Phyre 2 Results for P00968

Email	l.a.kelley@imperial.ac.uk
Description	P00968
Date	Thu Jan 5 10:57:25 GMT 2012
Unique Job ID	cdd0a4d2f0e926e0

Summary

Top model

Image coloured by rainbow N → C terminus

Model (left) based on template c1m6vE_

Top template information

PDB header:ligase
Chain: E: PDB Molecule:carbamoyl phosphate synthetase large chain;
PDBTitle: crystal structure of the g359f (small subunit) point mutant of2 carbamoyl phosphate synthetase

Confidence and coverage

Confidence:

100.0%

Coverage:

99%

1059 residues ( 99% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.

3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M P K R T D I K S I L I L G A G P I V I G Q A C E F D Y S G A Q A C K A L R E E G Y R V I L V N S N P A T I M T D P E M

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence A D A T Y I E P I H W E V V R K I I E K E R P D A V L P T M G G Q T A L N C A L E L E R Q G V L E E F G V T M I G A T A

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180

Sequence D A I D K A E D R R R F D V A M K K I G L E T A R S G I A H T M E E A L A V A A D V G F P C I I R P S F T M G G S G G G

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210 . . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240

Sequence I A Y N R E E F E E I C A R G L D L S P T K E L L I D E S L I G W K E Y E M E V V R D K N D N C I I V C S I E N F D A M

Secondary structure

SS confidence

Disorder
? ?

Disorder confidence

. . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280 . . . . . . . . . 290 . . . . . . . . . 300

Sequence G I H T G D S I T V A P A Q T L T D K E Y Q I M R N A S M A V L R E I G V E T G G S N V Q F A V N P K N G R L I V I E M

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350 . . . . . . . . . 360

Sequence N P R V S R S S A L A S K A T G F P I A K V A A K L A V G Y T L D E L M N D I T G G R T P A S F E P S I D Y V V T K I P

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence R F N F E K F A G A N D R L T T Q M K S V G E V M A I G R T Q Q E S L Q K A L R G L E V G A T G F D P K V S L D D P E A

Secondary structure

SS confidence

Disorder
?
?
?

Disorder confidence

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480

Sequence L T K I R R E L K D A G A D R I W Y I A D A F R A G L S V D G V F N L T N I D R W F L V Q I E E L V R L E E K V A E V G

Secondary structure

SS confidence

Disorder
? ?

Disorder confidence

. . . . . . . . . 490 . . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540

Sequence I T G L N A D F L R Q L K R K G F A D A R L A K L A G V R E A E I R K L R D Q Y D L H P V Y K R V D T C A A E F A T D T

Secondary structure

SS confidence

Disorder ?

Disorder confidence

. . . . . . . . . 550 . . . . . . . . . 560 . . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600

Sequence A Y M Y S T Y E E E C E A N P S T D R E K I M V L G G G P N R I G Q G I E F D Y C C V H A S L A L R E D G Y E T I M V N

Secondary structure

SS confidence

Disorder
?
? ? ? ?
?
? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630 . . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660

Sequence C N P E T V S T D Y D T S D R L Y F E P V T L E D V L E I V R I E K P K G V I V Q Y G G Q T P L K L A R A L E A A G V P

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700 . . . . . . . . . 710 . . . . . . . . . 720

Sequence V I G T S P D A I D R A E D R E R F Q H A V E R L K L K Q P A N A T V T A I E M A V E K A K E I G Y P L V V R P S Y V L

Secondary structure

SS confidence

Disorder
? ? ? ?

Disorder confidence

. . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770 . . . . . . . . . 780

Sequence G G R A M E I V Y D E A D L R R Y F Q T A V S V S N D A P V L L D H F L D D A V E V D V D A I C D G E M V L I G G I M E

Secondary structure

SS confidence

Disorder ? ?

