Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP75822
DateThu Jan 5 12:14:36 GMT 2012
Unique Job ID004a59208d497d60

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1z45A_
Top template information
PDB header:isomerase
Chain: A: PDB Molecule:gal10 bifunctional protein;
PDBTitle: crystal structure of the gal10 fusion protein galactose2 mutarotase/udp-galactose 4-epimerase from saccharomyces3 cerevisiae complexed with nad, udp-glucose, and galactose
Confidence and coverage
Confidence:100.0% Coverage: 56%
268 residues ( 56% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
368 residues ( 77%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MPQRILVLGASGYIGQHLVRTLSQQGHQILAAARHVDRLAKLQLANVSCHKVDLSWPDNL
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   .........70.........80.........90.........100.........110.........120
Sequence  PALLQDIDTVYFLVHSMGEGGDFIAQERQVALNVRDALREVPVKQLIFLSSLQAPPHEQS
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   .........130.........140.........150.........160.........170.........180
Sequence  DHLRARQATADILREANVPVTELRAGIIVGAGSAAFEVMRDMVYNLPVLTPPRWVRSRTT
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   .........190.........200.........210.........220.........230.........240
Sequence  PIALENLLHYLVALLDHPASEHRIFEAAGPEVLSYQQQFEHFMAVSGKRRWLIPIPLPTR
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   .........250.........260.........270.........280.........290.........300
Sequence  WISVWFLNVITSVPPTTARALIQGLKHDLLADDTALRALIPQRLIAFDDAVRSTLKEEEK
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   .........310.........320.........330.........340.........350.........360
Sequence  LVNSSDWGYDAQAFARWRPEYGYFAKQAGFTVKTSASLAALWQVVNQIGGKERYFFGNIL
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Disorder 

??????????????
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   .........370.........380.........390.........400.........410.........420
Sequence  WQTRALMDRAIGHKLAKGRPEREYLQTGDAVDSWKVIVVEPEKQLTLLFGMKAPGLGRLC
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?????????

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   .........430.........440.........450.........460.........470......
Sequence  FSLEDKGDYRTIDVRAFWHPHGMPGLFYWLLMIPAHLFIFRGMAKQIARLAEQSTD
Secondary structure 








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????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1z45 chain A

3D model

Region: 2 - 302
Aligned: 268
Modelled: 268
Confidence: 100.0%
Identity: 23%
PDB header:isomerase
Chain: A: PDB Molecule:gal10 bifunctional protein;
PDBTitle: crystal structure of the gal10 fusion protein galactose2 mutarotase/udp-galactose 4-epimerase from saccharomyces3 cerevisiae complexed with nad, udp-glucose, and galactose

Phyre2

PDB 1z7e chain C

3D model

Region: 3 - 305
Aligned: 293
Modelled: 303
Confidence: 100.0%
Identity: 16%
PDB header:hydrolase
Chain: C: PDB Molecule:protein arna;
PDBTitle: crystal structure of full length arna

Phyre2

PDB 1i24 chain A

3D model

Region: 3 - 301
Aligned: 279
Modelled: 280
Confidence: 100.0%
Identity: 18%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 3oh8 chain A

3D model

Region: 2 - 300
Aligned: 283
Modelled: 299
Confidence: 100.0%
Identity: 11%
PDB header:isomerase
Chain: A: PDB Molecule:nucleoside-diphosphate sugar epimerase (sula family);
PDBTitle: crystal structure of the nucleoside-diphosphate sugar epimerase from2 corynebacterium glutamicum. northeast structural genomics consortium3 target cgr91

Phyre2

PDB 3e48 chain B

3D model

Region: 3 - 301
Aligned: 286
Modelled: 298
Confidence: 100.0%
Identity: 13%
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative nucleoside-diphosphate-sugar epimerase;
PDBTitle: crystal structure of a nucleoside-diphosphate-sugar epimerase2 (sav0421) from staphylococcus aureus, northeast structural genomics3 consortium target zr319

Phyre2

PDB 2qx7 chain A

3D model

Region: 1 - 305
Aligned: 293
Modelled: 296
Confidence: 100.0%
Identity: 15%
PDB header:plant protein
Chain: A: PDB Molecule:eugenol synthase 1;
PDBTitle: structure of eugenol synthase from ocimum basilicum

