Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0AB58
DateThu Jan 5 11:14:41 GMT 2012
Unique Job ID36658b3e37f864ba

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1w3ba_
Top template information
Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
Confidence and coverage
Confidence: 99.9% Coverage: 83%
321 residues ( 83% of your sequence) have been modelled with 99.9% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
383 residues ( 98%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MLELLFLLLPVAAAYGWYMGRRSAQQNKQDEANRLSRDYVAGVNFLLSNQQDKAVDLFLD
Secondary structure 
SS confidence 
Disorder  ???
???
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  MLKEDTGTVEAHLTLGNLFRSRGEVDRAIRIHQTLMESASLTYEQRLLAIQQLGRDYMAA
Secondary structure 
SS confidence 
Disorder 
??????
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  GLYDRAEDMFNQLTDETDFRIGALQQLLQIYQATSEWQKAIDVAERLVKLGKDKQRVEIA
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  HFYCELALQHMASDDLDRAMTLLKKGAAADKNSARVSIMMGRVFMAKGEYAKAVESLQRV
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  ISQDRELVSETLEMLQTCYQQLGKTAEWAEFLQRAVEENTGADAELMLADIIEARDGSEA
Secondary structure 
SS confidence 
Disorder 
??
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  AQVYITRQLQRHPTMRVFHKLMDYHLNEAEEGRAKESLMVLRDMVGEKVRSKPRYRCQKC
Secondary structure 
SS confidence 
Disorder 
?????
?
?
Disorder confidence 
 
   .........370.........380.........
Sequence  GFTAYTLYWHCPSCRAWSTIKPIRGLDGL
Secondary structure 
SS confidence 
Disorder 
?
?
???????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1w3b chain A

3D model

Region: 5 - 330
Aligned: 321
Modelled: 326
Confidence: 99.9%
Identity: 14%
Fold: alpha-alpha superhelix
Superfamily: TPR-like
Family: Tetratricopeptide repeat (TPR)

Phyre2

PDB 2xpi chain A

3D model

Region: 15 - 327
Aligned: 304
Modelled: 313
Confidence: 99.9%
Identity: 13%
PDB header:cell cycle
Chain: A: PDB Molecule:anaphase-promoting complex subunit cut9;
PDBTitle: crystal structure of apc/c hetero-tetramer cut9-hcn1

Phyre2

PDB 3ieg chain B

3D model

Region: 34 - 333
Aligned: 296
Modelled: 300
Confidence: 99.9%
Identity: 14%
PDB header:chaperone
Chain: B: PDB Molecule:dnaj homolog subfamily c member 3;
PDBTitle: crystal structure of p58(ipk) tpr domain at 2.5 a

Phyre2

PDB 1fch chain B

3D model

Region: 30 - 311
Aligned: 275
Modelled: 282
Confidence: 99.9%
Identity: 15%
PDB header:signaling protein
Chain: B: PDB Molecule:peroxisomal targeting signal 1 receptor;
PDBTitle: crystal structure of the pts1 complexed to the tpr region2 of human pex5

Phyre2

PDB 3fp4 chain A

3D model

Region: 39 - 325
Aligned: 282
Modelled: 287
Confidence: 99.9%
Identity: 16%
PDB header:transport protein
Chain: A: PDB Molecule:tpr repeat-containing protein yhr117w;
PDBTitle: crystal structure of tom71 complexed with ssa1 c-terminal2 fragment

Phyre2

PDB 2y4t chain A

3D model

Region: 37 - 329
Aligned: 289
Modelled: 293
Confidence: 99.9%
Identity: 13%
PDB header:chaperone
Chain: A: PDB Molecule:dnaj homolog subfamily c member 3;
PDBTitle: crystal structure of the human co-chaperone p58(ipk)

Phyre2

PDB 3cvp chain A

3D model

Region: 34 - 313
Aligned: 264
Modelled: 280
Confidence: 99.9%
Identity: 11%
PDB header:transport protein
Chain: A: PDB Molecule:peroxisome targeting signal 1 receptor pex5;
PDBTitle: structure of peroxisomal targeting signal 1 (pts1) binding2 domain of trypanosoma brucei peroxin 5 (tbpex5)complexed3 to pts1 peptide (10-skl)

