Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	D	Y	R	K	I	I	K	E	I	G	R	G	K	N	H	A	R	D	L	D	R	D	T	A	R	G	L	Y	A	H	M	L	N	G	E	V	P	D	L	E	L	G	G	V	L	I	A	L	R	I	K	G	E	G	E	A	E	M	L
Secondary structure
SS confidence
Disorder		?	?												?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	F	Y	E	A	M	Q	N	H	T	I	K	L	T	P	P	A	G	K	P	M	P	I	V	I	P	S	Y	N	G	A	R	K	Q	A	N	L	T	P	L	L	A	I	L	L	H	K	L	G	F	P	V	V	V	H	G	V	S	E	D
Secondary structure
SS confidence
Disorder																	?																																										?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		P	T	R	V	L	T	E	T	I	F	E	L	M	G	I	T	P	T	L	H	G	G	Q	A	Q	A	K	L	D	E	H	Q	P	V	F	M	P	V	G	A	F	C	P	P	L	E	K	Q	L	A	M	R	W	R	M	G	V	R	N	S
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	H	T	L	A	K	L	A	T	P	F	A	E	G	E	A	L	R	L	S	S	V	S	H	P	E	Y	I	G	R	V	A	K	F	F	S	D	I	G	G	R	A	L	L	M	H	G	T	E	G	E	V	Y	A	N	P	Q	R	C	P
Secondary structure
SS confidence
Disorder															?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		Q	I	N	L	I	D	R	E	G	M	R	V	L	Y	E	K	Q	D	T	A	G	S	E	L	L	P	Q	A	K	D	P	E	T	T	A	Q	W	I	E	R	C	L	A	G	S	E	P	I	P	E	S	L	K	I	Q	M	A	C	C	L
Secondary structure
SS confidence
Disorder																				?	?		?		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320
Sequence		V	A	T	G	E	A	A	T	I	S	D	G	L	A	R	V	N	Q	A	F
Secondary structure
SS confidence
Disorder																				?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1v8g chain B Region: 5 - 320 Aligned: 304 Modelled: 315 Confidence: 100.0% Identity: 22% PDB header:transferase Chain: B: PDB Molecule:anthranilate phosphoribosyltransferase; PDBTitle: crystal structure of anthranilate phosphoribosyltransferase2 (trpd) from thermus thermophilus hb8 Phyre2 PDB 1o17 chain A Region: 1 - 320 Aligned: 306 Modelled: 313 Confidence: 100.0% Identity: 24% PDB header:transferase Chain: A: PDB Molecule:anthranilate phosphoribosyltransferase; PDBTitle: anthranilate phosphoribosyl-transferase (trpd) Phyre2 PDB 1khd chain D Region: 2 - 320 Aligned: 307 Modelled: 319 Confidence: 100.0% Identity: 18% PDB header:transferase Chain: D: PDB Molecule:anthranilate phosphoribosyltransferase; PDBTitle: crystal structure analysis of the anthranilate2 phosphoribosyltransferase from erwinia carotovora at 1.93 resolution (current name, pectobacterium carotovorum) Phyre2 PDB 2bpq chain B Region: 2 - 320 Aligned: 305 Modelled: 315 Confidence: 100.0% Identity: 21% PDB header:transferase Chain: B: PDB Molecule:anthranilate phosphoribosyltransferase; PDBTitle: anthranilate phosphoribosyltransferase (trpd) from2 mycobacterium tuberculosis (apo structure) Phyre2 PDB 1vqu chain B Region: 2 - 320 Aligned: 303 Modelled: 309 Confidence: 100.0% Identity: 20% PDB header:transferase Chain: B: PDB Molecule:anthranilate phosphoribosyltransferase 2; PDBTitle: crystal structure of anthranilate phosphoribosyltransferase 22 (17130499) from nostoc sp. at 1.85 a resolution Phyre2 PDB 3h5q chain A Region: 5 - 320 Aligned: 289 Modelled: 291 Confidence: 100.0% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:pyrimidine-nucleoside phosphorylase; PDBTitle: crystal structure of a putative pyrimidine-nucleoside phosphorylase2 from staphylococcus aureus Phyre2 PDB 1brw chain B Region: 1 - 320 Aligned: 292 Modelled: 301 Confidence: 100.0% Identity: 16% PDB header:transferase Chain: B: PDB Molecule:protein (pyrimidine nucleoside phosphorylase); PDBTitle: the crystal structure of pyrimidine nucleoside2 phosphorylase in a closed conformation Phyre2 PDB 1o17 chain A domain 2 Region: 80 - 320 Aligned: 236 Modelled: 241 Confidence: 100.0% Identity: 19% Fold: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Superfamily: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Family: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Phyre2 PDB 2elc chain A domain 2 Region: 73 - 320 Aligned: 240 Modelled: 246 Confidence: 100.0% Identity: 