Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	I	K	P	T	F	L	R	R	V	A	I	A	A	L	L	S	G	S	C	F	S	A	A	A	A	P	P	A	P	P	V	S	Y	G	V	E	E	D	V	F	H	P	V	R	A	K	Q	G	M	V	A	S	V	D	A	T	A	T	Q
Secondary structure
SS confidence
Disorder		?	?	?	?																			?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	G	V	D	I	L	K	E	G	G	N	A	V	D	A	A	V	A	V	G	Y	A	L	A	V	T	H	P	Q	A	G	N	L	G	G	G	G	F	M	L	I	R	S	K	N	G	N	T	T	A	I	D	F	R	E	M	A	P	A	K
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	T	R	D	M	F	L	D	D	Q	G	N	P	D	S	K	K	S	L	T	S	H	L	A	S	G	T	P	G	T	V	A	G	F	S	L	A	L	D	K	Y	G	T	M	P	L	N	K	V	V	Q	P	A	F	K	L	A	R	D	G
Secondary structure
SS confidence
Disorder										?	?	?	?	?	?	?	?		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		F	I	V	N	D	A	L	A	D	D	L	K	T	Y	G	S	E	V	L	P	N	H	E	N	S	K	A	I	F	W	K	E	G	E	P	L	K	K	G	D	T	L	V	Q	A	N	L	A	K	S	L	E	M	I	A	E	N	G	P	D
Secondary structure
SS confidence
Disorder																																																												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		E	F	Y	K	G	T	I	A	E	Q	I	A	Q	E	M	Q	K	N	G	G	L	I	T	K	E	D	L	A	A	Y	K	A	V	E	R	T	P	I	S	G	D	Y	R	G	Y	Q	V	Y	S	M	P	P	P	S	S	G	G	I	H	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		V	Q	I	L	N	I	L	E	N	F	D	M	K	K	Y	G	F	G	S	A	D	A	M	Q	I	M	A	E	A	E	K	Y	A	Y	A	D	R	S	E	Y	L	G	D	P	D	F	V	K	V	P	W	Q	A	L	T	N	K	A	Y	A
Secondary structure
SS confidence
Disorder													?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		K	S	I	A	D	Q	I	D	I	N	K	A	K	P	S	S	E	I	R	P	G	K	L	A	P	Y	E	S	N	Q	T	T	H	Y	S	V	V	D	K	D	G	N	A	V	A	V	T	Y	T	L	N	T	T	F	G	T	G	I	V	A
Secondary structure
SS confidence
Disorder										?	?	?	?	?	?	?	?				?					?																									?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		G	E	S	G	I	L	L	N	N	Q	M	D	D	F	S	A	K	P	G	V	P	N	V	Y	G	L	V	G	G	D	A	N	A	V	G	P	N	K	R	P	L	S	S	M	S	P	T	I	V	V	K	D	G	K	T	W	L	V	T	G
Secondary structure
SS confidence
Disorder																						?		?		?	?		?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		S	P	G	G	S	R	I	I	T	T	V	L	Q	M	V	V	N	S	I	D	Y	G	L	N	V	A	E	A	T	N	A	P	R	F	H	H	Q	W	L	P	D	E	L	R	V	E	K	G	F	S	P	D	T	L	K	L	L	E	A	K
Secondary structure
SS confidence
Disorder				?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580
Sequence		G	Q	K	V	A	L	K	E	A	M	G	S	T	Q	S	I	M	V	G	P	D	G	E	L	Y	G	A	S	D	P	R	S	V	D	D	L	T	A	G	Y
Secondary structure
SS confidence
Disorder							?	?																											?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2nlz chain A domain 1 Region: 31 - 580 Aligned: 521 Modelled: 540 Confidence: 100.0% Identity: 31% Fold: Ntn hydrolase-like Superfamily: N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family: Gamma-glutamyltranspeptidase-like Phyre2 PDB 2e0w chain A Region: 29 - 580 Aligned: 496 Modelled: 505 Confidence: 100.0% Identity: 100% PDB header:transferase Chain: A: PDB Molecule:gamma-glutamyltranspeptidase; PDBTitle: t391a precursor mutant protein of gamma-glutamyltranspeptidase from2 escherichia coli Phyre2 PDB 2i3o chain A domain 1 Region: 39 - 580 Aligned: 495 Modelled: 509 Confidence: 100.0% Identity: 24% Fold: Ntn hydrolase-like Superfamily: N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family: Gamma-glutamyltranspeptidase-like Phyre2 PDB 2z8j chain A Region: 38 - 387 Aligned: 