Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	K	L	I	N	D	V	Q	D	V	L	D	E	Q	L	A	G	L	A	K	A	H	P	S	L	T	L	H	Q	D	P	V	Y	V	T	R	A	D	A	P	V	A	G	K	V	A	L	L	S	G	G	G	S	G	H	E	P	M	H
Secondary structure
SS confidence
Disorder		?	?	?	?																																								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		C	G	Y	I	G	Q	G	M	L	S	G	A	C	P	G	E	I	F	T	S	P	T	P	D	K	I	F	E	C	A	M	Q	V	D	G	G	E	G	V	L	L	I	I	K	N	Y	T	G	D	I	L	N	F	E	T	A	T	E	L	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		H	D	S	G	V	K	V	T	T	V	V	I	D	D	D	V	A	V	K	D	S	L	Y	T	A	G	R	R	G	V	A	N	T	V	L	I	E	K	L	V	G	A	A	A	E	R	G	D	S	L	D	A	C	A	E	L	G	R	K	L
Secondary structure
SS confidence
Disorder																			?	?	?	?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		N	N	Q	G	H	S	I	G	I	A	L	G	A	C	T	V	P	A	A	G	K	P	S	F	T	L	A	D	N	E	M	E	F	G	V	G	I	H	G	E	P	G	I	D	R	R	P	F	S	S	L	D	Q	T	V	D	E	M	F	D
Secondary structure
SS confidence
Disorder																						?	?	?	?	?	?	?																				?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		T	L	L	V	N	G	S	Y	H	R	T	L	R	F	W	D	Y	Q	Q	G	S	W	Q	E	E	Q	Q	T	K	Q	P	L	Q	S	G	D	R	V	I	A	L	V	N	N	L	G	A	T	P	L	S	E	L	Y	G	V	Y	N	R	L
Secondary structure
SS confidence
Disorder								?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.
Sequence		T	T	R	C	Q	Q	A	G	L	T	I	E	R	N	L	I	G	A	Y	C	T	S	L	D	M	T	G	F	S	I	T	L	L	K	V	D	D	E	T	L	A	L	W	D	A	P	V	H	T	P	A	L	N	W	G	K
Secondary structure
SS confidence
Disorder																																																				?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1oi2 chain A Region: 10 - 356 Aligned: 336 Modelled: 347 Confidence: 100.0% Identity: 100% Fold: DAK1/DegV-like Superfamily: DAK1/DegV-like Family: DAK1 Phyre2 PDB 1un8 chain A domain 4 Region: 1 - 355 Aligned: 324 Modelled: 329 Confidence: 100.0% Identity: 32% Fold: DAK1/DegV-like Superfamily: DAK1/DegV-like Family: DAK1 Phyre2 PDB 1un9 chain B Region: 1 - 355 Aligned: 324 Modelled: 329 Confidence: 100.0% Identity: 32% PDB header:kinase Chain: B: PDB Molecule:dihydroxyacetone kinase; PDBTitle: crystal structure of the dihydroxyacetone kinase from c.2 freundii in complex with amp-pnp and mg2+ Phyre2 PDB 3ct4 chain B Region: 2 - 352 Aligned: 317 Modelled: 327 Confidence: 100.0% Identity: 46% PDB header:transferase Chain: B: PDB Molecule:pts-dependent dihydroxyacetone kinase, PDBTitle: structure of dha-kinase subunit dhak from l. lactis Phyre2 PDB 2iu6 chain B Region: 3 - 354 Aligned: 315 Modelled: 330 Confidence: 100.0% Identity: 34% PDB header:transferase Chain: B: PDB Molecule:dihydroxyacetone kinase; PDBTitle: regulation of the dha operon of lactococcus lactis Phyre2 PDB 3pl5 chain A Region: 79 - 187 Aligned: 97 Modelled: 109 Confidence: 95.3% Identity: 16% PDB header:lipid binding protein Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: fatty acid binding protein Phyre2 PDB 3jr7 chain A Region: 79 - 187 Aligned: 97 Modelled: 109 Confidence: 94.5% Identity: 15% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized egv family protein cog1307; PDBTitle: the crystal structure of the protein of degv family cog1307 with2 unknown function from ruminococcus gnavus atcc 29149 Phyre2 PDB 1pzx chain A Region: 79 - 187 Aligned: 97 Modelled: 109 Confidence: 93.3% Identity: 14% Fold: DAK1/DegV-like Superfamily: DAK1/DegV-like Family: DegV-like Phyre2 PDB 1mgp chain A Region: 79 - 333 Aligned: 197 