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Emailm.sternberg@imperial.ac.uk
DescriptionKCJ11_HUMAN_ATP-sensitive_inward_rectifier_potassium_channel_11_
DateWed Jun 17 23:05:45 BST 2015
Unique Job IDa9ffd763295ff236
SequenceMLSRKGIIPE ... Download FASTA
Job Typenormal
Job Expiry

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:59.656 Y:60.330 Z:113.026
Model (left) based on template c3syaA_
Top template information
PDB header:metal transport
Chain: A: PDB Molecule:g protein-activated inward rectifier potassium channel 2;
PDBTitle: crystal structure of the g protein-gated inward rectifier k+ channel2 girk2 (kir3.2) in complex with sodium and pip2
Confidence and coverage
Confidence:100.0% Coverage: 83%
325 residues ( 83% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
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Sequence analysis 

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Domain analysis [Show] 

Detailed template information [Hide] 

 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3syaA_
100.0 50
PDB header:metal transport
Chain: A: PDB Molecule:g protein-activated inward rectifier potassium channel 2;
PDBTitle: crystal structure of the g protein-gated inward rectifier k+ channel2 girk2 (kir3.2) in complex with sodium and pip2
2c3jycA_
100.0 51
PDB header:metal transport
Chain: A: PDB Molecule:inward-rectifier k+ channel kir2.2;
PDBTitle: crystal structure of the eukaryotic strong inward-rectifier2 k+ channel kir2.2 at 3.1 angstrom resolution
3c2qksA_
100.0 45
PDB header:metal transport
Chain: A: PDB Molecule:kir3.1-prokaryotic kir channel chimera;
PDBTitle: crystal structure of a kir3.1-prokaryotic kir channel chimera
4c1xl6B_
100.0 28
PDB header:metal transport
Chain: B: PDB Molecule:inward rectifier potassium channel;
PDBTitle: intermediate gating structure 2 of the inwardly rectifying k+ channel2 kirbac3.1
5c2xkyI_
100.0 50
PDB header:metal transport
Chain: I: PDB Molecule:inward rectifier potassium channel 2;
PDBTitle: single particle analysis of kir2.1nc_4 in negative stain
6c1p7bB_
100.0 27
PDB header:metal transport
Chain: B: PDB Molecule:integral membrane channel and cytosolic domains;
PDBTitle: crystal structure of an inward rectifier potassium channel
7c2gixC_
100.0 49
PDB header:metal transport
Chain: C: PDB Molecule:inward rectifier potassium channel 2;
PDBTitle: cytoplasmic domain structure of kir2.1 containing2 andersen's mutation r218q and rescue mutation t309k
8d1n9pa_
100.0 48
Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:Cytoplasmic domain of inward rectifier potassium channel
9c2e4fA_
100.0 47
PDB header:transport protein
Chain: A: PDB Molecule:g protein-activated inward rectifier potassium channel 2;
PDBTitle: crystal structure of the cytoplasmic domain of g-protein-gated inward2 rectifier potassium channel kir3.2
10c1u4fD_
100.0 51
PDB header:allergen
Chain: D: PDB Molecule:inward rectifier potassium channel 2;
PDBTitle: crystal structure of cytoplasmic domains of irk1 (kir2.1)2 channel
11d1xl4a1
100.0 30
Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:Cytoplasmic domain of inward rectifier potassium channel
12d1p7ba1
100.0 29
Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:Cytoplasmic domain of inward rectifier potassium channel
13d1xl4a2
99.9 27
Fold:Voltage-gated potassium channels
Superfamily:Voltage-gated potassium channels
Family:Voltage-gated potassium channels
14d1p7ba2
99.9 26
Fold:Voltage-gated potassium channels
Superfamily:Voltage-gated potassium channels
Family:Voltage-gated potassium channels
15d2a9ha1
99.1 15
Fold:Voltage-gated potassium channels
Superfamily:Voltage-gated potassium channels
Family:Voltage-gated potassium channels
16d1f6ga_
99.0 13
