Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	H	V	T	A	K	P	S	S	F	Q	C	N	L	K	C	D	Y	C	F	Y	L	E	K	E	S	Q	F	T	H	E	K	W	M	D	D	S	T	L	K	E	F	I	K	Q	Y	I	A	A	S	G	N	Q	V	Y	F	T	W	Q	G
Secondary structure
SS confidence
Disorder		?					?	?																	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	E	P	T	L	A	G	L	D	F	F	R	K	V	I	H	Y	Q	Q	R	Y	A	G	Q	K	R	I	F	N	A	L	Q	T	N	G	I	L	L	N	N	E	W	C	A	F	L	K	E	H	E	F	L	V	G	I	S	I	D	G	P
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		Q	E	L	H	D	R	Y	R	R	S	N	S	G	N	G	T	F	A	K	V	I	A	A	I	E	R	L	K	S	Y	Q	V	E	F	N	T	L	T	V	I	N	N	V	N	V	H	Y	P	L	E	V	Y	H	F	L	K	S	I	G	S
Secondary structure
SS confidence
Disorder												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		K	H	M	Q	F	I	E	L	L	E	T	G	T	P	N	I	D	F	S	G	H	S	E	N	T	F	R	I	I	D	F	S	V	P	P	T	A	Y	G	K	F	M	S	T	I	F	M	Q	W	V	K	N	D	V	G	E	I	F	I	R
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		Q	F	E	S	F	V	S	R	F	L	G	N	G	H	T	S	C	I	F	Q	E	S	C	K	D	N	L	V	V	E	S	N	G	D	I	Y	E	C	D	H	F	V	Y	P	Q	Y	K	I	G	N	I	N	K	S	E	L	K	T	M	N
Secondary structure
SS confidence
Disorder															?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		S	V	Q	L	T	A	Q	K	K	R	I	P	A	K	C	Q	Q	C	A	Y	K	P	I	C	N	G	G	C	P	K	H	R	I	T	K	V	N	N	E	T	V	S	Y	F	C	E	G	Y	K	I	L	F	S	T	M	V	P	Y	M	N
Secondary structure
SS confidence
Disorder								?	?	?	?	?	?	?																						?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.
Sequence		A	M	V	E	L	A	K	N	R	V	P	L	Y	H	I	M	D	V	A	K	Q	M	E	N	N
Secondary structure
SS confidence
Disorder									?															?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1tv8 chain A Region: 2 - 314 Aligned: 292 Modelled: 312 Confidence: 100.0% Identity: 17% Fold: TIM beta/alpha-barrel Superfamily: Radical SAM enzymes Family: MoCo biosynthesis proteins Phyre2 PDB 2yx0 chain A Region: 3 - 190 Aligned: 180 Modelled: 188 Confidence: 99.9% Identity: 13% PDB header:metal binding protein Chain: A: PDB Molecule:radical sam enzyme; PDBTitle: crystal structure of p. horikoshii tyw1 Phyre2 PDB 3c8f chain A Region: 4 - 231 Aligned: 215 Modelled: 224 Confidence: 99.8% Identity: 15% PDB header:oxidoreductase Chain: A: PDB Molecule:pyruvate formate-lyase 1-activating enzyme; PDBTitle: 4fe-4s-pyruvate formate-lyase activating enzyme with2 partially disordered adomet Phyre2 PDB 2a5h chain C Region: 3 - 196 Aligned: 177 Modelled: 181 Confidence: 99.6% Identity: 15% PDB header:isomerase Chain: C: PDB Molecule:l-lysine 2,3-aminomutase; PDBTitle: 2.1 angstrom x-ray crystal structure of lysine-2,3-aminomutase from2 clostridium subterminale sb4, with michaelis analog (l-alpha-lysine3 external aldimine form of pyridoxal-5'-phosphate). Phyre2 PDB 1olt chain A Region: 3 - 242 Aligned: 229 Modelled: 232 Confidence: 99.6% Identity: 10% Fold: TIM beta/alpha-barrel Superfamily: Radical SAM enzymes Family: Oxygen-independent coproporphyrinogen III oxidase HemN Phyre2 PDB 1r30 chain A Region: 1 - 213 Aligned: 203 Modelled: 213 Confidence: 99.6% Identity: 11% PDB header:transferase Chain: A: PDB Molecule:biotin synthase; PDBTitle: the crystal structure of biotin synthase, an s-2 adenosylmethionine-dependent radical enzyme Phyre2 PDB 1r30 chain A Region: 1 - 213 Aligned: 203 Modelled: 213 Confidence: 99.6% Identity: 11% Fold: TIM beta/alpha-barrel Superfamily: Radical SAM enzymes Family: Biotin synthase Phyre2 PDB 3t7v chain A Region: 4 - 191 Aligned: 179 Modelled: 188 Confidence: 99.5% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:methylornithine synthase