Modelled: 217 Confidence: 93.2% Identity: 16% PDB header:lipid binding protein Chain: A: PDB Molecule:hypothetical protein tm841; PDBTitle: hypothetical protein tm841 from thermotoga maritima reveals2 fatty acid binding function Phyre2 PDB 1mgp chain A Region: 79 - 333 Aligned: 197 Modelled: 217 Confidence: 93.2% Identity: 16% Fold: DAK1/DegV-like Superfamily: DAK1/DegV-like Family: DegV-like Phyre2 PDB 3ct6 chain A domain 1 Region: 82 - 180 Aligned: 74 Modelled: 82 Confidence: 92.7% Identity: 16% Fold: PTS system fructose IIA component-like Superfamily: PTS system fructose IIA component-like Family: DhaM-like Phyre2 PDB 2bz1 chain A domain 1 Region: 34 - 130 Aligned: 92 Modelled: 97 Confidence: 91.9% Identity: 27% Fold: RibA-like Superfamily: RibA-like Family: RibA-like Phyre2 PDB 3nyi chain A Region: 79 - 187 Aligned: 97 Modelled: 109 Confidence: 91.4% Identity: 16% PDB header:lipid binding protein Chain: A: PDB Molecule:fat acid-binding protein; PDBTitle: the crystal structure of a fat acid (stearic acid)-binding protein2 from eubacterium ventriosum atcc 27560. Phyre2 PDB 3fdj chain A Region: 79 - 187 Aligned: 94 Modelled: 109 Confidence: 88.8% Identity: 16% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:degv family protein; PDBTitle: the structure of a degv family protein from eubacterium eligens. Phyre2 PDB 3gdw chain A Region: 83 - 183 Aligned: 77 Modelled: 84 Confidence: 86.9% Identity: 19% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:sigma-54 interaction domain protein; PDBTitle: crystal structure of sigma-54 interaction domain protein from2 enterococcus faecalis Phyre2 PDB 2dt8 chain A Region: 79 - 187 Aligned: 92 Modelled: 109 Confidence: 86.8% Identity: 21% PDB header:lipid binding protein Chain: A: PDB Molecule:degv family protein; PDBTitle: fatty acid binding of a degv family protein from thermus thermophilus Phyre2 PDB 3b48 chain A domain 1 Region: 82 - 179 Aligned: 78 Modelled: 79 Confidence: 82.3% Identity: 22% Fold: PTS system fructose IIA component-like Superfamily: PTS system fructose IIA component-like Family: DhaM-like Phyre2 PDB 1hf2 chain A domain 2 Region: 235 - 319 Aligned: 61 Modelled: 66 Confidence: 69.5% Identity: 18% Fold: Cell-division inhibitor MinC, N-terminal domain Superfamily: Cell-division inhibitor MinC, N-terminal domain Family: Cell-division inhibitor MinC, N-terminal domain Phyre2 PDB 3c3j chain A Region: 41 - 184 Aligned: 140 Modelled: 144 Confidence: 65.5% Identity: 19% PDB header:isomerase Chain: A: PDB Molecule:putative tagatose-6-phosphate ketose/aldose isomerase; PDBTitle: crystal structure of tagatose-6-phosphate ketose/aldose isomerase from2 escherichia coli Phyre2 PDB 2g7z chain B Region: 79 - 187 Aligned: 92 Modelled: 97 Confidence: 64.3% Identity: 13% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:conserved hypothetical protein spy1493; PDBTitle: conserved degv-like protein of unknown function from streptococcus2 pyogenes m1 gas binds long-chain fatty acids Phyre2 1 d1oi2a_ 2 d1un8a4 3 c1un9B_ 4 c3ct4B_ 5 c2iu6B_ 6 c3pl5A_ 7 c3jr7A_ 8 d1pzxa_ 9 c1mgpA_ 10 d1mgpa_ 11 d3ct6a1 12 d2bz1a1 13 c3nyiA_ 14 c3fdjA_ 15 c3gdwA_ 16 c2dt8A_ 17 d3b48a1 18 d1hf2a2 19 c3c3jA_ 20 c2g7zB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1oi2a_ 100.0 100 Fold:DAK1/DegV-like Superfamily:DAK1/DegV-like Family:DAK1 2 