Disorder confidence

. . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence H I E Q A G V H S G D S A C S L P A Y T L S Q E I Q D V M R Q Q V Q K L A F E L Q V R G L M N V Q F A V K N N E V Y L I

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900

Sequence E V N P R A A R T V P F V S K A T G V P L A K V A A R V M A G K S L A E Q G V T K E V I P P Y Y S V K E V V L P F N K F

Secondary structure

SS confidence

Disorder
?
? ?

Disorder confidence

. . . . . . . . . 910 . . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960

Sequence P G V D P L L G P E M R S T G E V M G V G R T F A E A F A K A Q L G S N S T M K K H G R A L L S V R E G D K E R V V D L

Secondary structure

SS confidence

Disorder
? ? ? ? ? ?
? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 970 . . . . . . . . . 980 . . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . . 1010 . . . . . . . . . 1020

Sequence A A K L L K Q G F E L D A T H G T A I V L G E A G I N P R L V N K V H E G R P H I Q D R I K N G E Y T Y I I N T T S G R

Secondary structure

SS confidence

Disorder
? ? ?
? ?

Disorder confidence

. . . . . . . . . 1030 . . . . . . . . . 1040 . . . . . . . . . 1050 . . . . . . . . . 1060 . . . . . . . . . 1070 . . .

Sequence R A I E D S R V I R R S A L Q Y K V H Y D T T L N G G F A T A M A L N A D A T E K V I S V Q E M H A Q I K

Secondary structure

SS confidence

Disorder ? ? ? ? ?
? ? ? ? ? ? ?
?
? ? ? ? ? ? ? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered

Alpha helix

Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

PDB 1m6v chain E

Region: 1 - 1073
Aligned: 1059
Modelled: 1073
Confidence: 100.0%
Identity: 100%
PDB header:ligase
Chain: E: PDB Molecule:carbamoyl phosphate synthetase large chain;
PDBTitle: crystal structure of the g359f (small subunit) point mutant of2 carbamoyl phosphate synthetase

Phyre2

PDB 3u9s chain E

Region: 5 - 564
Aligned: 514
Modelled: 545
Confidence: 100.0%
Identity: 18%
PDB header:ligase
Chain: E: PDB Molecule:methylcrotonyl-coa carboxylase, alpha-subunit;
PDBTitle: crystal structure of p. aeruginosa 3-methylcrotonyl-coa carboxylase2 (mcc) 750 kd holoenzyme, coa complex

Phyre2

PDB 3bg5 chain C

Region: 6 - 431
Aligned: 393
Modelled: 412
Confidence: 100.0%
Identity: 22%
PDB header:ligase
Chain: C: PDB Molecule:pyruvate carboxylase;
PDBTitle: crystal structure of staphylococcus aureus pyruvate2 carboxylase

Phyre2

PDB 1w96 chain B

Region: 5 - 403
Aligned: 382
Modelled: 396
Confidence: 100.0%
Identity: 20%
PDB header:ligase
Chain: B: PDB Molecule:acetyl-coenzyme a carboxylase;
PDBTitle: crystal structure of biotin carboxylase domain of acetyl-2 coenzyme a carboxylase from saccharomyces cerevisiae in3 complex with soraphen a

Phyre2

PDB 2hjw chain A

Region: 4 - 403
Aligned: 380
Modelled: 386
Confidence: 100.0%
Identity: 19%
PDB header:ligase
Chain: A: PDB Molecule:acetyl-coa carboxylase 2;
PDBTitle: crystal structure of the bc domain of acc2

Phyre2

PDB 3g8c chain B

Region: 7 - 455
Aligned: 410
Modelled: 433
Confidence: 100.0%
Identity: 23%
PDB header:ligase
Chain: B: PDB Molecule:biotin carboxylase;
PDBTitle: crystal stucture of biotin carboxylase in complex with2 biotin, bicarbonate, adp and mg ion

Phyre2

PDB 2vpq chain A

Region: 8 - 431
Aligned: 397
Modelled: 408
Confidence: 100.0%
Identity: 22%
PDB header:ligase
Chain: A: PDB Molecule:acetyl-coa carboxylase;
PDBTitle: crystal structure of biotin carboxylase from s. aureus2 complexed with amppnp

