Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	L	V	T	D	L	P	A	I	F	D	Q	F	S	E	A	R	Q	T	G	F	L	T	V	M	D	L	K	E	R	G	I	P	L	V	G	T	Y	C	T	F	M	P	Q	E	I	P	M	A	A	G	A	V	V	V	S	L	C	S
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		T	S	D	E	T	I	E	E	A	E	K	D	L	P	R	N	L	C	P	L	I	K	S	S	Y	G	F	G	K	T	D	K	C	P	Y	F	Y	F	S	D	L	V	V	G	E	T	T	C	D	G	K	K	K	M	Y	E	Y	M	A	E
Secondary structure
SS confidence
Disorder			?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		F	K	P	V	H	V	M	Q	L	P	N	S	V	K	D	D	A	S	R	A	L	W	K	A	E	M	L	R	L	Q	K	T	V	E	E	R	F	G	H	E	I	S	E	D	A	L	R	D	A	I	A	L	K	N	R	E	R	R	A	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	N	F	Y	H	L	G	Q	L	N	P	P	A	L	S	G	S	D	I	L	K	V	V	Y	G	A	T	F	R	F	D	K	E	A	L	I	N	E	L	D	A	M	T	A	R	V	R	Q	Q	W	E	E	G	Q	R	L	D	P	R	P
Secondary structure
SS confidence
Disorder										?																		?																								?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		R	I	L	I	T	G	C	P	I	G	G	A	A	E	K	V	V	R	A	I	E	E	N	G	G	W	V	V	G	Y	E	N	C	T	G	A	K	A	T	E	Q	C	V	A	E	T	G	D	V	Y	D	A	L	A	D	K	Y	L	A	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		G	C	S	C	V	S	P	N	D	Q	R	L	K	M	L	S	Q	M	V	E	E	Y	Q	V	D	G	V	V	D	V	I	L	Q	A	C	H	T	Y	A	V	E	S	L	A	I	K	R	H	V	R	Q	Q	H	N	I	P	Y	I	A	I
Secondary structure
SS confidence
Disorder				?	?																																				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.
Sequence		E	T	D	Y	S	T	S	D	V	G	Q	L	S	T	R	V	A	A	F	I	E	M	L
Secondary structure
SS confidence
Disorder					?		?	?	?	?												?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3o3n chain B Region: 7 - 383 Aligned: 366 Modelled: 377 Confidence: 100.0% Identity: 22% PDB header:lyase Chain: B: PDB Molecule:beta-subunit 2-hydroxyacyl-coa dehydratase; PDBTitle: (r)-2-hydroxyisocaproyl-coa dehydratase in complex with its substrate2 (r)-2-hydroxyisocaproyl-coa Phyre2 PDB 3o3n chain A Region: 14 - 383 Aligned: 362 Modelled: 370 Confidence: 100.0% Identity: 17% PDB header:lyase Chain: A: PDB Molecule:alpha-subunit 2-hydroxyisocaproyl-coa dehydratase; PDBTitle: (r)-2-hydroxyisocaproyl-coa dehydratase in complex with its substrate2 (r)-2-hydroxyisocaproyl-coa Phyre2 PDB 2dwc chain B Region: 234 - 357 Aligned: 95 Modelled: 111 Confidence: 91.4% Identity: 17% PDB header:transferase Chain: B: PDB Molecule:433aa long hypothetical phosphoribosylglycinamide formyl PDBTitle: crystal structure of probable phosphoribosylglycinamide formyl2 transferase from pyrococcus horikoshii ot3 complexed with adp Phyre2 PDB 3ouz chain A Region: 240 - 358 Aligned: 101 Modelled: 109 Confidence: 90.4% Identity: 23% PDB header:ligase Chain: A: PDB Molecule:biotin carboxylase; PDBTitle: crystal structure of biotin carboxylase-adp complex from campylobacter2 jejuni Phyre2 PDB 2vpq chain A Region: 240 - 358 Aligned: 101 Modelled: 109 Confidence: 89.0% Identity: 17% PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase; PDBTitle: crystal structure of biotin carboxylase from s. aureus2 complexed with amppnp Phyre2 PDB 3g8c chain B Region: 240 - 358 Aligned: 101 Modelled: 119 Confidence: 87.4% Identity: 19% PDB header:ligase Chain: B: PDB Molecule:biotin carboxylase; PDBTitle: crystal stucture of biotin carboxylase in complex with2 biotin, bicarbonate, adp and mg ion Phyre2 PDB 2gpw chain C Region: 234 - 358 Aligned: 107 Modelled: 125 Confidence: 87.4% Identity: 18% PDB header:ligase Chain: C: PDB Molecule:biotin carboxylase; PDBTitle: crystal structure of the biotin carboxylase subunit, f363a2 mutant, of acetyl-coa carboxylase from escherichia coli. Phyre2 PDB 1m1n chain B Region: 46 - 371 Aligned: 237 