PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2iyaB_

Fold library id	PDB Header	Molecule	Title
c2iyaB_	PDB header: transferase	Chain: B: PDB Molecule: oleandomycin glycosyltransferase;	PDBTitle: the crystal structure of macrolide glycosyltransferases: a2 blueprint for antibiotic engineering

Links to external resources
Added to library: Tue Mar 16 12:08:52 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence V T P R H I S F F N I P G H G H V N P S L G I V Q E L V A R G H R V S Y A I T D E F A A Q V K A A G A T P V V Y D S I L P K E S N P E E S W

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
T T
T T
S
T T
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence P E D Q E S A M G L F L D E A V R V L P Q L E D A Y A D D R P D L I V Y D I A S W P A P V L G R K W D I P F V Q L S P T F V A Y E G F E E D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S T T S
S T T
T T
S S
T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence V P A V Q D P T A D G L V R F F T R L S A F L E E H G V D T P A T E F L I A P N R C I V A L P R T F Q I K G D T V G D N Y T F V G P T Y G D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S G G G S
T T
T T
S
S S S S
T T T S T T G G G S
T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence R S W E G R P V L L I A L G S A F T D H L D F Y R T C L S A V D G L D W H V V L S V G R F V D P A D L G E V P P N V E V H Q W V P Q L D I L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S
T T
S S
S S S
G G G G
S
T T S S

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence T K A S A F I T H A G M G S T M E A L S N A V P M V A V P Q I A E Q T M N A E R I V E L G L G R H I P R D Q V T A E K L R E A V L A V A S D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S
T T
S S T T S
G G G

. . . . . . . . . 360 . . . . . . . . . 370 . . . . . . . . . 380 . . . .

Sequence P G V A E R L A A V R Q E I R E A G G A R A A A D I L E G I L A E A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	V	T	P	R	H	I	S	F	F	N	I	P	G	H	G	H	V	N	P	S	L	G	I	V	Q	E	L	V	A	R	G	H	R	V	S	Y	A	I	T	D	E	F	A	A	Q	V	K	A	A	G	A	T	P	V	V	Y	D	S	I	L	P	K	E	S	N	P	E	E	S	W
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												S																		T	T																		T	T										S			T	T		T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	P	E	D	Q	E	S	A	M	G	L	F	L	D	E	A	V	R	V	L	P	Q	L	E	D	A	Y	A	D	D	R	P	D	L	I	V	Y	D	I	A	S	W	P	A	P	V	L	G	R	K	W	D	I	P	F	V	Q	L	S	P	T	F	V	A	Y	E	G	F	E	E	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S	S																								T	T	S			S						T	T		T										T								S	S					T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	V	P	A	V	Q	D	P	T	A	D	G	L	V	R	F	F	T	R	L	S	A	F	L	E	E	H	G	V	D	T	P	A	T	E	F	L	I	A	P	N	R	C	I	V	A	L	P	R	T	F	Q	I	K	G	D	T	V	G	D	N	Y	T	F	V	G	P	T	Y	G	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	G	G	G	S		T	T																		T	T			S										S	S				S	S		T	T	T	S	T	T	G	G	G	S		T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	R	S	W	E	G	R	P	V	L	L	I	A	L	G	S	A	F	T	D	H	L	D	F	Y	R	T	C	L	S	A	V	D	G	L	D	W	H	V	V	L	S	V	G	R	F	V	D	P	A	D	L	G	E	V	P	P	N	V	E	V	H	Q	W	V	P	Q	L	D	I	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)															S	S	S															T	T		S	S								S	S	S		G	G	G	G		S			T	T					S	S
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	T	K	A	S	A	F	I	T	H	A	G	M	G	S	T	M	E	A	L	S	N	A	V	P	M	V	A	V	P	Q	I	A	E	Q	T	M	N	A	E	R	I	V	E	L	G	L	G	R	H	I	P	R	D	Q	V	T	A	E	K	L	R	E	A	V	L	A	V	A	S	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T		S																	T	T								S	S													T	T	S						G	G	G
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.
Sequence	P	G	V	A	E	R	L	A	A	V	R	Q	E	I	R	E	A	G	G	A	R	A	A	A	D	I	L	E	G	I	L	A	E	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																T	S