Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	D	I	A	Q	L	L	G	K	D	A	D	N	L	L	Q	H	R	C	M	T	I	P	S	D	Q	L	Y	L	P	G	H	D	Y	V	D	R	V	M	I	D	N	N	R	P	P	A	V	L	R	N	M	Q	T	L	Y	N	T	G
Secondary structure
SS confidence
Disorder		?	?	?																																							?	?	?	?	?	?												?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	L	A	G	T	G	Y	L	S	I	L	P	V	D	Q	G	V	E	H	S	A	G	A	S	F	A	A	N	P	L	Y	F	D	P	K	N	I	V	E	L	A	I	E	A	G	C	N	C	V	A	S	T	Y	G	V	L	A	S	V	S
Secondary structure
SS confidence
Disorder		?	?																				?	?	?	?	?	?	?																														?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		R	R	Y	A	H	R	I	P	F	L	V	K	L	N	H	N	E	T	L	S	Y	P	N	T	Y	D	Q	T	L	Y	A	S	V	E	Q	A	F	N	M	G	A	V	A	V	G	A	T	I	Y	F	G	S	E	E	S	R	R	Q	I	E
Secondary structure
SS confidence
Disorder		?	?														?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		E	I	S	A	A	F	E	R	A	H	E	L	G	M	V	T	V	L	W	A	Y	L	R	N	S	A	F	K	K	D	G	V	D	Y	H	V	S	A	D	L	T	G	Q	A	N	H	L	A	A	T	I	G	A	D	I	V	K	Q	K	M
Secondary structure
SS confidence
Disorder																							?	?		?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		A	E	N	N	G	G	Y	K	A	I	N	Y	G	Y	T	D	D	R	V	Y	S	K	L	T	S	E	N	P	I	D	L	V	R	Y	Q	L	A	N	C	Y	M	G	R	A	G	L	I	N	S	G	G	A	A	G	G	E	T	D	L	S
Secondary structure
SS confidence
Disorder																		?	?		?	?	?			?	?							?	?	?	?	?	?	?	?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence		D	A	V	R	T	A	V	I	N	K	R	A	G	G	M	G	L	I	L	G	R	K	A	F	K	K	S	M	A	D	G	V	K	L	I	N	A	V	Q	D	V	Y	L	D	S	K	I	T	I	A
Secondary structure
SS confidence
Disorder										?																																			?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2qjh chain H Region: 40 - 346 Aligned: 253 Modelled: 273 Confidence: 100.0% Identity: 23% PDB header:lyase Chain: H: PDB Molecule:putative aldolase mj0400; PDBTitle: m. jannaschii adh synthase covalently bound to2 dihydroxyacetone phosphate Phyre2 PDB 3gnd chain C Region: 47 - 346 Aligned: 240 Modelled: 272 Confidence: 100.0% Identity: 22% PDB header:lyase Chain: C: PDB Molecule:aldolase lsrf; PDBTitle: crystal structure of e. coli lsrf in complex with ribulose-5-phosphate Phyre2 PDB 3fok chain H Region: 61 - 344 Aligned: 247 Modelled: 247 Confidence: 100.0% Identity: 16% PDB header:structural genomics, unknown function Chain: H: PDB Molecule:uncharacterized protein cgl0159; PDBTitle: crystal structure of cgl0159 from corynebacterium2 glutamicum (brevibacterium flavum). northeast structural3 genomics target cgr115 Phyre2 PDB 1ojx chain A Region: 49 - 342 Aligned: 248 Modelled: 267 Confidence: 100.0% Identity: 29% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 1to3 chain A Region: 61 - 348 Aligned: 249 Modelled: 256 Confidence: 100.0% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 3jrk chain G Region: 61 - 341 Aligned: 263 Modelled: 272 Confidence: 100.0% Identity: 14% PDB header:lyase Chain: G: PDB Molecule:tagatose 1,6-diphosphate aldolase 2; PDBTitle: a putative tagatose 1,6-diphosphate aldolase from streptococcus2 pyogenes Phyre2 PDB 1n7k chain A Region: 73 - 325 Aligned: 195 Modelled: 216 Confidence: 99.6% Identity: 21% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 1xi3 chain A Region: 143 - 348 Aligned: 154 Modelled: 178 Confidence: 