Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP09424
DateThu Jan 5 11:02:22 GMT 2012
Unique Job IDaebbcc3feeee975f

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3h2zA_
Top template information
PDB header:oxidoreductase
Chain: A: PDB Molecule:mannitol-1-phosphate 5-dehydrogenase;
PDBTitle: the crystal structure of mannitol-1-phosphate dehydrogenase from2 shigella flexneri
Confidence and coverage
Confidence:100.0% Coverage: 99%
377 residues ( 99% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MKALHFGAGNIGRGFIGKLLADAGIQLTFADVNQVVLDALNARHSYQVHVVGETEQVDTV
Secondary structure 
SS confidence 
Disorder  ??
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  SGVNAVSSIGDDVVDLIAQVDLVTTAVGPVVLERIAPAIAKGQVKRKEQGNESPLNIIAC
Secondary structure 
SS confidence 
Disorder 
??
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  ENMVRGTTQLKGHVMNALPEDAKAWVEEHVGFVDSAVDRIVPPSASATNDPLEVTVETFS
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  EWIVDKTQFKGALPNIPGMELTDNLMAFVERKLFTLNTGHAITAYLGKLAGHQTIRDAIL
Secondary structure 
SS confidence 
Disorder 
????
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  DEKIRAVVKGAMEESGAVLIKRYGFDADKHAAYIQKILGRFENPYLKDDVERVGRQPLRK
Secondary structure 
SS confidence 
Disorder 
?
??
???
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  LSAGDRLIKPLLGTLEYGLPHKNLIEGIAAAMHFRSEDDPQAQELAALIADKGPQAALAQ
Secondary structure 
SS confidence 
Disorder  ????
?
Disorder confidence 
 
   .........370.........380..
Sequence  ISGLDANSEVVSEAVTAYKAMQ
Secondary structure 
SS confidence 
Disorder 
???
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3h2z chain A

3D model

Region: 1 - 382
Aligned: 377
Modelled: 381
Confidence: 100.0%
Identity: 97%
PDB header:oxidoreductase
Chain: A: PDB Molecule:mannitol-1-phosphate 5-dehydrogenase;
PDBTitle: the crystal structure of mannitol-1-phosphate dehydrogenase from2 shigella flexneri

Phyre2

PDB 1m2w chain A

3D model

Region: 2 - 381
Aligned: 374
Modelled: 378
Confidence: 100.0%
Identity: 20%
PDB header:oxidoreductase
Chain: A: PDB Molecule:mannitol dehydrogenase;
PDBTitle: pseudomonas fluorescens mannitol 2-dehydrogenase ternary complex with2 nad and d-mannitol

Phyre2

PDB 1lj8 chain A domain 4

3D model

Region: 2 - 203
Aligned: 200
Modelled: 202
Confidence: 100.0%
Identity: 19%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: 6-phosphogluconate dehydrogenase-like, N-terminal domain

Phyre2

PDB 1lj8 chain A domain 3

3D model

Region: 204 - 381
Aligned: 173
Modelled: 176
Confidence: 100.0%
Identity: 24%
Fold: 6-phosphogluconate dehydrogenase C-terminal domain-like
Superfamily: 6-phosphogluconate dehydrogenase C-terminal domain-like
Family: Mannitol 2-dehydrogenase

Phyre2

PDB 3hn2 chain A

3D model

Region: 2 - 329
Aligned: 292
Modelled: 318
Confidence: 98.1%
Identity: 19%
PDB header:oxidoreductase
Chain: A: PDB Molecule:2-dehydropantoate 2-reductase;
PDBTitle: crystal structure of 2-dehydropantoate 2-reductase from geobacter2 metallireducens gs-15

Phyre2

PDB 2ew2 chain B

3D model

Region: 2 - 329
Aligned: 290
Modelled: 302
Confidence: 98.0%
Identity: 15%
PDB header:oxidoreductase
Chain: B: PDB Molecule:2-dehydropantoate 2-reductase, putative;
PDBTitle: crystal structure of the putative 2-dehydropantoate 2-reductase from2 enterococcus faecalis

