Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP37759
DateThu Jan 5 11:57:31 GMT 2012
Unique Job IDd45653c4d203d00e

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1kewa_
Top template information
Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
Confidence and coverage
Confidence:100.0% Coverage:100%
361 residues (100% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MKILVTGGAGFIGSAVVRHIINNTQDSVVNVDKLTYAGNRESLADVSDSERYVFEHADIC
Secondary structure 
SS confidence 
Disorder  ?
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  DAPAMARIFAQHQPDAVMHLAAESHVDRSITGPAAFIETNIVGTYVLLEAARNYWSALDS
Secondary structure 
SS confidence 
Disorder 
????
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  DKKNSFRFHHISTDEVYGDLPHPDEVNNTEELPLFTETTAYAPSSPYSASKASSDHLVRA
Secondary structure 
SS confidence 
Disorder  ?
??????
??
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  WKRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEGKALPIYGKGDQIRDWLYVEDHA
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  RALYTVVTEGKAGETYNIGGHNEKKNIDVVLTICDLLDEIVPKEKSYREQITYVADRPGH
Secondary structure 
SS confidence 
Disorder 
??
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  DRRYAIDAEKIGRALGWKPQETFESGIRKTVEWYLSNTKWVDNVKSGAYQSWIEQNYEGR
Secondary structure 
SS confidence 
Disorder 
?
??
????
Disorder confidence 
 
   .
Sequence  Q
Secondary structure 
SS confidence 
Disorder  ?
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1kew chain A

3D model

Region: 1 - 361
Aligned: 361
Modelled: 361
Confidence: 100.0%
Identity: 88%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1z45 chain A

3D model

Region: 2 - 342
Aligned: 309
Modelled: 324
Confidence: 100.0%
Identity: 25%
PDB header:isomerase
Chain: A: PDB Molecule:gal10 bifunctional protein;
PDBTitle: crystal structure of the gal10 fusion protein galactose2 mutarotase/udp-galactose 4-epimerase from saccharomyces3 cerevisiae complexed with nad, udp-glucose, and galactose

Phyre2

PDB 1bxk chain A

3D model

Region: 1 - 350
Aligned: 337
Modelled: 350
Confidence: 100.0%
Identity: 73%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1z7e chain C

3D model

Region: 1 - 337
Aligned: 317
Modelled: 327
Confidence: 100.0%
Identity: 20%
PDB header:hydrolase
Chain: C: PDB Molecule:protein arna;
PDBTitle: crystal structure of full length arna

Phyre2

PDB 1oc2 chain A

3D model

Region: 1 - 354
Aligned: 335
Modelled: 342
Confidence: 100.0%
Identity: 37%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1i24 chain A

3D model

Region: 2 - 346
Aligned: 333
Modelled: 345
Confidence: 100.0%
Identity: 18%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1r6d chain A

3D model

Region: 1 - 345
Aligned: 317
Modelled: 336
Confidence: 100.0%
Identity: 48%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 2hun chain B

3D model

Region: 1 - 344
Aligned: 317
Modelled: 344
Confidence: 100.0%
Identity: 44%
PDB header:lyase
Chain: B: PDB Molecule:336aa long hypothetical dtdp-glucose 4,6-dehydratase;
PDBTitle: crystal structure of hypothetical protein ph0414 from pyrococcus2 horikoshii ot3

Phyre2

PDB 2c5a chain A domain 1

3D model

Region: 1 - 340
Aligned: 310
Modelled: 323
Confidence: 100.0%
Identity: 16%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 2pk3 chain B

3D model

Region: 1 - 336
Aligned: 303
Modelled: 336
Confidence: 100.0%
Identity: 25%
PDB header:oxidoreductase
Chain: B: PDB Molecule:gdp-6-deoxy-d-lyxo-4-hexulose reductase;
PDBTitle: crystal structure of a gdp-4-keto-6-deoxy-d-mannose reductase

Phyre2

PDB 1n7g chain B

3D model

Region: 2 - 340
Aligned: 319
Modelled: 339
Confidence: 100.0%
Identity: 24%
PDB header:lyase
Chain: B: PDB Molecule:gdp-d-mannose-4,6-dehydratase;
PDBTitle: crystal structure of the gdp-mannose 4,6-dehydratase2 ternary complex with nadph and gdp-rhamnose.