pylb; PDBTitle: crystal structure of methylornithine synthase (pylb) Phyre2 PDB 3cix chain A Region: 5 - 213 Aligned: 197 Modelled: 209 Confidence: 99.5% Identity: 12% PDB header:adomet binding protein Chain: A: PDB Molecule:fefe-hydrogenase maturase; PDBTitle: x-ray structure of the [fefe]-hydrogenase maturase hyde from2 thermotoga maritima in complex with thiocyanate Phyre2 PDB 2z2u chain A Region: 11 - 189 Aligned: 158 Modelled: 179 Confidence: 99.5% Identity: 20% PDB header:metal binding protein Chain: A: PDB Molecule:upf0026 protein mj0257; PDBTitle: crystal structure of archaeal tyw1 Phyre2 PDB 3can chain A Region: 56 - 194 Aligned: 129 Modelled: 136 Confidence: 99.5% Identity: 15% PDB header:lyase activator Chain: A: PDB Molecule:pyruvate-formate lyase-activating enzyme; PDBTitle: crystal structure of a domain of pyruvate-formate lyase-activating2 enzyme from bacteroides vulgatus atcc 8482 Phyre2 PDB 3rfa chain A Region: 12 - 200 Aligned: 183 Modelled: 189 Confidence: 99.4% Identity: 16% PDB header:oxidoreductase Chain: A: PDB Molecule:ribosomal rna large subunit methyltransferase n; PDBTitle: x-ray structure of rlmn from escherichia coli in complex with s-2 adenosylmethionine Phyre2 PDB 2qgq chain F Region: 16 - 190 Aligned: 169 Modelled: 175 Confidence: 98.9% Identity: 9% PDB header:structural genomics, unknown function Chain: F: PDB Molecule:protein tm_1862; PDBTitle: crystal structure of tm_1862 from thermotoga maritima.2 northeast structural genomics consortium target vr77 Phyre2 PDB 3ivu chain B Region: 24 - 185 Aligned: 149 Modelled: 158 Confidence: 97.2% Identity: 12% PDB header:transferase Chain: B: PDB Molecule:homocitrate synthase, mitochondrial; PDBTitle: homocitrate synthase lys4 bound to 2-og Phyre2 PDB 3ble chain A Region: 31 - 185 Aligned: 149 Modelled: 155 Confidence: 96.9% Identity: 11% PDB header:transferase Chain: A: PDB Molecule:citramalate synthase from leptospira interrogans; PDBTitle: crystal structure of the catalytic domain of licms in2 complexed with malonate Phyre2 PDB 3ewb chain X Region: 34 - 185 Aligned: 145 Modelled: 148 Confidence: 96.9% Identity: 11% PDB header:transferase Chain: X: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of n-terminal domain of putative 2-2 isopropylmalate synthase from listeria monocytogenes Phyre2 PDB 2ftp chain A Region: 31 - 185 Aligned: 148 Modelled: 149 Confidence: 96.8% Identity: 10% PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of hydroxymethylglutaryl-coa lyase from pseudomonas2 aeruginosa Phyre2 PDB 2cw6 chain B Region: 31 - 185 Aligned: 148 Modelled: 155 Confidence: 95.9% Identity: 11% PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria Phyre2 PDB 1ydo chain C Region: 31 - 185 Aligned: 148 Modelled: 151 Confidence: 95.8% Identity: 12% PDB header:lyase Chain: C: PDB Molecule:hmg-coa lyase; PDBTitle: crystal structure of the bacillis subtilis hmg-coa lyase, northeast2 structural genomics target sr181. Phyre2 PDB 1ydn chain A Region: 31 - 185 Aligned: 148 Modelled: 149 Confidence: 95.4% Identity: 7% PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of the hmg-coa lyase from brucella melitensis,2 northeast structural genomics target lr35. Phyre2 1 d1tv8a_ 2 c2yx0A_ 3 c3c8fA_ 4 c2a5hC_ 5 d1olta_ 6 c1r30A_ 7 d1r30a_ 8 c3t7vA_ 9 c3cixA_ 10 c2z2uA_ 11 c3canA_ 12 c3rfaA_ 13 c2qgqF_ 14 c3ivuB_ 15 c3bleA_ 16 c3ewbX_ 17 c2ftpA_ 18 c2cw6B_ 19 c1ydoC_ 20 c1ydnA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1tv8a_ 