Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	P	K	L	R	L	I	G	L	T	L	L	A	L	S	A	T	A	V	S	H	A	E	E	T	R	Y	V	S	D	E	L	N	T	W	V	R	S	G	P	G	D	H	Y	R	L	V	G	T	V	N	A	G	E	E	V	T	L	L	Q
Secondary structure
SS confidence
Disorder		?	?	?	?												?	?	?			?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		T	D	A	N	T	N	Y	A	Q	V	K	D	S	S	G	R	T	A	W	I	P	L	K	Q	L	S	T	E	P	S	L	R	S	R	V	P	D	L	E	N	Q	V	K	T	L	T	D	K	L	T	N	I	D	N	T	W	N	Q	R	T
Secondary structure
SS confidence
Disorder					?											?	?	?	?			?	?				?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	E	M	Q	Q	K	V	A	Q	S	D	S	V	I	N	G	L	K	E	E	N	Q	K	L	K	N	E	L	I	V	A	Q	K	K	V	D	A	A	S	V	Q	L	D	D	K	Q	R	T	I	I	M	Q	W	F	M	Y	G	G	G	V
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.
Sequence		L	G	L	G	L	L	L	G	L	V	L	P	H	L	I	P	S	R	K	R	K	D	R	W	M	N
Secondary structure
SS confidence
Disorder													?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2kt8 chain A Region: 22 - 86 Aligned: 62 Modelled: 63 Confidence: 99.0% Identity: 18% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:probable surface protein; PDBTitle: solution nmr structure of the cpe1231(468-535) protein from2 clostridium perfringens, northeast structural genomics3 consortium target cpr82b Phyre2 PDB 2krs chain A Region: 28 - 91 Aligned: 61 Modelled: 62 Confidence: 98.9% Identity: 18% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:probable enterotoxin; PDBTitle: solution nmr structure of sh3 domain from cpf_0587 (fragment2 415-479) from clostridium perfringens. northeast structural3 genomics consortium (nesg) target cpr74a. Phyre2 PDB 2kyb chain A Region: 24 - 85 Aligned: 59 Modelled: 60 Confidence: 98.6% Identity: 15% PDB header:toxin Chain: A: PDB Molecule:mannosyl-glycoprotein endo-beta-n-acetylglucosamidase PDBTitle: solution structure of cpr82g from clostridium perfringens. north east2 structural genomics consortium target cpr82g Phyre2 PDB 2kq8 chain A Region: 27 - 90 Aligned: 61 Modelled: 64 Confidence: 98.6% Identity: 28% PDB header:hydrolase Chain: A: PDB Molecule:cell wall hydrolase; PDBTitle: solution nmr structure of a domain from bt9727_4915 from2 bacillus thuringiensis, northeast structural genomics3 consortium target bur95a Phyre2 PDB 3npf chain B Region: 28 - 85 Aligned: 55 Modelled: 55 Confidence: 98.4% Identity: 16% PDB header:hydrolase Chain: B: PDB Molecule:putative dipeptidyl-peptidase vi; PDBTitle: crystal structure of a putative dipeptidyl-peptidase vi (bacova_00612)2 from bacteroides ovatus at 1.72 a resolution Phyre2 PDB 3h41 chain A Region: 35 - 90 Aligned: 54 Modelled: 54 Confidence: 97.4% Identity: 24% PDB header:hydrolase Chain: A: PDB Molecule:nlp/p60 family protein; PDBTitle: crystal structure of a nlpc/p60 family protein (bce_2878) from2 bacillus cereus atcc 10987 at 1.79 a resolution Phyre2 PDB 1xov chain A Region: 34 - 86 Aligned: 50 Modelled: 53 Confidence: 96.5% Identity: 10% PDB header:hydrolase Chain: A: PDB Molecule:ply protein; PDBTitle: the crystal structure of the listeria monocytogenes bacteriophage psa2 endolysin plypsa Phyre2 PDB 3m1u chain B Region: 34 - 85 Aligned: 51 Modelled: 51 Confidence: 96.5% Identity: 18% PDB header:hydrolase Chain: B: PDB Molecule:putative gamma-d-glutamyl-l-diamino acid endopeptidase; PDBTitle: crystal structure of a putative gamma-d-glutamyl-l-diamino acid2 endopeptidase (dvu_0896) from desulfovibrio vulgaris hildenborough at3 1.75 a resolution Phyre2 PDB 1wfw chain A Region: 49 - 93 Aligned: 44 Modelled: 45 Confidence: 96.3% Identity: 30% Fold: SH3-like barrel Superfamily: SH3-domain Family: SH3-domain Phyre2 PDB 1csk chain A Region: 49 - 88 Aligned: 40 Modelled: 39 Confidence: 