Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	E	L	L	L	G	V	N	I	D	H	I	A	T	L	R	N	A	R	G	T	A	Y	P	D	P	V	Q	A	A	F	I	A	E	Q	A	G	A	D	G	I	T	V	H	L	R	E	D	R	R	H	I	T	D	R	D	V	R	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?														?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	R	Q	T	L	D	T	R	M	N	L	E	M	A	V	T	E	E	M	L	A	I	A	V	E	T	K	P	H	F	C	C	L	V	P	E	K	R	Q	E	V	T	T	E	G	G	L	D	V	A	G	Q	R	D	K	M	R	D	A	C
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		K	R	L	A	D	A	G	I	Q	V	S	L	F	I	D	A	D	E	E	Q	I	K	A	A	A	E	V	G	A	P	F	I	E	I	H	T	G	C	Y	A	D	A	K	T	D	A	E	Q	A	Q	E	L	A	R	I	A	K	A	A	T
Secondary structure
SS confidence
Disorder																																													?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		F	A	A	S	L	G	L	K	V	N	A	G	H	G	L	T	Y	H	N	V	K	A	I	A	A	I	P	E	M	H	E	L	N	I	G	H	A	I	I	G	R	A	V	M	T	G	L	K	D	A	V	A	E	M	K	R	L	M	L	E
Secondary structure
SS confidence
Disorder																												?																																	?
Disorder confidence
		.	.	.
Sequence		A	R	G
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1m5w chain A Region: 2 - 243 Aligned: 242 Modelled: 242 Confidence: 100.0% Identity: 100% Fold: TIM beta/alpha-barrel Superfamily: Pyridoxine 5'-phosphate synthase Family: Pyridoxine 5'-phosphate synthase Phyre2 PDB 3gk0 chain H Region: 2 - 242 Aligned: 241 Modelled: 241 Confidence: 100.0% Identity: 67% PDB header:transferase Chain: H: PDB Molecule:pyridoxine 5'-phosphate synthase; PDBTitle: crystal structure of pyridoxal phosphate biosynthetic2 protein from burkholderia pseudomallei Phyre2 PDB 3o6c chain A Region: 4 - 240 Aligned: 234 Modelled: 236 Confidence: 100.0% Identity: 48% PDB header:transferase Chain: A: PDB Molecule:pyridoxine 5'-phosphate synthase; PDBTitle: pyridoxal phosphate biosynthetic protein pdxj from campylobacter2 jejuni Phyre2 PDB 3igs chain B Region: 25 - 242 Aligned: 184 Modelled: 217 Confidence: 98.3% Identity: 16% PDB header:isomerase Chain: B: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase 2; PDBTitle: structure of the salmonella enterica n-acetylmannosamine-6-phosphate2 2-epimerase Phyre2 PDB 3qja chain A Region: 24 - 219 Aligned: 174 Modelled: 183 Confidence: 97.9% Identity: 16% PDB header:lyase Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase; PDBTitle: crystal structure of the mycobacterium tuberculosis indole-3-glycerol2 phosphate synthase (trpc) in apo form Phyre2 PDB 2fli chain A domain 1 Region: 3 - 238 Aligned: 207 Modelled: 212 Confidence: 97.8% Identity: 13% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: D-ribulose-5-phosphate 3-epimerase Phyre2 PDB 1yxy chain A domain 1 Region: 20 - 219 Aligned: 176 Modelled: 200 Confidence: 97.8% Identity: 18% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: NanE-like Phyre2 PDB 3q58 chain A Region: 25 - 240 Aligned: 182 Modelled: 202 Confidence: 97.6% Identity: 16% PDB header:isomerase Chain: A: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase; PDBTitle: structure of n-acetylmannosamine-6-phosphate epimerase from salmonella2 enterica Phyre2 PDB 3lot chain C Region: 27 - 192 Aligned: 166 Modelled: 164 Confidence: 97.4% Identity: 21% PDB header:structure genomics, unknown function Chain: C: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of protein of unknown function (np_070038.1) from2 archaeoglobus fulgidus at 1.89 a resolution Phyre2 PDB 3gr7 chain A Region: 28 - 221 Aligned: 146 Modelled: 149 Confidence: 97.4% Identity: 18% PDB header:oxidoreductase