Phyre2

PDB 1fch chain A

3D model

Region: 34 - 311
Aligned: 270
Modelled: 278
Confidence: 99.9%
Identity: 16%
Fold: alpha-alpha superhelix
Superfamily: TPR-like
Family: Tetratricopeptide repeat (TPR)

Phyre2

PDB 2gw1 chain A

3D model

Region: 37 - 344
Aligned: 303
Modelled: 308
Confidence: 99.9%
Identity: 19%
PDB header:protein transport
Chain: A: PDB Molecule:mitochondrial precursor proteins import receptor;
PDBTitle: crystal structure of the yeast tom70

Phyre2

PDB 2ooe chain A domain 1

3D model

Region: 25 - 350
Aligned: 322
Modelled: 326
Confidence: 99.9%
Identity: 14%
Fold: alpha-alpha superhelix
Superfamily: TPR-like
Family: HAT/Suf repeat

Phyre2

PDB 1dce chain A domain 1

3D model

Region: 42 - 328
Aligned: 273
Modelled: 282
Confidence: 99.9%
Identity: 8%
Fold: alpha-alpha superhelix
Superfamily: Protein prenylyltransferase
Family: Protein prenylyltransferase

Phyre2

PDB 3hym chain B

3D model

Region: 34 - 331
Aligned: 290
Modelled: 298
Confidence: 99.9%
Identity: 11%
PDB header:cell cycle, ligase
Chain: B: PDB Molecule:cell division cycle protein 16 homolog;
PDBTitle: insights into anaphase promoting complex tpr subdomain2 assembly from a cdc26-apc6 structure

Phyre2

PDB 1hz4 chain A

3D model

Region: 26 - 351
Aligned: 326
Modelled: 326
Confidence: 99.9%
Identity: 14%
Fold: alpha-alpha superhelix
Superfamily: TPR-like
Family: Transcription factor MalT domain III

Phyre2

PDB 2uy1 chain A

3D model

Region: 33 - 340
Aligned: 307
Modelled: 308
Confidence: 99.8%
Identity: 12%
PDB header:rna-binding protein
Chain: A: PDB Molecule:cleavage stimulation factor 77;
PDBTitle: crystal structure of cstf-77

Phyre2

PDB 3mkr chain A

3D model

Region: 40 - 325
Aligned: 268
Modelled: 279
Confidence: 99.8%
Identity: 13%
PDB header:transport protein
Chain: A: PDB Molecule:coatomer subunit epsilon;
PDBTitle: crystal structure of yeast alpha/epsilon-cop subcomplex of the copi2 vesicular coat

Phyre2

PDB 1qsa chain A domain 1

3D model

Region: 2 - 340
Aligned: 334
Modelled: 339
Confidence: 99.8%
Identity: 12%
Fold: alpha-alpha superhelix
Superfamily: Bacterial muramidases
Family: Bacterial muramidases

Phyre2

PDB 3dra chain A

3D model

Region: 39 - 320
Aligned: 245
Modelled: 245
Confidence: 99.8%
Identity: 9%
PDB header:transferase
Chain: A: PDB Molecule:protein
PDBTitle: candida albicans protein geranylgeranyltransferase-i2 complexed with ggpp

Phyre2

PDB 2ho1 chain B

3D model

Region: 31 - 288
Aligned: 216
Modelled: 221
Confidence: 99.8%
Identity: 17%
PDB header:protein binding
Chain: B: PDB Molecule:type 4 fimbrial biogenesis protein pilf;
PDBTitle: functional characterization of pseudomonas aeruginosa pilf

Phyre2

PDB 2vq2 chain A

3D model

Region: 38 - 288
Aligned: 211
Modelled: 214
Confidence: 99.8%
Identity: 16%
PDB header:structural protein
Chain: A: PDB Molecule:putative fimbrial biogenesis and twitching
PDBTitle: crystal structure of pilw, widely conserved type iv pilus2 biogenesis factor