Phyre2

PDB 1udc chain A

3D model

Region: 1 - 343
Aligned: 326
Modelled: 343
Confidence: 100.0%
Identity: 21%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 3enk chain B

3D model

Region: 2 - 339
Aligned: 312
Modelled: 329
Confidence: 100.0%
Identity: 24%
PDB header:isomerase
Chain: B: PDB Molecule:udp-glucose 4-epimerase;
PDBTitle: 1.9a crystal structure of udp-glucose 4-epimerase from2 burkholderia pseudomallei

Phyre2

PDB 2bll chain A domain 1

3D model

Region: 1 - 342
Aligned: 317
Modelled: 331
Confidence: 100.0%
Identity: 18%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1n7h chain A

3D model

Region: 2 - 340
Aligned: 316
Modelled: 339
Confidence: 100.0%
Identity: 24%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1wvg chain A domain 1

3D model

Region: 2 - 350
Aligned: 328
Modelled: 349
Confidence: 100.0%
Identity: 19%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1rkx chain A

3D model

Region: 2 - 361
Aligned: 333
Modelled: 344
Confidence: 100.0%
Identity: 20%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1z45 chain A domain 2

3D model

Region: 2 - 342
Aligned: 311
Modelled: 324
Confidence: 100.0%
Identity: 22%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1ek6 chain A

3D model

Region: 1 - 343
Aligned: 318
Modelled: 343
Confidence: 100.0%
Identity: 23%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1orr chain A