Phyre2

PDB 2v6g chain A

3D model

Region: 2 - 305
Aligned: 303
Modelled: 304
Confidence: 100.0%
Identity: 14%
PDB header:oxidoreductase
Chain: A: PDB Molecule:progesterone 5-beta-reductase;
PDBTitle: structure of progesterone 5beta-reductase from digitalis2 lanata in complex with nadp

Phyre2

PDB 2vrc chain D

3D model

Region: 1 - 295
Aligned: 283
Modelled: 293
Confidence: 100.0%
Identity: 18%
PDB header:oxidoreductase
Chain: D: PDB Molecule:triphenylmethane reductase;
PDBTitle: crystal structure of the citrobacter sp. triphenylmethane2 reductase complexed with nadp(h)

Phyre2

PDB 3c1o chain A

3D model

Region: 1 - 297
Aligned: 287
Modelled: 288
Confidence: 100.0%
Identity: 14%
PDB header:oxidoreductase
Chain: A: PDB Molecule:eugenol synthase;
PDBTitle: the multiple phenylpropene synthases in both clarkia2 breweri and petunia hybrida represent two distinct lineages

Phyre2

PDB 1xgk chain A

3D model

Region: 3 - 307
Aligned: 299
Modelled: 305
Confidence: 100.0%
Identity: 18%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 2zcu chain A

3D model

Region: 5 - 293
Aligned: 269
Modelled: 275
Confidence: 100.0%
Identity: 18%
PDB header:oxidoreductase
Chain: A: PDB Molecule:uncharacterized oxidoreductase ytfg;
PDBTitle: crystal structure of a new type of nadph-dependent quinone2 oxidoreductase (qor2) from escherichia coli

Phyre2

PDB 2c5a chain A domain 1

3D model

Region: 3 - 322
Aligned: 293
Modelled: 295
Confidence: 100.0%
Identity: 19%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1qyd chain A

3D model

Region: 3 - 293
Aligned: 286
Modelled: 291
Confidence: 100.0%
Identity: 15%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 2b69 chain A domain 1

3D model

Region: 3 - 301
Aligned: 273
Modelled: 275
Confidence: 100.0%
Identity: 15%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 2b69 chain A

3D model

Region: 3 - 301
Aligned: 273
Modelled: 275
Confidence: 100.0%
Identity: 15%
PDB header:lyase
Chain: A: PDB Molecule:udp-glucuronate decarboxylase 1;
PDBTitle: crystal structure of human udp-glucoronic acid decarboxylase

Phyre2

PDB 1db3 chain A

3D model

Region: 2 - 300
Aligned: 287
Modelled: 299
Confidence: 100.0%
Identity: 16%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1e6u chain A

3D model

Region: 3 - 301
Aligned: 261
Modelled: 261
Confidence: 100.0%
Identity: 18%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1qyc chain A

3D model

Region: 3 - 293
Aligned: 282
Modelled: 282
Confidence: 100.0%
Identity: 15%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 2gn9 chain B

3D model

Region: 1 - 229
Aligned: 226
Modelled: 229
Confidence: 100.0%
Identity: 17%
PDB header:lyase
Chain: B: PDB Molecule:udp-glcnac c6 dehydratase;
PDBTitle: crystal structure of udp-glcnac inverting 4,6-dehydratase in complex2 with nadp and udp-glc

Phyre2

PDB 1oc2 chain A

3D model

Region: 1 - 301
Aligned: 276
Modelled: 278
Confidence: 100.0%
Identity: 13%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 2uv9 chain B

3D model

Region: 3 - 368
Aligned: 355
Modelled: 355
Confidence: 99.9%
Identity: 15%
PDB header:transferase
Chain: B: PDB Molecule:fatty acid synthase alpha subunits;
PDBTitle: crystal structure of fatty acid synthase from thermomyces2 lanuginosus at 3.1 angstrom resolution. this file contains3 the alpha subunits of the fatty acid synthase. the entire4 crystal structure consists of one heterododecameric fatty5 acid synthase and is described in remark 400