Modelled: 248 Confidence: 86.6% Identity: 15% Fold: Chelatase-like Superfamily: "Helical backbone" metal receptor Family: Nitrogenase iron-molybdenum protein Phyre2 PDB 1kjj chain A Region: 233 - 357 Aligned: 96 Modelled: 125 Confidence: 86.1% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:phosphoribosylglycinamide formyltransferase 2; PDBTitle: crystal structure of glycniamide ribonucleotide2 transformylase in complex with mg-atp-gamma-s Phyre2 PDB 2pn1 chain A Region: 236 - 358 Aligned: 100 Modelled: 111 Confidence: 86.1% Identity: 17% PDB header:ligase Chain: A: PDB Molecule:carbamoylphosphate synthase large subunit; PDBTitle: crystal structure of carbamoylphosphate synthase large subunit (split2 gene in mj) (zp_00538348.1) from exiguobacterium sp. 255-15 at 2.00 a3 resolution Phyre2 PDB 1ulz chain A Region: 240 - 358 Aligned: 100 Modelled: 119 Confidence: 83.0% Identity: 20% PDB header:ligase Chain: A: PDB Molecule:pyruvate carboxylase n-terminal domain; PDBTitle: crystal structure of the biotin carboxylase subunit of pyruvate2 carboxylase Phyre2 PDB 3psh chain A Region: 33 - 194 Aligned: 149 Modelled: 156 Confidence: 82.8% Identity: 14% PDB header:metal transport Chain: A: PDB Molecule:protein hi_1472; PDBTitle: classification of a haemophilus influenzae abc transporter hi1470/712 through its cognate molybdate periplasmic binding protein mola (mola3 bound to molybdate) Phyre2 PDB 1n2z chain A Region: 31 - 193 Aligned: 135 Modelled: 163 Confidence: 81.4% Identity: 13% Fold: Chelatase-like Superfamily: "Helical backbone" metal receptor Family: TroA-like Phyre2 PDB 3pdi chain B Region: 108 - 360 Aligned: 154 Modelled: 180 Confidence: 79.4% Identity: 14% PDB header:protein binding Chain: B: PDB Molecule:nitrogenase mofe cofactor biosynthesis protein nifn; PDBTitle: precursor bound nifen Phyre2 PDB 1wo8 chain A domain 1 Region: 313 - 358 Aligned: 45 Modelled: 46 Confidence: 78.0% Identity: 20% Fold: Methylglyoxal synthase-like Superfamily: Methylglyoxal synthase-like Family: Methylglyoxal synthase, MgsA Phyre2 PDB 2dzd chain B Region: 240 - 358 Aligned: 101 Modelled: 119 Confidence: 76.1% Identity: 18% PDB header:ligase Chain: B: PDB Molecule:pyruvate carboxylase; PDBTitle: crystal structure of the biotin carboxylase domain of2 pyruvate carboxylase Phyre2 PDB 1nu0 chain A Region: 312 - 361 Aligned: 50 Modelled: 50 Confidence: 73.9% Identity: 6% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: Putative Holliday junction resolvase RuvX Phyre2 PDB 2r79 chain A Region: 33 - 193 Aligned: 139 Modelled: 159 Confidence: 73.7% Identity: 13% PDB header:transport protein Chain: A: PDB Molecule:periplasmic binding protein; PDBTitle: crystal structure of a periplasmic heme binding protein from2 pseudomonas aeruginosa Phyre2 PDB 1m6v chain E Region: 150 - 358 Aligned: 184 Modelled: 209 Confidence: 73.0% Identity: 19% PDB header:ligase Chain: E: PDB Molecule:carbamoyl phosphate synthetase large chain; PDBTitle: crystal structure of the g359f (small subunit) point mutant of2 carbamoyl phosphate synthetase Phyre2 PDB 1qh8 chain B Region: 45 - 371 Aligned: 237 Modelled: 257 Confidence: 71.0% Identity: 15% Fold: Chelatase-like Superfamily: "Helical backbone" metal receptor Family: Nitrogenase iron-molybdenum protein Phyre2 1 c3o3nB_ 2 c3o3nA_ 3 c2dwcB_ 4 c3ouzA_ 5 c2vpqA_ 6 c3g8cB_ 7 c2gpwC_ 8 d1m1nb_ 9 c1kjjA_ 10 c2pn1A_ 11 c1ulzA_ 12 c3pshA_ 13 d1n2za_ 14 c3pdiB_ 15 d1wo8a1 16 c2dzdB_ 17 d1nu0a_ 18 c2r79A_ 19 c1m6vE_ 20 d1qh8b_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3o3nB_ 