100.0 17 Fold:TIM beta/alpha-barrel Superfamily:Radical SAM enzymes Family:MoCo biosynthesis proteins 2 c2yx0A_ 99.9 13 PDB header:metal binding protein Chain: A: PDB Molecule:radical sam enzyme; PDBTitle: crystal structure of p. horikoshii tyw1 3 c3c8fA_ 99.8 15 PDB header:oxidoreductase Chain: A: PDB Molecule:pyruvate formate-lyase 1-activating enzyme; PDBTitle: 4fe-4s-pyruvate formate-lyase activating enzyme with2 partially disordered adomet 4 c2a5hC_ 99.6 15 PDB header:isomerase Chain: C: PDB Molecule:l-lysine 2,3-aminomutase; PDBTitle: 2.1 angstrom x-ray crystal structure of lysine-2,3-aminomutase from2 clostridium subterminale sb4, with michaelis analog (l-alpha-lysine3 external aldimine form of pyridoxal-5'-phosphate). 5 d1olta_ 99.6 10 Fold:TIM beta/alpha-barrel Superfamily:Radical SAM enzymes Family:Oxygen-independent coproporphyrinogen III oxidase HemN 6 c1r30A_ 99.6 11 PDB header:transferase Chain: A: PDB Molecule:biotin synthase; PDBTitle: the crystal structure of biotin synthase, an s-2 adenosylmethionine-dependent radical enzyme 7 d1r30a_ 99.6 11 Fold:TIM beta/alpha-barrel Superfamily:Radical SAM enzymes Family:Biotin synthase 8 c3t7vA_ 99.5 13 PDB header:transferase Chain: A: PDB Molecule:methylornithine synthase pylb; PDBTitle: crystal structure of methylornithine synthase (pylb) 9 c3cixA_ 99.5 12 PDB header:adomet binding protein Chain: A: PDB Molecule:fefe-hydrogenase maturase; PDBTitle: x-ray structure of the [fefe]-hydrogenase maturase hyde from2 thermotoga maritima in complex with thiocyanate 10 c2z2uA_ 99.5 20 PDB header:metal binding protein Chain: A: PDB Molecule:upf0026 protein mj0257; PDBTitle: crystal structure of archaeal tyw1 11 c3canA_ 99.5 15 PDB header:lyase activator Chain: A: PDB Molecule:pyruvate-formate lyase-activating enzyme; PDBTitle: crystal structure of a domain of pyruvate-formate lyase-activating2 enzyme from bacteroides vulgatus atcc 8482 12 c3rfaA_ 99.4 16 PDB header:oxidoreductase Chain: A: PDB Molecule:ribosomal rna large subunit methyltransferase n; PDBTitle: x-ray structure of rlmn from escherichia coli in complex with s-2 adenosylmethionine 13 c2qgqF_ 98.9 9 PDB header:structural genomics, unknown function Chain: F: PDB Molecule:protein tm_1862; PDBTitle: crystal structure of tm_1862 from thermotoga maritima.2 northeast structural genomics consortium target vr77 14 c3ivuB_ 97.2 12 PDB header:transferase Chain: B: PDB Molecule:homocitrate synthase, mitochondrial; PDBTitle: homocitrate synthase lys4 bound to 2-og 15 c3bleA_ 96.9 11 PDB header:transferase Chain: A: PDB Molecule:citramalate synthase from leptospira interrogans; PDBTitle: crystal structure of the catalytic domain of licms in2 complexed with malonate 16 c3ewbX_ 96.9 11 PDB header:transferase Chain: X: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of n-terminal domain of putative 2-2 isopropylmalate synthase from listeria monocytogenes 17 c2ftpA_ 96.8 10 PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of hydroxymethylglutaryl-coa lyase from pseudomonas2 aeruginosa 18 c2cw6B_ 95.9 11 PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria 19 c1ydoC_ 95.8 12 PDB header:lyase Chain: C: PDB Molecule:hmg-coa lyase; PDBTitle: crystal structure of the bacillis subtilis hmg-coa lyase, northeast2 structural genomics target sr181. 20 c1ydnA_ 95.4 7 PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of the hmg-coa lyase from brucella melitensis,2 northeast structural genomics target lr35. 