Phyre2
1

c1z45A_
2

c1z7eC_
3

d1i24a_
4

c3oh8A_
5

c3e48B_
6

c2qx7A_
7

c2v6gA_
8

c2vrcD_
9

c3c1oA_
10

d1xgka_
11

c2zcuA_
12

d2c5aa1
13

d1qyda_
14

d2b69a1
15

c2b69A_
16

d1db3a_
17

d1e6ua_
18

d1qyca_
19

c2gn9B_
20

d1oc2a_
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c2uv9B_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1z45A_



100.0 23 PDB header:isomerase
Chain: A: PDB Molecule:gal10 bifunctional protein;
PDBTitle: crystal structure of the gal10 fusion protein galactose2 mutarotase/udp-galactose 4-epimerase from saccharomyces3 cerevisiae complexed with nad, udp-glucose, and galactose
2c1z7eC_



100.0 16 PDB header:hydrolase
Chain: C: PDB Molecule:protein arna;
PDBTitle: crystal structure of full length arna
3d1i24a_



100.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
4c3oh8A_



100.0 11 PDB header:isomerase
Chain: A: PDB Molecule:nucleoside-diphosphate sugar epimerase (sula family);
PDBTitle: crystal structure of the nucleoside-diphosphate sugar epimerase from2 corynebacterium glutamicum. northeast structural genomics consortium3 target cgr91
5c3e48B_



100.0 13 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative nucleoside-diphosphate-sugar epimerase;
PDBTitle: crystal structure of a nucleoside-diphosphate-sugar epimerase2 (sav0421) from staphylococcus aureus, northeast structural genomics3 consortium target zr319
6c2qx7A_



100.0 15 PDB header:plant protein
Chain: A: PDB Molecule:eugenol synthase 1;
PDBTitle: structure of eugenol synthase from ocimum basilicum
7c2v6gA_



100.0 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:progesterone 5-beta-reductase;
PDBTitle: structure of progesterone 5beta-reductase from digitalis2 lanata in complex with nadp
8c2vrcD_



100.0 18 PDB header:oxidoreductase
Chain: D: PDB Molecule:triphenylmethane reductase;
PDBTitle: crystal structure of the citrobacter sp. triphenylmethane2 reductase complexed with nadp(h)
9c3c1oA_



100.0 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:eugenol synthase;
PDBTitle: the multiple phenylpropene synthases in both clarkia2 breweri and petunia hybrida represent two distinct lineages
10d1xgka_



100.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
11c2zcuA_



100.0 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:uncharacterized oxidoreductase ytfg;
PDBTitle: crystal structure of a new type of nadph-dependent quinone2 oxidoreductase (qor2) from escherichia coli
12d2c5aa1



100.0 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
13d1qyda_



100.0 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
14d2b69a1



100.0 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
15c2b69A_



100.0 15 PDB header:lyase
Chain: A: PDB Molecule:udp-glucuronate decarboxylase 1;
PDBTitle: crystal structure of human udp-glucoronic acid decarboxylase
16d1db3a_



100.0 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
17d1e6ua_



100.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
18d1qyca_



100.0 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
19c2gn9B_



100.0 17 PDB header:lyase
Chain: B: PDB Molecule:udp-glcnac c6 dehydratase;
PDBTitle: crystal structure of udp-glcnac inverting 4,6-dehydratase in complex2 with nadp and udp-glc
20d1oc2a_



100.0 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
21c2x4gA_



not modelled 100.0 18 PDB header:isomerase
Chain: A: PDB Molecule:nucleoside-diphosphate-sugar epimerase;
PDBTitle: crystal structure of pa4631, a nucleoside-diphosphate-sugar2 epimerase from pseudomonas aeruginosa
22c2z1mC_



not modelled 100.0 14 PDB header:lyase
Chain: C: PDB Molecule:gdp-d-mannose dehydratase;
PDBTitle: crystal structure of gdp-d-mannose dehydratase from aquifex aeolicus2 vf5
23c3i5mA_



not modelled 100.0 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative leucoanthocyanidin reductase 1;
PDBTitle: structure of the apo form of leucoanthocyanidin reductase from vitis2 vinifera
24d1vl0a_



not modelled 100.0 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
25c2gasA_



not modelled 100.0 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:isoflavone reductase;
PDBTitle: crystal structure of isoflavone reductase
26c2c20D_



