Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0A717
DateThu Jan 5 11:04:30 GMT 2012
Unique Job IDfb5d7b4d4dc42227

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3efhB_
Top template information
PDB header:transferase
Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase 1;
PDBTitle: crystal structure of human phosphoribosyl pyrophosphate2 synthetase 1
Confidence and coverage
Confidence:100.0% Coverage: 97%
304 residues ( 97% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MPDMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTC
Secondary structure 



























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Disorder  ??
?























































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   .........70.........80.........90.........100.........110.........120
Sequence  APTNDNLMELVVMVDALRRASAGRITAVIPYFGYARQDRRVRSARVPITAKVVADFLSSV
Secondary structure 


















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Disorder 






































?????















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   .........130.........140.........150.........160.........170.........180
Sequence  GVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLNLDNPIVVSPDIGGVVRARAI
Secondary structure 

























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   .........190.........200.........210.........220.........230.........240
Sequence  AKLLNDTDMAIIDKRRPRANVSQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERG
Secondary structure 
























SS confidence 



























































Disorder 














??
????

?
?
































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   .........250.........260.........270.........280.........290.........300
Sequence  AKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLSDEIKSLPNVRTLTLSGMLAEAI
Secondary structure 






















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Disorder 





































??????















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   .........310.....
Sequence  RRISNEESISAMFEH
Secondary structure 





SS confidence 














Disorder 






?



???
Disorder confidence 














 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3efh chain B

3D model

Region: 3 - 315
Aligned: 304
Modelled: 313
Confidence: 100.0%
Identity: 49%
PDB header:transferase
Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase 1;
PDBTitle: crystal structure of human phosphoribosyl pyrophosphate2 synthetase 1

Phyre2

PDB 1dkr chain B

3D model

Region: 2 - 313
Aligned: 300
Modelled: 312
Confidence: 100.0%
Identity: 51%
PDB header:transferase
Chain: B: PDB Molecule:phosphoribosyl pyrophosphate synthetase;
PDBTitle: crystal structures of bacillus subtilis phosphoribosylpyrophosphate2 synthetase: molecular basis of allosteric inhibition and activation.

Phyre2

PDB 3dah chain B

3D model

Region: 3 - 313
Aligned: 293
Modelled: 294
Confidence: 100.0%
Identity: 63%
PDB header:transferase
Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase;
PDBTitle: 2.3 a crystal structure of ribose-phosphate pyrophosphokinase from2 burkholderia pseudomallei

Phyre2

PDB 2c4k chain D

3D model

Region: 4 - 313
Aligned: 298
Modelled: 310
Confidence: 100.0%
Identity: 41%
PDB header:regulatory protein
Chain: D: PDB Molecule:phosphoribosyl pyrophosphate synthetase-
PDBTitle: crystal structure of human phosphoribosylpyrophosphate2 synthetase-associated protein 39 (pap39)

Phyre2

PDB 3lpn chain B

3D model

Region: 4 - 304
Aligned: 285
Modelled: 301
Confidence: 100.0%
Identity: 31%
PDB header:transferase
Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase;
PDBTitle: crystal structure of the phosphoribosylpyrophosphate (prpp) synthetase2 from thermoplasma volcanium in complex with an atp analog (ampcpp).

Phyre2

PDB 1u9y chain D

3D model

Region: 4 - 300
Aligned: 274
Modelled: 287
Confidence: 100.0%
Identity: 34%
PDB header:transferase
Chain: D: PDB Molecule:ribose-phosphate pyrophosphokinase;
PDBTitle: crystal structure of phosphoribosyl diphosphate synthase2 from methanocaldococcus jannaschii

Phyre2

PDB 1dku chain A domain 1

3D model

Region: 3 - 162
Aligned: 159
Modelled: 160
Confidence: 100.0%
Identity: 55%
Fold: PRTase-like
Superfamily: PRTase-like
Family: Phosphoribosylpyrophosphate synthetase-like

Phyre2

PDB 1u9y chain A domain 1

3D model

Region: 4 - 159
Aligned: 153
Modelled: 156
Confidence: 100.0%
Identity: 31%
Fold: PRTase-like
Superfamily: PRTase-like
Family: Phosphoribosylpyrophosphate synthetase-like

