Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	I	K	L	G	I	V	M	D	P	I	A	N	I	N	I	K	K	D	S	S	F	A	M	L	L	E	A	Q	R	R	G	Y	E	L	H	Y	M	E	M	G	D	L	Y	L	I	N	G	E	A	R	A	H	T	R	T	L	N	V	K
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Q	N	Y	E	E	W	F	S	F	V	G	E	Q	D	L	P	L	A	D	L	D	V	I	L	M	R	K	D	P	P	F	D	T	E	F	I	Y	A	T	Y	I	L	E	R	A	E	E	K	G	T	L	I	V	N	K	P	Q	S	L	R
Secondary structure
SS confidence
Disorder													?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		D	C	N	E	K	L	F	T	A	W	F	S	D	L	T	P	E	T	L	V	T	R	N	K	A	Q	L	K	A	F	W	E	K	H	S	D	I	I	L	K	P	L	D	G	M	G	G	A	S	I	F	R	V	K	E	G	D	P	N	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		G	V	I	A	E	T	L	T	E	H	G	T	R	Y	C	M	A	Q	N	Y	L	P	A	I	K	D	G	D	K	R	V	L	V	V	D	G	E	P	V	P	Y	C	L	A	R	I	P	Q	G	G	E	T	R	G	N	L	A	A	G	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		R	G	E	P	R	P	L	T	E	S	D	W	K	I	A	R	Q	I	G	P	T	L	K	E	K	G	L	I	F	V	G	L	D	I	I	G	D	R	L	T	E	I	N	V	T	S	P	T	C	I	R	E	I	E	A	E	F	P	V	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.
Sequence		I	T	G	M	L	M	D	A	I	E	A	R	L	Q	Q	Q
Secondary structure
SS confidence
Disorder																?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1gsh chain A Region: 1 - 316 Aligned: 296 Modelled: 300 Confidence: 100.0% Identity: 99% PDB header:glutathione biosynthesis ligase Chain: A: PDB Molecule:glutathione biosynthetic ligase; PDBTitle: structure of escherichia coli glutathione synthetase at ph 7.5 Phyre2 PDB 1gsa chain A domain 2 Region: 123 - 314 Aligned: 192 Modelled: 192 Confidence: 100.0% Identity: 100% Fold: ATP-grasp Superfamily: Glutathione synthetase ATP-binding domain-like Family: ATP-binding domain of peptide synthetases Phyre2 PDB 1uc8 chain B Region: 4 - 313 Aligned: 240 Modelled: 257 Confidence: 100.0% Identity: 22% PDB header:biosynthetic protein Chain: B: PDB Molecule:lysine biosynthesis enzyme; PDBTitle: crystal structure of a lysine biosynthesis enzyme, lysx,2 from thermus thermophilus hb8 Phyre2 PDB 1i7n chain A Region: 80 - 313 Aligned: 225 Modelled: 234 Confidence: 100.0% Identity: 15% PDB header:neuropeptide Chain: A: PDB Molecule:synapsin ii; PDBTitle: crystal structure analysis of the c domain of synapsin ii2 from rat brain Phyre2 PDB 2p0a chain A Region: 79 - 310 Aligned: 223 Modelled: 232 Confidence: 100.0% Identity: 14% PDB header:neuropeptide Chain: A: PDB Molecule:synapsin-3; PDBTitle: the crystal structure of human synapsin iii (syn3) in complex with2 amppnp Phyre2 PDB 1pk8 chain D Region: 80 - 309 Aligned: 221 Modelled: 230 Confidence: 100.0% Identity: 14% PDB header:membrane protein Chain: D: PDB Molecule:rat synapsin i; PDBTitle: crystal structure of rat synapsin i c domain complexed to2 ca.atp Phyre2 PDB 1m6v chain E Region: 3 - 308 Aligned: 295 Modelled: 301 Confidence: 100.0% Identity: 13% PDB header:ligase Chain: E: PDB Molecule:carbamoyl phosphate synthetase large chain; PDBTitle: crystal structure of the g359f (small subunit) point mutant of2 carbamoyl phosphate synthetase Phyre2 PDB 3bg5 chain C Region: 1 - 307 Aligned: 292 Modelled: 299 Confidence: 100.0% Identity: 15% PDB header:ligase Chain: C: PDB Molecule:pyruvate carboxylase; PDBTitle: crystal structure of staphylococcus aureus pyruvate2 carboxylase Phyre2 PDB 1kjj chain A Region: 3 - 309 Aligned: 279 Modelled: 299 Confidence: 99.9% Identity: 11% PDB header:transferase Chain: A: PDB Molecule:phosphoribosylglycinamide formyltransferase 2; PDBTitle: crystal structure of glycniamide ribonucleotide2 