroxysteroid dehydrogenase type2 xi 110 d1xu9a_ not modelled 25.8 14 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 111 c2x7vA_ not modelled 25.7 11 PDB header:hydrolase Chain: A: PDB Molecule:probable endonuclease 4; PDBTitle: crystal structure of thermotoga maritima endonuclease iv in2 the presence of zinc 112 c3tfxB_ not modelled 25.4 19 PDB header:lyase Chain: B: PDB Molecule:orotidine 5'-phosphate decarboxylase; PDBTitle: crystal structure of orotidine 5'-phosphate decarboxylase from2 lactobacillus acidophilus 113 d1o94c_ not modelled 25.3 17 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ETFP subunits 114 d1gtea3 not modelled 25.3 16 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:C-terminal domain of adrenodoxin reductase-like 115 c3rd5A_ not modelled 25.1 30 PDB header:oxidoreductase Chain: A: PDB Molecule:mypaa.01249.c; PDBTitle: crystal structure of a putative uncharacterized protein from2 mycobacterium paratuberculosis 116 c3q2oB_ not modelled 24.8 18 PDB header:lyase Chain: B: PDB Molecule:phosphoribosylaminoimidazole carboxylase, atpase subunit; PDBTitle: crystal structure of purk: n5-carboxyaminoimidazole ribonucleotide2 synthetase 117 d1rd5a_ not modelled 24.7 20 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 118 d1x1ta1 not modelled 24.6 37 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 119 c3uvzB_ not modelled 24.4 22 PDB header:lyase Chain: B: PDB Molecule:phosphoribosylaminoimidazole carboxylase, atpase subunit; PDBTitle: crystal structure of phosphoribosylaminoimidazole carboxylase, atpase2 subunit from burkholderia ambifaria 120 c2hjwA_ not modelled 24.3 16 PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: crystal structure of the bc domain of acc2

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0