Phyre2

PDB 3c7c chain B

3D model

Region: 1 - 124
Aligned: 124
Modelled: 124
Confidence: 97.9%
Identity: 16%
PDB header:oxidoreductase
Chain: B: PDB Molecule:octopine dehydrogenase;
PDBTitle: a structural basis for substrate and stereo selectivity in2 octopine dehydrogenase (odh-nadh-l-arginine)

Phyre2

PDB 3ghy chain A

3D model

Region: 1 - 329
Aligned: 287
Modelled: 301
Confidence: 97.6%
Identity: 19%
PDB header:oxidoreductase
Chain: A: PDB Molecule:ketopantoate reductase protein;
PDBTitle: crystal structure of a putative ketopantoate reductase from ralstonia2 solanacearum molk2

Phyre2

PDB 3ego chain B

3D model

Region: 1 - 331
Aligned: 279
Modelled: 312
Confidence: 97.5%
Identity: 16%
PDB header:oxidoreductase
Chain: B: PDB Molecule:probable 2-dehydropantoate 2-reductase;
PDBTitle: crystal structure of probable 2-dehydropantoate 2-reductase2 pane from bacillus subtilis

Phyre2

PDB 3hwr chain A

3D model

Region: 1 - 329
Aligned: 283
Modelled: 292
Confidence: 97.3%
Identity: 16%
PDB header:oxidoreductase
Chain: A: PDB Molecule:2-dehydropantoate 2-reductase;
PDBTitle: crystal structure of pane/apba family ketopantoate reductase2 (yp_299159.1) from ralstonia eutropha jmp134 at 2.15 a resolution

Phyre2

PDB 3k96 chain B

3D model

Region: 2 - 270
Aligned: 231
Modelled: 269
Confidence: 97.1%
Identity: 13%
PDB header:oxidoreductase
Chain: B: PDB Molecule:glycerol-3-phosphate dehydrogenase [nad(p)+];
PDBTitle: 2.1 angstrom resolution crystal structure of glycerol-3-phosphate2 dehydrogenase (gpsa) from coxiella burnetii

Phyre2

PDB 1bg6 chain A

3D model

Region: 2 - 136
Aligned: 119
Modelled: 135
Confidence: 97.1%
Identity: 17%
PDB header:oxidoreductase
Chain: A: PDB Molecule:n-(1-d-carboxylethyl)-l-norvaline dehydrogenase;
PDBTitle: crystal structure of the n-(1-d-carboxylethyl)-l-norvaline2 dehydrogenase from arthrobacter sp. strain 1c

Phyre2

PDB 2axq chain A

3D model

Region: 2 - 120
Aligned: 105
Modelled: 105
Confidence: 97.1%
Identity: 14%
PDB header:oxidoreductase
Chain: A: PDB Molecule:saccharopine dehydrogenase;
PDBTitle: apo histidine-tagged saccharopine dehydrogenase (l-glu2 forming) from saccharomyces cerevisiae

Phyre2

PDB 1mv8 chain A domain 2

3D model

Region: 1 - 136
Aligned: 133
Modelled: 136
Confidence: 97.1%
Identity: 14%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: 6-phosphogluconate dehydrogenase-like, N-terminal domain

Phyre2

PDB 2qyt chain A

3D model

Region: 1 - 257
Aligned: 214
Modelled: 229
Confidence: 97.0%
Identity: 19%
PDB header:oxidoreductase
Chain: A: PDB Molecule:2-dehydropantoate 2-reductase;
PDBTitle: crystal structure of 2-dehydropantoate 2-reductase from porphyromonas2 gingivalis w83

Phyre2

PDB 3g17 chain H

3D model

Region: 1 - 331
Aligned: 274
Modelled: 291
Confidence: 96.8%
Identity: 15%
PDB header:structural genomics, unknown function
Chain: H: PDB Molecule:similar to 2-dehydropantoate 2-reductase;
PDBTitle: structure of putative 2-dehydropantoate 2-reductase from2 staphylococcus aureus

Phyre2

PDB 1n1e chain A domain 2

3D model

Region: 1 - 127
Aligned: 115
Modelled: 127
Confidence: 96.8%
Identity: 13%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: 6-phosphogluconate dehydrogenase-like, N-terminal domain

