Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	K	N	R	A	F	L	K	W	A	G	G	K	Y	P	L	L	D	D	I	K	R	H	L	P	K	G	E	C	L	V	E	P	F	V	G	A	G	S	V	F	L	N	T	D	F	S	R	Y	I	L	A	D	I	N	S	D	L	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	L	Y	N	I	V	K	M	R	T	D	E	Y	V	Q	A	A	R	E	L	F	V	P	E	T	N	C	A	E	V	Y	Y	Q	F	R	E	E	F	N	K	S	Q	D	P	F	R	R	A	V	L	F	L	Y	L	N	R	Y	G	Y	N
Secondary structure
SS confidence
Disorder																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	L	C	R	Y	N	L	R	G	E	F	N	V	P	F	G	R	Y	K	K	P	Y	F	P	E	A	E	L	Y	H	F	A	E	K	A	Q	N	A	F	F	Y	C	E	S	Y	A	D	S	M	A	R	A	D	D	A	S	V	V	Y	C
Secondary structure
SS confidence
Disorder							?	?	?	?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		D	P	P	Y	A	P	L	S	A	T	A	N	F	T	A	Y	H	T	N	S	F	T	L	E	Q	Q	A	H	L	A	E	I	A	E	G	L	V	E	R	H	I	P	V	L	I	S	N	H	D	T	M	L	T	R	E	W	Y	Q	R	A
Secondary structure
SS confidence
Disorder					?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.
Sequence		K	L	H	V	V	K	V	R	R	S	I	S	S	N	G	G	T	R	K	K	V	D	E	L	L	A	L	Y	K	P	G	V	V	S	P	A	K	K
Secondary structure
SS confidence
Disorder													?	?	?	?	?	?	?	?													?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2g1p chain B Region: 3 - 270 Aligned: 246 Modelled: 258 Confidence: 100.0% Identity: 100% PDB header:transferase/dna Chain: B: PDB Molecule:dna adenine methylase; PDBTitle: structure of e. coli dna adenine methyltransferase (dam) Phyre2 PDB 2dpm chain A Region: 3 - 269 Aligned: 249 Modelled: 256 Confidence: 100.0% Identity: 31% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: N6 adenine-specific DNA methylase, DAM Phyre2 PDB 1yf3 chain A domain 1 Region: 4 - 268 Aligned: 252 Modelled: 265 Confidence: 100.0% Identity: 24% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: N6 adenine-specific DNA methylase, DAM Phyre2 PDB 3egi chain A Region: 16 - 249 Aligned: 145 Modelled: 152 Confidence: 97.4% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:trimethylguanosine synthase homolog; PDBTitle: methyltransferase domain of human trimethylguanosine2 synthase tgs1 bound to m7gpppa (inactive form) Phyre2 PDB 2b78 chain A Region: 15 - 237 Aligned: 128 Modelled: 140 Confidence: 97.3% Identity: 19% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein smu.776; PDBTitle: a putative sam-dependent methyltransferase from2 streptococcus mutans Phyre2 PDB 3bt7 chain A Region: 15 - 246 Aligned: 128 Modelled: 128 Confidence: 97.2% Identity: 18% PDB header:transferase/rna Chain: A: PDB Molecule:trna (uracil-5-)-methyltransferase; PDBTitle: structure of e. coli 5-methyluridine methyltransferase trma2 in complex with 19 nucleotide t-arm analogue Phyre2 PDB 3gdh chain C Region: 15 - 268 Aligned: 163 Modelled: 172 Confidence: 97.2% Identity: 18% PDB header:transferase Chain: C: PDB Molecule:trimethylguanosine synthase homolog; PDBTitle: methyltransferase domain of human trimethylguanosine2 synthase 1 (tgs1) bound to m7gtp and adenosyl-homocysteine3 (active form) Phyre2 PDB 2as0 chain A domain 2 Region: 15 - 237 Aligned: 134 Modelled: 139 Confidence: 97.1% Identity: 15% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: hypothetical RNA methyltransferase Phyre2 PDB 2b78 chain A domain 2 Region: 15 - 237 Aligned: 130 Modelled: 142 Confidence: 97.1% Identity: 15% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: hypothetical RNA methyltransferase Phyre2 PDB 1boo chain A Region: 156 - 224 Aligned: 68 Modelled: 69 Confidence: 97.0% Identity: 13% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: Type II DNA methylase Phyre2 PDB 3c0k chain B Region: 16 - 226 Aligned: 123 Modelled: 130 Confidence: 96.9% Identity: 20% PDB header:transferase Chain: B: PDB Molecule:upf0064 protein yccw; PDBTitle: crystal structure of a ribosomal rna methyltranferase Phyre2 PDB 3q87 chain B Region: 17 - 249 Aligned: 134 Modelled: 141 Confidence: 96.8% Identity: 14% PDB header:transferase activator/transferase Chain: B: PDB Molecule:n6 adenine