Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	N	I	Q	A	L	L	S	E	K	V	R	Q	A	M	I	A	A	G	A	P	A	D	C	E	P	Q	V	R	Q	S	A	K	V	Q	F	G	D	Y	Q	A	N	G	M	M	A	V	A	K	K	L	G	M	A	P	R	Q	L	A	E
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Q	V	L	T	H	L	D	L	N	G	I	A	S	K	V	E	I	A	G	P	G	F	I	N	I	F	L	D	P	A	F	L	A	E	H	V	Q	Q	A	L	A	S	D	R	L	G	V	A	T	P	E	K	Q	T	I	V	V	D	Y	S
Secondary structure
SS confidence
Disorder																																											?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	P	N	V	A	K	E	M	H	V	G	H	L	R	S	T	I	I	G	D	A	A	V	R	T	L	E	F	L	G	H	K	V	I	R	A	N	H	V	G	D	W	G	T	Q	F	G	M	L	I	A	W	L	E	K	Q	Q	Q	E	N
Secondary structure
SS confidence
Disorder																																																									?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	G	E	M	E	L	A	D	L	E	G	F	Y	R	D	A	K	K	H	Y	D	E	D	E	E	F	A	E	R	A	R	N	Y	V	V	K	L	Q	S	G	D	E	Y	F	R	E	M	W	R	K	L	V	D	I	T	M	T	Q	N	Q
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		I	T	Y	D	R	L	N	V	T	L	T	R	D	D	V	M	G	E	S	L	Y	N	P	M	L	P	G	I	V	A	D	L	K	A	K	G	L	A	V	E	S	E	G	A	T	V	V	F	L	D	E	F	K	N	K	E	G	E	P	M
Secondary structure
SS confidence
Disorder																																					?															?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		G	V	I	I	Q	K	K	D	G	G	Y	L	Y	T	T	T	D	I	A	C	A	K	Y	R	Y	E	T	L	H	A	D	R	V	L	Y	Y	I	D	S	R	Q	H	Q	H	L	M	Q	A	W	A	I	V	R	K	A	G	Y	V	P	E
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		S	V	P	L	E	H	H	M	F	G	M	M	L	G	K	D	G	K	P	F	K	T	R	A	G	G	T	V	K	L	A	D	L	L	D	E	A	L	E	R	A	R	R	L	V	A	E	K	N	P	D	M	P	A	D	E	L	E	K	L
Secondary structure
SS confidence
Disorder																?	?	?	?	?	?																										?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		A	N	A	V	G	I	G	A	V	K	Y	A	D	L	S	K	N	R	T	T	D	Y	I	F	D	W	D	N	M	L	A	F	E	G	N	T	A	P	Y	M	Q	Y	A	Y	T	R	V	L	S	V	F	R	K	A	E	I	D	E	E	Q
Secondary structure
SS confidence
Disorder																																?				?																				?	?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		L	A	A	A	P	V	I	I	R	E	D	R	E	A	Q	L	A	A	R	L	L	Q	F	E	E	T	L	T	V	V	A	R	E	G	T	P	H	V	M	C	A	Y	L	Y	D	L	A	G	L	F	S	G	F	Y	E	H	C	P	I	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.
Sequence		S	A	E	N	E	E	V	R	N	S	R	L	K	L	A	Q	L	T	A	K	T	L	K	L	G	L	D	T	L	G	I	E	T	V	E	R	M
Secondary structure
SS confidence
Disorder					?																												?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1f7u chain A Region: 1 - 577 Aligned: 561 Modelled: 577 Confidence: 100.0% Identity: 32% PDB header:ligase/rna Chain: A: PDB Molecule:arginyl-trna synthetase; PDBTitle: crystal structure of the arginyl-trna synthetase complexed with the2 trna(arg) and l-arg Phyre2 PDB 2zuf chain A Region: 1 - 577 Aligned: 569 Modelled: 577 Confidence: 100.0% Identity: 28% PDB header:ligase/rna Chain: A: PDB Molecule:arginyl-trna synthetase; PDBTitle: crystal structure of pyrococcus horikoshii arginyl-trna2 synthetase complexed with trna(arg) Phyre2 PDB 1iq0 chain A Region: 3 - 577 Aligned: 548 Modelled: 573 Confidence: 100.0% Identity: 28% PDB header:ligase Chain: A: PDB Molecule:arginyl-trna synthetase; PDBTitle: thermus thermophilus arginyl-trna synthetase Phyre2 PDB 3fnr chain A Region: 87 - 577 Aligned: 444 Modelled: 464 Confidence: 100.0% Identity: 24% PDB header:transferase Chain: A: PDB Molecule:arginyl-trna synthetase; PDBTitle: crystal structure of putative arginyl t-rna synthetase from2 campylobacter jejuni; Phyre2 PDB 1f7u chain A domain 2 Region: 107 - 454 Aligned: 338 Modelled: 348 Confidence: 100.0% Identity: 33% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain Phyre2 PDB 1iq0 chain A domain 2 Region: 109 - 453 Aligned: 330 Modelled: 345 Confidence: 