Phyre2

PDB 1txg chain A domain 2

3D model

Region: 1 - 122
Aligned: 105
Modelled: 122
Confidence: 96.6%
Identity: 12%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: 6-phosphogluconate dehydrogenase-like, N-terminal domain

Phyre2

PDB 3qha chain B

3D model

Region: 1 - 134
Aligned: 104
Modelled: 105
Confidence: 96.6%
Identity: 17%
PDB header:oxidoreductase
Chain: B: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of a putative oxidoreductase from mycobacterium2 avium 104

Phyre2

PDB 1txg chain A

3D model

Region: 1 - 126
Aligned: 107
Modelled: 116
Confidence: 96.6%
Identity: 14%
PDB header:oxidoreductase
Chain: A: PDB Molecule:glycerol-3-phosphate dehydrogenase [nad(p)+];
PDBTitle: structure of glycerol-3-phosphate dehydrogenase from archaeoglobus2 fulgidus

Phyre2
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c3h2zA_
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c1m2wA_
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d1lj8a4
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d1lj8a3
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c3hn2A_
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c2ew2B_
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c3c7cB_
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c3ghyA_
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c3egoB_
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c3hwrA_
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c3k96B_
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c1bg6A_
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c2axqA_
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d1mv8a2
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c2qytA_
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c3g17H_
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d1n1ea2
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d1txga2
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c3qhaB_
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c1txgA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3h2zA_
100.0 97 PDB header:oxidoreductase
Chain: A: PDB Molecule:mannitol-1-phosphate 5-dehydrogenase;
PDBTitle: the crystal structure of mannitol-1-phosphate dehydrogenase from2 shigella flexneri
2c1m2wA_
100.0 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:mannitol dehydrogenase;
PDBTitle: pseudomonas fluorescens mannitol 2-dehydrogenase ternary complex with2 nad and d-mannitol
3d1lj8a4
100.0 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
4d1lj8a3
100.0 24 Fold:6-phosphogluconate dehydrogenase C-terminal domain-like
Superfamily:6-phosphogluconate dehydrogenase C-terminal domain-like
Family:Mannitol 2-dehydrogenase
5c3hn2A_
98.1 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-dehydropantoate 2-reductase;
PDBTitle: crystal structure of 2-dehydropantoate 2-reductase from geobacter2 metallireducens gs-15
6c2ew2B_
98.0 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:2-dehydropantoate 2-reductase, putative;
PDBTitle: crystal structure of the putative 2-dehydropantoate 2-reductase from2 enterococcus faecalis
7c3c7cB_
97.9 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:octopine dehydrogenase;
PDBTitle: a structural basis for substrate and stereo selectivity in2 octopine dehydrogenase (odh-nadh-l-arginine)
8c3ghyA_
97.6 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:ketopantoate reductase protein;
PDBTitle: crystal structure of a putative ketopantoate reductase from ralstonia2 solanacearum molk2
9c3egoB_
97.5 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:probable 2-dehydropantoate 2-reductase;
PDBTitle: crystal structure of probable 2-dehydropantoate 2-reductase2 pane from bacillus subtilis
10c3hwrA_
97.3 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-dehydropantoate 2-reductase;
PDBTitle: crystal structure of pane/apba family ketopantoate reductase2 (yp_299159.1) from ralstonia eutropha jmp134 at 2.15 a resolution
11c3k96B_