d1un8a4 100.0 32 Fold:DAK1/DegV-like Superfamily:DAK1/DegV-like Family:DAK1 3 c1un9B_ 100.0 32 PDB header:kinase Chain: B: PDB Molecule:dihydroxyacetone kinase; PDBTitle: crystal structure of the dihydroxyacetone kinase from c.2 freundii in complex with amp-pnp and mg2+ 4 c3ct4B_ 100.0 46 PDB header:transferase Chain: B: PDB Molecule:pts-dependent dihydroxyacetone kinase, PDBTitle: structure of dha-kinase subunit dhak from l. lactis 5 c2iu6B_ 100.0 34 PDB header:transferase Chain: B: PDB Molecule:dihydroxyacetone kinase; PDBTitle: regulation of the dha operon of lactococcus lactis 6 c3pl5A_ 95.3 16 PDB header:lipid binding protein Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: fatty acid binding protein 7 c3jr7A_ 94.5 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized egv family protein cog1307; PDBTitle: the crystal structure of the protein of degv family cog1307 with2 unknown function from ruminococcus gnavus atcc 29149 8 d1pzxa_ 93.3 14 Fold:DAK1/DegV-like Superfamily:DAK1/DegV-like Family:DegV-like 9 c1mgpA_ 93.2 16 PDB header:lipid binding protein Chain: A: PDB Molecule:hypothetical protein tm841; PDBTitle: hypothetical protein tm841 from thermotoga maritima reveals2 fatty acid binding function 10 d1mgpa_ 93.2 16 Fold:DAK1/DegV-like Superfamily:DAK1/DegV-like Family:DegV-like 11 d3ct6a1 92.7 16 Fold:PTS system fructose IIA component-like Superfamily:PTS system fructose IIA component-like Family:DhaM-like 12 d2bz1a1 91.9 27 Fold:RibA-like Superfamily:RibA-like Family:RibA-like 13 c3nyiA_ 91.4 16 PDB header:lipid binding protein Chain: A: PDB Molecule:fat acid-binding protein; PDBTitle: the crystal structure of a fat acid (stearic acid)-binding protein2 from eubacterium ventriosum atcc 27560. 14 c3fdjA_ 88.8 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:degv family protein; PDBTitle: the structure of a degv family protein from eubacterium eligens. 15 c3gdwA_ 86.9 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:sigma-54 interaction domain protein; PDBTitle: crystal structure of sigma-54 interaction domain protein from2 enterococcus faecalis 16 c2dt8A_ 86.8 21 PDB header:lipid binding protein Chain: A: PDB Molecule:degv family protein; PDBTitle: fatty acid binding of a degv family protein from thermus thermophilus 17 d3b48a1 82.3 22 Fold:PTS system fructose IIA component-like Superfamily:PTS system fructose IIA component-like Family:DhaM-like 18 d1hf2a2 69.5 18 Fold:Cell-division inhibitor MinC, N-terminal domain Superfamily:Cell-division inhibitor MinC, N-terminal domain Family:Cell-division inhibitor MinC, N-terminal domain 19 c3c3jA_ 65.5 19 PDB header:isomerase Chain: A: PDB Molecule:putative tagatose-6-phosphate ketose/aldose isomerase; PDBTitle: crystal structure of tagatose-6-phosphate ketose/aldose isomerase from2 escherichia coli 20 c2g7zB_ 64.3 13 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:conserved hypothetical protein spy1493; PDBTitle: conserved degv-like protein of unknown function from streptococcus2 pyogenes m1 gas binds long-chain fatty acids 21 c3lupA_ not modelled 61.5 11 PDB header:structure genomics, unknown function Chain: A: PDB Molecule:degv family protein; PDBTitle: crystal structure of fatty acid binding degv family protein sag13422 from streptococcus agalactiae 22 c3h7aC_ not modelled 57.8 14 PDB