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 Protein Homology/analogY Recognition Engine V 2.0



One 2 One threading

What it is

Sometimes you may have a protein sequence and you want to model it on a specific template of your choosing. Perhaps you have a newly solved structure that's not in the Phyre database or you have some biological information that indicates your chosen template would produce a more accurate model than the one(s) automatically chosen by Phyre.

One to one threading allows you to upload both a sequence you wish modelled AND the template on which to model it.

Results and interpretation

Unlike ordinary Phyre results, one to one threading does not of course produce a list of hits. Instead you will be presented by an alignment view and a model of your protein together with some information on the confidence of the match.

Phyre is for non-commercial use only

Commercial users please contact Michael Sternberg

Please cite: The Phyre2 web portal for protein modeling, prediction and analysis
Kelley LA et al. Nature Protocols 10, 845-858 (2015) [paper] [Citation link]
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Michael Sternberg 
Terms and Conditions

Phyre2 is part of Genome3D