97.1 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:glycerol-3-phosphate dehydrogenase [nad(p)+];
PDBTitle: 2.1 angstrom resolution crystal structure of glycerol-3-phosphate2 dehydrogenase (gpsa) from coxiella burnetii
12c1bg6A_
97.1 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:n-(1-d-carboxylethyl)-l-norvaline dehydrogenase;
PDBTitle: crystal structure of the n-(1-d-carboxylethyl)-l-norvaline2 dehydrogenase from arthrobacter sp. strain 1c
13c2axqA_
97.1 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:saccharopine dehydrogenase;
PDBTitle: apo histidine-tagged saccharopine dehydrogenase (l-glu2 forming) from saccharomyces cerevisiae
14d1mv8a2
97.1 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
15c2qytA_
97.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-dehydropantoate 2-reductase;
PDBTitle: crystal structure of 2-dehydropantoate 2-reductase from porphyromonas2 gingivalis w83
16c3g17H_
96.8 15 PDB header:structural genomics, unknown function
Chain: H: PDB Molecule:similar to 2-dehydropantoate 2-reductase;
PDBTitle: structure of putative 2-dehydropantoate 2-reductase from2 staphylococcus aureus
17d1n1ea2
96.8 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
18d1txga2
96.6 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
19c3qhaB_
96.6 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of a putative oxidoreductase from mycobacterium2 avium 104
20c1txgA_
96.6 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:glycerol-3-phosphate dehydrogenase [nad(p)+];
PDBTitle: structure of glycerol-3-phosphate dehydrogenase from archaeoglobus2 fulgidus
21c1m67A_
not modelled 96.5 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:glycerol-3-phosphate dehydrogenase;
PDBTitle: crystal structure of leishmania mexicana gpdh complexed with inhibitor2 2-bromo-6-hydroxy-purine
22c2ofpB_
not modelled 96.4 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:ketopantoate reductase;
PDBTitle: crystal structure of escherichia coli ketopantoate2 reductase in a ternary complex with nadp+ and pantoate
23c3ic5A_
not modelled 96.3 23 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative saccharopine dehydrogenase;
PDBTitle: n-terminal domain of putative saccharopine dehydrogenase from ruegeria2 pomeroyi.
24d1bg6a2
not modelled 96.1 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
25c3i83B_
not modelled 96.0 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:2-dehydropantoate 2-reductase;
PDBTitle: crystal structure of 2-dehydropantoate 2-reductase from methylococcus2 capsulatus
26c2f1kD_
not modelled 95.8 16 PDB header:oxidoreductase
Chain: D: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of synechocystis arogenate dehydrogenase
27c3l4bG_
not modelled 95.5 5 PDB header:transport protein
Chain: G: PDB Molecule:trka k+ channel protien tm1088b;
PDBTitle: crystal structure of an octomeric two-subunit trka k+ channel ring2 gating assembly, tm1088a:tm1088b, from thermotoga maritima
28c2z2vA_
not modelled 95.4 31 PDB header:oxidoreductase
Chain: A: PDB Molecule:hypothetical protein ph1688;
PDBTitle: crystal structure of l-lysine dehydrogenase from2 hyperthermophilic archaeon pyrococcus horikoshii
29c2gf2B_
not modelled 95.4 25 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-hydroxyisobutyrate dehydrogenase;
PDBTitle: crystal structure of human hydroxyisobutyrate dehydrogenase
30d2f1ka2
not modelled 95.3 26 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
31c3d4oA_
not modelled 95.3 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:dipicolinate synthase subunit a;
PDBTitle: crystal structure of dipicolinate synthase subunit a (np_243269.1)2 from bacillus halodurans at 2.10 a resolution
32d1jaya_
not modelled 95.1 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
33c3l6dB_
not modelled 95.1 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of putative oxidoreductase from pseudomonas putida2 kt2440
34c1e5lA_
not modelled 94.7 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:saccharopine reductase;