transformylase in complex with mg-atp-gamma-s Phyre2 PDB 3ln6 chain A Region: 20 - 309 Aligned: 232 Modelled: 241 Confidence: 99.9% Identity: 19% PDB header:ligase Chain: A: PDB Molecule:glutathione biosynthesis bifunctional protein gshab; PDBTitle: crystal structure of a bifunctional glutathione synthetase from2 streptococcus agalactiae Phyre2 PDB 2qb5 chain B Region: 1 - 316 Aligned: 267 Modelled: 282 Confidence: 99.9% Identity: 17% PDB header:transferase Chain: B: PDB Molecule:inositol-tetrakisphosphate 1-kinase; PDBTitle: crystal structure of human inositol 1,3,4-trisphosphate 5/6-kinase2 (itpk1) in complex with adp and mn2+ Phyre2 PDB 3i12 chain A Region: 2 - 316 Aligned: 308 Modelled: 310 Confidence: 99.9% Identity: 13% PDB header:ligase Chain: A: PDB Molecule:d-alanine-d-alanine ligase a; PDBTitle: the crystal structure of the d-alanyl-alanine synthetase a from2 salmonella enterica subsp. enterica serovar typhimurium str. lt2 Phyre2 PDB 1gsa chain A domain 1 Region: 1 - 122 Aligned: 122 Modelled: 122 Confidence: 99.9% Identity: 100% Fold: PreATP-grasp domain Superfamily: PreATP-grasp domain Family: Prokaryotic glutathione synthetase, N-terminal domain Phyre2 PDB 1w96 chain B Region: 10 - 308 Aligned: 292 Modelled: 299 Confidence: 99.9% Identity: 12% PDB header:ligase Chain: B: PDB Molecule:acetyl-coenzyme a carboxylase; PDBTitle: crystal structure of biotin carboxylase domain of acetyl-2 coenzyme a carboxylase from saccharomyces cerevisiae in3 complex with soraphen a Phyre2 PDB 3ln7 chain A Region: 20 - 309 Aligned: 228 Modelled: 239 Confidence: 99.9% Identity: 21% PDB header:ligase Chain: A: PDB Molecule:glutathione biosynthesis bifunctional protein gshab; PDBTitle: crystal structure of a bifunctional glutathione synthetase from2 pasteurella multocida Phyre2 PDB 3g8c chain B Region: 1 - 308 Aligned: 294 Modelled: 299 Confidence: 99.9% Identity: 13% PDB header:ligase Chain: B: PDB Molecule:biotin carboxylase; PDBTitle: crystal stucture of biotin carboxylase in complex with2 biotin, bicarbonate, adp and mg ion Phyre2 PDB 2xd4 chain A Region: 2 - 309 Aligned: 283 Modelled: 302 Confidence: 99.9% Identity: 15% PDB header:ligase Chain: A: PDB Molecule:phosphoribosylamine--glycine ligase; PDBTitle: nucleotide-bound structures of bacillus subtilis glycinamide2 ribonucleotide synthetase Phyre2 PDB 2dzd chain B Region: 1 - 308 Aligned: 291 Modelled: 293 Confidence: 99.9% Identity: 14% PDB header:ligase Chain: B: PDB Molecule:pyruvate carboxylase; PDBTitle: crystal structure of the biotin carboxylase domain of2 pyruvate carboxylase Phyre2 PDB 2yya chain B Region: 2 - 310 Aligned: 284 Modelled: 296 Confidence: 99.9% Identity: 18% PDB header:ligase Chain: B: PDB Molecule:phosphoribosylamine--glycine ligase; PDBTitle: crystal structure of gar synthetase from aquifex aeolicus Phyre2 PDB 2hjw chain A Region: 10 - 308 Aligned: 292 Modelled: 299 Confidence: 99.9% Identity: 12% PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: crystal structure of the bc domain of acc2 Phyre2 1 c1gshA_ 2 d1gsaa2 3 c1uc8B_ 4 c1i7nA_ 5 c2p0aA_ 6 c1pk8D_ 7 c1m6vE_ 8 c3bg5C_ 9 c1kjjA_ 10 c3ln6A_ 11 c2qb5B_ 12 c3i12A_ 13 d1gsaa1 14 c1w96B_ 15 c3ln7A_ 16 c3g8cB_ 17 c2xd4A_ 18 c2dzdB_ 19 c2yyaB_ 20 c2hjwA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1gshA_ 100.0 99 PDB header:glutathione biosynthesis ligase Chain: A: PDB Molecule:glutathione biosynthetic ligase; PDBTitle: structure of escherichia