specific dna methylase; PDBTitle: structure of eukaryotic translation termination complex2 methyltransferase mtq2-trm112 Phyre2 PDB 1g60 chain A Region: 155 - 224 Aligned: 69 Modelled: 70 Confidence: 96.7% Identity: 14% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: Type II DNA methylase Phyre2 PDB 3ll7 chain A Region: 13 - 277 Aligned: 164 Modelled: 184 Confidence: 96.7% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:putative methyltransferase; PDBTitle: crystal structure of putative methyltransferase pg_1098 from2 porphyromonas gingivalis w83 Phyre2 PDB 1uwv chain A Region: 15 - 236 Aligned: 119 Modelled: 119 Confidence: 96.5% Identity: 25% PDB header:transferase Chain: A: PDB Molecule:23s rrna (uracil-5-)-methyltransferase ruma; PDBTitle: crystal structure of ruma, the iron-sulfur cluster2 containing e. coli 23s ribosomal rna 5-methyluridine3 methyltransferase Phyre2 PDB 2as0 chain A Region: 15 - 237 Aligned: 134 Modelled: 139 Confidence: 96.4% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:hypothetical protein ph1915; PDBTitle: crystal structure of ph1915 (apc 5817): a hypothetical rna2 methyltransferase Phyre2 PDB 1nw6 chain A Region: 16 - 64 Aligned: 49 Modelled: 49 Confidence: 96.3% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:modification methylase rsri; PDBTitle: structure of the beta class n6-adenine dna methyltransferase rsri2 bound to sinefungin Phyre2 PDB 2vs1 chain A Region: 15 - 236 Aligned: 116 Modelled: 121 Confidence: 96.0% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:uncharacterized rna methyltransferase pyrab10780; PDBTitle: the crystal structure of pyrococcus abyssi trna (uracil-54,2 c5)-methyltransferase in complex with s-adenosyl-l-3 homocysteine Phyre2 PDB 1eg2 chain A Region: 16 - 68 Aligned: 53 Modelled: 53 Confidence: 96.0% Identity: 17% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: Type II DNA methylase Phyre2 PDB 2zif chain B Region: 159 - 229 Aligned: 65 Modelled: 71 Confidence: 95.9% Identity: 18% PDB header:transferase Chain: B: PDB Molecule:putative modification methylase; PDBTitle: crystal structure of ttha0409, putative dna modification2 methylase from thermus thermophilus hb8- complexed with s-3 adenosyl-l-methionine Phyre2 1 c2g1pB_ 2 d2dpma_ 3 d1yf3a1 4 c3egiA_ 5 c2b78A_ 6 c3bt7A_ 7 c3gdhC_ 8 d2as0a2 9 d2b78a2 10 d1booa_ 11 c3c0kB_ 12 c3q87B_ 13 d1g60a_ 14 c3ll7A_ 15 c1uwvA_ 16 c2as0A_ 17 c1nw6A_ 18 c2vs1A_ 19 d1eg2a_ 20 c2zifB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2g1pB_ 100.0 100 PDB header:transferase/dna Chain: B: PDB Molecule:dna adenine methylase; PDBTitle: structure of e. coli dna adenine methyltransferase (dam) 2 d2dpma_ 100.0 31 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:N6 adenine-specific DNA methylase, DAM 3 d1yf3a1 100.0 24 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:N6 adenine-specific DNA methylase, DAM 4 c3egiA_ 97.4 21 PDB header:transferase Chain: A: PDB Molecule:trimethylguanosine synthase homolog; PDBTitle: methyltransferase domain of human trimethylguanosine2 synthase tgs1 bound to m7gpppa (inactive form) 5 c2b78A_ 97.3 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein smu.776; PDBTitle: a putative sam-dependent methyltransferase from2 streptococcus mutans 6 c3bt7A_ 97.2 18 PDB header:transferase/rna Chain: A: PDB Molecule:trna (uracil-5-)-methyltransferase; PDBTitle: structure of e. coli 5-methyluridine methyltransferase trma2 in complex with 19 nucleotide t-arm analogue 7 c3gdhC_ 97.2 18 PDB header:transferase Chain: C: PDB Molecule:trimethylguanosine synthase homolog; PDBTitle: methyltransferase domain of human trimethylguanosine2 synthase 1 (tgs1) bound to m7gtp and adenosyl-homocysteine3 (active form) 8 d2as0a2 97.1 15 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:hypothetical RNA methyltransferase 9 d2b78a2 97.1 15 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:hypothetical