Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP76578
DateWed Jan 25 15:21:09 GMT 2012
Unique Job IDbcbb97527c014f13

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2pn5A_
Top template information
PDB header:immune system
Chain: A: PDB Molecule:thioester-containing protein i;
PDBTitle: crystal structure of tep1r
Confidence and coverage
Confidence:100.0% Coverage: 73%
1207 residues ( 73% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
1285 residues ( 78%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MKKLRVAACMLMLALAGCDNNDNAPTAVKKDAPSEVTKAASSENASSAKLSVPERQKLAQ
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   .........70.........80.........90.........100.........110.........120
Sequence  QSAGKVLTLLDLSEVQLDGAATLVLTFSIPLDPDQDFSRVIHVVDKKSGKVDGAWELSDN
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   .........130.........140.........150.........160.........170.........180
Sequence  LKELRLRHLEPKRDLIVTIGKEVKALNNATFSKDYEKTITTRDIQPSVGFASRGSLLPGK
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   .........190.........200.........210.........220.........230.........240
Sequence  VVEGLPVMALNVNNVDVNFFRVKPESLPAFISQWEYRNSLANWQSDKLLQMADLVYTGRF
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   .........250.........260.........270.........280.........290.........300
Sequence  DLNPARNTREKLLLPLGDIKPLQQAGVYLAVMNQAGRYDYSNPATLFTLSDIGVSAHRYH
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   .........310.........320.........330.........340.........350.........360
Sequence  NRLDIFTQSLENGAAQQGIEVSLLNEKGQTLTQATSDAQGHVQLENDKNAALLLARKDGQ
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   .........370.........380.........390.........400.........410.........420
Sequence  TTLLDLKLPALDLAEFNIAGAPGYSKQFFMFGPRDLYRPGETVILNGLLRDADGKALPNQ
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   .........430.........440.........450.........460.........470.........480
Sequence  PIKLDVIKPDGQVLRSVVSQPENGLYHFTWPLDSNAATGMWHIRANTGDNQYRMWDFHVE
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   .........490.........500.........510.........520.........530.........540
Sequence  DFMPERMALNLTGEKTPLTPKDEVKFSVVGYYLYGAPANGNTLQGQLFLRPLREAVSALP
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   .........550.........560.........570.........580.........590.........600
Sequence  GFEFGDIAAENLSRTLDEVQLTLDDKGRGEVSTESQWKETHSPLQVIFQGSLLESGGRPV
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   .........610.........620.........630.........640.........650.........660
Sequence  TRRAEQAIWPADALPGIRPQFASKSVYDYRTDSTVKQPIVDEGSNAAFDIVYSDAQGVKK
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   .........670.........680.........690.........700.........710.........720
Sequence  AVSGLQVRLIRERRDYYWNWSEDEGWQSQFDQKDLIENEQTLDLKADETGKVSFPVEWGA
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   .........730.........740.........750.........760.........770.........780
Sequence  YRLEVKAPNEAVSSVRFWAGYSWQDNSDGSGAVRPDRVTLKLDKASYRPGDTIKLHIAAP
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   .........790.........800.........810.........820.........830.........840
Sequence  TAGKGYAMVESSEGPLWWQEIDVRAQGLDLTIPVDKTWNRHDLYLSTLVVRPGDKSRSAT
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   .........850.........860.........870.........880.........890.........900
Sequence  PKRAVGVLHLPLGDENRRLDLALETPAKMRPNQPLTVKIKASTKNGEKPKQVNVLVSAVD
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   .........910.........920.........930.........940.........950.........960
Sequence  SGVLNITDYVTPDPWQAFFGQKRYGADIYDIYGQVIEGQGRLAALRFGGDGDELKRGGKP
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   .........970.........980.........990.........1000.........1010.........1020
Sequence  PVNHVNIVVQQALPVTLNEQGEGSVTLPIGDFNGELRVMAQAWTADDFGSNESKVIVAAP
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   .........1030.........1040.........1050.........1060.........1070.........1080
Sequence  VIAELNMPRFMASGDTSRLTLDITNLTDKPQKLNVALTASGLLELVSDSPAAVELAPGVR
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   .........1090.........1100.........1110.........1120.........1130.........1140
Sequence  TTLFIPVRALPGYGDGEIQATISGLALPGETVADQHKQWKIGVRPAFPAQTVNYGTALQP
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   .........1150.........1160.........1170.........1180.........1190.........1200
Sequence  GETWAIPADGLQNFSPVTLEGQLLLSGKPPLNIARYIKELKAYPYGCLEQTASGLFPSLY
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   .........1210.........1220.........1230.........1240.........1250.........1260
Sequence  TNAAQLQALGIKGDSDEKRRASVDIGISRLLQMQRDNGGFALWDKNGDEEYWLTAYVMDF
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   .........1270.........1280.........1290.........1300.........1310.........1320
Sequence  LVRAGEQGYSVPTDAINRGNERLLRYLQDPGMMSIPYADNLKASKFAVQSYAALVLARQQ
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   .........1330.........1340.........1350.........1360.........1370.........1380
Sequence  KAPLGALREIWEHRADAASGLPLLQLGVALKTMGDATRGEEAIALALKTPRNSDERIWLG
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   .........1390.........1400.........1410.........1420.........1430.........1440
Sequence  DYGSSLRDNALMLSLLEENKLLPDEQYTLLNTLSQQAFGERWLSTQESNALFLAARTIQD
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   .........1450.........1460.........1470.........1480.........1490.........1500
Sequence  LPGKWQAQTSFSAEQLTGEKAQNSNLNSDQLVTLQVSNSGDQPLWLRMDASGYPQSAPLP
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   .........1510.........1520.........1530.........1540.........1550.........1560
Sequence  ANNVLQIERHILGTDGKSKSLDSLRSGDLVLVWLQVKASNSVPDALVVDLLPAGLELENQ
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   .........1570.........1580.........1590.........1600.........1610.........1620
Sequence  NLANGSASLEQSGGEVQNLLNQMQQASIKHIEFRDDRFVAAVAVDEYQPVTLVYLARAVT
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   .........1630.........1640.........1650...
Sequence  PGTYQVPQPMVESMYVPQWRATGAAEDLLIVRP
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2pn5 chain A

