Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP76585
DateThu Jan 5 12:24:52 GMT 2012
Unique Job ID3e24117744b4e7d2

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2xpiA_
Top template information
PDB header:cell cycle
Chain: A: PDB Molecule:anaphase-promoting complex subunit cut9;
PDBTitle: crystal structure of apc/c hetero-tetramer cut9-hcn1
Confidence and coverage
Confidence:100.0% Coverage: 46%
507 residues ( 46% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
882 residues ( 81%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MTPVKVWQERVEIPTYETGPQDIHPMFLENRVYQGSSGAVYPYGVTDTLSEQKTLKSWQA
Secondary structure 
SS confidence 
Disorder  ?????????
?????????
?
???
??
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  VWLENDYIKVMILPELGGRVHRAWDKVKQRDFVYHNEVIKPALVGLLGPWISGGIEFNWP
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  QHHRPTTFMPVDFTLEAHEDGAQTVWVGETEPMHGLQVMTGFTLRPDRAALEIASRVYNG
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  NATPRHFLWWANPAVKGGEGHQSVFPPDVTAVFDHGKRAVSAFPIATGTYYKVDYSAGVD
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  ISRYKNVPVPTSYMAEKSQYDFVGAWCHDEDGGLLHVANHHIAPGKKQWSWGHSEFGQAW
Secondary structure 
SS confidence 
Disorder 
??
???
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  DKSLTDNNGPYIELMTGIFADNQPDFTWLDAYEEKRFEQYFLPYHSLGMVQNASRDAVIK
Secondary structure 
SS confidence 
Disorder 
?????
?
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  LQRSKRGIEWGLYAISPLNGYRLAIREIGKCNALLDDAVALMPATAIQGVLHGINPERLT
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........430.........440.........450.........460.........470.........480
Sequence  IELSDADGNIVLSYQEHQPQALPLPDVAKAPLAAQDITSTDEAWFIGQHLEQYHHASRSP
Secondary structure 
SS confidence 
Disorder 
?
???????
?
??
????
?
Disorder confidence 
 
   .........490.........500.........510.........520.........530.........540
Sequence  FDYYLRGVALDPLDYRCNLALAMLEYNRADFPQAVAYATQALKRAHALNKNPQCGQASLI
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........550.........560.........570.........580.........590.........600
Sequence  RASAYERQGQYQQAEEDFWRAVWSGNSKAGGYYGLARLAARNGNFDAGLDFCQQSLRACP
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........610.........620.........630.........640.........650.........660
Sequence  TNQEVLCLHNLLLVLSGRQDNARVQREKLLRDYPLNATLWWLNWFDGRSESALAQWRGLC
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........670.........680.........690.........700.........710.........720
Sequence  QGRDVNALMTAGQLINWGMPTLAAEMLNALDCQRTLPLYLQASLLPKAERGELVAKAIDV
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........730.........740.........750.........760.........770.........780
Sequence  FPQFVRFPNTLEEVAALESIEECWFARHLLACFYYNKRSYNKAIAFWQRCVEMSPEFADG
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........790.........800.........810.........820.........830.........840
Sequence  WRGLAIHAWNKQHDYELAARYLDNAYQLAPQDARLLFERDLLDKLSGATPEKRLARLENN
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........850.........860.........870.........880.........890.........900
Sequence  LEIALKRDDMTAELLNLWHLTGQADKAADILATRKFHPWEGGEGKVTSQFILNQLLRAWQ
Secondary structure 
SS confidence 
Disorder 
?
????
Disorder confidence 
 
   .........910.........920.........930.........940.........950.........960
Sequence  HLDARQPQQACELLHAALHYPENLSEGRLPGQTDNDIWFWQAICANAQGDETEATRCLRL
Secondary structure 
SS confidence 
Disorder 
?
???
Disorder confidence 
 
   .........970.........980.........990.........1000.........1010.........1020
Sequence  AATGDRTINIHSYYNDQPVDYLFWQGMALRLLGEQQTAQQLFSEMKQWAQEMAKTSIEAD
Secondary structure 
SS confidence 
Disorder 
?
?
?
?
?
Disorder confidence 
 
   .........1030.........1040.........1050.........1060.........1070.........1080
Sequence  FFAVSQPDLLSLYGDLQQQHKEKCLMVAMLASAGLGEVAQYESARAELTAINPAWPKAAL
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........1090...
Sequence  FTTVMPFIFNRVH
Secondary structure 
SS confidence 
Disorder 
??????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2xpi chain A