Phyre2

PDB 3q75 chain A

3D model

Region: 39 - 326
Aligned: 255
Modelled: 257
Confidence: 99.8%
Identity: 10%
PDB header:transferase
Chain: A: PDB Molecule:farnesyltransferase alpha subunit;
PDBTitle: cryptococcus neoformans protein farnesyltransferase in complex with2 fpt-ii and tkcvvm peptide

Phyre2

PDB 2gmg chain A domain 1

3D model

Region: 329 - 382
Aligned: 53
Modelled: 53
Confidence: 96.7%
Identity: 25%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Family: PF0610-like

Phyre2

PDB 2kdx chain A

3D model

Region: 353 - 387
Aligned: 34
Modelled: 34
Confidence: 96.4%
Identity: 18%
PDB header:metal-binding protein
Chain: A: PDB Molecule:hydrogenase/urease nickel incorporation protein
PDBTitle: solution structure of hypa protein

Phyre2

PDB 3a44 chain D

3D model

Region: 353 - 387
Aligned: 34
Modelled: 34
Confidence: 96.3%
Identity: 18%
PDB header:metal binding protein
Chain: D: PDB Molecule:hydrogenase nickel incorporation protein hypa;
PDBTitle: crystal structure of hypa in the dimeric form

Phyre2

PDB 1dx8 chain A

3D model

Region: 351 - 385
Aligned: 35
Modelled: 35
Confidence: 94.0%
Identity: 26%
Fold: Rubredoxin-like
Superfamily: Rubredoxin-like
Family: Rubredoxin