350 Modelled: 350 Confidence: 100.0% Identity: 100% PDB header:transferase Chain: A: PDB Molecule:gamma-glutamyltranspeptidase; PDBTitle: crystal structure of escherichia coli gamma-2 glutamyltranspeptidase in complex with azaserine prepared3 in the dark Phyre2 PDB 2v36 chain A Region: 36 - 399 Aligned: 357 Modelled: 364 Confidence: 100.0% Identity: 40% PDB header:transferase Chain: A: PDB Molecule:gamma-glutamyltranspeptidase large chain; PDBTitle: crystal structure of gamma-glutamyl transferase from2 bacillus subtilis Phyre2 PDB 2qm6 chain C Region: 46 - 390 Aligned: 345 Modelled: 345 Confidence: 100.0% Identity: 49% PDB header:transferase Chain: C: PDB Molecule:gamma-glutamyltranspeptidase; PDBTitle: crystal structure of helicobacter pylori gamma-glutamyltranspeptidase2 in complex with glutamate Phyre2 PDB 3g9k chain D Region: 48 - 357 Aligned: 276 Modelled: 283 Confidence: 100.0% Identity: 38% PDB header:hydrolase Chain: D: PDB Molecule:capsule biosynthesis protein capd; PDBTitle: crystal structure of bacillus anthracis transpeptidase enzyme capd Phyre2 PDB 2e0y chain B Region: 391 - 580 Aligned: 180 Modelled: 190 Confidence: 100.0% Identity: 96% PDB header:transferase Chain: B: PDB Molecule:gamma-glutamyltranspeptidase; PDBTitle: crystal structure of the samarium derivative of mature gamma-2 glutamyltranspeptidase from escherichia coli Phyre2 PDB 2nqo chain B Region: 391 - 572 Aligned: 182 Modelled: 182 Confidence: 100.0% Identity: 58% PDB header:transferase Chain: B: PDB Molecule:gamma-glutamyltranspeptidase; PDBTitle: crystal structure of helicobacter pylori gamma-glutamyltranspeptidase Phyre2 PDB 2v36 chain D Region: 391 - 580 Aligned: 178 Modelled: 190 Confidence: 100.0% Identity: 42% PDB header:transferase Chain: D: PDB Molecule:gamma-glutamyltranspeptidase small chain; PDBTitle: crystal structure of gamma-glutamyl transferase from2 bacillus subtilis Phyre2 PDB 3ga9 chain S Region: 391 - 579 Aligned: 162 Modelled: 164 Confidence: 100.0% Identity: 33% PDB header:hydrolase Chain: S: PDB Molecule:capsule biosynthesis protein capd; PDBTitle: crystal structure of bacillus anthracis transpeptidase enzyme capd,2 crystal form ii Phyre2 PDB 1apy chain A Region: 56 - 95 Aligned: 40 Modelled: 40 Confidence: 94.9% Identity: 25% PDB header:hydrolase Chain: A: PDB Molecule:aspartylglucosaminidase; PDBTitle: human aspartylglucosaminidase Phyre2 PDB 1t3m chain A Region: 56 - 95 Aligned: 40 Modelled: 40 Confidence: 94.9% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:putative l-asparaginase; PDBTitle: structure of the isoaspartyl peptidase with l-asparaginase2 activity from e. coli Phyre2 PDB 2gez chain E Region: 56 - 95 Aligned: 40 Modelled: 40 Confidence: 94.4% Identity: 23% PDB header:hydrolase Chain: E: PDB Molecule:l-asparaginase alpha subunit; PDBTitle: crystal structure of potassium-independent plant asparaginase Phyre2 PDB 2zak chain B Region: 56 - 95 Aligned: 40 Modelled: 40 Confidence: 93.4% Identity: 18% PDB header:hydrolase Chain: B: PDB Molecule:l-asparaginase precursor; PDBTitle: orthorhombic crystal structure of precursor e. coli isoaspartyl2 peptidase/l-asparaginase (ecaiii) with active-site t179a