3D model

Region: 448 - 1085
Aligned: 507
Modelled: 529
Confidence: 100.0%
Identity: 12%
PDB header:cell cycle
Chain: A: PDB Molecule:anaphase-promoting complex subunit cut9;
PDBTitle: crystal structure of apc/c hetero-tetramer cut9-hcn1

Phyre2

PDB 1w3b chain A

3D model

Region: 498 - 950
Aligned: 387
Modelled: 414
Confidence: 100.0%
Identity: 18%
Fold: alpha-alpha superhelix
Superfamily: TPR-like
Family: Tetratricopeptide repeat (TPR)

Phyre2

PDB 3fp4 chain A

3D model

Region: 535 - 1025
Aligned: 456
Modelled: 489
Confidence: 100.0%
Identity: 11%
PDB header:transport protein
Chain: A: PDB Molecule:tpr repeat-containing protein yhr117w;
PDBTitle: crystal structure of tom71 complexed with ssa1 c-terminal2 fragment

Phyre2

PDB 2gw1 chain A

3D model

Region: 495 - 1004
Aligned: 477
Modelled: 505
Confidence: 100.0%
Identity: 10%
PDB header:protein transport
Chain: A: PDB Molecule:mitochondrial precursor proteins import receptor;
PDBTitle: crystal structure of the yeast tom70

Phyre2

PDB 2ooe chain A domain 1

3D model

Region: 485 - 1022
Aligned: 500
Modelled: 538
Confidence: 100.0%
Identity: 8%
Fold: alpha-alpha superhelix
Superfamily: TPR-like
Family: HAT/Suf repeat

Phyre2

PDB 2y4t chain A

3D model

Region: 534 - 1039
Aligned: 399
Modelled: 425
Confidence: 99.9%
Identity: 18%
PDB header:chaperone
Chain: A: PDB Molecule:dnaj homolog subfamily c member 3;
PDBTitle: crystal structure of the human co-chaperone p58(ipk)

Phyre2

PDB 3ieg chain B

3D model

Region: 534 - 996
Aligned: 356
Modelled: 382
Confidence: 99.9%
Identity: 17%
PDB header:chaperone
Chain: B: PDB Molecule:dnaj homolog subfamily c member 3;
PDBTitle: crystal structure of p58(ipk) tpr domain at 2.5 a

Phyre2

PDB 3hym chain B

3D model

Region: 493 - 829
Aligned: 296
Modelled: 303
Confidence: 99.9%
Identity: 9%
PDB header:cell cycle, ligase
Chain: B: PDB Molecule:cell division cycle protein 16 homolog;
PDBTitle: insights into anaphase promoting complex tpr subdomain2 assembly from a cdc26-apc6 structure

Phyre2

PDB 1qsa chain A domain 1

3D model

Region: 496 - 966
Aligned: 415
Modelled: 443
Confidence: 99.9%
Identity: 9%
Fold: alpha-alpha superhelix
Superfamily: Bacterial muramidases
Family: Bacterial muramidases

Phyre2

PDB 1fch chain B

3D model

Region: 529 - 965
Aligned: 280
Modelled: 296
Confidence: 99.9%
Identity: 16%
PDB header:signaling protein
Chain: B: PDB Molecule:peroxisomal targeting signal 1 receptor;
PDBTitle: crystal structure of the pts1 complexed to the tpr region2 of human pex5

Phyre2

PDB 1fch chain A

3D model

Region: 482 - 807
Aligned: 282
Modelled: 289
Confidence: 99.8%
Identity: 14%
Fold: alpha-alpha superhelix
Superfamily: TPR-like
Family: Tetratricopeptide repeat (TPR)

Phyre2

PDB 2uy1 chain A

3D model

Region: 493 - 996
Aligned: 416
Modelled: 431
Confidence: 99.8%
Identity: 11%
PDB header:rna-binding protein
Chain: A: PDB Molecule:cleavage stimulation factor 77;
PDBTitle: crystal structure of cstf-77

Phyre2

PDB 3pe3 chain D

3D model

Region: 456 - 634
Aligned: 173
Modelled: 179
Confidence: 99.8%
Identity: 13%
PDB header:transferase
Chain: D: PDB Molecule:udp-n-acetylglucosamine--peptide n-
PDBTitle: structure of human o-glcnac transferase and its complex with a peptide2 substrate

Phyre2

PDB 1dce chain A domain 1

3D model

Region: 461 - 785
Aligned: 276
Modelled: 282
Confidence: 99.8%
Identity: 13%
Fold: alpha-alpha superhelix
Superfamily: Protein prenylyltransferase
Family: Protein prenylyltransferase