Phyre2

PDB 2c4k chain A domain 1

3D model

Region: 5 - 159
Aligned: 153
Modelled: 155
Confidence: 100.0%
Identity: 42%
Fold: PRTase-like
Superfamily: PRTase-like
Family: Phosphoribosylpyrophosphate synthetase-like

Phyre2

PDB 2c4k chain A domain 2

3D model

Region: 160 - 313
Aligned: 144
Modelled: 154
Confidence: 100.0%
Identity: 39%
Fold: PRTase-like
Superfamily: PRTase-like
Family: Phosphoribosylpyrophosphate synthetase-like

Phyre2

PDB 1dku chain A domain 2

3D model

Region: 163 - 313
Aligned: 136
Modelled: 151
Confidence: 100.0%
Identity: 48%
Fold: PRTase-like
Superfamily: PRTase-like
Family: Phosphoribosylpyrophosphate synthetase-like

Phyre2

PDB 1u9y chain A domain 2

3D model

Region: 163 - 300
Aligned: 119
Modelled: 138
Confidence: 100.0%
Identity: 36%
Fold: PRTase-like
Superfamily: PRTase-like
Family: Phosphoribosylpyrophosphate synthetase-like

Phyre2

PDB 1wd5 chain A

3D model

Region: 148 - 298
Aligned: 147
Modelled: 151
Confidence: 99.7%
Identity: 27%
Fold: PRTase-like
Superfamily: PRTase-like
Family: Phosphoribosyltransferases (PRTases)

Phyre2

PDB 1zn7 chain A domain 1

3D model

Region: 148 - 273
Aligned: 125
Modelled: 126
Confidence: 99.6%
Identity: 18%
Fold: PRTase-like
Superfamily: PRTase-like
Family: Phosphoribosyltransferases (PRTases)

Phyre2

PDB 3o7m chain D

3D model

Region: 150 - 248
Aligned: 98
Modelled: 99
Confidence: 99.6%
Identity: 18%
PDB header:transferase
Chain: D: PDB Molecule:hypoxanthine phosphoribosyltransferase;
PDBTitle: 1.98 angstrom resolution crystal structure of a hypoxanthine-guanine2 phosphoribosyltransferase (hpt-2) from bacillus anthracis str. 'ames3 ancestor'

Phyre2

PDB 3dez chain A

3D model

Region: 104 - 267
Aligned: 157
Modelled: 164
Confidence: 99.6%
Identity: 18%
PDB header:transferase
Chain: A: PDB Molecule:orotate phosphoribosyltransferase;
PDBTitle: crystal structure of orotate phosphoribosyltransferase from2 streptococcus mutans

Phyre2

PDB 1g9s chain A

3D model

Region: 150 - 248
Aligned: 98
Modelled: 99
Confidence: 99.5%
Identity: 18%
Fold: PRTase-like
Superfamily: PRTase-like
Family: Phosphoribosyltransferases (PRTases)

Phyre2

PDB 2dy0 chain A

3D model

Region: 149 - 266
Aligned: 115
Modelled: 118
Confidence: 99.5%
Identity: 20%
PDB header:transferase
Chain: A: PDB Molecule:adenine phosphoribosyltransferase;
PDBTitle: crystal structure of project jw0458 from escherichia coli

Phyre2

PDB 2yzk chain C

3D model

Region: 113 - 273
Aligned: 148
Modelled: 161
Confidence: 99.5%
Identity: 22%
PDB header:transferase
Chain: C: PDB Molecule:orotate phosphoribosyltransferase;
PDBTitle: crystal structure of orotate phosphoribosyltransferase from2 aeropyrum pernix

Phyre2

PDB 1yfz chain A

3D model

Region: 148 - 248
Aligned: 101
Modelled: 101
Confidence: 99.5%
Identity: 17%
PDB header:transferase
Chain: A: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase;
PDBTitle: novel imp binding in feedback inhibition of hypoxanthine-guanine2 phosphoribosyltransferase from thermoanaerobacter tengcongensis