96.0% Identity: 20% Fold: SH3-like barrel Superfamily: SH3-domain Family: SH3-domain Phyre2 PDB 3pe0 chain B Region: 49 - 119 Aligned: 66 Modelled: 71 Confidence: 95.9% Identity: 26% PDB header:structural protein Chain: B: PDB Molecule:plectin; PDBTitle: structure of the central region of the plakin domain of plectin Phyre2 PDB 2dx1 chain A Region: 49 - 120 Aligned: 70 Modelled: 72 Confidence: 95.8% Identity: 9% PDB header:signaling protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4; PDBTitle: crystal structure of rhogef protein asef Phyre2 PDB 3qwy chain A Region: 50 - 88 Aligned: 38 Modelled: 39 Confidence: 95.7% Identity: 18% PDB header:signaling protein Chain: A: PDB Molecule:cell death abnormality protein 2; PDBTitle: ced-2 Phyre2 PDB 1k9a chain B Region: 50 - 90 Aligned: 41 Modelled: 41 Confidence: 95.7% Identity: 20% PDB header:transferase Chain: B: PDB Molecule:carboxyl-terminal src kinase; PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution Phyre2 PDB 1gl5 chain A Region: 49 - 90 Aligned: 41 Modelled: 42 Confidence: 95.7% Identity: 20% Fold: SH3-like barrel Superfamily: SH3-domain Family: SH3-domain Phyre2 PDB 3qwx chain X Region: 50 - 88 Aligned: 38 Modelled: 39 Confidence: 95.6% Identity: 18% PDB header:signaling protein Chain: X: PDB Molecule:cell death abnormality protein 2; PDBTitle: ced-2 1-174 Phyre2 PDB 2x3w chain D Region: 49 - 87 Aligned: 39 Modelled: 39 Confidence: 95.6% Identity: 21% PDB header:endocytosis Chain: D: PDB Molecule:protein kinase c and casein kinase substrate in neurons PDBTitle: structure of mouse syndapin i (crystal form 2) Phyre2 PDB 1k9a chain A domain 1 Region: 49 - 93 Aligned: 45 Modelled: 45 Confidence: 95.6% Identity: 18% Fold: SH3-like barrel Superfamily: SH3-domain Family: SH3-domain Phyre2 PDB 1cka chain A Region: 49 - 87 Aligned: 38 Modelled: 39 Confidence: 95.5% Identity: 16% Fold: SH3-like barrel Superfamily: SH3-domain Family: SH3-domain Phyre2 PDB 2eyy chain A Region: 50 - 98 Aligned: 48 Modelled: 49 Confidence: 95.5% Identity: 17% PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: ct10-regulated kinase isoform i Phyre2 PDB 1ei3 chain E Region: 82 - 172 Aligned: 91 Modelled: 91 Confidence: 94.8% Identity: 14% PDB header: PDB COMPND: Phyre2 PDB 1deq chain O Region: 104 - 172 Aligned: 69 Modelled: 69 Confidence: 94.6% Identity: 13% PDB header: PDB COMPND: Phyre2 PDB 3oja chain B Region: 91 - 171 Aligned: 81 Modelled: 81 Confidence: 94.6% Identity: 11% PDB header:protein binding Chain: B: PDB Molecule:anopheles plasmodium-responsive leucine-rich repeat protein PDBTitle: crystal structure of lrim1/apl1c complex Phyre2 PDB 2wpq chain A Region: 95 - 171 Aligned: 77 Modelled: 77 Confidence: 93.6% Identity: 8% PDB header:membrane protein Chain: A: PDB Molecule:trimeric autotransporter adhesin fragment; PDBTitle: salmonella enterica sada 479-519 fused to gcn4 adaptors (2 sadak3, in-register fusion) Phyre2 PDB 1deq chain F Region: 91 - 171 Aligned: 81 Modelled: 81 Confidence: 93.6% Identity: 6% PDB header: PDB COMPND: Phyre2 1 c2kt8A_ 2 c2krsA_ 3 c2kybA_ 4 c2kq8A_ 5 c3npfB_ 6 c3h41A_ 7 c1xovA_ 8 c3m1uB_ 9 d1wfwa_ 10 d1cska_ 11 c3pe0B_ 12 c2dx1A_ 13 c3qwyA_ 14 c1k9aB_ 15 d1gl5a_ 16 c3qwxX_ 17 c2x3wD_ 18 d1k9aa1 19 d1ckaa_ 20 c2eyyA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 c1ei3E_ 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 c1deqO_ 67 68 c3ojaB_ 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 c2wpqA_ 117 118 119 c1deqF_ 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2kt8A_ 99.0 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:probable surface protein; PDBTitle: solution nmr structure of the cpe1231(468-535) protein from2 clostridium perfringens, northeast structural genomics3 consortium target cpr82b 2 c2krsA_ 98.9 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:probable enterotoxin; PDBTitle: solution nmr structure of sh3 domain from cpf_0587 (fragment2 415-479) from clostridium perfringens. northeast structural3 genomics consortium (nesg) target cpr74a. 3 c2kybA_ 98.6 15 PDB header:toxin Chain: A: PDB Molecule:mannosyl-glycoprotein endo-beta-n-acetylglucosamidase PDBTitle: solution structure of cpr82g from clostridium perfringens. north east2 structural genomics consortium target cpr82g 4 c2kq8A_ 98.6 28 PDB header:hydrolase Chain: A: PDB Molecule:cell wall hydrolase; PDBTitle: solution nmr structure of a domain from bt9727_4915 from2 bacillus thuringiensis, northeast structural genomics3 consortium target bur95a 5 c3npfB_ 98.4 16 PDB header:hydrolase Chain: B: PDB Molecule:putative dipeptidyl-peptidase vi; PDBTitle: crystal structure of a putative dipeptidyl-peptidase vi (bacova_00612)2 from bacteroides ovatus at 1.72 a resolution 6 c3h41A_ 97.4 24 PDB header:hydrolase Chain: A: PDB Molecule:nlp/p60 family protein; PDBTitle: crystal structure of a nlpc/p60 family protein (bce_2878) from2 bacillus cereus atcc 10987 at 1.79 a resolution 7 c1xovA_ 96.5 10 PDB header:hydrolase Chain: A: PDB Molecule:ply protein; PDBTitle: the crystal structure of the listeria monocytogenes bacteriophage psa2 endolysin plypsa 8 c3m1uB_ 96.5 18 PDB header:hydrolase Chain: B: PDB Molecule:putative gamma-d-glutamyl-l-diamino acid endopeptidase; PDBTitle: crystal structure of a putative gamma-d-glutamyl-l-diamino acid2 endopeptidase (dvu_0896) from desulfovibrio vulgaris hildenborough at3 1.75 a resolution 9 d1wfwa_ 96.3 30 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 10 d1cska_ 96.0 20 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 11 c3pe0B_ 95.9 26 PDB header:structural protein Chain: B: PDB Molecule:plectin; PDBTitle: structure of the central region of the plakin domain of plectin 12 c2dx1A_ 95.8 9 PDB header:signaling protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4; PDBTitle: crystal structure of rhogef protein asef 13 c3qwyA_ 95.7 18 PDB header:signaling protein Chain: A: PDB Molecule:cell death abnormality protein 2; PDBTitle: ced-2 14 c1k9aB_ 95.7 20 PDB header:transferase Chain: B: PDB Molecule:carboxyl-terminal src kinase; PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution 15 d1gl5a_ 95.7 20 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 16 c3qwxX_ 95.6 18 PDB header:signaling protein Chain: X: PDB Molecule:cell death abnormality protein 2; PDBTitle: ced-2 1-174 17 c2x3wD_ 95.6 21 PDB header:endocytosis Chain: D: PDB Molecule:protein kinase c and casein kinase substrate in neurons PDBTitle: structure of mouse syndapin i (crystal form 2) 18 d1k9aa1 95.6 18 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 19 d1ckaa_ 95.5 16 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 20 c2eyyA_ 95.5 17 PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: ct10-regulated kinase isoform i 21 c2ct4A_ not modelled 95.4 20 PDB header:signaling protein Chain: A: PDB Molecule:cdc42-interacting protein 4; PDBTitle: solution strutcure of the sh3 domain of the cdc42-2 interacting protein 4 22 d1ng2a2 not modelled 95.4 16 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 23 d1k1za_ not modelled 95.3 21 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 24 c1s1nA_ not modelled 95.2 21 PDB header:cell adhesion Chain: A: PDB Molecule:nephrocystin 1; PDBTitle: sh3 domain of human nephrocystin 