coli glutathione synthetase at ph 7.5 2 d1gsaa2 100.0 100 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:ATP-binding domain of peptide synthetases 3 c1uc8B_ 100.0 22 PDB header:biosynthetic protein Chain: B: PDB Molecule:lysine biosynthesis enzyme; PDBTitle: crystal structure of a lysine biosynthesis enzyme, lysx,2 from thermus thermophilus hb8 4 c1i7nA_ 100.0 15 PDB header:neuropeptide Chain: A: PDB Molecule:synapsin ii; PDBTitle: crystal structure analysis of the c domain of synapsin ii2 from rat brain 5 c2p0aA_ 100.0 14 PDB header:neuropeptide Chain: A: PDB Molecule:synapsin-3; PDBTitle: the crystal structure of human synapsin iii (syn3) in complex with2 amppnp 6 c1pk8D_ 100.0 14 PDB header:membrane protein Chain: D: PDB Molecule:rat synapsin i; PDBTitle: crystal structure of rat synapsin i c domain complexed to2 ca.atp 7 c1m6vE_ 100.0 13 PDB header:ligase Chain: E: PDB Molecule:carbamoyl phosphate synthetase large chain; PDBTitle: crystal structure of the g359f (small subunit) point mutant of2 carbamoyl phosphate synthetase 8 c3bg5C_ 100.0 15 PDB header:ligase Chain: C: PDB Molecule:pyruvate carboxylase; PDBTitle: crystal structure of staphylococcus aureus pyruvate2 carboxylase 9 c1kjjA_ 99.9 11 PDB header:transferase Chain: A: PDB Molecule:phosphoribosylglycinamide formyltransferase 2; PDBTitle: crystal structure of glycniamide ribonucleotide2 transformylase in complex with mg-atp-gamma-s 10 c3ln6A_ 99.9 19 PDB header:ligase Chain: A: PDB Molecule:glutathione biosynthesis bifunctional protein gshab; PDBTitle: crystal structure of a bifunctional glutathione synthetase from2 streptococcus agalactiae 11 c2qb5B_ 99.9 17 PDB header:transferase Chain: B: PDB Molecule:inositol-tetrakisphosphate 1-kinase; PDBTitle: crystal structure of human inositol 1,3,4-trisphosphate 5/6-kinase2 (itpk1) in complex with adp and mn2+ 12 c3i12A_ 99.9 13 PDB header:ligase Chain: A: PDB Molecule:d-alanine-d-alanine ligase a; PDBTitle: the crystal structure of the d-alanyl-alanine synthetase a from2 salmonella enterica subsp. enterica serovar typhimurium str. lt2 13 d1gsaa1 99.9 100 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:Prokaryotic glutathione synthetase, N-terminal domain 14 c1w96B_ 99.9 12 PDB header:ligase Chain: B: PDB Molecule:acetyl-coenzyme a carboxylase; PDBTitle: crystal structure of biotin carboxylase domain of acetyl-2 coenzyme a carboxylase from saccharomyces cerevisiae in3 complex with soraphen a 15 c3ln7A_ 99.9 21 PDB header:ligase Chain: A: PDB Molecule:glutathione biosynthesis bifunctional protein gshab; PDBTitle: crystal structure of a bifunctional glutathione synthetase from2 pasteurella multocida 16 c3g8cB_ 99.9 13 PDB header:ligase Chain: B: PDB Molecule:biotin carboxylase; PDBTitle: crystal stucture of biotin carboxylase in complex with2 biotin, bicarbonate, adp and mg ion 17 c2xd4A_ 99.9 15 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylamine--glycine ligase; PDBTitle: nucleotide-bound structures of bacillus subtilis glycinamide2 ribonucleotide synthetase 18 c2dzdB_ 99.9 14 PDB header:ligase Chain: B: PDB Molecule:pyruvate carboxylase; PDBTitle: crystal structure of the biotin carboxylase domain of2 pyruvate carboxylase 19 c2yyaB_ 99.9 18 PDB header:ligase Chain: B: PDB Molecule:phosphoribosylamine--glycine ligase; PDBTitle: crystal structure of gar synthetase from aquifex aeolicus 20 c2hjwA_ 99.9 12 PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: crystal structure of the bc domain of acc2 21 c3ouzA_ not modelled 99.9 11 PDB header:ligase Chain: A: PDB Molecule:biotin carboxylase; PDBTitle: crystal structure of biotin carboxylase-adp complex from campylobacter2 jejuni 22 c1vkzA_ not modelled 99.9 15 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylamine--glycine ligase; PDBTitle: crystal structure of phosphoribosylamine--glycine ligase (tm1250) from2 thermotoga maritima at 2.30 a resolution 23 c1ulzA_ not modelled 99.9 15 PDB header:ligase Chain: A: PDB Molecule:pyruvate carboxylase n-terminal domain; PDBTitle: crystal structure of the biotin carboxylase subunit of pyruvate2 carboxylase 24 c3lp8A_ not modelled 99.9 16 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylamine-glycine ligase; PDBTitle: crystal structure of phosphoribosylamine-glycine ligase from2 ehrlichia chaffeensis 25 c2dlnA_ not modelled 99.9 14 PDB header:ligase(peptidoglycan synthesis) Chain: A: PDB Molecule:d-alanine--d-alanine ligase; PDBTitle: vancomycin resistance: structure of d-alanine:d-alanine2 ligase at 2.3 angstroms resolution 26 c3se7A_ not modelled 99.9 15 PDB header:ligase Chain: A: PDB Molecule:vana; PDBTitle: ancient vana 27 c2vpqA_ not modelled 99.9 10 PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase; PDBTitle: crystal structure of biotin carboxylase from s. aureus2 complexed with amppnp 28 c3tqtB_ not modelled 99.9 13 PDB header:ligase Chain: B: PDB Molecule:d-alanine--d-alanine ligase; PDBTitle: structure of the d-alanine-d-alanine ligase from coxiella burnetii 29 c3e5nA_ not modelled 99.9 14 PDB header:ligase Chain: A: PDB Molecule:d-alanine-d-alanine ligase a; PDBTitle: crystal strucutre of d-alanine-d-alanine ligase from2 xanthomonas oryzae pv. oryzae kacc10331 30 c3lwbA_ not modelled 99.9 18 PDB header:ligase Chain: A: PDB Molecule:d-alanine--d-alanine ligase; PDBTitle: crystal structure of apo d-alanine:d-alanine ligase (ddl) from2 mycobacterium tuberculosis 31 c3t9aA_ not modelled 99.9 16 PDB header:transferase Chain: A: PDB Molecule:inositol pyrophosphate kinase; PDBTitle: crystal structure of the catalytic domain of human diphosphoinositol2 pentakisphosphate kinase 2 (ppip5k2) in complex with amppnp at ph 7.0 32 c2pvpB_ not modelled 99.9 11 PDB header:ligase Chain: B: PDB Molecule:d-alanine-d-alanine ligase; PDBTitle: crystal structure of d-alanine-d-alanine ligase from helicobacter2 pylori 33 c2i80B_ not modelled 99.9 15 PDB header:ligase Chain: B: PDB Molecule:d-alanine-d-alanine ligase; PDBTitle: allosteric inhibition of staphylococcus aureus d-alanine:d-alanine2 ligase revealed by crystallographic studies 34 c2ip4A_ not modelled 99.9 15 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylamine--glycine ligase; PDBTitle: crystal structure of glycinamide ribonucleotide synthetase from2 thermus thermophilus hb8 35 c1e4eB_ not modelled 99.9 15 PDB header:ligase Chain: B: PDB Molecule:vancomycin/teicoplanin a-type resistance protein vana; PDBTitle: d-alanyl-d-lacate ligase 36 c1ehiB_ not modelled 99.9 11 PDB header:ligase Chain: B: PDB Molecule:d-alanine:d-lactate ligase; PDBTitle: d-alanine:d-lactate ligase (lmddl2) of vancomycin-resistant2 leuconostoc mesenteroides 37 c3etjB_ not modelled 99.9 10 PDB header:lyase Chain: B: PDB Molecule:phosphoribosylaminoimidazole carboxylase atpase PDBTitle: crystal structure e. coli purk in complex with mg, adp, and2 pi 38 c2zdqA_ not modelled 99.9 12 PDB header:ligase Chain: A: PDB Molecule:d-alanine--d-alanine ligase; PDBTitle: crystal structure of d-alanine:d-alanine ligase with atp2 and d-alanine:d-alanine from thermus thermophius hb8 39 c2ys6A_ not modelled 99.9 14 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylglycinamide synthetase; PDBTitle: crystal structure of gar synthetase from geobacillus kaustophilus 40 c3orqA_ not modelled 99.9 14 PDB header:ligase,biosynthetic protein Chain: A: PDB Molecule:n5-carboxyaminoimidazole ribonucleotide synthetase; PDBTitle: crystal structure of n5-carboxyaminoimidazole synthetase from2 staphylococcus aureus complexed with adp 41 c3uvzB_ not modelled 99.9 15 PDB header:lyase Chain: B: PDB Molecule:phosphoribosylaminoimidazole carboxylase, atpase subunit; PDBTitle: crystal structure of phosphoribosylaminoimidazole carboxylase, atpase2 subunit from burkholderia ambifaria 42 d1pk8a2 not modelled 99.9 15 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:Synapsin C-terminal domain 43 c3gidB_ not modelled 99.9 12 PDB header:ligase Chain: B: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: the biotin carboxylase (bc) domain of human acetyl-coa2 carboxylase 2 (acc2) in complex with soraphen a 44 c3r23B_ not modelled 99.9 15 PDB header:ligase Chain: B: PDB Molecule:d-alanine--d-alanine ligase; PDBTitle: crystal structure of d-alanine--d-alanine ligase from bacillus2 anthracis 45 d1i7na2 not modelled 99.9 15 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:Synapsin C-terminal domain 46 c3q2oB_ not modelled 99.9 15 PDB header:lyase Chain: B: PDB Molecule:phosphoribosylaminoimidazole carboxylase, atpase subunit; PDBTitle: crystal structure of purk: n5-carboxyaminoimidazole ribonucleotide2 synthetase 47 c3u9sE_ not modelled 99.9 12 PDB header:ligase Chain: E: PDB Molecule:methylcrotonyl-coa carboxylase, alpha-subunit; PDBTitle: crystal structure of p. aeruginosa 3-methylcrotonyl-coa carboxylase2 (mcc) 750 kd holoenzyme, coa complex 48 d1uc8a2 not modelled 99.9 20 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:Lysine biosynthesis enzyme LysX ATP-binding domain 49 c3k3pA_ not modelled 99.9 12 PDB header:ligase Chain: A: PDB Molecule:d-alanine--d-alanine ligase; PDBTitle: crystal structure of the apo form of d-alanine:d-alanine ligase (ddl)2 from streptococcus mutans 50 c2gpwC_ not modelled 99.9 12 PDB header:ligase Chain: C: PDB Molecule:biotin carboxylase; PDBTitle: crystal structure of the biotin carboxylase subunit, f363a2 mutant, of acetyl-coa carboxylase from escherichia coli. 51 c2dwcB_ not modelled 99.9 14 PDB header:transferase Chain: B: PDB Molecule:433aa long hypothetical phosphoribosylglycinamide formyl PDBTitle: crystal structure of probable phosphoribosylglycinamide formyl2 transferase from pyrococcus horikoshii ot3 complexed with adp 52 c1gsoA_ not modelled 99.9 13 PDB header:ligase Chain: A: PDB Molecule:protein (glycinamide ribonucleotide synthetase); PDBTitle: glycinamide ribonucleotide synthetase (gar-syn) from e.2 coli. 53 c2qk4A_ not modelled 99.9 11 PDB header:ligase Chain: A: PDB Molecule:trifunctional purine biosynthetic protein adenosine-3; PDBTitle: human glycinamide ribonucleotide synthetase 54 c1z2pX_ not modelled 99.9 12 PDB header:transferase Chain: X: PDB Molecule:inositol 1,3,4-trisphosphate 5/6-kinase; PDBTitle: inositol 1,3,4-trisphosphate 5/6-kinase in complex with mg2+/amp-2 pcp/ins(1,3,4)p3 55 