Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP39364
DateThu Jan 5 11:59:55 GMT 2012
Unique Job ID55090a1ebc5d3945

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2ekcA_
Top template information
PDB header:lyase
Chain: A: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5
Confidence and coverage
Confidence:100.0% Coverage: 89%
238 residues ( 89% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MSWLKEVIGTEKAVIAMCHLRALPGDPSFDAQLGMNWVIDKAWDDLMALQNGGVDAVMFS
Secondary structure 
SS confidence 
Disorder  ???
??
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  NEFSLPYLTKVRPETTAAMARIIGQLMSDIRIPFGVNVLWDPVASFDLAMATGAKFIREI
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  FTGAYASDFGVWDTNVGETIRHQHRIGAGEVKTLFNIVPEAAVYLGNRDICSIAKSTVFN
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  NHPDALCVSGLTAGTRTDSALLKRVKETVPDTVVLANTGVCLENVEEQLSIADGCVTATT
Secondary structure 
SS confidence 
Disorder 
?????
Disorder confidence 
 
   .........250.........260........
Sequence  FKKDGVFANFVDQARVSQFMEKVHHIRR
Secondary structure 
SS confidence 
Disorder 
?
???
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2ekc chain A

3D model

Region: 1 - 265
Aligned: 238
Modelled: 265
Confidence: 100.0%
Identity: 17%
PDB header:lyase
Chain: A: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5

Phyre2

PDB 3nav chain B

3D model

Region: 1 - 268
Aligned: 241
Modelled: 266
Confidence: 100.0%
Identity: 13%
PDB header:lyase
Chain: B: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: crystal structure of an alpha subunit of tryptophan synthase from2 vibrio cholerae o1 biovar el tor str. n16961

Phyre2

PDB 1ujp chain A

3D model

Region: 1 - 268
Aligned: 237
Modelled: 260
Confidence: 100.0%
Identity: 16%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Tryptophan biosynthesis enzymes

Phyre2

PDB 1qop chain A

3D model

Region: 1 - 268
Aligned: 250
Modelled: 268
Confidence: 100.0%
Identity: 15%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Tryptophan biosynthesis enzymes

Phyre2

PDB 3tha chain B

3D model

Region: 6 - 262
Aligned: 235
Modelled: 254
Confidence: 100.0%
Identity: 11%
PDB header:lyase
Chain: B: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: tryptophan synthase subunit alpha from campylobacter jejuni.

Phyre2

PDB 1geq chain A

3D model

Region: 7 - 266
Aligned: 234
Modelled: 252
Confidence: 100.0%
Identity: 16%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Tryptophan biosynthesis enzymes

Phyre2

PDB 1rd5 chain A

3D model

Region: 2 - 265
Aligned: 243
Modelled: 251
Confidence: 100.0%
Identity: 15%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Tryptophan biosynthesis enzymes

Phyre2

PDB 1viz chain A

3D model

Region: 19 - 265
Aligned: 209
Modelled: 235
Confidence: 100.0%
Identity: 15%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 1xcf chain A

3D model

Region: 1 - 268
Aligned: 226
Modelled: 247
Confidence: 100.0%
Identity: 17%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Tryptophan biosynthesis enzymes

Phyre2

PDB 2f6u chain A domain 1

3D model

Region: 19 - 245
Aligned: 192
Modelled: 225
Confidence: 99.9%
Identity: 20%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 1j5t chain A

3D model

Region: 1 - 268
Aligned: 219
Modelled: 242
Confidence: 99.8%
Identity: 16%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Tryptophan biosynthesis enzymes

Phyre2

PDB 3igs chain B

3D model

Region: 18 - 267
Aligned: 199
Modelled: 228
Confidence: 99.7%
Identity: 12%
PDB header:isomerase
Chain: B: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase 2;
PDBTitle: structure of the salmonella enterica n-acetylmannosamine-6-phosphate2 2-epimerase

Phyre2

PDB 2c3z chain A

3D model

Region: 2 - 260
Aligned: 206
Modelled: 242
Confidence: 99.6%
Identity: 12%
PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus

Phyre2

PDB 3q58 chain A

3D model

Region: 18 - 265
Aligned: 196
Modelled: 219
Confidence: 99.6%
Identity: 13%
PDB header:isomerase
Chain: A: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase;
PDBTitle: structure of n-acetylmannosamine-6-phosphate epimerase from salmonella2 enterica

Phyre2

PDB 1rpx chain A

3D model

Region: 2 - 268
Aligned: 220
Modelled: 253
Confidence: 99.5%
Identity: 12%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: D-ribulose-5-phosphate 3-epimerase

Phyre2

PDB 3qc3 chain B

3D model

Region: 43 - 267
Aligned: 195
Modelled: 208
Confidence: 99.5%
Identity: 8%
PDB header:isomerase
Chain: B: PDB Molecule:d-ribulose-5-phosphate-3-epimerase;
PDBTitle: crystal structure of a d-ribulose-5-phosphate-3-epimerase (np_954699)2 from homo sapiens at 2.20 a resolution

Phyre2

PDB 1yxy chain A domain 1

3D model

Region: 17 - 264
Aligned: 209
Modelled: 230
Confidence: 99.5%
Identity: 11%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: NanE-like

Phyre2

PDB 1pii chain A domain 2

3D model

Region: 4 - 260
Aligned: 211
Modelled: 241
Confidence: 99.5%
Identity: 11%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Tryptophan biosynthesis enzymes

Phyre2

PDB 3ct7 chain E

3D model

Region: 43 - 265
Aligned: 195
Modelled: 209
Confidence: 99.5%
Identity: 7%
PDB header:isomerase
Chain: E: PDB Molecule:d-allulose-6-phosphate 3-epimerase;
PDBTitle: crystal structure of d-allulose 6-phosphate 3-epimerase2 from escherichia coli k-12

Phyre2

PDB 1h1y chain A

3D model

Region: 44 - 265
Aligned: 196
Modelled: 213
Confidence: 99.4%
Identity: 12%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: D-ribulose-5-phosphate 3-epimerase