Phyre2

PDB 3n6r chain K

Region: 8 - 431
Aligned: 386
Modelled: 403
Confidence: 100.0%
Identity: 21%
PDB header:ligase
Chain: K: PDB Molecule:propionyl-coa carboxylase, alpha subunit;
PDBTitle: crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc)

Phyre2

PDB 3ouz chain A

Region: 5 - 403
Aligned: 379
Modelled: 384
Confidence: 100.0%
Identity: 22%
PDB header:ligase
Chain: A: PDB Molecule:biotin carboxylase;
PDBTitle: crystal structure of biotin carboxylase-adp complex from campylobacter2 jejuni

Phyre2

PDB 1ulz chain A

Region: 7 - 431
Aligned: 397
Modelled: 411
Confidence: 100.0%
Identity: 24%
PDB header:ligase
Chain: A: PDB Molecule:pyruvate carboxylase n-terminal domain;
PDBTitle: crystal structure of the biotin carboxylase subunit of pyruvate2 carboxylase

Phyre2

PDB 2dzd chain B

Region: 5 - 403
Aligned: 376
Modelled: 396
Confidence: 100.0%
Identity: 24%
PDB header:ligase
Chain: B: PDB Molecule:pyruvate carboxylase;
PDBTitle: crystal structure of the biotin carboxylase domain of2 pyruvate carboxylase

Phyre2

PDB 2gpw chain C

Region: 7 - 431
Aligned: 391
Modelled: 409
Confidence: 100.0%
Identity: 23%
PDB header:ligase
Chain: C: PDB Molecule:biotin carboxylase;
PDBTitle: crystal structure of the biotin carboxylase subunit, f363a2 mutant, of acetyl-coa carboxylase from escherichia coli.

Phyre2

PDB 3gid chain B

Region: 5 - 403
Aligned: 369
Modelled: 388
Confidence: 100.0%
Identity: 20%
PDB header:ligase
Chain: B: PDB Molecule:acetyl-coa carboxylase 2;
PDBTitle: the biotin carboxylase (bc) domain of human acetyl-coa2 carboxylase 2 (acc2) in complex with soraphen a

Phyre2

PDB 1a9x chain A domain 5

Region: 128 - 402
Aligned: 275
Modelled: 275
Confidence: 100.0%
Identity: 100%
Fold: ATP-grasp
Superfamily: Glutathione synthetase ATP-binding domain-like
Family: BC ATP-binding domain-like

Phyre2

PDB 2qf7 chain A

Region: 6 - 431
Aligned: 332
Modelled: 356
Confidence: 100.0%
Identity: 20%
PDB header:ligase
Chain: A: PDB Molecule:pyruvate carboxylase protein;
PDBTitle: crystal structure of a complete multifunctional pyruvate carboxylase2 from rhizobium etli

Phyre2

PDB 2xd4 chain A

Region: 561 - 934
Aligned: 356
Modelled: 364
Confidence: 100.0%
Identity: 17%
PDB header:ligase
Chain: A: PDB Molecule:phosphoribosylamine--glycine ligase;
PDBTitle: nucleotide-bound structures of bacillus subtilis glycinamide2 ribonucleotide synthetase

Phyre2

PDB 1kjj chain A

Region: 2 - 403
Aligned: 368
Modelled: 395
Confidence: 100.0%
Identity: 16%
PDB header:transferase
Chain: A: PDB Molecule:phosphoribosylglycinamide formyltransferase 2;
PDBTitle: crystal structure of glycniamide ribonucleotide2 transformylase in complex with mg-atp-gamma-s

Phyre2

PDB 2qk4 chain A

Region: 557 - 934
Aligned: 359
Modelled: 378
Confidence: 100.0%
Identity: 16%
PDB header:ligase
Chain: A: PDB Molecule:trifunctional purine biosynthetic protein adenosine-3;
PDBTitle: human glycinamide ribonucleotide synthetase