Phyre2
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d1w3ba_
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c2xpiA_
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c3iegB_
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c1fchB_
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c3fp4A_
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c2y4tA_
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c3cvpA_
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d1fcha_
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c2gw1A_
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d2ooea1
11
d1dcea1
12
c3hymB_
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d1hz4a_
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c2uy1A_
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c3mkrA_
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d1qsaa1
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c3draA_
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c2ho1B_
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c2vq2A_
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c3q75A_
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d2gmga1
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c2kdxA_
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c3a44D_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1w3ba_
99.9 14 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
2c2xpiA_
99.9 13 PDB header:cell cycle
Chain: A: PDB Molecule:anaphase-promoting complex subunit cut9;
PDBTitle: crystal structure of apc/c hetero-tetramer cut9-hcn1
3c3iegB_
99.9 14 PDB header:chaperone
Chain: B: PDB Molecule:dnaj homolog subfamily c member 3;
PDBTitle: crystal structure of p58(ipk) tpr domain at 2.5 a
4c1fchB_
99.9 15 PDB header:signaling protein
Chain: B: PDB Molecule:peroxisomal targeting signal 1 receptor;
PDBTitle: crystal structure of the pts1 complexed to the tpr region2 of human pex5
5c3fp4A_
99.9 16 PDB header:transport protein
Chain: A: PDB Molecule:tpr repeat-containing protein yhr117w;
PDBTitle: crystal structure of tom71 complexed with ssa1 c-terminal2 fragment
6c2y4tA_
99.9 13 PDB header:chaperone
Chain: A: PDB Molecule:dnaj homolog subfamily c member 3;
PDBTitle: crystal structure of the human co-chaperone p58(ipk)
7c3cvpA_
99.9 11 PDB header:transport protein
Chain: A: PDB Molecule:peroxisome targeting signal 1 receptor pex5;
PDBTitle: structure of peroxisomal targeting signal 1 (pts1) binding2 domain of trypanosoma brucei peroxin 5 (tbpex5)complexed3 to pts1 peptide (10-skl)
8d1fcha_
99.9 16 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
9c2gw1A_
99.9 19 PDB header:protein transport
Chain: A: PDB Molecule:mitochondrial precursor proteins import receptor;
PDBTitle: crystal structure of the yeast tom70
10d2ooea1
99.9 14 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:HAT/Suf repeat
11d1dcea1
99.9 8 Fold:alpha-alpha superhelix
Superfamily:Protein prenylyltransferase
Family:Protein prenylyltransferase
12c3hymB_
99.9 11 PDB header:cell cycle, ligase
Chain: B: PDB Molecule:cell division cycle protein 16 homolog;
PDBTitle: insights into anaphase promoting complex tpr subdomain2 assembly from a cdc26-apc6 structure
13d1hz4a_
99.9 14 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Transcription factor MalT domain III
14c2uy1A_
99.8 12 PDB header:rna-binding protein
Chain: A: PDB Molecule:cleavage stimulation factor 77;
PDBTitle: crystal structure of cstf-77
15c3mkrA_
99.8 13 PDB header:transport protein
Chain: A: PDB Molecule:coatomer subunit epsilon;
PDBTitle: crystal structure of yeast alpha/epsilon-cop subcomplex of the copi2 vesicular coat
16d1qsaa1
99.8 12 Fold:alpha-alpha superhelix
Superfamily:Bacterial muramidases
Family:Bacterial muramidases
17c3draA_
99.8 9 PDB header:transferase
Chain: A: PDB Molecule:protein
PDBTitle: candida albicans protein geranylgeranyltransferase-i2 complexed with ggpp
18c2ho1B_
99.8 17 PDB header:protein binding
Chain: B: PDB Molecule:type 4 fimbrial biogenesis protein pilf;
PDBTitle: functional characterization of pseudomonas aeruginosa pilf
19c2vq2A_
99.8 16 PDB header:structural protein
Chain: A: PDB Molecule:putative fimbrial biogenesis and twitching