100.0 22 PDB header:lyase Chain: B: PDB Molecule:beta-subunit 2-hydroxyacyl-coa dehydratase; PDBTitle: (r)-2-hydroxyisocaproyl-coa dehydratase in complex with its substrate2 (r)-2-hydroxyisocaproyl-coa 2 c3o3nA_ 100.0 17 PDB header:lyase Chain: A: PDB Molecule:alpha-subunit 2-hydroxyisocaproyl-coa dehydratase; PDBTitle: (r)-2-hydroxyisocaproyl-coa dehydratase in complex with its substrate2 (r)-2-hydroxyisocaproyl-coa 3 c2dwcB_ 91.4 17 PDB header:transferase Chain: B: PDB Molecule:433aa long hypothetical phosphoribosylglycinamide formyl PDBTitle: crystal structure of probable phosphoribosylglycinamide formyl2 transferase from pyrococcus horikoshii ot3 complexed with adp 4 c3ouzA_ 90.4 23 PDB header:ligase Chain: A: PDB Molecule:biotin carboxylase; PDBTitle: crystal structure of biotin carboxylase-adp complex from campylobacter2 jejuni 5 c2vpqA_ 89.0 17 PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase; PDBTitle: crystal structure of biotin carboxylase from s. aureus2 complexed with amppnp 6 c3g8cB_ 87.4 19 PDB header:ligase Chain: B: PDB Molecule:biotin carboxylase; PDBTitle: crystal stucture of biotin carboxylase in complex with2 biotin, bicarbonate, adp and mg ion 7 c2gpwC_ 87.4 18 PDB header:ligase Chain: C: PDB Molecule:biotin carboxylase; PDBTitle: crystal structure of the biotin carboxylase subunit, f363a2 mutant, of acetyl-coa carboxylase from escherichia coli. 8 d1m1nb_ 86.6 15 Fold:Chelatase-like Superfamily:"Helical backbone" metal receptor Family:Nitrogenase iron-molybdenum protein 9 c1kjjA_ 86.1 15 PDB header:transferase Chain: A: PDB Molecule:phosphoribosylglycinamide formyltransferase 2; PDBTitle: crystal structure of glycniamide ribonucleotide2 transformylase in complex with mg-atp-gamma-s 10 c2pn1A_ 86.1 17 PDB header:ligase Chain: A: PDB Molecule:carbamoylphosphate synthase large subunit; PDBTitle: crystal structure of carbamoylphosphate synthase large subunit (split2 gene in mj) (zp_00538348.1) from exiguobacterium sp. 255-15 at 2.00 a3 resolution 11 c1ulzA_ 83.0 20 PDB header:ligase Chain: A: PDB Molecule:pyruvate carboxylase n-terminal domain; PDBTitle: crystal structure of the biotin carboxylase subunit of pyruvate2 carboxylase 12 c3pshA_ 82.8 14 PDB header:metal transport Chain: A: PDB Molecule:protein hi_1472; PDBTitle: classification of a haemophilus influenzae abc transporter hi1470/712 through its cognate molybdate periplasmic binding protein mola (mola3 bound to molybdate) 13 d1n2za_ 81.4 13 Fold:Chelatase-like Superfamily:"Helical backbone" metal receptor Family:TroA-like 14 c3pdiB_ 79.4 14 PDB header:protein binding Chain: B: PDB Molecule:nitrogenase mofe cofactor biosynthesis protein nifn; PDBTitle: precursor bound nifen 15 d1wo8a1 78.0 20 Fold:Methylglyoxal synthase-like Superfamily:Methylglyoxal synthase-like Family:Methylglyoxal synthase, MgsA 16 c2dzdB_ 76.1 18 PDB header:ligase Chain: B: PDB Molecule:pyruvate carboxylase; PDBTitle: crystal structure of the biotin carboxylase domain of2 pyruvate carboxylase 17 d1nu0a_ 73.9 6 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Putative Holliday junction resolvase RuvX 18 c2r79A_ 73.7 13 PDB header:transport protein Chain: A: PDB Molecule:periplasmic binding protein; PDBTitle: crystal structure of a periplasmic heme binding protein from2 pseudomonas aeruginosa 19 c1m6vE_ 73.0 19 PDB header:ligase Chain: E: PDB Molecule:carbamoyl phosphate synthetase large chain; PDBTitle: crystal structure of the g359f (small subunit) point mutant of2 carbamoyl phosphate synthetase 20 