25 c1griA_ not modelled 95.1 14 PDB header:signal transduction adaptor Chain: A: PDB Molecule:growth factor bound protein 2; PDBTitle: grb2 26 d1qlya_ not modelled 95.1 21 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 27 c2kbtA_ not modelled 95.1 17 PDB header:signaling protein Chain: A: PDB Molecule:chimera of proto-oncogene vav, linker, PDBTitle: attachment of an nmr-invisible solubility enhancement tag2 (inset) using a sortase-mediated protein ligation method 28 c2rf0D_ not modelled 95.1 23 PDB header:transferase Chain: D: PDB Molecule:mitogen-activated protein kinase kinase kinase 10; PDBTitle: crystal structure of human mixed lineage kinase map3k10 sh3 domain 29 c2dl5A_ not modelled 95.1 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:kiaa0769 protein; PDBTitle: solution structure of the first sh3 domain of human2 kiaa0769 protein 30 c1zlmA_ not modelled 95.1 24 PDB header:signaling protein Chain: A: PDB Molecule:osteoclast stimulating factor 1; PDBTitle: crystal structure of the sh3 domain of human osteoclast2 stimulating factor 31 d1opka1 not modelled 95.1 16 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 32 d1oeba_ not modelled 95.0 16 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 33 c2egcA_ not modelled 95.0 15 PDB header:signaling protein Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a; PDBTitle: solution structure of the fifth sh3 domain from human2 kiaa0418 protein 34 c1z9zA_ not modelled 95.0 18 PDB header:structural protein Chain: A: PDB Molecule:cytoskeleton assembly control protein sla1; PDBTitle: crystal structure of yeast sla1 sh3 domain 3 35 c1ov3A_ not modelled 95.0 16 PDB header:oxidoreductase activator Chain: A: PDB Molecule:neutrophil cytosol factor 1; PDBTitle: structure of the p22phox-p47phox complex 36 d1nega_ not modelled 95.0 22 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 37 c1negA_ not modelled 95.0 22 PDB header:structural protein Chain: A: PDB Molecule:spectrin alpha chain, brain; PDBTitle: crystal structure analysis of n-and c-terminal labeled sh3-2 domain of alpha-chicken spectrin 38 d1uj0a_ not modelled 94.9 26 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 39 d1pwta_ not modelled 94.9 24 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 40 d1wlpb2 not modelled 94.9 16 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 41 c2xmfA_ not modelled 94.9 14 PDB header:motor protein Chain: A: PDB Molecule:myosin 1e sh3; PDBTitle: myosin 1e sh3 42 c1ei3E_ 94.8 14 PDB header: PDB COMPND: 43 c1m9sA_ not modelled 94.8 13 PDB header:signaling protein Chain: A: PDB Molecule:internalin b; PDBTitle: crystal structure of internalin b (inlb), a listeria2 monocytogenes virulence protein containing sh3-like3 domains. 44 d1utia_ not modelled 94.8 16 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 45 c2azsA_ not modelled 94.8 12 PDB header:signaling protein Chain: A: PDB Molecule:sh2-sh3 adapter protein drk; PDBTitle: nmr structure of the n-terminal sh3 domain of drk2 (calculated without noe restraints) 46 c2fg0B_ not modelled 94.8 13 PDB header:hydrolase Chain: B: PDB Molecule:cog0791: cell wall-associated hydrolases (invasion- PDBTitle: crystal structure of a putative gamma-d-glutamyl-l-diamino acid2 endopeptidase (npun_r0659) from nostoc punctiforme pcc 73102 at 1.793 a resolution 47 c1x6gA_ not modelled 94.8 25 PDB header:signaling protein Chain: A: PDB Molecule:megakaryocyte-associated tyrosine-protein kinase; PDBTitle: solution structures of the sh3 domain of human2 megakaryocyte-associated tyrosine-protein kinase. 