Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	D	A	N	K	L	Q	Q	A	V	D	Q	A	Y	T	Q	F	H	S	L	N	G	G	Q	N	A	D	Y	I	P	F	L	A	N	V	P	G	Q	L	A	A	V	A	I	V	T	C	D	G	N	V	Y	S	A	G	D	S	D	Y
Secondary structure
SS confidence
Disorder		?	?	?																			?	?	?		?												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	F	A	L	E	S	I	S	K	V	C	T	L	A	L	A	L	E	D	V	G	P	Q	A	V	Q	D	K	I	G	A	D	P	T	G	L	P	F	N	S	V	I	A	L	E	L	H	G	G	K	P	L	S	P	L	V	N	A	G	A
Secondary structure
SS confidence
Disorder																																														?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		I	A	T	T	S	L	I	N	A	E	N	V	E	Q	R	W	Q	R	I	L	H	I	Q	Q	Q	L	A	G	E	Q	V	A	L	S	D	E	V	N	Q	S	E	Q	T	T	N	F	H	N	R	A	I	A	W	L	L	Y	S	A	G	Y
Secondary structure
SS confidence
Disorder									?	?																																					?														?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	Y	C	D	A	M	E	A	C	D	V	Y	T	R	Q	C	S	T	L	L	N	T	I	E	L	A	T	L	G	A	T	L	A	A	G	G	V	N	P	L	T	H	K	R	V	L	Q	A	D	N	V	P	Y	I	L	A	E	M	M	M
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		E	G	L	Y	G	R	S	G	D	W	A	Y	R	V	G	L	P	G	K	S	G	V	G	G	G	I	L	A	V	V	P	G	V	M	G	I	A	A	F	S	P	P	L	D	E	D	G	N	S	V	R	G	Q	K	M	V	A	S	V	A
Secondary structure
SS confidence
Disorder																			?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310
Sequence		K	Q	L	G	Y	N	V	F	K	G
Secondary structure
SS confidence
Disorder							?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1u60 chain A Region: 2 - 310 Aligned: 309 Modelled: 309 Confidence: 100.0% Identity: 100% Fold: beta-lactamase/transpeptidase-like Superfamily: beta-lactamase/transpeptidase-like Family: Glutaminase Phyre2 PDB 3ih9 chain A Region: 4 - 310 Aligned: 306 Modelled: 307 Confidence: 100.0% Identity: 35% PDB header:hydrolase Chain: A: PDB Molecule:salt-tolerant glutaminase; PDBTitle: crystal structure analysis of mglu in its tris form Phyre2 PDB 2dfw chain A Region: 4 - 310 Aligned: 306 Modelled: 304 Confidence: 100.0% Identity: 34% PDB header:hydrolase Chain: A: PDB Molecule:salt-tolerant glutaminase; PDBTitle: crystal structure of a major fragment of the salt-tolerant2 glutaminase from micrococcus luteus k-3 Phyre2 PDB 3uo9 chain B Region: 3 - 309 Aligned: 300 Modelled: 300 Confidence: 100.0% Identity: 37% PDB header:hydrolase/hydrolase inhibitor Chain: B: PDB Molecule:glutaminase kidney isoform, mitochondrial; PDBTitle: crystal structure of human gac in complex with glutamate and bptes Phyre2 PDB 3czd chain A Region: 3 - 309 Aligned: 302 Modelled: 307 Confidence: 100.0% Identity: 36% PDB header:hydrolase Chain: A: PDB Molecule:glutaminase kidney isoform; PDBTitle: crystal structure of human glutaminase in complex with l-glutamate Phyre2 PDB 2pby chain B Region: 2 - 308 Aligned: 289 Modelled: 292 Confidence: 100.0% Identity: 39% PDB header:hydrolase Chain: B: PDB Molecule:glutaminase; PDBTitle: probable glutaminase from geobacillus kaustophilus hta426 Phyre2 PDB 1mki chain A Region: 26 - 308 Aligned: 282 Modelled: 283 Confidence: 100.0% Identity: 34% Fold: beta-lactamase/transpeptidase-like Superfamily: beta-lactamase/transpeptidase-like Family: Glutaminase Phyre2 PDB 3oc2 chain A Region: 6 - 303 Aligned: 260 Modelled: 267 Confidence: 98.0% Identity: 18% PDB header:penicillin-binding protein Chain: A: PDB Molecule:penicillin-binding protein 3; PDBTitle: crystal structure of penicillin-binding protein 3 from pseudomonas2 aeruginosa Phyre2 PDB 1k25 chain A