21 c3eegB_ not modelled 93.7 8 PDB header:transferase Chain: B: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of a 2-isopropylmalate synthase from2 cytophaga hutchinsonii 22 c1nvmG_ not modelled 85.9 8 PDB header:lyase/oxidoreductase Chain: G: PDB Molecule:4-hydroxy-2-oxovalerate aldolase; PDBTitle: crystal structure of a bifunctional aldolase-dehydrogenase :2 sequestering a reactive and volatile intermediate 23 c1sr9A_ not modelled 84.6 9 PDB header:transferase Chain: A: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of leua from mycobacterium tuberculosis 24 c2qv5A_ not modelled 72.7 9 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein atu2773; PDBTitle: crystal structure of uncharacterized protein atu2773 from2 agrobacterium tumefaciens c58 25 d1nvma2 not modelled 70.9 9 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:HMGL-like 26 c1rr2A_ not modelled 70.7 14 PDB header:transferase Chain: A: PDB Molecule:transcarboxylase 5s subunit; PDBTitle: propionibacterium shermanii transcarboxylase 5s subunit bound to 2-2 ketobutyric acid 27 c2zyfA_ not modelled 69.1 11 PDB header:transferase Chain: A: PDB Molecule:homocitrate synthase; PDBTitle: crystal structure of homocitrate synthase from thermus thermophilus2 complexed with magnesuim ion and alpha-ketoglutarate 28 c3dxiB_ not modelled 65.9 9 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative aldolase; PDBTitle: crystal structure of the n-terminal domain of a putative2 aldolase (bvu_2661) from bacteroides vulgatus 29 c2vefB_ not modelled 59.6 9 PDB header:transferase Chain: B: PDB Molecule:dihydropteroate synthase; PDBTitle: dihydropteroate synthase from streptococcus pneumoniae 30 c2nx9B_ not modelled 57.2 12 PDB header:lyase Chain: B: PDB Molecule:oxaloacetate decarboxylase 2, subunit alpha; PDBTitle: crystal structure of the carboxyltransferase domain of the2 oxaloacetate decarboxylase na+ pump from vibrio cholerae 31 d2nlya1 not modelled 55.1 9 Fold:7-stranded beta/alpha barrel Superfamily:Glycoside hydrolase/deacetylase Family:Divergent polysaccharide deacetylase 32 c3iwpK_ not modelled 54.9 11 PDB header:metal binding protein Chain: K: PDB Molecule:copper homeostasis protein cutc homolog; PDBTitle: crystal structure of human copper homeostasis protein cutc 33 c2zq0B_ not modelled 54.3 11 PDB header:hydrolase Chain: B: PDB Molecule:alpha-glucosidase (alpha-glucosidase susb); PDBTitle: crystal structure of susb complexed with acarbose 34 c2bdqA_ not modelled 54.2 11 PDB header:metal transport Chain: A: PDB Molecule:copper homeostasis protein cutc; PDBTitle: crystal structure of the putative copper homeostasis2 protein cutc from streptococcus agalactiae, northeast3 strucural genomics target sar15. 35 d1muwa_ not modelled 53.7 8 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 36 c3hpxB_ not modelled 52.5 9 PDB header:transferase Chain: B: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of mycobacterium tuberculosis leua active site2 domain 1-425 (truncation mutant delta:426-644) 37 d1ajza_ not modelled 51.5 13 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 38 c3czkA_ not modelled 50.3 8 PDB header:hydrolase Chain: A: PDB Molecule:sucrose hydrolase; PDBTitle: crystal structure analysis of sucrose hydrolase(suh) e322q-2 sucrose complex 39 d1tx2a_ not modelled 50.1 15 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 40 c1tx2A_ not modelled 50.1 15 PDB header:transferase