Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	V	A	M	D	N	A	I	L	E	N	I	L	R	Q	V	R	P	L	I	G	Q	G	K	V	A	D	Y	I	P	A	L	A	T	V	D	G	S	R	L	G	I	A	I	C	T	V	D	G	Q	L	F	Q	A	G	D	A	Q	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																?	?															?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	F	S	I	Q	S	I	S	K	V	L	S	L	V	V	A	M	R	H	Y	S	E	E	E	I	W	Q	R	V	G	K	D	P	S	G	S	P	F	N	S	L	V	Q	L	E	M	E	Q	G	I	P	R	N	P	F	I	N	A	G	A
Secondary structure
SS confidence
Disorder																																															?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	V	V	C	D	M	L	Q	G	R	L	S	A	P	R	Q	R	M	L	E	V	V	R	G	L	S	G	V	S	D	I	S	Y	D	T	V	V	A	R	S	E	F	E	H	S	A	R	N	A	A	I	A	W	L	M	K	S	F	G	N
Secondary structure
SS confidence
Disorder							?	?	?	?	?	?																																			?													?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		F	H	H	D	V	T	T	V	L	Q	N	Y	F	H	Y	C	A	L	K	M	S	C	V	E	L	A	R	T	F	V	F	L	A	N	Q	G	K	A	I	H	I	D	E	P	V	V	T	P	M	Q	A	R	Q	I	N	A	L	M	A	T
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		S	G	M	Y	Q	N	A	G	E	F	A	W	R	V	G	L	P	A	K	S	G	V	G	G	G	I	V	A	I	V	P	H	E	M	A	I	A	V	W	S	P	E	L	D	D	A	G	N	S	L	A	G	I	A	V	L	E	Q	L	T
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.
Sequence		K	Q	L	G	R	S	V	Y
Secondary structure
SS confidence
Disorder						?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1u60 chain A Region: 7 - 308 Aligned: 300 Modelled: 302 Confidence: 100.0% Identity: 37% Fold: beta-lactamase/transpeptidase-like Superfamily: beta-lactamase/transpeptidase-like Family: Glutaminase Phyre2 PDB 3ih9 chain A Region: 4 - 308 Aligned: 302 Modelled: 305 Confidence: 100.0% Identity: 34% PDB header:hydrolase Chain: A: PDB Molecule:salt-tolerant glutaminase; PDBTitle: crystal structure analysis of mglu in its tris form Phyre2 PDB 2dfw chain A Region: 4 - 308 Aligned: 302 Modelled: 304 Confidence: 100.0% Identity: 34% PDB header:hydrolase Chain: A: PDB Molecule:salt-tolerant glutaminase; PDBTitle: crystal structure of a major fragment of the salt-tolerant2 glutaminase from micrococcus luteus k-3 Phyre2 PDB 3uo9 chain B Region: 8 - 308 Aligned: 293 Modelled: 294 Confidence: 100.0% Identity: 35% PDB header:hydrolase/hydrolase inhibitor Chain: B: PDB Molecule:glutaminase kidney isoform, mitochondrial; PDBTitle: crystal structure of human gac in complex with glutamate and bptes Phyre2 PDB 3czd chain A Region: 7 - 308 Aligned: 296 Modelled: 302 Confidence: 100.0% Identity: 35% PDB header:hydrolase Chain: A: PDB Molecule:glutaminase kidney isoform; PDBTitle: crystal structure of human glutaminase in complex with l-glutamate Phyre2 PDB 2pby chain B Region: 6 - 308 Aligned: 288 Modelled: 288 Confidence: 100.0% Identity: 42% PDB header:hydrolase Chain: B: PDB Molecule:glutaminase; PDBTitle: probable glutaminase from geobacillus kaustophilus hta426 Phyre2 PDB 3ss4 chain C Region: 8 - 308 Aligned: 292 Modelled: 293 Confidence: 100.0% Identity: 36% PDB header:hydrolase Chain: C: PDB Molecule:glutaminase c; PDBTitle: crystal structure of mouse glutaminase c, phosphate-bound form Phyre2 PDB 1mki chain A Region: 5 - 308 Aligned: 293 Modelled: 304 Confidence: 100.0% Identity: 35% Fold: beta-lactamase/transpeptidase-like Superfamily: beta-lactamase/transpeptidase-like Family: Glutaminase Phyre2 PDB 3dwk chain C Region: 3 - 279 Aligned: 229 Modelled: 251 Confidence: 97.6% Identity: 19% PDB header:transferase Chain: C: PDB Molecule:penicillin-binding protein 2; PDBTitle: identification of dynamic structural motifs involved in2 peptidoglycan glycosyltransfer Phyre2 PDB 3oc2 chain A Region: 61 - 303 Aligned: 206 Modelled: 213 Confidence: 97.5% Identity: 19% PDB header:penicillin-binding protein Chain: A: PDB Molecule:penicillin-binding protein 3; PDBTitle: crystal structure of penicillin-binding protein 3 from pseudomonas2 aeruginosa Phyre2 PDB 2dcf chain A domain 1 Region: 45 - 304 Aligned: 229 Modelled: 231 Confidence: 97.4% Identity: 20% Fold: beta-lactamase/transpeptidase-like Superfamily: beta-lactamase/transpeptidase-like Family: beta-Lactamase/D-ala carboxypeptidase Phyre2 PDB 2wad chain B Region: 7 - 306 Aligned: 279 Modelled: 300 Confidence: 97.4% Identity: 14% PDB header:peptide binding protein Chain: B: PDB Molecule:penicillin-binding protein 2b; PDBTitle: penicillin-binding protein 2b (pbp-2b) from streptococcus2 pneumoniae (strain 5204) Phyre2 PDB 3lo7 chain A Region: 58 - 304 Aligned: 205 Modelled: 215 Confidence: 97.3% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:penicillin-binding protein a; PDBTitle: crystal structure of pbpa from mycobacterium tuberculosis Phyre2 PDB 1k25 chain A domain 4 Region: 4 - 242 Aligned: 167 Modelled: 178 Confidence: 97.3% Identity: 23% Fold: beta-lactamase/transpeptidase-like Superfamily: beta-lactamase/transpeptidase-like Family: beta-Lactamase/D-ala carboxypeptidase Phyre2 PDB 2c5w chain B domain 1 Region: 4 - 304 Aligned: 260 Modelled: 271 Confidence: 97.2% Identity: 18% Fold: beta-lactamase/transpeptidase-like Superfamily: beta-lactamase/transpeptidase-like Family: beta-Lactamase/D-ala carboxypeptidase Phyre2 PDB 1vqq chain A domain 3 Region: 58 - 303 Aligned: 214 Modelled: 225 Confidence: 97.1% Identity: 16% Fold: beta-lactamase/transpeptidase-like Superfamily: beta-lactamase/transpeptidase-like Family: beta-Lactamase/D-ala carboxypeptidase Phyre2 PDB 1bue chain A Region: 25 - 304 Aligned: 245 Modelled: 269 Confidence: 97.0% Identity: 16% Fold: beta-lactamase/transpeptidase-like Superfamily: beta-lactamase/transpeptidase-like Family: beta-Lactamase/D-ala carboxypeptidase Phyre2 PDB 1n9b chain A Region: 30 - 303 Aligned: 221 Modelled: 233 Confidence: 96.9% Identity: 19% Fold: beta-lactamase/transpeptidase-like Superfamily: beta-lactamase/transpeptidase-like Family: beta-Lactamase/D-ala carboxypeptidase Phyre2 PDB 2olv chain A Region: 58 - 303 Aligned: 215 Modelled: 220 Confidence: 96.8% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:penicillin-binding protein 2; PDBTitle: structural insight into the transglycosylation step of bacterial cell2 wall biosynthesis : donor ligand complex Phyre2 PDB 1rp5 chain A domain 4 Region: 4 - 239 Aligned: 188 Modelled: 202 Confidence: 96.8% Identity: 18% Fold: beta-lactamase/transpeptidase-like Superfamily: beta-lactamase/transpeptidase-like Family: beta-Lactamase/D-ala carboxypeptidase Phyre2 1 d1u60a_ 2 c3ih9A_ 3 c2dfwA_ 4 c3uo9B_ 5 c3czdA_ 6 c2pbyB_ 7 c3ss4C_ 8 d1mkia_ 9 c3dwkC_ 10 c3oc2A_ 11 d2dcfa1 12 c2wadB_ 13 c3lo7A_ 14 d1k25a4 15 d2c5wb1 16 d1vqqa3 17 d1buea_ 18 d1n9ba_ 19 c2olvA_ 20 d1rp5a4 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1u60a_ 100.0 37 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:Glutaminase 2 c3ih9A_ 100.0 34 PDB header:hydrolase Chain: A: PDB Molecule:salt-tolerant glutaminase; PDBTitle: crystal structure analysis of mglu in its tris form 3 c2dfwA_ 100.0 34 PDB header:hydrolase Chain: A: PDB Molecule:salt-tolerant glutaminase; PDBTitle: crystal structure of a major fragment of the salt-tolerant2 glutaminase from micrococcus luteus k-3 4 c3uo9B_ 100.0 35 PDB header:hydrolase/hydrolase inhibitor Chain: B: PDB Molecule:glutaminase kidney