Phyre2

PDB 1xi4 chain D

3D model

Region: 452 - 1088
Aligned: 523
Modelled: 560
Confidence: 99.8%
Identity: 13%
PDB header:endocytosis/exocytosis
Chain: D: PDB Molecule:clathrin heavy chain;
PDBTitle: clathrin d6 coat

Phyre2

PDB 1tno chain I

3D model

Region: 491 - 861
Aligned: 258
Modelled: 264
Confidence: 99.8%
Identity: 13%
PDB header:transferase
Chain: I: PDB Molecule:geranylgeranyltransferase type i alpha subunit;
PDBTitle: rat protein geranylgeranyltransferase type-i complexed with2 a ggpp analog and a kkksktkcvim peptide derived from k-3 ras4b

Phyre2

PDB 2h6f chain A domain 1

3D model

Region: 488 - 860
Aligned: 260
Modelled: 266
Confidence: 99.8%
Identity: 11%
Fold: alpha-alpha superhelix
Superfamily: Protein prenylyltransferase
Family: Protein prenylyltransferase

Phyre2

PDB 1d8d chain A

3D model

Region: 487 - 868
Aligned: 269
Modelled: 275
Confidence: 99.8%
Identity: 13%
Fold: alpha-alpha superhelix
Superfamily: Protein prenylyltransferase
Family: Protein prenylyltransferase

Phyre2

PDB 1hz4 chain A

3D model

Region: 486 - 1007
Aligned: 347
Modelled: 356
Confidence: 99.8%
Identity: 13%
Fold: alpha-alpha superhelix
Superfamily: TPR-like
Family: Transcription factor MalT domain III

Phyre2

PDB 3cvp chain A

3D model

Region: 529 - 812
Aligned: 271
Modelled: 284
Confidence: 99.8%
Identity: 11%
PDB header:transport protein
Chain: A: PDB Molecule:peroxisome targeting signal 1 receptor pex5;
PDBTitle: structure of peroxisomal targeting signal 1 (pts1) binding2 domain of trypanosoma brucei peroxin 5 (tbpex5)complexed3 to pts1 peptide (10-skl)

Phyre2

PDB 3nre chain B

3D model

Region: 58 - 338
Aligned: 255
Modelled: 252
Confidence: 99.4%
Identity: 14%
PDB header:isomerase
Chain: B: PDB Molecule:aldose 1-epimerase;
PDBTitle: crystal structure of a putative aldose 1-epimerase (b2544) from2 escherichia coli k12 at 1.59 a resolution

Phyre2

PDB 3mwx chain A

3D model

Region: 51 - 338
Aligned: 267
Modelled: 262
Confidence: 99.3%
Identity: 18%
PDB header:isomerase
Chain: A: PDB Molecule:aldose 1-epimerase;
PDBTitle: crystal structure of a putative galactose mutarotase (bsu18360) from2 bacillus subtilis at 1.45 a resolution

Phyre2

PDB 3os7 chain B

3D model

Region: 49 - 338
Aligned: 267
Modelled: 264
Confidence: 99.2%
Identity: 13%
PDB header:isomerase
Chain: B: PDB Molecule:galactose mutarotase-like protein;
PDBTitle: crystal structure of a galactose mutarotase-like protein (ca_c0697)2 from clostridium acetobutylicum at 1.80 a resolution

Phyre2

PDB 3os7 chain D

3D model

Region: 49 - 338
Aligned: 273
Modelled: 270
Confidence: 99.2%
Identity: 15%
PDB header:isomerase
Chain: D: PDB Molecule:galactose mutarotase-like protein;
PDBTitle: crystal structure of a galactose mutarotase-like protein (ca_c0697)2 from clostridium acetobutylicum at 1.80 a resolution

Phyre2

PDB 3q1n chain A

3D model

Region: 60 - 338
Aligned: 254
Modelled: 250
Confidence: 99.1%
Identity: 17%
PDB header:isomerase
Chain: A: PDB Molecule:galactose mutarotase related enzyme;
PDBTitle: crystal structure of a galactose mutarotase-like protein (lsei_2598)2 from lactobacillus casei atcc 334 at 1.61 a resolution