Phyre2
1

c3efhB_
2

c1dkrB_
3

c3dahB_
4

c2c4kD_
5

c3lpnB_
6

c1u9yD_
7

d1dkua1
8

d1u9ya1
9

d2c4ka1
10

d2c4ka2
11

d1dkua2
12

d1u9ya2
13

d1wd5a_
14

d1zn7a1
15

c3o7mD_
16

c3dezA_
17

d1g9sa_
18

c2dy0A_
19

c2yzkC_
20

c1yfzA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3efhB_



100.0 49 PDB header:transferase
Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase 1;
PDBTitle: crystal structure of human phosphoribosyl pyrophosphate2 synthetase 1
2c1dkrB_



100.0 51 PDB header:transferase
Chain: B: PDB Molecule:phosphoribosyl pyrophosphate synthetase;
PDBTitle: crystal structures of bacillus subtilis phosphoribosylpyrophosphate2 synthetase: molecular basis of allosteric inhibition and activation.
3c3dahB_



100.0 63 PDB header:transferase
Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase;
PDBTitle: 2.3 a crystal structure of ribose-phosphate pyrophosphokinase from2 burkholderia pseudomallei
4c2c4kD_



100.0 41 PDB header:regulatory protein
Chain: D: PDB Molecule:phosphoribosyl pyrophosphate synthetase-
PDBTitle: crystal structure of human phosphoribosylpyrophosphate2 synthetase-associated protein 39 (pap39)
5c3lpnB_



100.0 31 PDB header:transferase
Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase;
PDBTitle: crystal structure of the phosphoribosylpyrophosphate (prpp) synthetase2 from thermoplasma volcanium in complex with an atp analog (ampcpp).
6c1u9yD_



100.0 34 PDB header:transferase
Chain: D: PDB Molecule:ribose-phosphate pyrophosphokinase;
PDBTitle: crystal structure of phosphoribosyl diphosphate synthase2 from methanocaldococcus jannaschii
7d1dkua1



100.0 55 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosylpyrophosphate synthetase-like
8d1u9ya1



100.0 31 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosylpyrophosphate synthetase-like
9d2c4ka1



100.0 42 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosylpyrophosphate synthetase-like
10d2c4ka2



100.0 39 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosylpyrophosphate synthetase-like
11d1dkua2



100.0 48 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosylpyrophosphate synthetase-like
12d1u9ya2



100.0 36 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosylpyrophosphate synthetase-like
13d1wd5a_



99.7 27 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
14d1zn7a1



99.6 18 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
15c3o7mD_



99.6 18 PDB header:transferase
Chain: D: PDB Molecule:hypoxanthine phosphoribosyltransferase;
PDBTitle: 1.98 angstrom resolution crystal structure of a hypoxanthine-guanine2 phosphoribosyltransferase (hpt-2) from bacillus anthracis str. 'ames3 ancestor'
16c3dezA_



99.6 18 PDB header:transferase
Chain: A: PDB Molecule:orotate phosphoribosyltransferase;
PDBTitle: crystal structure of orotate phosphoribosyltransferase from2 streptococcus mutans
17d1g9sa_



99.5 18 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
18c2dy0A_



99.5 20 PDB header:transferase
Chain: A: PDB Molecule:adenine phosphoribosyltransferase;
PDBTitle: crystal structure of project jw0458 from escherichia coli
19c2yzkC_



99.5 22 PDB header:transferase
Chain: C: PDB Molecule:orotate phosphoribosyltransferase;
PDBTitle: crystal structure of orotate phosphoribosyltransferase from2 aeropyrum pernix
20c1yfzA_