mutation Phyre2 PDB 1p4v chain A Region: 349 - 568 Aligned: 152 Modelled: 160 Confidence: 92.9% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:n(4)-(beta-n-acetylglucosaminyl)-l-asparaginase PDBTitle: crystal structure of the glycosylasparaginase precursor2 d151n mutant with glycine Phyre2 PDB 2gac chain A Region: 57 - 83 Aligned: 27 Modelled: 27 Confidence: 92.4% Identity: 26% PDB header:hydrolase Chain: A: PDB Molecule:glycosylasparaginase; PDBTitle: t152c mutant glycosylasparaginase from flavobacterium2 meningosepticum Phyre2 PDB 2a8l chain B Region: 57 - 95 Aligned: 39 Modelled: 39 Confidence: 92.2% Identity: 26% PDB header:hydrolase Chain: B: PDB Molecule:threonine aspartase 1; PDBTitle: crystal structure of human taspase1 (t234a mutant) Phyre2 PDB 1apz chain B Region: 391 - 510 Aligned: 81 Modelled: 81 Confidence: 85.9% Identity: 19% PDB header:complex (hydrolase/peptide) Chain: B: PDB Molecule:aspartylglucosaminidase; PDBTitle: human aspartylglucosaminidase complex with reaction product Phyre2 PDB 3cuq chain A Region: 238 - 267 Aligned: 29 Modelled: 30 Confidence: 85.6% Identity: 45% PDB header:protein transport Chain: A: PDB Molecule:vacuolar-sorting protein snf8; PDBTitle: integrated structural and functional model of the human escrt-ii2 complex Phyre2 1 d2nlza1 2 c2e0wA_ 3 d2i3oa1 4 c2z8jA_ 5 c2v36A_ 6 c2qm6C_ 7 c3g9kD_ 8 c2e0yB_ 9 c2nqoB_ 10 c2v36D_ 11 c3ga9S_ 12 c1apyA_ 13 c1t3mA_ 14 c2gezE_ 15 c2zakB_ 16 c1p4vA_ 17 c2gacA_ 18 c2a8lB_ 19 c1apzB_ 20 c3cuqA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d2nlza1 100.0 31 Fold:Ntn hydrolase-like Superfamily:N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family:Gamma-glutamyltranspeptidase-like 2 c2e0wA_ 100.0 100 PDB header:transferase Chain: A: PDB Molecule:gamma-glutamyltranspeptidase; PDBTitle: t391a precursor mutant protein of gamma-glutamyltranspeptidase from2 escherichia coli 3 d2i3oa1 100.0 24 Fold:Ntn hydrolase-like Superfamily:N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family:Gamma-glutamyltranspeptidase-like 4 c2z8jA_ 100.0 100 PDB header:transferase Chain: A: PDB Molecule:gamma-glutamyltranspeptidase; PDBTitle: crystal structure of escherichia coli gamma-2 glutamyltranspeptidase in complex with azaserine prepared3 in the dark 5 c2v36A_ 100.0 40 PDB header:transferase Chain: A: PDB Molecule:gamma-glutamyltranspeptidase large chain; PDBTitle: crystal structure of gamma-glutamyl transferase from2 bacillus subtilis 6 c2qm6C_ 100.0 49 PDB header:transferase Chain: C: PDB Molecule:gamma-glutamyltranspeptidase; PDBTitle: crystal structure of helicobacter pylori gamma-glutamyltranspeptidase2 in complex with glutamate 7 c3g9kD_ 100.0 38 PDB header:hydrolase Chain: D: PDB Molecule:capsule biosynthesis protein capd; PDBTitle: crystal structure of bacillus anthracis transpeptidase enzyme capd 8 c2e0yB_ 100.0 96 PDB header:transferase Chain: B: PDB Molecule:gamma-glutamyltranspeptidase; PDBTitle: crystal structure of the samarium derivative of mature gamma-2 glutamyltranspeptidase from escherichia coli 9 c2nqoB_ 100.0 58 PDB header:transferase Chain: B: PDB Molecule:gamma-glutamyltranspeptidase; PDBTitle: crystal structure of