Chain: A: PDB Molecule:nadph dehydrogenase; PDBTitle: structure of oye from geobacillus kaustophilus, hexagonal2 crystal form Phyre2 PDB 1xcf chain A Region: 22 - 239 Aligned: 192 Modelled: 194 Confidence: 97.3% Identity: 19% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: Tryptophan biosynthesis enzymes Phyre2 PDB 3e02 chain A Region: 27 - 148 Aligned: 122 Modelled: 122 Confidence: 97.3% Identity: 20% PDB header:metal binding protein Chain: A: PDB Molecule:uncharacterized protein duf849; PDBTitle: crystal structure of a duf849 family protein (bxe_c0271) from2 burkholderia xenovorans lb400 at 1.90 a resolution Phyre2 PDB 1tqj chain A Region: 3 - 239 Aligned: 207 Modelled: 222 Confidence: 97.3% Identity: 13% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: D-ribulose-5-phosphate 3-epimerase Phyre2 PDB 1vc4 chain A Region: 26 - 219 Aligned: 174 Modelled: 180 Confidence: 97.3% Identity: 21% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: Tryptophan biosynthesis enzymes Phyre2 PDB 2c3z chain A Region: 19 - 219 Aligned: 178 Modelled: 188 Confidence: 97.2% Identity: 15% PDB header:lyase Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase; PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus Phyre2 PDB 1rd5 chain A Region: 22 - 239 Aligned: 196 Modelled: 203 Confidence: 97.1% Identity: 20% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: Tryptophan biosynthesis enzymes Phyre2 PDB 1wv2 chain A Region: 22 - 242 Aligned: 198 Modelled: 215 Confidence: 97.1% Identity: 16% Fold: TIM beta/alpha-barrel Superfamily: ThiG-like Family: ThiG-like Phyre2 PDB 1wbh chain A domain 1 Region: 1 - 239 Aligned: 204 Modelled: 228 Confidence: 97.1% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 1q6o chain A Region: 27 - 234 Aligned: 140 Modelled: 145 Confidence: 97.0% Identity: 22% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: Decarboxylase Phyre2 PDB 3inp chain A Region: 22 - 240 Aligned: 197 Modelled: 204 Confidence: 96.8% Identity: 15% PDB header:isomerase Chain: A: PDB Molecule:d-ribulose-phosphate 3-epimerase; PDBTitle: 2.05 angstrom resolution crystal structure of d-ribulose-phosphate 3-2 epimerase from francisella tularensis. Phyre2 1 d1m5wa_ 2 c3gk0H_ 3 c3o6cA_ 4 c3igsB_ 5 c3qjaA_ 6 d2flia1 7 d1yxya1 8 c3q58A_ 9 c3lotC_ 10 c3gr7A_ 11 d1xcfa_ 12 c3e02A_ 13 d1tqja_ 14 d1vc4a_ 15 c2c3zA_ 16 d1rd5a_ 17 d1wv2a_ 18 d1wbha1 19 d1q6oa_ 20 c3inpA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1m5wa_ 100.0 100 Fold:TIM beta/alpha-barrel Superfamily:Pyridoxine 5'-phosphate synthase Family:Pyridoxine 5'-phosphate synthase 2 c3gk0H_ 100.0 67 PDB header:transferase Chain: H: PDB Molecule:pyridoxine 5'-phosphate synthase; PDBTitle: crystal structure of pyridoxal phosphate biosynthetic2 protein from burkholderia pseudomallei 3 c3o6cA_ 100.0 48 PDB header:transferase Chain: A: PDB Molecule:pyridoxine 5'-phosphate synthase; PDBTitle: pyridoxal phosphate biosynthetic protein pdxj from campylobacter2 jejuni 4 c3igsB_ 98.3 16 PDB header:isomerase Chain: B: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase 2; PDBTitle: structure of the salmonella enterica n-acetylmannosamine-6-phosphate2 2-epimerase 5 c3qjaA_ 97.9 16 PDB header:lyase Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase; PDBTitle: crystal structure of the mycobacterium tuberculosis indole-3-glycerol2 phosphate synthase (trpc) in apo form 6 d2flia1 97.8 13 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 7 