3D model

Region: 292 - 1642
Aligned: 1207
Modelled: 1250
Confidence: 100.0%
Identity: 14%
PDB header:immune system
Chain: A: PDB Molecule:thioester-containing protein i;
PDBTitle: crystal structure of tep1r

Phyre2

PDB 3cu7 chain A

3D model

Region: 300 - 1643
Aligned: 1242
Modelled: 1276
Confidence: 100.0%
Identity: 14%
PDB header:immune system
Chain: A: PDB Molecule:complement c5;
PDBTitle: human complement component 5

Phyre2

PDB 2b39 chain B

3D model

Region: 363 - 1642
Aligned: 1180
Modelled: 1206
Confidence: 100.0%
Identity: 16%
PDB header:immune system
Chain: B: PDB Molecule:c3;
PDBTitle: structure of mammalian c3 with an intact thioester at 3a resolution

Phyre2

PDB 2a73 chain B

3D model

Region: 950 - 1642
Aligned: 665
Modelled: 673
Confidence: 100.0%
Identity: 15%
PDB header:immune system
Chain: B: PDB Molecule:complement c3;
PDBTitle: human complement component c3

Phyre2

PDB 3g6j chain B

3D model

Region: 950 - 1642
Aligned: 657
Modelled: 669
Confidence: 100.0%
Identity: 15%
PDB header:immune system
Chain: B: PDB Molecule:complement c3 alpha chain;
PDBTitle: c3b in complex with a c3b specific fab

Phyre2

PDB 3pvm chain B

3D model

Region: 388 - 1641
Aligned: 877
Modelled: 902
Confidence: 100.0%
Identity: 18%
PDB header:immune system
Chain: B: PDB Molecule:cobra venom factor;
PDBTitle: structure of complement c5 in complex with cvf

Phyre2

PDB 1hzf chain A

3D model

Region: 1174 - 1442
Aligned: 267
Modelled: 269
Confidence: 100.0%
Identity: 19%
Fold: alpha/alpha toroid
Superfamily: Terpenoid cyclases/Protein prenyltransferases
Family: Complement components

Phyre2

PDB 1hzf chain A

3D model

Region: 1174 - 1442
Aligned: 267
Modelled: 269
Confidence: 100.0%
Identity: 19%
PDB header:immune system
Chain: A: PDB Molecule:complement factor c4a;
PDBTitle: c4adg fragment of human complement factor c4a

Phyre2

PDB 1c3d chain A

3D model

Region: 1174 - 1441
Aligned: 263
Modelled: 266
Confidence: 100.0%
Identity: 19%
Fold: alpha/alpha toroid
Superfamily: Terpenoid cyclases/Protein prenyltransferases
Family: Complement components

Phyre2

PDB 3hrz chain A

3D model

Region: 296 - 918
Aligned: 536
Modelled: 556
Confidence: 100.0%
Identity: 13%
PDB header:immune system
Chain: A: PDB Molecule:cobra venom factor;
PDBTitle: cobra venom factor (cvf) in complex with human factor b