domain 4 Region: 6 - 242 Aligned: 176 Modelled: 201 Confidence: 97.8% Identity: 21% Fold: beta-lactamase/transpeptidase-like Superfamily: beta-lactamase/transpeptidase-like Family: beta-Lactamase/D-ala carboxypeptidase Phyre2 PDB 3lo7 chain A Region: 6 - 304 Aligned: 256 Modelled: 259 Confidence: 97.8% Identity: 20% PDB header:transferase Chain: A: PDB Molecule:penicillin-binding protein a; PDBTitle: crystal structure of pbpa from mycobacterium tuberculosis Phyre2 PDB 3ue3 chain A Region: 6 - 305 Aligned: 268 Modelled: 286 Confidence: 97.8% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:septum formation, penicillin binding protein 3, PDBTitle: crystal structure of acinetobacter baumanni pbp3 Phyre2 PDB 2wad chain B Region: 4 - 309 Aligned: 276 Modelled: 278 Confidence: 97.7% Identity: 16% PDB header:peptide binding protein Chain: B: PDB Molecule:penicillin-binding protein 2b; PDBTitle: penicillin-binding protein 2b (pbp-2b) from streptococcus2 pneumoniae (strain 5204) Phyre2 PDB 1rp5 chain A domain 4 Region: 6 - 306 Aligned: 267 Modelled: 270 Confidence: 97.7% Identity: 16% Fold: beta-lactamase/transpeptidase-like Superfamily: beta-lactamase/transpeptidase-like Family: beta-Lactamase/D-ala carboxypeptidase Phyre2 PDB 3pbq chain A Region: 6 - 238 Aligned: 198 Modelled: 201 Confidence: 97.6% Identity: 18% PDB header:hydrolase/antibiotic Chain: A: PDB Molecule:penicillin-binding protein 3; PDBTitle: crystal structure of pbp3 complexed with imipenem Phyre2 PDB 3dwk chain C Region: 6 - 279 Aligned: 217 Modelled: 218 Confidence: 97.5% Identity: 15% PDB header:transferase Chain: C: PDB Molecule:penicillin-binding protein 2; PDBTitle: identification of dynamic structural motifs involved in2 peptidoglycan glycosyltransfer Phyre2 PDB 1vqq chain A domain 3 Region: 6 - 303 Aligned: 252 Modelled: 253 Confidence: 97.5% Identity: 17% Fold: beta-lactamase/transpeptidase-like Superfamily: beta-lactamase/transpeptidase-like Family: beta-Lactamase/D-ala carboxypeptidase Phyre2 PDB 1pyy chain A domain 4 Region: 6 - 239 Aligned: 191 Modelled: 202 Confidence: 97.3% Identity: 18% Fold: beta-lactamase/transpeptidase-like Superfamily: beta-lactamase/transpeptidase-like Family: beta-Lactamase/D-ala carboxypeptidase Phyre2 PDB 2olv chain A Region: 6 - 303 Aligned: 248 Modelled: 264 Confidence: 97.2% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:penicillin-binding protein 2; PDBTitle: structural insight into the transglycosylation step of bacterial cell2 wall biosynthesis : donor ligand complex Phyre2 PDB 1n9b chain A Region: 30 - 303 Aligned: 218 Modelled: 233 Confidence: 97.1% Identity: 18% Fold: beta-lactamase/transpeptidase-like Superfamily: beta-lactamase/transpeptidase-like Family: beta-Lactamase/D-ala carboxypeptidase Phyre2 PDB 2c5w chain B domain 1 Region: 58 - 304 Aligned: 216 Modelled: 219 Confidence: 96.9% Identity: 17% Fold: beta-lactamase/transpeptidase-like Superfamily: beta-lactamase/transpeptidase-like Family: beta-Lactamase/D-ala carboxypeptidase Phyre2 1 d1u60a_ 2 c3ih9A_ 3 c2dfwA_ 4 c3uo9B_ 5 c3czdA_ 6 c2pbyB_ 7 d1mkia_ 8 c3oc2A_ 9 d1k25a4 10 c3lo7A_ 11 c3ue3A_ 12 c2wadB_ 13 d1rp5a4 14 c3pbqA_ 15 c3dwkC_ 16 d1vqqa3 17 d1pyya4 18 c2olvA_ 19 d1n9ba_ 20 d2c5wb1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1u60a_ 100.0 100 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:Glutaminase 2 c3ih9A_ 100.0 35 PDB