PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2nn6D_

Fold library id	PDB Header	Molecule	Title
c2nn6D_	PDB header: hydrolase/transferase	Chain: D: PDB Molecule: exosome complex exonuclease rrp46;	PDBTitle: structure of the human rna exosome composed of rrp41, rrp45,2 rrp46, rrp43, mtr3, rrp42, csl4, rrp4, and rrp40

Links to external resources
Added to library: Tue Mar 16 12:04:00 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence G C S L R H F A C E Q N L L S R P D G S A S F L Q G D T S V L A G V Y G P A E V K N K A T L E V I L R P K I G L P G V A E K S R E R L I R N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S S S S T T
S S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence T C E A V V L G T L H P R T S I T V V L Q V V S D A G S L L A C C L N A A C M A L V D A G V P M R A L F C G V A C A L D S D G T L V L D P T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G
S S S
S S
T T
S S
T T
S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . .

Sequence S K Q E K E A R A V L T F A L D S V E R K L L M S S T K G L Y S D T E L Q Q C L A A A Q A A S Q H V F R F Y R E S L Q R R Y S K S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S T T T
S
T
-

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	G	C	S	L	R	H	F	A	C	E	Q	N	L	L	S	R	P	D	G	S	A	S	F	L	Q	G	D	T	S	V	L	A	G	V	Y	G	P	A	E	V	K	N	K	A	T	L	E	V	I	L	R	P	K	I	G	L	P	G	V	A	E	K	S	R	E	R	L	I	R	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												S			S	S	S	S								T	T																										S	S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	T	C	E	A	V	V	L	G	T	L	H	P	R	T	S	I	T	V	V	L	Q	V	V	S	D	A	G	S	L	L	A	C	C	L	N	A	A	C	M	A	L	V	D	A	G	V	P	M	R	A	L	F	C	G	V	A	C	A	L	D	S	D	G	T	L	V	L	D	P	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							G	G	G		S	S	S													S	S																	T	T				S	S											T	T						S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.
Sequence	S	K	Q	E	K	E	A	R	A	V	L	T	F	A	L	D	S	V	E	R	K	L	L	M	S	S	T	K	G	L	Y	S	D	T	E	L	Q	Q	C	L	A	A	A	Q	A	A	S	Q	H	V	F	R	F	Y	R	E	S	L	Q	R	R	Y	S	K	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								S									T	T	T											S																																T			-