not modelled 100.0 15 PDB header:isomerase
Chain: D: PDB Molecule:udp-glucose 4-epimerase;
PDBTitle: crystal structure of udp-glucose 4-epimerase
27c3m2pD_



not modelled 100.0 16 PDB header:isomerase
Chain: D: PDB Molecule:udp-n-acetylglucosamine 4-epimerase;
PDBTitle: the crystal structure of udp-n-acetylglucosamine 4-epimerase2 from bacillus cereus
28c3sc6F_



not modelled 100.0 15 PDB header:oxidoreductase
Chain: F: PDB Molecule:dtdp-4-dehydrorhamnose reductase;
PDBTitle: 2.65 angstrom resolution crystal structure of dtdp-4-dehydrorhamnose2 reductase (rfbd) from bacillus anthracis str. ames in complex with3 nadp
29c2exxB_



not modelled 100.0 13 PDB header:unknown function
Chain: B: PDB Molecule:hscarg protein;
PDBTitle: crystal structure of hscarg from homo sapiens in complex with nadp
30d1ek6a_



not modelled 100.0 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
31c2iodD_



not modelled 100.0 14 PDB header:oxidoreductase
Chain: D: PDB Molecule:dihydroflavonol 4-reductase;
PDBTitle: binding of two substrate analogue molecules to2 dihydroflavonol-4-reductase alters the functional geometry3 of the catalytic site
32d1n2sa_



not modelled 100.0 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
33c3enkB_



not modelled 100.0 19 PDB header:isomerase
Chain: B: PDB Molecule:udp-glucose 4-epimerase;
PDBTitle: 1.9a crystal structure of udp-glucose 4-epimerase from2 burkholderia pseudomallei
34c2yy7B_



not modelled 100.0 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:l-threonine dehydrogenase;
PDBTitle: crystal structure of thermolabile l-threonine dehydrogenase from2 flavobacterium frigidimaris kuc-1
35c2p5uC_



not modelled 100.0 18 PDB header:isomerase
Chain: C: PDB Molecule:udp-glucose 4-epimerase;
PDBTitle: crystal structure of thermus thermophilus hb8 udp-glucose 4-2 epimerase complex with nad
36d1wvga1



not modelled 100.0 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
37c2hrzA_



not modelled 100.0 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:nucleoside-diphosphate-sugar epimerase;
PDBTitle: the crystal structure of the nucleoside-diphosphate-sugar epimerase2 from agrobacterium tumefaciens
38c2pzlB_



not modelled 100.0 18 PDB header:sugar binding protein
Chain: B: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase;
PDBTitle: crystal structure of the bordetella bronchiseptica enzyme2 wbmg in complex with nad and udp
39d1z45a2



not modelled 100.0 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
40d1y1pa1



not modelled 100.0 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
41c1n7gB_



not modelled 100.0 13 PDB header:lyase
Chain: B: PDB Molecule:gdp-d-mannose-4,6-dehydratase;
PDBTitle: crystal structure of the gdp-mannose 4,6-dehydratase2 ternary complex with nadph and gdp-rhamnose.
42c2q1wC_



not modelled 100.0 14 PDB header:sugar binding protein
Chain: C: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase;
PDBTitle: crystal structure of the bordetella bronchiseptica enzyme wbmh in2 complex with nad+
43d1t2aa_



not modelled 100.0 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
44d1rkxa_



not modelled 100.0 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
45c1t2aC_



not modelled 100.0 15 PDB header:structural genomics,lyase
Chain: C: PDB Molecule:gdp-mannose 4,6 dehydratase;
PDBTitle: crystal structure of human gdp-d-mannose 4,6-dehydratase
46c2q1uA_



not modelled 100.0 16 PDB header:sugar binding protein
Chain: A: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase;
PDBTitle: crystal structure of the bordetella bronchiseptica enzyme wbmf in2 complex with nad+ and udp
47c2pk3B_



not modelled 100.0 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:gdp-6-deoxy-d-lyxo-4-hexulose reductase;
PDBTitle: crystal structure of a gdp-4-keto-6-deoxy-d-mannose reductase
48c3eheB_