PDBTitle: apo saccharopine reductase from magnaporthe grisea
35c2ep9A_
not modelled 94.7 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:l-gulonate 3-dehydrogenase;
PDBTitle: crystal structure of the rabbit l-gulonate 3-dehydrogenase2 (nadh form)
36c3dojA_
not modelled 94.6 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:dehydrogenase-like protein;
PDBTitle: structure of glyoxylate reductase 1 from arabidopsis2 (atglyr1)
37d1ks9a2
not modelled 94.5 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
38d1lssa_
not modelled 94.4 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Potassium channel NAD-binding domain
39d2ahra2
not modelled 94.3 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
40c3ckyA_
not modelled 94.1 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-hydroxymethyl glutarate dehydrogenase;
PDBTitle: structural and kinetic properties of a beta-hydroxyacid dehydrogenase2 involved in nicotinate fermentation
41c3eywA_
not modelled 94.1 18 PDB header:transport protein
Chain: A: PDB Molecule:c-terminal domain of glutathione-regulated potassium-efflux
PDBTitle: crystal structure of the c-terminal domain of e. coli kefc in complex2 with keff
42c3c24A_
not modelled 94.0 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of a putative oxidoreductase (yp_511008.1) from2 jannaschia sp. ccs1 at 1.62 a resolution
43c3g0oA_
not modelled 93.9 28 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-hydroxyisobutyrate dehydrogenase;
PDBTitle: crystal structure of 3-hydroxyisobutyrate dehydrogenase2 (ygbj) from salmonella typhimurium
44d1dlja2
not modelled 93.9 30 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
45c1z82A_
not modelled 93.8 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:glycerol-3-phosphate dehydrogenase;
PDBTitle: crystal structure of glycerol-3-phosphate dehydrogenase (tm0378) from2 thermotoga maritima at 2.00 a resolution
46c2uyyD_
not modelled 93.3 23 PDB header:cytokine
Chain: D: PDB Molecule:n-pac protein;
PDBTitle: structure of the cytokine-like nuclear factor n-pac
47c2vhyB_
not modelled 93.3 24 PDB header:oxidoreductase
Chain: B: PDB Molecule:alanine dehydrogenase;
PDBTitle: crystal structure of apo l-alanine dehydrogenase from2 mycobacterium tuberculosis
48c3gg2B_
not modelled 92.9 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:sugar dehydrogenase, udp-glucose/gdp-mannose
PDBTitle: crystal structure of udp-glucose 6-dehydrogenase from2 porphyromonas gingivalis bound to product udp-glucuronate
49c2vrcD_
not modelled 92.7 17 PDB header:oxidoreductase
Chain: D: PDB Molecule:triphenylmethane reductase;
PDBTitle: crystal structure of the citrobacter sp. triphenylmethane2 reductase complexed with nadp(h)
50c1pjcA_
not modelled 92.5 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:protein (l-alanine dehydrogenase);
PDBTitle: l-alanine dehydrogenase complexed with nad
51c1gpjA_
not modelled 92.5 23 PDB header:reductase
Chain: A: PDB Molecule:glutamyl-trna reductase;
PDBTitle: glutamyl-trna reductase from methanopyrus kandleri
52c2y0dB_
not modelled 92.3 33 PDB header:oxidoreductase
Chain: B: PDB Molecule:udp-glucose dehydrogenase;
PDBTitle: bcec mutation y10k
53d2hmva1
not modelled 92.3 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Potassium channel NAD-binding domain
54d1l7da1
not modelled 92.1 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
55c1vpdA_
not modelled 92.0 26 PDB header:oxidoreductase
Chain: A: PDB Molecule:tartronate semialdehyde reductase;
PDBTitle: x-ray crystal structure of tartronate semialdehyde reductase2 [salmonella typhimurium lt2]
56c3ktdC_
not modelled 91.5 17 PDB header:oxidoreductase
Chain: C: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of a putative prephenate dehydrogenase (cgl0226)2 from corynebacterium glutamicum atcc 13032 at 2.60 a resolution
57c3dttA_
not modelled 91.5 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadp oxidoreductase;