header:hydrolase Chain: A: PDB Molecule:salt-tolerant glutaminase; PDBTitle: crystal structure analysis of mglu in its tris form 3 c2dfwA_ 100.0 34 PDB header:hydrolase Chain: A: PDB Molecule:salt-tolerant glutaminase; PDBTitle: crystal structure of a major fragment of the salt-tolerant2 glutaminase from micrococcus luteus k-3 4 c3uo9B_ 100.0 37 PDB header:hydrolase/hydrolase inhibitor Chain: B: PDB Molecule:glutaminase kidney isoform, mitochondrial; PDBTitle: crystal structure of human gac in complex with glutamate and bptes 5 c3czdA_ 100.0 36 PDB header:hydrolase Chain: A: PDB Molecule:glutaminase kidney isoform; PDBTitle: crystal structure of human glutaminase in complex with l-glutamate 6 c2pbyB_ 100.0 39 PDB header:hydrolase Chain: B: PDB Molecule:glutaminase; PDBTitle: probable glutaminase from geobacillus kaustophilus hta426 7 d1mkia_ 100.0 34 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:Glutaminase 8 c3oc2A_ 98.0 18 PDB header:penicillin-binding protein Chain: A: PDB Molecule:penicillin-binding protein 3; PDBTitle: crystal structure of penicillin-binding protein 3 from pseudomonas2 aeruginosa 9 d1k25a4 97.8 21 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 10 c3lo7A_ 97.8 20 PDB header:transferase Chain: A: PDB Molecule:penicillin-binding protein a; PDBTitle: crystal structure of pbpa from mycobacterium tuberculosis 11 c3ue3A_ 97.8 18 PDB header:transferase Chain: A: PDB Molecule:septum formation, penicillin binding protein 3, PDBTitle: crystal structure of acinetobacter baumanni pbp3 12 c2wadB_ 97.7 16 PDB header:peptide binding protein Chain: B: PDB Molecule:penicillin-binding protein 2b; PDBTitle: penicillin-binding protein 2b (pbp-2b) from streptococcus2 pneumoniae (strain 5204) 13 d1rp5a4 97.7 16 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 14 c3pbqA_ 97.6 18 PDB header:hydrolase/antibiotic Chain: A: PDB Molecule:penicillin-binding protein 3; PDBTitle: crystal structure of pbp3 complexed with imipenem 15 c3dwkC_ 97.5 15 PDB header:transferase Chain: C: PDB Molecule:penicillin-binding protein 2; PDBTitle: identification of dynamic structural motifs involved in2 peptidoglycan glycosyltransfer 16 d1vqqa3 97.5 17 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 17 d1pyya4 97.3 18 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 18 c2olvA_ 97.2 16 PDB header:transferase Chain: A: PDB Molecule:penicillin-binding protein 2; PDBTitle: structural insight into the transglycosylation step of bacterial cell2 wall biosynthesis : donor ligand complex 19 d1n9ba_ 97.1 18 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 20 d2c5wb1 96.9 17 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 21 d2olua2 not modelled 96.8 18 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 22 c1qmfA_ not modelled 96.8 19 PDB header:peptidoglycan synthesis Chain: A: PDB Molecule:penicillin-binding protein 2x; PDBTitle: penicillin-binding protein 2x (pbp-2x) acyl-enzyme complex 23 d1g6aa_ not modelled 96.8 17 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 24 c2jc7A_ not modelled 96.8 9 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase oxa-24; PDBTitle: the crystal structure of the carbapenemase oxa-24 reveals2 new insights into the mechanism of carbapenem-hydrolysis 25 c1pmdA_ not modelled 96.7 16 PDB header:peptidoglycan synthesis Chain: A: PDB Molecule:peptidoglycan synthesis multifunctional