d1qh8b_ 71.0 15 Fold:Chelatase-like Superfamily:"Helical backbone" metal receptor Family:Nitrogenase iron-molybdenum protein 21 c3gidB_ not modelled 68.0 13 PDB header:ligase Chain: B: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: the biotin carboxylase (bc) domain of human acetyl-coa2 carboxylase 2 (acc2) in complex with soraphen a 22 c3u9sE_ not modelled 67.8 15 PDB header:ligase Chain: E: PDB Molecule:methylcrotonyl-coa carboxylase, alpha-subunit; PDBTitle: crystal structure of p. aeruginosa 3-methylcrotonyl-coa carboxylase2 (mcc) 750 kd holoenzyme, coa complex 23 c2vlbC_ not modelled 67.6 11 PDB header:lyase Chain: C: PDB Molecule:arylmalonate decarboxylase; PDBTitle: structure of unliganded arylmalonate decarboxylase 24 d1m1na_ not modelled 67.0 13 Fold:Chelatase-like Superfamily:"Helical backbone" metal receptor Family:Nitrogenase iron-molybdenum protein 25 c2dgdD_ not modelled 66.1 16 PDB header:lyase Chain: D: PDB Molecule:223aa long hypothetical arylmalonate decarboxylase; PDBTitle: crystal structure of st0656, a function unknown protein from2 sulfolobus tokodaii 26 d1qh8a_ not modelled 63.5 13 Fold:Chelatase-like Superfamily:"Helical backbone" metal receptor Family:Nitrogenase iron-molybdenum protein 27 d1pq4a_ not modelled 63.2 15 Fold:Chelatase-like Superfamily:"Helical backbone" metal receptor Family:TroA-like 28 c2xdqA_ not modelled 61.2 8 PDB header:oxidoreductase Chain: A: PDB Molecule:light-independent protochlorophyllide reductase subunit n; PDBTitle: dark operative protochlorophyllide oxidoreductase (chln-2 chlb)2 complex 29 d1a9xa4 not modelled 59.9 19 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like 30 d1tr9a_ not modelled 57.3 22 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:NagZ-like 31 c3qg5D_ not modelled 57.3 10 PDB header:hydrolase Chain: D: PDB Molecule:mre11; PDBTitle: the mre11:rad50 complex forms an atp dependent molecular clamp in dna2 double-strand break repair 32 c2xecD_ not modelled 55.9 20 PDB header:isomerase Chain: D: PDB Molecule:putative maleate isomerase; PDBTitle: nocardia farcinica maleate cis-trans isomerase bound to2 tris 33 c2yvqA_ not modelled 55.2 14 PDB header:ligase Chain: A: PDB Molecule:carbamoyl-phosphate synthase; PDBTitle: crystal structure of mgs domain of carbamoyl-phosphate2 synthetase from homo sapiens 34 d2phza1 not modelled 54.6 11 Fold:Chelatase-like Superfamily:"Helical backbone" metal receptor Family:TM0189-like 35 c2phzA_ not modelled 54.6 11 PDB header:transport protein Chain: A: PDB Molecule:iron-uptake system-binding protein; PDBTitle: crystal structure of iron-uptake system-binding protein2 feua from bacillus subtilis. northeast structural genomics3 target sr580. 36 d1uf3a_ not modelled 54.6 8 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:TT1561-like 37 d1vhxa_ not modelled 54.3 20 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Putative Holliday junction resolvase RuvX 38 c3bg5C_ not modelled 54.1 16 PDB header:ligase Chain: C: PDB Molecule:pyruvate carboxylase; PDBTitle: crystal structure of staphylococcus aureus pyruvate2 carboxylase 39 c3opyH_ not modelled 53.8 20 PDB header:transferase Chain: H: PDB Molecule:6-phosphofructo-1-kinase beta-subunit; PDBTitle: crystal structure of pichia pastoris phosphofructokinase in the t-2 state 40 c3opyB_ not modelled 53.8 20 PDB header:transferase Chain: B: PDB Molecule:6-phosphofructo-1-kinase beta-subunit; PDBTitle: crystal structure of pichia pastoris phosphofructokinase in the t-2 state 41 c3s81A_ not modelled 52.6 9 