Phyre2
1
c2xpiA_
2
d1w3ba_
3
c3fp4A_
4
c2gw1A_
5
d2ooea1
6
c2y4tA_
7
c3iegB_
8
c3hymB_
9
d1qsaa1
10
c1fchB_
11
d1fcha_
12
c2uy1A_
13
c3pe3D_
14
d1dcea1
15
c1xi4D_
16
c1tnoI_
17
d2h6fa1
18
d1d8da_
19
d1hz4a_
20
c3cvpA_
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
c3nreB_
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
c3mwxA_
71
72
73
c3os7B_
74
75
76
77
c3os7D_
78
79
80
81
c3q1nA_
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2xpiA_
100.0 12 PDB header:cell cycle
Chain: A: PDB Molecule:anaphase-promoting complex subunit cut9;
PDBTitle: crystal structure of apc/c hetero-tetramer cut9-hcn1
2d1w3ba_
100.0 18 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
3c3fp4A_
100.0 11 PDB header:transport protein
Chain: A: PDB Molecule:tpr repeat-containing protein yhr117w;
PDBTitle: crystal structure of tom71 complexed with ssa1 c-terminal2 fragment
4c2gw1A_
100.0 10 PDB header:protein transport
Chain: A: PDB Molecule:mitochondrial precursor proteins import receptor;
PDBTitle: crystal structure of the yeast tom70
5d2ooea1
100.0 8 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:HAT/Suf repeat
6c2y4tA_
99.9 18 PDB header:chaperone
Chain: A: PDB Molecule:dnaj homolog subfamily c member 3;
PDBTitle: crystal structure of the human co-chaperone p58(ipk)
7c3iegB_
99.9 17 PDB header:chaperone
Chain: B: PDB Molecule:dnaj homolog subfamily c member 3;
PDBTitle: crystal structure of p58(ipk) tpr domain at 2.5 a
8c3hymB_
99.9 9 PDB header:cell cycle, ligase
Chain: B: PDB Molecule:cell division cycle protein 16 homolog;
PDBTitle: insights into anaphase promoting complex tpr subdomain2 assembly from a cdc26-apc6 structure
9d1qsaa1
99.9 9 Fold:alpha-alpha superhelix
Superfamily:Bacterial muramidases
Family:Bacterial muramidases
10c1fchB_
99.9 16 PDB header:signaling protein
Chain: B: PDB Molecule:peroxisomal targeting signal 1 receptor;
PDBTitle: crystal structure of the pts1 complexed to the tpr region2 of human pex5
11d1fcha_
99.8 14 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
12c2uy1A_
99.8 11 PDB header:rna-binding protein
Chain: A: PDB Molecule:cleavage stimulation factor 77;
PDBTitle: crystal structure of cstf-77
13c3pe3D_
99.8 13 PDB header:transferase
Chain: D: PDB Molecule:udp-n-acetylglucosamine--peptide n-
PDBTitle: structure of human o-glcnac transferase and its complex with a peptide2 substrate
14d1dcea1
99.8 13 Fold:alpha-alpha superhelix
Superfamily:Protein prenylyltransferase
Family:Protein prenylyltransferase
15c1xi4D_
99.8 13 PDB header:endocytosis/exocytosis
Chain: D: PDB Molecule:clathrin heavy chain;
PDBTitle: clathrin d6 coat
16c1tnoI_
99.8 13 PDB header:transferase
Chain: I: PDB Molecule:geranylgeranyltransferase type i alpha subunit;
PDBTitle: rat protein geranylgeranyltransferase type-i complexed with2 a ggpp analog and a kkksktkcvim peptide derived from k-3 ras4b
17d2h6fa1
99.8 11 Fold:alpha-alpha superhelix
Superfamily:Protein prenylyltransferase
Family:Protein prenylyltransferase
18d1d8da_
99.8 13 Fold:alpha-alpha superhelix
Superfamily:Protein prenylyltransferase
Family:Protein prenylyltransferase
19d1hz4a_
99.8 13 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Transcription factor MalT domain III
20c3cvpA_
99.8 11 PDB header:transport protein
Chain: A: PDB Molecule:peroxisome targeting signal 1 receptor pex5;
PDBTitle: structure of peroxisomal targeting signal 1 (pts1) binding2 domain of trypanosoma brucei peroxin 5 (tbpex5)complexed3 to pts1 peptide (10-skl)
21c3q75A_
not modelled 99.8 15 PDB header:transferase
Chain: A: PDB Molecule:farnesyltransferase alpha subunit;
PDBTitle: cryptococcus neoformans protein farnesyltransferase in complex with2 fpt-ii and tkcvvm peptide
22c2q7fA_
not modelled 99.8 23 PDB header:protein binding
Chain: A: PDB Molecule:yrrb protein;
PDBTitle: crystal structure of yrrb: a tpr protein with an unusual peptide-2 binding site
23c3draA_
not modelled 99.8 10 PDB header:transferase
Chain: A: PDB Molecule:protein
PDBTitle: candida albicans protein geranylgeranyltransferase-i2 complexed with ggpp
24d1xnfa_
not modelled 99.7 15 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
25c3mkrA_
not modelled 99.7 15 PDB header:transport protein