21% Fold: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Superfamily: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Family: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Phyre2 PDB 2j0f chain C Region: 2 - 320 Aligned: 292 Modelled: 302 Confidence: 100.0% Identity: 18% PDB header:transferase Chain: C: PDB Molecule:thymidine phosphorylase; PDBTitle: structural basis for non-competitive product inhibition in2 human thymidine phosphorylase: implication for drug design Phyre2 PDB 2dsj chain A Region: 1 - 320 Aligned: 287 Modelled: 302 Confidence: 100.0% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:pyrimidine-nucleoside (thymidine) phosphorylase; PDBTitle: crystal structure of project id tt0128 from thermus thermophilus hb8 Phyre2 PDB 1otp chain A Region: 1 - 320 Aligned: 284 Modelled: 291 Confidence: 100.0% Identity: 13% PDB header:phosphorylase Chain: A: PDB Molecule:thymidine phosphorylase; PDBTitle: structural and theoretical studies suggest domain movement produces an2 active conformation of thymidine phosphorylase Phyre2 PDB 1khd chain A domain 2 Region: 76 - 320 Aligned: 232 Modelled: 245 Confidence: 100.0% Identity: 18% Fold: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Superfamily: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Family: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Phyre2 PDB 1uou chain A domain 2 Region: 72 - 320 Aligned: 225 Modelled: 245 Confidence: 100.0% Identity: 16% Fold: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Superfamily: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Family: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Phyre2 PDB 1brw chain A domain 2 Region: 77 - 320 Aligned: 222 Modelled: 235 Confidence: 100.0% Identity: 12% Fold: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Superfamily: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Family: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Phyre2 PDB 2tpt chain A domain 2 Region: 77 - 320 Aligned: 220 Modelled: 225 Confidence: 100.0% Identity: 13% Fold: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Superfamily: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Family: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Phyre2 PDB 1o17 chain A domain 1 Region: 1 - 74 Aligned: 70 Modelled: 74 Confidence: 99.7% Identity: 37% Fold: Methionine synthase domain-like Superfamily: Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Family: Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Phyre2 PDB 1khd chain A domain 1 Region: 2 - 74 Aligned: 69 Modelled: 73 Confidence: 99.6% Identity: 20% Fold: Methionine synthase domain-like Superfamily: Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Family: Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Phyre2 PDB 1brw chain A domain 1 Region: 1 - 74 Aligned: 70 Modelled: 74 Confidence: 99.6% Identity: 21% Fold: Methionine synthase domain-like Superfamily: Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Family: Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Phyre2 PDB 2tpt chain A domain 1 Region: 1 - 73 Aligned: 69 Modelled: 73 Confidence: 99.6% Identity: 13% Fold: Methionine synthase domain-like Superfamily: Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Family: Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Phyre2 1 c1v8gB_ 2 c1o17A_ 3 c1khdD_ 4 c2bpqB_ 5 c1vquB_ 6 c3h5qA_ 7 c1brwB_ 8 d1o17a2 9 d2elca2 10 c2j0fC_ 11 c2dsjA_ 12 c1otpA_ 13 d1khda2 14 d1uoua2 15 d1brwa2 16 d2tpta2 17 d1o17a1 18 d1khda1 19 d1brwa1 20 d2tpta1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1v8gB_ 100.0 22 PDB header:transferase Chain: B: PDB Molecule:anthranilate phosphoribosyltransferase; PDBTitle: crystal structure of anthranilate phosphoribosyltransferase2 (trpd) from thermus thermophilus hb8 2 c1o17A_ 100.0 24 PDB header:transferase