d1yxya1 97.8 18 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:NanE-like 8 c3q58A_ 97.6 16 PDB header:isomerase Chain: A: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase; PDBTitle: structure of n-acetylmannosamine-6-phosphate epimerase from salmonella2 enterica 9 c3lotC_ 97.4 21 PDB header:structure genomics, unknown function Chain: C: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of protein of unknown function (np_070038.1) from2 archaeoglobus fulgidus at 1.89 a resolution 10 c3gr7A_ 97.4 18 PDB header:oxidoreductase Chain: A: PDB Molecule:nadph dehydrogenase; PDBTitle: structure of oye from geobacillus kaustophilus, hexagonal2 crystal form 11 d1xcfa_ 97.3 19 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 12 c3e02A_ 97.3 20 PDB header:metal binding protein Chain: A: PDB Molecule:uncharacterized protein duf849; PDBTitle: crystal structure of a duf849 family protein (bxe_c0271) from2 burkholderia xenovorans lb400 at 1.90 a resolution 13 d1tqja_ 97.3 13 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 14 d1vc4a_ 97.3 21 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 15 c2c3zA_ 97.2 15 PDB header:lyase Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase; PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus 16 d1rd5a_ 97.1 20 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 17 d1wv2a_ 97.1 16 Fold:TIM beta/alpha-barrel Superfamily:ThiG-like Family:ThiG-like 18 d1wbha1 97.1 15 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 19 d1q6oa_ 97.0 22 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Decarboxylase 20 c3inpA_ 96.8 15 PDB header:isomerase Chain: A: PDB Molecule:d-ribulose-phosphate 3-epimerase; PDBTitle: 2.05 angstrom resolution crystal structure of d-ribulose-phosphate 3-2 epimerase from francisella tularensis. 21 c3hf3A_ not modelled 96.8 20 PDB header:oxidoreductase Chain: A: PDB Molecule:chromate reductase; PDBTitle: old yellow enzyme from thermus scotoductus sa-01 22 d1rpxa_ not modelled 96.8 13 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 23 d1h1ya_ not modelled 96.8 12 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 24 c3c6cA_ not modelled 96.7 23 PDB header:hydrolase Chain: A: PDB Molecule:3-keto-5-aminohexanoate cleavage enzyme; PDBTitle: crystal structure of a putative 3-keto-5-aminohexanoate cleavage2 enzyme (reut_c6226) from ralstonia eutropha jmp134 at 1.72 a3 resolution 25 c3e49A_ not modelled 96.7 25 PDB header:metal binding protein Chain: A: PDB Molecule:uncharacterized protein duf849 with a tim barrel fold; PDBTitle: crystal structure of a prokaryotic domain of unknown function (duf849)2 with a tim barrel fold (bxe_c0966) from burkholderia xenovorans lb4003 at 1.75 a resolution 26 c3ct7E_ not modelled 96.6 14 PDB header:isomerase Chain: E: PDB Molecule:d-allulose-6-phosphate 3-epimerase; PDBTitle: crystal structure of d-allulose 6-phosphate 3-epimerase2 from escherichia coli k-12 27 d1y0ea_ not modelled 96.6 20 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:NanE-like 28 d1thfd_ not modelled 96.4 11 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Histidine biosynthesis enzymes 29 d1tqxa_ not modelled 96.3 11 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 30 c2v82A_ not modelled 96.2 14 PDB header:lyase Chain: A: PDB Molecule:2-dehydro-3-deoxy-6-phosphogalactonate aldolase; PDBTitle: kdpgal complexed to kdpgal 31 c2htmB_ not modelled 96.1 16 PDB header:biosynthetic protein Chain: B: PDB