PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2iwdA_

Fold library id	PDB Header	Molecule	Title
c2iwdA_	PDB header: antibiotic resistance	Chain: A: PDB Molecule: methicillin resistance mecr1 protein;	PDBTitle: oxacilloyl-acylated mecr1 extracellular antibiotic-sensor2 domain.

Links to external resources
Added to library: Tue Mar 16 13:17:16 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence D K Y E T N V S Y K K L N Q L A P Y F K G F D G S F V L Y N E R E Q A Y S I Y N E P E S K Q R Y S P N T Y K I Y L A L M A F D Q N L L S L N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
B
G G G G G G G T T S T T T T S B
T T T S S B T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence H T E Q Q W D K H Q Y P F K E W N Q D Q N L N S S M K Y S V N W Y Y E N L N K H L R Q D E V K S Y L D L I E Y G N E E I S G N E N Y W N E S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) B
B
S S G G G S S
B
T T
S
T
T T
S
T T T T S S S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence S L K I S A I E Q V N L L K N M K Q H N M H F D N K A I E K V E N S M T L K Q K D T Y K Y V G K T G T G I V N H K E A N G W F V G Y V E T K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T
S S S
T
S S T T S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . .

Sequence D N T Y Y F A T H L K G E D N A N G E K A Q Q I S E R I L K E M E L I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S S
B S T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	D	K	Y	E	T	N	V	S	Y	K	K	L	N	Q	L	A	P	Y	F	K	G	F	D	G	S	F	V	L	Y	N	E	R	E	Q	A	Y	S	I	Y	N	E	P	E	S	K	Q	R	Y	S	P	N	T	Y	K	I	Y	L	A	L	M	A	F	D	Q	N	L	L	S	L	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		B											G	G	G	G	G	G	G	T	T	S									T	T	T	T						S						B							T											T	T	S	S	B	T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	H	T	E	Q	Q	W	D	K	H	Q	Y	P	F	K	E	W	N	Q	D	Q	N	L	N	S	S	M	K	Y	S	V	N	W	Y	Y	E	N	L	N	K	H	L	R	Q	D	E	V	K	S	Y	L	D	L	I	E	Y	G	N	E	E	I	S	G	N	E	N	Y	W	N	E	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	B			B								S	S	G	G	G	S	S		B								T	T												S													T		T	T					S		T	T	T	T	S	S	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	S	L	K	I	S	A	I	E	Q	V	N	L	L	K	N	M	K	Q	H	N	M	H	F	D	N	K	A	I	E	K	V	E	N	S	M	T	L	K	Q	K	D	T	Y	K	Y	V	G	K	T	G	T	G	I	V	N	H	K	E	A	N	G	W	F	V	G	Y	V	E	T	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S																	T	T		S	S	S												T						S	S													T	T														S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.
Sequence	D	N	T	Y	Y	F	A	T	H	L	K	G	E	D	N	A	N	G	E	K	A	Q	Q	I	S	E	R	I	L	K	E	M	E	L	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S												S	S		B	S															T	T