header:oxidoreductase Chain: C: PDB Molecule:short chain dehydrogenase; PDBTitle: crystal structure of short-chain dehydrogenase from2 rhodopseudomonas palustris 23 c3gndC_ not modelled 54.2 26 PDB header:lyase Chain: C: PDB Molecule:aldolase lsrf; PDBTitle: crystal structure of e. coli lsrf in complex with ribulose-5-phosphate 24 c3t4xA_ not modelled 51.9 39 PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase, short chain dehydrogenase/reductase family; PDBTitle: short chain dehydrogenase/reductase family oxidoreductase from2 bacillus anthracis str. ames ancestor 25 c3rd5A_ not modelled 47.4 39 PDB header:oxidoreductase Chain: A: PDB Molecule:mypaa.01249.c; PDBTitle: crystal structure of a putative uncharacterized protein from2 mycobacterium paratuberculosis 26 c3i1jB_ not modelled 45.7 38 PDB header:oxidoreductase Chain: B: PDB Molecule:oxidoreductase, short chain PDBTitle: structure of a putative short chain dehydrogenase from2 pseudomonas syringae 27 d2o23a1 not modelled 45.0 54 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 28 c3uxyC_ not modelled 44.9 54 PDB header:oxidoreductase Chain: C: PDB Molecule:short-chain dehydrogenase/reductase sdr; PDBTitle: the crystal structure of short chain dehydrogenase from rhodobacter2 sphaeroides 29 c3pxxE_ not modelled 44.7 46 PDB header:oxidoreductase Chain: E: PDB Molecule:carveol dehydrogenase; PDBTitle: crystal structure of carveol dehydrogenase from mycobacterium avium2 bound to nicotinamide adenine dinucleotide 30 c3s55F_ not modelled 42.2 54 PDB header:oxidoreductase Chain: F: PDB Molecule:putative short-chain dehydrogenase/reductase; PDBTitle: crystal structure of a putative short-chain dehydrogenase/reductase2 from mycobacterium abscessus bound to nad 31 c3qivA_ not modelled 41.8 38 PDB header:oxidoreductase Chain: A: PDB Molecule:short-chain dehydrogenase or 3-oxoacyl-[acyl-carrier- PDBTitle: crystal structure of a putative short-chain dehydrogenase or 3-2 oxoacyl-[acyl-carrier-protein] reductase from mycobacterium3 paratuberculosis atcc baa-968 / k-10 32 c3bmrA_ not modelled 40.7 15 PDB header:oxidoreductase Chain: A: PDB Molecule:pteridine reductase; PDBTitle: structure of pteridine reductase 1 (ptr1) from trypanosoma2 brucei in ternary complex with cofactor (nadp+) and3 inhibitor (compound ax6) 33 c3sc4A_ not modelled 40.6 46 PDB header:oxidoreductase Chain: A: PDB Molecule:short chain dehydrogenase (a0qtm2 homolog); PDBTitle: crystal structure of a short chain dehydrogenase (a0qtm2 homolog)2 mycobacterium thermoresistibile 34 c3oidA_ not modelled 40.3 38 PDB header:oxidoreductase Chain: A: PDB Molecule:enoyl-[acyl-carrier-protein] reductase [nadph]; PDBTitle: crystal structure of enoyl-acp reductases iii (fabl) from b. subtilis2 (complex with nadp and tcl) 35 c3ftpD_ not modelled 40.1 29 PDB header:oxidoreductase Chain: D: PDB Molecule:3-oxoacyl-[acyl-carrier protein] reductase; PDBTitle: crystal structure of 3-ketoacyl-(acyl-carrier-protein)2 reductase from burkholderia pseudomallei at 2.05 a3 resolution 36 d1vl8a_ not modelled 40.0 54 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 37 c3sx2F_ not modelled 39.1 46 PDB header:oxidoreductase Chain: F: PDB Molecule:putative 3-ketoacyl-(acyl-carrier-protein) reductase; PDBTitle: crystal structure of a putative 3-ketoacyl-(acyl-carrier-protein)2 