99.5 17 PDB header:transferase
Chain: A: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase;
PDBTitle: novel imp binding in feedback inhibition of hypoxanthine-guanine2 phosphoribosyltransferase from thermoanaerobacter tengcongensis
21d1yfza1



not modelled 99.5 17 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
22d1vdma1



not modelled 99.5 27 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
23d1z7ga1



not modelled 99.5 18 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
24d1hgxa_



not modelled 99.5 20 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
25d2aeea1



not modelled 99.5 17 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
26d1ecfa1



not modelled 99.5 20 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
27c3kb8A_



not modelled 99.5 22 PDB header:transferase
Chain: A: PDB Molecule:hypoxanthine phosphoribosyltransferase;
PDBTitle: 2.09 angstrom resolution structure of a hypoxanthine-guanine2 phosphoribosyltransferase (hpt-1) from bacillus anthracis str. 'ames3 ancestor' in complex with gmp
28c2ywtA_



not modelled 99.5 18 PDB header:transferase
Chain: A: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase;
PDBTitle: crystal structure of hypoxanthine-guanine2 phosphoribosyltransferase with gmp from thermus3 thermophilus hb8
29d1j7ja_



not modelled 99.4 20 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
30d1l1qa_



not modelled 99.4 16 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
31d1ufra_



not modelled 99.4 22 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
32d1gph11



not modelled 99.4 19 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
33d1cjba_



not modelled 99.4 22 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
34d1g2qa_



not modelled 99.4 18 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
35d1tc1a_



not modelled 99.4 13 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
36d1p17b_



not modelled 99.4 17 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
37d1y0ba1



not modelled 99.4 11 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
38c2wnsB_



not modelled 99.4 17 PDB header:transferase
Chain: B: PDB Molecule:orotate phosphoribosyltransferase;
PDBTitle: human orotate phosphoribosyltransferase (oprtase) domain of2 uridine 5'-monophosphate synthase (umps) in complex with3 its substrate orotidine 5'-monophosphate (omp)
39d1vcha1



not modelled 99.3 17 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
40d1mzva_



not modelled 99.3 19 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
41d1w30a_



not modelled 99.3 17 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
42d1a3ca_



not modelled 99.3 21 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
43d2igba1



not modelled 99.3 22 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
44d1qb7a_



not modelled 99.3 19 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
45c1ecjB_



not modelled 99.3 18 PDB header:transferase
Chain: B: PDB Molecule:glutamine phosphoribosylpyrophosphate
PDBTitle: escherichia coli glutamine phosphoribosylpyrophosphate2 (prpp) amidotransferase complexed with 2 amp per tetramer
46c2p1zA_



not modelled 99.3 20 PDB header:transferase
Chain: A: PDB Molecule:phosphoribosyltransferase;
PDBTitle: crystal structure of phosphoribosyltransferase from corynebacterium2 diphtheriae
47c1gph1_



not modelled 99.3 22 PDB header:transferase(glutamine amidotransferase)
Chain: 1: PDB Molecule:glutamine phosphoribosyl-pyrophosphate amidotransferase;
PDBTitle: structure of the allosteric regulatory enzyme of purine biosynthesis
48d1pzma_



not modelled 99.2 13 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
49d1o57a2



not modelled 99.2 19 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
50c1pzmB_



not modelled 99.2 13 PDB header:transferase
Chain: B: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase;
PDBTitle: crystal structure of hgprt-ase from leishmania tarentolae in complex2 with gmp
51c3m3hA_



not modelled 99.2 19 PDB header:transferase
Chain: A: PDB Molecule:orotate phosphoribosyltransferase;
PDBTitle: 1.75 angstrom resolution crystal structure of an orotate2 phosphoribosyltransferase from bacillus anthracis str. 'ames3 ancestor'
52d1fsga_



not modelled 99.2 14 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
53d1lh0a_



not modelled 99.2 18 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
54c1o57A_



not modelled 99.1 20 PDB header:dna binding protein
Chain: A: PDB Molecule:pur operon repressor;
PDBTitle: crystal structure of the purine operon repressor of2 bacillus subtilis
55c2jbhA_



not modelled 99.1 17 PDB header:transferase
Chain: A: PDB Molecule:phosphoribosyltransferase domain-containing protein 1;
PDBTitle: human phosphoribosyl transferase domain containing 1
56c3mjdA_



not modelled 99.0 17 PDB header:transferase
Chain: A: PDB Molecule:orotate phosphoribosyltransferase;
PDBTitle: 1.9 angstrom crystal structure of orotate2 phosphoribosyltransferase (pyre) francisella tularensis.
57c2jkzB_