Chain: A: PDB Molecule:dhps, dihydropteroate synthase; PDBTitle: dihydropteroate synthetase, with bound inhibitor manic, from bacillus2 anthracis 41 d1g5aa2 not modelled 49.8 8 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 42 c3bg3B_ not modelled 47.8 14 PDB header:ligase Chain: B: PDB Molecule:pyruvate carboxylase, mitochondrial; PDBTitle: crystal structure of human pyruvate carboxylase (missing2 the biotin carboxylase domain at the n-terminus) 43 d2zdra2 not modelled 47.6 15 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:NeuB-like 44 c1jgiA_ not modelled 47.5 8 PDB header:transferase Chain: A: PDB Molecule:amylosucrase; PDBTitle: crystal structure of the active site mutant glu328gln of2 amylosucrase from neisseria polysaccharea in complex with3 the natural substrate sucrose 45 c3n2xB_ not modelled 46.8 13 PDB header:lyase Chain: B: PDB Molecule:uncharacterized protein yage; PDBTitle: crystal structure of yage, a prophage protein belonging to the2 dihydrodipicolinic acid synthase family from e. coli k12 in complex3 with pyruvate 46 c3ol0C_ not modelled 45.0 14 PDB header:de novo protein Chain: C: PDB Molecule:de novo designed monomer trefoil-fold sub-domain which PDBTitle: crystal structure of monofoil-4p homo-trimer: de novo designed monomer2 trefoil-fold sub-domain which forms homo-trimer assembly 47 c2knpA_ not modelled 44.9 43 PDB header:unknown function Chain: A: PDB Molecule:mcocc-1; PDBTitle: isolation and characterization of peptides from momordica2 cochinchinensis seeds. 48 d1twda_ not modelled 44.3 10 Fold:TIM beta/alpha-barrel Superfamily:CutC-like Family:CutC-like 49 d1yhta1 not modelled 40.9 15 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-N-acetylhexosaminidase catalytic domain 50 c3dz1A_ not modelled 39.1 11 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 rhodopseudomonas palustris at 1.87a resolution 51 c3chvA_ not modelled 36.8 13 PDB header:metal binding protein Chain: A: PDB Molecule:prokaryotic domain of unknown function (duf849) with a tim PDBTitle: crystal structure of a prokaryotic domain of unknown function (duf849)2 member (spoa0042) from silicibacter pomeroyi dss-3 at 1.45 a3 resolution 52 c2gjxE_ not modelled 35.3 9 PDB header:hydrolase Chain: E: PDB Molecule:beta-hexosaminidase alpha chain; PDBTitle: crystallographic structure of human beta-hexosaminidase a 53 c2ekcA_ not modelled 33.8 11 PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5 54 c3hf3A_ not modelled 33.7 20 PDB header:oxidoreductase Chain: A: PDB Molecule:chromate reductase; PDBTitle: old yellow enzyme from thermus scotoductus sa-01 55 c3lciA_ not modelled 31.1 15 PDB header:lyase Chain: A: PDB Molecule:n-acetylneuraminate lyase; PDBTitle: the d-sialic acid aldolase mutant v251w 56 d1qwga_ not modelled 30.5 14 Fold:TIM beta/alpha-barrel Superfamily:(2r)-phospho-3-sulfolactate synthase ComA Family:(2r)-phospho-3-sulfolactate synthase ComA 57 c3cprB_ not modelled 29.9 11 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthetase; PDBTitle: the crystal structure of corynebacterium glutamicum2 dihydrodipicolinate synthase to 2.2 a resolution 58 d1qt1a_ not modelled 29.8 9 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 59 c2v9dB_ not modelled 26.9 13 PDB header:lyase Chain: B: PDB Molecule:yage; PDBTitle: crystal structure of yage, a prophage protein belonging to2 the dihydrodipicolinic acid synthase family from e. coli3 k12 60 c3navB_ not modelled 26.5 11 