PDBTitle: crystal structure of pilw, widely conserved type iv pilus2 biogenesis factor
20c3q75A_
99.8 10 PDB header:transferase
Chain: A: PDB Molecule:farnesyltransferase alpha subunit;
PDBTitle: cryptococcus neoformans protein farnesyltransferase in complex with2 fpt-ii and tkcvvm peptide
21c3pe3D_
not modelled 99.8 15 PDB header:transferase
Chain: D: PDB Molecule:udp-n-acetylglucosamine--peptide n-
PDBTitle: structure of human o-glcnac transferase and its complex with a peptide2 substrate
22d1xnfa_
not modelled 99.7 12 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
23c3mv3B_
not modelled 99.7 7 PDB header:protein transport
Chain: B: PDB Molecule:coatomer subunit epsilon;
PDBTitle: crystal structure of a-cop in complex with e-cop
24d1d8da_
not modelled 99.7 11 Fold:alpha-alpha superhelix
Superfamily:Protein prenylyltransferase
Family:Protein prenylyltransferase
25d2h6fa1
not modelled 99.7 10 Fold:alpha-alpha superhelix
Superfamily:Protein prenylyltransferase
Family:Protein prenylyltransferase
26c2q7fA_
not modelled 99.7 19 PDB header:protein binding
Chain: A: PDB Molecule:yrrb protein;
PDBTitle: crystal structure of yrrb: a tpr protein with an unusual peptide-2 binding site
27c1tnoI_
not modelled 99.7 11 PDB header:transferase
Chain: I: PDB Molecule:geranylgeranyltransferase type i alpha subunit;
PDBTitle: rat protein geranylgeranyltransferase type-i complexed with2 a ggpp analog and a kkksktkcvim peptide derived from k-3 ras4b
28c3urzB_
not modelled 99.7 14 PDB header:protein binding
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a hypothetical protein (bacova_03105) from2 bacteroides ovatus atcc 8483 at 2.19 a resolution
29c3q15A_
not modelled 99.7 14 PDB header:hydrolase/kinase
Chain: A: PDB Molecule:response regulator aspartate phosphatase h;
PDBTitle: crystal structure of raph complexed with spo0f
30c2pl2A_
not modelled 99.7 21 PDB header:protein binding
Chain: A: PDB Molecule:hypothetical conserved protein ttc0263;
PDBTitle: crystal structure of ttc0263: a thermophilic tpr protein in thermus2 thermophilus hb27
31c3sf4B_
not modelled 99.7 17 PDB header:signaling protein/protein binding
Chain: B: PDB Molecule:g-protein-signaling modulator 2;
PDBTitle: crystal structure of the complex between the conserved cell polarity2 proteins inscuteable and lgn
32c2ifuA_
not modelled 99.6 13 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:gamma-snap;
PDBTitle: crystal structure of a gamma-snap from danio rerio
33c3as5A_
not modelled 99.6 18 PDB header:protein binding
Chain: A: PDB Molecule:mama;
PDBTitle: mama amb-1 p212121
34d2c2la1
not modelled 99.5 9 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
35d1hh8a_
not modelled 99.5 13 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
36c2r5sB_
not modelled 99.5 19 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein vp0806;
PDBTitle: the crystal structure of a domain of protein vp0806 (unknown function)2 from vibrio parahaemolyticus rimd 2210633
37c3qkyA_
not modelled 99.5 13 PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane assembly lipoprotein yfio;
PDBTitle: crystal structure of rhodothermus marinus bamd
38c1xi4D_
not modelled 99.5 13 PDB header:endocytosis/exocytosis
Chain: D: PDB Molecule:clathrin heavy chain;
PDBTitle: clathrin d6 coat
39c3gw4B_
not modelled 99.5 20 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of uncharacterized protein from deinococcus2 radiodurans. northeast structural genomics consortium target drr162b.
40c1wao4_
not modelled 99.4 7 PDB header:hydrolase
Chain: 4: PDB Molecule:serine/threonine protein phosphatase 5;
PDBTitle: pp5 structure
41c2c2lD_
not modelled 99.4 8 PDB header:chaperone
Chain: D: PDB Molecule:carboxy terminus of hsp70-interacting protein;
PDBTitle: crystal structure of the chip u-box e3 ubiquitin ligase
42c2yhcA_
not modelled 99.4 9 PDB header:membrane protein
Chain: A: PDB Molecule:upf0169 lipoprotein yfio;
PDBTitle: structure of bamd from e. coli
43d2onda1
not modelled 99.4 9 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:HAT/Suf repeat
44c3ly8A_
not modelled 99.4 13 PDB header:signaling protein
Chain: A: PDB Molecule:transcriptional activator cadc;
PDBTitle: crystal structure of mutant d471e of the periplasmic domain of cadc
45c2hyzA_
not modelled 99.4 24 PDB header:de novo protein