not modelled 100.0 16 PDB header:isomerase
Chain: B: PDB Molecule:udp-glucose 4-epimerase (gale-1);
PDBTitle: crystal structure of udp-glucose 4 epimerase (gale-1) from2 archaeoglobus fulgidus
49c2zklA_



not modelled 100.0 15 PDB header:isomerase
Chain: A: PDB Molecule:capsular polysaccharide synthesis enzyme cap5f;
PDBTitle: crystal structure of capsular polysaccharide assembling protein capf2 from staphylococcus aureus
50c2hunB_



not modelled 100.0 15 PDB header:lyase
Chain: B: PDB Molecule:336aa long hypothetical dtdp-glucose 4,6-dehydratase;
PDBTitle: crystal structure of hypothetical protein ph0414 from pyrococcus2 horikoshii ot3
51d1r6da_



not modelled 100.0 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
52c2p4hX_



not modelled 100.0 14 PDB header:plant protein
Chain: X: PDB Molecule:vestitone reductase;
PDBTitle: crystal structure of vestitone reductase from alfalfa2 (medicago sativa l.)
53c3iusB_



not modelled 100.0 16 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized conserved protein;
PDBTitle: the structure of a functionally unknown conserved protein2 from silicibacter pomeroyi dss
54d1orra_



not modelled 100.0 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
55d1kewa_



not modelled 100.0 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
56d1n7ha_



not modelled 100.0 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
57c2ydyA_



not modelled 100.0 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:methionine adenosyltransferase 2 subunit beta;
PDBTitle: crystal structure of human s-adenosylmethionine synthetase2 2, beta subunit in orthorhombic crystal form
58c3lu1C_



not modelled 100.0 14 PDB header:isomerase
Chain: C: PDB Molecule:wbgu;
PDBTitle: crystal structure analysis of wbgu: a udp-galnac 4-epimerase
59d1bxka_



not modelled 100.0 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
60d1gy8a_



not modelled 100.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
61c3gpiA_



not modelled 100.0 20 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: structure of putative nad-dependent epimerase/dehydratase2 from methylobacillus flagellatus
62d1rpna_



not modelled 100.0 10 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
63c3icpA_



not modelled 100.0 18 PDB header:isomerase
Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: crystal structure of udp-galactose 4-epimerase
64c2rh8A_



not modelled 100.0 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:anthocyanidin reductase;
PDBTitle: structure of apo anthocyanidin reductase from vitis vinifera
65d1sb8a_



not modelled 100.0 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
66d2blla1



not modelled 100.0 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
67c3a1nB_



not modelled 100.0 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:ndp-sugar epimerase;
PDBTitle: crystal structure of l-threonine dehydrogenase from2 hyperthermophilic archaeon thermoplasma volcanium
68c3ay3C_



not modelled 100.0 20 PDB header:oxidoreductase
Chain: C: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: crystal structure of glucuronic acid dehydrogeanse from2 chromohalobacter salexigens
69c3qvoA_



not modelled 100.0 24 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:nmra family protein;
PDBTitle: structure of a rossmann-fold nad(p)-binding family protein from2 shigella flexneri.
70d1udca_



not modelled 100.0 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
71c3slgB_



not modelled 100.0 12 PDB header:transferase
Chain: B: PDB Molecule:pbgp3 protein;
PDBTitle: crystal structure of pbgp3 protein from burkholderia pseudomallei
72d2q46a1



not modelled 100.0 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
73c3e8xA_



not modelled 100.0 20 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative nad-dependent epimerase/dehydratase;
PDBTitle: putative nad-dependent epimerase/dehydratase from bacillus halodurans.
74c2ggsB_



not modelled 100.0 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:273aa long hypothetical dtdp-4-dehydrorhamnose
PDBTitle: crystal structure of hypothetical dtdp-4-dehydrorhamnose2 reductase from sulfolobus tokodaii
75c3nzoB_



not modelled 100.0 12 PDB header:lyase
Chain: B: PDB Molecule:udp-n-acetylglucosamine 4,6-dehydratase;
PDBTitle: udp-n-acetylglucosamine 4,6-dehydratase from vibrio fischeri.
76c3rfxB_



not modelled 100.0 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:uronate dehydrogenase;
PDBTitle: crystal structure of uronate dehydrogenase from agrobacterium2 tumefaciens, y136a mutant complexed with nad
77d1hdoa_