PDBTitle: crystal structure of a putative f420 dependent nadp-reductase2 (arth_0613) from arthrobacter sp. fb24 at 1.70 a resolution
58d1pgja2
not modelled 91.3 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
59c2ahrB_
not modelled 91.1 23 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative pyrroline carboxylate reductase;
PDBTitle: crystal structures of 1-pyrroline-5-carboxylate reductase from human2 pathogen streptococcus pyogenes
60c3prjB_
not modelled 91.0 21 PDB header:oxidoreductase
Chain: B: PDB Molecule:udp-glucose 6-dehydrogenase;
PDBTitle: role of packing defects in the evolution of allostery and induced fit2 in human udp-glucose dehydrogenase.
61c3cumA_
not modelled 90.9 30 PDB header:oxidoreductase
Chain: A: PDB Molecule:probable 3-hydroxyisobutyrate dehydrogenase;
PDBTitle: crystal structure of a possible 3-hydroxyisobutyrate dehydrogenase2 from pseudomonas aeruginosa pao1
62c1mv8A_
not modelled 90.7 27 PDB header:oxidoreductase
Chain: A: PDB Molecule:gdp-mannose 6-dehydrogenase;
PDBTitle: 1.55 a crystal structure of a ternary complex of gdp-mannose2 dehydrogenase from psuedomonas aeruginosa
63c3plnA_
not modelled 90.2 30 PDB header:oxidoreductase
Chain: A: PDB Molecule:udp-glucose 6-dehydrogenase;
PDBTitle: crystal structure of klebsiella pneumoniae udp-glucose 6-dehydrogenase2 complexed with udp-glucose
64c3euwB_
not modelled 90.2 26 PDB header:oxidoreductase
Chain: B: PDB Molecule:myo-inositol dehydrogenase;
PDBTitle: crystal structure of a myo-inositol dehydrogenase from corynebacterium2 glutamicum atcc 13032
65d1obba1
not modelled 90.1 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
66c3b1fA_
not modelled 90.1 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from streptococcus2 mutans
67c1i36A_
not modelled 89.9 18 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:conserved hypothetical protein mth1747;
PDBTitle: structure of conserved protein mth1747 of unknown function2 reveals structural similarity with 3-hydroxyacid3 dehydrogenases
68d1uxja1
not modelled 89.8 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
69c3ezyB_
not modelled 89.6 21 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:dehydrogenase;
PDBTitle: crystal structure of probable dehydrogenase tm_0414 from2 thermotoga maritima
70c2w2kB_
not modelled 89.5 33 PDB header:oxidoreductase
Chain: B: PDB Molecule:d-mandelate dehydrogenase;
PDBTitle: crystal structure of the apo forms of rhodotorula graminis2 d-mandelate dehydrogenase at 1.8a.
71c1ks9A_
not modelled 88.9 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-dehydropantoate 2-reductase;
PDBTitle: ketopantoate reductase from escherichia coli
72c2rirA_
not modelled 88.8 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:dipicolinate synthase, a chain;
PDBTitle: crystal structure of dipicolinate synthase, a chain, from bacillus2 subtilis
73d1i36a2
not modelled 88.8 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
74c2izzE_
not modelled 88.7 16 PDB header:oxidoreductase
Chain: E: PDB Molecule:pyrroline-5-carboxylate reductase 1;
PDBTitle: crystal structure of human pyrroline-5-carboxylate2 reductase
75d1pjca1
not modelled 88.7 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
76d1yqga2
not modelled 88.4 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
77c2x4gA_
not modelled 88.3 23 PDB header:isomerase
Chain: A: PDB Molecule:nucleoside-diphosphate-sugar epimerase;
PDBTitle: crystal structure of pa4631, a nucleoside-diphosphate-sugar2 epimerase from pseudomonas aeruginosa
78c2g5cD_
not modelled 88.3 20 PDB header:oxidoreductase
Chain: D: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from aquifex aeolicus
79c2vq3B_
not modelled 88.1 19 PDB header:oxidoreductase
Chain: B: PDB Molecule:metalloreductase steap3;
PDBTitle: crystal structure of the membrane proximal oxidoreductase2 domain of human steap3, the dominant ferric reductase of3 the erythroid transferrin cycle
80c3llvA_
not modelled 88.0 21 PDB header:nad(p) binding protein
Chain: A: PDB Molecule:exopolyphosphatase-related protein;