3D model

Region: 2 - 336
Aligned: 318
Modelled: 335
Confidence: 100.0%
Identity: 28%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2
1
d1kewa_
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c1z45A_
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d1bxka_
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c1z7eC_
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d1oc2a_
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d1i24a_
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d1r6da_
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c2hunB_
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d2c5aa1
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c2pk3B_
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c1n7gB_
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d1udca_
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c3enkB_
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d2blla1
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d1n7ha_
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d1wvga1
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d1rkxa_
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d1z45a2
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d1ek6a_
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d1orra_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1kewa_
100.0 88 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
2c1z45A_
100.0 25 PDB header:isomerase
Chain: A: PDB Molecule:gal10 bifunctional protein;
PDBTitle: crystal structure of the gal10 fusion protein galactose2 mutarotase/udp-galactose 4-epimerase from saccharomyces3 cerevisiae complexed with nad, udp-glucose, and galactose
3d1bxka_
100.0 73 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
4c1z7eC_
100.0 20 PDB header:hydrolase
Chain: C: PDB Molecule:protein arna;
PDBTitle: crystal structure of full length arna
5d1oc2a_
100.0 37 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
6d1i24a_
100.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
7d1r6da_
100.0 48 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
8c2hunB_
100.0 44 PDB header:lyase
Chain: B: PDB Molecule:336aa long hypothetical dtdp-glucose 4,6-dehydratase;
PDBTitle: crystal structure of hypothetical protein ph0414 from pyrococcus2 horikoshii ot3
9d2c5aa1
100.0 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
10c2pk3B_
100.0 25 PDB header:oxidoreductase
Chain: B: PDB Molecule:gdp-6-deoxy-d-lyxo-4-hexulose reductase;
PDBTitle: crystal structure of a gdp-4-keto-6-deoxy-d-mannose reductase
11c1n7gB_
100.0 24 PDB header:lyase
Chain: B: PDB Molecule:gdp-d-mannose-4,6-dehydratase;
PDBTitle: crystal structure of the gdp-mannose 4,6-dehydratase2 ternary complex with nadph and gdp-rhamnose.
12d1udca_
100.0 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
13c3enkB_
100.0 24 PDB header:isomerase
Chain: B: PDB Molecule:udp-glucose 4-epimerase;
PDBTitle: 1.9a crystal structure of udp-glucose 4-epimerase from2 burkholderia pseudomallei
14d2blla1
100.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
15d1n7ha_
100.0 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
16d1wvga1
100.0 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
17d1rkxa_
100.0 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
18d1z45a2
100.0 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
19d1ek6a_
100.0 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
20d1orra_
100.0 28 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
21d1rpna_
not modelled 100.0 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
22c2z1mC_
not modelled 100.0 21 PDB header:lyase
Chain: C: PDB Molecule:gdp-d-mannose dehydratase;
PDBTitle: crystal structure of gdp-d-mannose dehydratase from aquifex aeolicus2 vf5
23d1t2aa_
not modelled 100.0 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
24c1t2aC_
not modelled 100.0 22 PDB header:structural genomics,lyase
Chain: C: PDB Molecule:gdp-mannose 4,6 dehydratase;
PDBTitle: crystal structure of human gdp-d-mannose 4,6-dehydratase
25c2c20D_
not modelled 100.0 27 PDB header:isomerase
Chain: D: PDB Molecule:udp-glucose 4-epimerase;
PDBTitle: crystal structure of udp-glucose 4-epimerase
26c2q1uA_
not modelled 100.0 24 PDB header:sugar binding protein
Chain: A: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase;
PDBTitle: crystal structure of the bordetella bronchiseptica enzyme wbmf in2 complex with nad+ and udp
27c2p5uC_
not modelled 100.0 30 PDB header:isomerase
Chain: C: PDB Molecule:udp-glucose 4-epimerase;
PDBTitle: crystal structure of thermus thermophilus hb8 udp-glucose 4-2 epimerase complex with nad
28c2pzlB_
not modelled 100.0 21 PDB header:sugar binding protein
Chain: B: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase;
PDBTitle: crystal structure of the bordetella bronchiseptica enzyme2 wbmg in complex with nad and udp
29d1db3a_
not modelled 100.0 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
30d1gy8a_
not modelled 100.0 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
31d2b69a1
not modelled 100.0 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
32c2b69A_
not modelled 100.0 24 PDB header:lyase
Chain: A: PDB Molecule:udp-glucuronate decarboxylase 1;
PDBTitle: crystal structure of human udp-glucoronic acid decarboxylase