not modelled 100.0 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
78d1eq2a_



not modelled 100.0 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
79c3dqpA_



not modelled 99.9 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase ylbe;
PDBTitle: crystal structure of the oxidoreductase ylbe from2 lactococcus lactis, northeast structural genomics3 consortium target kr121.
80c2x86K_



not modelled 99.9 17 PDB header:isomerase
Chain: K: PDB Molecule:adp-l-glycero-d-manno-heptose-6-epimerase;
PDBTitle: agme bound to adp-b-mannose
81c3ew7A_



not modelled 99.9 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:lmo0794 protein;
PDBTitle: crystal structure of the lmo0794 protein from listeria2 monocytogenes. northeast structural genomics consortium3 target lmr162.
82c3dhnA_



not modelled 99.9 17 PDB header:isomerase, lyase
Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: crystal structure of the putative epimerase q89z24_bactn2 from bacteroides thetaiotaomicron. northeast structural3 genomics consortium target btr310.
83d2bkaa1



not modelled 99.9 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
84d2fmua1



not modelled 99.9 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
85d2a35a1



not modelled 99.9 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
86c3h2sA_



not modelled 99.9 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative nadh-flavin reductase;
PDBTitle: crystal structure of the q03b84 protein from lactobacillus2 casei. northeast structural genomics consortium target3 lcr19.
87c2uv9B_



99.9 15 PDB header:transferase
Chain: B: PDB Molecule:fatty acid synthase alpha subunits;
PDBTitle: crystal structure of fatty acid synthase from thermomyces2 lanuginosus at 3.1 angstrom resolution. this file contains3 the alpha subunits of the fatty acid synthase. the entire4 crystal structure consists of one heterododecameric fatty5 acid synthase and is described in remark 400
88c3r6dA_



not modelled 99.9 16 PDB header:lyase, isomerase
Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: crystal structure of nad-dependent epimerase/dehydratase from2 veillonella parvula dsm 2008 with cz-methylated lysine
89c2uv8C_



not modelled 99.9 12 PDB header:transferase
Chain: C: PDB Molecule:fatty acid synthase subunit alpha (fas2);
PDBTitle: crystal structure of yeast fatty acid synthase with stalled2 acyl carrier protein at 3.1 angstrom resolution
90c2vkzC_



not modelled 99.8 15 PDB header:transferase
Chain: C: PDB Molecule:fatty acid synthase subunit alpha;
PDBTitle: structure of the cerulenin-inhibited fungal fatty acid2 synthase type i multienzyme complex
91c2vz8B_



not modelled 99.7 20 PDB header:transferase
Chain: B: PDB Molecule:fatty acid synthase;
PDBTitle: crystal structure of mammalian fatty acid synthase
92c2fr1A_



not modelled 99.6 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:erythromycin synthase, eryai;
PDBTitle: the first ketoreductase of the erythromycin synthase2 (crystal form 2)
93c2z5lA_



not modelled 99.6 19 PDB header:transferase
Chain: A: PDB Molecule:tylactone synthase starter module and modules 1
PDBTitle: the first ketoreductase of the tylosin pks
94c3mjsA_



not modelled 99.6 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:amphb;
PDBTitle: structure of a-type ketoreductases from modular polyketide synthase
95c3qp9C_



not modelled 99.6 21 PDB header:oxidoreductase
Chain: C: PDB Molecule:type i polyketide synthase pikaii;
PDBTitle: the structure of a c2-type ketoreductase from a modular polyketide2 synthase
96c3p19A_



not modelled 99.6 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative blue fluorescent protein;
PDBTitle: improved nadph-dependent blue fluorescent protein
97c2jahB_



not modelled 99.5 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:clavulanic acid dehydrogenase;
PDBTitle: biochemical and structural analysis of the clavulanic acid2 dehydeogenase (cad) from streptomyces clavuligerus
98d1mlda1



not modelled 99.5 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
99c3llsB_



not modelled 99.5 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-ketoacyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase from2 mycobacterium tuberculosis
100c3lylB_



not modelled 99.5 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-oxoacyl-(acyl-carrier-protein) reductase;
PDBTitle: structure of 3-oxoacyl-acylcarrier protein reductase, fabg2 from francisella tularensis
101c2cfcB_