reductase from mycobacterium paratuberculosis in complex with nad 38 c3uveC_ not modelled 39.0 46 PDB header:oxidoreductase Chain: C: PDB Molecule:carveol dehydrogenase ((+)-trans-carveol dehydrogenase); PDBTitle: crystal structure of carveol dehydrogenase ((+)-trans-carveol2 dehydrogenase) from mycobacterium avium 39 c2ntnB_ not modelled 38.9 33 PDB header:oxidoreductase Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase; PDBTitle: crystal structure of maba-c60v/g139a/s144l 40 d2ag5a1 not modelled 38.7 38 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 41 c3un1D_ not modelled 38.7 31 PDB header:oxidoreductase Chain: D: PDB Molecule:probable oxidoreductase; PDBTitle: crystal structure of an oxidoreductase from sinorhizobium meliloti2 1021 42 d1e6wa_ not modelled 37.8 54 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 43 c3gx1A_ not modelled 37.8 24 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:lin1832 protein; PDBTitle: crystal structure of a domain of lin1832 from listeria innocua 44 c3kvoB_ not modelled 37.7 31 PDB header:oxidoreductase Chain: B: PDB Molecule:hydroxysteroid dehydrogenase-like protein 2; PDBTitle: crystal structure of the catalytic domain of human hydroxysteroid2 dehydrogenase like 2 (hsdl2) 45 d1ae1a_ not modelled 37.6 35 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 46 c2pd6D_ not modelled 37.6 46 PDB header:oxidoreductase Chain: D: PDB Molecule:estradiol 17-beta-dehydrogenase 8; PDBTitle: structure of human hydroxysteroid dehydrogenase type 8, hsd17b8 47 c1w4zA_ not modelled 37.5 40 PDB header:antibiotic biosynthesis Chain: A: PDB Molecule:ketoacyl reductase; PDBTitle: structure of actinorhodin polyketide (actiii) reductase 48 c3gafF_ not modelled 37.2 31 PDB header:oxidoreductase Chain: F: PDB Molecule:7-alpha-hydroxysteroid dehydrogenase; PDBTitle: 2.2a crystal structure of 7-alpha-hydroxysteroid2 dehydrogenase from brucella melitensis 49 d1xkqa_ not modelled 36.9 27 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 50 c2ekqB_ not modelled 36.9 42 PDB header:oxidoreductase Chain: B: PDB Molecule:2-deoxy-d-gluconate 3-dehydrogenase; PDBTitle: structure of tt0495 protein from thermus thermophilus 51 c3lf2B_ not modelled 36.6 46 PDB header:oxidoreductase Chain: B: PDB Molecule:short chain oxidoreductase q9hya2; PDBTitle: nadph bound structure of the short chain oxidoreductase q9hya2 from2 pseudomonas aeruginosa pao1 containing an atypical catalytic center 52 d1q7ba_ not modelled 36.5 46 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 53 d2a4ka1 not modelled 36.4 46 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 54 c3nywD_ not modelled 36.2 23 PDB header:oxidoreductase Chain: D: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of a betaketoacyl-[acp] reductase (fabg) from2 bacteroides thetaiotaomicron 55 d1p33a_ not modelled 36.1 31 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 56 c2q2qG_ not modelled 36.0 54 PDB header:oxidoreductase Chain: G: PDB Molecule:beta-d-hydroxybutyrate dehydrogenase; PDBTitle: structure of d-3-hydroxybutyrate dehydrogenase from pseudomonas putida 57 d1o5ia_ not modelled 36.0 23 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 58 c3t7cC_ not modelled 35.9 46 PDB header:oxidoreductase Chain: C: PDB Molecule:carveol dehydrogenase; PDBTitle: crystal structure of