Phyre2

PDB 1qqf chain A

3D model

Region: 1188 - 1441
Aligned: 249
Modelled: 254
Confidence: 100.0%
Identity: 16%
Fold: alpha/alpha toroid
Superfamily: Terpenoid cyclases/Protein prenyltransferases
Family: Complement components

Phyre2

PDB 2qki chain A

3D model

Region: 296 - 918
Aligned: 549
Modelled: 564
Confidence: 100.0%
Identity: 14%
PDB header:immune system/hydrolase inhibitor
Chain: A: PDB Molecule:complement c3;
PDBTitle: human c3c in complex with the inhibitor compstatin

Phyre2

PDB 3hs0 chain B

3D model

Region: 952 - 1169
Aligned: 213
Modelled: 218
Confidence: 100.0%
Identity: 14%
PDB header:immune system
Chain: B: PDB Molecule:cobra venom factor;
PDBTitle: cobra venom factor (cvf) in complex with human factor b

Phyre2

PDB 2a74 chain B

3D model

Region: 950 - 1126
Aligned: 172
Modelled: 177
Confidence: 99.9%
Identity: 11%
PDB header:immune system
Chain: B: PDB Molecule:complement component c3c;
PDBTitle: human complement component c3c

Phyre2

PDB 2p9r chain A

3D model

Region: 388 - 485
Aligned: 98
Modelled: 98
Confidence: 99.7%
Identity: 23%
PDB header:signaling protein
Chain: A: PDB Molecule:alpha-2-macroglobulin;
PDBTitle: human alpha2-macroglogulin is composed of multiple domains,2 as predicted by homology with complement component c3

Phyre2

PDB 2sqc chain A domain 1

3D model

Region: 1220 - 1438
Aligned: 213
Modelled: 219
Confidence: 99.6%
Identity: 16%
Fold: alpha/alpha toroid
Superfamily: Terpenoid cyclases/Protein prenyltransferases
Family: Terpene synthases

Phyre2

PDB 3hrz chain C

3D model

Region: 1446 - 1641
Aligned: 173
Modelled: 196
Confidence: 99.6%
Identity: 10%
PDB header:immune system
Chain: C: PDB Molecule:cobra venom factor;
PDBTitle: cobra venom factor (cvf) in complex with human factor b

Phyre2

PDB 1o79 chain A

3D model

Region: 1205 - 1441
Aligned: 196
Modelled: 199
Confidence: 99.6%
Identity: 20%
PDB header:isomerase
Chain: A: PDB Molecule:squalene--hopene cyclase;
PDBTitle: structures of human oxidosqualene cyclase inhibitors bound2 to a homolgous enzyme

Phyre2

PDB 1w6k chain A

3D model

Region: 1200 - 1447
Aligned: 207
Modelled: 207
Confidence: 99.4%
Identity: 18%
PDB header:isomerase
Chain: A: PDB Molecule:lanosterol synthase;
PDBTitle: structure of human osc in complex with lanosterol

Phyre2

PDB 1edy chain A

3D model

Region: 1504 - 1641
Aligned: 116
Modelled: 121
Confidence: 99.4%
Identity: 15%
Fold: Common fold of diphtheria toxin/transcription factors/cytochrome f
Superfamily: Alpha-macroglobulin receptor domain
Family: Alpha-macroglobulin receptor domain

Phyre2
1

c2pn5A_
2

c3cu7A_
3

c2b39B_
4

c2a73B_
5

c3g6jB_
6

c3pvmB_
7

d1hzfa_
8

c1hzfA_
9

d1c3da_
10

c3hrzA_
11

d1qqfa_
12

c2qkiA_
13

c3hs0B_
14

c2a74B_
15

c2p9rA_
16

d2sqca1
17

c3hrzC_
18

c1o79A_
19

c1w6kA_
20

d1edya_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2pn5A_



100.0 14 PDB header:immune system
Chain: A: PDB Molecule:thioester-containing protein i;
PDBTitle: crystal structure of tep1r
2c3cu7A_



100.0 14 PDB header:immune system
Chain: A: PDB Molecule:complement c5;
PDBTitle: human complement component 5
3c2b39B_



100.0 16 PDB header:immune system
Chain: B: PDB Molecule:c3;
PDBTitle: structure of mammalian c3 with an intact thioester at 3a resolution
4c2a73B_



100.0 15 PDB header:immune system
Chain: B: PDB Molecule:complement c3;
PDBTitle: human complement component c3
5c3g6jB_