helicobacter pylori gamma-glutamyltranspeptidase 10 c2v36D_ 100.0 42 PDB header:transferase Chain: D: PDB Molecule:gamma-glutamyltranspeptidase small chain; PDBTitle: crystal structure of gamma-glutamyl transferase from2 bacillus subtilis 11 c3ga9S_ 100.0 33 PDB header:hydrolase Chain: S: PDB Molecule:capsule biosynthesis protein capd; PDBTitle: crystal structure of bacillus anthracis transpeptidase enzyme capd,2 crystal form ii 12 c1apyA_ 94.9 25 PDB header:hydrolase Chain: A: PDB Molecule:aspartylglucosaminidase; PDBTitle: human aspartylglucosaminidase 13 c1t3mA_ 94.9 18 PDB header:hydrolase Chain: A: PDB Molecule:putative l-asparaginase; PDBTitle: structure of the isoaspartyl peptidase with l-asparaginase2 activity from e. coli 14 c2gezE_ 94.4 23 PDB header:hydrolase Chain: E: PDB Molecule:l-asparaginase alpha subunit; PDBTitle: crystal structure of potassium-independent plant asparaginase 15 c2zakB_ 93.4 18 PDB header:hydrolase Chain: B: PDB Molecule:l-asparaginase precursor; PDBTitle: orthorhombic crystal structure of precursor e. coli isoaspartyl2 peptidase/l-asparaginase (ecaiii) with active-site t179a mutation 16 c1p4vA_ 92.9 18 PDB header:hydrolase Chain: A: PDB Molecule:n(4)-(beta-n-acetylglucosaminyl)-l-asparaginase PDBTitle: crystal structure of the glycosylasparaginase precursor2 d151n mutant with glycine 17 c2gacA_ 92.4 26 PDB header:hydrolase Chain: A: PDB Molecule:glycosylasparaginase; PDBTitle: t152c mutant glycosylasparaginase from flavobacterium2 meningosepticum 18 c2a8lB_ 92.2 26 PDB header:hydrolase Chain: B: PDB Molecule:threonine aspartase 1; PDBTitle: crystal structure of human taspase1 (t234a mutant) 19 c1apzB_ 85.9 19 PDB header:complex (hydrolase/peptide) Chain: B: PDB Molecule:aspartylglucosaminidase; PDBTitle: human aspartylglucosaminidase complex with reaction product 20 c3cuqA_ 85.6 45 PDB header:protein transport Chain: A: PDB Molecule:vacuolar-sorting protein snf8; PDBTitle: integrated structural and functional model of the human escrt-ii2 complex 21 c2zmeA_ not modelled 85.4 45 PDB header:protein transport Chain: A: PDB Molecule:vacuolar-sorting protein snf8; PDBTitle: integrated structural and functional model of the human escrt-ii2 complex 22 c1u5tA_ not modelled 84.8 28 PDB header:transport protein Chain: A: PDB Molecule:appears to be functionally related to snf7; PDBTitle: structure of the escrt-ii endosomal trafficking complex 23 d1u5ta1 not modelled 78.9 26 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Vacuolar sorting protein domain 24 c1w7pD_ not modelled 72.5 33 PDB header:protein transport Chain: D: PDB Molecule:vps36p, ylr417w; PDBTitle: the crystal structure of endosomal complex escrt-ii2 (vps22/vps25/vps36) 25 c1u5tB_ not modelled 69.7 37 PDB header:transport protein Chain: B: PDB Molecule:defective in vacuolar protein sorting; vps36p; PDBTitle: structure of the escrt-ii endosomal trafficking complex 26 c2zmeB_ not modelled 69.2 19 PDB header:protein transport Chain: B: PDB Molecule:vacuolar protein-sorting-associated protein 36; PDBTitle: integrated structural and functional model of the human escrt-ii2 complex 27 d1jq5a_ not modelled 64.7 23 Fold:Dehydroquinate