isoform, mitochondrial; PDBTitle: crystal structure of human gac in complex with glutamate and bptes 5 c3czdA_ 100.0 35 PDB header:hydrolase Chain: A: PDB Molecule:glutaminase kidney isoform; PDBTitle: crystal structure of human glutaminase in complex with l-glutamate 6 c2pbyB_ 100.0 42 PDB header:hydrolase Chain: B: PDB Molecule:glutaminase; PDBTitle: probable glutaminase from geobacillus kaustophilus hta426 7 c3ss4C_ 100.0 36 PDB header:hydrolase Chain: C: PDB Molecule:glutaminase c; PDBTitle: crystal structure of mouse glutaminase c, phosphate-bound form 8 d1mkia_ 100.0 35 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:Glutaminase 9 c3dwkC_ 97.6 19 PDB header:transferase Chain: C: PDB Molecule:penicillin-binding protein 2; PDBTitle: identification of dynamic structural motifs involved in2 peptidoglycan glycosyltransfer 10 c3oc2A_ 97.5 19 PDB header:penicillin-binding protein Chain: A: PDB Molecule:penicillin-binding protein 3; PDBTitle: crystal structure of penicillin-binding protein 3 from pseudomonas2 aeruginosa 11 d2dcfa1 97.4 20 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 12 c2wadB_ 97.4 14 PDB header:peptide binding protein Chain: B: PDB Molecule:penicillin-binding protein 2b; PDBTitle: penicillin-binding protein 2b (pbp-2b) from streptococcus2 pneumoniae (strain 5204) 13 c3lo7A_ 97.3 21 PDB header:transferase Chain: A: PDB Molecule:penicillin-binding protein a; PDBTitle: crystal structure of pbpa from mycobacterium tuberculosis 14 d1k25a4 97.3 23 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 15 d2c5wb1 97.2 18 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 16 d1vqqa3 97.1 16 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 17 d1buea_ 97.0 16 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 18 d1n9ba_ 96.9 19 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 19 c2olvA_ 96.8 17 PDB header:transferase Chain: A: PDB Molecule:penicillin-binding protein 2; PDBTitle: structural insight into the transglycosylation step of bacterial cell2 wall biosynthesis : donor ligand complex 20 d1rp5a4 96.8 18 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 21 c3qhyA_ not modelled 96.8 15 PDB header:hydrolase/hydrolase inhibitor Chain: A: PDB Molecule:beta-lactamase; PDBTitle: structural, thermodynamic and kinetic analysis of the picomolar2 binding affinity interaction of the beta-lactamase inhibitor protein-3 ii (blip-ii) with class a beta-lactamases 22 c3pbqA_ not modelled 96.8 17 PDB header:hydrolase/antibiotic Chain: A: PDB Molecule:penicillin-binding protein 3; PDBTitle: crystal structure of pbp3 complexed with imipenem 23 c2jc7A_ not modelled 96.6 15 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase oxa-24; PDBTitle: the crystal structure of the carbapenemase oxa-24 reveals2 new insights into the mechanism of carbapenem-hydrolysis 24 d2olua2 not modelled 96.6 20 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 25 d1g6aa_ not modelled 96.5 13 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 26 d1pyya4 not modelled 96.5 20 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 27 c1qmfA_ not modelled 96.4 19 PDB header:peptidoglycan synthesis Chain: A: PDB Molecule:penicillin-binding protein 2x; PDBTitle: penicillin-binding protein 2x (pbp-2x) acyl-enzyme complex 28 c1w7fB_ not modelled 96.4 16 PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase; PDBTitle: crystal structure of the class a beta-lactamase bs32 inhibited with isocitrate 29 d1nrfa_ not modelled 96.4 15 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 30 