RNA methyltransferase 10 d1booa_ 97.0 13 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Type II DNA methylase 11 c3c0kB_ 96.9 20 PDB header:transferase Chain: B: PDB Molecule:upf0064 protein yccw; PDBTitle: crystal structure of a ribosomal rna methyltranferase 12 c3q87B_ 96.8 14 PDB header:transferase activator/transferase Chain: B: PDB Molecule:n6 adenine specific dna methylase; PDBTitle: structure of eukaryotic translation termination complex2 methyltransferase mtq2-trm112 13 d1g60a_ 96.7 14 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Type II DNA methylase 14 c3ll7A_ 96.7 13 PDB header:transferase Chain: A: PDB Molecule:putative methyltransferase; PDBTitle: crystal structure of putative methyltransferase pg_1098 from2 porphyromonas gingivalis w83 15 c1uwvA_ 96.5 25 PDB header:transferase Chain: A: PDB Molecule:23s rrna (uracil-5-)-methyltransferase ruma; PDBTitle: crystal structure of ruma, the iron-sulfur cluster2 containing e. coli 23s ribosomal rna 5-methyluridine3 methyltransferase 16 c2as0A_ 96.4 15 PDB header:transferase Chain: A: PDB Molecule:hypothetical protein ph1915; PDBTitle: crystal structure of ph1915 (apc 5817): a hypothetical rna2 methyltransferase 17 c1nw6A_ 96.3 18 PDB header:transferase Chain: A: PDB Molecule:modification methylase rsri; PDBTitle: structure of the beta class n6-adenine dna methyltransferase rsri2 bound to sinefungin 18 c2vs1A_ 96.0 18 PDB header:transferase Chain: A: PDB Molecule:uncharacterized rna methyltransferase pyrab10780; PDBTitle: the crystal structure of pyrococcus abyssi trna (uracil-54,2 c5)-methyltransferase in complex with s-adenosyl-l-3 homocysteine 19 d1eg2a_ 96.0 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Type II DNA methylase 20 c2zifB_ 95.9 18 PDB header:transferase Chain: B: PDB Molecule:putative modification methylase; PDBTitle: crystal structure of ttha0409, putative dna modification2 methylase from thermus thermophilus hb8- complexed with s-3 adenosyl-l-methionine 21 d2oyra1 not modelled 95.6 14 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:YhiQ-like 22 d1ws6a1 not modelled 95.6 20 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:YhhF-like 23 d2pkwa1 not modelled 95.0 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:YhiQ-like 24 c3fydA_ not modelled 94.9 21 PDB header:transferase Chain: A: PDB Molecule:probable dimethyladenosine transferase; PDBTitle: crystal structure of dim1 from the thermophilic archeon,2 methanocaldococcus jannaschi 25 c3grrA_ not modelled 94.6 21 PDB header:transferase Chain: A: PDB Molecule:dimethyladenosine transferase; PDBTitle: crystal structure of the complex between s-adenosyl homocysteine and2 methanocaldococcus jannaschi dim1. 26 c2yx1A_ not modelled 94.6 20 PDB header:transferase Chain: A: PDB Molecule:hypothetical protein mj0883; PDBTitle: crystal structure of m.jannaschii trna m1g37 methyltransferase 27 c1wxwA_ not modelled 94.5 15 PDB header:transferase Chain: A: PDB Molecule:hypothetical protein ttha1280; PDBTitle: crystal structure of tt1595, a putative sam-dependent2 methyltransferase from thermus thermophillus hb8 28 c3a27A_ not modelled 94.4 14 PDB header:transferase Chain: A: PDB Molecule:uncharacterized protein mj1557; PDBTitle: crystal structure of m. jannaschii tyw2 in complex with2 adomet 29 c3p9nA_ not modelled 93.8 10 PDB header:transferase Chain: A: PDB Molecule:possible methyltransferase (methylase); PDBTitle: rv2966c of m. tuberculosis is a rsmd-like methyltransferase 30 d2fpoa1 not modelled 93.7 12 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:YhhF-like 31 d2fhpa1 not modelled 93.5 13 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:YhhF-like 32 d1wxxa2 not modelled 93.5 14 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:hypothetical RNA methyltransferase 33 c3lduA_ not modelled 93.3 29 PDB header:transferase Chain: A: PDB Molecule:putative methylase; PDBTitle: the crystal structure of a possible methylase from2 clostridium difficile 630. 