33d1e6ua_
not modelled 100.0 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
34c2q1wC_
not modelled 100.0 21 PDB header:sugar binding protein
Chain: C: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase;
PDBTitle: crystal structure of the bordetella bronchiseptica enzyme wbmh in2 complex with nad+
35c3lu1C_
not modelled 100.0 28 PDB header:isomerase
Chain: C: PDB Molecule:wbgu;
PDBTitle: crystal structure analysis of wbgu: a udp-galnac 4-epimerase
36c3icpA_
not modelled 100.0 26 PDB header:isomerase
Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: crystal structure of udp-galactose 4-epimerase
37c3m2pD_
not modelled 100.0 20 PDB header:isomerase
Chain: D: PDB Molecule:udp-n-acetylglucosamine 4-epimerase;
PDBTitle: the crystal structure of udp-n-acetylglucosamine 4-epimerase2 from bacillus cereus
38d1sb8a_
not modelled 100.0 29 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
39c3eheB_
not modelled 100.0 23 PDB header:isomerase
Chain: B: PDB Molecule:udp-glucose 4-epimerase (gale-1);
PDBTitle: crystal structure of udp-glucose 4 epimerase (gale-1) from2 archaeoglobus fulgidus
40c2x4gA_
not modelled 100.0 14 PDB header:isomerase
Chain: A: PDB Molecule:nucleoside-diphosphate-sugar epimerase;
PDBTitle: crystal structure of pa4631, a nucleoside-diphosphate-sugar2 epimerase from pseudomonas aeruginosa
41c3slgB_
not modelled 100.0 20 PDB header:transferase
Chain: B: PDB Molecule:pbgp3 protein;
PDBTitle: crystal structure of pbgp3 protein from burkholderia pseudomallei
42c3a1nB_
not modelled 100.0 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:ndp-sugar epimerase;
PDBTitle: crystal structure of l-threonine dehydrogenase from2 hyperthermophilic archaeon thermoplasma volcanium
43c2hrzA_
not modelled 100.0 16 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:nucleoside-diphosphate-sugar epimerase;
PDBTitle: the crystal structure of the nucleoside-diphosphate-sugar epimerase2 from agrobacterium tumefaciens
44c2iodD_
not modelled 100.0 13 PDB header:oxidoreductase
Chain: D: PDB Molecule:dihydroflavonol 4-reductase;
PDBTitle: binding of two substrate analogue molecules to2 dihydroflavonol-4-reductase alters the functional geometry3 of the catalytic site
45c2v6gA_
not modelled 100.0 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:progesterone 5-beta-reductase;
PDBTitle: structure of progesterone 5beta-reductase from digitalis2 lanata in complex with nadp
46c2yy7B_
not modelled 100.0 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:l-threonine dehydrogenase;
PDBTitle: crystal structure of thermolabile l-threonine dehydrogenase from2 flavobacterium frigidimaris kuc-1
47c2p4hX_
not modelled 100.0 17 PDB header:plant protein
Chain: X: PDB Molecule:vestitone reductase;
PDBTitle: crystal structure of vestitone reductase from alfalfa2 (medicago sativa l.)
48d1vl0a_
not modelled 100.0 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
49d1n2sa_
not modelled 100.0 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
50c2rh8A_
not modelled 100.0 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:anthocyanidin reductase;
PDBTitle: structure of apo anthocyanidin reductase from vitis vinifera
51d1y1pa1
not modelled 100.0 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
52c2x86K_
not modelled 100.0 18 PDB header:isomerase
Chain: K: PDB Molecule:adp-l-glycero-d-manno-heptose-6-epimerase;
PDBTitle: agme bound to adp-b-mannose
53c3oh8A_
not modelled 100.0 15 PDB header:isomerase
Chain: A: PDB Molecule:nucleoside-diphosphate sugar epimerase (sula family);
PDBTitle: crystal structure of the nucleoside-diphosphate sugar epimerase from2 corynebacterium glutamicum. northeast structural genomics consortium3 target cgr91
54c3sc6F_
not modelled 100.0 17 PDB header:oxidoreductase
Chain: F: PDB Molecule:dtdp-4-dehydrorhamnose reductase;
PDBTitle: 2.65 angstrom resolution crystal structure of dtdp-4-dehydrorhamnose2 reductase (rfbd) from bacillus anthracis str. ames in complex with3 nadp
55c3gpiA_
not modelled 100.0 15 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: structure of putative nad-dependent epimerase/dehydratase2 from methylobacillus flagellatus
56d1eq2a_
not modelled 100.0 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
57c2ydyA_
not modelled 100.0 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:methionine adenosyltransferase 2 subunit beta;
PDBTitle: crystal structure of human s-adenosylmethionine synthetase2 2, beta subunit in orthorhombic crystal form
58c2ggsB_
not modelled 100.0 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:273aa long hypothetical dtdp-4-dehydrorhamnose
PDBTitle: crystal structure of hypothetical dtdp-4-dehydrorhamnose2 reductase from sulfolobus tokodaii
59c3iusB_
not modelled 100.0 18 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized conserved protein;
PDBTitle: the structure of a functionally unknown conserved protein2 from silicibacter pomeroyi dss
60c3e48B_
not modelled 100.0 15 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative nucleoside-diphosphate-sugar epimerase;
PDBTitle: crystal structure of a nucleoside-diphosphate-sugar epimerase2 (sav0421) from staphylococcus aureus, northeast structural genomics3 consortium target zr319
61c2gn9B_