Phyre2
1
c2ekcA_
2
c3navB_
3
d1ujpa_
4
d1qopa_
5
c3thaB_
6
d1geqa_
7
d1rd5a_
8
d1viza_
9
d1xcfa_
10
d2f6ua1
11
d1j5ta_
12
c3igsB_
13
c2c3zA_
14
c3q58A_
15
d1rpxa_
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c3qc3B_
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d1yxya1
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d1piia2
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c3ct7E_
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d1h1ya_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2ekcA_
100.0 17 PDB header:lyase
Chain: A: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5
2c3navB_
100.0 13 PDB header:lyase
Chain: B: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: crystal structure of an alpha subunit of tryptophan synthase from2 vibrio cholerae o1 biovar el tor str. n16961
3d1ujpa_
100.0 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
4d1qopa_
100.0 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
5c3thaB_
100.0 11 PDB header:lyase
Chain: B: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: tryptophan synthase subunit alpha from campylobacter jejuni.
6d1geqa_
100.0 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
7d1rd5a_
100.0 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
8d1viza_
100.0 15 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
9d1xcfa_
100.0 17 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
10d2f6ua1
99.9 20 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
11d1j5ta_
99.8 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
12c3igsB_
99.7 12 PDB header:isomerase
Chain: B: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase 2;
PDBTitle: structure of the salmonella enterica n-acetylmannosamine-6-phosphate2 2-epimerase
13c2c3zA_
99.6 12 PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus
14c3q58A_
99.6 13 PDB header:isomerase
Chain: A: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase;
PDBTitle: structure of n-acetylmannosamine-6-phosphate epimerase from salmonella2 enterica
15d1rpxa_
99.5 12 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
16c3qc3B_
99.5 8 PDB header:isomerase
Chain: B: PDB Molecule:d-ribulose-5-phosphate-3-epimerase;
PDBTitle: crystal structure of a d-ribulose-5-phosphate-3-epimerase (np_954699)2 from homo sapiens at 2.20 a resolution
17d1yxya1
99.5 11 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:NanE-like
18d1piia2
99.5 11 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
19c3ct7E_
99.5 7 PDB header:isomerase
Chain: E: PDB Molecule:d-allulose-6-phosphate 3-epimerase;
PDBTitle: crystal structure of d-allulose 6-phosphate 3-epimerase2 from escherichia coli k-12
20d1h1ya_
99.4 12 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
21d1tqxa_
not modelled 99.4 10 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
22c3f4wA_
not modelled 99.4 11 PDB header:synthase, lyase
Chain: A: PDB Molecule:putative hexulose 6 phosphate synthase;
PDBTitle: the 1.65a crystal structure of 3-hexulose-6-phosphate2 synthase from salmonella typhimurium
23d1tqja_
not modelled 99.4 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
24d1thfd_
not modelled 99.3 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
25d1y0ea_
not modelled 99.3 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:NanE-like
26d1dvja_
not modelled 99.3 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
27c3jr2D_
not modelled 99.3 10 PDB header:biosynthetic protein
Chain: D: PDB Molecule:hexulose-6-phosphate synthase sgbh;
PDBTitle: x-ray crystal structure of the mg-bound 3-keto-l-gulonate-6-phosphate2 decarboxylase from vibrio cholerae o1 biovar el tor str. n16961
28c3qjaA_
not modelled 99.2 13 PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of the mycobacterium tuberculosis indole-3-glycerol2 phosphate synthase (trpc) in apo form
29d1ka9f_
not modelled 99.2 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
30d2czda1
not modelled 99.2 9 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
31d1a53a_
not modelled 99.2 10 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
32d1q6oa_
not modelled 99.2 11 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
33d1vc4a_
not modelled 99.2 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
34d2flia1
not modelled 99.2 9 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
35d2tpsa_
not modelled 99.2 14 Fold:TIM beta/alpha-barrel
Superfamily:Thiamin phosphate synthase
Family:Thiamin phosphate synthase
36d1wa3a1
not modelled 99.2 19 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
37d1h5ya_
