Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	D	I	S	K	A	S	L	P	K	A	I	F	L	M	G	P	T	A	S	G	K	T	A	L	A	I	E	L	R	K	I	L	P	V	E	L	I	S	V	D	S	A	L	I	Y	K	G	M	D	I	G	T	A	K	P	N	A	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		E	L	L	A	A	P	H	R	L	L	D	I	R	D	P	S	Q	A	Y	S	A	A	D	F	R	R	D	A	L	A	E	M	A	D	I	T	A	A	G	R	I	P	L	L	V	G	G	T	M	L	Y	F	K	A	L	L	E	G	L	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		P	L	P	S	A	D	P	E	V	R	A	R	I	E	Q	Q	A	A	E	Q	G	W	E	S	L	H	R	Q	L	Q	E	V	D	P	V	A	A	A	R	I	H	P	N	D	P	Q	R	L	S	R	A	L	E	V	F	F	I	S	G	K
Secondary structure
SS confidence
Disorder		?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		T	L	T	E	L	T	Q	T	S	G	D	A	L	P	Y	Q	V	H	Q	F	A	I	A	P	A	S	R	E	L	L	H	Q	R	I	E	Q	R	F	H	Q	M	L	A	S	G	F	E	A	E	V	R	A	L	F	A	R	G	D	L	H
Secondary structure
SS confidence
Disorder								?	?	?	?		?																																																?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		T	D	L	P	S	I	R	C	V	G	Y	R	Q	M	W	S	Y	L	E	G	E	I	S	Y	D	E	M	V	Y	R	G	V	C	A	T	R	Q	L	A	K	R	Q	I	T	W	L	R	G	W	E	G	V	H	W	L	D	S	E	K	P
Secondary structure
SS confidence
Disorder		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.
Sequence		E	Q	A	R	D	E	V	L	Q	V	V	G	A	I	A	G
Secondary structure
SS confidence
Disorder																?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3foz chain B Region: 9 - 311 Aligned: 303 Modelled: 303 Confidence: 100.0% Identity: 100% PDB header:transferase/rna Chain: B: PDB Molecule:trna delta(2)-isopentenylpyrophosphate transferase; PDBTitle: structure of e. coli isopentenyl-trna transferase in complex with e.2 coli trna(phe) Phyre2 PDB 3d3q chain B Region: 10 - 313 Aligned: 299 Modelled: 304 Confidence: 100.0% Identity: 34% PDB header:transferase Chain: B: PDB Molecule:trna delta(2)-isopentenylpyrophosphate PDBTitle: crystal structure of trna delta(2)-isopentenylpyrophosphate2 transferase (se0981) from staphylococcus epidermidis.3 northeast structural genomics consortium target ser100 Phyre2 PDB 3exa chain D Region: 10 - 313 Aligned: 288 Modelled: 291 Confidence: 100.0% Identity: 38% PDB header:transferase Chain: D: PDB Molecule:trna delta(2)-isopentenylpyrophosphate PDBTitle: crystal structure of the full-length trna2 isopentenylpyrophosphate transferase (bh2366) from3 bacillus halodurans, northeast structural genomics4 consortium target bhr41. Phyre2 PDB 3epl chain A Region: 10 - 309 Aligned: 297 Modelled: 300 Confidence: 100.0% Identity: 26% PDB header:transferase/rna Chain: A: PDB Molecule:trna isopentenyltransferase; PDBTitle: crystallographic snapshots of eukaryotic2 dimethylallyltransferase acting on trna: insight into trna3 recognition and reaction mechanism Phyre2 PDB 3crq chain A Region: 8 - 314 Aligned: 232 Modelled: 233 Confidence: 100.0% Identity: 70% PDB header:transferase Chain: A: PDB Molecule:trna delta(2)-isopentenylpyrophosphate PDBTitle: structure of trna dimethylallyltransferase: rna2 modification through a channel Phyre2 PDB 3a8t chain A Region: 10 - 314 Aligned: 238 Modelled: 239 Confidence: 100.0% Identity: 31% PDB header:transferase Chain: A: PDB Molecule:adenylate isopentenyltransferase; PDBTitle: plant adenylate isopentenyltransferase in complex with atp Phyre2 PDB 2ze5 chain A Region: 11 - 231 Aligned: 210 Modelled: 221 Confidence: 100.0% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:isopentenyl transferase; PDBTitle: crystal structure