Chain: A: PDB Molecule:synthetic consensus tpr protein;
PDBTitle: crystal structure of an 8 repeat consensus tpr superhelix2 (orthorombic crystal form)
46c3nf1A_
not modelled 99.3 9 PDB header:motor protein, transport protein
Chain: A: PDB Molecule:kinesin light chain 1;
PDBTitle: crystal structure of the tpr domain of kinesin light chain 1
47d1qqea_
not modelled 99.3 10 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
48c1slyA_
not modelled 99.3 10 PDB header:glycosyltransferase
Chain: A: PDB Molecule:70-kda soluble lytic transglycosylase;
PDBTitle: complex of the 70-kda soluble lytic transglycosylase with2 bulgecin a
49c2xcbA_
not modelled 99.3 16 PDB header:protein binding
Chain: A: PDB Molecule:regulatory protein pcrh;
PDBTitle: crystal structure of pcrh in complex with the chaperone2 binding region of popd
50c2e2eA_
not modelled 99.3 12 PDB header:lyase
Chain: A: PDB Molecule:formate-dependent nitrite reductase complex nrfg subunit;
PDBTitle: tpr domain of nrfg mediates the complex formation between heme lyase2 and formate-dependent nitrite reductase in escherichia coli o157:h7
51c3q49B_
not modelled 99.3 9 PDB header:ligase/chaperone
Chain: B: PDB Molecule:stip1 homology and u box-containing protein 1;
PDBTitle: crystal structure of the tpr domain of chip complexed with hsp70-c2 peptide
52c3gyzB_
not modelled 99.3 13 PDB header:chaperone
Chain: B: PDB Molecule:chaperone protein ipgc;
PDBTitle: crystal structure of ipgc from shigella flexneri
53d1elwa_
not modelled 99.3 9 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
54c3qdnA_
not modelled 99.2 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative thioredoxin protein;
PDBTitle: putative thioredoxin protein from salmonella typhimurium
55d1hxia_
not modelled 99.2 12 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
56c2kckA_
not modelled 99.2 10 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:tpr repeat;
PDBTitle: nmr solution structure of the northeast structural genomics2 consortium (nesg) target mrr121a
57c2vsnB_
not modelled 99.2 10 PDB header:transferase
Chain: B: PDB Molecule:xcogt;
PDBTitle: structure and topological arrangement of an o-glcnac2 transferase homolog: insight into molecular control of3 intracellular glycosylation
58c2vyiA_
not modelled 99.2 9 PDB header:chaperone
Chain: A: PDB Molecule:sgta protein;
PDBTitle: crystal structure of the tpr domain of human sgt
59c2xevB_
not modelled 99.2 17 PDB header:metal binding
Chain: B: PDB Molecule:ybgf;
PDBTitle: crystal structure of the tpr domain of xanthomonas2 campestris ybgf
60c3ceqB_
not modelled 99.2 15 PDB header:motor protein, transport protein
Chain: B: PDB Molecule:kinesin light chain 2;
PDBTitle: the tpr domain of human kinesin light chain 2 (hklc2)
61c3sz7A_
not modelled 99.2 12 PDB header:chaperone regulator
Chain: A: PDB Molecule:hsc70 cochaperone (sgt);
PDBTitle: crystal structure of the sgt2 tpr domain from aspergillus fumigatus
62d2buga1
not modelled 99.1 7 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
63d1elra_
not modelled 99.1 15 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
64d1a17a_
not modelled 99.1 13 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
65d1nzna_
not modelled 99.1 11 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
66d1iyga_
not modelled 99.1 12 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
67c2l6jA_
not modelled 99.1 14 PDB header:protein binding
Chain: A: PDB Molecule:tpr repeat-containing protein associated with hsp90;
PDBTitle: tah1 complexed by meevd
68c2dbaA_
not modelled 99.0 13 PDB header:structural protein
Chain: A: PDB Molecule:smooth muscle cell associated protein-1, isoform
PDBTitle: the solution structure of the tetratrico peptide repeat of2 human smooth muscle cell associated protein-1, isoform 2
69d1zu2a1
not modelled 99.0 17 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
70c3q3hA_
not modelled 99.0 7 PDB header:transferase
Chain: A: PDB Molecule:hmw1c-like glycosyltransferase;
PDBTitle: crystal structure of the actinobacillus pleuropneumoniae hmw1c2 glycosyltransferase in complex with udp-glc
71c1ihgA_
not modelled 99.0 15 PDB header:isomerase
Chain: A: PDB Molecule:cyclophilin 40;
PDBTitle: bovine cyclophilin 40, monoclinic form
72c3rkvA_