not modelled 99.2 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
38c3ajxA_
not modelled 99.1 11 PDB header:lyase
Chain: A: PDB Molecule:3-hexulose-6-phosphate synthase;
PDBTitle: crystal structure of 3-hexulose-6-phosphate synthase
39d1i4na_
not modelled 99.1 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
40d1wbha1
not modelled 99.1 17 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
41d1vzwa1
not modelled 99.1 12 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
42c3inpA_
not modelled 99.1 12 PDB header:isomerase
Chain: A: PDB Molecule:d-ribulose-phosphate 3-epimerase;
PDBTitle: 2.05 angstrom resolution crystal structure of d-ribulose-phosphate 3-2 epimerase from francisella tularensis.
43d1nsja_
not modelled 99.0 18 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
44d1znna1
not modelled 99.0 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:PdxS-like
45d1v5xa_
not modelled 99.0 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
46c1znnF_
not modelled 99.0 15 PDB header:biosynthetic protein
Chain: F: PDB Molecule:plp synthase;
PDBTitle: structure of the synthase subunit of plp synthase
47c3exsB_
not modelled 98.9 10 PDB header:lyase
Chain: B: PDB Molecule:rmpd (hexulose-6-phosphate synthase);
PDBTitle: crystal structure of kgpdc from streptococcus mutans in2 complex with d-r5p
48d1vhca_
not modelled 98.9 14 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
49c2y85D_
not modelled 98.9 14 PDB header:isomerase
Chain: D: PDB Molecule:phosphoribosyl isomerase a;
PDBTitle: crystal structure of mycobacterium tuberculosis phosphoribosyl2 isomerase with bound rcdrp
50c1piiA_
not modelled 98.9 14 PDB header:bifunctional(isomerase and synthase)
Chain: A: PDB Molecule:n-(5'phosphoribosyl)anthranilate isomerase;
PDBTitle: three-dimensional structure of the bifunctional enzyme2 phosphoribosylanthranilate isomerase:3 indoleglycerolphosphate synthase from escherichia coli4 refined at 2.0 angstroms resolution
51d1piia1
not modelled 98.8 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
52d1km4a_
not modelled 98.8 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
53d1xi3a_
not modelled 98.7 18 Fold:TIM beta/alpha-barrel
Superfamily:Thiamin phosphate synthase
Family:Thiamin phosphate synthase
54c3labA_
not modelled 98.7 20 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative kdpg (2-keto-3-deoxy-6-phosphogluconate)
PDBTitle: crystal structure of a putative kdpg (2-keto-3-deoxy-6-2 phosphogluconate) aldolase from oleispira antarctica
55c2v82A_
not modelled 98.7 18 PDB header:lyase
Chain: A: PDB Molecule:2-dehydro-3-deoxy-6-phosphogalactonate aldolase;
PDBTitle: kdpgal complexed to kdpgal
56c2z6jB_
not modelled 98.6 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:trans-2-enoyl-acp reductase ii;
PDBTitle: crystal structure of s. pneumoniae enoyl-acyl carrier2 protein reductase (fabk) in complex with an inhibitor
57d1mxsa_
not modelled 98.6 15 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
58c2w6rA_
not modelled 98.6 14 PDB header:lyase
Chain: A: PDB Molecule:imidazole glycerol phosphate synthase subunit
PDBTitle: crystal structure of an artificial (ba)8-barrel protein2 designed from identical half barrels
59d1twda_
not modelled 98.6 15 Fold:TIM beta/alpha-barrel
Superfamily:CutC-like
Family:CutC-like
60d1xm3a_
not modelled 98.5 12 Fold:TIM beta/alpha-barrel
Superfamily:ThiG-like
Family:ThiG-like
61c3bo9B_
not modelled 98.5 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative nitroalkan dioxygenase;
PDBTitle: crystal structure of putative nitroalkan dioxygenase (tm0800) from2 thermotoga maritima at 2.71 a resolution
62c1yadD_
not modelled 98.4 13 PDB header:transcription
Chain: D: PDB Molecule:regulatory protein teni;
PDBTitle: structure of teni from bacillus subtilis
63d1jvna1
not modelled 98.4 18 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
64d1wv2a_
not modelled 98.4 14 Fold:TIM beta/alpha-barrel
Superfamily:ThiG-like
Family:ThiG-like
65c3o63B_
not modelled 98.3 14 PDB header:transferase
Chain: B: PDB Molecule:probable thiamine-phosphate pyrophosphorylase;
PDBTitle: crystal structure of thiamin phosphate synthase from mycobacterium2 tuberculosis
66c1jvnB_
not modelled 98.3 18 PDB header:transferase
Chain: B: PDB Molecule:bifunctional histidine biosynthesis protein hishf;
PDBTitle: crystal structure of imidazole glycerol phosphate synthase: a tunnel2 through a (beta/alpha)8 barrel joins two active sites
67c3bw2A_
not modelled 98.3 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-nitropropane dioxygenase;