PDB header:isomerase Chain: A: PDB Molecule:putative aspartate racemase; PDBTitle: crystal structure of putative aspartate racemase from salmonella2 typhimurium 42 c3ke8A_ not modelled 51.9 15 PDB header:oxidoreductase Chain: A: PDB Molecule:4-hydroxy-3-methylbut-2-enyl diphosphate PDBTitle: crystal structure of isph:hmbpp-complex 43 c2r7aC_ not modelled 51.0 14 PDB header:transport protein Chain: C: PDB Molecule:bacterial heme binding protein; PDBTitle: crystal structure of a periplasmic heme binding protein2 from shigella dysenteriae 44 c2ip4A_ not modelled 50.0 15 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylamine--glycine ligase; PDBTitle: crystal structure of glycinamide ribonucleotide synthetase from2 thermus thermophilus hb8 45 d2ajta2 not modelled 48.8 10 Fold:FucI/AraA N-terminal and middle domains Superfamily:FucI/AraA N-terminal and middle domains Family:AraA N-terminal and middle domain-like 46 d1iv0a_ not modelled 48.2 9 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Putative Holliday junction resolvase RuvX 47 c2hjwA_ not modelled 47.6 15 PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: crystal structure of the bc domain of acc2 48 d1m0wa1 not modelled 46.1 11 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:Eukaryotic glutathione synthetase, substrate-binding domain 49 d1j6xa_ not modelled 44.7 27 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:Autoinducer-2 production protein LuxS 50 c3t1iC_ not modelled 43.2 12 PDB header:hydrolase Chain: C: PDB Molecule:double-strand break repair protein mre11a; PDBTitle: crystal structure of human mre11: understanding tumorigenic mutations 51 c3gfvA_ not modelled 42.9 16 PDB header:transport protein Chain: A: PDB Molecule:uncharacterized abc transporter solute-binding PDBTitle: crystal structure of petrobactin-binding protein yclq from2 bacillu subtilis 52 c3n6rK_ not modelled 41.4 11 PDB header:ligase Chain: K: PDB Molecule:propionyl-coa carboxylase, alpha subunit; PDBTitle: crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc) 53 c3cx3A_ not modelled 41.2 15 PDB header:metal binding protein Chain: A: PDB Molecule:lipoprotein; PDBTitle: crystal structure analysis of the streptococcus pneumoniae2 adcaii protein 54 c3rxyA_ not modelled 40.8 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:nif3 protein; PDBTitle: crystal structure of nif3 superfamily protein from sphaerobacter2 thermophilus 55 c3lp8A_ not modelled 38.8 13 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylamine-glycine ligase; PDBTitle: crystal structure of phosphoribosylamine-glycine ligase from2 ehrlichia chaffeensis 56 d2j9ga2 not modelled 38.7 17 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like 57 c3md9A_ not modelled 38.4 12 PDB header:transport protein Chain: A: PDB Molecule:hemin-binding periplasmic protein hmut; PDBTitle: structure of apo form of a periplasmic heme binding protein 58 c1gsoA_ not modelled 38.0 10 PDB header:ligase Chain: A: PDB Molecule:protein (glycinamide ribonucleotide synthetase); PDBTitle: glycinamide ribonucleotide synthetase (gar-syn) from e.2 coli. 59 c2xd4A_ not modelled 37.8 10 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylamine--glycine ligase; PDBTitle: nucleotide-bound structures of bacillus subtilis glycinamide2 ribonucleotide synthetase 60 c3dloC_ not modelled 37.5 20 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:universal stress protein; PDBTitle: structure of universal stress protein from archaeoglobus fulgidus 61 d1a9xa2 not modelled 37.0 