c3udiA_ not modelled 96.3 25 PDB header:penicillin-binding protein/antibiotic Chain: A: PDB Molecule:penicillin-binding protein 1a; PDBTitle: crystal structure of acinetobacter baumannii pbp1a in complex with2 penicillin g 31 c2qpnA_ not modelled 96.3 16 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase ges-1; PDBTitle: ges-1 beta-lactamase 32 c1i2sA_ not modelled 96.3 18 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase; PDBTitle: beta-lactamase from bacillus licheniformis bs3 33 d1i2sa_ not modelled 96.3 18 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 34 c2bg1A_ not modelled 96.3 16 PDB header:peptidoglycan Chain: A: PDB Molecule:penicillin-binding protein 1b; PDBTitle: active site restructuring regulates ligand recognition in2 classa penicillin-binding proteins (pbps) 35 c3cg5A_ not modelled 96.2 16 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase; PDBTitle: crystal structure of the covalent adduct formed between tb2 b-lactamase and clavulanate 36 d1alqa_ not modelled 96.1 12 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 37 c2ov5A_ not modelled 96.0 15 PDB header:hydrolase Chain: A: PDB Molecule:carbapenemase; PDBTitle: crystal structure of the kpc-2 carbapenemase 38 d1bsga_ not modelled 95.6 22 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 39 c1mwuA_ not modelled 95.4 15 PDB header:biosynthetic protein Chain: A: PDB Molecule:penicillin-binding protein 2a; PDBTitle: structure of methicillin acyl-penicillin binding protein 2a2 from methicillin resistant staphylococcus aureus strain3 27r at 2.60 a resolution. 40 c2wuqA_ not modelled 95.3 14 PDB header:transcription Chain: A: PDB Molecule:beta-lactamase regulatory protein blab; PDBTitle: crystal structure of blab protein from streptomyces cacaoi 41 d1djaa_ not modelled 95.2 14 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 42 c3ue3A_ not modelled 95.2 21 PDB header:transferase Chain: A: PDB Molecule:septum formation, penicillin binding protein 3, PDBTitle: crystal structure of acinetobacter baumanni pbp3 43 c3i7jB_ not modelled 95.0 22 PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase mb2281c; PDBTitle: crystal structure of a beta-lactamase (mb2281c) from2 mycobacterium bovis, northeast structural genomics3 consortium target mbr246 44 d1e25a_ not modelled 94.8 20 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 45 c3lezA_ not modelled 94.6 17 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase; PDBTitle: crystal structure of a halotolerant bacterial beta-lactamase 46 d1dy6a_ not modelled 93.2 17 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 47 d1iysa_ not modelled 93.2 19 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 48 c3p09A_ not modelled 92.9 16 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase; PDBTitle: crystal structure of beta-lactamase from francisella tularensis 49 d1k55a_ not modelled 91.9 16 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 50 d2cc1a1 not modelled 91.4 16 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 51 c3dw0B_ not modelled 91.2 17 PDB header:hydrolase Chain: B: PDB Molecule:class a carbapenemase kpc-2; PDBTitle: crystal structure of the class a carbapenemase kpc-2 at 1.62 angstrom resolution 52 d1m6ka_ not modelled 90.1 20 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 53 d1m40a_ not modelled 90.1 21 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 54 c2v20A_ not modelled 90.0 23 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase tem; PDBTitle: structure of a tem-1 beta-lactamase insertant2 allosterically regulated by kanamycin and anions. complex3 with sulfate. 