34 c3dmgA_ not modelled 93.2 19 PDB header:transferase Chain: A: PDB Molecule:probable ribosomal rna small subunit methyltransferase; PDBTitle: t. thermophilus 16s rrna n2 g1207 methyltransferase (rsmc) in complex2 with adohcy 35 d2ifta1 not modelled 93.1 13 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:YhhF-like 36 c3ldgA_ not modelled 93.0 19 PDB header:transferase Chain: A: PDB Molecule:putative uncharacterized protein smu.472; PDBTitle: crystal structure of smu.472, a putative methyltransferase complexed2 with sah 37 d2frna1 not modelled 92.9 13 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Met-10+ protein-like 38 c2esrB_ not modelled 92.7 15 PDB header:transferase Chain: B: PDB Molecule:methyltransferase; PDBTitle: conserved hypothetical protein- streptococcus pyogenes 39 c3axtA_ not modelled 92.7 19 PDB header:transferase Chain: A: PDB Molecule:probable n(2),n(2)-dimethylguanosine trna methyltransferase PDBTitle: complex structure of trna methyltransferase trm1 from aquifex aeolicus2 with s-adenosyl-l-methionine 40 c3k0bA_ not modelled 92.6 23 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:predicted n6-adenine-specific dna methylase; PDBTitle: crystal structure of a predicted n6-adenine-specific dna methylase2 from listeria monocytogenes str. 4b f2365 41 d2esra1 not modelled 92.5 15 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:YhhF-like 42 c2r6zA_ not modelled 91.6 17 PDB header:transferase Chain: A: PDB Molecule:upf0341 protein in rsp 3' region; PDBTitle: crystal structure of the sam-dependent methyltransferase2 ngo1261 from neisseria gonorrhoeae, northeast structural3 genomics consortium target ngr48 43 d2b3ta1 not modelled 91.3 22 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:N5-glutamine methyltransferase, HemK 44 c3a26A_ not modelled 90.7 13 PDB header:transferase Chain: A: PDB Molecule:uncharacterized protein ph0793; PDBTitle: crystal structure of p. horikoshii tyw2 in complex with2 mesado 45 d1uwva2 not modelled 90.3 14 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:(Uracil-5-)-methyltransferase 46 d2ar0a1 not modelled 89.6 24 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:N-6 DNA Methylase-like 47 d2igta1 not modelled 89.3 11 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:hypothetical RNA methyltransferase 48 d2dula1 not modelled 88.8 18 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:TRM1-like 49 c1g38A_ not modelled 88.7 18 PDB header:transferase/dna Chain: A: PDB Molecule:modification methylase taqi; PDBTitle: adenine-specific methyltransferase m. taq i/dna complex 50 c3lkdB_ not modelled 88.4 24 PDB header:transferase Chain: B: PDB Molecule:type i restriction-modification system PDBTitle: crystal structure of the type i restriction-modification2 system methyltransferase subunit from streptococcus3 thermophilus, northeast structural genomics consortium4 target sur80 51 c1aqjB_ not modelled 88.2 19 PDB header:methyltransferase Chain: B: PDB Molecule:adenine-n6-dna-methyltransferase taqi; PDBTitle: structure of adenine-n6-dna-methyltransferase taqi 52 c3s1sA_ not modelled 88.2 25 PDB header:hydrolase, transferase Chain: A: PDB Molecule:restriction endonuclease bpusi; PDBTitle: characterization and crystal structure of the type iig restriction2 endonuclease bpusi 53 d1nv8a_ not modelled 87.7 10 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:N5-glutamine methyltransferase, HemK 54 c1wg8B_ not modelled 87.7 17 PDB header:transferase Chain: B: PDB Molecule:predicted s-adenosylmethionine-dependent PDBTitle: crystal structure of a predicted s-adenosylmethionine-2 dependent methyltransferase tt1512 from thermus3 thermophilus hb8. 