Fold:Voltage-gated potassium channels
Superfamily:Voltage-gated potassium channels
Family:Voltage-gated potassium channels
17d1r3jc_
99.0 12
Fold:Voltage-gated potassium channels
Superfamily:Voltage-gated potassium channels
Family:Voltage-gated potassium channels
18c3ifxB_
98.9 17
PDB header:membrane protein
Chain: B: PDB Molecule:voltage-gated potassium channel;
PDBTitle: crystal structure of the spin-labeled kcsa mutant v48r1
19c4h33A_
98.9 16
PDB header:membrane protein
Chain: A: PDB Molecule:lmo2059 protein;
PDBTitle: crystal structure of a voltage-gated k+ channel pore module in a2 closed state in lipid membranes, tetragonal crystal form
20c3lnmD_
98.9 19
PDB header:membrane protein, transport protein
Chain: D: PDB Molecule:f233w mutant of the kv2.1 paddle-kv1.2 chimera;
PDBTitle: f233w mutant of the kv2.1 paddle-kv1.2 chimera channel
21c2a79B_
not modelled 98.8 19
PDB header:membrane protein
Chain: B: PDB Molecule:potassium voltage-gated channel subfamily a
PDBTitle: mammalian shaker kv1.2 potassium channel- beta subunit2 complex
22c2r9rH_
not modelled 98.8 17
PDB header:membrane protein, transport protein
Chain: H: PDB Molecule:paddle chimera voltage gated potassium channel kv1.2-kv2.1;
PDBTitle: shaker family voltage dependent potassium channel (kv1.2-kv2.1 paddle2 chimera channel) in association with beta subunit
23c4chwB_
not modelled 98.7 20
PDB header:transport protein
Chain: B: PDB Molecule:cyclic nucleotide-gated potassium channel mll3241;
PDBTitle: the electron crystallography structure of the camp-free2 potassium channel mlok1
24c2kb1A_
not modelled 98.6 15
PDB header:membrane protein
Chain: A: PDB Molecule:wsk3;
PDBTitle: nmr studies of a channel protein without membrane:2 structure and dynamics of water-solubilized kcsa
25c3behA_
not modelled 98.6 19
PDB header:membrane protein
Chain: A: PDB Molecule:mll3241 protein;
PDBTitle: structure of a bacterial cyclic nucleotide regulated ion channel
26c3e8gB_
not modelled 98.6 10
PDB header:membrane protein
Chain: B: PDB Molecule:potassium channel protein;
PDBTitle: crystal structure of the the open nak channel-na+/ca2+ complex
27c4gx5D_
not modelled 98.5 22
PDB header:transport protein
Chain: D: PDB Molecule:trka domain protein;
PDBTitle: gsuk channel
28c4gx2B_
not modelled 98.5 21
PDB header:transport protein
Chain: B: PDB Molecule:trka domain protein;
PDBTitle: gsuk channel bound to nad
29c3vouB_
not modelled 98.5 12
PDB header:transport protein
Chain: B: PDB Molecule:ion transport 2 domain protein, voltage-gated sodium
PDBTitle: the crystal structure of nak-navsulp chimera channel
30c4bw5D_
not modelled 98.2 17
PDB header:transport protein
Chain: D: PDB Molecule:potassium channel subfamily k member 10;
PDBTitle: crystal structure of human two pore domain potassium ion2 channel trek2 (k2p10.1)
31d1orqc_
not modelled 98.1 15
Fold:Voltage-gated potassium channels
Superfamily:Voltage-gated potassium channels
Family:Voltage-gated potassium channels
32c3um7B_
not modelled 98.0 25
PDB header:metal transport
Chain: B: PDB Molecule:potassium channel subfamily k member 4;
PDBTitle: crystal structure of the human two pore domain k+ ion channel traak2 (k2p4.1)
33c4twkB_
not modelled 98.0 18
PDB header:transport protein
Chain: B: PDB Molecule:potassium channel subfamily k member 2;
PDBTitle: crystal structure of human two pore domain potassium ion channel trek12 (k2p2.1)
34c3ukmB_
not modelled 98.0 16
PDB header:membrane protein
Chain: B: PDB Molecule:potassium channel subfamily k member 1;
PDBTitle: crystal structure of the human two pore domain potassium ion channel2 k2p1 (twik-1)
35d1lnqa2
not modelled 97.6 16
Fold:Voltage-gated potassium channels
Superfamily:Voltage-gated potassium channels