PDBTitle: crystal structures and site-directed mutagenesis study of nitroalkane2 oxidase from streptomyces ansochromogenes
68d1d3ga_
not modelled 98.3 15 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
69c3gr7A_
not modelled 98.2 11 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadph dehydrogenase;
PDBTitle: structure of oye from geobacillus kaustophilus, hexagonal2 crystal form
70d1w0ma_
not modelled 98.2 16 Fold:TIM beta/alpha-barrel
Superfamily:Triosephosphate isomerase (TIM)
Family:Triosephosphate isomerase (TIM)
71c2htmB_
not modelled 98.2 16 PDB header:biosynthetic protein
Chain: B: PDB Molecule:thiazole biosynthesis protein thig;
PDBTitle: crystal structure of ttha0676 from thermus thermophilus hb8
72c2gjlA_
not modelled 98.2 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:hypothetical protein pa1024;
PDBTitle: crystal structure of 2-nitropropane dioxygenase
73c2yw3E_
not modelled 98.2 15 PDB header:lyase
Chain: E: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase/2-deydro-3-
PDBTitle: crystal structure analysis of the 4-hydroxy-2-oxoglutarate aldolase/2-2 deydro-3-deoxyphosphogluconate aldolase from tthb1
74d1gtea2
not modelled 98.2 13 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
75c3iwpK_
not modelled 98.1 18 PDB header:metal binding protein
Chain: K: PDB Molecule:copper homeostasis protein cutc homolog;
PDBTitle: crystal structure of human copper homeostasis protein cutc
76d1uuma_
not modelled 98.1 17 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
77d1z41a1
not modelled 98.1 15 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
78c3hf3A_
not modelled 98.0 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:chromate reductase;
PDBTitle: old yellow enzyme from thermus scotoductus sa-01
79d2b4ga1
not modelled 98.0 11 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
80c3nm3D_
not modelled 98.0 14 PDB header:transferase
Chain: D: PDB Molecule:thiamine biosynthetic bifunctional enzyme;
PDBTitle: the crystal structure of candida glabrata thi6, a bifunctional enzyme2 involved in thiamin biosyhthesis of eukaryotes
81c1tv5A_
not modelled 98.0 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydroorotate dehydrogenase homolog, mitochondrial;
PDBTitle: plasmodium falciparum dihydroorotate dehydrogenase with a bound2 inhibitor
82d1tv5a1
not modelled 98.0 17 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
83c2fptA_
not modelled 98.0 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydroorotate dehydrogenase, mitochondrial;
PDBTitle: dual binding mode of a novel series of dhodh inhibitors
84c2bdqA_
not modelled 98.0 14 PDB header:metal transport
Chain: A: PDB Molecule:copper homeostasis protein cutc;
PDBTitle: crystal structure of the putative copper homeostasis2 protein cutc from streptococcus agalactiae, northeast3 strucural genomics target sar15.
85d1juba_
not modelled 97.9 11 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
86d1ps9a1
not modelled 97.9 15 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
87c2h90A_
not modelled 97.9 11 PDB header:oxidoreductase
Chain: A: PDB Molecule:xenobiotic reductase a;
PDBTitle: xenobiotic reductase a in complex with coumarin
88c3ru6C_
not modelled 97.8 12 PDB header:lyase
Chain: C: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: 1.8 angstrom resolution crystal structure of orotidine 5'-phosphate2 decarboxylase (pyrf) from campylobacter jejuni subsp. jejuni nctc3 11168
89c3tdmD_
not modelled 97.8 11 PDB header:de novo protein
Chain: D: PDB Molecule:computationally designed two-fold symmetric tim-barrel
PDBTitle: computationally designed tim-barrel protein, halfflr
90d1hg3a_
not modelled 97.8 14 Fold:TIM beta/alpha-barrel
Superfamily:Triosephosphate isomerase (TIM)
Family:Triosephosphate isomerase (TIM)
91c1ps9A_
not modelled 97.6 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:2,4-dienoyl-coa reductase;
PDBTitle: the crystal structure and reaction mechanism of e. coli 2,4-2 dienoyl coa reductase
92c1zfjA_
not modelled 97.6 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine monophosphate dehydrogenase;
PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes
93d1f76a_
not modelled 97.6 17 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
94c3gyeA_
not modelled 97.6 9 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydroorotate dehydrogenase, putative;
PDBTitle: didydroorotate dehydrogenase from leishmania major
95d1djqa1
not modelled 97.6 14 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
96c3kruC_
not modelled 97.5 15 PDB header:oxidoreductase
Chain: C: PDB Molecule:nadh:flavin oxidoreductase/nadh oxidase;