Chain: A: PDB Molecule:coatomer subunit epsilon;
PDBTitle: crystal structure of yeast alpha/epsilon-cop subcomplex of the copi2 vesicular coat
26c2ho1B_
not modelled 99.7 16 PDB header:protein binding
Chain: B: PDB Molecule:type 4 fimbrial biogenesis protein pilf;
PDBTitle: functional characterization of pseudomonas aeruginosa pilf
27c3q15A_
not modelled 99.7 10 PDB header:hydrolase/kinase
Chain: A: PDB Molecule:response regulator aspartate phosphatase h;
PDBTitle: crystal structure of raph complexed with spo0f
28c3mv3B_
not modelled 99.7 11 PDB header:protein transport
Chain: B: PDB Molecule:coatomer subunit epsilon;
PDBTitle: crystal structure of a-cop in complex with e-cop
29c2vq2A_
not modelled 99.6 19 PDB header:structural protein
Chain: A: PDB Molecule:putative fimbrial biogenesis and twitching
PDBTitle: crystal structure of pilw, widely conserved type iv pilus2 biogenesis factor
30c3sf4B_
not modelled 99.6 13 PDB header:signaling protein/protein binding
Chain: B: PDB Molecule:g-protein-signaling modulator 2;
PDBTitle: crystal structure of the complex between the conserved cell polarity2 proteins inscuteable and lgn
31c2r5sB_
not modelled 99.6 13 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein vp0806;
PDBTitle: the crystal structure of a domain of protein vp0806 (unknown function)2 from vibrio parahaemolyticus rimd 2210633
32c3as5A_
not modelled 99.6 13 PDB header:protein binding
Chain: A: PDB Molecule:mama;
PDBTitle: mama amb-1 p212121
33c3ly8A_
not modelled 99.6 10 PDB header:signaling protein
Chain: A: PDB Molecule:transcriptional activator cadc;
PDBTitle: crystal structure of mutant d471e of the periplasmic domain of cadc
34c2hyzA_
not modelled 99.6 24 PDB header:de novo protein
Chain: A: PDB Molecule:synthetic consensus tpr protein;
PDBTitle: crystal structure of an 8 repeat consensus tpr superhelix2 (orthorombic crystal form)
35c2e2eA_
not modelled 99.6 13 PDB header:lyase
Chain: A: PDB Molecule:formate-dependent nitrite reductase complex nrfg subunit;
PDBTitle: tpr domain of nrfg mediates the complex formation between heme lyase2 and formate-dependent nitrite reductase in escherichia coli o157:h7
36c1wao4_
not modelled 99.5 21 PDB header:hydrolase
Chain: 4: PDB Molecule:serine/threonine protein phosphatase 5;
PDBTitle: pp5 structure
37d2c2la1
not modelled 99.5 14 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
38d1hh8a_
not modelled 99.5 13 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
39c3urzB_
not modelled 99.5 15 PDB header:protein binding
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a hypothetical protein (bacova_03105) from2 bacteroides ovatus atcc 8483 at 2.19 a resolution
40c2vyiA_
not modelled 99.5 18 PDB header:chaperone
Chain: A: PDB Molecule:sgta protein;
PDBTitle: crystal structure of the tpr domain of human sgt
41c1slyA_
not modelled 99.5 10 PDB header:glycosyltransferase
Chain: A: PDB Molecule:70-kda soluble lytic transglycosylase;
PDBTitle: complex of the 70-kda soluble lytic transglycosylase with2 bulgecin a
42c2pl2A_
not modelled 99.5 19 PDB header:protein binding
Chain: A: PDB Molecule:hypothetical conserved protein ttc0263;
PDBTitle: crystal structure of ttc0263: a thermophilic tpr protein in thermus2 thermophilus hb27
43c3ulqA_
not modelled 99.5 10 PDB header:gene regulation/transcription activator
Chain: A: PDB Molecule:response regulator aspartate phosphatase f;
PDBTitle: crystal structure of the anti-activator rapf complexed with the2 response regulator coma dna binding domain
44c3gyzB_
not modelled 99.5 12 PDB header:chaperone
Chain: B: PDB Molecule:chaperone protein ipgc;
PDBTitle: crystal structure of ipgc from shigella flexneri
45c3gw4B_
not modelled 99.5 14 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of uncharacterized protein from deinococcus2 radiodurans. northeast structural genomics consortium target drr162b.
46c3qdnA_
not modelled 99.5 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative thioredoxin protein;
PDBTitle: putative thioredoxin protein from salmonella typhimurium
47c2xcbA_
not modelled 99.5 11 PDB header:protein binding
Chain: A: PDB Molecule:regulatory protein pcrh;