c3k5iB_ not modelled 99.8 16 PDB header:lyase Chain: B: PDB Molecule:phosphoribosyl-aminoimidazole carboxylase; PDBTitle: crystal structure of n5-carboxyaminoimidazole synthase from2 aspergillus clavatus in complex with adp and 5-3 aminoimadazole ribonucleotide 56 c3n6rK_ not modelled 99.8 10 PDB header:ligase Chain: K: PDB Molecule:propionyl-coa carboxylase, alpha subunit; PDBTitle: crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc) 57 d1vkza3 not modelled 99.8 14 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 58 c3df7A_ not modelled 99.8 20 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative atp-grasp superfamily protein; PDBTitle: crystal structure of a putative atp-grasp superfamily2 protein from archaeoglobus fulgidus 59 d1a9xa5 not modelled 99.8 12 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 60 d1w96a3 not modelled 99.8 12 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 61 c2pn1A_ not modelled 99.8 16 PDB header:ligase Chain: A: PDB Molecule:carbamoylphosphate synthase large subunit; PDBTitle: crystal structure of carbamoylphosphate synthase large subunit (split2 gene in mj) (zp_00538348.1) from exiguobacterium sp. 255-15 at 2.00 a3 resolution 62 d3etja3 not modelled 99.7 10 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 63 d1iowa2 not modelled 99.7 13 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:ATP-binding domain of peptide synthetases 64 d1kjqa3 not modelled 99.7 11 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 65 d2j9ga3 not modelled 99.7 14 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 66 d1ehia2 not modelled 99.7 14 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:ATP-binding domain of peptide synthetases 67 c2r85B_ not modelled 99.7 16 PDB header:unknown function Chain: B: PDB Molecule:purp protein pf1517; PDBTitle: crystal structure of purp from pyrococcus furiosus complexed with amp 68 d1ulza3 not modelled 99.7 14 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 69 d1e4ea2 not modelled 99.7 17 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:ATP-binding domain of peptide synthetases 70 d1a9xa6 not modelled 99.6 9 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 71 c2z04A_ not modelled 99.6 16 PDB header:lyase Chain: A: PDB Molecule:phosphoribosylaminoimidazole carboxylase atpase PDBTitle: crystal structure of phosphoribosylaminoimidazole2 carboxylase atpase subunit from aquifex aeolicus 72 d1gsoa3 not modelled 99.5 13 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 73 d2r7ka2 not modelled 99.4 11 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:PurP ATP-binding domain-like 74 d2r85a2 not modelled 99.4 15 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:PurP ATP-binding domain-like 75 c2qf7A_ not modelled 99.4 17 PDB header:ligase Chain: A: PDB Molecule:pyruvate carboxylase protein; PDBTitle: crystal structure of a complete multifunctional pyruvate carboxylase2 from rhizobium etli 76 c2cqyA_ not modelled 98.7 10 PDB header:ligase Chain: A: PDB Molecule:propionyl-coa carboxylase alpha chain, PDBTitle: solution structure of b domain from human propionyl-coa2 carboxylase alpha subunit 77 c3n6xA_ not modelled 98.3 19 PDB header:ligase Chain: A: PDB Molecule:putative glutathionylspermidine synthase; PDBTitle: crystal structure of a putative glutathionylspermidine synthase2 (mfla_0391) from methylobacillus flagellatus kt at 2.35 a resolution 78 c3tinA_ not