not modelled 99.0 26 PDB header:transferase
Chain: B: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase;
PDBTitle: saccharomyces cerevisiae hypoxanthine-guanine2 phosphoribosyltransferase in complex with gmp (guanosine 5'3 -monophosphate) (orthorhombic crystal form)
58c2przB_



not modelled 99.0 16 PDB header:transferase
Chain: B: PDB Molecule:orotate phosphoribosyltransferase 1;
PDBTitle: s. cerevisiae orotate phosphoribosyltransferase complexed2 with omp
59c3qw4B_



not modelled 98.9 20 PDB header:transferase, lyase
Chain: B: PDB Molecule:ump synthase;
PDBTitle: structure of leishmania donovani ump synthase
60d1o5oa_



not modelled 98.9 26 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
61d1i5ea_



not modelled 98.9 25 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
62c2ehjA_



not modelled 98.9 16 PDB header:transferase
Chain: A: PDB Molecule:uracil phosphoribosyltransferase;
PDBTitle: structure of uracil phosphoribosyl transferase
63c2e55D_



not modelled 98.9 17 PDB header:transferase
Chain: D: PDB Molecule:uracil phosphoribosyltransferase;
PDBTitle: structure of aq2163 protein from aquifex aeolicus
64c3n2lA_



not modelled 98.8 17 PDB header:transferase
Chain: A: PDB Molecule:orotate phosphoribosyltransferase;
PDBTitle: 2.1 angstrom resolution crystal structure of an orotate2 phosphoribosyltransferase (pyre) from vibrio cholerae o1 biovar eltor3 str. n16961
65d1nula_



not modelled 98.8 21 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
66c3dmpD_



not modelled 98.7 17 PDB header:transferase
Chain: D: PDB Molecule:uracil phosphoribosyltransferase;
PDBTitle: 2.6 a crystal structure of uracil phosphoribosyltransferase2 from burkholderia pseudomallei
67d1xtta1



not modelled 98.6 17 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
68d1bd3a_



not modelled 98.6 18 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
69d1v9sa1



not modelled 98.5 27 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
70d1dqna_



not modelled 98.5 16 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosyltransferases (PRTases)
71c1zuwA_



not modelled 88.3 16 PDB header:isomerase
Chain: A: PDB Molecule:glutamate racemase 1;
PDBTitle: crystal structure of b.subtilis glutamate racemase (race) with d-glu
72c2zskA_



not modelled 86.7 13 PDB header:unknown function
Chain: A: PDB Molecule:226aa long hypothetical aspartate racemase;
PDBTitle: crystal structure of ph1733, an aspartate racemase2 homologue, from pyrococcus horikoshii ot3
73c1sy7B_



not modelled 85.1 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:catalase 1;
PDBTitle: crystal structure of the catalase-1 from neurospora crassa, native2 structure at 1.75a resolution.
74c2eggA_



not modelled 83.9 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:shikimate 5-dehydrogenase;
PDBTitle: crystal structure of shikimate 5-dehydrogenase (aroe) from2 geobacillus kaustophilus
75c2hk8B_



not modelled 82.5 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:shikimate dehydrogenase;
PDBTitle: crystal structure of shikimate dehydrogenase from aquifex2 aeolicus at 2.35 angstrom resolution
76c2xecD_



not modelled 82.0 19 PDB header:isomerase
Chain: D: PDB Molecule:putative maleate isomerase;
PDBTitle: nocardia farcinica maleate cis-trans isomerase bound to2 tris
77c3tfxB_



not modelled 80.6 16 PDB header:lyase
Chain: B: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: crystal structure of orotidine 5'-phosphate decarboxylase from2 lactobacillus acidophilus
78c2dx7B_



not modelled 79.9 19 PDB header:isomerase
Chain: B: PDB Molecule:aspartate racemase;
PDBTitle: crystal structure of pyrococcus horikoshii ot3 aspartate racemase2 complex with citric acid
79c2jfnA_



not modelled 78.2 10 PDB header:isomerase
Chain: A: PDB Molecule:glutamate racemase;
PDBTitle: crystal structure of escherichia coli glutamate racemase2 in complex with l-glutamate and activator udp-murnac-ala
80c3fbtB_