Family:Voltage-gated potassium channels
36d2h8pc1
not modelled 97.0 16
Fold:Voltage-gated potassium channels
Superfamily:Voltage-gated potassium channels
Family:Voltage-gated potassium channels
37c1lnqC_
not modelled 96.0 18
PDB header:metal transport
Chain: C: PDB Molecule:potassium channel related protein;
PDBTitle: crystal structure of mthk at 3.3 a
38c4tlmC_
not modelled 81.5 22
PDB header:signaling protein
Chain: C: PDB Molecule:receptor subunit glun1;
PDBTitle: crystal structure of glun1/glun2b nmda receptor, structure 2
39c4j7cK_
not modelled 50.8 12
PDB header:transport protein
Chain: K: PDB Molecule:ktr system potassium uptake protein b;
PDBTitle: ktrab potassium transporter from bacillus subtilis
40c2zxeB_
not modelled 46.2 15
PDB header:hydrolase/transport protein
Chain: B: PDB Molecule:na+,k+-atpase beta subunit;
PDBTitle: crystal structure of the sodium - potassium pump in the e2.2k+.pi2 state
41c3kdpD_
not modelled 42.4 19
PDB header:hydrolase
Chain: D: PDB Molecule:sodium/potassium-transporting atpase subunit beta-1;
PDBTitle: crystal structure of the sodium-potassium pump
42c2yn9B_
not modelled 42.2 15
PDB header:hydrolase
Chain: B: PDB Molecule:potassium-transporting atpase subunit beta;
PDBTitle: cryo-em structure of gastric h+,k+-atpase with bound rubidium
43c2xzbB_
not modelled 32.5 15
PDB header:hydrolase
Chain: B: PDB Molecule:potassium-transporting atpase subunit beta;
PDBTitle: pig gastric h,k-atpase with bound bef and sch28080
44c2a1sC_
not modelled 29.3 29
PDB header:hydrolase
Chain: C: PDB Molecule:poly(a)-specific ribonuclease parn;
PDBTitle: crystal structure of native parn nuclease domain
45c2hg5D_
not modelled 27.5 7
PDB header:membrane protein
Chain: D: PDB Molecule:kcsa channel;
PDBTitle: cs+ complex of a k channel with an amide to ester substitution in the2 selectivity filter
46c3ixzB_
not modelled 26.1 15
PDB header:hydrolase
Chain: B: PDB Molecule:potassium-transporting atpase subunit beta;
PDBTitle: pig gastric h+/k+-atpase complexed with aluminium fluoride
47c4b0sA_
not modelled 25.1 16
PDB header:hydrolase
Chain: A: PDB Molecule:deamidase-depupylase dop;
PDBTitle: structure of the deamidase-depupylase dop of the2 prokaryotic ubiquitin-like modification pathway in complex3 with atp
48d1hywa_
not modelled 24.6 17
Fold:gpW/XkdW-like
Superfamily:Head-to-tail joining protein W, gpW
Family:Head-to-tail joining protein W, gpW
49c3j5pB_
not modelled 24.1 20
PDB header:transport protein
Chain: B: PDB Molecule:transient receptor potential cation channel subfamily v
PDBTitle: structure of trpv1 ion channel determined by single particle electron2 cryo-microscopy
50c3vcmP_
not modelled 21.1 43
PDB header:hydrolase
Chain: P: PDB Molecule:prorenin;
PDBTitle: crystal structure of human prorenin
51c3d45B_
not modelled 19.3 29
PDB header:hydrolase
Chain: B: PDB Molecule:poly(a)-specific ribonuclease parn;
PDBTitle: crystal structure of mouse parn in complex with m7gpppg
52c3pjzA_
not modelled 19.2 23
PDB header:transport protein
Chain: A: PDB Molecule:potassium uptake protein trkh;
PDBTitle: crystal structure of the potassium transporter trkh from vibrio2 parahaemolyticus
53c3b8eB_
not modelled 16.5 19
PDB header:hydrolase/transport protein
Chain: B: PDB Molecule:sodium/potassium-transporting atpase subunit
PDBTitle: crystal structure of the sodium-potassium pump
54c4ltpC_
not modelled 15.6 11
PDB header:transport protein
Chain: C: PDB Molecule:ion transport protein;
PDBTitle: bacterial sodium channel in high calcium, i222 space group, crystal 2
55c2xznQ_
not modelled 15.3 28
PDB header:ribosome
Chain: Q: PDB Molecule:ribosomal protein s17 containing protein;