not modelled 99.9 16 PDB header:lyase
Chain: B: PDB Molecule:udp-glcnac c6 dehydratase;
PDBTitle: crystal structure of udp-glcnac inverting 4,6-dehydratase in complex2 with nadp and udp-glc
62c2zklA_
not modelled 99.9 17 PDB header:isomerase
Chain: A: PDB Molecule:capsular polysaccharide synthesis enzyme cap5f;
PDBTitle: crystal structure of capsular polysaccharide assembling protein capf2 from staphylococcus aureus
63d1xgka_
not modelled 99.9 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
64c3i5mA_
not modelled 99.9 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative leucoanthocyanidin reductase 1;
PDBTitle: structure of the apo form of leucoanthocyanidin reductase from vitis2 vinifera
65c2qx7A_
not modelled 99.9 17 PDB header:plant protein
Chain: A: PDB Molecule:eugenol synthase 1;
PDBTitle: structure of eugenol synthase from ocimum basilicum
66c2vrcD_
not modelled 99.9 18 PDB header:oxidoreductase
Chain: D: PDB Molecule:triphenylmethane reductase;
PDBTitle: crystal structure of the citrobacter sp. triphenylmethane2 reductase complexed with nadp(h)
67c2zcuA_
not modelled 99.9 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:uncharacterized oxidoreductase ytfg;
PDBTitle: crystal structure of a new type of nadph-dependent quinone2 oxidoreductase (qor2) from escherichia coli
68d1qyda_
not modelled 99.9 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
69c3nzoB_
not modelled 99.9 21 PDB header:lyase
Chain: B: PDB Molecule:udp-n-acetylglucosamine 4,6-dehydratase;
PDBTitle: udp-n-acetylglucosamine 4,6-dehydratase from vibrio fischeri.
70d1qyca_
not modelled 99.9 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
71c2exxB_
not modelled 99.9 14 PDB header:unknown function
Chain: B: PDB Molecule:hscarg protein;
PDBTitle: crystal structure of hscarg from homo sapiens in complex with nadp
72c2gasA_
not modelled 99.8 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:isoflavone reductase;
PDBTitle: crystal structure of isoflavone reductase
73c3c1oA_
not modelled 99.8 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:eugenol synthase;
PDBTitle: the multiple phenylpropene synthases in both clarkia2 breweri and petunia hybrida represent two distinct lineages
74c3rfxB_
not modelled 99.8 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:uronate dehydrogenase;
PDBTitle: crystal structure of uronate dehydrogenase from agrobacterium2 tumefaciens, y136a mutant complexed with nad
75c3ay3C_
not modelled 99.8 24 PDB header:oxidoreductase
Chain: C: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: crystal structure of glucuronic acid dehydrogeanse from2 chromohalobacter salexigens
76d2q46a1
not modelled 99.7 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
77c3dqpA_
not modelled 99.7 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase ylbe;
PDBTitle: crystal structure of the oxidoreductase ylbe from2 lactococcus lactis, northeast structural genomics3 consortium target kr121.
78c3dhnA_
not modelled 99.7 16 PDB header:isomerase, lyase
Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: crystal structure of the putative epimerase q89z24_bactn2 from bacteroides thetaiotaomicron. northeast structural3 genomics consortium target btr310.
79c3e8xA_
not modelled 99.7 15 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative nad-dependent epimerase/dehydratase;
PDBTitle: putative nad-dependent epimerase/dehydratase from bacillus halodurans.
80c3h2sA_
not modelled 99.7 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative nadh-flavin reductase;
PDBTitle: crystal structure of the q03b84 protein from lactobacillus2 casei. northeast structural genomics consortium target3 lcr19.
81d1hdoa_
not modelled 99.6 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
82c3qvoA_
not modelled 99.6 13 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:nmra family protein;
PDBTitle: structure of a rossmann-fold nad(p)-binding family protein from2 shigella flexneri.
83d2bkaa1
not modelled 99.4 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
84c3ew7A_
not modelled 99.4 14 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:lmo0794 protein;
PDBTitle: crystal structure of the lmo0794 protein from listeria2 monocytogenes. northeast structural genomics consortium3 target lmr162.
85d2a35a1
not modelled 99.4 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
86d2fmua1
not modelled 99.3 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
87d1mlda1
not modelled 99.1 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
88c3v8bC_
not modelled 99.1 13 PDB header:oxidoreductase
Chain: C: PDB Molecule:putative dehydrogenase, possibly 3-oxoacyl-[acyl-carrier
PDBTitle: crystal structure of a 3-ketoacyl-acp reductase from sinorhizobium2 meliloti 1021
89c2jahB_
not modelled 99.1 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:clavulanic acid dehydrogenase;
PDBTitle: biochemical and structural analysis of the clavulanic acid2 dehydeogenase (cad) from streptomyces clavuligerus
90d1hyea1
not modelled 99.0 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
91c3r6dA_
not modelled 99.0 14 PDB header:lyase, isomerase
Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: crystal structure of nad-dependent epimerase/dehydratase from2 veillonella parvula dsm 2008 with cz-methylated lysine