Phyre2

PDB 2ip4 chain A

Region: 560 - 936
Aligned: 360
Modelled: 376
Confidence: 100.0%
Identity: 18%
PDB header:ligase
Chain: A: PDB Molecule:phosphoribosylamine--glycine ligase;
PDBTitle: crystal structure of glycinamide ribonucleotide synthetase from2 thermus thermophilus hb8

Phyre2

PDB 3lp8 chain A

Region: 561 - 937
Aligned: 361
Modelled: 366
Confidence: 100.0%
Identity: 18%
PDB header:ligase
Chain: A: PDB Molecule:phosphoribosylamine-glycine ligase;
PDBTitle: crystal structure of phosphoribosylamine-glycine ligase from2 ehrlichia chaffeensis

Phyre2

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Detailed template information

#	Template	Alignment Coverage	3D Model	Confidence	% i.d.	Template Information

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server

Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]

If you use the binding site predictions from 3DLigandSite, please also cite:

3DLigandSite: predicting ligand-binding sites using similar structures.

Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]

Imperial College London

Lawrence Kelley, Benjamin Jefferys

Disclaimer

Terms and Conditions

Component software

Template detection: HHpred 1.51

Secondary structure prediction: Psi-pred 2.5

Disorder prediction: Disopred 2.4

Transmembrane prediction: Memsat_SVM

Multi-template modelling and ab initio: Poing 1.0

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence	M	P	K	R	T	D	I	K	S	I	L	I	L	G	A	G	P	I	V	I	G	Q	A	C	E	F	D	Y	S	G	A	Q	A	C	K	A	L	R	E	E	G	Y	R	V	I	L	V	N	S	N	P	A	T	I	M	T	D	P	E	M
Secondary structure
SS confidence
Disorder	?	?	?	?	?	?	?																			?
Disorder confidence

	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence	A	D	A	T	Y	I	E	P	I	H	W	E	V	V	R	K	I	I	E	K	E	R	P	D	A	V	L	P	T	M	G	G	Q	T	A	L	N	C	A	L	E	L	E	R	Q	G	V	L	E	E	F	G	V	T	M	I	G	A	T	A
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence	D	A	I	D	K	A	E	D	R	R	R	F	D	V	A	M	K	K	I	G	L	E	T	A	R	S	G	I	A	H	T	M	E	E	A	L	A	V	A	A	D	V	G	F	P	C	I	I	R	P	S	F	T	M	G	G	S	G	G	G
Secondary structure
SS confidence
Disorder																																																			?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence	I	A	Y	N	R	E	E	F	E	E	I	C	A	R	G	L	D	L	S	P	T	K	E	L	L	I	D	E	S	L	I	G	W	K	E	Y	E	M	E	V	V	R	D	K	N	D	N	C	I	I	V	C	S	I	E	N	F	D	A	M
Secondary structure
SS confidence
Disorder																				?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence	G	I	H	T	G	D	S	I	T	V	A	P	A	Q	T	L	T	D	K	E	Y	Q	I	M	R	N	A	S	M	A	V	L	R	E	I	G	V	E	T	G	G	S	N	V	Q	F	A	V	N	P	K	N	G	R	L	I	V	I	E	M
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence	N	P	R	V	S	R	S	S	A	L	A	S	K	A	T	G	F	P	I	A	K	V	A	A	K	L	A	V	G	Y	T	L	D	E	L	M	N	D	I	T	G	G	R	T	P	A	S	F	E	P	S	I	D	Y	V	V	T	K	I	P
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	R	F	N	F	E	K	F	A	G	A	N	D	R	L	T	T	Q	M	K	S	V	G	E	V	M	A	I	G	R	T	Q	Q	E	S	L	Q	K	A	L	R	G	L	E	V	G	A	T	G	F	D	P	K	V	S	L	D	D	P	E	A
Secondary structure
SS confidence
Disorder									?						?																																											?
Disorder confidence

