Email l.a.kelley@imperial.ac.uk Description P08997 Date Thu Jan 5 11:01:45 GMT 2012 Unique Job ID 1fbe5d9204cf41b3

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3cuzA_ 100.0 100 PDB header:transferase Chain: A: PDB Molecule:malate synthase a; PDBTitle: atomic resolution structures of escherichia coli and2 bacillis anthracis malate synthase a: comparison with3 isoform g and implications for structure based drug design 2 c3cuxA_ 100.0 55 PDB header:transferase Chain: A: PDB Molecule:malate synthase; PDBTitle: atomic resolution structures of escherichia coli and2 bacillis anthracis malate synthase a: comparison with3 isoform g and implications for structure based drug design 3 d1n8ia_ 100.0 21 Fold:TIM beta/alpha-barrel Superfamily:Malate synthase G Family:Malate synthase G 4 d1d8ca_ 100.0 19 Fold:TIM beta/alpha-barrel Superfamily:Malate synthase G Family:Malate synthase G 5 c3pugA_ 100.0 17 PDB header:transferase Chain: A: PDB Molecule:malate synthase; PDBTitle: haloferax volcanii malate synthase native at 3mm glyoxylate 6 c3r4iB_ 100.0 17 PDB header:lyase Chain: B: PDB Molecule:citrate lyase; PDBTitle: crystal structure of a citrate lyase (bxe_b2899) from burkholderia2 xenovorans lb400 at 2.24 a resolution 7 c3qqwC_ 100.0 15 PDB header:lyase Chain: C: PDB Molecule:putative citrate lyase; PDBTitle: crystal structure of a hypothetical lyase (reut_b4148) from ralstonia2 eutropha jmp134 at 2.44 a resolution 8 c1sgjB_ 100.0 16 PDB header:lyase Chain: B: PDB Molecule:citrate lyase, beta subunit; PDBTitle: crystal structure of citrate lyase beta subunit 9 d1sgja_ 100.0 16 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:HpcH/HpaI aldolase 10 c1u5vA_ 100.0 20 PDB header:lyase Chain: A: PDB Molecule:cite; PDBTitle: structure of cite complexed with triphosphate group of atp2 form mycobacterium tuberculosis 11 d1u5ha_ 100.0 20 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:HpcH/HpaI aldolase 12 d1dxea_ 99.9 19 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:HpcH/HpaI aldolase 13 c2v5jB_ 99.8 20 PDB header:lyase Chain: B: PDB Molecule:2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; PDBTitle: apo class ii aldolase hpch 14 c1izcA_ 99.8 16 PDB header:lyase Chain: A: PDB Molecule:macrophomate synthase intermolecular diels-alderase; PDBTitle: crystal structure analysis of macrophomate synthase 15 d1izca_ 99.8 16 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:HpcH/HpaI aldolase 16 c2vwtA_ 99.8 18 PDB header:lyase Chain: A: PDB Molecule:yfau, 2-keto-3-deoxy sugar aldolase; PDBTitle: crystal structure of yfau, a metal ion dependent class ii2 aldolase from escherichia coli k12 - mg-pyruvate product3 complex 17 c3qz6A_ 99.7 19 PDB header:lyase Chain: A: PDB Molecule:hpch/hpai aldolase; PDBTitle: the crystal structure of hpch/hpai aldolase from desulfitobacterium2 hafniense dcb-2 18 d1e0ta2 99.7 22 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 19 d1a3xa2 99.6 19 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 20 d1pkla2 99.4 19 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 21 d2g50a2 not modelled 99.3 15 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 22 d1liua2 not modelled 99.3 19 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 23 c2hwgA_ not modelled 98.9 10 PDB header:transferase Chain: A: PDB Molecule:phosphoenolpyruvate-protein