not modelled 99.5 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:2-(r)-hydroxypropyl-com dehydrogenase;
PDBTitle: structural basis for stereo selectivity in the (r)- and2 (s)-hydroxypropylethane thiosulfonate dehydrogenases
102c3grkE_



not modelled 99.5 15 PDB header:oxidoreductase
Chain: E: PDB Molecule:enoyl-(acyl-carrier-protein) reductase (nadh);
PDBTitle: crystal structure of short chain dehydrogenase reductase2 sdr glucose-ribitol dehydrogenase from brucella melitensis
103c3un1D_



not modelled 99.4 15 PDB header:oxidoreductase
Chain: D: PDB Molecule:probable oxidoreductase;
PDBTitle: crystal structure of an oxidoreductase from sinorhizobium meliloti2 1021
104c3v8bC_



not modelled 99.4 16 PDB header:oxidoreductase
Chain: C: PDB Molecule:putative dehydrogenase, possibly 3-oxoacyl-[acyl-carrier
PDBTitle: crystal structure of a 3-ketoacyl-acp reductase from sinorhizobium2 meliloti 1021
105c3ioyB_



not modelled 99.4 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: structure of putative short-chain dehydrogenase (saro_0793)2 from novosphingobium aromaticivorans
106c3ppiA_



not modelled 99.4 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-hydroxyacyl-coa dehydrogenase type-2;
PDBTitle: crystal structure of 3-hydroxyacyl-coa dehydrogenase type-2 from2 mycobacterium avium
107c3gemC_



not modelled 99.4 20 PDB header:oxidoreductase
Chain: C: PDB Molecule:short chain dehydrogenase;
PDBTitle: crystal structure of short-chain dehydrogenase from pseudomonas2 syringae
108c3m1lA_



not modelled 99.4 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal strucutre of a c-terminal trunacted mutant of a putative2 ketoacyl reductase (fabg4) from mycobacterium tuberculosis h37rv at3 2.5 angstrom resolution
109d2gdza1



not modelled 99.4 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
110c3cxtA_



not modelled 99.4 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:dehydrogenase with different specificities;
PDBTitle: quaternary complex structure of gluconate 5-dehydrogenase from2 streptococcus suis type 2
111c2yutA_



not modelled 99.4 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative short-chain oxidoreductase;
PDBTitle: crystal structure of putative short-chain oxidoreductase tthb094 from2 thermus thermophilus hb8
112c2nwqA_



not modelled 99.4 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:probable short-chain dehydrogenase;
PDBTitle: short chain dehydrogenase from pseudomonas aeruginosa
113c2dteB_



not modelled 99.4 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:glucose 1-dehydrogenase related protein;
PDBTitle: structure of thermoplasma acidophilum aldohexose dehydrogenase (aldt)2 in complex with nadh
114d1iy8a_



not modelled 99.4 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
115c3i4fD_



not modelled 99.4 13 PDB header:oxidoreductase
Chain: D: PDB Molecule:3-oxoacyl-[acyl-carrier protein] reductase;
PDBTitle: structure of putative 3-oxoacyl-reductase from bacillus thuringiensis
116c3k31B_



not modelled 99.4 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:enoyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of eonyl-(acyl-carrier-protein) reductase from2 anaplasma phagocytophilum in complex with nad at 1.9a resolution
117c3toxG_



not modelled 99.4 18 PDB header:oxidoreductase
Chain: G: PDB Molecule:short chain dehydrogenase;
PDBTitle: crystal structure of a short chain dehydrogenase in complex with2 nad(p) from sinorhizobium meliloti 1021
118c2qioA_



not modelled 99.3 15 PDB header:unknown function
Chain: A: PDB Molecule:enoyl-(acyl-carrier-protein) reductase;
PDBTitle: x-ray structure of enoyl-acyl carrier protein reductase from bacillus2 anthracis with triclosan
119d1jtva_



not modelled 99.3 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
120c3oidA_



not modelled 99.3 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:enoyl-[acyl-carrier-protein] reductase [nadph];
PDBTitle: crystal structure of enoyl-acp reductases iii (fabl) from b. subtilis2 (complex with nadp and tcl)

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0