99.2% Identity: 18% Fold: TIM beta/alpha-barrel Superfamily: Thiamin phosphate synthase Family: Thiamin phosphate synthase Phyre2 PDB 3qja chain A Region: 91 - 340 Aligned: 181 Modelled: 210 Confidence: 99.1% Identity: 18% PDB header:lyase Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase; PDBTitle: crystal structure of the mycobacterium tuberculosis indole-3-glycerol2 phosphate synthase (trpc) in apo form Phyre2 PDB 3o63 chain B Region: 142 - 345 Aligned: 165 Modelled: 176 Confidence: 98.9% Identity: 17% PDB header:transferase Chain: B: PDB Molecule:probable thiamine-phosphate pyrophosphorylase; PDBTitle: crystal structure of thiamin phosphate synthase from mycobacterium2 tuberculosis Phyre2 PDB 3ru6 chain C Region: 153 - 342 Aligned: 146 Modelled: 160 Confidence: 98.9% Identity: 13% PDB header:lyase Chain: C: PDB Molecule:orotidine 5'-phosphate decarboxylase; PDBTitle: 1.8 angstrom resolution crystal structure of orotidine 5'-phosphate2 decarboxylase (pyrf) from campylobacter jejuni subsp. jejuni nctc3 11168 Phyre2 PDB 1i4n chain A Region: 80 - 340 Aligned: 185 Modelled: 211 Confidence: 98.9% Identity: 19% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: Tryptophan biosynthesis enzymes Phyre2 PDB 1pii chain A domain 2 Region: 80 - 339 Aligned: 187 Modelled: 209 Confidence: 98.9% Identity: 18% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: Tryptophan biosynthesis enzymes Phyre2 PDB 1a53 chain A Region: 83 - 329 Aligned: 170 Modelled: 192 Confidence: 98.8% Identity: 21% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: Tryptophan biosynthesis enzymes Phyre2 PDB 1j5t chain A Region: 90 - 340 Aligned: 175 Modelled: 207 Confidence: 98.8% Identity: 17% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: Tryptophan biosynthesis enzymes Phyre2 PDB 2c3z chain A Region: 83 - 329 Aligned: 173 Modelled: 202 Confidence: 98.8% Identity: 20% PDB header:lyase Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase; PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus Phyre2 PDB 3igs chain B Region: 89 - 341 Aligned: 197 Modelled: 219 Confidence: 98.7% Identity: 19% PDB header:isomerase Chain: B: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase 2; PDBTitle: structure of the salmonella enterica n-acetylmannosamine-6-phosphate2 2-epimerase Phyre2 PDB 3f4w chain A Region: 153 - 344 Aligned: 132 Modelled: 150 Confidence: 98.7% Identity: 18% PDB header:synthase, lyase Chain: A: PDB Molecule:putative hexulose 6 phosphate synthase; PDBTitle: the 1.65a crystal structure of 3-hexulose-6-phosphate2 synthase from salmonella typhimurium Phyre2 PDB 1ub3 chain A Region: 93 - 315 Aligned: 170 Modelled: 181 Confidence: 98.7% Identity: 21% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 2tps chain A Region: 142 - 342 Aligned: 163 Modelled: 174 Confidence: 98.6% Identity: 17% Fold: TIM beta/alpha-barrel Superfamily: Thiamin phosphate synthase Family: Thiamin phosphate synthase Phyre2 1 c2qjhH_ 2 c3gndC_ 3 c3fokH_ 4 d1ojxa_ 5 d1to3a_ 6 c3jrkG_ 7 d1n7ka_ 8 d1xi3a_ 9 c3qjaA_ 10 c3o63B_ 11 c3ru6C_ 12 d1i4na_ 13 d1piia2 14 d1a53a_ 15 d1j5ta_ 16 c2c3zA_ 17 c3igsB_ 18 c3f4wA_ 19 d1ub3a_ 20 d2tpsa_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499