not modelled 77.3 14 PDB header:oxidoreductase, lyase
Chain: B: PDB Molecule:chorismate mutase and shikimate 5-dehydrogenase
PDBTitle: crystal structure of a chorismate mutase/shikimate 5-2 dehydrogenase fusion protein from clostridium3 acetobutylicum
81c3hfrA_



not modelled 77.2 14 PDB header:isomerase
Chain: A: PDB Molecule:glutamate racemase;
PDBTitle: crystal structure of glutamate racemase from listeria monocytogenes
82d1gtea3



not modelled 77.0 20 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:C-terminal domain of adrenodoxin reductase-like
83c1vi2B_



not modelled 76.6 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:shikimate 5-dehydrogenase 2;
PDBTitle: crystal structure of shikimate-5-dehydrogenase with nad
84c2cnwF_



not modelled 75.6 18 PDB header:signal recognition
Chain: F: PDB Molecule:cell division protein ftsy;
PDBTitle: gdpalf4 complex of the srp gtpases ffh and ftsy
85c3r2uC_



not modelled 72.7 26 PDB header:hydrolase
Chain: C: PDB Molecule:metallo-beta-lactamase family protein;
PDBTitle: 2.1 angstrom resolution crystal structure of metallo-beta-lactamase2 from staphylococcus aureus subsp. aureus col
86c2px0D_



not modelled 72.4 11 PDB header:biosynthetic protein
Chain: D: PDB Molecule:flagellar biosynthesis protein flhf;
PDBTitle: crystal structure of flhf complexed with gmppnp/mg(2+)
87c3donA_



not modelled 71.2 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:shikimate dehydrogenase;
PDBTitle: crystal structure of shikimate dehydrogenase from staphylococcus2 epidermidis
88c3tozA_



not modelled 71.1 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:shikimate dehydrogenase;
PDBTitle: 2.2 angstrom crystal structure of shikimate 5-dehydrogenase from2 listeria monocytogenes in complex with nad.
89d1vi2a1



not modelled 70.3 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
90d1vmka_



not modelled 68.5 12 Fold:Phosphorylase/hydrolase-like
Superfamily:Purine and uridine phosphorylases
Family:Purine and uridine phosphorylases
91c3sg0A_



not modelled 68.4 12 PDB header:signaling protein
Chain: A: PDB Molecule:extracellular ligand-binding receptor;
PDBTitle: the crystal structure of an extracellular ligand-binding receptor from2 rhodopseudomonas palustris haa2
92d1efpb_



not modelled 67.0 15 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:ETFP subunits
93d1losc_



not modelled 66.4 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
94c3dmdA_



not modelled 66.4 13 PDB header:transport protein
Chain: A: PDB Molecule:signal recognition particle receptor;
PDBTitle: structures and conformations in solution of the signal recognition2 particle receptor from the archaeon pyrococcus furiosus
95c3o8qB_



not modelled 65.9 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:shikimate 5-dehydrogenase i alpha;
PDBTitle: 1.45 angstrom resolution crystal structure of shikimate 5-2 dehydrogenase (aroe) from vibrio cholerae
96c3hp7A_



not modelled 65.0 31 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hemolysin, putative;
PDBTitle: putative hemolysin from streptococcus thermophilus.
97c2gzmB_



not modelled 64.9 16 PDB header:isomerase
Chain: B: PDB Molecule:glutamate racemase;
PDBTitle: crystal structure of the glutamate racemase from bacillus2 anthracis
98d1vp8a_



not modelled 63.3 25 Fold:Pyruvate kinase C-terminal domain-like
Superfamily:PK C-terminal domain-like
Family:MTH1675-like
99c2dgdD_



not modelled 63.2 8 PDB header:lyase
Chain: D: PDB Molecule:223aa long hypothetical arylmalonate decarboxylase;
PDBTitle: crystal structure of st0656, a function unknown protein from2 sulfolobus tokodaii
100c3uagA_



not modelled 63.2 13 PDB header:ligase
Chain: A: PDB Molecule:protein (udp-n-acetylmuramoyl-l-alanine:d-
PDBTitle: udp-n-acetylmuramoyl-l-alanine:d-glutamate ligase
101d1p77a1