synthase-like Superfamily:Dehydroquinate synthase-like Family:Iron-containing alcohol dehydrogenase 28 c1t3mD_ not modelled 62.1 27 PDB header:hydrolase Chain: D: PDB Molecule:putative l-asparaginase; PDBTitle: structure of the isoaspartyl peptidase with l-asparaginase2 activity from e. coli 29 c1jn9B_ not modelled 62.1 27 PDB header:hydrolase Chain: B: PDB Molecule:putative l-asparaginase; PDBTitle: structure of putative asparaginase encoded by escherichia coli ybik2 gene 30 c1t3mB_ not modelled 62.1 27 PDB header:hydrolase Chain: B: PDB Molecule:putative l-asparaginase; PDBTitle: structure of the isoaspartyl peptidase with l-asparaginase2 activity from e. coli 31 c2zalD_ not modelled 58.9 27 PDB header:hydrolase Chain: D: PDB Molecule:l-asparaginase; PDBTitle: crystal structure of e. coli isoaspartyl aminopeptidase/l-asparaginase2 in complex with l-aspartate 32 c2gacD_ not modelled 55.0 19 PDB header:hydrolase Chain: D: PDB Molecule:glycosylasparaginase; PDBTitle: t152c mutant glycosylasparaginase from flavobacterium2 meningosepticum 33 c2gezF_ not modelled 53.6 21 PDB header:hydrolase Chain: F: PDB Molecule:l-asparaginase beta subunit; PDBTitle: crystal structure of potassium-independent plant asparaginase 34 c1k2xB_ not modelled 51.1 27 PDB header:hydrolase Chain: B: PDB Molecule:putative l-asparaginase; PDBTitle: crystal structure of putative asparaginase encoded by escherichia coli2 ybik gene 35 c1k2xD_ not modelled 51.1 27 PDB header:hydrolase Chain: D: PDB Molecule:putative l-asparaginase; PDBTitle: crystal structure of putative asparaginase encoded by escherichia coli2 ybik gene 36 c1jn9D_ not modelled 51.1 27 PDB header:hydrolase Chain: D: PDB Molecule:putative l-asparaginase; PDBTitle: structure of putative asparaginase encoded by escherichia coli ybik2 gene 37 c2zalB_ not modelled 48.3 27 PDB header:hydrolase Chain: B: PDB Molecule:l-asparaginase; PDBTitle: crystal structure of e. coli isoaspartyl aminopeptidase/l-asparaginase2 in complex with l-aspartate 38 c3rf7A_ not modelled 31.4 16 PDB header:oxidoreductase Chain: A: PDB Molecule:iron-containing alcohol dehydrogenase; PDBTitle: crystal structure of an iron-containing alcohol dehydrogenase2 (sden_2133) from shewanella denitrificans os-217 at 2.12 a resolution 39 c2wl8D_ not modelled 31.2 19 PDB header:protein transport Chain: D: PDB Molecule:peroxisomal biogenesis factor 19; PDBTitle: x-ray crystal structure of pex19p 40 d2fi0a1 not modelled 28.9 19 Fold:SP0561-like Superfamily:SP0561-like Family:SP0561-like 41 d1u2ka_ not modelled 26.3 11 Fold:Heme-dependent peroxidases Superfamily:Heme-dependent peroxidases Family:Catalase-peroxidase KatG 42 c3bt3B_ not modelled 25.4 13 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:glyoxalase-related enzyme, arac type; PDBTitle: crystal structure of a glyoxalase-related enzyme from clostridium2 phytofermentans 43 c3h7hA_ not modelled 24.1 11 PDB header:transcription Chain: A: PDB Molecule:transcription elongation factor spt4; PDBTitle: crystal structure of the human transcription elongation factor dsif,2 hspt4/hspt5 (176-273) 44 c3gxqB_ not modelled 23.9 50 PDB header:dna binding protein/dna Chain: B: PDB Molecule:putative regulator of transfer genes arta; PDBTitle: structure of arta and dna complex 45 d1o2da_ not modelled 23.7 27 Fold:Dehydroquinate synthase-like Superfamily:Dehydroquinate synthase-like Family:Iron-containing alcohol dehydrogenase 46 d2ccaa1 not modelled 23.3 15 Fold:Heme-dependent peroxidases Superfamily:Heme-dependent peroxidases Family:Catalase-peroxidase KatG 47 c1udsA_ not modelled 21.1 17 PDB header:transferase Chain: A: PDB Molecule:ribonuclease ph; PDBTitle: crystal structure of the trna processing enzyme rnase ph r126a mutant2 from aquifex aeolicus 48 d1oj7a_ not modelled 20.8 20 Fold:Dehydroquinate synthase-like Superfamily:Dehydroquinate synthase-like Family:Iron-containing alcohol dehydrogenase 49 c2kmvA_ not modelled 20.5 13 PDB header:hydrolase Chain: A: PDB Molecule:copper-transporting atpase 1; PDBTitle: solution structure of the nucleotide binding domain of the2 human menkes protein in the atp-free form 50 c3hkmB_ not modelled 19.9 26 PDB header:hydrolase Chain: B: PDB Molecule:os03g0854200 protein; PDBTitle: crystal structure of rice(oryza sativa) rrp46 51 d1u5tb1 not modelled 19.4 33 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Vacuolar sorting protein domain 52 c2qntA_ not modelled 19.0 25 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein atu1872; PDBTitle: crystal structure of protein of unknown function from agrobacterium2 tumefaciens str. c58 53 d2nn6f1 not modelled 17.6 33 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:Ribonuclease PH domain 1-like 54 d1r6la1 not modelled 17.2 11 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:Ribonuclease PH domain 1-like 55 c2nn6D_ not modelled 16.9 21 PDB header:hydrolase/transferase Chain: D: PDB Molecule:exosome complex exonuclease rrp46; PDBTitle: structure of the human rna exosome composed of rrp41, rrp45,2 rrp46, rrp43, mtr3, rrp42, csl4, rrp4, and rrp40 56 d2nn6b1 not modelled 16.6 22 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:Ribonuclease PH domain 1-like 57 c3b4tC_ not modelled 16.4 32 PDB header:transferase Chain: C: PDB Molecule:ribonuclease ph; PDBTitle: crystal structure of mycobacterium tuberculosis rnase ph, the2 mycobacterium tuberculosis structural genomics consortium target3 rv1340 58 d1udsa1 not modelled 16.1 17 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:Ribonuclease PH domain 1-like 59 d2nn6a1 not modelled 15.9 33 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:Ribonuclease PH domain 1-like 60 d1a0da_ not modelled 15.7 24 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 61 d2nn6e1 not modelled 15.6 39 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:Ribonuclease PH domain 1-like 62 d1vlja_ not modelled 15.6 25 Fold:Dehydroquinate synthase-like Superfamily:Dehydroquinate synthase-like Family:Iron-containing alcohol dehydrogenase 63 d2je6b1 not modelled 15.6 11 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:Ribonuclease PH domain 1-like 64 c1u2jC_ not modelled 15.6 9 PDB header:oxidoreductase Chain: C: PDB Molecule:peroxidase/catalase hpi; PDBTitle: crystal structure of the c-terminal domain from the2 catalase-peroxidase katg of escherichia