PDBTitle: crystal structure of pcrh in complex with the chaperone2 binding region of popd
48d1a17a_
not modelled 99.4 21 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
49c3sz7A_
not modelled 99.4 16 PDB header:chaperone regulator
Chain: A: PDB Molecule:hsc70 cochaperone (sgt);
PDBTitle: crystal structure of the sgt2 tpr domain from aspergillus fumigatus
50c2c2lD_
not modelled 99.4 14 PDB header:chaperone
Chain: D: PDB Molecule:carboxy terminus of hsp70-interacting protein;
PDBTitle: crystal structure of the chip u-box e3 ubiquitin ligase
51d1elwa_
not modelled 99.4 17 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
52c1ihgA_
not modelled 99.4 13 PDB header:isomerase
Chain: A: PDB Molecule:cyclophilin 40;
PDBTitle: bovine cyclophilin 40, monoclinic form
53d1kt1a1
not modelled 99.4 12 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
54c3nreB_
99.4 14 PDB header:isomerase
Chain: B: PDB Molecule:aldose 1-epimerase;
PDBTitle: crystal structure of a putative aldose 1-epimerase (b2544) from2 escherichia coli k12 at 1.59 a resolution
55c2vsnB_
not modelled 99.4 16 PDB header:transferase
Chain: B: PDB Molecule:xcogt;
PDBTitle: structure and topological arrangement of an o-glcnac2 transferase homolog: insight into molecular control of3 intracellular glycosylation
56d1ihga1
not modelled 99.4 13 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
57c2ifuA_
not modelled 99.3 13 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:gamma-snap;
PDBTitle: crystal structure of a gamma-snap from danio rerio
58d1p5qa1
not modelled 99.3 12 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
59c2dbaA_
not modelled 99.3 16 PDB header:structural protein
Chain: A: PDB Molecule:smooth muscle cell associated protein-1, isoform
PDBTitle: the solution structure of the tetratrico peptide repeat of2 human smooth muscle cell associated protein-1, isoform 2
60c3rkvA_
not modelled 99.3 13 PDB header:isomerase
Chain: A: PDB Molecule:putative peptidylprolyl isomerase;
PDBTitle: c-terminal domain of protein c56c10.10, a putative peptidylprolyl2 isomerase, from caenorhabditis elegans
61d2buga1
not modelled 99.3 22 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
62d2onda1
not modelled 99.3 13 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:HAT/Suf repeat
63c1kt0A_
not modelled 99.3 12 PDB header:isomerase
Chain: A: PDB Molecule:51 kda fk506-binding protein;
PDBTitle: structure of the large fkbp-like protein, fkbp51, involved in steroid2 receptor complexes
64c1qz2B_
not modelled 99.3 11 PDB header:isomerase/chaperone
Chain: B: PDB Molecule:fk506-binding protein 4;
PDBTitle: crystal structure of fkbp52 c-terminal domain complex with2 the c-terminal peptide meevd of hsp90
65d1zu2a1
not modelled 99.3 20 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
66d2fbna1
not modelled 99.3 11 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
67c2fbnA_
not modelled 99.3 11 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:70 kda peptidylprolyl isomerase, putative;
PDBTitle: plasmodium falciparum putative fk506-binding protein2 pfl2275c, c-terminal tpr-containing domain
68c3q49B_
not modelled 99.3 16 PDB header:ligase/chaperone
Chain: B: PDB Molecule:stip1 homology and u box-containing protein 1;
PDBTitle: crystal structure of the tpr domain of chip complexed with hsp70-c2 peptide
69c2kckA_
not modelled 99.3 10 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:tpr repeat;
PDBTitle: nmr solution structure of the northeast structural genomics2 consortium (nesg) target mrr121a
70c3mwxA_
99.3 18 PDB header:isomerase
Chain: A: PDB Molecule:aldose 1-epimerase;
PDBTitle: crystal structure of a putative galactose mutarotase (bsu18360) from2 bacillus subtilis at 1.45 a resolution
71d1hxia_
not modelled 99.3 13 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
72c1ltxA_
not modelled 99.2 11 PDB header:transferase/protein binding
Chain: A: PDB Molecule:rab geranylgeranyltransferase alpha subunit;
PDBTitle: structure of rab escort protein-1 in complex with rab2 geranylgeranyl transferase and isoprenoid
73c3os7B_
99.2 13 PDB header:isomerase
Chain: B: PDB Molecule:galactose mutarotase-like protein;