enzyme; PDBTitle: penicillin-binding protein 2x (pbp-2x) 26 c2qpnA_ not modelled 96.7 18 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase ges-1; PDBTitle: ges-1 beta-lactamase 27 d1alqa_ not modelled 96.6 22 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 28 d1buea_ not modelled 96.6 18 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 29 c3qhyA_ not modelled 96.4 16 PDB header:hydrolase/hydrolase inhibitor Chain: A: PDB Molecule:beta-lactamase; PDBTitle: structural, thermodynamic and kinetic analysis of the picomolar2 binding affinity interaction of the beta-lactamase inhibitor protein-3 ii (blip-ii) with class a beta-lactamases 30 c2ov5A_ not modelled 96.3 18 PDB header:hydrolase Chain: A: PDB Molecule:carbapenemase; PDBTitle: crystal structure of the kpc-2 carbapenemase 31 c1mwuA_ not modelled 96.3 17 PDB header:biosynthetic protein Chain: A: PDB Molecule:penicillin-binding protein 2a; PDBTitle: structure of methicillin acyl-penicillin binding protein 2a2 from methicillin resistant staphylococcus aureus strain3 27r at 2.60 a resolution. 32 c1w7fB_ not modelled 96.2 17 PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase; PDBTitle: crystal structure of the class a beta-lactamase bs32 inhibited with isocitrate 33 c3equB_ not modelled 96.0 15 PDB header:biosynthetic protein Chain: B: PDB Molecule:penicillin-binding protein 2; PDBTitle: crystal structure of penicillin-binding protein 2 from neisseria2 gonorrhoeae 34 d1nrfa_ not modelled 95.7 15 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 35 c3udiA_ not modelled 95.7 22 PDB header:penicillin-binding protein/antibiotic Chain: A: PDB Molecule:penicillin-binding protein 1a; PDBTitle: crystal structure of acinetobacter baumannii pbp1a in complex with2 penicillin g 36 d1dy6a_ not modelled 95.6 19 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 37 c1i2sA_ not modelled 95.4 16 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase; PDBTitle: beta-lactamase from bacillus licheniformis bs3 38 d1i2sa_ not modelled 95.4 16 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 39 c3cg5A_ not modelled 95.4 16 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase; PDBTitle: crystal structure of the covalent adduct formed between tb2 b-lactamase and clavulanate 40 c2wuqB_ not modelled 95.3 13 PDB header:transcription Chain: B: PDB Molecule:beta-lactamase regulatory protein blab; PDBTitle: crystal structure of blab protein from streptomyces cacaoi 41 d1bsga_ not modelled 95.2 18 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 42 c3lezA_ not modelled 94.9 18 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase; PDBTitle: crystal structure of a halotolerant bacterial beta-lactamase 43 c3fwlA_ not modelled 94.8 22 PDB header:transferase, hydrolase Chain: A: PDB Molecule:penicillin-binding protein 1b; PDBTitle: crystal structure of the full-length transglycosylase pbp1b2 from escherichia coli 44 d2dcfa1 not modelled 94.7 24 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 45 c3p09A_ not modelled 94.7 14 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase; PDBTitle: crystal structure of beta-lactamase from francisella tularensis 46 d1iysa_ not modelled 94.6 20 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 47 c2wuqA_ not modelled 94.5 15 PDB header:transcription Chain: A: PDB Molecule:beta-lactamase regulatory protein blab; PDBTitle: crystal structure of blab protein from streptomyces cacaoi 48 c3i7jB_ not modelled 94.5 29 PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase mb2281c; PDBTitle: crystal structure of a beta-lactamase (mb2281c) from2 mycobacterium bovis, northeast structural genomics3 consortium target mbr246 49 d1e25a_ not modelled 94.2 15 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 50 c3p09B_ not modelled 93.5 15 PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase; PDBTitle: crystal structure of beta-lactamase from francisella tularensis 51 c2iwdA_ not modelled 93.2 14 PDB header:antibiotic resistance Chain: A: PDB Molecule:methicillin resistance mecr1 protein; PDBTitle: oxacilloyl-acylated mecr1 extracellular antibiotic-sensor2 domain. 52 c2wzzA_ not modelled 92.9 32 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase; PDBTitle: amp-c beta-lactamase (pseudomonas aeruginosa)in complex2 with compound m-03 53 c2qmiH_ not modelled 92.8 25 PDB header:hydrolase Chain: H: PDB Molecule:pbp related beta-lactamase; PDBTitle: structure of the octameric penicillin-binding protein2 homologue from pyrococcus abyssi 54 d1djaa_ not modelled 92.6 17 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 55 d1w79a1 not modelled 91.8 25 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:Dac-like 56 d1o7ea_ not modelled 91.3 14 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 57 d2cc1a1 not modelled 90.6 16 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 58 c3ozhA_ not modelled 90.6 21 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase/d-alanine carboxypeptidase; PDBTitle: crystal structure of beta-lactamase/d-alanine carboxypeptidase from2 yersinia pestis 59 d1k55a_ not modelled 90.6 15 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 60 d1w5da1 not modelled 90.2 25 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:Dac-like 61 c3dw0B_ not modelled 89.9 18 PDB header:hydrolase Chain: B: PDB Molecule:class a carbapenemase kpc-2; PDBTitle: crystal structure of the class a carbapenemase kpc-2 at 1.62 angstrom resolution 62 d1xa1a_ not modelled 89.5 13 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 63 d1m6ka_ not modelled 89.0 17 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 64 c2bg1A_ not modelled 88.0 14 PDB header:peptidoglycan Chain: A: PDB Molecule:penicillin-binding protein 1b; PDBTitle: active site restructuring regulates ligand recognition in2 classa penicillin-binding proteins (pbps) 65 d1onha_ not modelled 87.8 25 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 66 c3cjmA_ not modelled 87.7 16 PDB header:hydrolase Chain: A: PDB Molecule:putative beta-lactamase; PDBTitle: crystal structure of putative beta-lactamase (np_815223.1) from2 enterococcus faecalis v583 at 1.50 a resolution 67 c3a3eB_ not modelled 87.1 18 PDB header:hydrolase Chain: B: PDB Molecule:penicillin-binding protein 4; PDBTitle: crystal structure of penicillin binding protein 4 (dacb)2 from haemophilus influenzae, complexed with novel beta-3 lactam (cmv) 68 d2ex2a1 not modelled 86.7 21 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:Dac-like 69 d2bg1a1 not modelled 86.7 14 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 70 c2jciA_ not modelled 86.6 12 PDB header:drug-binding protein Chain: A: PDB Molecule:penicillin-binding protein 1b; PDBTitle: structural insights into the catalytic mechanism and the2 role of streptococcus pneumoniae pbp1b 71 d2hdsa1 not modelled 86.1 25 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 72 c2v20A_ not modelled 86.1 16 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase tem; PDBTitle: structure of a tem-1 beta-lactamase insertant2 allosterically regulated by kanamycin and anions. complex3 with sulfate. 