55 d1xa1a_ not modelled 89.7 12 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 56 c2wzzA_ not modelled 89.4 23 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase; PDBTitle: amp-c beta-lactamase (pseudomonas aeruginosa)in complex2 with compound m-03 57 d1w79a1 not modelled 88.6 17 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:Dac-like 58 c3a3eB_ not modelled 88.6 16 PDB header:hydrolase Chain: B: PDB Molecule:penicillin-binding protein 4; PDBTitle: crystal structure of penicillin binding protein 4 (dacb)2 from haemophilus influenzae, complexed with novel beta-3 lactam (cmv) 59 c1pmdA_ not modelled 88.5 27 PDB header:peptidoglycan synthesis Chain: A: PDB Molecule:peptidoglycan synthesis multifunctional enzyme; PDBTitle: penicillin-binding protein 2x (pbp-2x) 60 d1w5da1 not modelled 88.4 20 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:Dac-like 61 d2ex2a1 not modelled 87.9 13 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:Dac-like 62 d2bg1a1 not modelled 87.6 19 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 63 c3hbrD_ not modelled 87.3 13 PDB header:hydrolase Chain: D: PDB Molecule:oxa-48; PDBTitle: crystal structure of oxa-48 beta-lactamase 64 d3beca2 not modelled 87.1 16 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 65 c2qmiH_ not modelled 86.9 23 PDB header:hydrolase Chain: H: PDB Molecule:pbp related beta-lactamase; PDBTitle: structure of the octameric penicillin-binding protein2 homologue from pyrococcus abyssi 66 c2jciA_ not modelled 86.5 21 PDB header:drug-binding protein Chain: A: PDB Molecule:penicillin-binding protein 1b; PDBTitle: structural insights into the catalytic mechanism and the2 role of streptococcus pneumoniae pbp1b 67 c3cjmA_ not modelled 85.7 20 PDB header:hydrolase Chain: A: PDB Molecule:putative beta-lactamase; PDBTitle: crystal structure of putative beta-lactamase (np_815223.1) from2 enterococcus faecalis v583 at 1.50 a resolution 68 d1onha_ not modelled 85.2 19 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 69 d1yqsa1 not modelled 85.1 31 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 70 c3fwlA_ not modelled 85.0 26 PDB header:transferase, hydrolase Chain: A: PDB Molecule:penicillin-binding protein 1b; PDBTitle: crystal structure of the full-length transglycosylase pbp1b2 from escherichia coli 71 c3ozhA_ not modelled 84.5 21 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase/d-alanine carboxypeptidase; PDBTitle: crystal structure of beta-lactamase/d-alanine carboxypeptidase from2 yersinia pestis 72 c3equB_ not modelled 83.6 22 PDB header:biosynthetic protein Chain: B: PDB Molecule:penicillin-binding protein 2; PDBTitle: crystal structure of penicillin-binding protein 2 from neisseria2 gonorrhoeae 73 d1hzoa_ not modelled 83.5 26 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 74 c2j7vA_ not modelled 82.9 15 PDB header:hydrolase Chain: A: PDB Molecule:tll2115 protein; PDBTitle: structure of pbp-a 75 d1ci9a_ not modelled 82.1 19 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 76 d2hdsa1 not modelled 81.5 30 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 77 c1z6fA_ not modelled 80.8 16 PDB header:hydrolase Chain: A: PDB Molecule:penicillin-binding protein 5; PDBTitle: crystal structure of penicillin-binding protein 5 from e. coli in2 complex with a boronic acid inhibitor 78 c3hleA_ not modelled 78.8 14 PDB header:transferase Chain: A: PDB Molecule:transesterase; PDBTitle: simvastatin synthase (lovd), from