48 c2df6A_ not modelled 94.8 16 PDB header:signaling protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 7; PDBTitle: crystal structure of the sh3 domain of betapix in complex2 with a high affinity peptide from pak2 49 c2j6kE_ not modelled 94.8 16 PDB header:protein binding Chain: E: PDB Molecule:cd2-associated protein; PDBTitle: n-terminal sh3 domain of cms (cd2ap human homolog) 50 d1fmka1 not modelled 94.8 18 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 51 d1u06a1 not modelled 94.8 24 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 52 c2ekhA_ not modelled 94.8 23 PDB header:signaling protein Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a; PDBTitle: solution structures of the sh3 domain of human kiaa0418 53 c2epdA_ not modelled 94.8 18 PDB header:protein binding Chain: A: PDB Molecule:rho gtpase-activating protein 4; PDBTitle: solution structure of sh3 domain in rho-gtpase-activating2 protein 4 54 d1ov3a2 not modelled 94.8 16 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 55 c1zx6A_ not modelled 94.8 22 PDB header:protein binding Chain: A: PDB Molecule:ypr154wp; PDBTitle: high-resolution crystal structure of yeast pin3 sh3 domain 56 c2fo0A_ not modelled 94.7 18 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform); PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase 57 c1x2pA_ not modelled 94.7 17 PDB header:transferase Chain: A: PDB Molecule:protein arginine n-methyltransferase 2; PDBTitle: solution structure of the sh3 domain of the protein2 arginine n-methyltransferase 2 58 c2cucA_ not modelled 94.7 18 PDB header:signaling protein Chain: A: PDB Molecule:sh3 domain containing ring finger 2; PDBTitle: solution structure of the sh3 domain of the mouse2 hypothetical protein sh3rf2 59 c2enmA_ not modelled 94.7 21 PDB header:endocytosis Chain: A: PDB Molecule:sorting nexin-9; PDBTitle: solution structure of the sh3 domain from mouse sorting2 nexin-9 60 c3cqtA_ not modelled 94.7 21 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn; PDBTitle: n53i v55l mutant of fyn sh3 domain 61 c2dmoA_ not modelled 94.7 28 PDB header:signaling protein Chain: A: PDB Molecule:neutrophil cytosol factor 2; PDBTitle: refined solution structure of the 1st sh3 domain from human2 neutrophil cytosol factor 2 (ncf-2) 62 d1oota_ not modelled 94.6 19 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 63 d1gcqc_ not modelled 94.6 21 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 64 c1w70A_ not modelled 94.6 25 PDB header:sh3 domain Chain: A: PDB Molecule:neutrophil cytosol factor 4; PDBTitle: sh3 domain of p40phox complexed with c-terminal polyproline2 region of p47phox 65 d1uuea_ not modelled 94.6 24 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 66 c1deqO_ 94.6 13 PDB header: PDB COMPND: 67 d1k4us_ not modelled 94.6 15 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 68 c3ojaB_ 94.6 11 PDB header:protein binding Chain: B: PDB Molecule:anopheles plasmodium-responsive leucine-rich repeat protein PDBTitle: crystal structure of lrim1/apl1c complex 69 d1gria2 not modelled 94.6 14 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 70 c2ed0A_ not modelled 94.5 10 PDB header:signaling protein Chain: A: PDB Molecule:abl interactor 2; PDBTitle: solution structure of the sh3 domain of abl interactor 22 (abelson interactor 2) 71 d2rn8a1 not modelled 94.5 24 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 72 d2fo0a1 not modelled 94.5 16 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 73 d1e6ga_ not modelled 94.5 30 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 74 d1u5sa1 not modelled 94.5 14 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 75 c1oplA_ not modelled 