PDB header:lyase Chain: B: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: crystal structure of an alpha subunit of tryptophan synthase from2 vibrio cholerae o1 biovar el tor str. n16961 61 d2a6na1 not modelled 26.2 11 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 62 d1v93a_ not modelled 25.5 15 Fold:TIM beta/alpha-barrel Superfamily:FAD-linked oxidoreductase Family:Methylenetetrahydrofolate reductase 63 c1ps9A_ not modelled 25.3 12 PDB header:oxidoreductase Chain: A: PDB Molecule:2,4-dienoyl-coa reductase; PDBTitle: the crystal structure and reaction mechanism of e. coli 2,4-2 dienoyl coa reductase 64 c3rpmA_ not modelled 25.2 14 PDB header:hydrolase Chain: A: PDB Molecule:beta-n-acetyl-hexosaminidase; PDBTitle: crystal structure of the first gh20 domain of a novel beta-n-acetyl-2 hexosaminidase strh from streptococcus pneumoniae r6 65 c3e02A_ not modelled 25.2 11 PDB header:metal binding protein Chain: A: PDB Molecule:uncharacterized protein duf849; PDBTitle: crystal structure of a duf849 family protein (bxe_c0271) from2 burkholderia xenovorans lb400 at 1.90 a resolution 66 d1hl2a_ not modelled 25.1 15 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 67 d1ad1a_ not modelled 25.1 9 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 68 c1nouA_ not modelled 25.0 12 PDB header:hydrolase Chain: A: PDB Molecule:beta-hexosaminidase beta chain; PDBTitle: native human lysosomal beta-hexosaminidase isoform b 69 d1m53a2 not modelled 24.3 10 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 70 c1qysA_ not modelled 24.2 13 PDB header:de novo protein Chain: A: PDB Molecule:top7; PDBTitle: crystal structure of top7: a computationally designed2 protein with a novel fold 71 c2ylaA_ not modelled 24.1 12 PDB header:hydrolase Chain: A: PDB Molecule:beta-n-acetylhexosaminidase; PDBTitle: inhibition of the pneumococcal virulence factor strh and2 molecular insights into n-glycan recognition and3 hydrolysis 72 c2g7zB_ not modelled 23.8 5 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:conserved hypothetical protein spy1493; PDBTitle: conserved degv-like protein of unknown function from streptococcus2 pyogenes m1 gas binds long-chain fatty acids 73 c3khdC_ not modelled 23.6 7 PDB header:transferase Chain: C: PDB Molecule:pyruvate kinase; PDBTitle: crystal structure of pff1300w. 74 d1nowa1 not modelled 22.1 13 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-N-acetylhexosaminidase catalytic domain 75 d1z41a1 not modelled 22.1 11 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 76 c2ou4C_ not modelled 21.1 9 PDB header:isomerase Chain: C: PDB Molecule:d-tagatose 3-epimerase; PDBTitle: crystal structure of d-tagatose 3-epimerase from2 pseudomonas cichorii 77 c3b4uB_ not modelled 20.6 11 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from agrobacterium2 tumefaciens str. c58 78 c2qmaB_ not modelled 20.4 18 PDB header:transferase Chain: B: PDB Molecule:diaminobutyrate-pyruvate transaminase and l-2,4- PDBTitle: crystal structure of glutamate decarboxylase domain of2 diaminobutyrate-pyruvate transaminase and l-2,4-diaminobutyrate3 decarboxylase from vibrio parahaemolyticus 79 c3g0sA_ not modelled 20.1 13 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: dihydrodipicolinate synthase from salmonella typhimurium lt2 80 c3fluD_ not modelled 20.0 10 PDB header:lyase Chain: D: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from the pathogen2 neisseria meningitidis 81 