100.0 15 PDB header:immune system
Chain: B: PDB Molecule:complement c3 alpha chain;
PDBTitle: c3b in complex with a c3b specific fab
6c3pvmB_



100.0 18 PDB header:immune system
Chain: B: PDB Molecule:cobra venom factor;
PDBTitle: structure of complement c5 in complex with cvf
7d1hzfa_



100.0 19 Fold:alpha/alpha toroid
Superfamily:Terpenoid cyclases/Protein prenyltransferases
Family:Complement components
8c1hzfA_



100.0 19 PDB header:immune system
Chain: A: PDB Molecule:complement factor c4a;
PDBTitle: c4adg fragment of human complement factor c4a
9d1c3da_



100.0 19 Fold:alpha/alpha toroid
Superfamily:Terpenoid cyclases/Protein prenyltransferases
Family:Complement components
10c3hrzA_



100.0 13 PDB header:immune system
Chain: A: PDB Molecule:cobra venom factor;
PDBTitle: cobra venom factor (cvf) in complex with human factor b
11d1qqfa_



100.0 16 Fold:alpha/alpha toroid
Superfamily:Terpenoid cyclases/Protein prenyltransferases
Family:Complement components
12c2qkiA_



100.0 14 PDB header:immune system/hydrolase inhibitor
Chain: A: PDB Molecule:complement c3;
PDBTitle: human c3c in complex with the inhibitor compstatin
13c3hs0B_



100.0 14 PDB header:immune system
Chain: B: PDB Molecule:cobra venom factor;
PDBTitle: cobra venom factor (cvf) in complex with human factor b
14c2a74B_



99.9 11 PDB header:immune system
Chain: B: PDB Molecule:complement component c3c;
PDBTitle: human complement component c3c
15c2p9rA_



99.7 23 PDB header:signaling protein
Chain: A: PDB Molecule:alpha-2-macroglobulin;
PDBTitle: human alpha2-macroglogulin is composed of multiple domains,2 as predicted by homology with complement component c3
16d2sqca1



99.6 16 Fold:alpha/alpha toroid
Superfamily:Terpenoid cyclases/Protein prenyltransferases
Family:Terpene synthases
17c3hrzC_



99.6 10 PDB header:immune system
Chain: C: PDB Molecule:cobra venom factor;
PDBTitle: cobra venom factor (cvf) in complex with human factor b
18c1o79A_



99.6 20 PDB header:isomerase
Chain: A: PDB Molecule:squalene--hopene cyclase;
PDBTitle: structures of human oxidosqualene cyclase inhibitors bound2 to a homolgous enzyme
19c1w6kA_



99.4 18 PDB header:isomerase
Chain: A: PDB Molecule:lanosterol synthase;
PDBTitle: structure of human osc in complex with lanosterol
20d1edya_



99.4 15 Fold:Common fold of diphtheria toxin/transcription factors/cytochrome f
Superfamily:Alpha-macroglobulin receptor domain
Family:Alpha-macroglobulin receptor domain
21d1ayoa_



not modelled 99.4 16 Fold:Common fold of diphtheria toxin/transcription factors/cytochrome f
Superfamily:Alpha-macroglobulin receptor domain
Family:Alpha-macroglobulin receptor domain
22d1bv8a_



not modelled 99.4 14 Fold:Common fold of diphtheria toxin/transcription factors/cytochrome f
Superfamily:Alpha-macroglobulin receptor domain
Family:Alpha-macroglobulin receptor domain
23d3es6b1



not modelled 99.4 11 Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:SVA-like
24d2sqca2



not modelled 99.3 15 Fold:alpha/alpha toroid
Superfamily:Terpenoid cyclases/Protein prenyltransferases
Family:Terpene synthases
25d1w6ka1



not modelled 99.3 18 Fold:alpha/alpha toroid
Superfamily:Terpenoid cyclases/Protein prenyltransferases
Family:Terpene synthases
26c2qkiC_



not modelled 99.2 7 PDB header:immune system/hydrolase inhibitor
Chain: C: PDB Molecule:complement c3;
PDBTitle: human c3c in complex with the inhibitor compstatin
27d3dssb1



not modelled 98.6 17 Fold:alpha/alpha toroid
Superfamily:Terpenoid cyclases/Protein prenyltransferases
Family:Protein prenyltransferases
28c3e37B_



not modelled 98.2 13 PDB header:transferase
Chain: B: PDB Molecule:protein farnesyltransferase subunit beta;
PDBTitle: protein farnesyltransferase complexed with bisubstrate2 ethylenediamine scaffold inhibitor 5
29d2h6fb1