12 Fold:Methylglyoxal synthase-like Superfamily:Methylglyoxal synthase-like Family:Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain 62 d1tq8a_ not modelled 36.9 10 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:Universal stress protein-like 63 d2z3va1 not modelled 36.4 10 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:Universal stress protein-like 64 c1fuiB_ not modelled 36.0 20 PDB header:isomerase Chain: B: PDB Molecule:l-fucose isomerase; PDBTitle: l-fucose isomerase from escherichia coli 65 d1mioa_ not modelled 35.1 8 Fold:Chelatase-like Superfamily:"Helical backbone" metal receptor Family:Nitrogenase iron-molybdenum protein 66 c3eiwA_ not modelled 35.1 14 PDB header:transport protein Chain: A: PDB Molecule:htsa protein; PDBTitle: crystal structure of staphylococcus aureus lipoprotein, htsa 67 c2a7vA_ not modelled 34.2 18 PDB header:transferase Chain: A: PDB Molecule:serine hydroxymethyltransferase; PDBTitle: human mitochondrial serine hydroxymethyltransferase 2 68 d2a7va1 not modelled 34.2 18 Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:GABA-aminotransferase-like 69 c3cqyA_ not modelled 33.9 10 PDB header:transferase Chain: A: PDB Molecule:anhydro-n-acetylmuramic acid kinase; PDBTitle: crystal structure of a functionally unknown protein (so_1313) from2 shewanella oneidensis mr-1 70 c3qvjB_ not modelled 33.6 19 PDB header:isomerase Chain: B: PDB Molecule:putative hydantoin racemase; PDBTitle: allantoin racemase from klebsiella pneumoniae 71 d2auna1 not modelled 33.5 12 Fold:The "swivelling" beta/beta/alpha domain Superfamily:LD-carboxypeptidase A C-terminal domain-like Family:LD-carboxypeptidase A C-terminal domain-like 72 c3kalB_ not modelled 32.8 22 PDB header:ligase Chain: B: PDB Molecule:homoglutathione synthetase; PDBTitle: structure of homoglutathione synthetase from glycine max in2 closed conformation with homoglutathione, adp, a sulfate3 ion, and three magnesium ions bound 73 c2ys6A_ not modelled 32.8 15 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylglycinamide synthetase; PDBTitle: crystal structure of gar synthetase from geobacillus kaustophilus 74 c1w96B_ not modelled 32.6 21 PDB header:ligase Chain: B: PDB Molecule:acetyl-coenzyme a carboxylase; PDBTitle: crystal structure of biotin carboxylase domain of acetyl-2 coenzyme a carboxylase from saccharomyces cerevisiae in3 complex with soraphen a 75 c3aerB_ not modelled 32.0 14 PDB header:oxidoreductase Chain: B: PDB Molecule:light-independent protochlorophyllide reductase subunit b; PDBTitle: structure of the light-independent protochlorophyllide reductase2 catalyzing a key reduction for greening in the dark 76 c2ixaA_ not modelled 31.9 8 PDB header:hydrolase Chain: A: PDB Molecule:alpha-n-acetylgalactosaminidase; PDBTitle: a-zyme, n-acetylgalactosaminidase 77 c2ov3A_ not modelled 31.3 13 PDB header:transport protein Chain: A: PDB Molecule:periplasmic binding protein component of an abc PDBTitle: crystal structure of 138-173 znua deletion mutant plus zinc2 bound 78 c3opyE_ not modelled 31.2 16 PDB header:transferase Chain: E: PDB Molecule:6-phosphofructo-1-kinase alpha-subunit; PDBTitle: crystal structure of pichia pastoris phosphofructokinase in the t-2 state 79 c1m0tB_ not modelled 31.2 15 PDB header:ligase Chain: B: PDB Molecule:glutathione synthetase; PDBTitle: yeast glutathione synthase 80 c3hjtB_ not modelled 31.1 15 PDB header:cell adhesion, transport protein Chain: B: PDB Molecule:lmb; PDBTitle: structure of laminin binding protein (lmb) of streptococcus2 