PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2nn6F_

Fold library id	PDB Header	Molecule	Title
c2nn6F_	PDB header: hydrolase/transferase	Chain: F: PDB Molecule: exosome component 6;	PDBTitle: structure of the human rna exosome composed of rrp41, rrp45,2 rrp46, rrp43, mtr3, rrp42, csl4, rrp4, and rrp40

Links to external resources
Added to library: Tue Mar 16 13:36:08 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence G T R D P T R L R P V Y A R A G L L S Q A K G S A Y L E A G G T K V L C A V S G P R Q A L R G R L L C D F R R A P F A G R R R R A P P G G C

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
S
S S S S
S S S
B
T T S S S S
S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence E E R E L A L A L Q E A L E P A V R L G R Y P R A Q L E V S A L L L E D G G S A L A A A L T A A A L A L A D A G V E M Y D L V V G C G L S L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T B
S T T S B T
S S
B S S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence A P G P A P T W L L D P T R L E E E R A A A G L T V A L M P V L N Q V A G L L G S G E G G L T E S W A E A V R L G L E G C Q R L Y P V L Q Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S S
S S
T T T G G G
S S T T T T
S S
T T T T

. . . . . . . . . 220 . . .

Sequence S L V R A A R R R G A A A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	G	T	R	D	P	T	R	L	R	P	V	Y	A	R	A	G	L	L	S	Q	A	K	G	S	A	Y	L	E	A	G	G	T	K	V	L	C	A	V	S	G	P	R	Q	A	L	R	G	R	L	L	C	D	F	R	R	A	P	F	A	G	R	R	R	R	A	P	P	G	G	C
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					S	S										S			S	S	S	S							S	S	S															B											T	T	S	S	S	S				S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	E	E	R	E	L	A	L	A	L	Q	E	A	L	E	P	A	V	R	L	G	R	Y	P	R	A	Q	L	E	V	S	A	L	L	L	E	D	G	G	S	A	L	A	A	A	L	T	A	A	A	L	A	L	A	D	A	G	V	E	M	Y	D	L	V	V	G	C	G	L	S	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)														T	T	T	B		S	T	T	S	B	T														S	S																				B	S	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	A	P	G	P	A	P	T	W	L	L	D	P	T	R	L	E	E	E	R	A	A	A	G	L	T	V	A	L	M	P	V	L	N	Q	V	A	G	L	L	G	S	G	E	G	G	L	T	E	S	W	A	E	A	V	R	L	G	L	E	G	C	Q	R	L	Y	P	V	L	Q	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S		S	S					S	S			T	T	T	G	G	G		S	S								T	T	T	T											S	S		T	T	T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.
Sequence	S	L	V	R	A	A	R	R	R	G	A	A	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											T	T