modelled 98.2 21 PDB header:ligase Chain: A: PDB Molecule:ttl protein; PDBTitle: tubulin tyrosine ligase 79 c1wr2A_ not modelled 97.8 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein ph1789; PDBTitle: crystal structure of ph1788 from pyrococcus horikoshii ot3 80 c2ioaA_ not modelled 97.8 17 PDB header:ligase, hydrolase Chain: A: PDB Molecule:bifunctional glutathionylspermidine PDBTitle: e. coli bifunctional glutathionylspermidine2 synthetase/amidase incomplex with mg2+ and adp and3 phosphinate inhibitor 81 c2nu9E_ not modelled 97.7 14 PDB header:ligase Chain: E: PDB Molecule:succinyl-coa synthetase beta chain; PDBTitle: c123at mutant of e. coli succinyl-coa synthetase2 orthorhombic crystal form 82 d1uc8a1 not modelled 97.7 21 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:Lysine biosynthesis enzyme LysX, N-terminal domain 83 d1eucb2 not modelled 97.6 12 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:Succinyl-CoA synthetase, beta-chain, N-terminal domain 84 c1eucB_ not modelled 97.4 13 PDB header:ligase Chain: B: PDB Molecule:succinyl-coa synthetase, beta chain; PDBTitle: crystal structure of dephosphorylated pig heart, gtp-2 specific succinyl-coa synthetase 85 d2nu7b2 not modelled 97.3 14 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:Succinyl-CoA synthetase, beta-chain, N-terminal domain 86 d1a9xa4 not modelled 96.0 8 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like 87 c3k1tA_ not modelled 95.9 17 PDB header:ligase Chain: A: PDB Molecule:glutamate--cysteine ligase gsha; PDBTitle: crystal structure of putative gamma-glutamylcysteine synthetase2 (yp_546622.1) from methylobacillus flagellatus kt at 1.90 a3 resolution 88 c3mwdA_ not modelled 94.8 13 PDB header:transferase Chain: A: PDB Molecule:atp-citrate synthase; PDBTitle: truncated human atp-citrate lyase with citrate bound 89 d1w96a2 not modelled 94.7 16 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like 90 d1iowa1 not modelled 94.6 12 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:D-Alanine ligase N-terminal domain 91 d2io8a3 not modelled 94.5 20 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:Glutathionylspermidine synthase ATP-binding domain-like 92 d2j9ga2 not modelled 94.3 14 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like 93 c2vpmB_ not modelled 94.1 13 PDB header:ligase Chain: B: PDB Molecule:trypanothione synthetase; PDBTitle: trypanothione synthetase 94 d1kjqa2 not modelled 93.5 13 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like 95 d1ulza2 not modelled 93.5 9 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like 96 c2r7mA_ not modelled 90.0 13 PDB header:ligase Chain: A: PDB Molecule:5-formaminoimidazole-4-carboxamide-1-(beta)-d- PDBTitle: crystal structure of faicar synthetase (purp) from m.2 jannaschii complexed with amp 97 c2qzsA_ not modelled 89.2 13 PDB header:transferase Chain: A: PDB Molecule:glycogen synthase; PDBTitle: crystal structure of wild-type e.coli gs in complex with adp2 and glucose(wtgsb) 98 c2p6pB_ not modelled 88.6 11 PDB header:transferase Chain: B: PDB Molecule:glycosyl transferase; PDBTitle: x-ray crystal structure of c-c bond-forming dtdp-d-olivose-transferase2 urdgt2 99 c2jjmH_ not modelled 88.1 14 PDB header:transferase Chain: H: PDB Molecule:glycosyl transferase, group 1 family protein; PDBTitle: crystal structure of a family gt4 glycosyltransferase from2 bacillus anthracis orf ba1558. 