Molecule:thiazole biosynthesis protein thig; PDBTitle: crystal structure of ttha0676 from thermus thermophilus hb8 32 c3l5aA_ not modelled 95.9 13 PDB header:oxidoreductase Chain: A: PDB Molecule:nadh/flavin oxidoreductase/nadh oxidase; PDBTitle: crystal structure of a probable nadh-dependent flavin oxidoreductase2 from staphylococcus aureus 33 c2y7eA_ not modelled 95.9 19 PDB header:lyase Chain: A: PDB Molecule:3-keto-5-aminohexanoate cleavage enzyme; PDBTitle: crystal structure of the 3-keto-5-aminohexanoate cleavage enzyme2 (kce) from candidatus cloacamonas acidaminovorans (tetragonal form) 34 d1wa3a1 not modelled 95.9 13 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 35 d1i4na_ not modelled 95.7 14 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 36 c2h90A_ not modelled 95.6 16 PDB header:oxidoreductase Chain: A: PDB Molecule:xenobiotic reductase a; PDBTitle: xenobiotic reductase a in complex with coumarin 37 d1j5ta_ not modelled 95.5 11 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 38 c2bdqA_ not modelled 95.4 19 PDB header:metal transport Chain: A: PDB Molecule:copper homeostasis protein cutc; PDBTitle: crystal structure of the putative copper homeostasis2 protein cutc from streptococcus agalactiae, northeast3 strucural genomics target sar15. 39 d1a53a_ not modelled 95.3 16 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 40 d1tv5a1 not modelled 95.2 14 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 41 c1tv5A_ not modelled 95.2 14 PDB header:oxidoreductase Chain: A: PDB Molecule:dihydroorotate dehydrogenase homolog, mitochondrial; PDBTitle: plasmodium falciparum dihydroorotate dehydrogenase with a bound2 inhibitor 42 c3chvA_ not modelled 95.1 15 PDB header:metal binding protein Chain: A: PDB Molecule:prokaryotic domain of unknown function (duf849) with a tim PDBTitle: crystal structure of a prokaryotic domain of unknown function (duf849)2 member (spoa0042) from silicibacter pomeroyi dss-3 at 1.45 a3 resolution 43 d1piia2 not modelled 95.1 19 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 44 d1vhca_ not modelled 95.1 22 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 45 c3ajxA_ not modelled 95.1 19 PDB header:lyase Chain: A: PDB Molecule:3-hexulose-6-phosphate synthase; PDBTitle: crystal structure of 3-hexulose-6-phosphate synthase 46 c3jr2D_ not modelled 95.1 20 PDB header:biosynthetic protein Chain: D: PDB Molecule:hexulose-6-phosphate synthase sgbh; PDBTitle: x-ray crystal structure of the mg-bound 3-keto-l-gulonate-6-phosphate2 decarboxylase from vibrio cholerae o1 biovar el tor str. n16961 47 c3f4wA_ not modelled 95.0 14 PDB header:synthase, lyase Chain: A: PDB Molecule:putative hexulose 6 phosphate synthase; PDBTitle: the 1.65a crystal structure of 3-hexulose-6-phosphate2 synthase from salmonella typhimurium 48 d1z41a1 not modelled 94.9 18 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 49 c3cixA_ not modelled 94.8 21 PDB header:adomet binding protein Chain: A: PDB Molecule:fefe-hydrogenase maturase; PDBTitle: x-ray structure of the [fefe]-hydrogenase maturase hyde from2 thermotoga maritima in complex with thiocyanate 50 d1q45a_ not modelled 94.7 13 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 51 d1bxca_ not modelled 94.7 21 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 52 c3dx5A_ not modelled 94.7 18 PDB header:lyase Chain: A: PDB Molecule:uncharacterized protein asbf; PDBTitle: crystal structure of the probable 3-dhs dehydratase asbf involved in2 the petrobactin synthesis from bacillus anthracis 53 c3thaB_ not modelled 94.5 16 PDB header:lyase Chain: B: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: tryptophan synthase subunit alpha from campylobacter jejuni. 