PDBTitle: crystal structure of a galactose mutarotase-like protein (ca_c0697)2 from clostridium acetobutylicum at 1.80 a resolution
74c2yhcA_
not modelled 99.2 19 PDB header:membrane protein
Chain: A: PDB Molecule:upf0169 lipoprotein yfio;
PDBTitle: structure of bamd from e. coli
75c3nf1A_
not modelled 99.2 14 PDB header:motor protein, transport protein
Chain: A: PDB Molecule:kinesin light chain 1;
PDBTitle: crystal structure of the tpr domain of kinesin light chain 1
76c2vgxA_
not modelled 99.2 9 PDB header:chaperone
Chain: A: PDB Molecule:chaperone sycd;
PDBTitle: structure of the yersinia enterocolitica type iii secretion2 translocator chaperone sycd
77c3os7D_
99.2 15 PDB header:isomerase
Chain: D: PDB Molecule:galactose mutarotase-like protein;
PDBTitle: crystal structure of a galactose mutarotase-like protein (ca_c0697)2 from clostridium acetobutylicum at 1.80 a resolution
78d1iyga_
not modelled 99.2 12 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
79c3k9iA_
not modelled 99.2 17 PDB header:protein binding
Chain: A: PDB Molecule:bh0479 protein;
PDBTitle: crystal structure of putative protein binding protein (np_241345.1)2 from bacillus halodurans at 2.71 a resolution
80c2katA_
not modelled 99.2 13 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: solution structure of protein bpp2914 from bordetella2 parapertussis. northeast structural genomics consortium3 target bpr206
81c3q1nA_
99.1 17 PDB header:isomerase
Chain: A: PDB Molecule:galactose mutarotase related enzyme;
PDBTitle: crystal structure of a galactose mutarotase-like protein (lsei_2598)2 from lactobacillus casei atcc 334 at 1.61 a resolution
82d1elra_
not modelled 99.1 18 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
83c2xevB_
not modelled 99.1 17 PDB header:metal binding
Chain: B: PDB Molecule:ybgf;
PDBTitle: crystal structure of the tpr domain of xanthomonas2 campestris ybgf
84c3ceqB_
not modelled 99.1 17 PDB header:motor protein, transport protein
Chain: B: PDB Molecule:kinesin light chain 2;
PDBTitle: the tpr domain of human kinesin light chain 2 (hklc2)
85d1nzna_
not modelled 99.1 12 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
86d1qqea_
not modelled 99.1 9 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
87c3qkyA_
not modelled 99.1 17 PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane assembly lipoprotein yfio;
PDBTitle: crystal structure of rhodothermus marinus bamd
88c1na3A_
not modelled 99.1 24 PDB header:de novo protein
Chain: A: PDB Molecule:designed protein ctpr2;
PDBTitle: design of stable alpha-helical arrays from an idealized tpr2 motif
89d1pc2a_
not modelled 99.1 7 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
90d2hr2a1
not modelled 99.0 13 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:CT2138-like
91c2if4A_
not modelled 99.0 10 PDB header:signaling protein
Chain: A: PDB Molecule:atfkbp42;
PDBTitle: crystal structure of a multi-domain immunophilin from2 arabidopsis thaliana
92c2xm6A_
not modelled 99.0 10 PDB header:unknown function
Chain: A: PDB Molecule:protein corresponding to locus c5321 from cft073 e.coli
PDBTitle: crystal structure of the protein corresponding to locus c5321 from2 cft073 e.coli strain
93c2kcvA_
not modelled 99.0 19 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:tetratricopeptide repeat domain protein;
PDBTitle: solution nmr structure of tetratricopeptide repeat domain2 protein sru_0103 from salinibacter ruber, northeast3 structural genomics consortium (nesg) target srr115c
94c3k25B_
not modelled 99.0 15 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:slr1438 protein;
PDBTitle: crystal structure of slr1438 protein from synechocystis sp. pcc 6803,2 northeast structural genomics consortium target sgr112
95c3fflC_
not modelled 99.0 12 PDB header:cell cycle
Chain: C: PDB Molecule:anaphase-promoting complex subunit 7;
PDBTitle: crystal structure of the n-terminal domain of anaphase-2 promoting complex subunit 7
96d1zbpa1
not modelled 98.9 11 Fold:ImpE-like
Superfamily:ImpE-like
Family:ImpE-like
97c3dcdA_
not modelled 98.9 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:galactose mutarotase related enzyme;