carveol dehydrogenase from mycobacterium avium2 bound to nad 59 d1h5qa_ not modelled 35.7 24 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 60 c3rkuC_ not modelled 35.6 38 PDB header:oxidoreductase Chain: C: PDB Molecule:oxidoreductase ymr226c; PDBTitle: substrate fingerprint and the structure of nadp+ dependent serine2 dehydrogenase from saccharomyces cerevisiae complexed with nadp+ 61 c2nq8B_ not modelled 35.5 25 PDB header:oxidoreductase Chain: B: PDB Molecule:enoyl-acyl carrier reductase; PDBTitle: malarial enoyl acyl acp reductase bound with inh-nad adduct 62 c2foiB_ not modelled 35.5 25 PDB header:oxidoreductase Chain: B: PDB Molecule:enoyl-acyl carrier reductase; PDBTitle: synthesis, biological activity, and x-ray crystal structural analysis2 of diaryl ether inhibitors of malarial enoyl acp reductase. 63 c3r3sD_ not modelled 35.5 46 PDB header:oxidoreductase Chain: D: PDB Molecule:oxidoreductase; PDBTitle: structure of the ygha oxidoreductase from salmonella enterica 64 d1cyda_ not modelled 35.2 46 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 65 c2fwmX_ not modelled 35.2 38 PDB header:oxidoreductase Chain: X: PDB Molecule:2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase; PDBTitle: crystal structure of e. coli enta, a 2,3-dihydrodihydroxy benzoate2 dehydrogenase 66 c3nugA_ not modelled 35.1 54 PDB header:oxidoreductase Chain: A: PDB Molecule:3-oxoacyl-(acyl-carrier protein) reductase; PDBTitle: crystal structure of wild type tetrameric pyridoxal 4-dehydrogenase2 from mesorhizobium loti 67 c3f5sA_ not modelled 34.9 23 PDB header:oxidoreductase Chain: A: PDB Molecule:dehydrogenase; PDBTitle: crystal structure of putatitve short chain dehydrogenase from shigella2 flexneri 2a str. 301 68 d1uaya_ not modelled 34.9 50 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 69 c3diiB_ not modelled 34.8 33 PDB header:oxidoreductase Chain: B: PDB Molecule:short-chain dehydrogenase/reductase sdr; PDBTitle: crystal structure of a carbohydrate specific scor enzyme2 from clostridium thermocellum, ligand-free form 70 d1oaaa_ not modelled 34.7 31 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 71 c3ioyB_ not modelled 34.6 46 PDB header:oxidoreductase Chain: B: PDB Molecule:short-chain dehydrogenase/reductase sdr; PDBTitle: structure of putative short-chain dehydrogenase (saro_0793)2 from novosphingobium aromaticivorans 72 c2wdzD_ not modelled 34.6 46 PDB header:oxidoreductase Chain: D: PDB Molecule:short-chain dehydrogenase/reductase; PDBTitle: crystal structure of the short chain dehydrogenase2 galactitol-dehydrogenase (gatdh) of rhodobacter3 sphaeroides in complex with nad+ and 1,2-pentandiol 73 c2ptgA_ not modelled 34.3 46 PDB header:oxidoreductase Chain: A: PDB Molecule:enoyl-acyl carrier reductase; PDBTitle: crystal structure of eimeria tenella enoyl reductase 74 d2gdza1 not modelled 34.2 54 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 75 d1ulsa_ not modelled 33.8 31 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 76 d1xq1a_ not modelled 33.6 29 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 77 d1g0oa_ not modelled 33.6 62 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 78 d2ew8a1 not modelled 33.5 38 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 79 d1xg5a_ not modelled 33.5 31 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 