94.5 18 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase 76 c2jxbA_ not modelled 94.5 21 PDB header:signaling protein complex Chain: A: PDB Molecule:t-cell surface glycoprotein cd3 epsilon chain, PDBTitle: structure of cd3epsilon-nck2 first sh3 domain complex 77 c2csqA_ not modelled 94.5 11 PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:rim binding protein 2; PDBTitle: solution structure of the second sh3 domain of human rim-2 binding protein 2 78 c2d1xD_ not modelled 94.5 11 PDB header:cell invasion Chain: D: PDB Molecule:cortactin isoform a; PDBTitle: the crystal structure of the cortactin-sh3 domain and amap1-2 peptide complex 79 d1tuca_ not modelled 94.5 24 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 80 d1sema_ not modelled 94.5 19 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 81 c1ng2A_ not modelled 94.4 15 PDB header:oxidoreductase activator Chain: A: PDB Molecule:neutrophil cytosolic factor 1; PDBTitle: structure of autoinhibited p47phox 82 c1zuyB_ not modelled 94.4 8 PDB header:contractile protein Chain: B: PDB Molecule:myosin-5 isoform; PDBTitle: high-resolution structure of yeast myo5 sh3 domain 83 c2nwmA_ not modelled 94.4 20 PDB header:cell adhesion Chain: A: PDB Molecule:vinexin; PDBTitle: solution structure of the first sh3 domain of human vinexin2 and its interaction with the peptides from vinculin 84 d1gcqa_ not modelled 94.3 14 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 85 d1e6ha_ not modelled 94.3 24 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 86 c2ablA_ not modelled 94.3 18 PDB header:transferase Chain: A: PDB Molecule:abl tyrosine kinase; PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase 87 c1wxtA_ not modelled 94.3 32 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein flj21522; PDBTitle: solution structure of the sh3 domain of human hypothetical2 protein flj21522 88 c2l0aA_ not modelled 94.3 21 PDB header:signaling protein Chain: A: PDB Molecule:signal transducing adapter molecule 1; PDBTitle: solution nmr structure of signal transducing adapter molecule 1 stam-12 from homo sapiens, northeast structural genomics consortium target3 hr4479e 89 c2pqhA_ not modelled 94.3 23 PDB header:structural protein Chain: A: PDB Molecule:spectrin alpha chain, brain; PDBTitle: structure of sh3 chimera with a type ii ligand linked to the chain c-2 terminal 90 c2js0A_ not modelled 94.3 15 PDB header:signaling protein Chain: A: PDB Molecule:cytoplasmic protein nck1; PDBTitle: solution structure of second sh3 domain of adaptor nck 91 d1shfa_ not modelled 94.3 18 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 92 c2bz8B_ not modelled 94.2 19 PDB header:sh3 domain Chain: B: PDB Molecule:sh3-domain kinase binding protein 1; PDBTitle: n-terminal sh3 domain of cin85 bound to cbl-b peptide 93 d1ycsb2 not modelled 94.2 13 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 94 c2k2mA_ not modelled 94.2 23 PDB header:signaling protein Chain: A: PDB Molecule:eps8-like protein 1; PDBTitle: structural basis of pxxdy motif recognition in sh3 binding 95 d1jo8a_ not modelled 94.2 11 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 96 c1y57A_ not modelled 94.2 18 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor 97 c2h8hA_ not modelled 94.2 18 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: src kinase in complex with a quinazoline inhibitor 98 c2ct3A_ not modelled 94.2 11 PDB header:signaling protein Chain: A: PDB Molecule:vinexin; PDBTitle: solution structure of the sh3 domain of the vinexin protein 99 c2egaA_ not modelled 94.1 24 PDB header:signaling