100.0% Identity: 25% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain Phyre2 PDB 2x1l chain C Region: 113 - 569 Aligned: 371 Modelled: 379 Confidence: 100.0% Identity: 18% PDB header:ligase Chain: C: PDB Molecule:methionyl-trna synthetase; PDBTitle: crystal structure of mycobacterium smegmatis methionyl-trna2 synthetase in complex with methionine and adenosine Phyre2 PDB 2ct8 chain A Region: 113 - 569 Aligned: 362 Modelled: 379 Confidence: 100.0% Identity: 18% PDB header:ligase/rna Chain: A: PDB Molecule:methionyl-trna synthetase; PDBTitle: crystal structure of aquifex aeolicus methionyl-trna2 synthetase complexed with trna(met) and methionyl-adenylate3 anologue Phyre2 PDB 1woy chain A Region: 112 - 566 Aligned: 365 Modelled: 377 Confidence: 100.0% Identity: 18% PDB header:ligase Chain: A: PDB Molecule:methionyl-trna synthetase; PDBTitle: crystal structure of methionyl trna synthetase y225f mutant2 from thermus thermophilus Phyre2 PDB 3tqo chain A Region: 109 - 576 Aligned: 339 Modelled: 364 Confidence: 100.0% Identity: 19% PDB header:ligase Chain: A: PDB Molecule:cysteinyl-trna synthetase; PDBTitle: structure of the cysteinyl-trna synthetase (cyss) from coxiella2 burnetii. Phyre2 PDB 1pfu chain A Region: 113 - 569 Aligned: 368 Modelled: 371 Confidence: 100.0% Identity: 15% PDB header:ligase Chain: A: PDB Molecule:methionyl-trna synthetase; PDBTitle: methionyl-trna synthetase from escherichia coli complexed2 with methionine phosphinate Phyre2 PDB 3kfl chain A Region: 111 - 569 Aligned: 373 Modelled: 378 Confidence: 100.0% Identity: 20% PDB header:ligase Chain: A: PDB Molecule:methionyl-trna synthetase; PDBTitle: leishmania major methionyl-trna synthetase in complex with2 methionyladenylate and pyrophosphate Phyre2 PDB 1rqg chain A Region: 113 - 574 Aligned: 379 Modelled: 384 Confidence: 100.0% Identity: 18% PDB header:ligase Chain: A: PDB Molecule:methionyl-trna synthetase; PDBTitle: methionyl-trna synthetase from pyrococcus abyssi Phyre2 PDB 1u0b chain B Region: 107 - 571 Aligned: 341 Modelled: 349 Confidence: 100.0% Identity: 17% PDB header:ligase/rna Chain: B: PDB Molecule:cysteinyl trna; PDBTitle: crystal structure of cysteinyl-trna synthetase binary2 complex with trnacys Phyre2 PDB 1li5 chain A domain 2 Region: 109 - 454 Aligned: 261 Modelled: 268 Confidence: 100.0% Identity: 18% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain Phyre2 PDB 1pfv chain A domain 2 Region: 113 - 457 Aligned: 264 Modelled: 264 Confidence: 100.0% Identity: 16% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain Phyre2 PDB 2d5b chain A domain 2 Region: 112 - 455 Aligned: 262 Modelled: 266 Confidence: 100.0% Identity: 18% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain Phyre2 PDB 1ivs chain A domain 4 Region: 87 - 454 Aligned: 304 Modelled: 306 Confidence: 100.0% Identity: 16% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain Phyre2 PDB 1rqg chain A domain 2 Region: 113 - 457 Aligned: 264 Modelled: 267 Confidence: 100.0% Identity: 23% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain Phyre2 PDB 3sp1 chain B Region: 112 - 536 Aligned: 317 Modelled: 339 Confidence: 100.0% Identity: 20% PDB header:ligase Chain: B: PDB Molecule:cysteinyl-trna synthetase; PDBTitle: crystal structure of cysteinyl-trna synthetase (cyss) from borrelia2 burgdorferi Phyre2 1 c1f7uA_ 2 c2zufA_ 3 c1iq0A_ 4 c3fnrA_ 5 d1f7ua2 6 d1iq0a2 7 c2x1lC_ 8 c2ct8A_ 9 c1woyA_ 10 c3tqoA_ 11 c1pfuA_ 12 c3kflA_ 13 c1rqgA_ 14 c1u0bB_ 15 d1li5a2 16 d1pfva2 17 d2d5ba2 18 d1ivsa4 19 d1rqga2 20 c3sp1B_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134