80 c3a28H_ not modelled 33.4 50 PDB header:oxidoreductase Chain: H: PDB Molecule:l-2.3-butanediol dehydrogenase; PDBTitle: crystal structure of l-2,3-butanediol dehydrogenase 81 d1tqha_ not modelled 33.4 16 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase/lipase 82 c3e9nB_ not modelled 33.3 36 PDB header:oxidoreductase Chain: B: PDB Molecule:putative short-chain dehydrogenase/reductase; PDBTitle: crystal structure of a putative short-chain2 dehydrogenase/reductase from corynebacterium glutamicum 83 c3o38D_ not modelled 32.9 46 PDB header:oxidoreductase Chain: D: PDB Molecule:short chain dehydrogenase; PDBTitle: crystal structure of a short chain dehydrogenase from mycobacterium2 smegmatis 84 c2p68A_ not modelled 32.9 46 PDB header:oxidoreductase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase; PDBTitle: crystal structure of aq_1716 from aquifex aeolicus vf5 85 d2d1ya1 not modelled 32.6 54 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 86 c3toxG_ not modelled 32.5 46 PDB header:oxidoreductase Chain: G: PDB Molecule:short chain dehydrogenase; PDBTitle: crystal structure of a short chain dehydrogenase in complex with2 nad(p) from sinorhizobium meliloti 1021 87 d1e7wa_ not modelled 32.5 36 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 88 c3e03C_ not modelled 32.3 31 PDB header:oxidoreductase Chain: C: PDB Molecule:short chain dehydrogenase; PDBTitle: crystal structure of a putative dehydrogenase from2 xanthomonas campestris 89 c2zatC_ not modelled 32.2 38 PDB header:oxidoreductase Chain: C: PDB Molecule:dehydrogenase/reductase sdr family member 4; PDBTitle: crystal structure of a mammalian reductase 90 c3oecA_ not modelled 32.2 46 PDB header:oxidoreductase Chain: A: PDB Molecule:carveol dehydrogenase (mytha.01326.c, a0r518 homolog); PDBTitle: crystal structure of carveol dehydrogenase from mycobacterium2 thermoresistibile 91 d1k2wa_ not modelled 32.0 46 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 92 c3pgxB_ not modelled 31.8 38 PDB header:oxidoreductase Chain: B: PDB Molecule:carveol dehydrogenase; PDBTitle: crystal structure of a putative carveol dehydrogenase from2 mycobacterium paratuberculosis bound to nicotinamide adenine3 dinucleotide 93 c2hq1A_ not modelled 31.8 38 PDB header:oxidoreductase Chain: A: PDB Molecule:glucose/ribitol dehydrogenase; PDBTitle: crystal structure of orf 1438 a putative glucose/ribitol2 dehydrogenase from clostridium thermocellum 94 d1pr9a_ not modelled 31.8 46 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 95 c3shoA_ not modelled 31.7 13 PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator, rpir family; PDBTitle: crystal structure of rpir transcription factor from sphaerobacter2 thermophilus (sugar isomerase domain) 96 d1d7oa_ not modelled 31.6 29 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 97 d1gz6a_ not modelled 31.3 46 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 98 d1nffa_ not modelled 31.3 69 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 99 c2jahB_ not modelled 31.2 62 PDB header:oxidoreductase Chain: B: PDB Molecule:clavulanic acid dehydrogenase; PDBTitle: biochemical and structural analysis of the clavulanic acid2 dehydeogenase (cad) from streptomyces clavuligerus 100 d1ydea1 not modelled 31.2 62 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 