protein Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a; PDBTitle: solution structure of the first sh3 domain from human2 kiaa0418 protein 100 d1h8ka_ not modelled 94.1 32 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 101 c2c0iA_ not modelled 94.1 14 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983 102 c2yuoA_ not modelled 94.0 13 PDB header:signaling protein Chain: A: PDB Molecule:run and tbc1 domain containing 3; PDBTitle: solution structure of the sh3 domain of mouse run and tbc12 domain containing 3 103 c2yunA_ not modelled 94.0 15 PDB header:protein transport Chain: A: PDB Molecule:nostrin; PDBTitle: solution structure of the sh3 domain of human nostrin 104 c2drmB_ not modelled 94.0 19 PDB header:contractile protein Chain: B: PDB Molecule:acanthamoeba myosin ib; PDBTitle: acanthamoeba myosin i sh3 domain bound to acan125 105 c1wxbA_ not modelled 94.0 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:epidermal growth factor receptor pathway PDBTitle: solution structure of the sh3 domain from human epidermal2 growth factor receptor pathway substrate 8-like protein 106 c1u3oA_ not modelled 94.0 21 PDB header:signaling protein Chain: A: PDB Molecule:huntingtin-associated protein-interacting PDBTitle: solution structure of rat kalirin n-terminal sh3 domain 107 c2dnuA_ not modelled 94.0 14 PDB header:structural genomics, structural protein Chain: A: PDB Molecule:sh3 multiple domains 1; PDBTitle: solution structure of rsgi ruh-061, a sh3 domain from human 108 c2jw4A_ not modelled 93.9 23 PDB header:signaling protein Chain: A: PDB Molecule:cytoplasmic protein nck1; PDBTitle: nmr solution structure of the n-terminal sh3 domain of2 human nckalpha 109 d2v1ra1 not modelled 93.9 16 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 110 c2dilA_ not modelled 93.9 16 PDB header:cell adhesion Chain: A: PDB Molecule:proline-serine-threonine phosphatase-interacting PDBTitle: solution structure of the sh3 domain of the human proline-2 serine-threonine phosphatase-interacting protein 1 111 d1lcka1 not modelled 93.9 17 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 112 c2a28D_ not modelled 93.7 14 PDB header:signaling protein Chain: D: PDB Molecule:bzz1 protein; PDBTitle: atomic-resolution crystal structure of the second sh32 domain of yeast bzz1 determined from a pseudomerohedrally3 twinned crystal 113 c1x27F_ not modelled 93.6 18 PDB header:signaling protein Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck; PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas 114 c1x2qA_ not modelled 93.6 14 PDB header:signaling protein Chain: A: PDB Molecule:signal transducing adapter molecule 2; PDBTitle: solution structure of the sh3 domain of the signal2 transducing adaptor molecule 2 115 d1gbra_ not modelled 93.6 17 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 116 c2wpqA_ 93.6 8 PDB header:membrane protein Chain: A: PDB Molecule:trimeric autotransporter adhesin fragment; PDBTitle: salmonella enterica sada 479-519 fused to gcn4 adaptors (2 sadak3, in-register fusion) 117 c2djqA_ not modelled 93.6 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:sh3 domain containing ring finger 2; PDBTitle: the solution structure of the first sh3 domain of mouse sh32 domain containing ring finger 2 118 d1ov3a1 not modelled 93.6 16 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 119 c1deqF_ 93.6 6 PDB header: PDB COMPND: 120 c2eqiA_ not modelled 93.6 8 PDB header:immune system, hydrolase Chain: A: PDB Molecule:phospholipase c, gamma 2; PDBTitle: solution structure of the sh3 domain from phospholipase c,2 gamma 2

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0