phosphotransferase; PDBTitle: structure of phosphorylated enzyme i of the2 phosphoenolpyruvate:sugar phosphotransferase system 24 c2hroA_ not modelled 98.8 10 PDB header:transferase Chain: A: PDB Molecule:phosphoenolpyruvate-protein phosphotransferase; PDBTitle: structure of the full-lenght enzyme i of the pts system from2 staphylococcus carnosus 25 c2bg5C_ not modelled 98.8 14 PDB header:transferase Chain: C: PDB Molecule:phosphoenolpyruvate-protein kinase; PDBTitle: crystal structure of the phosphoenolpyruvate-binding enzyme2 i-domain from the thermoanaerobacter tengcongensis pep:3 sugar phosphotransferase system (pts) 26 d1h6za1 not modelled 98.7 12 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate phosphate dikinase, C-terminal domain 27 d1vbga1 not modelled 98.6 18 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate phosphate dikinase, C-terminal domain 28 c1vbhA_ not modelled 98.6 17 PDB header:transferase Chain: A: PDB Molecule:pyruvate,orthophosphate dikinase; PDBTitle: pyruvate phosphate dikinase with bound mg-pep from maize 29 c1t5aB_ not modelled 98.4 18 PDB header:transferase Chain: B: PDB Molecule:pyruvate kinase, m2 isozyme; PDBTitle: human pyruvate kinase m2 30 c2vgbB_ not modelled 98.3 14 PDB header:transferase Chain: B: PDB Molecule:pyruvate kinase isozymes r/l; PDBTitle: human erythrocyte pyruvate kinase 31 c1aqfB_ not modelled 98.3 18 PDB header:transferase Chain: B: PDB Molecule:pyruvate kinase; PDBTitle: pyruvate kinase from rabbit muscle with mg, k, and l-2 phospholactate 32 c3khdC_ not modelled 98.3 20 PDB header:transferase Chain: C: PDB Molecule:pyruvate kinase; PDBTitle: crystal structure of pff1300w. 33 c1h6zA_ not modelled 98.3 13 PDB header:transferase Chain: A: PDB Molecule:pyruvate phosphate dikinase; PDBTitle: 3.0 a resolution crystal structure of glycosomal pyruvate2 phosphate dikinase from trypanosoma brucei 34 d1kbla1 not modelled 98.1 12 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate phosphate dikinase, C-terminal domain 35 c1e0tD_ not modelled 98.1 19 PDB header:phosphotransferase Chain: D: PDB Molecule:pyruvate kinase; PDBTitle: r292d mutant of e. coli pyruvate kinase 36 c1kblA_ not modelled 98.1 15 PDB header:transferase Chain: A: PDB Molecule:pyruvate phosphate dikinase; PDBTitle: pyruvate phosphate dikinase 37 c1a3wB_ not modelled 98.0 20 PDB header:transferase Chain: B: PDB Molecule:pyruvate kinase; PDBTitle: pyruvate kinase from saccharomyces cerevisiae complexed with fbp, pg,2 mn2+ and k+ 38 c3ma8A_ not modelled 98.0 18 PDB header:transferase Chain: A: PDB Molecule:pyruvate kinase; PDBTitle: crystal structure of cgd1_2040, a pyruvate kinase from cryptosporidium2 parvum 39 c1pklB_ not modelled 97.9 17 PDB header:transferase Chain: B: PDB Molecule:protein (pyruvate kinase); PDBTitle: the structure of leishmania pyruvate kinase 40 c2olsA_ not modelled 97.9 14 PDB header:transferase Chain: A: PDB Molecule:phosphoenolpyruvate synthase; PDBTitle: the crystal structure of the phosphoenolpyruvate synthase from2 neisseria meningitidis 41 c3e0vB_ not modelled 97.8 19 PDB header:transferase Chain: B: PDB Molecule:pyruvate kinase; PDBTitle: crystal structure of pyruvate kinase from leishmania mexicana in2 complex with sulphate ions 42 c2e28A_ not modelled 97.7 21 PDB header:transferase Chain: A: PDB Molecule:pyruvate