aspergillus terreus, s5 mutant, s76a2 mutant, complex with monacolin j acid 79 d1k38a_ not modelled 78.7 17 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 80 d1tvfa2 not modelled 77.6 13 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 81 c3p09B_ not modelled 77.1 19 PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase; PDBTitle: crystal structure of beta-lactamase from francisella tularensis 82 c2iwdA_ not modelled 76.5 14 PDB header:antibiotic resistance Chain: A: PDB Molecule:methicillin resistance mecr1 protein; PDBTitle: oxacilloyl-acylated mecr1 extracellular antibiotic-sensor2 domain. 83 d1o7ea_ not modelled 76.1 22 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 84 c1zkjA_ not modelled 74.7 36 PDB header:hydrolase Chain: A: PDB Molecule:extended-spectrum beta-lactamase; PDBTitle: structural basis for the extended substrate spectrum of cmy-2 10, a plasmid-encoded class c beta-lactamase 85 c2bcfA_ not modelled 74.3 25 PDB header:hydrolase Chain: A: PDB Molecule:probable d-alanyl-d-alanine carboxypeptidase PDBTitle: crystal structure of a evolved putative penicillin-binding2 protein homolog, rv2911, from mycobacterium tuberculosis. 86 c2qz6A_ not modelled 72.8 23 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase; PDBTitle: first crystal structure of a psychrophile class c beta-2 lactamase 87 d1ei5a3 not modelled 71.9 24 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 88 c1ei5A_ not modelled 71.8 25 PDB header:hydrolase Chain: A: PDB Molecule:d-aminopeptidase; PDBTitle: crystal structure of a d-aminopeptidase from ochrobactrum2 anthropi 89 c1tvfA_ not modelled 71.1 13 PDB header:penicillin binding Chain: A: PDB Molecule:penicillin binding protein 4; PDBTitle: crystal structure of penicillin-binding protein 4 (pbp4)2 from staphylococcus aureus 90 c2wuqB_ not modelled 70.2 10 PDB header:transcription Chain: B: PDB Molecule:beta-lactamase regulatory protein blab; PDBTitle: crystal structure of blab protein from streptomyces cacaoi 91 d1xp4a2 not modelled 66.0 23 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 92 d2drwa1 not modelled 65.4 18 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 93 d1rgya_ not modelled 64.5 26 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 94 c3humB_ not modelled 64.5 15 PDB header:hydrolase/antibiotics Chain: B: PDB Molecule:penicillin-binding protein 4; PDBTitle: crystal structure of penicillin binding protein 4 from2 staphylococcus aureus col in complex with cefotaxime 95 c3it9B_ not modelled 63.6 21 PDB header:hydrolase Chain: B: PDB Molecule:d-alanyl-d-alanine carboxypeptidase dacc; PDBTitle: crystal structure of penicillin-binding protein 6 (pbp6)2 from e. coli in apo state 96 c3a3jA_ not modelled 63.2 16 PDB header:hydrolase Chain: A: PDB Molecule:pbp5; PDBTitle: crystal structures of penicillin binding protein 5 from2 haemophilus influenzae 97 d1es5a_ not modelled 58.5 24 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 98 c3tg9A_ not modelled 55.9 21 PDB header:penicillin binding protein Chain: A: PDB Molecule:penicillin-binding protein; PDBTitle: the crystal structure of penicillin binding protein from bacillus2 halodurans 99 c2cblA_ not modelled 55.5 24 PDB header:complex (proto-oncogene/peptide) Chain: A: PDB Molecule:proto-oncogene cbl; PDBTitle: n-terminal domain of cbl in complex with its binding site2 on zap-70 100 c3bunB_ not modelled 54.8 24 PDB header:ligase/signaling protein Chain: B: PDB Molecule:e3 ubiquitin-protein ligase cbl; PDBTitle: crystal structure of c-cbl-tkb domain