Chain: A: PDB Molecule:anthranilate phosphoribosyltransferase; PDBTitle: anthranilate phosphoribosyl-transferase (trpd) 3 c1khdD_ 100.0 18 PDB header:transferase Chain: D: PDB Molecule:anthranilate phosphoribosyltransferase; PDBTitle: crystal structure analysis of the anthranilate2 phosphoribosyltransferase from erwinia carotovora at 1.93 resolution (current name, pectobacterium carotovorum) 4 c2bpqB_ 100.0 21 PDB header:transferase Chain: B: PDB Molecule:anthranilate phosphoribosyltransferase; PDBTitle: anthranilate phosphoribosyltransferase (trpd) from2 mycobacterium tuberculosis (apo structure) 5 c1vquB_ 100.0 20 PDB header:transferase Chain: B: PDB Molecule:anthranilate phosphoribosyltransferase 2; PDBTitle: crystal structure of anthranilate phosphoribosyltransferase 22 (17130499) from nostoc sp. at 1.85 a resolution 6 c3h5qA_ 100.0 18 PDB header:transferase Chain: A: PDB Molecule:pyrimidine-nucleoside phosphorylase; PDBTitle: crystal structure of a putative pyrimidine-nucleoside phosphorylase2 from staphylococcus aureus 7 c1brwB_ 100.0 16 PDB header:transferase Chain: B: PDB Molecule:protein (pyrimidine nucleoside phosphorylase); PDBTitle: the crystal structure of pyrimidine nucleoside2 phosphorylase in a closed conformation 8 d1o17a2 100.0 19 Fold:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Superfamily:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Family:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 9 d2elca2 100.0 21 Fold:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Superfamily:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Family:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 10 c2j0fC_ 100.0 18 PDB header:transferase Chain: C: PDB Molecule:thymidine phosphorylase; PDBTitle: structural basis for non-competitive product inhibition in2 human thymidine phosphorylase: implication for drug design 11 c2dsjA_ 100.0 17 PDB header:transferase Chain: A: PDB Molecule:pyrimidine-nucleoside (thymidine) phosphorylase; PDBTitle: crystal structure of project id tt0128 from thermus thermophilus hb8 12 c1otpA_ 100.0 13 PDB header:phosphorylase Chain: A: PDB Molecule:thymidine phosphorylase; PDBTitle: structural and theoretical studies suggest domain movement produces an2 active conformation of thymidine phosphorylase 13 d1khda2 100.0 18 Fold:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Superfamily:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Family:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 14 d1uoua2 100.0 16 Fold:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Superfamily:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Family:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 15 d1brwa2 100.0 12 Fold:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Superfamily:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Family:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 16 d2tpta2 100.0 13 Fold:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Superfamily:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Family:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 17 d1o17a1 99.7 37 Fold:Methionine synthase domain-like Superfamily:Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Family:Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain 18 d1khda1 99.6 20 Fold:Methionine synthase domain-like Superfamily:Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Family:Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain 19 d1brwa1 99.6 21 Fold:Methionine synthase domain-like Superfamily:Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Family:Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain 20 d2tpta1 99.6 13 Fold:Methionine synthase domain-like Superfamily:Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Family:Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain 21 d1v8ga1 not modelled 99.5 25 Fold:Methionine synthase domain-like Superfamily:Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Family:Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain 22 d1uoua1 not modelled 99.5 23 Fold:Methionine synthase domain-like Superfamily:Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Family:Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain 23 d2elca1 not modelled 99.1 27 Fold:Methionine synthase domain-like Superfamily:Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Family:Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain 24 d1vkma_ not modelled 90.5 18 Fold:Indigoidine synthase A-like Superfamily:Indigoidine synthase A-like Family:Indigoidine synthase A-like 25 d1tuea_ not modelled 72.9 16 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 26 d1svma_ not modelled 71.7 16 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 27 d1kfia1 not modelled 69.0 12 Fold:Phosphoglucomutase, first 3 domains Superfamily:Phosphoglucomutase, first 3 domains Family:Phosphoglucomutase, first 3 domains 28 c2kvcA_ not modelled 68.6 13 PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: solution structure of the mycobacterium tuberculosis protein rv0543c,2 a member of the duf3349 superfamily. seattle structural genomics3 center for infectious disease target mytud.17112.a 29 d1p88a_ not modelled 68.5 17 Fold:IF3-like Superfamily:EPT/RTPC-like Family:Enolpyruvate transferase, EPT 30 c2o0zA_ not modelled 66.9 14 PDB header:transferase Chain: A: PDB Molecule:3-phosphoshikimate 1-carboxyvinyltransferase; PDBTitle: mycobacterium tuberculosis epsp synthase in complex with2 product (eps) 31 d2gc6a2 not modelled 64.6 12 Fold:Ribokinase-like Superfamily:MurD-like peptide ligases, catalytic domain Family:Folylpolyglutamate synthetase 32 c2lkyA_ not modelled 61.3 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution structure of msmeg_1053, the second duf3349 annotated protein2 in the genome of mycobacterium smegmatis, seattle structural genomics3 center for infectious disease target mysma.17112.b 33 c2px0D_ not modelled 60.6 14 PDB header:biosynthetic protein Chain: D: PDB Molecule:flagellar biosynthesis protein flhf; PDBTitle: crystal structure of flhf complexed with gmppnp/mg(2+) 34 c3n2aA_ not modelled 51.2 18 PDB header:ligase Chain: A: PDB Molecule:bifunctional folylpolyglutamate synthase/dihydrofolate PDBTitle: crystal structure of bifunctional folylpolyglutamate2 synthase/dihydrofolate synthase from yersinia pestis co92 35 c2yvqA_ not modelled 50.8 13 PDB header:ligase Chain: A: PDB Molecule:carbamoyl-phosphate synthase; PDBTitle: crystal structure of mgs domain of carbamoyl-phosphate2 synthetase from homo sapiens 36 c3chgB_ not modelled 47.8 21 PDB header:ligand binding protein Chain: B: PDB Molecule:glycine betaine-binding protein; PDBTitle: the compatible solute-binding protein opuac from bacillus2 subtilis in complex with dmsa 37 c2gc6A_ not modelled 47.2 18 PDB header:ligase Chain: A: PDB Molecule:folylpolyglutamate synthase; PDBTitle: s73a mutant of l. casei fpgs 38 c1kfiA_ not modelled 46.8 12 PDB header:isomerase Chain: A: PDB Molecule:phosphoglucomutase 1; PDBTitle: crystal structure of the exocytosis-sensitive2 phosphoprotein, pp63/parafusin (phosphoglucomutase) from3 paramecium 39 d3pmga1 not modelled 46.7 10 Fold:Phosphoglucomutase, first 3 domains Superfamily:Phosphoglucomutase, first 3 domains Family:Phosphoglucomutase, first 3 domains 40 d1j9ia_ not modelled 45.6 11 Fold:Putative DNA-binding domain Superfamily:Putative DNA-binding domain Family:Terminase gpNU1 subunit domain 41 c2cnwF_ not modelled 45.2 17 PDB header:signal recognition Chain: F: PDB Molecule:cell division protein ftsy; PDBTitle: gdpalf4 complex of the srp gtpases ffh and ftsy 42 d1rf6a_ not modelled 44.9 