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 Protein Homology/analogY Recognition Engine V 2.0



One 2 One threading

What it is

Sometimes you may have a protein sequence and you want to model it on a specific template of your choosing. Perhaps you have a newly solved structure that's not in the Phyre database or you have some biological information that indicates your chosen template would produce a more accurate model than the one(s) automatically chosen by Phyre.

One to one threading allows you to upload both a sequence you wish modelled AND the template on which to model it.

Results and interpretation

Unlike ordinary Phyre results, one to one threading does not of course produce a list of hits. Instead you will be presented by an alignment view and a model of your protein together with some information on the confidence of the match.

Phyre is now FREE for commercial users!

All images and data generated by Phyre2 are free to use in any publication with acknowledgement

Accessibility Statement
Please cite: The Phyre2 web portal for protein modeling, prediction and analysis
Kelley LA et al. Nature Protocols 10, 845-858 (2015) [paper] [Citation link]
© Structural Bioinformatics Group, Imperial College, London
Michael Sternberg 
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Phyre2 is part of Genome3D