PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2gixC_

Fold library id	PDB Header	Molecule	Title
c2gixC_	PDB header: metal transport	Chain: C: PDB Molecule: inward rectifier potassium channel 2;	PDBTitle: cytoplasmic domain structure of kir2.1 containing2 andersen's mutation r218q and rescue mutation t309k

Links to external resources
Added to library: Tue Mar 16 12:17:32 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence S H G R S R F V K K D G H C N V Q F I N V G E K R N E T L V F S H N A V I A M R D G K L C L M W R V G N L Q K S H L V E A H V R A Q L L K S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
S B
T T S
B
S
S
S
S
T T S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence R I T S E G E Y I P L D Q I D I N V G F D S G I D R I F L V S P I T I V H E I D E D S P L Y D L S K Q D I D N A D F E I V V I L E G M V E A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
S S G G G T T T B
S S
T T S T T T T
T
T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . .

Sequence T A M T K Q C R S S Y L A N E I L W G H R Y E P V L F E E K H Y Y K V D Y S R F H K T Y E V P N T P L C S A R D L A E K K Y I L S N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T G G G T
S S S G G G T T
T T S
S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	S	H	G	R	S	R	F	V	K	K	D	G	H	C	N	V	Q	F	I	N	V	G	E	K	R	N	E	T	L	V	F	S	H	N	A	V	I	A	M	R	D	G	K	L	C	L	M	W	R	V	G	N	L	Q	K	S	H	L	V	E	A	H	V	R	A	Q	L	L	K	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S	S		S	B		T	T	S		B						S			S			S							S								T	T											S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	R	I	T	S	E	G	E	Y	I	P	L	D	Q	I	D	I	N	V	G	F	D	S	G	I	D	R	I	F	L	V	S	P	I	T	I	V	H	E	I	D	E	D	S	P	L	Y	D	L	S	K	Q	D	I	D	N	A	D	F	E	I	V	V	I	L	E	G	M	V	E	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T	T													S	S	G	G	G	T	T	T	B				S	S										T	T	S	T	T	T	T								T														T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.
Sequence	T	A	M	T	K	Q	C	R	S	S	Y	L	A	N	E	I	L	W	G	H	R	Y	E	P	V	L	F	E	E	K	H	Y	Y	K	V	D	Y	S	R	F	H	K	T	Y	E	V	P	N	T	P	L	C	S	A	R	D	L	A	E	K	K	Y	I	L	S	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T											G	G	G				T											S	S	S					G	G	G	T	T						T	T	S			S