of adenosine phosphate-isopentenyltransferase Phyre2 PDB 1xbt chain A domain 1 Region: 11 - 124 Aligned: 103 Modelled: 114 Confidence: 99.6% Identity: 13% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Type II thymidine kinase Phyre2 PDB 1kgd chain A Region: 8 - 113 Aligned: 86 Modelled: 106 Confidence: 98.6% Identity: 17% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nucleotide and nucleoside kinases Phyre2 PDB 1ukz chain A Region: 3 - 313 Aligned: 193 Modelled: 202 Confidence: 98.5% Identity: 16% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nucleotide and nucleoside kinases Phyre2 PDB 3nwj chain B Region: 11 - 282 Aligned: 173 Modelled: 174 Confidence: 98.5% Identity: 12% PDB header:transferase Chain: B: PDB Molecule:atsk2; PDBTitle: crystal structure of shikimate kinase from arabidopsis thaliana2 (atsk2) Phyre2 PDB 2ia5 chain C Region: 9 - 141 Aligned: 101 Modelled: 102 Confidence: 98.4% Identity: 26% PDB header:transferase Chain: C: PDB Molecule:polynucleotide kinase; PDBTitle: t4 polynucleotide kinase/phosphatase with bound sulfate and2 magnesium. Phyre2 PDB 2qor chain A Region: 7 - 181 Aligned: 157 Modelled: 175 Confidence: 98.4% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:guanylate kinase; PDBTitle: crystal structure of plasmodium vivax guanylate kinase Phyre2 PDB 1kag chain A Region: 10 - 117 Aligned: 89 Modelled: 89 Confidence: 98.4% Identity: 21% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Shikimate kinase (AroK) Phyre2 PDB 1z6g chain A Region: 11 - 151 Aligned: 124 Modelled: 141 Confidence: 98.4% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:guanylate kinase; PDBTitle: crystal structure of guanylate kinase from plasmodium falciparum Phyre2 PDB 1rkb chain A Region: 9 - 314 Aligned: 162 Modelled: 163 Confidence: 98.3% Identity: 28% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nucleotide and nucleoside kinases Phyre2 PDB 3tr0 chain A Region: 8 - 133 Aligned: 108 Modelled: 126 Confidence: 98.3% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:guanylate kinase; PDBTitle: structure of guanylate kinase (gmk) from coxiella burnetii Phyre2 PDB 1lvg chain A Region: 11 - 225 Aligned: 173 Modelled: 184 Confidence: 98.2% Identity: 18% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nucleotide and nucleoside kinases Phyre2 PDB 1sxj chain A Region: 2 - 183 Aligned: 172 Modelled: 182 Confidence: 98.2% Identity: 17% PDB header:replication Chain: A: PDB Molecule:activator 1 95 kda subunit; PDBTitle: crystal structure of the eukaryotic clamp loader2 (replication factor c, rfc) bound to the dna sliding clamp3 (proliferating cell nuclear antigen, pcna) Phyre2 PDB 1s96 chain A Region: 10 - 159 Aligned: 134 Modelled: 150 Confidence: 98.2% Identity: 14% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nucleotide and nucleoside kinases Phyre2 PDB 2bwj chain C Region: 1 - 44 Aligned: 41 Modelled: 41 Confidence: 98.1% Identity: 29% PDB header:transferase Chain: C: PDB Molecule:adenylate kinase 5; PDBTitle: structure of adenylate kinase 5 Phyre2 1 c3fozB_ 2 c3d3qB_ 3 c3exaD_ 4 c3eplA_ 5 c3crqA_ 6 c3a8tA_ 7 c2ze5A_ 8 d1xbta1 9 d1kgda_ 10 d1ukza_ 11 c3nwjB_ 12 c2ia5C_ 13 c2qorA_ 14 d1kaga_ 15 c1z6gA_ 16 d1rkba_ 17 c3tr0A_ 18 d1lvga_ 19 c1sxjA_ 20 d1s96a_ 21 22 23 24 25 c2bwjC_ 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499