55 d1wy7a1 not modelled 87.7 11 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Ta1320-like 56 c3gnlB_ not modelled 86.9 11 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein, duf633, lmof2365_1472; PDBTitle: structure of uncharacterized protein (lmof2365_1472) from2 listeria monocytogenes serotype 4b 57 c3me5A_ not modelled 86.8 14 PDB header:transferase Chain: A: PDB Molecule:cytosine-specific methyltransferase; PDBTitle: crystal structure of putative dna cytosine methylase from shigella2 flexneri 2a str. 301 58 c3tqsB_ not modelled 86.4 30 PDB header:transferase Chain: B: PDB Molecule:ribosomal rna small subunit methyltransferase a; PDBTitle: structure of the dimethyladenosine transferase (ksga) from coxiella2 burnetii 59 c3khkA_ not modelled 86.4 22 PDB header:dna binding protein Chain: A: PDB Molecule:type i restriction-modification system PDBTitle: crystal structure of type-i restriction-modification system2 methylation subunit (mm_0429) from methanosarchina mazei. 60 c3lecA_ not modelled 86.1 17 PDB header:structure genomics, unknown function Chain: A: PDB Molecule:nadb-rossmann superfamily protein; PDBTitle: the crystal structure of a protein in the nadb-rossmann2 superfamily from streptococcus agalactiae to 1.8a 61 d2okca1 not modelled 85.7 24 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:N-6 DNA Methylase-like 62 c3l8dA_ not modelled 85.4 15 PDB header:transferase Chain: A: PDB Molecule:methyltransferase; PDBTitle: crystal structure of methyltransferase from bacillus2 thuringiensis 63 c3mtiA_ not modelled 84.7 16 PDB header:transferase Chain: A: PDB Molecule:rrna methylase; PDBTitle: the crystal structure of a rrna methylase from streptococcus2 thermophilus to 1.95a 64 d2f8la1 not modelled 84.2 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:N-6 DNA Methylase-like 65 d2c7pa1 not modelled 84.2 14 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:C5 cytosine-specific DNA methylase, DCM 66 c1m6yA_ not modelled 83.8 19 PDB header:transferase Chain: A: PDB Molecule:s-adenosyl-methyltransferase mraw; PDBTitle: crystal structure analysis of tm0872, a putative sam-2 dependent methyltransferase, complexed with sah 67 d1qyra_ not modelled 83.6 20 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:rRNA adenine dimethylase-like 68 d1dcta_ not modelled 83.3 22 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:C5 cytosine-specific DNA methylase, DCM 69 d2oo3a1 not modelled 83.2 8 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:LPG1296-like 70 d1g55a_ not modelled 82.2 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:C5 cytosine-specific DNA methylase, DCM 71 d2ih2a1 not modelled 82.1 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:DNA methylase TaqI, N-terminal domain 72 c3grzA_ not modelled 81.5 14 PDB header:transferase Chain: A: PDB Molecule:ribosomal protein l11 methyltransferase; PDBTitle: crystal structure of ribosomal protein l11 methylase from2 lactobacillus delbrueckii subsp. bulgaricus 73 c3ku1E_ not modelled 80.7 11 PDB header:transferase Chain: E: PDB Molecule:sam-dependent methyltransferase; PDBTitle: crystal structure of streptococcus pneumoniae sp1610, a2 putative trna (m1a22) methyltransferase, in complex with s-3 adenosyl-l-methionine 74 d1qama_ not modelled 80.7 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:rRNA adenine dimethylase-like 75 c3g7uA_ not modelled 80.6 22 PDB header:transferase Chain: A: PDB Molecule:cytosine-specific methyltransferase; PDBTitle: crystal structure of putative dna modification methyltransferase2 encoded within prophage cp-933r (e.coli) 76 c3fuxB_ not modelled 80.3 16 PDB header:transferase Chain: B: PDB Molecule:dimethyladenosine transferase; PDBTitle: t. thermophilus 16s rrna a1518 and a1519 methyltransferase (ksga) in2 complex with 5'-methylthioadenosine in space group p212121 77 d1l3ia_ not modelled 79.2 25 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Precorrin-6Y methyltransferase (CbiT) 78 d1zq9a1 not