kinase; PDBTitle: crystal structure analysis of pyruvate kinase from bacillus2 stearothermophilus 43 c3eoeC_ not modelled 97.7 18 PDB header:transferase Chain: C: PDB Molecule:pyruvate kinase; PDBTitle: crystal structure of pyruvate kinase from toxoplasma gondii, 55.m00007 44 c3t07D_ not modelled 97.6 20 PDB header:transferase/transferase inhibitor Chain: D: PDB Molecule:pyruvate kinase; PDBTitle: crystal structure of s. aureus pyruvate kinase in complex with a2 naturally occurring bis-indole alkaloid 45 c3odmE_ not modelled 97.6 19 PDB header:lyase Chain: E: PDB Molecule:phosphoenolpyruvate carboxylase; PDBTitle: archaeal-type phosphoenolpyruvate carboxylase 46 d1jqoa_ not modelled 76.0 10 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate carboxylase 47 c1jqoA_ not modelled 76.0 10 PDB header:lyase Chain: A: PDB Molecule:phosphoenolpyruvate carboxylase; PDBTitle: crystal structure of c4-form phosphoenolpyruvate carboxylase from2 maize 48 d1jqna_ not modelled 71.4 19 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate carboxylase 49 c3r3sD_ not modelled 62.3 17 PDB header:oxidoreductase Chain: D: PDB Molecule:oxidoreductase; PDBTitle: structure of the ygha oxidoreductase from salmonella enterica 50 c3i1jB_ not modelled 61.0 18 PDB header:oxidoreductase Chain: B: PDB Molecule:oxidoreductase, short chain PDBTitle: structure of a putative short chain dehydrogenase from2 pseudomonas syringae 51 c2x3mA_ not modelled 52.0 36 PDB header:unknown function Chain: A: PDB Molecule:hypothetical protein orf239; PDBTitle: crystal structure of hypothetical protein orf239 from pyrobaculum2 spherical virus 52 c3g5oC_ not modelled 40.9 13 PDB header:toxin/antitoxin Chain: C: PDB Molecule:uncharacterized protein rv2866; PDBTitle: the crystal structure of the toxin-antitoxin complex relbe2 (rv2865-2 2866) from mycobacterium tuberculosis 53 d1yxma1 not modelled 40.9 23 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 54 d1qasa3 not modelled 35.5 28 Fold:TIM beta/alpha-barrel Superfamily:PLC-like phosphodiesterases Family:Mammalian PLC 55 d1g0oa_ not modelled 30.2 22 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 56 d2zkmx4 not modelled 28.4 18 Fold:TIM beta/alpha-barrel Superfamily:PLC-like phosphodiesterases Family:Mammalian PLC 57 c3iv6C_ not modelled 26.6 29 PDB header:oxidoreductase Chain: C: PDB Molecule:putative zn-dependent alcohol dehydrogenase; PDBTitle: crystal structure of putative zn-dependent alcohol dehydrogenases from2 rhodobacter sphaeroides. 58 c2gjmA_ not modelled 26.1 16 PDB header:oxidoreductase Chain: A: PDB Molecule:lactoperoxidase; PDBTitle: crystal structure of buffalo lactoperoxidase at 2.75a resolution 59 c3qkbB_ not modelled 25.4 10 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a protein with unknown function which belongs to2 pfam duf74 family (pepe_0654) from pediococcus pentosaceus atcc 257453 at 2.73 a resolution 60 d1q45a_ not modelled 24.2 14 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 61 c3ohmB_ not modelled 22.4 18 PDB header:signaling protein / hydrolase Chain: B: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase PDBTitle: crystal structure of activated g alpha q bound to its effector2 phospholipase c beta 3 62 c1djyB_ not modelled 22.0 28 PDB header:lipid degradation Chain: B: PDB Molecule:phosphoinositide-specific phospholipase c, PDBTitle: phosphoinositide-specific phospholipase c-delta1 from rat2 complexed with inositol-2,4,5-trisphosphate 63 c3bbnD_ not modelled 22.0 27 PDB header:ribosome Chain: D: PDB Molecule:ribosomal protein s4; PDBTitle: homology model for the spinach chloroplast 30s subunit2 fitted to 9.4a cryo-em map of the 70s chlororibosome. 