complexed with its2 binding motif in sprouty4 101 c3if6C_ not modelled 54.2 26 PDB header:hydrolase Chain: C: PDB Molecule:oxa-46 oxacillinase; PDBTitle: crystal structure of oxa-46 beta-lactamase from p.2 aeruginosa 102 c2xftA_ not modelled 53.8 9 PDB header:hydrolase Chain: A: PDB Molecule:orf12; PDBTitle: structural and mechanistic studies on a cephalosporin esterase from2 the clavulanic acid biosynthesis pathway 103 c2obvA_ not modelled 48.0 19 PDB header:transferase Chain: A: PDB Molecule:s-adenosylmethionine synthetase isoform type-1; PDBTitle: crystal structure of the human s-adenosylmethionine synthetase 1 in2 complex with the product 104 d1qm4a1 not modelled 47.2 22 Fold:S-adenosylmethionine synthetase Superfamily:S-adenosylmethionine synthetase Family:S-adenosylmethionine synthetase 105 c3o3vB_ not modelled 45.6 18 PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase; PDBTitle: crystal structure of clbp peptidase domain 106 c3mfdB_ not modelled 41.5 26 PDB header:hydrolase Chain: B: PDB Molecule:d-alanyl-d-alanine carboxypeptidase dacb; PDBTitle: the structure of the beta-lactamase superfamily domain of d-alanyl-d-2 alanine carboxypeptidase from bacillus subtilis 107 c1xp4C_ not modelled 41.0 23 PDB header:hydrolase Chain: C: PDB Molecule:d-alanyl-d-alanine carboxypeptidase; PDBTitle: crystal structure of a peptidoglycan synthesis regulatory2 factor (pbp3) from streptococcus pneumoniae 108 d2p02a1 not modelled 38.6 25 Fold:S-adenosylmethionine synthetase Superfamily:S-adenosylmethionine synthetase Family:S-adenosylmethionine synthetase 109 c3rv2B_ not modelled 27.3 31 PDB header:transferase Chain: B: PDB Molecule:s-adenosylmethionine synthase; PDBTitle: crystal structure of s-adenosylmethionine synthetase from2 mycobacterium marinum 110 c2l02B_ not modelled 27.0 17 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: solution nmr structure of protein bt2368 from bacteroides2 thetaiotaomicron, northeast structural genomics consortium target3 btr375 111 d1a4ea_ not modelled 25.0 16 Fold:Heme-dependent catalase-like Superfamily:Heme-dependent catalase-like Family:Heme-dependent catalases 112 c3ik5A_ not modelled 24.5 15 PDB header:viral protein/signaling protein Chain: A: PDB Molecule:protein nef; PDBTitle: sivmac239 nef in complex with tcr zeta itam 1 polypeptide2 (a63-r80) 113 c3so4C_ not modelled 24.4 28 PDB header:transferase Chain: C: PDB Molecule:methionine-adenosyltransferase; PDBTitle: methionine-adenosyltransferase from entamoeba histolytica 114 d1efnb_ not modelled 22.9 15 Fold:Regulatory factor Nef Superfamily:Regulatory factor Nef Family:Regulatory factor Nef 115 d2g17a2 not modelled 22.3 63 Fold:FwdE/GAPDH domain-like Superfamily:Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain Family:GAPDH-like 116 d2nefa_ not modelled 21.7 15 Fold:Regulatory factor Nef Superfamily:Regulatory factor Nef Family:Regulatory factor Nef 117 d1chka_ not modelled 21.7 25 Fold:Lysozyme-like Superfamily:Lysozyme-like Family:Chitosanase 118 d1dnpa1 not modelled 21.1 21 Fold:Cryptochrome/photolyase FAD-binding domain Superfamily:Cryptochrome/photolyase FAD-binding domain Family:Cryptochrome/photolyase FAD-binding domain 119 c2xi1A_ not modelled 21.1 12 PDB header:viral protein Chain: A: PDB Molecule:nef; PDBTitle: crystal structure of the hiv-1 nef sequenced from a patient's sample 120 d2q49a2 not modelled 20.9 75 Fold:FwdE/GAPDH domain-like Superfamily:Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain Family:GAPDH-like

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0