92d1sbya1
not modelled 99.0 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
93c2qioA_
not modelled 99.0 12 PDB header:unknown function
Chain: A: PDB Molecule:enoyl-(acyl-carrier-protein) reductase;
PDBTitle: x-ray structure of enoyl-acyl carrier protein reductase from bacillus2 anthracis with triclosan
94c3l77A_
not modelled 99.0 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:short-chain alcohol dehydrogenase;
PDBTitle: x-ray structure alcohol dehydrogenase from archaeon thermococcus2 sibiricus complexed with 5-hydroxy-nadp
95c3p19A_
not modelled 99.0 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative blue fluorescent protein;
PDBTitle: improved nadph-dependent blue fluorescent protein
96c3ioyB_
not modelled 98.9 11 PDB header:oxidoreductase
Chain: B: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: structure of putative short-chain dehydrogenase (saro_0793)2 from novosphingobium aromaticivorans
97c3i4fD_
not modelled 98.9 13 PDB header:oxidoreductase
Chain: D: PDB Molecule:3-oxoacyl-[acyl-carrier protein] reductase;
PDBTitle: structure of putative 3-oxoacyl-reductase from bacillus thuringiensis
98c2p68A_
not modelled 98.9 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of aq_1716 from aquifex aeolicus vf5
99c3oidA_
not modelled 98.9 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:enoyl-[acyl-carrier-protein] reductase [nadph];
PDBTitle: crystal structure of enoyl-acp reductases iii (fabl) from b. subtilis2 (complex with nadp and tcl)
100c3toxG_
not modelled 98.9 15 PDB header:oxidoreductase
Chain: G: PDB Molecule:short chain dehydrogenase;
PDBTitle: crystal structure of a short chain dehydrogenase in complex with2 nad(p) from sinorhizobium meliloti 1021
101d1jtva_
not modelled 98.9 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
102d2gdza1
not modelled 98.9 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
103c2cfcB_
not modelled 98.9 12 PDB header:oxidoreductase
Chain: B: PDB Molecule:2-(r)-hydroxypropyl-com dehydrogenase;
PDBTitle: structural basis for stereo selectivity in the (r)- and2 (s)-hydroxypropylethane thiosulfonate dehydrogenases
104c3l6eA_
not modelled 98.9 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase, short-chain dehydrogenase/reductase family;
PDBTitle: crystal structure of putative short chain dehydrogenase/reductase2 family oxidoreductase from aeromonas hydrophila subsp. hydrophila3 atcc 7966
105d1geea_
not modelled 98.9 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
106c2dteB_
not modelled 98.9 12 PDB header:oxidoreductase
Chain: B: PDB Molecule:glucose 1-dehydrogenase related protein;
PDBTitle: structure of thermoplasma acidophilum aldohexose dehydrogenase (aldt)2 in complex with nadh
107c3iccA_
not modelled 98.9 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative 3-oxoacyl-(acyl carrier protein) reductase;
PDBTitle: crystal structure of a putative 3-oxoacyl-(acyl carrier protein)2 reductase from bacillus anthracis at 1.87 a resolution
108d1qsga_
not modelled 98.9 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
109c2vz8B_
not modelled 98.8 13 PDB header:transferase
Chain: B: PDB Molecule:fatty acid synthase;
PDBTitle: crystal structure of mammalian fatty acid synthase
110c3lylB_
not modelled 98.8 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-oxoacyl-(acyl-carrier-protein) reductase;
PDBTitle: structure of 3-oxoacyl-acylcarrier protein reductase, fabg2 from francisella tularensis
111c3d7lG_
not modelled 98.8 16 PDB header:structural genomics, unknown function
Chain: G: PDB Molecule:lin1944 protein;
PDBTitle: the crystal structure of the protein lin1944 from listeria innocua .
112c3grkE_
not modelled 98.8 15 PDB header:oxidoreductase
Chain: E: PDB Molecule:enoyl-(acyl-carrier-protein) reductase (nadh);
PDBTitle: crystal structure of short chain dehydrogenase reductase2 sdr glucose-ribitol dehydrogenase from brucella melitensis
113c3un1D_
not modelled 98.8 13 PDB header:oxidoreductase
Chain: D: PDB Molecule:probable oxidoreductase;
PDBTitle: crystal structure of an oxidoreductase from sinorhizobium meliloti2 1021
114d2pd4a1
not modelled 98.8 11 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
115c3m1aF_
not modelled 98.8 12 PDB header:oxidoreductase
Chain: F: PDB Molecule:putative dehydrogenase;
PDBTitle: the crystal structure of a short-chain dehydrogenase from2 streptomyces avermitilis to 2a
116c2fr1A_
not modelled 98.8 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:erythromycin synthase, eryai;
PDBTitle: the first ketoreductase of the erythromycin synthase2 (crystal form 2)
117c3ijrF_
not modelled 98.8 13 PDB header:oxidoreductase
Chain: F: PDB Molecule:oxidoreductase, short chain dehydrogenase/reductase family;
PDBTitle: 2.05 angstrom resolution crystal structure of a short chain2 dehydrogenase from bacillus anthracis str. 'ames ancestor' in complex3 with nad+
118c2q2qG_
not modelled 98.8 15 PDB header:oxidoreductase
Chain: G: PDB Molecule:beta-d-hydroxybutyrate dehydrogenase;
PDBTitle: structure of d-3-hydroxybutyrate dehydrogenase from pseudomonas putida
119d1y5ma1
not modelled 98.8 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
120d1xu9a_
not modelled 98.8 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0