d1uwva2 not modelled 19.9 45 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:(Uracil-5-)-methyltransferase 82 d1eyea_ not modelled 19.8 17 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 83 c3pueA_ not modelled 19.7 15 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of the complex of dhydrodipicolinate synthase from2 acinetobacter baumannii with lysine at 2.6a resolution 84 c2jvfA_ not modelled 19.6 17 PDB header:de novo protein Chain: A: PDB Molecule:de novo protein m7; PDBTitle: solution structure of m7, a computationally-designed2 artificial protein 85 c3qfeB_ not modelled 19.6 8 PDB header:lyase Chain: B: PDB Molecule:putative dihydrodipicolinate synthase family protein; PDBTitle: crystal structures of a putative dihydrodipicolinate synthase family2 protein from coccidioides immitis 86 c3lmyA_ not modelled 19.3 8 PDB header:hydrolase Chain: A: PDB Molecule:beta-hexosaminidase subunit beta; PDBTitle: the crystal structure of beta-hexosaminidase b in complex with2 pyrimethamine 87 c1xuzA_ not modelled 19.0 16 PDB header:biosynthetic protein Chain: A: PDB Molecule:polysialic acid capsule biosynthesis protein siac; PDBTitle: crystal structure analysis of sialic acid synthase (neub)from2 neisseria meningitidis, bound to mn2+, phosphoenolpyruvate, and n-3 acetyl mannosaminitol 88 c2dh3A_ not modelled 18.6 21 PDB header:transport protein, signaling protein Chain: A: PDB Molecule:4f2 cell-surface antigen heavy chain; PDBTitle: crystal structure of human ed-4f2hc 89 c3ogfA_ not modelled 18.3 10 PDB header:de novo protein Chain: A: PDB Molecule:de novo designed dimeric trefoil-fold sub-domain which PDBTitle: crystal structure of difoil-4p homo-trimer: de novo designed dimeric2 trefoil-fold sub-domain which forms homo-trimer assembly 90 c3ct7E_ not modelled 17.5 11 PDB header:isomerase Chain: E: PDB Molecule:d-allulose-6-phosphate 3-epimerase; PDBTitle: crystal structure of d-allulose 6-phosphate 3-epimerase2 from escherichia coli k-12 91 c3lppA_ not modelled 16.7 14 PDB header:hydrolase Chain: A: PDB Molecule:sucrase-isomaltase; PDBTitle: crystal complex of n-terminal sucrase-isomaltase with kotalanol 92 c3rcnA_ not modelled 16.7 13 PDB header:hydrolase Chain: A: PDB Molecule:beta-n-acetylhexosaminidase; PDBTitle: crystal structure of beta-n-acetylhexosaminidase from arthrobacter2 aurescens 93 c3no5C_ not modelled 16.4 15 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a pfam duf849 domain containing protein2 (reut_a1631) from ralstonia eutropha jmp134 at 1.90 a resolution 94 c1uwvA_ not modelled 16.0 50 PDB header:transferase Chain: A: PDB Molecule:23s rrna (uracil-5-)-methyltransferase ruma; PDBTitle: crystal structure of ruma, the iron-sulfur cluster2 containing e. coli 23s ribosomal rna 5-methyluridine3 methyltransferase 95 d1qbaa3 not modelled 15.6 23 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-N-acetylhexosaminidase catalytic domain 96 c2ehhE_ not modelled 15.6 16 PDB header:lyase Chain: E: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 aquifex aeolicus 97 d1o5ka_ not modelled 15.5 10 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 98 c3daqB_ not modelled 15.4 9 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from methicillin-2 resistant staphylococcus aureus 99 c2rfgB_ not modelled 15.3 9 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from hahella2 chejuensis at 1.5a resolution

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0