modelled 78.8 13 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:rRNA adenine dimethylase-like 79 c2qrvA_ not modelled 78.5 22 PDB header:transferase/transferase regulator Chain: A: PDB Molecule:dna (cytosine-5)-methyltransferase 3a; PDBTitle: structure of dnmt3a-dnmt3l c-terminal domain complex 80 d1wg8a2 not modelled 78.4 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:MraW-like putative methyltransferases 81 d2nxca1 not modelled 78.4 18 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Ribosomal protein L11 methyltransferase PrmA 82 c2e58D_ not modelled 78.2 18 PDB header:transferase Chain: D: PDB Molecule:mnmc2; PDBTitle: crystal structure of mnmc2 from aquifex aeolicus 83 c2h1rA_ not modelled 78.0 28 PDB header:transferase Chain: A: PDB Molecule:dimethyladenosine transferase, putative; PDBTitle: crystal structure of a dimethyladenosine transferase from2 plasmodium falciparum 84 c3lx6B_ not modelled 76.5 14 PDB header:transferase Chain: B: PDB Molecule:cytosine-specific methyltransferase; PDBTitle: structure of probable cytosine-specific methyltransferase from2 shigella flexneri 85 c3av6A_ not modelled 76.0 8 PDB header:transferase Chain: A: PDB Molecule:dna (cytosine-5)-methyltransferase 1; PDBTitle: crystal structure of mouse dna methyltransferase 1 with adomet 86 c3pt9A_ not modelled 75.2 8 PDB header:transferase Chain: A: PDB Molecule:dna (cytosine-5)-methyltransferase 1; PDBTitle: crystal structure of mouse dnmt1(731-1602) in the free state 87 c3pt6B_ not modelled 73.8 8 PDB header:transferase/dna Chain: B: PDB Molecule:dna (cytosine-5)-methyltransferase 1; PDBTitle: crystal structure of mouse dnmt1(650-1602) in complex with dna 88 d1o9ga_ not modelled 73.0 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:rRNA methyltransferase AviRa 89 c3njrB_ not modelled 72.9 29 PDB header:transferase Chain: B: PDB Molecule:precorrin-6y methylase; PDBTitle: crystal structure of c-terminal domain of precorrin-6y c5,15-2 methyltransferase from rhodobacter capsulatus 90 d1ne2a_ not modelled 72.4 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Ta1320-like 91 c3fteA_ not modelled 72.2 22 PDB header:transferase/rna Chain: A: PDB Molecule:dimethyladenosine transferase; PDBTitle: crystal structure of a. aeolicus ksga in complex with rna 92 c3evzA_ not modelled 72.2 13 PDB header:transferase Chain: A: PDB Molecule:methyltransferase; PDBTitle: crystal strucure of methyltransferase from pyrococcus furiosus 93 c3swrA_ not modelled 71.9 8 PDB header:transferase Chain: A: PDB Molecule:dna (cytosine-5)-methyltransferase 1; PDBTitle: structure of human dnmt1 (601-1600) in complex with sinefungin 94 c2pjdA_ not modelled 71.6 13 PDB header:transferase Chain: A: PDB Molecule:ribosomal rna small subunit methyltransferase c; PDBTitle: crystal structure of 16s rrna methyltransferase rsmc 95 c2qm3A_ not modelled 71.4 22 PDB header:transferase Chain: A: PDB Molecule:predicted methyltransferase; PDBTitle: crystal structure of a predicted methyltransferase from pyrococcus2 furiosus 96 c2yxdA_ not modelled 70.8 18 PDB header:transferase Chain: A: PDB Molecule:probable cobalt-precorrin-6y c(15)-methyltransferase PDBTitle: crystal structure of cobalamin biosynthesis precorrin 8w decarboxylase2 (cbit) 97 d1dusa_ not modelled 67.3 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Hypothetical protein MJ0882 98 c3bxoA_ not modelled 66.1 13 PDB header:transferase Chain: A: PDB Molecule:n,n-dimethyltransferase; PDBTitle: crystal structure of streptomyces venezuelae desvi 99 c3e05B_ not modelled 65.6 15 PDB header:transferase Chain: B: PDB Molecule:precorrin-6y c5,15-methyltransferase (decarboxylating); PDBTitle: crystal structure of precorrin-6y c5,15-methyltransferase from2 geobacter metallireducens gs-15 100 c3hm2G_ not modelled 64.5 16 PDB header:transferase Chain: G: PDB Molecule:precorrin-6y c5,15-methyltransferase; PDBTitle: crystal structure of putative precorrin-6y c5,15-2 methyltransferase targeted domain from corynebacterium3 diphtheriae 101 c2ozvA_ not modelled 64.3 8 PDB header:transferase Chain: A: PDB Molecule:hypothetical protein atu0636; PDBTitle: crystal structure of a predicted o-methyltransferase, protein atu6362 from agrobacterium tumefaciens. 