PDBTitle: the crystal structure of the nad(p)-binding domain of an2 exopolyphosphatase-related protein from archaeoglobus fulgidus to3 1.7a
81c1dliA_
not modelled 88.0 30 PDB header:oxidoreductase
Chain: A: PDB Molecule:udp-glucose dehydrogenase;
PDBTitle: the first structure of udp-glucose dehydrogenase (udpgdh) reveals the2 catalytic residues necessary for the two-fold oxidation
82d1gpja2
not modelled 88.0 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
83c2eezG_
not modelled 87.9 25 PDB header:oxidoreductase
Chain: G: PDB Molecule:alanine dehydrogenase;
PDBTitle: crystal structure of alanine dehydrogenase from themus thermophilus
84c3iusB_
not modelled 87.6 24 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized conserved protein;
PDBTitle: the structure of a functionally unknown conserved protein2 from silicibacter pomeroyi dss
85c2o3jC_
not modelled 87.6 14 PDB header:oxidoreductase
Chain: C: PDB Molecule:udp-glucose 6-dehydrogenase;
PDBTitle: structure of caenorhabditis elegans udp-glucose dehydrogenase
86c3pefA_
not modelled 87.4 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:6-phosphogluconate dehydrogenase, nad-binding;
PDBTitle: crystal structure of gamma-hydroxybutyrate dehydrogenase from2 geobacter metallireducens in complex with nadp+
87c3icpA_
not modelled 87.3 30 PDB header:isomerase
Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: crystal structure of udp-galactose 4-epimerase
88c1obbB_
not modelled 87.1 23 PDB header:hydrolase
Chain: B: PDB Molecule:alpha-glucosidase;
PDBTitle: alpha-glucosidase a, agla, from thermotoga maritima in2 complex with maltose and nad+
89c3ceaA_
not modelled 87.1 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:myo-inositol 2-dehydrogenase;
PDBTitle: crystal structure of myo-inositol 2-dehydrogenase (np_786804.1) from2 lactobacillus plantarum at 2.40 a resolution
90d1vl0a_
not modelled 86.9 30 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
91c3h2sA_
not modelled 86.3 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative nadh-flavin reductase;
PDBTitle: crystal structure of the q03b84 protein from lactobacillus2 casei. northeast structural genomics consortium target3 lcr19.
92c3qvoA_
not modelled 86.3 16 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:nmra family protein;
PDBTitle: structure of a rossmann-fold nad(p)-binding family protein from2 shigella flexneri.
93c3gpiA_
not modelled 86.3 27 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: structure of putative nad-dependent epimerase/dehydratase2 from methylobacillus flagellatus
94c3dhnA_
not modelled 85.8 27 PDB header:isomerase, lyase
Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: crystal structure of the putative epimerase q89z24_bactn2 from bacteroides thetaiotaomicron. northeast structural3 genomics consortium target btr310.
95c3d1lB_
not modelled 85.6 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative nadp oxidoreductase bf3122;
PDBTitle: crystal structure of putative nadp oxidoreductase bf3122 from2 bacteroides fragilis
96c3c85A_
not modelled 85.3 19 PDB header:transport protein
Chain: A: PDB Molecule:putative glutathione-regulated potassium-efflux system
PDBTitle: crystal structure of trka domain of putative glutathione-regulated2 potassium-efflux kefb from vibrio parahaemolyticus
97d1wdka3
not modelled 85.1 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
98c3nt5B_
not modelled 85.0 23 PDB header:oxidoreductase
Chain: B: PDB Molecule:inositol 2-dehydrogenase/d-chiro-inositol 3-dehydrogenase;
PDBTitle: crystal structure of myo-inositol dehydrogenase from bacillus subtilis2 with bound cofactor and product inosose
99c2graA_
not modelled 85.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:pyrroline-5-carboxylate reductase 1;
PDBTitle: crystal structure of human pyrroline-5-carboxylate reductase complexed2 with nadp
100c3dzbA_
not modelled 84.8 17 PDB header:biosynthetic protein
Chain: A: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from streptococcus2 thermophilus