not modelled 98.1 13 Fold:alpha/alpha toroid
Superfamily:Terpenoid cyclases/Protein prenyltransferases
Family:Protein prenyltransferases
30c1cwvA_



not modelled 97.8 10 PDB header:structural protein
Chain: A: PDB Molecule:invasin;
PDBTitle: crystal structure of invasin: a bacterial integrin-binding protein
31c3q7aB_



not modelled 97.7 14 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:farnesyltransferase beta subunit;
PDBTitle: cryptococcus neoformans protein farnesyltransferase in complex with2 fpp and l-778,123
32c2pmvB_



not modelled 97.4 11 PDB header:transport protein
Chain: B: PDB Molecule:gastric intrinsic factor;
PDBTitle: crystal structure of human intrinsic factor- cobalamin complex at 2.62 a resolution
33c1tnuL_



not modelled 97.4 12 PDB header:transferase
Chain: L: PDB Molecule:geranylgeranyl transferase type i beta subunit;
PDBTitle: rat protein geranylgeranyltransferase type-i complexed with2 a ggpp analog and a gcincckvl peptide derived from rhob
34d1n4qb_



not modelled 97.4 12 Fold:alpha/alpha toroid
Superfamily:Terpenoid cyclases/Protein prenyltransferases
Family:Protein prenyltransferases
35d1w6ka2



not modelled 97.1 19 Fold:alpha/alpha toroid
Superfamily:Terpenoid cyclases/Protein prenyltransferases
Family:Terpene synthases
36c3draB_



not modelled 97.0 10 PDB header:transferase
Chain: B: PDB Molecule:geranylgeranyltransferase type i beta subunit;
PDBTitle: candida albicans protein geranylgeranyltransferase-i2 complexed with ggpp
37d1w8oa1



not modelled 96.8 17 Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:E-set domains of sugar-utilizing enzymes
38c1l9mB_



not modelled 96.6 15 PDB header:transferase
Chain: B: PDB Molecule:protein-glutamine glutamyltransferase e3;
PDBTitle: three-dimensional structure of the human transglutaminase 32 enzyme: binding of calcium ions change structure for3 activation
39d1r76a_



not modelled 96.5 23 Fold:alpha/alpha toroid
Superfamily:Family 10 polysaccharide lyase
Family:Family 10 polysaccharide lyase
40d1gxma_



not modelled 96.5 23 Fold:alpha/alpha toroid
Superfamily:Family 10 polysaccharide lyase
Family:Family 10 polysaccharide lyase
41c2v3nA_



not modelled 96.1 13 PDB header:transport protein
Chain: A: PDB Molecule:transcobalamin-2;
PDBTitle: crystallographic analysis of upper axial ligand2 substitutions in cobalamin bound to transcobalamin
42d2afaa1



not modelled 95.1 17 Fold:alpha/alpha toroid
Superfamily:Six-hairpin glycosidases
Family:N-acylglucosamine (NAG) epimerase
43c2kl6A_



not modelled 94.6 19 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: solution nmr structure of the cardb domain of pf1109 from2 pyrococcus furiosus. northeast structural genomics3 consortium target pfr193a
44c3e8vA_



not modelled 93.1 21 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:possible transglutaminase-family protein;
PDBTitle: crystal structure of a possible transglutaminase-family2 protein proteolytic fragment from bacteroides fragilis
45d1cwva1



not modelled 92.5 11 Fold:Immunoglobulin-like beta-sandwich
Superfamily:Invasin/intimin cell-adhesion fragments
Family:Invasin/intimin cell-adhesion fragments
46c1wlhA_



not modelled 91.7 12 PDB header:structural protein
Chain: A: PDB Molecule:gelation factor;
PDBTitle: molecular structure of the rod domain of dictyostelium2 filamin
47d1h8la1



not modelled 91.5 13 Fold:Prealbumin-like
Superfamily:Carboxypeptidase regulatory domain-like
Family:Carboxypeptidase regulatory domain
48c3irpX_



not modelled 90.5 36 PDB header:cell adhesion
Chain: X: PDB Molecule:uro-adherence factor a;
PDBTitle: crystal structure of functional region of uafa from staphylococcus2 saprophyticus at 1.50 angstrom resolution
49c3kptA_



not modelled 89.9 18 PDB header:cell adhesion
Chain: A: PDB Molecule:collagen adhesion protein;
PDBTitle: crystal structure of bcpa, the major pilin subunit of2 bacillus cereus
50c2h0eA_