73 d3beca2 not modelled 86.0 20 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 74 c3hleA_ not modelled 85.1 26 PDB header:transferase Chain: A: PDB Molecule:transesterase; PDBTitle: simvastatin synthase (lovd), from aspergillus terreus, s5 mutant, s76a2 mutant, complex with monacolin j acid 75 c3hbrD_ not modelled 85.0 13 PDB header:hydrolase Chain: D: PDB Molecule:oxa-48; PDBTitle: crystal structure of oxa-48 beta-lactamase 76 c1zkjA_ not modelled 84.4 30 PDB header:hydrolase Chain: A: PDB Molecule:extended-spectrum beta-lactamase; PDBTitle: structural basis for the extended substrate spectrum of cmy-2 10, a plasmid-encoded class c beta-lactamase 77 d1ci9a_ not modelled 83.5 29 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 78 d1yqsa1 not modelled 82.7 31 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 79 d2drwa1 not modelled 82.2 20 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 80 c2j7vA_ not modelled 82.0 19 PDB header:hydrolase Chain: A: PDB Molecule:tll2115 protein; PDBTitle: structure of pbp-a 81 d1m40a_ not modelled 81.9 18 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 82 d1ei5a3 not modelled 81.5 31 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 83 c1ei5A_ not modelled 81.2 30 PDB header:hydrolase Chain: A: PDB Molecule:d-aminopeptidase; PDBTitle: crystal structure of a d-aminopeptidase from ochrobactrum2 anthropi 84 c2qz6A_ not modelled 80.8 25 PDB header:hydrolase Chain: A: PDB Molecule:beta-lactamase; PDBTitle: first crystal structure of a psychrophile class c beta-2 lactamase 85 d1rgya_ not modelled 80.4 25 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 86 c1z6fA_ not modelled 80.0 22 PDB header:hydrolase Chain: A: PDB Molecule:penicillin-binding protein 5; PDBTitle: crystal structure of penicillin-binding protein 5 from e. coli in2 complex with a boronic acid inhibitor 87 d1k38a_ not modelled 76.5 17 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 88 d1tvfa2 not modelled 75.2 26 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 89 d1hzoa_ not modelled 75.0 25 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 90 c3o3vB_ not modelled 74.9 23 PDB header:hydrolase Chain: B: PDB Molecule:beta-lactamase; PDBTitle: crystal structure of clbp peptidase domain 91 c2bcfA_ not modelled 69.6 21 PDB header:hydrolase Chain: A: PDB Molecule:probable d-alanyl-d-alanine carboxypeptidase PDBTitle: crystal structure of a evolved putative penicillin-binding2 protein homolog, rv2911, from mycobacterium tuberculosis. 92 c1tvfA_ not modelled 68.6 26 PDB header:penicillin binding Chain: A: PDB Molecule:penicillin binding protein 4; PDBTitle: crystal structure of penicillin-binding protein 4 (pbp4)2 from staphylococcus aureus 93 d1xp4a2 not modelled 65.1 26 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 94 c3it9B_ not modelled 63.3 18 PDB header:hydrolase Chain: B: PDB Molecule:d-alanyl-d-alanine carboxypeptidase dacc; PDBTitle: crystal structure of penicillin-binding protein 6 (pbp6)2 from e. coli in apo state 95 