PDBTitle: crystal structure of the eukaryotic 40s ribosomal2 subunit in complex with initiation factor 1. this file3 contains the 40s subunit and initiation factor for4 molecule 2
56c1ciiA_
not modelled 14.9 6
PDB header:transmembrane protein
Chain: A: PDB Molecule:colicin ia;
PDBTitle: colicin ia
57d1rh5a_
not modelled 14.4 10
Fold:Preprotein translocase SecY subunit
Superfamily:Preprotein translocase SecY subunit
Family:Preprotein translocase SecY subunit
58c3pjzB_
not modelled 13.5 23
PDB header:transport protein
Chain: B: PDB Molecule:potassium uptake protein trkh;
PDBTitle: crystal structure of the potassium transporter trkh from vibrio2 parahaemolyticus
59c4evxA_
not modelled 12.4 60
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative phage endolysin;
PDBTitle: crystal structure of putative phage endolysin from s. enterica
60c2o4wA_
not modelled 11.2 80
PDB header:hydrolase
Chain: A: PDB Molecule:lysozyme;
PDBTitle: t4 lysozyme circular permutant
61c3a0bX_
not modelled 10.9 38
PDB header:electron transport
Chain: X: PDB Molecule:photosystem ii reaction center protein x;
PDBTitle: crystal structure of br-substituted photosystem ii complex
62c3a0hx_
not modelled 10.9 38
PDB header:electron transport
Chain: X: PDB Molecule:photosystem ii reaction center protein x;
PDBTitle: crystal structure of i-substituted photosystem ii complex
63c3a0hX_
not modelled 10.9 38
PDB header:electron transport
Chain: X: PDB Molecule:photosystem ii reaction center protein x;
PDBTitle: crystal structure of i-substituted photosystem ii complex
64c3a0bx_
not modelled 10.9 38
PDB header:electron transport
Chain: X: PDB Molecule:photosystem ii reaction center protein x;
PDBTitle: crystal structure of br-substituted photosystem ii complex
65d1j2ga2
not modelled 10.7 28
Fold:T-fold
Superfamily:Tetrahydrobiopterin biosynthesis enzymes-like
Family:Urate oxidase (uricase)
66c3zeyE_
not modelled 10.6 34
PDB header:ribosome
Chain: E: PDB Molecule:40s ribosomal proteins s11, putative;
PDBTitle: high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
67c4ainB_
not modelled 10.4 9
PDB header:membrane protein
Chain: B: PDB Molecule:glycine betaine transporter betp;
PDBTitle: crystal structure of betp with asymmetric protomers.
68c2qb0D_
not modelled 10.3 80
PDB header:hydrolase regulator
Chain: D: PDB Molecule:telsam domain - lysozyme chimera;
PDBTitle: structure of the 2tel crystallization module fused to t4 lysozyme with2 an ala-gly-pro linker.
69c2w8aC_
not modelled 10.2 9
PDB header:membrane protein
Chain: C: PDB Molecule:glycine betaine transporter betp;
PDBTitle: crystal structure of the sodium-coupled glycine betaine2 symporter betp from corynebacterium glutamicum with bound3 substrate
70d1lpya_
not modelled 10.1 20
Fold:Lysozyme-like
Superfamily:Lysozyme-like
Family:Phage lysozyme
71d2ibaa2
not modelled 10.0 38
Fold:T-fold
Superfamily:Tetrahydrobiopterin biosynthesis enzymes-like
Family:Urate oxidase (uricase)
72d1p5ca_
not modelled 10.0 80
Fold:Lysozyme-like
Superfamily:Lysozyme-like
Family:Phage lysozyme
73c1s5lx_
not modelled 9.7 38
PDB header:photosynthesis
Chain: X: PDB Molecule:photosystem ii psbx protein;
PDBTitle: architecture of the photosynthetic oxygen evolving center
74d2hjea1
not modelled 9.5 25
Fold:Profilin-like
Superfamily:Sensory domain-like
Family:LuxQ-periplasmic domain-like
75d169la_
not modelled 9.3 31
Fold:Lysozyme-like
Superfamily:Lysozyme-like
Family:Phage lysozyme
76c2anxB_
not modelled 9.1 29
PDB header:hydrolase
Chain: B: PDB Molecule:lysozyme;
PDBTitle: crystal structure of bacteriophage p22 lysozyme mutant l87m
77c3he1F_
not modelled 9.1 50
PDB header:structural genomics, unknown function
Chain: F: PDB Molecule:major exported hcp3 protein;
PDBTitle: secreted protein hcp3 from pseudomonas aeruginosa.