64 d1mn3a_ not modelled 20.6 23 Fold:RuvA C-terminal domain-like Superfamily:UBA-like Family:CUE domain 65 c1bknA_ not modelled 20.4 25 PDB header:dna repair Chain: A: PDB Molecule:mutl; PDBTitle: crystal structure of an n-terminal 40kd fragment of e. coli2 dna mismatch repair protein mutl 66 d1geea_ not modelled 19.9 30 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 67 d1gtea2 not modelled 19.8 11 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 68 c1ddxA_ not modelled 19.7 16 PDB header:oxidoreductase Chain: A: PDB Molecule:protein (prostaglandin h2 synthase-2); PDBTitle: crystal structure of a mixture of arachidonic acid and prostaglandin2 bound to the cyclooxygenase active site of cox-2: prostaglandin3 structure 69 c3pghD_ not modelled 19.4 19 PDB header:oxidoreductase Chain: D: PDB Molecule:cyclooxygenase-2; PDBTitle: cyclooxygenase-2 (prostaglandin synthase-2) complexed with a non-2 selective inhibitor, flurbiprofen 70 c2fjuB_ not modelled 18.9 18 PDB header:signaling protein,apoptosis/hydrolase Chain: B: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate PDBTitle: activated rac1 bound to its effector phospholipase c beta 2 71 c3gdbA_ not modelled 18.9 27 PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein spr0440; PDBTitle: crystal structure of spr0440 glycoside hydrolase domain,2 endo-d from streptococcus pneumoniae r6 72 d1cvua1 not modelled 18.3 19 Fold:Heme-dependent peroxidases Superfamily:Heme-dependent peroxidases Family:Myeloperoxidase-like 73 c3ivuB_ not modelled 18.3 12 PDB header:transferase Chain: B: PDB Molecule:homocitrate synthase, mitochondrial; PDBTitle: homocitrate synthase lys4 bound to 2-og 74 d1vyua2 not modelled 18.2 13 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 75 c1pggB_ not modelled 18.2 14 PDB header:oxidoreductase Chain: B: PDB Molecule:prostaglandin h2 synthase-1; PDBTitle: prostaglandin h2 synthase-1 complexed with 1-(4-iodobenzoyl)-5-2 methoxy-2-methylindole-3-acetic acid (iodoindomethacin), trans model 76 c1ht8B_ not modelled 18.2 14 PDB header:oxidoreductase Chain: B: PDB Molecule:prostaglandin h2 synthase-1; PDBTitle: the 2.7 angstrom resolution model of ovine cox-1 complexed with2 alclofenac 77 c3kvoB_ not modelled 18.1 20 PDB header:oxidoreductase Chain: B: PDB Molecule:hydroxysteroid dehydrogenase-like protein 2; PDBTitle: crystal structure of the catalytic domain of human hydroxysteroid2 dehydrogenase like 2 (hsdl2) 78 c1y2iC_ not modelled 17.2 11 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:hypothetical protein s0862; PDBTitle: crystal structure of mcsg target apc27401 from shigella2 flexneri 79 d1y2ia_ not modelled 17.2 11 Fold:Dodecin subunit-like Superfamily:YbjQ-like Family:YbjQ-like 80 c2w91A_ not modelled 16.8 26 PDB header:hydrolase Chain: A: PDB Molecule:endo-beta-n-acetylglucosaminidase d; PDBTitle: structure of a streptococcus pneumoniae family 85 glycoside2 hydrolase, endo-d. 81 c2oyuP_ not modelled 16.7 14 PDB header:oxidoreductase