not modelled 63.1 9 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
102c3dm5A_



not modelled 62.1 13 PDB header:rna binding protein, transport protein
Chain: A: PDB Molecule:signal recognition 54 kda protein;
PDBTitle: structures of srp54 and srp19, the two proteins assembling2 the ribonucleic core of the signal recognition particle3 from the archaeon pyrococcus furiosus.
103c3euaD_



not modelled 61.7 14 PDB header:isomerase
Chain: D: PDB Molecule:putative fructose-aminoacid-6-phosphate deglycase;
PDBTitle: crystal structure of a putative phosphosugar isomerase (bsu32610) from2 bacillus subtilis at 1.90 a resolution
104c2a3nA_



not modelled 60.6 15 PDB header:sugar binding protein
Chain: A: PDB Molecule:putative glucosamine-fructose-6-phosphate aminotransferase;
PDBTitle: crystal structure of a putative glucosamine-fructose-6-phosphate2 aminotransferase (stm4540.s) from salmonella typhimurium lt2 at 1.353 a resolution
105c3dfzB_



not modelled 60.3 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:precorrin-2 dehydrogenase;
PDBTitle: sirc, precorrin-2 dehydrogenase
106d1j8yf2



not modelled 60.1 10 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nitrogenase iron protein-like
107d1eixa_



not modelled 59.8 17 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
108c2xf4A_



not modelled 59.6 32 PDB header:hydrolase
Chain: A: PDB Molecule:hydroxyacylglutathione hydrolase;
PDBTitle: crystal structure of salmonella enterica serovar2 typhimurium ycbl
109c3navB_



not modelled 59.6 15 PDB header:lyase
Chain: B: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: crystal structure of an alpha subunit of tryptophan synthase from2 vibrio cholerae o1 biovar el tor str. n16961
110d1cjca1



not modelled 59.2 32 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:C-terminal domain of adrenodoxin reductase-like
111c3lubE_



not modelled 58.4 21 PDB header:hydrolase
Chain: E: PDB Molecule:putative creatinine amidohydrolase;
PDBTitle: crystal structure of putative creatinine amidohydrolase2 (yp_211512.1) from bacteroides fragilis nctc 9343 at 2.11 a3 resolution
112c3la8A_



not modelled 58.2 16 PDB header:transferase
Chain: A: PDB Molecule:putative purine nucleoside phosphorylase;
PDBTitle: the crystal structure of smu.1229 from streptococcus mutans ua159
113d1km4a_



not modelled 57.6 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
114c3pwzA_



not modelled 57.3 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:shikimate dehydrogenase 3;
PDBTitle: crystal structure of an ael1 enzyme from pseudomonas putida
115c3ek2D_



not modelled 57.0 24 PDB header:oxidoreductase
Chain: D: PDB Molecule:enoyl-(acyl-carrier-protein) reductase (nadh);
PDBTitle: crystal structure of eonyl-(acyl carrier protein) reductase2 from burkholderia pseudomallei 1719b
116c2j7pA_



not modelled 56.9 11 PDB header:signal recognition
Chain: A: PDB Molecule:signal recognition particle protein;
PDBTitle: gmppnp-stabilized ng domain complex of the srp gtpases ffh2 and ftsy
117c3shoA_



not modelled 56.2 16 PDB header:transcription regulator
Chain: A: PDB Molecule:transcriptional regulator, rpir family;
PDBTitle: crystal structure of rpir transcription factor from sphaerobacter2 thermophilus (sugar isomerase domain)
118c3b9qA_



not modelled 55.5 17 PDB header:protein transport
Chain: A: PDB Molecule:chloroplast srp receptor homolog, alpha subunit
PDBTitle: the crystal structure of cpftsy from arabidopsis thaliana
119d1qsga_



not modelled 55.4 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
120c3qw3B_



not modelled 55.4 16 PDB header:transferase, lyase
Chain: B: PDB Molecule:orotidine-5-phosphate decarboxylase/orotate
PDBTitle: structure of leishmania donovani omp decarboxylase

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0