coli (p21 21 21) 65 c2rk9B_ not modelled 14.8 14 PDB header:oxidoreductase Chain: B: PDB Molecule:glyoxalase/bleomycin resistance protein/dioxygenase; PDBTitle: the crystal structure of a glyoxalase/bleomycin resistance2 protein/dioxygenase superfamily member from vibrio splendidus 12b01 66 d2ba0g1 not modelled 13.9 33 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:Ribonuclease PH domain 1-like 67 c3itwA_ not modelled 13.8 26 PDB header:peptide binding protein Chain: A: PDB Molecule:protein tiox; PDBTitle: crystal structure of tiox from micromonospora sp. ml1 68 d2nn6d1 not modelled 13.5 6 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:Ribonuclease PH domain 1-like 69 c2wnrB_ not modelled 13.3 32 PDB header:hydrolase Chain: B: PDB Molecule:probable exosome complex exonuclease 1; PDBTitle: the structure of methanothermobacter thermautotrophicus2 exosome core assembly 70 d1kq3a_ not modelled 12.4 20 Fold:Dehydroquinate synthase-like Superfamily:Dehydroquinate synthase-like Family:Iron-containing alcohol dehydrogenase 71 c2nn6F_ not modelled 12.1 33 PDB header:hydrolase/transferase Chain: F: PDB Molecule:exosome component 6; PDBTitle: structure of the human rna exosome composed of rrp41, rrp45,2 rrp46, rrp43, mtr3, rrp42, csl4, rrp4, and rrp40 72 d1ny9a_ not modelled 12.1 11 Fold:Antibiotic binding domain of TipA-like multidrug resistance regulators Superfamily:Antibiotic binding domain of TipA-like multidrug resistance regulators Family:Antibiotic binding domain of TipA-like multidrug resistance regulators 73 c1ny9A_ not modelled 12.1 11 PDB header:transcription Chain: A: PDB Molecule:transcriptional activator tipa-s; PDBTitle: antibiotic binding domain of a tipa-class multidrug2 resistance transcriptional regulator 74 c2e5yA_ not modelled 11.9 17 PDB header:hydrolase Chain: A: PDB Molecule:atp synthase epsilon chain; PDBTitle: epsilon subunit and atp complex of f1f0-atp synthase from2 the thermophilic bacillus ps3 75 c2wp8B_ not modelled 11.9 11 PDB header:hydrolase Chain: B: PDB Molecule:exosome complex component ski6; PDBTitle: yeast rrp44 nuclease 76 d1mwva1 not modelled 11.6 9 Fold:Heme-dependent peroxidases Superfamily:Heme-dependent peroxidases Family:Catalase-peroxidase KatG 77 c2qz5A_ not modelled 11.2 19 PDB header:signaling protein, lipid binding protein Chain: A: PDB Molecule:axin interactor, dorsalization associated PDBTitle: crystal structure of the c-terminal domain of aida 78 c3epzA_ not modelled 11.0 26 PDB header:transferase Chain: A: PDB Molecule:dna (cytosine-5)-methyltransferase 1; PDBTitle: structure of the replication foci-targeting sequence of human dna2 cytosine methyltransferase dnmt1 79 d2qalk1 not modelled 11.0 26 Fold:Ribonuclease H-like motif Superfamily:Translational machinery components Family:Ribosomal protein L18 and S11 80 c2br2G_ not modelled 10.9 39 PDB header:hydrolase Chain: G: PDB Molecule:exosome complex exonuclease 2; PDBTitle: rnase ph core of the archaeal exosome 81 d1oysa1 not modelled 10.9 11 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:Ribonuclease PH domain 1-like 82 c2zkqk_ not modelled 10.9 22 PDB header:ribosomal protein/rna Chain: K: PDB