not modelled 89.4 12 PDB header:hydrolase
Chain: A: PDB Molecule:transthyretin-like protein pucm;
PDBTitle: crystal structure of pucm in the absence of substrate
51d1qfha1



not modelled 89.3 18 Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:Filamin repeat (rod domain)
52d1f00i1



not modelled 88.9 10 Fold:Immunoglobulin-like beta-sandwich
Superfamily:Invasin/intimin cell-adhesion fragments
Family:Invasin/intimin cell-adhesion fragments
53c1kv3F_



not modelled 88.8 9 PDB header:transferase
Chain: F: PDB Molecule:protein-glutamine gamma-glutamyltransferase;
PDBTitle: human tissue transglutaminase in gdp bound form
54c2l0dA_



not modelled 88.8 14 PDB header:cell adhesion
Chain: A: PDB Molecule:cell surface protein;
PDBTitle: solution nmr structure of putative cell surface protein ma_4588 (272-2 376 domain) from methanosarcina acetivorans, northeast structural3 genomics consortium target mvr254a
55c3qvaB_



not modelled 87.5 33 PDB header:hydrolase
Chain: B: PDB Molecule:transthyretin-like protein;
PDBTitle: structure of klebsiella pneumoniae 5-hydroxyisourate hydrolase
56c1g0dA_



not modelled 86.6 15 PDB header:transferase
Chain: A: PDB Molecule:protein-glutamine gamma-glutamyltransferase;
PDBTitle: crystal structure of red sea bream transglutaminase
57d1cwva2



not modelled 86.3 8 Fold:Immunoglobulin-like beta-sandwich
Superfamily:Invasin/intimin cell-adhesion fragments
Family:Invasin/intimin cell-adhesion fragments
58c2pz4A_



not modelled 85.2 16 PDB header:cell adhesion
Chain: A: PDB Molecule:protein gbs052;
PDBTitle: crystal structure of spab (gbs52), the minor pilin in gram-positive2 pathogen streptococcus agalactiae
59d1kgia_



not modelled 85.0 11 Fold:Prealbumin-like
Superfamily:Transthyretin (synonym: prealbumin)
Family:Transthyretin (synonym: prealbumin)
60d2q3za3



not modelled 84.8 8 Fold:Immunoglobulin-like beta-sandwich
Superfamily:Transglutaminase, two C-terminal domains
Family:Transglutaminase, two C-terminal domains
61c1h8lA_



not modelled 84.8 13 PDB header:carboxypeptidase
Chain: A: PDB Molecule:carboxypeptidase gp180 residues 503-882;
PDBTitle: duck carboxypeptidase d domain ii in complex with gemsa
62d1uwya1



not modelled 84.6 13 Fold:Prealbumin-like
Superfamily:Carboxypeptidase regulatory domain-like
Family:Carboxypeptidase regulatory domain
63d2diba1



not modelled 84.4 17 Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:Filamin repeat (rod domain)
64c2r39A_



not modelled 83.9 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:fixg-related protein;
PDBTitle: crystal structure of fixg-related protein from vibrio parahaemolyticus
65c3mn8A_



not modelled 83.4 10 PDB header:hydrolase
Chain: A: PDB Molecule:lp15968p;
PDBTitle: structure of drosophila melanogaster carboxypeptidase d isoform 1b2 short
66c1uwyA_



not modelled 82.9 11 PDB header:hydrolase
Chain: A: PDB Molecule:carboxypeptidase m;
PDBTitle: crystal structure of human carboxypeptidase m
67c2h1xB_



not modelled 82.7 18 PDB header:hydrolase
Chain: B: PDB Molecule:5-hydroxyisourate hydrolase (formerly known as
PDBTitle: crystal structure of 5-hydroxyisourate hydrolase (formerly2 known as trp, transthyretin related protein)
68d1vjja3



not modelled 82.6 18 Fold:Immunoglobulin-like beta-sandwich
Superfamily:Transglutaminase, two C-terminal domains
Family:Transglutaminase, two C-terminal domains
69d1f86a_



not modelled 82.6 13 Fold:Prealbumin-like
Superfamily:Transthyretin (synonym: prealbumin)
Family:Transthyretin (synonym: prealbumin)
70d2e9ia1



not modelled 82.3 14 Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:Filamin repeat (rod domain)
71c1f13A_



not modelled 81.7 10 PDB header:coagulation factor
Chain: A: PDB Molecule:cellular coagulation factor xiii zymogen;
PDBTitle: recombinant human cellular coagulation factor xiii
72c3saeA_