PDBTitle: x-ray structure of the galactose mutarotase related enzyme q5fkd7 from2 lactobacillus acidophilus at the resolution 1.9a. northeast3 structural genomics consortium target lar33.
98c3ty1B_
not modelled 98.9 14 PDB header:isomerase
Chain: B: PDB Molecule:hypothetical aldose 1-epimerase;
PDBTitle: crystal structure of a hypothetical aldose 1-epimerase (kpn_04629)2 from klebsiella pneumoniae subsp. pneumoniae mgh 78578 at 1.90 a3 resolution
99c2l6jA_
not modelled 98.8 15 PDB header:protein binding
Chain: A: PDB Molecule:tpr repeat-containing protein associated with hsp90;
PDBTitle: tah1 complexed by meevd
100c3n71A_
not modelled 98.8 9 PDB header:transcription
Chain: A: PDB Molecule:histone lysine methyltransferase smyd1;
PDBTitle: crystal structure of cardiac specific histone methyltransferase smyd1
101c2avpA_
not modelled 98.8 25 PDB header:de novo protein
Chain: A: PDB Molecule:synthetic consensus tpr protein;
PDBTitle: crystal structure of an 8 repeat consensus tpr superhelix
102d1tjca_
not modelled 98.8 13 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
103d1y8ma1
not modelled 98.7 10 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
104d1z45a1
not modelled 98.6 12 Fold:Supersandwich
Superfamily:Galactose mutarotase-like
Family:Aldose 1-epimerase (mutarotase)
105c2kc7A_
not modelled 98.5 14 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:bfr218_protein;
PDBTitle: solution nmr structure of bacteroides fragilis protein2 bf1650. northeast structural genomics consortium target3 bfr218
106d2ff4a2
not modelled 98.5 13 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:BTAD-like
107d1ouva_
not modelled 98.5 12 Fold:alpha-alpha superhelix
Superfamily:HCP-like
Family:HCP-like
108c2qfcB_
not modelled 98.4 8 PDB header:transcription regulation
Chain: B: PDB Molecule:plcr protein;
PDBTitle: crystal structure of bacillus thuringiensis plcr complexed with papr
109c1ygaA_
not modelled 98.4 12 PDB header:isomerase
Chain: A: PDB Molecule:hypothetical 37.9 kda protein in bio3-hxt17
PDBTitle: crystal structure of saccharomyces cerevisiae yn9a protein,2 new york structural genomics consortium
110d2pqrb1
not modelled 98.3 12 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
111c3beeB_
not modelled 98.3 10 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative yfre protein;
PDBTitle: crystal structure of putative yfre protein from vibrio2 parahaemolyticus
112c3qwvA_
not modelled 98.3 10 PDB header:transferase
Chain: A: PDB Molecule:set and mynd domain-containing protein 2;
PDBTitle: crystal structure of histone lysine methyltransferase smyd2 in complex2 with the cofactor product adohcy
113c3e4bD_
not modelled 98.3 10 PDB header:protein binding
Chain: D: PDB Molecule:algk;
PDBTitle: crystal structure of algk from pseudomonas fluorescens wcs374r
114c3q3hA_
not modelled 98.3 6 PDB header:transferase
Chain: A: PDB Molecule:hmw1c-like glycosyltransferase;
PDBTitle: crystal structure of the actinobacillus pleuropneumoniae hmw1c2 glycosyltransferase in complex with udp-glc
115d1nsza_
not modelled 98.3 12 Fold:Supersandwich
Superfamily:Galactose mutarotase-like
Family:Aldose 1-epimerase (mutarotase)
116d1jova_
not modelled 98.2 8 Fold:Supersandwich
Superfamily:Galactose mutarotase-like
Family:Hypothetical protein HI1317
117c2cisA_
not modelled 98.2 17 PDB header:isomerase
Chain: A: PDB Molecule:hexose-6-phosphate mutarotase;
PDBTitle: structure-based functional annotation: yeast ymr099c codes2 for a d-hexose-6-phosphate mutarotase. complex with3 tagatose-6-phosphate
118c3mekA_
not modelled 98.2 13 PDB header:transferase
Chain: A: PDB Molecule:set and mynd domain-containing protein 3;
PDBTitle: crystal structure of human histone-lysine n-2 methyltransferase smyd3 in complex with s-adenosyl-l-3 methionine
119c3txmA_
not modelled 98.2 12 PDB header:hydrolase, protein binding
Chain: A: PDB Molecule:26s proteasome regulatory complex subunit p42b;
PDBTitle: crystal structure of rpn6 from drosophila melanogaster, gd(3+) complex
120c3imhB_
not modelled 98.1 15 PDB header:isomerase
Chain: B: PDB Molecule:galactose-1-epimerase;
PDBTitle: crystal structure of galactose 1-epimerase from lactobacillus2 acidophilus ncfm

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0