54 d1vyra_ not modelled 94.5 18 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 55 d1qt1a_ not modelled 94.5 19 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 56 d1muwa_ not modelled 94.4 18 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 57 c2fptA_ not modelled 94.4 19 PDB header:oxidoreductase Chain: A: PDB Molecule:dihydroorotate dehydrogenase, mitochondrial; PDBTitle: dual binding mode of a novel series of dhodh inhibitors 58 c3qc3B_ not modelled 94.1 13 PDB header:isomerase Chain: B: PDB Molecule:d-ribulose-5-phosphate-3-epimerase; PDBTitle: crystal structure of a d-ribulose-5-phosphate-3-epimerase (np_954699)2 from homo sapiens at 2.20 a resolution 59 c1ps9A_ not modelled 94.0 15 PDB header:oxidoreductase Chain: A: PDB Molecule:2,4-dienoyl-coa reductase; PDBTitle: the crystal structure and reaction mechanism of e. coli 2,4-2 dienoyl coa reductase 60 d1xima_ not modelled 93.9 22 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 61 c3exsB_ not modelled 93.8 21 PDB header:lyase Chain: B: PDB Molecule:rmpd (hexulose-6-phosphate synthase); PDBTitle: crystal structure of kgpdc from streptococcus mutans in2 complex with d-r5p 62 d1h5ya_ not modelled 93.8 17 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Histidine biosynthesis enzymes 63 d1xi3a_ not modelled 93.7 15 Fold:TIM beta/alpha-barrel Superfamily:Thiamin phosphate synthase Family:Thiamin phosphate synthase 64 d1f76a_ not modelled 93.7 18 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 65 c1yadD_ not modelled 93.5 16 PDB header:transcription Chain: D: PDB Molecule:regulatory protein teni; PDBTitle: structure of teni from bacillus subtilis 66 d1ka9f_ not modelled 93.5 16 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Histidine biosynthesis enzymes 67 d1vhna_ not modelled 93.3 18 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 68 c3kruC_ not modelled 93.2 12 PDB header:oxidoreductase Chain: C: PDB Molecule:nadh:flavin oxidoreductase/nadh oxidase; PDBTitle: crystal structure of the thermostable old yellow enzyme from2 thermoanaerobacter pseudethanolicus e39 69 d1r30a_ not modelled 93.2 11 Fold:TIM beta/alpha-barrel Superfamily:Radical SAM enzymes Family:Biotin synthase 70 c1r30A_ not modelled 93.2 11 PDB header:transferase Chain: A: PDB Molecule:biotin synthase; PDBTitle: the crystal structure of biotin synthase, an s-2 adenosylmethionine-dependent radical enzyme 71 d1djqa1 not modelled 93.2 17 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 72 c3no5C_ not modelled 93.2 20 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a pfam duf849 domain containing protein2 (reut_a1631) from ralstonia eutropha jmp134 at 1.90 a resolution 73 c3gkaB_ not modelled 93.2 31 PDB header:oxidoreductase Chain: B: PDB Molecule:n-ethylmaleimide reductase; PDBTitle: crystal structure of n-ethylmaleimidine reductase from2 burkholderia pseudomallei 74 c1xrsB_ not modelled 93.0 19 PDB header:isomerase Chain: B: PDB Molecule:d-lysine 5,6-aminomutase beta subunit; PDBTitle: crystal structure of lysine 5,6-aminomutase in complex with plp,2 cobalamin, and 5'-deoxyadenosine 75 c3qxbB_ not modelled 93.0 24 PDB header:isomerase Chain: B: PDB Molecule:putative xylose