	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence	L	T	K	I	R	R	E	L	K	D	A	G	A	D	R	I	W	Y	I	A	D	A	F	R	A	G	L	S	V	D	G	V	F	N	L	T	N	I	D	R	W	F	L	V	Q	I	E	E	L	V	R	L	E	E	K	V	A	E	V	G
Secondary structure
SS confidence
Disorder																																																											?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence	I	T	G	L	N	A	D	F	L	R	Q	L	K	R	K	G	F	A	D	A	R	L	A	K	L	A	G	V	R	E	A	E	I	R	K	L	R	D	Q	Y	D	L	H	P	V	Y	K	R	V	D	T	C	A	A	E	F	A	T	D	T
Secondary structure
SS confidence
Disorder	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence	A	Y	M	Y	S	T	Y	E	E	E	C	E	A	N	P	S	T	D	R	E	K	I	M	V	L	G	G	G	P	N	R	I	G	Q	G	I	E	F	D	Y	C	C	V	H	A	S	L	A	L	R	E	D	G	Y	E	T	I	M	V	N
Secondary structure
SS confidence
Disorder									?		?	?	?	?		?												?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660
Sequence	C	N	P	E	T	V	S	T	D	Y	D	T	S	D	R	L	Y	F	E	P	V	T	L	E	D	V	L	E	I	V	R	I	E	K	P	K	G	V	I	V	Q	Y	G	G	Q	T	P	L	K	L	A	R	A	L	E	A	A	G	V	P
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720
Sequence	V	I	G	T	S	P	D	A	I	D	R	A	E	D	R	E	R	F	Q	H	A	V	E	R	L	K	L	K	Q	P	A	N	A	T	V	T	A	I	E	M	A	V	E	K	A	K	E	I	G	Y	P	L	V	V	R	P	S	Y	V	L
Secondary structure
SS confidence
Disorder																																																									?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780
Sequence	G	G	R	A	M	E	I	V	Y	D	E	A	D	L	R	R	Y	F	Q	T	A	V	S	V	S	N	D	A	P	V	L	L	D	H	F	L	D	D	A	V	E	V	D	V	D	A	I	C	D	G	E	M	V	L	I	G	G	I	M	E
Secondary structure
SS confidence
Disorder	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	H	I	E	Q	A	G	V	H	S	G	D	S	A	C	S	L	P	A	Y	T	L	S	Q	E	I	Q	D	V	M	R	Q	Q	V	Q	K	L	A	F	E	L	Q	V	R	G	L	M	N	V	Q	F	A	V	K	N	N	E	V	Y	L	I
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900
Sequence	E	V	N	P	R	A	A	R	T	V	P	F	V	S	K	A	T	G	V	P	L	A	K	V	A	A	R	V	M	A	G	K	S	L	A	E	Q	G	V	T	K	E	V	I	P	P	Y	Y	S	V	K	E	V	V	L	P	F	N	K	F
Secondary structure
SS confidence
Disorder																																					?		?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960
Sequence	P	G	V	D	P	L	L	G	P	E	M	R	S	T	G	E	V	M	G	V	G	R	T	F	A	E	A	F	A	K	A	Q	L	G	S	N	S	T	M	K	K	H	G	R	A	L	L	S	V	R	E	G	D	K	E	R	V	V	D	L
Secondary structure
SS confidence
Disorder										?	?	?	?	?	?																				?	?	?	?	?		?
Disorder confidence

	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020
Sequence	A	A	K	L	L	K	Q	G	F	E	L	D	A	T	H	G	T	A	I	V	L	G	E	A	G	I	N	P	R	L	V	N	K	V	H	E	G	R	P	H	I	Q	D	R	I	K	N	G	E	Y	T	Y	I	I	N	T	T	S	G	R
Secondary structure
SS confidence
Disorder																																				?	?	?																					?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.
Sequence	R	A	I	E	D	S	R	V	I	R	R	S	A	L	Q	Y	K	V	H	Y	D	T	T	L	N	G	G	F	A	T	A	M	A	L	N	A	D	A	T	E	K	V	I	S	V	Q	E	M	H	A	Q	I	K
Secondary structure
SS confidence
Disorder	?	?	?	?	?																															?	?	?	?	?	?	?		?		?	?	?	?	?	?	?	?
Disorder confidence