16 Fold:IF3-like Superfamily:EPT/RTPC-like Family:Enolpyruvate transferase, EPT 43 c1w96B_ not modelled 43.1 8 PDB header:ligase Chain: B: PDB Molecule:acetyl-coenzyme a carboxylase; PDBTitle: crystal structure of biotin carboxylase domain of acetyl-2 coenzyme a carboxylase from saccharomyces cerevisiae in3 complex with soraphen a 44 c3k2gA_ not modelled 42.2 11 PDB header:resiniferatoxin binding protein Chain: A: PDB Molecule:resiniferatoxin-binding, phosphotriesterase- PDBTitle: crystal structure of a resiniferatoxin-binding protein from2 rhodobacter sphaeroides 45 c1r71B_ not modelled 41.5 13 PDB header:transcription/dna Chain: B: PDB Molecule:transcriptional repressor protein korb; PDBTitle: crystal structure of the dna binding domain of korb in2 complex with the operator dna 46 d2jwda1 not modelled 39.6 11 Fold:immunoglobulin/albumin-binding domain-like Superfamily:Bacterial immunoglobulin/albumin-binding domains Family:Immunoglobulin-binding protein A modules 47 c2pqdA_ not modelled 39.5 16 PDB header:transferase Chain: A: PDB Molecule:3-phosphoshikimate 1-carboxyvinyltransferase; PDBTitle: a100g cp4 epsps liganded with (r)-difluoromethyl tetrahedral reaction2 intermediate analog 48 d1ukza_ not modelled 38.9 14 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 49 c3rmtB_ not modelled 37.8 17 PDB header:transferase Chain: B: PDB Molecule:3-phosphoshikimate 1-carboxyvinyltransferase 1; PDBTitle: crystal structure of putative 5-enolpyruvoylshikimate-3-phosphate2 synthase from bacillus halodurans c-125 50 d1ejda_ not modelled 37.5 11 Fold:IF3-like Superfamily:EPT/RTPC-like Family:Enolpyruvate transferase, EPT 51 d1tz9a_ not modelled 36.9 12 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:UxuA-like 52 d1r71a_ not modelled 36.7 14 Fold:DNA/RNA-binding 3-helical bundle Superfamily:KorB DNA-binding domain-like Family:KorB DNA-binding domain-like 53 c2qguA_ not modelled 36.2 2 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:probable signal peptide protein; PDBTitle: three-dimensional structure of the phospholipid-binding protein from2 ralstonia solanacearum q8xv73_ralsq in complex with a phospholipid at3 the resolution 1.53 a. northeast structural genomics consortium4 target rsr89 54 c3r38A_ not modelled 35.8 13 PDB header:transferase Chain: A: PDB Molecule:udp-n-acetylglucosamine 1-carboxyvinyltransferase 1; PDBTitle: 2.23 angstrom resolution crystal structure of udp-n-acetylglucosamine2 1-carboxyvinyltransferase (mura) from listeria monocytogenes egd-e 55 c2oz5A_ not modelled 35.0 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:phosphotyrosine protein phosphatase ptpb; PDBTitle: crystal structure of mycobacterium tuberculosis protein tyrosine2 phosphatase ptpb in complex with the specific inhibitor omts 56 c3jvpA_ not modelled 34.7 12 PDB header:transferase Chain: A: PDB Molecule:ribulokinase; PDBTitle: crystal structure of ribulokinase from bacillus halodurans 57 c1w78A_ not modelled 34.4 18 PDB header:synthase Chain: A: PDB Molecule:folc bifunctional protein; PDBTitle: e.coli folc in complex with dhpp and adp 58 c3ewbX_ not modelled 34.4 9 PDB header:transferase Chain: X: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of n-terminal domain of putative 2-2 isopropylmalate synthase from listeria monocytogenes 59 c3eegB_ not modelled 34.2 8 PDB header:transferase Chain: B: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of a 2-isopropylmalate synthase from2 cytophaga hutchinsonii 60 c3bg3B_ not modelled 34.1 10 PDB header:ligase Chain: B: PDB Molecule:pyruvate carboxylase, mitochondrial; PDBTitle: crystal structure of human pyruvate carboxylase (missing2 the biotin carboxylase domain at the n-terminus) 61 c1nsfA_ not modelled 33.9 17 PDB header:protein transport Chain: A: PDB Molecule:n-ethylmaleimide sensitive factor; PDBTitle: d2 hexamerization domain of n-ethylmaleimide sensitive factor (nsf) 62 d1a0pa2 not modelled 32.8 23 Fold:DNA breaking-rejoining enzymes Superfamily:DNA breaking-rejoining enzymes Family:Lambda integrase-like, catalytic core 63 d1uaea_ not modelled 32.3 10 Fold:IF3-like Superfamily:EPT/RTPC-like Family:Enolpyruvate transferase, EPT 64 c1rr2A_ not modelled 30.8 20 PDB header:transferase Chain: A: PDB Molecule:transcarboxylase 5s subunit; PDBTitle: propionibacterium shermanii transcarboxylase 5s subunit bound to 2-2 ketobutyric acid 65 c2yhsA_ not modelled 30.7 18 PDB header:cell cycle Chain: A: PDB Molecule:cell division protein ftsy; PDBTitle: structure of the e. coli srp receptor ftsy 66 d1g6sa_ not modelled 30.6 18 Fold:IF3-like Superfamily:EPT/RTPC-like Family:Enolpyruvate transferase, EPT 67 d1ywfa1 not modelled 29.9 15 Fold:(Phosphotyrosine protein) phosphatases II Superfamily:(Phosphotyrosine protein) phosphatases II Family:Mycobacterial PtpB-like 68 c2ip4A_ not modelled 29.5 16 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylamine--glycine ligase; PDBTitle: crystal structure of glycinamide ribonucleotide synthetase from2 thermus thermophilus hb8 69 c3dnfB_ not modelled 29.3 10 PDB header:oxidoreductase Chain: B: PDB Molecule:4-hydroxy-3-methylbut-2-enyl diphosphate reductase; PDBTitle: structure of (e)-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase,2 the terminal enzyme of the non-mevalonate pathway 70 c2vosA_ not modelled 28.6 14 PDB header:ligase Chain: A: PDB Molecule:folylpolyglutamate synthase protein folc; PDBTitle: mycobacterium tuberculosis folylpolyglutamate synthase2 complexed with adp 71 c2iy3A_ not modelled 27.6 15 PDB header:rna-binding Chain: A: PDB Molecule:signal recognition particle protein ffh; PDBTitle: structure of the e. coli signal recognition particle2 bound to a translating ribosome 72 d1b8za_ not modelled 26.9 10 Fold:IHF-like DNA-binding proteins Superfamily:IHF-like DNA-binding proteins Family:Prokaryotic DNA-bending protein 73 d1wb9a2 not modelled 26.6 20 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:ABC transporter ATPase domain-like 74 c3ol4B_ not modelled 26.5 14 PDB header:unknown function Chain: B: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of a putative uncharacterized protein from2 mycobacterium smegmatis, an ortholog of rv0543c 75 c2j37W_ not modelled 26.4 13 PDB header:ribosome Chain: W: PDB Molecule:signal recognition particle 54 kda protein PDBTitle: model of mammalian srp bound to 80s rncs 76 d1o5za2 not modelled 25.9 21 Fold:Ribokinase-like Superfamily:MurD-like peptide ligases, catalytic domain Family:Folylpolyglutamate synthetase 77 c3bdkB_ not modelled 25.6 10 PDB header:lyase Chain: B: PDB Molecule:d-mannonate dehydratase; PDBTitle: crystal structure of streptococcus suis mannonate2 dehydratase complexed with substrate analogue 78 c3kc2A_ not modelled 25.4 11 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized protein ykr070w; PDBTitle: crystal structure of mitochondrial had-like phosphatase from2 saccharomyces cerevisiae 79 c2dmxA_ not modelled 25.0 8 PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily b member 8; PDBTitle: solution structure of the j domain of dnaj homolog2 subfamily b member 8 80 d2jdid1 not modelled 24.9 12 Fold:Left-handed superhelix Superfamily:C-terminal domain of alpha and beta subunits of F1 ATP synthase Family:C-terminal domain of alpha and beta subunits of F1 ATP synthase 81 d1ak2a1 not modelled 24.2 20 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 82 d1ewqa2 not modelled 24.1 12 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:ABC transporter ATPase domain-like 83 c2hjwA_ not modelled 24.1 15 PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: crystal structure of the bc domain of acc2 84 d2afhe1 not modelled 23.5 21 