not modelled 99.0 18 PDB header:isomerase
Chain: A: PDB Molecule:putative peptidylprolyl isomerase;
PDBTitle: c-terminal domain of protein c56c10.10, a putative peptidylprolyl2 isomerase, from caenorhabditis elegans
73d1pc2a_
not modelled 99.0 14 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
74c2katA_
not modelled 99.0 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: solution structure of protein bpp2914 from bordetella2 parapertussis. northeast structural genomics consortium3 target bpr206
75c2kcvA_
not modelled 99.0 19 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:tetratricopeptide repeat domain protein;
PDBTitle: solution nmr structure of tetratricopeptide repeat domain2 protein sru_0103 from salinibacter ruber, northeast3 structural genomics consortium (nesg) target srr115c
76d1kt1a1
not modelled 98.9 12 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
77d1p5qa1
not modelled 98.9 14 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
78d2hr2a1
not modelled 98.9 12 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:CT2138-like
79c1kt0A_
not modelled 98.9 11 PDB header:isomerase
Chain: A: PDB Molecule:51 kda fk506-binding protein;
PDBTitle: structure of the large fkbp-like protein, fkbp51, involved in steroid2 receptor complexes
80c1na3A_
not modelled 98.9 28 PDB header:de novo protein
Chain: A: PDB Molecule:designed protein ctpr2;
PDBTitle: design of stable alpha-helical arrays from an idealized tpr2 motif
81c3k9iA_
not modelled 98.9 13 PDB header:protein binding
Chain: A: PDB Molecule:bh0479 protein;
PDBTitle: crystal structure of putative protein binding protein (np_241345.1)2 from bacillus halodurans at 2.71 a resolution
82c2kc7A_
not modelled 98.9 14 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:bfr218_protein;
PDBTitle: solution nmr structure of bacteroides fragilis protein2 bf1650. northeast structural genomics consortium target3 bfr218
83c2fbnA_
not modelled 98.9 15 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:70 kda peptidylprolyl isomerase, putative;
PDBTitle: plasmodium falciparum putative fk506-binding protein2 pfl2275c, c-terminal tpr-containing domain
84d2fbna1
not modelled 98.9 15 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
85c2vgxA_
not modelled 98.8 10 PDB header:chaperone
Chain: A: PDB Molecule:chaperone sycd;
PDBTitle: structure of the yersinia enterocolitica type iii secretion2 translocator chaperone sycd
86c2avpA_
not modelled 98.8 25 PDB header:de novo protein
Chain: A: PDB Molecule:synthetic consensus tpr protein;
PDBTitle: crystal structure of an 8 repeat consensus tpr superhelix
87c1qz2B_
not modelled 98.8 14 PDB header:isomerase/chaperone
Chain: B: PDB Molecule:fk506-binding protein 4;
PDBTitle: crystal structure of fkbp52 c-terminal domain complex with2 the c-terminal peptide meevd of hsp90
88d1zbpa1
not modelled 98.8 13 Fold:ImpE-like
Superfamily:ImpE-like
Family:ImpE-like
89d1ihga1
not modelled 98.8 15 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
90c1ltxA_
not modelled 98.7 12 PDB header:transferase/protein binding
Chain: A: PDB Molecule:rab geranylgeranyltransferase alpha subunit;
PDBTitle: structure of rab escort protein-1 in complex with rab2 geranylgeranyl transferase and isoprenoid
91c3fflC_
not modelled 98.6 10 PDB header:cell cycle
Chain: C: PDB Molecule:anaphase-promoting complex subunit 7;
PDBTitle: crystal structure of the n-terminal domain of anaphase-2 promoting complex subunit 7
92c2if4A_
not modelled 98.6 11 PDB header:signaling protein
Chain: A: PDB Molecule:atfkbp42;
PDBTitle: crystal structure of a multi-domain immunophilin from2 arabidopsis thaliana
93c3beeB_
not modelled 98.6 17 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative yfre protein;
PDBTitle: crystal structure of putative yfre protein from vibrio2 parahaemolyticus
94d1tjca_
not modelled 98.5 15 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
95c2xm6A_
not modelled 98.5 12 PDB header:unknown function
Chain: A: PDB Molecule:protein corresponding to locus c5321 from cft073 e.coli
PDBTitle: crystal structure of the protein corresponding to locus c5321 from2 cft073 e.coli strain
96d1ouva_
not modelled 98.4 10 Fold:alpha-alpha superhelix
Superfamily:HCP-like
Family:HCP-like
97d1y8ma1