102 d1sqga2 not modelled 64.1 10 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:NOL1/NOP2/sun 103 c3pfhD_ not modelled 62.8 22 PDB header:transferase Chain: D: PDB Molecule:n-methyltransferase; PDBTitle: x-ray crystal structure the n,n-dimethyltransferase tylm1 from2 streptomyces fradiae in complex with sah and dtdp-quip3n 104 c3c6kC_ not modelled 62.2 11 PDB header:transferase Chain: C: PDB Molecule:spermine synthase; PDBTitle: crystal structure of human spermine synthase in complex2 with spermidine and 5-methylthioadenosine 105 c3uzuA_ not modelled 61.4 28 PDB header:transferase Chain: A: PDB Molecule:ribosomal rna small subunit methyltransferase a; PDBTitle: the structure of the ribosomal rna small subunit methyltransferase a2 from burkholderia pseudomallei 106 c3lpmA_ not modelled 58.4 16 PDB header:transferase Chain: A: PDB Molecule:putative methyltransferase; PDBTitle: crystal structure of putative methyltransferase small domain protein2 from listeria monocytogenes 107 d2bzga1 not modelled 58.0 14 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Thiopurine S-methyltransferase 108 d1xvaa_ not modelled 57.2 10 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Glycine N-methyltransferase 109 c3cc8A_ not modelled 55.5 7 PDB header:transferase Chain: A: PDB Molecule:putative methyltransferase; PDBTitle: crystal structure of a putative methyltransferase (bce_1332) from2 bacillus cereus atcc 10987 at 1.64 a resolution 110 c3g2qA_ not modelled 55.5 7 PDB header:transferase Chain: A: PDB Molecule:pcza361.24; PDBTitle: crystal structure of the glycopeptide n-methyltransferase mtfa2 complexed with sinefungin 111 c1qhoA_ not modelled 55.0 10 PDB header:hydrolase Chain: A: PDB Molecule:alpha-amylase; PDBTitle: five-domain alpha-amylase from bacillus stearothermophilus,2 maltose/acarbose complex 112 c3sm3A_ not modelled 54.4 23 PDB header:transferase Chain: A: PDB Molecule:sam-dependent methyltransferases; PDBTitle: crystal structure of sam-dependent methyltransferases q8puk2_metma2 from methanosarcina mazei. northeast structural genomics consortium3 target mar262. 113 c2yvlB_ not modelled 53.5 13 PDB header:transferase Chain: B: PDB Molecule:hypothetical protein; PDBTitle: crystal structure of trna (m1a58) methyltransferase trmi from aquifex2 aeolicus 114 d1qhoa4 not modelled 52.8 10 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 115 c3cggB_ not modelled 51.7 19 PDB header:transferase Chain: B: PDB Molecule:sam-dependent methyltransferase; PDBTitle: crystal structure of tehb-like sam-dependent methyltransferase2 (np_600671.1) from corynebacterium glutamicum atcc 13032 kitasato at3 2.00 a resolution 116 c3lcvB_ not modelled 51.6 22 PDB header:transferase Chain: B: PDB Molecule:sisomicin-gentamicin resistance methylase sgm; PDBTitle: crystal structure of antibiotic related methyltransferase 117 c3bgvC_ not modelled 50.9 13 PDB header:transferase Chain: C: PDB Molecule:mrna cap guanine-n7 methyltransferase; PDBTitle: crystal structure of mrna cap guanine-n7 methyltransferase2 in complex with sah 118 c3eeyJ_ not modelled 50.0 22 PDB header:transferase Chain: J: PDB Molecule:putative rrna methylase; PDBTitle: crystal structure of putative rrna-methylase from clostridium2 thermocellum 119 d1r74a_ not modelled 47.8 12 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Glycine N-methyltransferase 120 d1m6ya2 not modelled 44.5 18 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:MraW-like putative methyltransferases

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0