101c2pv7B_
not modelled 84.4 23 PDB header:isomerase, oxidoreductase
Chain: B: PDB Molecule:t-protein [includes: chorismate mutase (ec 5.4.99.5) (cm)
PDBTitle: crystal structure of chorismate mutase / prephenate dehydrogenase2 (tyra) (1574749) from haemophilus influenzae rd at 2.00 a resolution
102c3e8xA_
not modelled 84.3 22 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative nad-dependent epimerase/dehydratase;
PDBTitle: putative nad-dependent epimerase/dehydratase from bacillus halodurans.
103c2ggsB_
not modelled 84.0 21 PDB header:oxidoreductase
Chain: B: PDB Molecule:273aa long hypothetical dtdp-4-dehydrorhamnose
PDBTitle: crystal structure of hypothetical dtdp-4-dehydrorhamnose2 reductase from sulfolobus tokodaii
104d1s6ya1
not modelled 84.0 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
105d1e5qa1
not modelled 83.9 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
106c3n7uD_
not modelled 83.2 31 PDB header:oxidoreductase
Chain: D: PDB Molecule:formate dehydrogenase;
PDBTitle: nad-dependent formate dehydrogenase from higher-plant arabidopsis2 thaliana in complex with nad and azide
107c2glxD_
not modelled 83.2 14 PDB header:oxidoreductase
Chain: D: PDB Molecule:1,5-anhydro-d-fructose reductase;
PDBTitle: crystal structure analysis of bacterial 1,5-af reductase
108c3e18A_
not modelled 82.9 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase;
PDBTitle: crystal structure of nad-binding protein from listeria innocua
109c1yj8C_
not modelled 82.9 20 PDB header:oxidoreductase
Chain: C: PDB Molecule:glycerol-3-phosphate dehydrogenase;
PDBTitle: initial structural analysis of plasmodium falciparum glycerol-3-2 phosphate dehydrogenase
110c1xeaD_
not modelled 82.9 28 PDB header:oxidoreductase
Chain: D: PDB Molecule:oxidoreductase, gfo/idh/moca family;
PDBTitle: crystal structure of a gfo/idh/moca family oxidoreductase2 from vibrio cholerae
111c2q3eH_
not modelled 82.8 32 PDB header:oxidoreductase
Chain: H: PDB Molecule:udp-glucose 6-dehydrogenase;
PDBTitle: structure of human udp-glucose dehydrogenase complexed with nadh and2 udp-glucose
112d1ojua1
not modelled 82.5 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
113c2ho3D_
not modelled 82.1 21 PDB header:oxidoreductase
Chain: D: PDB Molecule:oxidoreductase, gfo/idh/moca family;
PDBTitle: crystal structure of oxidoreductase, gfo/idh/moca family from2 streptococcus pneumoniae
114c3gvpB_
not modelled 81.9 19 PDB header:hydrolase
Chain: B: PDB Molecule:adenosylhomocysteinase 3;
PDBTitle: human sahh-like domain of human adenosylhomocysteinase 3
115c3e9mC_
not modelled 81.9 12 PDB header:oxidoreductase
Chain: C: PDB Molecule:oxidoreductase, gfo/idh/moca family;
PDBTitle: crystal structure of an oxidoreductase from enterococcus2 faecalis
116c1vkzA_
not modelled 81.8 31 PDB header:ligase
Chain: A: PDB Molecule:phosphoribosylamine--glycine ligase;
PDBTitle: crystal structure of phosphoribosylamine--glycine ligase (tm1250) from2 thermotoga maritima at 2.30 a resolution
117c2q4eB_
not modelled 81.5 12 PDB header:oxidoreductase
Chain: B: PDB Molecule:probable oxidoreductase at4g09670;
PDBTitle: ensemble refinement of the protein crystal structure of gene product2 from arabidopsis thaliana at4g09670
118c3dhyC_
not modelled 81.3 31 PDB header:hydrolase
Chain: C: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structures of mycobacterium tuberculosis s-adenosyl-l-2 homocysteine hydrolase in ternary complex with substrate and3 inhibitors
119c2dt5A_
not modelled 80.9 21 PDB header:dna binding protein
Chain: A: PDB Molecule:at-rich dna-binding protein;
PDBTitle: crystal structure of ttha1657 (at-rich dna-binding protein) from2 thermus thermophilus hb8
120c1d4fD_
not modelled 80.7 18 PDB header:hydrolase
Chain: D: PDB Molecule:s-adenosylhomocysteine hydrolase;
PDBTitle: crystal structure of recombinant rat-liver d244e mutant s-2 adenosylhomocysteine hydrolase

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0