PDBTitle: crystal structure of the thermostable old yellow enzyme from2 thermoanaerobacter pseudethanolicus e39
97c2agkA_
not modelled 97.5 10 PDB header:isomerase
Chain: A: PDB Molecule:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)
PDBTitle: structure of s. cerevisiae his6 protein
98c3khjE_
not modelled 97.5 12 PDB header:oxidoreductase
Chain: E: PDB Molecule:inosine-5-monophosphate dehydrogenase;
PDBTitle: c. parvum inosine monophosphate dehydrogenase bound by inhibitor c64
99c3gkaB_
not modelled 97.5 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:n-ethylmaleimide reductase;
PDBTitle: crystal structure of n-ethylmaleimidine reductase from2 burkholderia pseudomallei
100c3ceuA_
not modelled 97.5 14 PDB header:transferase
Chain: A: PDB Molecule:thiamine phosphate pyrophosphorylase;
PDBTitle: crystal structure of thiamine phosphate pyrophosphorylase2 (bt_0647) from bacteroides thetaiotaomicron. northeast3 structural genomics consortium target btr268
101c3b0vD_
not modelled 97.5 15 PDB header:oxidoreductase/rna
Chain: D: PDB Molecule:trna-dihydrouridine synthase;
PDBTitle: trna-dihydrouridine synthase from thermus thermophilus in complex with2 trna
102c3femB_
not modelled 97.4 21 PDB header:biosynthetic protein, transferase
Chain: B: PDB Molecule:pyridoxine biosynthesis protein snz1;
PDBTitle: structure of the synthase subunit pdx1.1 (snz1) of plp synthase from2 saccharomyces cerevisiae
103c2zbtB_
not modelled 97.4 22 PDB header:lyase
Chain: B: PDB Molecule:pyridoxal biosynthesis lyase pdxs;
PDBTitle: crystal structure of pyridoxine biosynthesis protein from thermus2 thermophilus hb8
104d1qo2a_
not modelled 97.4 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
105c3tfxB_
not modelled 97.4 8 PDB header:lyase
Chain: B: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: crystal structure of orotidine 5'-phosphate decarboxylase from2 lactobacillus acidophilus
106c2p10D_
not modelled 97.4 14 PDB header:hydrolase
Chain: D: PDB Molecule:mll9387 protein;
PDBTitle: crystal structure of a putative phosphonopyruvate hydrolase (mll9387)2 from mesorhizobium loti maff303099 at 2.15 a resolution
107c2cdh1_
not modelled 97.3 17 PDB header:transferase
Chain: 1: PDB Molecule:enoyl reductase;
PDBTitle: architecture of the thermomyces lanuginosus fungal fatty2 acid synthase at 5 angstrom resolution.
108c2gq8A_
not modelled 97.3 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase, fmn-binding;
PDBTitle: structure of sye1, an oye homologue from s. ondeidensis, in complex2 with p-hydroxyacetophenone
109c3oixA_
not modelled 97.2 9 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative dihydroorotate dehydrogenase; dihydroorotate
PDBTitle: crystal structure of the putative dihydroorotate dehydrogenase from2 streptococcus mutans
110c1jcnA_
not modelled 97.2 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine monophosphate dehydrogenase i;
PDBTitle: binary complex of human type-i inosine monophosphate dehydrogenase2 with 6-cl-imp
111d1ajza_
not modelled 97.2 16 Fold:TIM beta/alpha-barrel
Superfamily:Dihydropteroate synthetase-like
Family:Dihydropteroate synthetase
112d1vhna_
not modelled 97.1 10 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
113c1djnB_
not modelled 97.1 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:trimethylamine dehydrogenase;
PDBTitle: structural and biochemical characterization of recombinant wild type2 trimethylamine dehydrogenase from methylophilus methylotrophus (sp.3 w3a1)
114c2h6rG_
not modelled 97.1 25 PDB header:isomerase
Chain: G: PDB Molecule:triosephosphate isomerase;
PDBTitle: crystal structure of triosephosphate isomerase (tim) from2 methanocaldococcus jannaschii
115c3tr9A_
not modelled 97.1 17 PDB header:transferase
Chain: A: PDB Molecule:dihydropteroate synthase;
PDBTitle: structure of a dihydropteroate synthase (folp) in complex with pteroic2 acid from coxiella burnetii
116d1vcfa1
not modelled 97.1 16 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
117d1ep3a_
not modelled 97.0 19 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
118d1vyra_
not modelled 97.0 10 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
119c2yzrB_
not modelled 97.0 14 PDB header:lyase
Chain: B: PDB Molecule:pyridoxal biosynthesis lyase pdxs;
PDBTitle: crystal structure of pyridoxine biosynthesis protein from2 methanocaldococcus jannaschii
120c3k30B_
not modelled 97.0 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:histamine dehydrogenase;
PDBTitle: histamine dehydrogenase from nocardiodes simplex

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0