c3a3jA_ not modelled 61.8 27 PDB header:hydrolase Chain: A: PDB Molecule:pbp5; PDBTitle: crystal structures of penicillin binding protein 5 from2 haemophilus influenzae 96 c3humB_ not modelled 60.5 26 PDB header:hydrolase/antibiotics Chain: B: PDB Molecule:penicillin-binding protein 4; PDBTitle: crystal structure of penicillin binding protein 4 from2 staphylococcus aureus col in complex with cefotaxime 97 d1es5a_ not modelled 58.3 21 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:beta-Lactamase/D-ala carboxypeptidase 98 c3if6C_ not modelled 53.1 11 PDB header:hydrolase Chain: C: PDB Molecule:oxa-46 oxacillinase; PDBTitle: crystal structure of oxa-46 beta-lactamase from p.2 aeruginosa 99 c2xftA_ not modelled 52.6 13 PDB header:hydrolase Chain: A: PDB Molecule:orf12; PDBTitle: structural and mechanistic studies on a cephalosporin esterase from2 the clavulanic acid biosynthesis pathway 100 c3tg9A_ not modelled 50.0 21 PDB header:penicillin binding protein Chain: A: PDB Molecule:penicillin-binding protein; PDBTitle: the crystal structure of penicillin binding protein from bacillus2 halodurans 101 c3mfdB_ not modelled 42.7 31 PDB header:hydrolase Chain: B: PDB Molecule:d-alanyl-d-alanine carboxypeptidase dacb; PDBTitle: the structure of the beta-lactamase superfamily domain of d-alanyl-d-2 alanine carboxypeptidase from bacillus subtilis 102 c1xp4C_ not modelled 41.0 26 PDB header:hydrolase Chain: C: PDB Molecule:d-alanyl-d-alanine carboxypeptidase; PDBTitle: crystal structure of a peptidoglycan synthesis regulatory2 factor (pbp3) from streptococcus pneumoniae 103 d1t6aa_ not modelled 38.3 26 Fold:TBP-like Superfamily:Rbstp2229 protein Family:Rbstp2229 protein 104 c2cblA_ not modelled 36.8 24 PDB header:complex (proto-oncogene/peptide) Chain: A: PDB Molecule:proto-oncogene cbl; PDBTitle: n-terminal domain of cbl in complex with its binding site2 on zap-70 105 c2oa6B_ not modelled 36.6 11 PDB header:lyase Chain: B: PDB Molecule:aristolochene synthase; PDBTitle: aristolochene synthase from aspergillus terreus complexed with2 pyrophosphate 106 c3bunB_ not modelled 36.2 24 PDB header:ligase/signaling protein Chain: B: PDB Molecule:e3 ubiquitin-protein ligase cbl; PDBTitle: crystal structure of c-cbl-tkb domain complexed with its2 binding motif in sprouty4 107 c3ik5A_ not modelled 29.1 15 PDB header:viral protein/signaling protein Chain: A: PDB Molecule:protein nef; PDBTitle: sivmac239 nef in complex with tcr zeta itam 1 polypeptide2 (a63-r80) 108 d1efnb_ not modelled 27.4 15 Fold:Regulatory factor Nef Superfamily:Regulatory factor Nef Family:Regulatory factor Nef 109 d1di1a_ not modelled 27.2 9 Fold:Terpenoid synthases Superfamily:Terpenoid synthases Family:Aristolochene/pentalenene synthase 110 d2nefa_ not modelled 26.3 15 Fold:Regulatory factor Nef Superfamily:Regulatory factor Nef Family:Regulatory factor Nef 111 c2xi1A_ not modelled 25.5 19 PDB header:viral protein Chain: A: PDB Molecule:nef; PDBTitle: crystal structure of the hiv-1 nef sequenced from a patient's sample 112 d1sf9a_ not modelled 25.3 9 Fold:SH3-like barrel Superfamily:Hypothetical protein YfhH Family:Hypothetical protein YfhH 113 d3buxb3 not modelled 24.5 21 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 114 d1chka_ not modelled 21.7 21 Fold:Lysozyme-like Superfamily:Lysozyme-like Family:Chitosanase

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0