not modelled 98.4 17 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
98c3n71A_
not modelled 98.3 9 PDB header:transcription
Chain: A: PDB Molecule:histone lysine methyltransferase smyd1;
PDBTitle: crystal structure of cardiac specific histone methyltransferase smyd1
99d2ff4a2
not modelled 98.1 11 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:BTAD-like
100d2pqrb1
not modelled 98.0 18 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
101c3e4bD_
not modelled 97.9 14 PDB header:protein binding
Chain: D: PDB Molecule:algk;
PDBTitle: crystal structure of algk from pseudomonas fluorescens wcs374r
102c3lvhA_
not modelled 97.9 13 PDB header:structural protein
Chain: A: PDB Molecule:clathrin heavy chain 1;
PDBTitle: crystal structure of a clathrin heavy chain and clathrin light chain2 complex
103c3mekA_
not modelled 97.6 9 PDB header:transferase
Chain: A: PDB Molecule:set and mynd domain-containing protein 3;
PDBTitle: crystal structure of human histone-lysine n-2 methyltransferase smyd3 in complex with s-adenosyl-l-3 methionine
104c3qwvA_
not modelled 97.5 9 PDB header:transferase
Chain: A: PDB Molecule:set and mynd domain-containing protein 2;
PDBTitle: crystal structure of histone lysine methyltransferase smyd2 in complex2 with the cofactor product adohcy
105c3oxgA_
not modelled 97.4 9 PDB header:transferase
Chain: A: PDB Molecule:set and mynd domain-containing protein 3;
PDBTitle: human lysine methyltransferase smyd3 in complex with adohcy (form iii)
106c2qfcB_
not modelled 96.9 10 PDB header:transcription regulation
Chain: B: PDB Molecule:plcr protein;
PDBTitle: crystal structure of bacillus thuringiensis plcr complexed with papr
107d2gmga1
96.7 25 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:PF0610-like
108c2lahA_
not modelled 96.6 11 PDB header:cell cycle, apoptosis
Chain: A: PDB Molecule:mitotic checkpoint serine/threonine-protein kinase bub1;
PDBTitle: solution nmr structure of mitotic checkpoint serine/threonine-protein2 kinase bub1 n-terminal domain from homo sapiens, northeast structural3 genomics consortium target hr5460a (methods development)
109c2kdxA_
96.4 18 PDB header:metal-binding protein
Chain: A: PDB Molecule:hydrogenase/urease nickel incorporation protein
PDBTitle: solution structure of hypa protein
110c3txmA_
not modelled 96.4 11 PDB header:hydrolase, protein binding
Chain: A: PDB Molecule:26s proteasome regulatory complex subunit p42b;
PDBTitle: crystal structure of rpn6 from drosophila melanogaster, gd(3+) complex
111d1iipa1
not modelled 96.3 19 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
112c3eslA_
not modelled 96.3 11 PDB header:cell cycle
Chain: A: PDB Molecule:checkpoint serine/threonine-protein kinase bub1;
PDBTitle: crystal structure of the conserved n-terminal domain of the2 mitotic checkpoint component bub1
113c3a44D_
96.3 18 PDB header:metal binding protein
Chain: D: PDB Molecule:hydrogenase nickel incorporation protein hypa;
PDBTitle: crystal structure of hypa in the dimeric form
114c2ff4B_
not modelled 96.1 17 PDB header:transcription
Chain: B: PDB Molecule:probable regulatory protein embr;
PDBTitle: mycobacterium tuberculosis embr in complex with low affinity2 phosphopeptide
115c3mv2A_
not modelled 95.4 9 PDB header:protein transport
Chain: A: PDB Molecule:coatomer subunit alpha;
PDBTitle: crystal structure of a-cop in complex with e-cop
116c3rjvA_
not modelled 95.3 11 PDB header:protein binding
Chain: A: PDB Molecule:putative sel1 repeat protein;
PDBTitle: crystal structure of a putative sel1 repeat protein (kpn_04481) from2 klebsiella pneumoniae subsp. pneumoniae at 1.65 a resolution
117c2hr5B_
not modelled 95.2 17 PDB header:metal binding protein
Chain: B: PDB Molecule:rubrerythrin;
PDBTitle: pf1283- rubrerythrin from pyrococcus furiosus iron bound form
118d1dx8a_
94.0 26 Fold:Rubredoxin-like
Superfamily:Rubredoxin-like
Family:Rubredoxin
119c2wviA_
not modelled 94.0 10 PDB header:transferase
Chain: A: PDB Molecule:mitotic checkpoint serine/threonine-protein
PDBTitle: crystal structure of the n-terminal domain of bubr1
120c1yuzB_
not modelled 94.0 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:nigerythrin;
PDBTitle: partially reduced state of nigerythrin

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0