not modelled 81.7 9 PDB header:lyase
Chain: A: PDB Molecule:alpha-bisabolene synthase;
PDBTitle: structure of a three-domain sesquiterpene synthase: a prospective2 target for advanced biofuels production
73d1tfpa_



not modelled 81.3 16 Fold:Prealbumin-like
Superfamily:Transthyretin (synonym: prealbumin)
Family:Transthyretin (synonym: prealbumin)
74d1ttaa_



not modelled 80.8 11 Fold:Prealbumin-like
Superfamily:Transthyretin (synonym: prealbumin)
Family:Transthyretin (synonym: prealbumin)
75d1g0da3



not modelled 80.7 13 Fold:Immunoglobulin-like beta-sandwich
Superfamily:Transglutaminase, two C-terminal domains
Family:Transglutaminase, two C-terminal domains
76d1oo2a_



not modelled 80.6 18 Fold:Prealbumin-like
Superfamily:Transthyretin (synonym: prealbumin)
Family:Transthyretin (synonym: prealbumin)
77c2k7pA_



not modelled 80.4 14 PDB header:structural protein
Chain: A: PDB Molecule:filamin-a;
PDBTitle: filamin a ig-like domains 16-17
78c2gpzC_



not modelled 80.2 24 PDB header:hydrolase
Chain: C: PDB Molecule:transthyretin-like protein;
PDBTitle: transthyretin-like protein from salmonella dublin
79d1vjja2



not modelled 79.8 21 Fold:Immunoglobulin-like beta-sandwich
Superfamily:Transglutaminase, two C-terminal domains
Family:Transglutaminase, two C-terminal domains
80d1ex0a2



not modelled 77.5 11 Fold:Immunoglobulin-like beta-sandwich
Superfamily:Transglutaminase, two C-terminal domains
Family:Transglutaminase, two C-terminal domains
81d2q3za2



not modelled 77.4 12 Fold:Immunoglobulin-like beta-sandwich
Superfamily:Transglutaminase, two C-terminal domains
Family:Transglutaminase, two C-terminal domains
82d2d7ma1



not modelled 77.0 18 Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:Filamin repeat (rod domain)
83d1qfha2



not modelled 76.6 10 Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:Filamin repeat (rod domain)
84d1ex0a3



not modelled 76.2 17 Fold:Immunoglobulin-like beta-sandwich
Superfamily:Transglutaminase, two C-terminal domains
Family:Transglutaminase, two C-terminal domains
85c2xzzA_



not modelled 74.1 14 PDB header:transferase
Chain: A: PDB Molecule:protein-glutamine gamma-glutamyltransferase k;
PDBTitle: crystal structure of the human transglutaminase 1 beta-barrel domain
86c2nsmA_



not modelled 73.5 20 PDB header:hydrolase
Chain: A: PDB Molecule:carboxypeptidase n catalytic chain;
PDBTitle: crystal structure of the human carboxypeptidase n (kininase i)2 catalytic domain
87d2dmca1



not modelled 71.9 12 Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:Filamin repeat (rod domain)
88c2ww8A_



not modelled 71.8 24 PDB header:cell adhesion
Chain: A: PDB Molecule:cell wall surface anchor family protein;
PDBTitle: structure of the pilus adhesin (rrga) from streptococcus2 pneumoniae
89c2e9jA_



not modelled 71.7 21 PDB header:structural protein
Chain: A: PDB Molecule:filamin-b;
PDBTitle: solution structure of the 14th filamin domain from human2 filamin-b
90d2dmba1



not modelled 70.9 25 Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:Filamin repeat (rod domain)
91c2k7qA_



not modelled 69.3 13 PDB header:structural protein
Chain: A: PDB Molecule:filamin-a;
PDBTitle: filamin a ig-like domains 18-19
92d1cwva3



not modelled 67.9 8 Fold:Immunoglobulin-like beta-sandwich
Superfamily:Invasin/intimin cell-adhesion fragments
Family:Invasin/intimin cell-adhesion fragments
93d1v05a_



not modelled 67.4 17 Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:Filamin repeat (rod domain)
94d1g0da2



not modelled 67.0 9 Fold:Immunoglobulin-like beta-sandwich
Superfamily:Transglutaminase, two C-terminal domains
Family:Transglutaminase, two C-terminal domains
95c3k11A_



not modelled 67.0 13 PDB header:hydrolase
Chain: A: PDB Molecule:putative glycosyl hydrolase;
PDBTitle: crystal structure of putative glycosyl hydrolase (np_813087.1) from2 bacteroides thetaiotaomicron vpi-5482 at 1.80 a resolution
96c1ksrA_