isomerase; PDBTitle: crystal structure of a putative xylose isomerase (yp_426450.1) from2 rhodospirillum rubrum atcc 11170 at 1.90 a resolution 76 c2yw3E_ not modelled 92.5 14 PDB header:lyase Chain: E: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase/2-deydro-3- PDBTitle: crystal structure analysis of the 4-hydroxy-2-oxoglutarate aldolase/2-2 deydro-3-deoxyphosphogluconate aldolase from tthb1 77 d1ps9a1 not modelled 92.1 15 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 78 d1i60a_ not modelled 91.9 11 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:IolI-like 79 c2gq8A_ not modelled 91.9 20 PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase, fmn-binding; PDBTitle: structure of sye1, an oye homologue from s. ondeidensis, in complex2 with p-hydroxyacetophenone 80 d1uuma_ not modelled 91.8 18 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 81 c3aamA_ not modelled 91.8 20 PDB header:hydrolase Chain: A: PDB Molecule:endonuclease iv; PDBTitle: crystal structure of endonuclease iv from thermus thermophilus hb8 82 d1qf6a1 not modelled 91.8 18 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 83 d1bxba_ not modelled 91.6 17 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 84 c2ou4C_ not modelled 91.6 17 PDB header:isomerase Chain: C: PDB Molecule:d-tagatose 3-epimerase; PDBTitle: crystal structure of d-tagatose 3-epimerase from2 pseudomonas cichorii 85 d1icpa_ not modelled 91.6 20 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 86 c2ekcA_ not modelled 91.3 16 PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5 87 d1xm3a_ not modelled 91.0 17 Fold:TIM beta/alpha-barrel Superfamily:ThiG-like Family:ThiG-like 88 c2zdsB_ not modelled 90.8 13 PDB header:dna binding protein Chain: B: PDB Molecule:putative dna-binding protein; PDBTitle: crystal structure of sco6571 from streptomyces coelicolor2 a3(2) 89 c1djnB_ not modelled 90.7 19 PDB header:oxidoreductase Chain: B: PDB Molecule:trimethylamine dehydrogenase; PDBTitle: structural and biochemical characterization of recombinant wild type2 trimethylamine dehydrogenase from methylophilus methylotrophus (sp.3 w3a1) 90 d1wx0a1 not modelled 90.5 27 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 91 c3o63B_ not modelled 90.4 20 PDB header:transferase Chain: B: PDB Molecule:probable thiamine-phosphate pyrophosphorylase; PDBTitle: crystal structure of thiamin phosphate synthase from mycobacterium2 tuberculosis 92 d1gwja_ not modelled 90.4 15 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 93 c3khjE_ not modelled 90.3 15 PDB header:oxidoreductase Chain: E: PDB Molecule:inosine-5-monophosphate dehydrogenase; PDBTitle: c. parvum inosine monophosphate dehydrogenase bound by inhibitor c64 94 d1yx1a1 not modelled 90.2 18 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:KguE-like 95 d1k77a_ not modelled 89.8 13 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Hypothetical protein YgbM (EC1530) 96 d1vd6a1 not modelled 89.3 12 Fold:TIM beta/alpha-barrel Superfamily:PLC-like phosphodiesterases Family:Glycerophosphoryl diester phosphodiesterase 97 c3kwsB_ not modelled 89.2 23 PDB header:isomerase Chain: B: PDB Molecule:putative sugar isomerase; PDBTitle: crystal structure of putative sugar isomerase (yp_001305149.1) from2 parabacteroides distasonis atcc 8503 at 1.68 a resolution 98 c3s1vD_ not modelled 88.5 17 PDB header:transferase Chain: D: PDB Molecule:probable transaldolase; PDBTitle: transaldolase from