78c2e76G_
not modelled 9.0 21
PDB header:photosynthesis
Chain: G: PDB Molecule:cytochrome b6-f complex subunit 5;
PDBTitle: crystal structure of the cytochrome b6f complex with tridecyl-2 stigmatellin (tds) from m.laminosus
79c3j3aL_
not modelled 9.0 28
PDB header:ribosome
Chain: L: PDB Molecule:40s ribosomal protein s11;
PDBTitle: structure of the human 40s ribosomal proteins
80d1l64a_
not modelled 8.9 80
Fold:Lysozyme-like
Superfamily:Lysozyme-like
Family:Phage lysozyme
81c1r56H_
not modelled 8.7 38
PDB header:oxidoreductase
Chain: H: PDB Molecule:uricase;
PDBTitle: uncomplexed urate oxidase from aspergillus flavus
82c2uwjF_
not modelled 8.5 27
PDB header:chaperone
Chain: F: PDB Molecule:type iii export protein pscf;
PDBTitle: structure of the heterotrimeric complex which regulates2 type iii secretion needle formation
83c4iapB_
not modelled 8.5 80
PDB header:lipid binding protein/ hydrorase
Chain: B: PDB Molecule:lysozyme, oxysterol-binding protein homolog 3;
PDBTitle: crystal structure of ph domain of osh3 from saccharomyces cerevisiae
84d2yzca2
not modelled 8.2 34
Fold:T-fold
Superfamily:Tetrahydrobiopterin biosynthesis enzymes-like
Family:Urate oxidase (uricase)
85c2yxyA_
not modelled 8.1 29
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical conserved protein, gk0453;
PDBTitle: crystarl structure of hypothetical conserved protein, gk0453
86c3rzeA_
not modelled 8.1 14
PDB header:hydrolase
Chain: A: PDB Molecule:histamine h1 receptor, lysozyme chimera;
PDBTitle: structure of the human histamine h1 receptor in complex with doxepin
87c4pkfB_
not modelled 8.1 29
PDB header:lyase
Chain: B: PDB Molecule:tutg;
PDBTitle: benzylsuccinate synthase alpha-beta-gamma complex
88c3wx6A_
not modelled 8.0 21
PDB header:unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of type six secretion system protein
89c3fokH_
not modelled 8.0 10
PDB header:structural genomics, unknown function
Chain: H: PDB Molecule:uncharacterized protein cgl0159;
PDBTitle: crystal structure of cgl0159 from corynebacterium2 glutamicum (brevibacterium flavum). northeast structural3 genomics target cgr115
90d2f2qa1
not modelled 8.0 80
Fold:Lysozyme-like
Superfamily:Lysozyme-like
Family:Phage lysozyme
91d1swya_
not modelled 7.9 31
Fold:Lysozyme-like
Superfamily:Lysozyme-like
Family:Phage lysozyme
92c2bruC_
not modelled 7.8 26
PDB header:oxidoreductase
Chain: C: PDB Molecule:nad(p) transhydrogenase subunit beta;
PDBTitle: complex of the domain i and domain iii of escherichia coli2 transhydrogenase
93d1k28a3
not modelled 7.5 80
Fold:Lysozyme-like
Superfamily:Lysozyme-like
Family:Phage lysozyme
94d1xjua_
not modelled 7.4 60
Fold:Lysozyme-like
Superfamily:Lysozyme-like
Family:Phage lysozyme
95d1e42a1
not modelled 7.3 10
Fold:Immunoglobulin-like beta-sandwich
Superfamily:Clathrin adaptor appendage domain
Family:Alpha-adaptin ear subdomain-like
96c1j2gC_
not modelled 7.3 28
PDB header:oxidoreductase
Chain: C: PDB Molecule:uricase;
PDBTitle: crystal structure of urate oxidase from bacillus sp. tb-90 co-2 crystallized with 8-azaxanthine
97d1d4oa_
not modelled 7.2 22
Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Transhydrogenase domain III (dIII)
98d1pnoa_
not modelled 7.1 26
Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Transhydrogenase domain III (dIII)
99c3uonA_
not modelled 7.1 14
PDB header:signaling protein/antagonist
Chain: A: PDB Molecule:human m2 muscarinic acetylcholine, receptor t4 lysozyme
PDBTitle: structure of the human m2 muscarinic acetylcholine receptor bound to2 an antagonist

Binding site prediction 

The top ranking model of your protein (c3syaA_ 100.0% confidence) has been submitted to the 3DLigandSite server to predict potential binding sites.

Results will appear here when complete

Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below