not modelled 65.8 15 PDB header:actin binding protein
Chain: A: PDB Molecule:gelation factor;
PDBTitle: the repeating segments of the f-actin cross-linking2 gelation factor (abp-120) have an immunoglobulin fold, nmr,3 20 structures
97c1qfhB_



not modelled 65.1 13 PDB header:actin binding protein
Chain: B: PDB Molecule:protein (gelation factor);
PDBTitle: dimerization of gelation factor from dictyostelium2 discoideum: crystal structure of rod domains 5 and 6
98c3n6yA_



not modelled 65.1 18 PDB header:unknown function
Chain: A: PDB Molecule:immunoglobulin-like protein;
PDBTitle: crystal structure of an immunoglobulin-like protein (pa1606) from2 pseudomonas aeruginosa at 1.50 a resolution
99c2kutA_



not modelled 63.3 11 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: solution structure of gmr58a from geobacter metallireducens.2 northeast structural genomics consortium target gmr58a
100c3ogrA_



not modelled 62.1 20 PDB header:hydrolase
Chain: A: PDB Molecule:beta-galactosidase;
PDBTitle: complex structure of beta-galactosidase from trichoderma reesei with2 galactose
101c1xc6A_



not modelled 62.0 18 PDB header:hydrolase
Chain: A: PDB Molecule:beta-galactosidase;
PDBTitle: native structure of beta-galactosidase from penicillium sp. in complex2 with galactose
102c3qe5A_



not modelled 60.5 14 PDB header:cell adhesion
Chain: A: PDB Molecule:major cell-surface adhesin pac;
PDBTitle: complete structure of streptococcus mutans antigen i/ii carboxy-2 terminus
103d2dj4a1



not modelled 60.1 19 Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:Filamin repeat (rod domain)
104d1vjja1



not modelled 59.8 6 Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:Transglutaminase N-terminal domain
105c2ds4A_



not modelled 59.4 17 PDB header:protein binding
Chain: A: PDB Molecule:tripartite motif protein 45;
PDBTitle: solution structure of the filamin domain from human2 tripartite motif protein 45
106d1wlha1



not modelled 58.3 16 Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:Filamin repeat (rod domain)
107c3pmmA_



not modelled 56.5 16 PDB header:hydrolase
Chain: A: PDB Molecule:putative cytoplasmic protein;
PDBTitle: the crystal structure of a possible member of gh105 family from2 klebsiella pneumoniae subsp. pneumoniae mgh 78578
108c2zxcA_



not modelled 54.5 11 PDB header:hydrolase
Chain: A: PDB Molecule:neutral ceramidase;
PDBTitle: seramidase complexed with c2
109d2d7na1



not modelled 54.3 13 Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:Filamin repeat (rod domain)
110d2diaa1



not modelled 52.3 21 Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:Filamin repeat (rod domain)
111c2x5pA_



not modelled 51.8 15 PDB header:protein binding
Chain: A: PDB Molecule:fibronectin binding protein;
PDBTitle: crystal structure of the streptococcus pyogenes fibronectin binding2 protein fbab-b
112c1f00I_



not modelled 49.2 10 PDB header:cell adhesion
Chain: I: PDB Molecule:intimin;
PDBTitle: crystal structure of c-terminal 282-residue fragment of2 enteropathogenic e. coli intimin
113c2di7A_



not modelled 49.2 9 PDB header:structural protein
Chain: A: PDB Molecule:bk158_1;
PDBTitle: solution structure of the filamin domain from human bk158_12 protein
114d1g4ma2



not modelled 49.1 14 Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:Arrestin/Vps26-like
115d2d7pa1



not modelled 48.9 18 Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:Filamin repeat (rod domain)
116c2e6jA_



not modelled 48.0 15 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hydin protein;
PDBTitle: solution structure of the c-terminal papd-like domain from2 human hydin protein
117d1ayra2



not modelled 47.4 9 Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:Arrestin/Vps26-like
118c2okmA_



not modelled 46.1 11 PDB header:cell adhesion
Chain: A: PDB Molecule:collagen adhesin;
PDBTitle: crystal structure of ace19, the collagen binding subdomain2 of enterococcus faecalis surface protein ace
119c2z1pA_



not modelled 45.4 12 PDB header:cell adhesion
Chain: A: PDB Molecule:collagen adhesin protein;
PDBTitle: the enterococcus faecalis mscramm ace binds its ligands by2 the collagen hug model
120c3n9tA_



not modelled 45.0 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:pnpc;
PDBTitle: cryatal structure of hydroxyquinol 1,2-dioxygenase from pseudomonas2 putida dll-e4

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0