thermoplasma acidophilum in complex with d-fructose2 6-phosphate schiff-base intermediate 99 c2ftpA_ not modelled 88.2 9 PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of hydroxymethylglutaryl-coa lyase from pseudomonas2 aeruginosa 100 c2i2xD_ not modelled 88.1 17 PDB header:transferase Chain: D: PDB Molecule:methyltransferase 1; PDBTitle: crystal structure of methanol:cobalamin methyltransferase complex2 mtabc from methanosarcina barkeri 101 d1xrsb1 not modelled 87.8 17 Fold:Flavodoxin-like Superfamily:Cobalamin (vitamin B12)-binding domain Family:Cobalamin (vitamin B12)-binding domain 102 d1un7a2 not modelled 87.8 25 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain 103 d1oyaa_ not modelled 87.8 18 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 104 d1zfja1 not modelled 87.8 16 Fold:TIM beta/alpha-barrel Superfamily:Inosine monophosphate dehydrogenase (IMPDH) Family:Inosine monophosphate dehydrogenase (IMPDH) 105 d2g0wa1 not modelled 87.7 15 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:IolI-like 106 c2x7vA_ not modelled 87.7 10 PDB header:hydrolase Chain: A: PDB Molecule:probable endonuclease 4; PDBTitle: crystal structure of thermotoga maritima endonuclease iv in2 the presence of zinc 107 c3k30B_ not modelled 87.6 18 PDB header:oxidoreductase Chain: B: PDB Molecule:histamine dehydrogenase; PDBTitle: histamine dehydrogenase from nocardiodes simplex 108 c3cqkB_ not modelled 87.5 16 PDB header:isomerase Chain: B: PDB Molecule:l-ribulose-5-phosphate 3-epimerase ulae; PDBTitle: crystal structure of l-xylulose-5-phosphate 3-epimerase ulae (form b)2 complex with zn2+ and sulfate 109 d1vjia_ not modelled 87.5 15 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 110 d1mxsa_ not modelled 87.5 16 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 111 d1d3ga_ not modelled 87.3 14 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 112 c2yciX_ not modelled 87.0 15 PDB header:transferase Chain: X: PDB Molecule:5-methyltetrahydrofolate corrinoid/iron sulfur protein PDBTitle: methyltransferase native 113 d1nyra1 not modelled 86.5 21 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 114 c2v5jB_ not modelled 86.5 19 PDB header:lyase Chain: B: PDB Molecule:2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; PDBTitle: apo class ii aldolase hpch 115 c3pajA_ not modelled 86.4 16 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase, carboxylating; PDBTitle: 2.00 angstrom resolution crystal structure of a quinolinate2 phosphoribosyltransferase from vibrio cholerae o1 biovar eltor str.3 n16961 116 c1qapA_ not modelled 86.2 13 PDB header:glycosyltransferase Chain: A: PDB Molecule:quinolinic acid phosphoribosyltransferase; PDBTitle: quinolinic acid phosphoribosyltransferase with bound2 quinolinic acid 117 d1qopa_ not modelled 86.2 18 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 118 d1hc7a1 not modelled 86.2 20 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 119 c2zvrA_ not modelled 85.9 13 PDB header:isomerase Chain: A: PDB Molecule:uncharacterized protein tm_0416; PDBTitle: crystal structure of a d-tagatose 3-epimerase-related2 protein from thermotoga maritima 120 c2kzhA_ not modelled 85.8 18 PDB header:isomerase Chain: A: PDB Molecule:tryptophan biosynthesis protein trpcf; PDBTitle: three-dimensional structure of a truncated phosphoribosylanthranilate2 isomerase (residues 255-384) from escherichia coli

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0