101 d1bdba_ not modelled 31.2 46 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 102 c3ctmH_ not modelled 31.1 46 PDB header:oxidoreductase Chain: H: PDB Molecule:carbonyl reductase; PDBTitle: crystal structure of a carbonyl reductase from candida2 parapsilosis with anti-prelog stereo-specificity 103 c3ijrF_ not modelled 31.1 54 PDB header:oxidoreductase Chain: F: PDB Molecule:oxidoreductase, short chain dehydrogenase/reductase family; PDBTitle: 2.05 angstrom resolution crystal structure of a short chain2 dehydrogenase from bacillus anthracis str. 'ames ancestor' in complex3 with nad+ 104 c3qljB_ not modelled 30.9 38 PDB header:oxidoreductase Chain: B: PDB Molecule:short chain dehydrogenase; PDBTitle: crystal structure of a short chain dehydrogenase from mycobacterium2 avium 105 d1uzma1 not modelled 30.8 33 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 106 d1zk4a1 not modelled 30.7 54 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 107 d1spxa_ not modelled 30.6 46 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 108 d2rhca1 not modelled 30.5 46 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 109 c3fysA_ not modelled 30.5 7 PDB header:fatty acid-binding protein Chain: A: PDB Molecule:protein degv; PDBTitle: crystal structure of degv, a fatty acid binding protein2 from bacillus subtilis 110 c3r1iB_ not modelled 30.4 46 PDB header:oxidoreductase Chain: B: PDB Molecule:short-chain type dehydrogenase/reductase; PDBTitle: crystal structure of a short-chain type dehydrogenase/reductase from2 mycobacterium marinum 111 c3gvcB_ not modelled 30.4 62 PDB header:oxidoreductase Chain: B: PDB Molecule:probable short-chain type PDBTitle: crystal structure of probable short-chain dehydrogenase-2 reductase from mycobacterium tuberculosis 112 c3uf0A_ not modelled 30.3 54 PDB header:oxidoreductase Chain: A: PDB Molecule:short-chain dehydrogenase/reductase sdr; PDBTitle: crystal structure of a putative nad(p) dependent gluconate 5-2 dehydrogenase from beutenbergia cavernae(efi target efi-502044) with3 bound nadp (low occupancy) 113 d2fr1a1 not modelled 30.2 29 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 114 c3ppiA_ not modelled 30.2 46 PDB header:oxidoreductase Chain: A: PDB Molecule:3-hydroxyacyl-coa dehydrogenase type-2; PDBTitle: crystal structure of 3-hydroxyacyl-coa dehydrogenase type-2 from2 mycobacterium avium 115 d2bd0a1 not modelled 30.1 33 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 116 c3afnC_ not modelled 30.0 38 PDB header:oxidoreductase Chain: C: PDB Molecule:carbonyl reductase; PDBTitle: crystal structure of aldose reductase a1-r complexed with nadp 117 c3emkA_ not modelled 30.0 38 PDB header:oxidoreductase Chain: A: PDB Molecule:glucose/ribitol dehydrogenase; PDBTitle: 2.5a crystal structure of glucose/ribitol dehydrogenase2 from brucella melitensis 118 c1yb1B_ not modelled 30.0 33 PDB header:oxidoreductase Chain: B: PDB Molecule:17-beta-hydroxysteroid dehydrogenase type xi; PDBTitle: crystal structure of human 17-beta-hydroxysteroid dehydrogenase type2 xi 119 c2z1nA_ not modelled 29.6 41 PDB header:oxidoreductase Chain: A: PDB Molecule:dehydrogenase; PDBTitle: crystal structure of ape0912 from aeropyrum pernix k1 120 d2ae2a_ not modelled 29.6 35 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0