agalactiae a bifunctional protein with adhesin and metal3 transporting activity 81 c3hgmD_ not modelled 30.8 10 PDB header:signaling protein Chain: D: PDB Molecule:universal stress protein tead; PDBTitle: universal stress protein tead from the trap transporter2 teaabc of halomonas elongata 82 c2qk4A_ not modelled 30.6 20 PDB header:ligase Chain: A: PDB Molecule:trifunctional purine biosynthetic protein adenosine-3; PDBTitle: human glycinamide ribonucleotide synthetase 83 c3g23A_ not modelled 30.1 8 PDB header:hydrolase Chain: A: PDB Molecule:ld-carboxypeptidase a; PDBTitle: crystal structure of a ld-carboxypeptidase a (saro_1426) from2 novosphingobium aromaticivorans dsm at 1.89 a resolution 84 c2xdqB_ not modelled 29.7 6 PDB header:oxidoreductase Chain: B: PDB Molecule:light-independent protochlorophyllide reductase subunit b; PDBTitle: dark operative protochlorophyllide oxidoreductase (chln-2 chlb)2 complex 85 d1w3ia_ not modelled 29.1 10 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 86 c3m4xA_ not modelled 29.1 18 PDB header:transferase Chain: A: PDB Molecule:nol1/nop2/sun family protein; PDBTitle: structure of a ribosomal methyltransferase 87 d1kjqa2 not modelled 28.4 16 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like 88 c2q8pA_ not modelled 28.1 10 PDB header:metal transport Chain: A: PDB Molecule:iron-regulated surface determinant e; PDBTitle: crystal structure of selenomethionine labelled s. aureus isde2 complexed with heme 89 c3gv0A_ not modelled 27.7 13 PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator, laci family; PDBTitle: crystal structure of laci family transcription regulator from2 agrobacterium tumefaciens 90 c2xmoB_ not modelled 27.7 7 PDB header:hydrolase Chain: B: PDB Molecule:lmo2642 protein; PDBTitle: the crystal structure of lmo2642 91 d1vmda_ not modelled 27.2 20 Fold:Methylglyoxal synthase-like Superfamily:Methylglyoxal synthase-like Family:Methylglyoxal synthase, MgsA 92 c3q9cF_ not modelled 26.9 11 PDB header:hydrolase Chain: F: PDB Molecule:acetylpolyamine amidohydrolase; PDBTitle: crystal structure of h159a apah complexed with n8-acetylspermidine 93 c3ovkD_ not modelled 26.9 17 PDB header:hydrolase Chain: D: PDB Molecule:aminopeptidase p, xaa-pro dipeptidase; PDBTitle: crystal structure of an xxa-pro aminopeptidase from streptococcus2 pyogenes 94 c3opyG_ not modelled 26.8 16 PDB header:transferase Chain: G: PDB Molecule:6-phosphofructo-1-kinase alpha-subunit; PDBTitle: crystal structure of pichia pastoris phosphofructokinase in the t-2 state 95 c3m6wA_ not modelled 26.5 28 PDB header:transferase Chain: A: PDB Molecule:rrna methylase; PDBTitle: multi-site-specific 16s rrna methyltransferase rsmf from thermus2 thermophilus in space group p21212 in complex with s-adenosyl-l-3 methionine 96 c3qocD_ not modelled 26.3 24 PDB header:hydrolase Chain: D: PDB Molecule:putative metallopeptidase; PDBTitle: crystal structure of n-terminal domain (creatinase/prolidase like2 domain) of putative metallopeptidase from corynebacterium diphtheriae 97 c1b74A_ not modelled 26.3 15 PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase; PDBTitle: glutamate racemase from aquifex pyrophilus 98 c3r1fO_ not modelled 26.1 16 PDB header:transcription Chain: O: PDB Molecule:esx-1 secretion-associated regulator espr; PDBTitle: crystal structure of a key regulator of virulence in mycobacterium2 tuberculosis 99 c3il0B_ not modelled 25.7 13 PDB header:hydrolase Chain: B: PDB Molecule:aminopeptidase p; xaa-pro aminopeptidase; PDBTitle: the crystal