Molecule: PDBTitle: structure of a mammalian ribosomal 40s subunit within an2 80s complex obtained by docking homology models of the rna3 and proteins into an 8.7 a cryo-em map 83 c3dd6A_ not modelled 10.6 17 PDB header:transferase Chain: A: PDB Molecule:ribonuclease ph; PDBTitle: crystal structure of rph, an exoribonuclease from bacillus2 anthracis at 1.7 a resolution 84 d2je6a1 not modelled 10.5 39 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:Ribonuclease PH domain 1-like 85 c2koyA_ not modelled 10.5 12 PDB header:metal transport Chain: A: PDB Molecule:copper-transporting atpase 2; PDBTitle: structure of the e1064a mutant of the n-domain of wilson disease2 associated protein 86 d1huwa_ not modelled 10.4 15 Fold:4-helical cytokines Superfamily:4-helical cytokines Family:Long-chain cytokines 87 c3bvkC_ not modelled 10.3 13 PDB header:oxidoreductase Chain: C: PDB Molecule:ferritin; PDBTitle: structural basis for the iron uptake mechanism of helicobacter pylori2 ferritin 88 d1ub2a1 not modelled 10.0 12 Fold:Heme-dependent peroxidases Superfamily:Heme-dependent peroxidases Family:Catalase-peroxidase KatG 89 c2arfA_ not modelled 9.9 14 PDB header:hydrolase Chain: A: PDB Molecule:wilson disease atpase; PDBTitle: solution structure of the wilson atpase n-domain in the2 presence of atp 90 d2i09a2 not modelled 9.9 20 Fold:DeoB insert domain-like Superfamily:DeoB insert domain-like Family:DeoB insert domain-like 91 d1v74a_ not modelled 9.5 12 Fold:Colicin D/E5 nuclease domain Superfamily:Colicin D/E5 nuclease domain Family:Colicin D nuclease domain 92 c3bfjK_ not modelled 9.4 18 PDB header:oxidoreductase Chain: K: PDB Molecule:1,3-propanediol oxidoreductase; PDBTitle: crystal structure analysis of 1,3-propanediol oxidoreductase 93 d3bzka1 not modelled 9.4 29 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Tex HhH-containing domain-like 94 d1itka1 not modelled 9.4 12 Fold:Heme-dependent peroxidases Superfamily:Heme-dependent peroxidases Family:Catalase-peroxidase KatG 95 c2rq7A_ not modelled 9.3 16 PDB header:hydrolase Chain: A: PDB Molecule:atp synthase epsilon chain; PDBTitle: solution structure of the epsilon subunit chimera combining2 the n-terminal beta-sandwich domain from t. elongatus bp-13 f1 and the c-terminal alpha-helical domain from spinach4 chloroplast f1 96 c2rbbB_ not modelled 9.2 13 PDB header:oxidoreductase Chain: B: PDB Molecule:glyoxalase/bleomycin resistance protein/dioxygenase; PDBTitle: crystal structure of a glyoxalase/bleomycin resistance2 protein/dioxygenase family enzyme from burkholderia phytofirmans psjn 97 c2oudA_ not modelled 9.1 24 PDB header:hydrolase Chain: A: PDB Molecule:dual specificity protein phosphatase 10; PDBTitle: crystal structure of the catalytic domain of human mkp5 98 c2czhB_ not modelled 9.0 33 PDB header:hydrolase Chain: B: PDB Molecule:inositol monophosphatase 2; PDBTitle: crystal structure of human myo-inositol monophosphatase 22 (impa2) with phosphate ion (orthorhombic form) 99 d1ub2a2 not modelled 8.9 15 Fold:Heme-dependent peroxidases Superfamily:Heme-dependent peroxidases Family:Catalase-peroxidase KatG

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0