100 d1iira_ not modelled 86.6 8 Fold:UDP-Glycosyltransferase/glycogen phosphorylase Superfamily:UDP-Glycosyltransferase/glycogen phosphorylase Family:Gtf glycosyltransferase 101 c3ia7A_ not modelled 86.4 15 PDB header:transferase Chain: A: PDB Molecule:calg4; PDBTitle: crystal structure of calg4, the calicheamicin glycosyltransferase 102 d2hy5a1 not modelled 86.4 17 Fold:DsrEFH-like Superfamily:DsrEFH-like Family:DsrEF-like 103 d2d1pa1 not modelled 85.8 20 Fold:DsrEFH-like Superfamily:DsrEFH-like Family:DsrEF-like 104 d1pn3a_ not modelled 85.4 10 Fold:UDP-Glycosyltransferase/glycogen phosphorylase Superfamily:UDP-Glycosyltransferase/glycogen phosphorylase Family:Gtf glycosyltransferase 105 d2bisa1 not modelled 85.3 10 Fold:UDP-Glycosyltransferase/glycogen phosphorylase Superfamily:UDP-Glycosyltransferase/glycogen phosphorylase Family:Glycosyl transferases group 1 106 d1rzua_ not modelled 85.0 15 Fold:UDP-Glycosyltransferase/glycogen phosphorylase Superfamily:UDP-Glycosyltransferase/glycogen phosphorylase Family:Glycosyl transferases group 1 107 d1rrva_ not modelled 85.0 5 Fold:UDP-Glycosyltransferase/glycogen phosphorylase Superfamily:UDP-Glycosyltransferase/glycogen phosphorylase Family:Gtf glycosyltransferase 108 c3dojA_ not modelled 84.2 15 PDB header:oxidoreductase Chain: A: PDB Molecule:dehydrogenase-like protein; PDBTitle: structure of glyoxylate reductase 1 from arabidopsis2 (atglyr1) 109 c2gejA_ not modelled 81.2 10 PDB header:transferase Chain: A: PDB Molecule:phosphatidylinositol mannosyltransferase (pima); PDBTitle: crystal structure of phosphatidylinositol mannosyltransferase (pima)2 from mycobacterium smegmatis in complex with gdp-man 110 c2iv3B_ not modelled 80.7 12 PDB header:transferase Chain: B: PDB Molecule:glycosyltransferase; PDBTitle: crystal structure of avigt4, a glycosyltransferase involved2 in avilamycin a biosynthesis 111 d1js1x1 not modelled 80.3 12 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 112 c2hgsA_ not modelled 79.5 12 PDB header:amine/carboxylate ligase Chain: A: PDB Molecule:protein (glutathione synthetase); PDBTitle: human glutathione synthetase 113 d1vlva1 not modelled 79.0 20 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 114 d1t0ia_ not modelled 78.4 14 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:NADPH-dependent FMN reductase 115 c2pbzC_ not modelled 78.3 16 PDB header:ligase Chain: C: PDB Molecule:hypothetical protein; PDBTitle: crystal structure of an imp biosynthesis protein purp from2 thermococcus kodakaraensis 116 c2r60A_ not modelled 76.5 10 PDB header:transferase Chain: A: PDB Molecule:glycosyl transferase, group 1; PDBTitle: structure of apo sucrose phosphate synthase (sps) of2 halothermothrix orenii 117 d1otha1 not modelled 75.5 19 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 118 d1pvva1 not modelled 75.4 17 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 119 c2iyaB_ not modelled 75.0 16 PDB header:transferase Chain: B: PDB Molecule:oleandomycin glycosyltransferase; PDBTitle: the crystal structure of macrolide glycosyltransferases: a2 blueprint for antibiotic engineering 120 c3kalB_ not modelled 74.9 16 PDB header:ligase Chain: B: PDB Molecule:homoglutathione synthetase; PDBTitle: structure of homoglutathione synthetase from glycine max in2 closed conformation with homoglutathione, adp, a sulfate3 ion, and three magnesium ions bound

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0