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nitrogenase iron protein-like 85 d1fc2c_ not modelled 23.5 14 Fold:immunoglobulin/albumin-binding domain-like Superfamily:Bacterial immunoglobulin/albumin-binding domains Family:Immunoglobulin-binding protein A modules 86 c3eihB_ not modelled 23.3 14 PDB header:protein transport Chain: B: PDB Molecule:vacuolar protein sorting-associated protein 4; PDBTitle: crystal structure of s.cerevisiae vps4 in the presence of atpgammas 87 c3ff5B_ not modelled 23.0 15 PDB header:protein transport Chain: B: PDB Molecule:peroxisomal biogenesis factor 14; PDBTitle: crystal structure of the conserved n-terminal domain of the2 peroxisomal matrix-protein-import receptor, pex14p 88 c1wbdA_ not modelled 22.9 20 PDB header:dna-binding Chain: A: PDB Molecule:dna mismatch repair protein muts; PDBTitle: crystal structure of e. coli dna mismatch repair enzyme2 muts, e38q mutant, in complex with a g.t mismatch 89 d1mula_ not modelled 22.8 20 Fold:IHF-like DNA-binding proteins Superfamily:IHF-like DNA-binding proteins Family:Prokaryotic DNA-bending protein 90 d1sr9a2 not modelled 22.6 9 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:HMGL-like 91 c2dn9A_ not modelled 22.6 5 PDB header:apoptosis, chaperone Chain: A: PDB Molecule:dnaj homolog subfamily a member 3; PDBTitle: solution structure of j-domain from the dnaj homolog, human2 tid1 protein 92 d1g5ta_ not modelled 22.2 19 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:RecA protein-like (ATPase-domain) 93 c2w40C_ not modelled 22.0 10 PDB header:transferase Chain: C: PDB Molecule:glycerol kinase, putative; PDBTitle: crystal structure of plasmodium falciparum glycerol kinase2 with bound glycerol 94 c3roiA_ not modelled 21.9 22 PDB header:transferase Chain: A: PDB Molecule:3-phosphoshikimate 1-carboxyvinyltransferase; PDBTitle: 2.20 angstrom resolution structure of 3-phosphoshikimate 1-2 carboxyvinyltransferase (aroa) from coxiella burnetii 95 c2iz1C_ not modelled 21.9 15 PDB header:oxidoreductase Chain: C: PDB Molecule:6-phosphogluconate dehydrogenase, decarboxylating; PDBTitle: 6pdh complexed with pex inhibitor synchrotron data 96 d1tlha_ not modelled 21.8 28 Fold:Anti-sigma factor AsiA Superfamily:Anti-sigma factor AsiA Family:Anti-sigma factor AsiA 97 c3endA_ not modelled 21.7 18 PDB header:oxidoreductase Chain: A: PDB Molecule:light-independent protochlorophyllide reductase PDBTitle: crystal structure of the l protein of rhodobacter2 sphaeroides light-independent protochlorophyllide3 reductase (bchl) with mgadp bound: a homologue of the4 nitrogenase fe protein 98 d1rqba2 not modelled 21.2 15 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:HMGL-like 99 d1g64b_ not modelled 21.1 19 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:RecA protein-like (ATPase-domain) 100 d1iura_ not modelled 21.1 9 Fold:Long alpha-hairpin Superfamily:Chaperone J-domain Family:Chaperone J-domain 101 c2yztA_ not modelled 21.0 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative uncharacterized protein ttha1756; PDBTitle: crystal structure of uncharacterized conserved protein from thermus2 thermophilus hb8 102 c1djyB_ not modelled 20.9 15 PDB header:lipid degradation Chain: B: PDB Molecule:phosphoinositide-specific phospholipase c, PDBTitle: phosphoinositide-specific phospholipase c-delta1 from rat2 complexed with inositol-2,4,5-trisphosphate 103 d1gvnb_ not modelled 20.5 11 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Plasmid maintenance system epsilon/zeta, toxin zeta subunit 104 c1o5zA_ not modelled 20.3 21 PDB header:ligase Chain: A: PDB Molecule:folylpolyglutamate synthase/dihydrofolate synthase; PDBTitle: crystal structure of folylpolyglutamate synthase (tm0166) from2 thermotoga maritima at 2.10 a resolution

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0