Chain: P: PDB Molecule:prostaglandin g/h synthase 1; PDBTitle: indomethacin-(s)-alpha-ethyl-ethanolamide bound to cyclooxygenase-1 82 c2qr6A_ not modelled 16.6 14 PDB header:oxidoreductase Chain: A: PDB Molecule:imp dehydrogenase/gmp reductase; PDBTitle: crystal structure of imp dehydrogenase/gmp reductase-like protein2 (np_599840.1) from corynebacterium glutamicum atcc 13032 kitasato at3 1.50 a resolution 83 c3qr0A_ not modelled 16.5 17 PDB header:hydrolase Chain: A: PDB Molecule:phospholipase c-beta (plc-beta); PDBTitle: crystal structure of s. officinalis plc21 84 c1zfjA_ not modelled 16.1 16 PDB header:oxidoreductase Chain: A: PDB Molecule:inosine monophosphate dehydrogenase; PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes 85 d1o70a2 not modelled 16.1 9 Fold:FAS1 domain Superfamily:FAS1 domain Family:FAS1 domain 86 c3mdoB_ not modelled 15.7 15 PDB header:ligase Chain: B: PDB Molecule:putative phosphoribosylformylglycinamidine cyclo-ligase; PDBTitle: crystal structure of a putative phosphoribosylformylglycinamidine2 cyclo-ligase (bdi_2101) from parabacteroides distasonis atcc 8503 at3 1.91 a resolution 87 c2a7rD_ not modelled 15.7 22 PDB header:oxidoreductase Chain: D: PDB Molecule:gmp reductase 2; PDBTitle: crystal structure of human guanosine monophosphate2 reductase 2 (gmpr2) 88 c3gafF_ not modelled 15.2 23 PDB header:oxidoreductase Chain: F: PDB Molecule:7-alpha-hydroxysteroid dehydrogenase; PDBTitle: 2.2a crystal structure of 7-alpha-hydroxysteroid2 dehydrogenase from brucella melitensis 89 d2cu0a1 not modelled 14.9 17 Fold:TIM beta/alpha-barrel Superfamily:Inosine monophosphate dehydrogenase (IMPDH) Family:Inosine monophosphate dehydrogenase (IMPDH) 90 c2kheA_ not modelled 14.9 12 PDB header:hydrolase Chain: A: PDB Molecule:toxin-like protein; PDBTitle: solution structure of the bacterial toxin rele from thermus2 thermophilus hb8 91 d1w6ua_ not modelled 14.8 20 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 92 d1uzma1 not modelled 14.6 21 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 93 d1q4ga1 not modelled 14.4 14 Fold:Heme-dependent peroxidases Superfamily:Heme-dependent peroxidases Family:Myeloperoxidase-like 94 d1pvna1 not modelled 14.2 17 Fold:TIM beta/alpha-barrel Superfamily:Inosine monophosphate dehydrogenase (IMPDH) Family:Inosine monophosphate dehydrogenase (IMPDH) 95 d2jn4a1 not modelled 14.1 21 Fold:NifT/FixU barrel-like Superfamily:NifT/FixU-like Family:NifT/FixU 96 c2jn4A_ not modelled 14.1 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein fixu, nift; PDBTitle: solution nmr structure of protein rp4601 from2 rhodopseudomonas palustris. northeast structural genomics3 consortium target rpt2; ontario center for structural4 proteomics target rp4601. 97 d1zfja1 not modelled 14.0 16 Fold:TIM beta/alpha-barrel Superfamily:Inosine monophosphate dehydrogenase (IMPDH) Family:Inosine monophosphate dehydrogenase (IMPDH) 98 c3rihB_ not modelled 14.0 28 PDB header:oxidoreductase Chain: B: PDB Molecule:short chain dehydrogenase or reductase; PDBTitle: crystal structure of a putative short chain dehydrogenase or reductase2 from mycobacterium abscessus 99 c1d2vD_ not modelled 14.0 19 PDB header:oxidoreductase Chain: D: PDB Molecule:myeloperoxidase; PDBTitle: crystal structure of bromide-bound human myeloperoxidase isoform c at2 ph 5.5