structure of the aminopeptidase p,xaa-pro aminopeptidase2 from streptococcus thermophilus 100 d1lfpa_ not modelled 25.6 11 Fold:YebC-like Superfamily:YebC-like Family:YebC-like 101 c1k97A_ not modelled 25.5 23 PDB header:ligase Chain: A: PDB Molecule:argininosuccinate synthase; PDBTitle: crystal structure of e. coli argininosuccinate synthetase in complex2 with aspartate and citrulline 102 d1pv8a_ not modelled 25.4 18 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) 103 c2nytB_ not modelled 25.4 8 PDB header:hydrolase Chain: B: PDB Molecule:probable c->u-editing enzyme apobec-2; PDBTitle: the apobec2 crystal structure and functional implications2 for aid 104 d1jvna1 not modelled 25.2 9 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Histidine biosynthesis enzymes 105 c1zrsB_ not modelled 25.1 13 PDB header:hydrolase Chain: B: PDB Molecule:hypothetical protein; PDBTitle: wild-type ld-carboxypeptidase 106 c3pn9C_ not modelled 25.0 18 PDB header:hydrolase Chain: C: PDB Molecule:proline dipeptidase; PDBTitle: crystal structure of a proline dipeptidase from streptococcus2 pneumoniae tigr4 107 c2jfqA_ not modelled 24.6 13 PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of staphylococcus aureus glutamate2 racemase in complex with d-glutamate 108 c1lw7A_ not modelled 24.4 14 PDB header:transferase Chain: A: PDB Molecule:transcriptional regulator nadr; PDBTitle: nadr protein from haemophilus influenzae 109 c2k4mA_ not modelled 23.7 10 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0146 protein mth_1000; PDBTitle: solution nmr structure of m. thermoautotrophicum protein2 mth_1000, northeast structural genomics consortium target3 tr8 110 d3bofa2 not modelled 23.5 22 Fold:TIM beta/alpha-barrel Superfamily:Homocysteine S-methyltransferase Family:Homocysteine S-methyltransferase 111 c3menC_ not modelled 23.3 10 PDB header:hydrolase Chain: C: PDB Molecule:acetylpolyamine aminohydrolase; PDBTitle: crystal structure of acetylpolyamine aminohydrolase from burkholderia2 pseudomallei, iodide soak 112 c3dx5A_ not modelled 23.2 8 PDB header:lyase Chain: A: PDB Molecule:uncharacterized protein asbf; PDBTitle: crystal structure of the probable 3-dhs dehydratase asbf involved in2 the petrobactin synthesis from bacillus anthracis 113 c3av0A_ not modelled 22.7 11 PDB header:recombination Chain: A: PDB Molecule:dna double-strand break repair protein mre11; PDBTitle: crystal structure of mre11-rad50 bound to atp s 114 d1chma1 not modelled 22.5 12 Fold:Ribonuclease H-like motif Superfamily:Creatinase/prolidase N-terminal domain Family:Creatinase/prolidase N-terminal domain 115 c1zp9A_ not modelled 22.4 4 PDB header:transferase Chain: A: PDB Molecule:rio1 kinase; PDBTitle: crystal structure of full-legnth a.fulgidus rio1 serine kinase bound2 to atp and mn2+ ions. 116 d1t6ca1 not modelled 22.2 20 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Ppx/GppA phosphatase 117 c2frxD_ not modelled 22.0 18 PDB header:transferase Chain: D: PDB Molecule:hypothetical protein yebu; PDBTitle: crystal structure of yebu, a m5c rna methyltransferase from e.coli 118 c2jvrA_ not modelled 22.0 17 PDB header:rna binding protein Chain: A: PDB Molecule:nucleolar protein 3; PDBTitle: segmental isotope labeling of npl3p 119 d2d13a1 not modelled 21.9 17 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 120 c3hfrA_ not modelled 21.9 15 PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of glutamate racemase from listeria monocytogenes

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0